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Microgel assisted Lab-on-Fiber Optrode (311 visite) (PDF pubblico 98 visite)

Aliberti A, Ricciardi A, Giaquinto M, Micco A, Bobeico E, La Ferrara V, Ruvo M, Cutolo A, Cusano A

Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2017 Oct 31; 7(1): 14459-14459.

Tipo di articolo: Journal Article

Impact factor: 4.259

Impact factor a 5 anni: 4.847


Parole chiave: Optrode, Microgel Assisted, Lab On Fiber

Url: Non disponibile.

Precision medicine is continuously demanding for novel point of care systems, potentially exploitable also for in-vivo analysis. Biosensing probes based on Lab-On-Fiber Technology have been recently developed to meet these challenges. However, devices exploiting standard label-free approaches (based on ligand/target molecule interaction) suffer from low sensitivity in all cases where the detection of small molecules at low concentrations is needed. Here we report on a platform developed through the combination of Lab-On-Fiber probes with microgels, which are directly integrated onto the resonant plasmonic nanostructure realized on the fiber tip. In response to binding events, the microgel network concentrates the target molecule and amplifies the optical response, leading to remarkable sensitivity enhancement. Moreover, by acting on the microgel degrees of freedom such as concentration and operating temperature, it is possible to control the limit of detection, tune the working range as well as the response time of the probe. These unique characteristics pave the way for advanced label-free biosensing platforms, suitably reconfigurable depending on the specific application.
*** IBB - CNR ***

Optoelectronics Group, Department of Engineering, University of Sannio, I-82100, Benevento, Italy., ENEA, Portici Research Center, P.le E. Fermi 1, I-80055 Portici, Napoli, Italy., Institute of Biostructure and Bioimaging, National Research Council, I-80143, Napoli, Italy., Optoelectronics Group, Department of Engineering, University of Sannio, I-82100, Benevento, Italy. a.cusano@unisannio.it.,
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Microgel assisted Lab-on-Fiber Optrode (dominio pubblico) (98 visite)

Contiene: [X]      Estesa         Autori: [X]      Tipo di lavoro: [X]
Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
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Giaquinto M, Ricciardi A, Aliberti A, Micco A, Bobeico E, Ruvo M, Cusano A
* Light-microgel interaction in resonant nanostructures (42 visite)
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic), 2018 Jun 19; 8(1): 9331-9331.
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Giaquinto M, Micco A, Aliberti A, Bobeico E, La Ferrara V, Ruvo M, Ricciardi A, Cusano A
* Optimization Strategies for Responsivity Control of Microgel Assisted Lab-On-Fiber Optrodes (77 visite) (PDF 98 visite)
Sensors (ISSN: 1424-8220linking), 2018 Apr 6; 18(4): N/D-N/D.
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Magrì A, Di Natale G, Rizzarelli E
* Copper-assisted interaction between amyloid-beta and prion: Ternary metal complexes with A beta N-terminus and octarepeat (55 visite)
Inorg Chim Acta, 2017; N/D: N/D-N/D.
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Calce E, Petricci E, Saviano M, De Luca S
* Green microwave-assisted procedure to generate bio-based pectin materials (59 visite)
Sustainable Chemistry And Pharmacy, 2017; 5: 127-130.
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Calce E, Mercurio F, Leone M, Saviano M, De Luca S
* Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process (121 visite)
Carbohydr Polym (ISSN: 0144-8617, 1879-1344electronic, 0144-8617linking), 2016 Feb; 143: 84-89.
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Mollica A, Locatelli M, Macedonio G, Carradori S, Sobolev AP, De Salvador RF, Monti SM, Buonanno M, Zengin G, Angeli A, Supuran CT
* Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars (68 visite)
J Enzyme Inhib Med Chem, 2016; 31(sup4): N/D-N/D.
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Nande R, Greco A, Gossman MS, Lopez JP, Claudio L, Salvatore M, Brunetti A, Denvir J, Howard CM, Claudio PP
* Microbubble-assisted p53, RB, and p130 gene transfer in combination with radiation therapy in prostate cancer (141 visite)
Current Gene Therapy (ISSN: 1875-5631, 1566-5232), 2013 Jun 1; 13(3): 163-174.
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Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
* Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study (94 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jan; 69: 137-140.
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Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
* Selective X-Ray Induced No-Photodissociation In Hemoglobin Crystals: Evidence From A Raman Assisted-Crystallographic Study (85 visite)
Acta Cryst D 69, 2013; 1: 137-140.
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D'Addio G, Cesarelli M, Lullo F, Clemente F, De Nunzio M, Pappone N
* Reproducibility of kinematics indexes of upper arm reaching movement in robot assisted therapy (73 visite)
2013 Federated Conference On Computer Science And Information Systems Fedcsis 2013 (ISSN: 9781-4673), 2012; N/D: 184-187.
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Giurato P, Candura A, Grasso G, Spoto G
* In situ identification of organic components of ink used in books from the 1900s by atmospheric pressure matrix assisted laser desorption ionization mass spectrometry (139 visite)
Appl Phys A (ISSN: 0947-8396), 2009 Nov; 97(2): 263-269.
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Massari R, Trotta C, Trinci G, Sala R, Basso A, Zappa E, Scopinaro F, Soluri A
* Feasibility study of a computer-assisted radioguided surgery system (88 visite) (PDF 92 visite)
Nuclear Instruments And Methods In Physics Research Section A, 2007; 583(2-3): 360-365.
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Monti SM, Gallo M, Ferracane R, Borrelli RC, Ritieni A, Greco ML, Graniti A, Fogliano V
* Analysis of bacterial lipodepsipeptides by matrix-assisted laser desorption/ionisation time-of-flight and high-performance liquid chromatography with electrospray mass spectrometry (108 visite)
Rapid Commun Mass Spectrom (ISSN: 0951-4198, 1097-0231electronic), 2001; 15(8): 623-628.
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Bonomo RP, Di Blasio B, Maccarrone G, Pavone V, Pedone C, Rizzarelli E, Saviano M, Vecchio G
Crystal and Molecular Structure of the [6-Deoxy-6-[(2-(4-imidazolyl)ethyl)amino]cyclomaltoheptaose]copper(II) Ternary Complex with L-Tryptophanate. Role of Weak Forces in the Chiral Recognition Process Assisted by a Metallocyclodextrin (147 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996 Jul 17; 35(15): 4497-4504.
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14 Records (14 escludendo Abstract e Conferenze).
Impact factor totale: 36.153 (36.153 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 38.437 (38.437 escludendo Abstract e Conferenze).







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