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Advances in molecular preclinical therapy mediated by imaging (60 visite) (PDF pubblico 78 visite)

Greco A, Albanese S, Auletta L, De Carlo F, Salvatore M, Howard CM, Claudio PP

Q J Nucl Med Mol Imaging (ISSN: 1827-1936electronic, 1824-4785linking), 2017 Mar; 61(1): 76-94.

Tipo di articolo: Journal Article, Review,

Impact factor: 2.481

Impact factor a 5 anni: 2.16


Parole chiave: Animals, Diagnostic Imaging, Methods, Drug Delivery Systems, Humans, Neoplasms, Therapy, Precision Medicine,

Url: Non disponibile.

Several advances have been made toward understanding the biology of cancer and most of them are due to robust genetic studies that led to the scientific recognition that although many patients have the same type of cancer their tumors may have harbored different molecular alterations. Personalized therapy and the development of advanced techniques of preclinical imaging and new murine models of disease are emerging concepts that are allowing mapping of disease markers in vivo and in some cases also receptor targeted therapy. Aim of this review is to illustrate some emerging models of disease that allow patient tumor implantation in mice for subsequent drug testing and advanced approaches for therapy mediated by preclinical imaging. In particular we discuss targeted therapy mediated by high frequency ultrasound and magnetic resonance, two emerging techniques in molecular preclinical therapy.
*** IBB - CNR ***

Department of Advanced Biomedical Science, University of Naples Federico II, Naples, Italy., Ceinge, Advanced Biotechnology, Scarl, Naples, Italy., Institute of BioStructures and BioImaging, CNR, Naples, Italy., IRCCS SDN, Naples, Italy., Department of BioMolecular Sciences, National Center for Natural Products Research, University of Mississippi, Jackson, MS, USA., Department of Radiology, University of Mississippi Medical Center, Jackson, MS, USA., Department of BioMolecular Sciences, National Center for Natural Products Research, University of Mississippi, Jackson, MS, USA - pclaudio@olemiss.edu., Department of Radiation Oncology, Medical Center Cancer Institute, Jackson, MS, USA.,
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Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
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Auletta L, Gramanzini M, Gargiulo S, Albanese S, Salvatore M, Greco A
* Advances in multimodal molecular imaging (103 visite)
Q J Nucl Med Mol Imaging, 2017; N/D: N/D-N/D.
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Iommelli F, De Rosa V, Terlizzi C, Del Vecchio S
* Preclinical imaging in oncology: advances and perspectives (83 visite)
Q J Nucl Med Mol Imaging (ISSN: 1827-1936electronic, 1824-4785linking), 2016 Nov 18; 61(1): 33-47.
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Mainenti PP, Romano F, Pizzuti L, Segreto S, Storto G, Mannelli L, Imbriaco M, Camera L, Maurea S
* Non-invasive diagnostic imaging of colorectal liver metastases (99 visite)
World J Radiol (ISSN: 1949-8470electronic, 1949-8470linking), 2015 Jul 28; 7(7): 157-169.
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Nappi C, Acampa W, Pellegrino T, Petretta M, Cuocolo A
* Beyond ultrasound: advances in multimodality cardiac imaging (88 visite)
Intern Emerg Med Internal And Emergency Medicine (ISSN: 1970-9366, 1828-0447), 2015 Feb; 10(1): 9-20.
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Milardi D, Pappalardo M
* Molecular dynamics: New advances in drug discovery (106 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2015; 91: 1-3.
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Cella L, Conson M, Pressello MC, Molinelli S, Donato V, Orecchia R, Schnaider U, Salvatore M, Pacelli R
* Hodgkin's lymphoma advanced radiation treatment techniques: balance between late effects and secondary malignant neoplasms risk (98 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 2013 Apr 15; 73(8,Suppl.1): N/D-N/D.
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Cella L, Conson M, Pressello MC, Molinelli S, Schneider U, Donato V, Orecchia R, Salvatore M, Pacelli R
* Hodgkin's lymphoma emerging radiation treatment techniques: Trade-offs between late radio-induced toxicities and secondary malignant neoplasms (118 visite)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2013 Jan 30; 8(1): 22-22.
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Maurea S, Fusari M, Imbriaco M, Camera L, Mainenti PP, Campione S, Santangelo M, Salvatore M
* Pitfalls in diagnostic imaging of cystic pancreatic masses: a case of true cystic lesion mimicking a mucinous cystadenoma (89 visite)
Jop (ISSN: 1590-8577, 1590-0857), 2012 Jan 10; 13(1): 83-86.
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Cella L, Conson M, Pacelli R, Quarantelli M
* An Automated Atlas-Based Method For Definition Of Brain Structures On Segmentated Mri In Patients With Primary Brain Neoplasms (76 visite)
Radiotherapy And Oncology (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2012; 102: N/D-N/D.
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Supuran CT, Di Fiore A, Alterio V, Monti SM, De Simone G
* Recent advances in structural studies of the carbonic anhydrase family: The crystal structure of human CA IX and CA XIII (110 visite)
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1381-6128, 1873-4286), 2010; 16(29): 3246-3254.
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Lucignani G, Cuocolo A
Recent advances in the assessment of myocardial viability (104 visite)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Nov; 36(11): 1892-1895.
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Lucignani G, Cuocolo A
Advances in quantitative assessment of myocardial blood flow and coronary reserve (89 visite)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Oct; 36(10): 1687-1692.
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Hilvo M, De Simone G, Supuran CT, Parkkila S
* Advances in the Inhibitory and Structural Investigations on Carbonic Anhydrase Isozymes XIII and XV (102 visite)
Drug Des Of Zinc Enzyme Inhibitors (ISSN: 9780-4702, 9780-470275009), 2009; N/D: 273-283.
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Tammaro V, Spiezia S, D'Angelo S, Maurea S, Ciolli G, Salvatore M
* Diagnostic Imaging Techniques for Synchronous Multiple Tumors (82 visite)
Multiple Primary Malignancies, 2009; N/D: N/D-N/D.
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Hilvo M, Innocenti A, Monti SM, De Simone G, Supuran CT, Parkkila S
* Recent advances in research on the most novel carbonic anhydrases, CA XIII and XV (105 visite)
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1381-6128, 1873-4286), 2008; 14(7): 672-678.
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Pappalardo M, Milardi D, Grasso D, La Rosa C
* Phase behaviour of polymer-grafted DPPC membranes for drug delivery systems design (83 visite)
Journal Of Thermal Analysis And Calorimetry (ISSN: 1388-6150), 2005 May; 80(2): 413-418.
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Mainenti PP, Romano L, Contegiacomo A, Romano M, Casella V, Cuccuru A, Insabato L, Salvatore M
* Rare diffuse peritoneal malignant neoplasms: CT findings in two cases (103 visite)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Nov; 28(6): 827-830.
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Esposito L, Vitagliano L, Mazzarella L
* Recent advances in atomic resolution protein crystallography (105 visite)
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2002 Apr; 9(2): 95-105.
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Maurea S, Caracò C, Castelli L, Filice S, Alfano B, Ruffolo F, Ziviello M, Salvatore M
[Magnetic resonance in the study of suprarenal neoplasms. Qualitative and quantitative analysis of signal intensity] (91 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1998 Mar; 95(3): 199-207.
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Alfano B, Brunetti A
Advances in brain imaging: A new ethical challenge (101 visite) (PDF 172 visite)
Ann Ist Super Sanita (ISSN: 0021-2571), 1997; 33(4): 483-488.
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Maurea S, Cuocolo A, Reynolds JC, Neumann RD, Salvatore M
Diagnostic imaging in patients with paragangliomas. Computer tomography, magnetic resonance and MIBG scintigraphy comparison (99 visite)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1996; 40(4): 365-371.
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Cuocolo A, Pace L, Maurea S, Nappi A, Nicolai E, Imbriaco M, Sullo P, Cardei S, Salvatore M
Morpho-functional diagnostic imaging in the assessment of viable myocardium in patients with ischemic heart disease. Correlations between myocardial perfusion and regional function of the left ventricle (91 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1995 Jun; 89(6): 870-875.
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22 Records (19 escludendo Abstract e Conferenze).
Impact factor totale: 54.703 (40.899 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 53.55 (40.172 escludendo Abstract e Conferenze).







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