Extra-osseous (99m)Tc methylene diphosphonate uptake detected enlargement of the knee joint in patient with polyarthritis(218 visite) Caprio MG, Manganelli M, Limone S, Sorbillo M, Quarantelli M, Cuocolo A, Mainolfi CG
Sage Open Med Case Rep (ISSN: 2050-313xprint, 2050-313xlinking), 2017 Nov 14; 5: 2050313X17741824-2050313X17741824.
Tipo di articolo: Journal Article,
Impact factor: 0, Impact factor a 5 anni: 0
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Parole chiave: 99mtc Methylene Diphosphonate Extra-Osseous Uptake, Bone Scintigraphy, Knee Joint, Polyarthritis,
*** IBB - CNR *** Institute of Biostructure and Bioimaging, National Research Council, Naples, Italy., Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.,
Bone scintigraphy is a nuclear scanning test used to find abnormalities in the skeleton. Certain abnormal processes involving soft tissues can also cause skeletal accumulation of radiotracer during bone scintigraphy. We present a case of periarticular knee soft tissue (99m)Tc methylene diphosphonate uptake in a patient with asymmetric polyarthritis. A 33-year-old patient with asymmetric polyarthritis, skin lesions and joint pain underwent bone scintigraphy. Total body examination showed an extra-osseous uptake in periarticular soft tissue of knees joints. A detailed history checkup, physical examination and laboratory tests were carried out to understand the link between the extra-osseous uptake and the phosphonate binding in periarticular soft tissue. To improve the anatomical description of the soft tissue of the knees and to clarify the nature of the extra-skeletal (99m)Tc methylene diphosphonate uptake, magnetic resonance imaging scan was performed. (99m)Tc-labeled phosphonate binding has been reported in a number of extra-osseous conditions, but to our knowledge, there are a few cases showing bone tracer uptake in polyarthritis. In polyarthritic patients, whole-body bone scintigraphy were useful in examining the whole joints and detecting possible dubious extra-osseous uptake; in fact, it is able to select subjects who require further in-depth analysis, for example, magnetic resonance imaging.