Home Ricerca Sedi Chi siamo Organigramma Personale Contatti Didattica Login Documenti EN
Progetti in evidenza
INCIPIT
(Link esterno)

ISTAPCA
(1018 visite)

LightDyNAmics
(666 visite)

Fondo Europeo Pesca
(416 visite)

 INMiND
(1031 visite)

Fondazione Veronesi
(Link esterno)

Instruct-IT
(Link esterno)

Euro-BioImaging
(Link esterno)

 PRIN
(1165 visite)

 eHealthNet
(957 visite)

  Ponrec
(901 visite)

MFAG Grant
(987 visite)

MERIT
(Link esterno)


Collegamenti



A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells (34 visite)

Cimmino I, Lorenzo V, Fiory F, Doti N, Ricci S, Cabaro S, Liotti A, Vitagliano L, Longo M, Miele C, Formisano P, Beguinot F, Ruvo M, Oriente F

Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2017 May 30; N/D: N/D-N/D.

Tipo di articolo: Journal Article,

Impact factor: 5.168

Impact factor a 5 anni: 5.312


Parole chiave: Prep1, Prep1(54-72) Peptide, Ceramide, Insulin Signalling,

Url: Non disponibile.

Prep1 is a homeodomain transcription factor belonging to the TALE protein family. Its overexpression affects glucose metabolism in several tissues. In particular, in skeletal muscle tissue the interaction of Prep1 with its cofactor p160 impairs GLUT4 expression and glucose uptake.In this study, we show that ceramides (C2cer), a class of lipids antagonizing insulin signalling, increase the levels of Prep1 and p160 in a dose and time-dependent fashion in L6 cells and induce their association by 80%. We find that C2cer exposure inhibits insulin receptor, IRS1 and Akt phosphorylation and reduces insulin-stimulated glycogen content and glucose uptake by 1.3- and 2.1-fold, respectively. The synthetic Prep1(54-72) peptide, mimicking the Prep1 region involved in the interaction with p160, reduces in vitro Prep1-p160 binding in a dose-dependent way (IC50 = 0.20muM). In C2cer-treated L6 cells, 10muM Prep1(54-72) restores insulin signalling impaired by ceramide treatment. Prep1 overexpressing L6 cells display similar metabolic alterations observed in ceramide-treated L6 cells and the presence of Prep1(54-72) mitigates these events. All these findings suggest that disruption of the Prep1/p160 molecular interaction enhances insulin sensitivity impaired by ceramides in skeletal muscle cells and indicate this complex as an important target for type 2 diabetes.
*** IBB - CNR ***

Department of Translational Medicine, Federico II University of Naples and URT "Genomic of Diabetes" of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy., Institute of Biostructure and Bioimaging - National Research Council and Interuniversity Research Centre on Bioactive Peptides, Naples, Italy.,
Non disponibile.


Contiene: [X]      Estesa  

Autori: [X]   E Tipo di lavoro: [X]

E Data iniziale: Data finale: [X]   E Sede:  E    Affiliazione IBB   [Pulisci modulo]

* Conformational stabilization of a beta-hairpin through a triazole-tryptophan interaction (22 visite)
Diana D, Di Salvo C, Celentano V, De Rosa L, Romanelli A, Fattorusso R, D'Andrea LD
Org Biomol Chem (ISSN: 1477-0539electronic, 1477-0520linking), 2018 Jan 31; 16(5): 787-795.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors (22 visite)
Mercurio FA, Di Natale C, Pirone L, Iannitti R, Marasco D, Pedone EM, Palumbo R, Leone M
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2017 Dec 12; 7(1): 17474-17474.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural insights into the interaction of a monoclonal antibody and Nodal peptides by STD-NMR spectroscopy (39 visite)
Calvanese L, Foca A, Sandomenico A, Foca G, Caporale A, Doti N, Iaccarino E, Leonardi A, D'Auria G, Ruvo M, Falcigno L
Bioorg Med Chem (ISSN: 1464-3391electronic, 0968-0896linking), 2017 Oct 28; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Antitumour activity of resveratrol on human melanoma cells: a possible mechanism related to its interaction with malignant cell telomerase (60 visite)
Platella C, Guida S, Bonmassar L, Aquino A, Bonmassar E, Ravagnan G, Montesarchio D, Roviello GN, Musumeci D, Fuggetta MP
Biochim Biophys Acta (ISSN: 0006-3002print, 0006-3002linking), 2017 Aug 02; 1861(11PtA): 2843-2851.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper ion interaction with the RNase catalytic site fragment of the angiogenin protein: an experimental and theoretical investigation (34 visite) (PDF 44 visite)
Magrì A, Tabbì G, Breglia R, De Gioia L, Fantucci P, Bruschi M, Bonomo RP, La Mendola D
Dalton Trans (ISSN: 1477-9234electronic, 1477-9226linking), 2017 Jul 04; 46(26): 8524-8538.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural investigation of a C-terminal EphA2 receptor mutant: Does mutation affect the structure and interaction properties of the Sam domain? (26 visite)
Mercurio FA, Costantini S, Di Natale C, Pirone L, Guariniello S, Scognamiglio PL, Marasco D, Pedone EM, Leone M
Biochim Biophys Acta (ISSN: 0006-3002print, 0006-3002linking, 0005-2728), 2017 Jun 06; 1865(9): 1095-1104.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides (57 visite)
Brunò E, Buemi MR, Di Fiore A, De Luca L, Ferro S, Angeli A, Cirilli R, Sadutto D, Alterio V, Monti SM, Supuran CT, De Simone G, Gitto R
J Med Chem, 2017 May 25; 60: 4316-4326.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural and biochemical insights of CypA and AIF interaction (40 visite)
Farina B, Di Sorbo G, Chambery A, Caporale A, Leoni G, Russo R, Mascanzoni F, Raimondo D, Fattorusso R, Ruvo M, Doti N
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2017 Apr 25; 7(1): 1138-1138.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements (50 visite)
Buonanno M, Langella E, Zambrano N, Succoio M, Sasso E, Alterio V, Di Fiore A, Sandomenico A, Supuran CT, Scaloni A, Monti SM, De Simone G
Acs Chem Biol (ISSN: 1554-8937electronic, 1554-8929linking), 2017 Apr 19; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The interaction of heme with plakortin and a synthetic endoperoxide analogue: new insights into the heme-activated antimalarial mechanism (17 visite) (PDF 15 visite)
Persico M, Fattorusso R, Taglialatela-scafati O, Chianese G, De Paola I, Zaccaro L, Rondinelli F, Lombardo M, Quintavalla A, Trombini C, Fattorusso E, Fattorusso C, Farina B
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2017 Apr 6; 7: 45485-45485.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper-assisted interaction between amyloid-beta and prion: Ternary metal complexes with A beta N-terminus and octarepeat (26 visite)
Magrì A, Di Natale G, Rizzarelli E
Inorg Chim Acta, 2017; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Studying the Interaction of Magainin 2 and Cecropin A with E. coli Bacterial Cells Using Circular Dichroism (59 visite)
Avitabile C, D'Andrea LD, Romanelli A
Methods Mol Biol (ISSN: 1940-6029electronic, 1064-3745linking), 2017; 1548: 247-253.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Hexokinase I N-terminal based peptide prevents the VDAC1-SOD1 G93A interaction and re-establishes ALS cell viability (43 visite)
Magrì A, Belfiore R, Reina S, Tomasello MF, Di Rosa MC, Guarino F, Leggio L, De Pinto V, Messina A
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2016 Oct 10; 6: 34802-34802.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction (44 visite) (PDF 78 visite)
Birolo L, Sacchi S, Smaldone G, Molla G, Leo G, Caldinelli L, Pirone L, Eliometri P, Di Gaetano S, Orefice I, Pedone E, Pucci P, Pollegioni L
Febs J (ISSN: 1742-4658electronic, 1742-464xlinking), 2016 Sep; 283(18): 3353-3370.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme (50 visite)
Ferraro G, Pica A, Russo Krauss I, Pane F, Amoresano A, Merlino A
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2016; N/D: 1-10.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions (72 visite)
Esposito V, Pirone L, Mayol L, Pedone E, Virgilio A, Galeone A
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2016; 127: 19-22.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Inorganic Perspective of VEGF: Interactions of Cu2 + with Peptides Encompassing a Recognition Domain of the VEGF Receptor (77 visite)
Grasso G, Santoro AM, Magrì A, La Mendola D, Tomasello MF, Zimbone S, Rizzarelli E
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2016; 159: 149-158.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Long range Trp-Trp interaction initiates the folding pathway of a pro-angiogenic beta-hairpin peptide (36 visite)
Diana D, De Rosa L, Palmieri M, Russomanno A, Russo L, La Rosa C, Milardi D, Colombo G, D'Andrea LD, Fattorusso R
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2015 Nov 25; 5: 16651-16651.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion (505 visite) (PDF 128 visite)
Fontanella R, Pelagalli A, Nardelli A, D'Alterio C, Ierano C, Cerchia L, Lucarelli E, Scala S, Zannetti A
Cancer Lett (ISSN: 1872-7980electronic, 0304-3835linking), 2015 Oct 27; 370(1): 100-107.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy (62 visite)
Cipolletta E, Rusciano MR, Maione AS, Santulli G, Sorriento D, Del Giudice C, Ciccarelli M, Franco A, Crola C, Campiglia P, Sala M, Gomez-Monterrey I, De Luca N, Trimarco B, Iaccarino G, Illario M
Plos One (ISSN: 1932-6203electronic, 1932-6203linking), 2015 Jun 25; 10(6): e0130477-e0130477.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Cross-Talk Between the Octarepeat Domain and the Fifth Binding Site of Prion Protein Driven by the Interaction of Copper(II) with the N-terminus (80 visite)
Di Natale G, Turi I, Pappalardo G, Sóvágó I, Rizzarelli E
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2015 Mar 2; 21(10): 4071-4084.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction (64 visite)
Carotenuto M, de Antonellis P, Chiarolla CM, Attanasio C, Damiani V, Boffa I, Aiese N, Pedone E, Accordi B, Basso G, Navas L, Imbimbo C, Zollo M
Naunyn Schmiedebergs Arch Pharmacol (ISSN: 0028-1298), 2015 Feb; 388(2): 257-269.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis (96 visite)
Hangen E, Féraud O, Lachkar S, Mou H, Doti N, Fimia GM, Lam N-V, Zhu C, Godin I, Muller K, Chatzi A, Nuebel E, Ciccosanti F, Flamant S, Bénit P, Perfettini J-L, Sauvat A, Bennaceur-Griscelli A, Ser-Le Roux K, Gonin P, Tokatlidis K, Rustin P, Piacentini M, Ruvo M, Blomgren K, Kroemer G, Modjtahedi N
Molecular Cell (ISSN: 1097-2765, 1097-4164), 2015; 58(6): 1001-1014.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interaction of anticancer Ru(III) complexes with single stranded and duplex DNA model systems (91 visite)
Musumeci D, Rozza L, Merlino A, Paduano L, Marzo T, Massai L, Messori L, Montesarchio D
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2015; 44(31): 13914-13925.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts (61 visite)
Messori L, Marzo T, Merlino A
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Longitudinal evaluation with High Frequency Ultrasound imaging of response to CXCR4 new cyclic peptide antagonist with conventional chemotherapy in colorectal cancer mice model (93 visite)
Greco A, D'Alterio C, Auletta L, Albanese S, Napolitano M, Portella L, Santagata S, Ierano C, Brunetti A, Scala S, Zannetti A
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2015; 42: S425-S425.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam (94 visite)
Mercurio FA, Di Natale C, Pirone L, Scognamiglio PL, Marasco D, Pedone EM, Saviano M, Leone M
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2015; 16(11): 1629-1636.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin (88 visite)
Correale S, de Paola I, Morgillo CM, Federico A, Zaccaro L, Pallante P, Galeone A, Fusco A, Pedone E, Luque FJ, Catalanotti B
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2014 Nov 6; 9(11): e112082-e112082.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Complication probability models for radiation-induced heart valvular dysfunction: Do heart-lung interactions play a role? (117 visite) (PDF 84 visite)
Cella L, Palma G, Deasy JO, Oh JH, Liuzzi R, D'Avino V, Conson M, Pugliese N, Picardi M, Salvatore M, Pacelli R
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2014 Oct 31; 9(10): 11175301-11175311.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interaction between Proteins and Ir Based CO Releasing Molecules: Mechanism of Adduct Formation and CO Release (95 visite)
Petruk AA, Vergara A, Marasco D, Bikiel D, Doctorovich F, Estrin DA, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2014 Oct 6; 53(19): 10456-10462.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Circular Dichroism studies on the interactions of antimicrobial peptides with bacterial cells (117 visite)
Avitabile C, D'Andrea LD, Romanelli A
Sci Rep (ISSN: 2045-2322, 2045-2322electronic), 2014 Mar 12; 4: 4293-4293.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability (93 visite)
Merlino A, Russo Krauss I, Castellano I, Ruocco MR, Capasso A, De Vendittis E, Rossi B, Sica F
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2014 Mar; 1844(3): 632-640.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(III) compound (66 visite)
Messori L, Scaletti F, Massai L, Cinellu MA, Russo Krauss I, Di Martino G, Vergara A, Paduano L, Merlino A
Metallomics (ISSN: 1756-5901, 1756-591x, 1756-591xelectronic), 2014; 6(2): 233-236.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of gold-based drugs with proteins: the structure and stability of the adduct formed in the reaction between lysozyme and the cytotoxic gold(III) compound Auoxo3 (85 visite)
Russo Krauss I, Messori L, Cinellu MA, Marasco D, Sirignano R, Merlino A
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2014; 43(46): 17483-17488.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Zinc(II) interactions with brain-derived neurotrophic factor N-terminal peptide fragments: inorganic features and biological perspectives (106 visite)
Travaglia A, La Mendola D, Magrì A, Pietropaolo A, Nicoletti VG, Grasso G, Malgieri G, Fattorusso R, Isernia C, Rizzarelli E
Inorg Chem (ISSN: 1520-510x, 0020-1669, 1520-510xelectronic), 2013 Oct 7; 52(19): 11075-11083.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Selective alpha v beta 3 receptor peptide antagonist for therapeutic and diagnostic applications (60 visite)
Del Gatto A, Zaccaro L, Pedone C, Saviano M
Patents Official Gazette Of The United States Patent And Trademark Office (ISSN: 0098-1133), 2013 Oct 1; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A biophysical characterization of the folded domains of KCTD12: insights into interaction with the GABA(B2) receptor (85 visite)
Correale S, Esposito C, Pirone L, Vitagliano L, Di Gaetano S, Pedone E
Journal Of Molecular Recognition (ISSN: 0952-3499, 0952-2349), 2013 Oct; 26(10): 488-495.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Preclinical Development of a Novel Class of CXCR4 Antagonist Impairing Solid Tumors Growth and Metastases (97 visite)
Portella L, Vitale R, De Luca S, D'Alterio C, Ieranò C, Napolitano M, Riccio A, Polimeno MN, Monfregola L, Barbieri A, Luciano A, Ciarmiello A, Arra C, Castello G, Amodeo P, Scala S
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2013 Sep 13; 8(9): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates (105 visite)
Diana D, Smaldone G, De Antonellis P, Pirone L, Carotenuto M, Alonzi A, Di Gaetano S, Zollo M, Pedone E, Fattorusso R
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Sep 9; 19(37): 12217-12220.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Molecular basis of the PED/PEA15 interaction with the C-terminal fragment of phospholipase D1 revealed by NMR spectroscopy (116 visite)
Farina B, Doti N, Pirone L, Malgieri G, Pedone E, Ruvo M, Fattorusso R
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Sep; 1834(8): 1572-1580.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Peptide-Lipid Interactions: Experiments and Applications (92 visite)
Galdiero S, Falanga A, Cantisani M, Vitiello M, Morelli G, Galdiero M
Int J Mol Sci (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2013 Sep; 14(9): 18758-18789.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu (87 visite)
Vergara A, D’Errico G, Montesarchio D, Mangiapia G, Paduano L, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Apr 15; 52(8): 4157-4159.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural investigation of the VEGF receptor interaction with a helical antagonist peptide (101 visite)
Diana D, Di Stasi R, De Rosa L, Isernia C, D'Andrea LD, Fattorusso R
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 214-219.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction (176 visite)
Carotenuto M, Pedone E, Diana D, de Antonellis P, Džeroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M
Sci Rep (ISSN: 2045-2322, 2045-2322electronic), 2013 Mar 1; 3: 1351-1351.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* In vitro activity of the alphavbeta3 integrin antagonist RGDechi-hCit on malignant melanoma cells (66 visite)
Pisano M, De Paola I, Nieddu V, Sassu I, Cossu S, Galleri G, Del Gatto A, Budroni M, Cossu A, Saviano M, Palmieri G, Zaccaro L, Rozzo C
Anticancer Res (ISSN: 0250-7005, 0250-0700, 1791-7530electronic), 2013 Mar; 33(3): 871-879.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Plasmonics for the study of metal ion-protein interactions (73 visite)
Grasso G, Spoto G
Analytical And Bioanalytical Chemistry (ISSN: 1618-2642), 2013 Feb; 405(6): 1833-1843.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Role of mutual interactions in the chemical and thermal stability of nucleophosmin NPM1 domains (67 visite)
Marasco D, Ruggiero A, Vascotto C, Poletto M, Scognamiglio PL, Tell G, Vitagliano L
Biochemical And Biophysical Research Communications (ISSN: 0006-291x), 2013 Jan 11; 430(2): 523-528.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Electrostatically driven interaction of silica-supported lipid bilayer nanoplatforms and a nerve growth factor-mimicking peptide (79 visite)
Travaglia A, Satriano C, Giuffrida ML, La Mendola D, Rampazzo E, Prodi L, Rizzarelli E
Soft Matter (ISSN: 1744-683x), 2013; 9(18): 4648-4654.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Insights Into The Mechanism Of Interaction Between Trehalose-Conjugated Beta-Sheet Breaker Peptides And Aβ(1-42) Fibrils By Molecular Dynamics Simulations (89 visite)
Autiero I, Langella E, Saviano M
Molecular Biosystems (ISSN: 1742-206x, 1742-2206), 2013; 9(11): 2835-2841.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Role Of The Unstructured N-Terminal Domain Of The Human Apurinic/Apyrimidinic Endonuclease 1 (hape1) In The Modulation Of Its Interaction With Nucleic Acids And Nucleophosmin (npm1) (94 visite)
Poletto M, Vascotto C, Scognamiglio PL, Lirussi L, Marasco D, Tell G
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2013; 452(3): 545-557.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Microbe-Host Interactions: Structure and Role of Gram-Negative Bacterial Porins (84 visite)
Galdiero S, Falanga A, Cantisani M, Tarallo R, della Pepa ME, D'Oriano V, Galdiero M
Curr Protein Pept Sci (ISSN: 1389-2037), 2012 Dec; 13(8): 843-854.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells (123 visite)
Accardo A, Mansi R, Salzano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Ziaco B, Tesauro D, Aloj L, De Rosa G, Morelli G
Journal Of Drug Targeting (ISSN: 1061-186x), 2012 Nov 21; 21(3): 240-249.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Combined Imaging with 18F-FLT PET/CT and 99m-Tc-Hynic-Annexin V SPECT for Personalized Therapy with EGFR Antagonists and Bcl-xL Inhibitors in Non-Small Cell Lung Cancer (73 visite)
Zannetti A, Iommelli F, De Rosa V, Nardelli A, Ortosecco G, Del Vecchio S
European Journal Of Cancer (ISSN: 0959-8049), 2012 Nov; 48: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of Cu 2+ with prion family peptide fragments: Considerations on affinity, speciation and coordination (89 visite)
Arena G, La Mendola D, Pappalardo G, Sovago I, Rizzarelli E
Coordination Chemistry Reviews (ISSN: 0010-8545), 2012 Oct; 256(19-20): 2202-2218.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Small animal SPECT with 99m-Tc-Hynic-annexin V for detection of non-small cell lung cancer resistance to EGFR antagonists and its reversal by Bcl-xL inhibitors (78 visite)
Zannetti A, Iommelli F, De Rosa V, Salvatore M, Del Vecchio S
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Oct; 39: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) interaction with peptide fragments of histidine-proline-rich glycoprotein: Speciation, stability and binding details (83 visite)
La Mendola D, Magrì A, Santoro AM, Nicoletti VG, Rizzarelli E
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Jun; 111: 59-69.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of two O-phosphorylresveratrol derivatives with model membranes (56 visite)
Sciacca MF, Chillemi R, Sciuto S, Pappalardo M, La Rosa C, Grasso D, Milardi D
Arch Biochem Biophys (ISSN: 1096-0384, 0003-3986), 2012 May; 521(1-2): 111-116.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination (93 visite)
Esposito C, Cantisani M, D'Auria G, Falcigno L, Pedone E, Galdiero S, Berisio R
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2012 Mar 23; 586(6): 659-667.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* 3'-deoxy-3'-18F-fluorothymidine (FLT) PET/CT to guide therapy with epidermal growth factor receptor (EGFR) antagonists and Bcl-xL inhibitors in non-small cell lung cancer (187 visite)
Zannetti A, Iommelli F, Speranza A, Salvatore M, Del Vecchio S
Journal Of Nuclear Medicine (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2012 Mar 1; 53(3): 443-450.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* 3'-deoxy-3'-18F-fluorothymidine PET/CT to guide therapy with epidermal growth factor receptor antagonists and Bcl-xL inhibitors in non-small cell lung cancer (123 visite)
Zannetti A, Iommelli F, Speranza A, Salvatore M, Del Vecchio S
Journal Of Nuclear Medicine (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2012 Mar 1; 53(3): 443-450.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Biophysical Characterization and Membrane Interaction of the Two Fusion Loops of Glycoprotein B from Herpes Simplex Type I Virus (139 visite)
Falanga A, Tarallo R, Vitiello G, Vitiello M, Perillo E, Cantisani M, D'Errico G, Galdiero M, Galdiero S
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2012 Feb 23; 7(2): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(ii) Interaction With Amyloid-Beta: Affinity And Speciation (96 visite)
Arena G, Pappalardo G, Sovago I, Rizzarelli E
Coordination Chemistry Reviews (ISSN: 0010-8545), 2012 Jan; 256(1-2): 3-12.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease (72 visite)
D'Errico G, Ercole C, Lista M, Pizzo E, Falanga A, Galdiero S, Spadaccini R, Picone D
Biochim Biophys Acta (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Dec; 1808(12): 3007-3015.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Lipid composition modulates the interaction of peptides deriving from herpes simplex virus type I glycoproteins B and H with biomembranes (86 visite)
Vitiello G, Falanga A, Galdiero M, Marsh D, Galdiero S, D'Errico G
Biochim Biophys Acta (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Oct; 1808(10): 2517-2526.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Intramolecular weak interactions in the thermodynamic stereoselectivity of copper(II) complexes with carnosine-trehalose conjugates (97 visite)
Grasso GI, Arena G, Bellia F, Maccarrone G, Parrinello M, Pietropaolo A, Vecchio G, Rizzarelli E
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Sep 16; 17(34): 9448-9455.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural and functional insights into IkappaB-alpha/HIV-1 Tat interaction (102 visite)
Vitagliano L, Fiume G, Scognamiglio PL, Doti N, Cannavo R, Puca A, Pedone C, Scala G, Quinto I, Marasco D
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2011 Sep; 93(9): 1592-1600.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Noncovalent interaction-driven stereoselectivity of copper(II) complexes with cyclodextrin derivatives of L- and D-carnosine (89 visite)
Grasso GI, Bellia F, Arena G, Vecchio G, Rizzarelli E
Inorg Chem (ISSN: 1520-510x, 0020-1669, 1520-510xelectronic), 2011 Jun 6; 50(11): 4917-4924.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Branched peptides for the modulation of protein-protein interactions: More arms are better than one? (116 visite)
Ruvo M, Sandomenico A, Tudisco L, De Falco S
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2011 Jun; 18(16): 2429-2437.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (124 visite)
Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2011 May; 77(5): 319-327.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The inorganic perspective of nerve growth factor: interactions of Cu2+ and Zn2+ with the N-terminus fragment of nerve growth factor encompassing the recognition domain of the TrkA receptor (87 visite)
Travaglia A, Arena G, Fattorusso R, Isernia C, La Mendola D, Malgieri G, Nicoletti VG, Rizzarelli E
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Mar 21; 17(13): 3726-3738.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo (92 visite)
Basile A, Del Gatto A, Diana D, Di Stasi R, Falco A, Festa M, Rosati A, Barbieri A, Franco R, Arra C, Pedone C, Fattorusso R, Turco MC, D'Andrea LD
J Med Chem (ISSN: 1520-4804, 0022-2623, 0022-2623print), 2011 Mar 10; 54(5): 1391-1400.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Evaluation of the anti-angiogenic properties of the new selective alphaVbeta3 integrin antagonist RGDechiHCit (76 visite)
Santulli G, Basilicata MF, De Simone M, Del Giudice C, Anastasio A, Sorriento D, Saviano M, Del Gatto A, Trimarco B, Pedone C, Zaccaro L, Iaccarino G
J Transl Med Journal Of Translational Medicine (ISSN: 1479-5876electronic), 2011 Jan 13; 9: 7-7.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Role Of Aromatic Side-Chains In Amyloid Growth And Membrane Interaction Of The Islet Amyloid Polypeptide Fragment Lanflvh (95 visite)
Milardi D, Sciacca MFM, Pappalardo M, Grasso DM, La Rosa C
Eur Biophys J, 2011 Jan; 40(1): 1-12.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Membrane interactions and conformational preferences of human and avian prion N-terminal tandem repeats: The role of copper(II) ions, pH, and membrane mimicking environments (105 visite)
Di Natale G, Pappalardo G, Milardi D, Sciacca MF, Attanasio F, La Mendola D, Rizzarelli E
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 Nov 4; 114(43): 13830-13838.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Residues 762-801 of PLD1 mediate the interaction with PED/PEA15 (69 visite)
Doti N, Cassese A, Marasco D, Paturzo F, Sabatella M, Viparelli F, Dathan N, Monti SM, Miele C, Formisano P, Beguinot F, Ruvo M
Mol Biosyst (ISSN: 1742-206x), 2010 Oct; 6(10): 2039-2048.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Gamma-Hydroxymethyl Pnas: Synthesis, Interaction With Dna And Inhibition Of Protein/Dna Interactions (75 visite)
Pensato S, Saviano M, Bianchi N, Borgatti M, Fabbri E, Gambari R, Romanelli A
Bioorg Chem, 2010 Sep; 38(5): 196-201.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (69 visite)
Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Carbonic anhydrase inhibitors: Crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV (70 visite)
Di Fiore A, Monti SM, Innocenti A, Winum J-Y, De Simone G, Supuran CT
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2010 Jun 15; 20(12): 3601-3605.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Biochemical and Structural Analysis of the Binding Determinants of a Vascular Endothelial Growth Factor Receptor Peptidic Antagonist (64 visite)
Gautier B, Goncalves V, Diana D, Di Stasi R, Teillet F, Lenoir C, Huguenot F, Garbay C, Fattorusso R, D'Andrea LD, Vidal M, Inguimbert N
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jun 10; 53(11): 4428-4440.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A doppel alpha-helix peptide fragment mimics the copper(II) interactions with the whole protein (296 visite)
La Mendola D, Magrì A, Campagna T, Campitiello MA, Raiola L, Isernia C, Hansson O, Bonomo RP, Rizzarelli E
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2010 Jun 1; 16(21): 6212-6223.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis and Characterization of a Selective Alpha(v)Beta(3) Receptor Cyclic Peptide Antagonist Functionalized with a Chelating Group for Metal Labelling (65 visite)
Monfregola L, Saviano M, De Luca S
International Journal Of Peptide Research And Therapeutics (ISSN: 1573-3149, 0929-5666), 2010 Mar; 16(1): 1-5.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Different Interactions Of Human And Avian Prion Proteins N-Terminal Tandem Repeat Peptides And Their Copper (ii) Complexes With Model Membranes (65 visite)
Di Natale G, Pappalardo G, Milardi D, Sciacca MFM, Attanasio F, La Mendola D, Rizzarelli E
Journal Of Chemical Physics, 2010; 114: 13830-13838.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells (77 visite)
Farina AR, Tacconelli A, Cappabianca L, Cea G, Chioda A, Romanelli A, Pensato S, Pedone C, Gulino A, Mackay AR
Oncogene (ISSN: 1476-5594, 0950-9232), 2009 Nov 19; 28(46): 4075-4094.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Interaction Of Copper (ii) With The Prion Peptide Fragment Huprp (76-114) Encompassing Four Histidyl Residues Within And Outside The Octarepeat Domain (84 visite)
Di Natale G, Osz K, Nagy Z, Sanna D, Micera G, Pappalardo G, Sovago I, Rizzarelli E
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2009 May 4; 48(9): 4239-4250.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists (87 visite)
Sandomenico A, Monti SM, Sabatella M, De Capua A, Tornatore L, Doti N, Viparelli F, Dathan NA, Pedone C, Ruvo M, Marasco D
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0285, 1747-0277), 2009 May; 73(5): 483-493.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor (74 visite)
Calvanese L, Saporito A, Oliva R, D'Auria G, Pedone C, Paolillo L, Ruvo M, Marasco D, Falcigno L
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 175-183.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A mass spectrometry and surface enhanced Raman spectroscopy study of the interaction between linear carbon chains and noble metals (96 visite)
Grasso G, D'Urso L, Messina E, Cataldo F, Puglisi O, Spoto G, Compagnini G
Carbon (ISSN: 0008-6223), 2009; 47(11): 2611-2619.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A new and selective radiolabeled alpha(V)beta(3) peptide antagonist as tracer in tumor diagnosis (75 visite)
De Luca S, Del Gatto A, Ruvo M, Panico M, Zannetti A, Del Vecchio S, Salvatore M, Pedone C, Saviano M, Zaccaro L
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print), 2009; 611: 439-440.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interaction of human amylin with phosphatidylcholine and phosphatidylserine membranes (71 visite)
Sciacca MFM, Carbone V, Pappalardo M, Milardi D, La Rosa C, Grasso DM
Mol Cryst Liq Cryst (ISSN: 1542-1406), 2009; 500: 73-81.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interaction Of Human Amylin With Phosphatidylcholine And Phosphatydylserine Membranes (66 visite)
Sciacca MFM, Carbone V, Pappalardo M, Milardi D, La Rosa C, Grasso DM
Mol Cryst Liq Cryst, 2009; 500: 73-81.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of Λ and Δ enantiomers of ruthenium(II) cationic complexes with achiral anionic porphyrins (75 visite)
Randazzo R, Lauceri R, Mammana A, D'Urso A, Purrello R
Chirality (ISSN: 0899-0042), 2009; 21(1): 92-96.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Peptide antagonists of the PED-hPLD1 binding (63 visite)
Viparelli F, Doti N, Monti SM, Marasco D, Dathan N, Pedone C, Miele C, Formisano P, Beguinot F, Ruvo M
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print, 0065-2598linking), 2009; 611: 445-446.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders (60 visite)
Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2008 Dec; 33(12): 2401-2406.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Calcium-Activated Membrane Interaction Of The Islet Amyloid Polypeptide: Implications In The Pathogenesis Of Type Ii Diabetes Mellitus (92 visite)
Sciacca MFM, Pappalardo M, Milardi D, Grasso DM, La Rosa C
Arch Biochem Biophys, 2008 Sep 15; 65(1-2): 291-298.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Kinetic investigation of porphyrin interaction with chiral templates reveals unexpected features of the induction and self-propagation mechanism of chiral memory (71 visite)
Lauceri R, Fasciglione G, D'Urso A, Marini S, Purrello R, Coletta M
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2008 Sep 13; 130(32): 10476-10477.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Studies of nitric oxide interaction with mono- and dinuclear copper(II) complexes of prion protein bis-octarepeat fragments (110 visite)
Bonomo RP, Pappalardo G, Rizzarelli E, Tabbì G, Vagliasindi LI
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2008 Sep 7; (29): 3805-3816.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells (77 visite)
Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2008 Sep 1; 283(31): 21769-21778.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* An analysis of deletion mutants of the PLD1 D4 domain defines short regions within the PLD1 interacting with PED/PEA15: implications for the development of peptides-specific antagonist (67 visite)
Doti N, Marasco D, Sabatella M, Monti SM, Dathan N, Viparelli F, Cassese A, Miele C, Pedone C, Ruvo M
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Metal ion interactions within the 1-16 N-terminal region of beta-amyloid (73 visite)
Damante C, Osz K, Nagy Z, Pappalardo G, Grasso G, Impellizzeri G, Rizzarelli E, Sovago I
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Peptide antagonists of protein-protein interactions identified by screening protein fragments derived by enzyme degradation (57 visite)
Ruvo M, Marasco D, Viparelli F, Tornatore L, Sandomenico A, Doti N, Pedone C, Benedetti E, Monti SM
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Insights into cytochrome c-cardiolipin interaction. Role played by ionic strength (91 visite)
Sinibaldi F, Fiorucci L, Patriarca A, Lauceri R, Ferri T, Coletta M, Santucci R
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2008 Jul 1; 47(26): 6928-6935.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15 (62 visite)
Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
Protein Expr Purif (ISSN: 1046-5928), 2008 Jun; 59(2): 302-308.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Contribution of dipole-dipole interactions to the stability of the collagen triple helix (60 visite)
Improta R, Berisio R, Vitagliano L
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2008 May; 17(5): 955-961.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* An urokinase receptor antagonist that inhibits cell migration by blocking the formyl peptide receptor (45 visite)
Bifulco K, Longanesi-cattani I, Gargiulo L, Maglio O, Cataldi M, De Rosa M, Stoppelli MP, Pavone V, Carriero MV
Febs Lett (ISSN: 0014-5793print, 0014-5793linking, 1873-3468electronic), 2008 Apr 2; 582(7): 1141-1146.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Preparation and use of cyclic and branched peptides and their labelled derivatives as therapeutic agents, cholecystokinin agonists or antagonists, and diagnostic agents to identify and locate tumours (66 visite)
Saviano M, De Luca S, Morelli G, Tesauro D, Pedone C
Patents Official Gazette Of The United States Patent And Trademark Office (ISSN: 0098-1133), 2008 Feb 12; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* AP/MALDI-MS complete characterization of the proteolytic fragments produced by the interaction of insulin degrading enzyme with bovine insulin (104 visite)
Grasso G, Rizzarelli E, Spoto G
J Mass Spectrom Journal Of Mass Spectrometry (ISSN: 1076-5174, 1096-9888), 2007 Dec; 42(12): 1590-1598.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Carnosine interaction with nitric oxide and astroglial cell protection (215 visite)
Nicoletti VG, Santoro AM, Grasso G, Vagliasindi LI, Giuffrida ML, Cuppari C, Purrello VS, Stella AMG, Rizzarelli E
Journal Of Neuroscience Research (ISSN: 0360-4012), 2007 Sep 1; 85(10): 2239-2245.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Nitrogen oxide interaction with copper complexes formed by small peptides belonging to the prion protein octa-repeat region (83 visite)
Bonomo RP, Pappalardo G, Rizzarelli E, Santoro AM, Tabbì G, Vagliasindi LI
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2007 Apr 14; (14): 1400-1408.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Does Tetracycline Bind Helix 2 Of Prion? An Integrated Spectroscopical And Computational Study Of The Interaction Between The Antibiotic And Alpha Helix 2 Human Prion Protein Fragments (116 visite)
Ronga L, Langella E, Palladino P, Marasco D, Tizzano B, Saviano M, Pedone C, Improta R, Ruvo M
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Feb 15; 66(3): 707-715.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Beta-Barrel Membrane Bacterial Proteins: Structure, Function, Assembly And Interaction With Lipids (69 visite)
Galdiero S, Galdiero M, Pedone C
Curr Protein Pept Sci (ISSN: 1389-2037), 2007 Feb; 8(1): 63-82.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Fate of prions in soil: Interaction of a recombinant ovine prion protein with synthetic humic-like mineral complexes (62 visite)
Rao M, Russo F, Granata V, Berisio R, Zagari A, Gianfreda L
Soil Biol Biochem (ISSN: 0038-0717), 2007 Feb; 39(2): 493-504.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A new and selective radiolabeled alpha(v)beta 3 peptide antagonist as tracer in tumor diagnosis (64 visite)
Zaccaro L, Del Gatto A,  De Luca S, Ruvo M, Zannetti A, Del Vecchio S, Salvatore M, Pedone C, Saviano M
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(4): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) interaction with prion peptide fragments encompassing histidine residues within and outside the octarepeat domain: speciation, stability constants and binding details (82 visite)
Osz K, Nagy Z, Pappalardo G, Di Natale G, Sanna D, Micera G, Rizzarelli E, Sóvágó I
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2007; 13(25): 7129-7143.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Environmental factors differently affect human and rat IAPP: Conformational preferences and membrane interactions of IAPP17-29 peptide derivatives (112 visite)
Pappalardo G, Milardi D, Magrì A, Attanasio F, Impellizzeri G, La Rosa C, Grasso D, Rizzarelli E
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2007; 13(36): 10204-10215.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Modelling IAPP's membrane interaction: Conformational preferences and membrane activity of IAPP17-29 peptide derivatives (75 visite)
Pappalardo G, Milardi D, Magna A, Attanasio F, Impellizzeri G, La Rosa C, Grasso D, Rizzarelli E
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(4): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX (84 visite)
Alterio V, Vitale RM, Monti SM, Pedone C, Scozzafava A, Cecchi A, De Simone G, Supuran CT
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2006 Jun 28; 128(25): 8329-8335.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Novel And Selective Alpha (v) Beta3 Receptor Peptide Antagonist: Design, Synthesis, And Biological Behavior (133 visite)
Del Gatto A, Zaccaro L, Grieco P, Novellino E, Zannetti A, Del Vecchio S, Iommelli F, Salvatore M, Pedone C, Saviano M
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Jun 1; 49(11): 3416-3420.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Anthranilic acid based CCK1 receptor antagonists and CCK-8 have a common step in their "receptor desmodynamic processes" (112 visite)
De Luca S, Saviano M, Lassiani L, Yannakopoulou K, Stefanidou P, Aloj L, Morelli G, Varnavas A
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Apr 20; 49(8): 2456-2462.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Novel and selective alpha v beta 3 receptor peptide antagonist: Design, synthesis and biological behaviour (75 visite)
Del Gatto A, Zaccaro L, Zannetti A, Del Vecchio S, Benedetti E, Salvatore M, Pedone C, Saviano M
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006; 12: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Environmental effects on a prion's helix II domain: copper(II) and membrane interactions with PrP180-193 and its analogues (70 visite)
Grasso D, Grasso G, Guantieri V, Impellizzeri G, La Rosa C, Milardi D, Micera G, Osz K, Pappalardo G, Rizzarelli E, Sanna D, Sovago I
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2005 Dec 23; 12(2): 537-547.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex (71 visite)
Santelli E, Leone M, Li C, Fukushima T, Preece NE, Olson AJ, Ely KR, Reed JC, Pellecchia M, Liddington RC, Matsuzawa S-I
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2005 Oct 7; 280(40): 34278-34287.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) interaction with unstructured prion domain outside the octarepeat region: Speciation, stability, and binding details of copper(II) complexes with PrP106-126 peptides (85 visite)
Di Natale G, Grasso G, Impellizzeri G, La Mendola D, Micera G, Mihala N, Nagy Z, Osz K, Pappalardo G, Rigó V, Rizzarelli E, Sanna D, Sóvágó I
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2005 Oct 3; 44(20): 7214-7225.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor (56 visite)
Naddeo M, Vitagliano L, Russo A, Gotte G, D'Alessio G, Sorrentino S
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2005 May 9; 579(12): 2663-2668.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* High Resolution Crystallographic Studies Of Alpha-Hemolysin-Phospholipid Complexes Define Heptamer-Lipid Head Group Interactions: Implication For Understanding Protein-Lipid Interactions (75 visite)
Galdiero S, Gouaux E
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2004 Jun; 13(6): 1503-1511.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The different role of Cu++ and Zn++ ions in affecting the interaction of prion peptide PrP106-126 with model membranes (71 visite)
Grasso D, Milardi D, La Rosa C, Rizzarelli E
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2004 Jan 21; 10(2): 246-247.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A Spectroscopic Investigation Of The Interaction Between Nitrogen Monoxide And Copper Sites Of The Fungal Laccase From Rigidoporus Lignosus (42 visite)
Bonomo RP, Castronovo BM, Santoro AM
Dalton Trans, 2004 Jan 7; N/D: 104-112.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Assesing the reliability of density functional methods in the conformational study of polypeptides: The treatment of intraresidue nonbonding interactions (56 visite)
Improta R, Barone V
J Comput Chem (ISSN: 0192-8651, 1096-987xelectronic), 2004; 25(11): 1333-1341.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Development of peptides able to modulate the interaction of AKAP121 with mitochondria (63 visite)
Saviano M, Zaccaro L, Benedetti E, Pedone C, Del Gatto A, Feliciello A, Affaiatati A, Avvedimento EV
Peptide Revolution, 2004; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Structure of the Stemloop D Subdomain of Coxsackievirus B3 Cloverleaf RNA and Its Interaction with the Proteinase 3C (84 visite)
Ohlenschlager O, Wohnert J, Bucci E, Seitz S, Hafner S, Ramachandran R, Zell R, Gorlach M
Structurestructure (ISSN: 0969-2126, 1878-4186), 2004; 12(2): 237-248.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Hyaluronate tetrasaccharide-Cu(II) interaction: A NMR study (76 visite)
D'Auria G, Flores G, Falcigno L, Oliva R, Vacatello M, Corsaro MM, Parrilli M, Paolillo L
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003 Oct; 70(2): 260-269.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A simplified model of the binding interaction between stromal cell-derived factor-1 chemokine and CXC chemokine receptor (86 visite)
Palladino P, Pedone C, Ragone R, Rossi F, Saviano M, Benedetti E
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2003 Apr; 10(2): 133-138.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A simplified model of the interaction between SDF-1 chemokine and the CXCR4 receptor (76 visite)
Palladino P, De Capua A, Pedone C, Ragone R, Rossi F, Limatola C, Ragozzino D, Benedetti E
Peptide Revolution, 2003 Apr; 10(2): 133-138.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthetic peptides mimicking the interleukin-6/gp130 interaction: a two-helix bundle system. Design and conformational studies (74 visite)
Zaccaro L, Bucci E, Vitale RM, Perretta G, Fattorusso R, Benedetti E, Saviano M, Pedone C
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2003 Feb; 9(2): 105-105.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Functional Mimics Of Cu, Zn-Superoxide Dismutase Enzymes, In Metal-Ligand Interactions In Nano-, Micro-, And Macro-Systems In Complex Environments (60 visite)
Bonomo RP, Impellizzeri G, La Mendola D, Maccarone G, Pappalardo G, Santoro A, Tabbì G, Vecchio G, Rizzarelli E
In Complex Environmentsmetal Ligand Interactions (ISSN: 1568-2609, 1568-8260), 2003 Jan; 116: 41-63.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interaction of prion peptide PrP 180-193 with DPPC model membranes: A thermodynamic study (95 visite)
Grasso D, Milardi D, Guantieri V, La Rosa C, Rizzarelli E
New Journal Of Chemistry (ISSN: 1144-0546), 2003; 27(2): 359-364.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthetic peptides mimicking the interleukin-6/gp130 interaction: A two-helix bundle system. Design and confirmational studies (73 visite)
Zaccaro L, Bucci E, Vitale RM, Perretta G, Fattorusso R, Benedetti E, Saviano M, Pedone C
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2003; 9(2): 90-105.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The interaction of a peptide with a scrambled hydrophobic/hydrophilic sequence (Pro-Asp-Ala-Asp-Ala-His-Ala-His-Ala-His-Ala-Ala-Ala-His-Gly) (PADH) with DPPC model membranes: A DSC study (79 visite)
Grasso D, Milardi D, La Rosa C, Impellizzeri G, Pappalardo G
Thermochim Acta (ISSN: 0040-6031), 2002 Jul 15; 390(1-2): 73-78.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Molecular interactions between nuclear factor κB (NF-κB) transcription factors and a PNA-DNA chimera mimicking NF-κB binding sites (71 visite)
Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
European Journal Of Biochemistry (ISSN: 0014-2956), 2001 Dec; 268(23): 6066-6075.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites (64 visite)
Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
Eur J Biochem (ISSN: 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of anionic carboranylated porphyrins with DNA [3] (67 visite)
Lauceri R, Purrello R, Shetty SJ, Vicente MGH
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2001 Jun 20; 123(24): 5835-5836.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* DSC study of the interaction of the prion peptide PrP106-126 with artificial membranes (73 visite)
Grasso D, Milardi D, La Rosa C, Rizzarelli E
New Journal Of Chemistry (ISSN: 1144-0546), 2001; 25(12): 1543-1548.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Specific interaction between bovine cyclophilin A and synthetic analogues of cyclolinopeptide (70 visite)
Gallo P, Rossi F, Saviano M, Pedone C, Colonna G, Ragone R
Journal Of Biochemistry (ISSN: 0021-924x), 1998 Nov; 124(5): 880-885.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Neuronorm is a potent and water soluble neurokinin A receptor antagonist (50 visite)
Lombardi A, D'Agostino B, Filippelli A, Pedone C, Matera MG, Falciani M, De Rosa M, Rossi F, Pavone V
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 1998 Jul 7; 8(13): 1735-1740.
Dettagli    Esporta in BibTeX    Esporta in EndNote

A novel super-potent neurokinin A receptor antagonist containing dehydroalanine (69 visite)
Lombardi A, D'Agostino B, Nastri F, D'Andrea LD, Filippelli A, Falciani M, Rossi F, Pavone V
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894xprint, 0960-894xlinking), 1998 May 19; 8(10): 1153-1156.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Synthesis, spectroscopic characterisation, and metal ion interaction of a new α-helical peptide (76 visite)
Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E, Santoro AM
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1998; 4(9): 1791-1798.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Experimental evidence at atomic resolution for intramolecular N- H···π (phenyl) interactions in a family of amino acid derivatives (72 visite)
Crisma M, Formaggio F, Valle G, Toniolo C, Saviano M, Iacovino R, Zaccaro L, Benedetti E
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1997; 42(1): 1-6.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Structure Of Copper(ii) Complexes With L-Leucyl-D-Phenylalanine Or L-Leucyl-L-Phenylalanine And Lcao-Scf-Mo Calculations On The Stabilization Of Copper(ii) Complexes Due To D-π Interaction With Aromatic Ring (69 visite)
Maccarrone G, Nardin G, Randaccio L, Tabbì G, Rosi M, Sgamellotti A, Rizzarelli E, Zangrando E
Dalton Trans, 1996; N/D: 3449-3453.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Study of H2O2 interaction with copper(II) complexes with diamino-diamide type ligands, diastereoisomeric dipeptides, and tripeptides (64 visite)
Bonomo RP, Marchelli R, Tabbì G
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Nov 15; 60(3): 205-218.
Dettagli    Esporta in BibTeX    Esporta in EndNote

SPECIFIC INTERACTION BETWEEN CYCLOPHILIN AND CYCLIC-PEPTIDES (75 visite)
Gallo P, Saviano M, Rossi F, Pavone V, Pedone C, Ragone R, Stiuso P, Colonna G
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1995 Sep; 36(3): 273-281.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Design and structure of a novel Neurokinin A receptor antagonist cyclo(-Met1-Asp2-Trp3-Phe4-Dap 5-Leu6-)cyclo(2β-5β) (68 visite)
Pavone V, Lombardi A, Nastri F, Saviano M, Maglio O, D'Auria G, Quartara L, Maggi CA, Pedone C
(ISSN: 1472-779x), 1995; (5): 987-993.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Interaction of water-soluble porphyrins with single- and double-stranded polyribonucleotides (57 visite)
Bustamante C, Gurrieri S, Pasternack RF, Purrello R, Rizzarelli E
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1994 Sep; 34(8): 1099-1104.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Structural requirements for antagonist activity at tachykinin NK2 receptor in a series of bicyclic hexapeptides (39 visite)
L , Q , Fabbri G, Patacchini R, A , Maggi C, Astolfi M, D'Auria G, Maglio O, Lombardi A, Pedone C, Pavone V
Peptides, 1994; N/D: 591-592.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Non-Covalent Interactions in Cyclopeptide Proton Complex Formation in Aqueous Solution (55 visite)
Arena G, Impellizzeri G, Maccarrone G, Pappalardo G, Sciotto D, Rizzarelli E
Thermochim Acta, 1989; 154: 97-106.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Study With The Competitive 5 Ht2 Receptor Antagonist Ketanserin (49 visite)
Ferrara LA, Fasano ML, Rubba P, Soro S, Marotta G, Mancini M
Journal Of Cardiovascular Pharmacology, 1985; 7: 159-160.
Dettagli    Esporta in BibTeX    Esporta in EndNote



154 Records (139 escludendo Abstract e Conferenze).
Impact factor totale: 556.512 (513.184 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 585.594 (539.044 escludendo Abstract e Conferenze).

Interrogazione bibliografica effettuata: (([btitle] "Prep1(54-72) Peptide" OR [btitle] "Ceramide" OR [btitle] "Insulin Signalling" OR [btitle] "antagonist" OR [btitle] "interaction") AND NOT [id] = 53569)







    Esporta in BibTeX    Esporta in EndNote

Ultima modifica di Gennaro Angrisano in data Monday 24 July 2017, 13:30:02
34 visite. Ultima visita in data Wednesday 06 June 2018, 1:39:17

Webmaster and developer: Marco Comerci
Per problemi e suggerimenti: adminibb.cnr.it
Ultimo aggiornamento: Tuesday 19 June 2018, 17:57:13