Binetruy-Tournaire, R., Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis (2000) EMBO J, 19, pp. 1525-1533. , COI: 1:CAS:528:DC%2BD3cXislymt74%3D, PID: 10747021

Byrne, A.M., Bouchier-Hayes, D.J., Harmey, J.H., Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF) (2005) J Cell Mol Med, 9, pp. 777-794. , COI: 1:CAS:528:DC%2BD2sXlvFKhtLg%3D, PID: 16364190

Calvanese, L., Conformational features and binding affinities to cripto, ALK7 and ALK4 of nodal synthetic fragments (2015) J Pept Sci, 21, pp. 283-293. , COI: 1:CAS:528:DC%2BC2MXnvVeguw%3D%3D, PID: 25588905

Caporale, A., Sturlese, M., Schievano, E., Mammi, S., Peggion, E., Synthesis and structural studies of new analogues of PTH(1–11) containing calpha-tetra-substituted amino acids in position 8 (2010) Amino Acids, 39, pp. 1369-1379. , COI: 1:CAS:528:DC%2BC3cXhtlaqtLfK, PID: 20431900

Caporale, A., Gesiot, L., Sturlese, M., Wittelsberger, A., Mammi, S., Peggion, E., Design, conformational studies and analysis of structure–function relationships of PTH (1–11) analogues: the essential role of val in position 2 (2012) Amino Acids, 43, pp. 207-218. , COI: 1:CAS:528:DC%2BC38XotlOhur0%3D, PID: 21918876

Carmeliet, P., Jain, R.K., Angiogenesis in cancer and other diseases (2000) Nature, 407, pp. 249-257. , COI: 1:CAS:528:DC%2BD3cXmvVSls74%3D, PID: 11001068

Chorev, M., The partial retro-inverso modification: a road traveled together (2005) Biopolymers, 80, pp. 67-84. , COI: 1:CAS:528:DC%2BD2MXktFersrg%3D, PID: 15729688

D’Andrea, L.D., Romanelli, A., Di Stasi, R., Pedone, C., Bioinorganic aspects of angiogenesis (2010) Dalton Trans, 39, pp. 7625-7636. , PID: 20535417

De Rosa, L., Miniaturizing VEGF: peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic response (2016) Sci Rep, 6, p. 31295. , PID: 27498819

Detmar, M., Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis (1994) J Exp Med, 180, pp. 1141-1146. , COI: 1:CAS:528:DyaK2cXlsFCksbw%3D, PID: 8064230

Etayash, H., Jiang, K., Azmi, S., Thundat, T., Kaur, K., Real-time detection of breast cancer cells using peptide-functionalized microcantilever arrays (2015) Sci Rep, 5, p. 13967. , COI: 1:CAS:528:DC%2BC2MXhs1Sksr%2FN, PID: 26434765

Ferrara, N., Adamis, A.P., Ten years of anti-vascular endothelial growth factor therapy (2016) Nat Rev Drug Discov, 15, pp. 385-403. , COI: 1:CAS:528:DC%2BC28XoslSrtA%3D%3D, PID: 26775688

Ferrara, N., Kerbel, R.S., Angiogenesis as a therapeutic target (2005) Nature, 438, pp. 967-974. , COI: 1:CAS:528:DC%2BD2MXhtlSksrnI, PID: 16355214

Ferrara, N., Gerber, H.P., LeCouter, J., The biology of VEGF and its receptors (2003) Nat Med, 9, pp. 669-676. , COI: 1:CAS:528:DC%2BD3sXktFOnur4%3D, PID: 12778165

Fiori, N., Structure-function relationship studies of PTH(1–11) analogues containing sterically hindered dipeptide mimetics (2007) J Pept Sci, 13, pp. 504-512. , COI: 1:CAS:528:DC%2BD2sXhtVGjtLjN, PID: 17617795

Giordano, R.J., Structural basis for the interaction of a vascular endothelial growth factor mimic peptide motif and its corresponding receptors (2005) Chem Biol, 12, pp. 1075-1083. , COI: 1:CAS:528:DC%2BD2MXhtFers7%2FF, PID: 16242650

Giordano, R.J., From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway (2010) Proc Natl Acad Sci USA, 107, pp. 5112-5117. , COI: 1:CAS:528:DC%2BC3cXjvFGntb4%3D, PID: 20190181

Gongora-Benitez, M., Tulla-Puche, J., Albericio, F., Multifaceted roles of disulfide bonds. Peptides as therapeutics (2014) Chem Rev, 114, pp. 901-926. , COI: 1:CAS:528:DC%2BC3sXhs1yls7nJ, PID: 24446748

Guntert, P., Automated NMR structure calculation with CYANA (2004) Methods Mol Biol, 278, pp. 353-378. , COI: 1:CAS:528:DC%2BD2cXosVWiu7g%3D, PID: 15318003

Kaminski, G.A., Friesner, R.A., Tirado-Rives, J., Jorgensen, W.L., Evaluation and reparametrization of the OPLS-AA force field for proteins via comparison with accurate quantum chemical calculations on peptides (2001) J Phys Chem B, 105, pp. 6474-6487. , COI: 1:CAS:528:DC%2BD3MXislKhsLk%3D

Kaumaya, P.T., Foy, K.C., Peptide vaccines and targeting HER and VEGF proteins may offer a potentially new paradigm in cancer immunotherapy (2012) Future Oncol, 8, pp. 961-987. , COI: 1:CAS:528:DC%2BC38Xht1WlsL%2FJ, PID: 22894670

Li, Y.L., Zhao, H., Ren, X.B., Relationship of VEGF/VEGFR with immune and cancer cells: staggering or forward? (2016) Cancer Biol Med, 13, pp. 206-214. , PID: 27458528

Olsson, A.K., Dimberg, A., Kreuger, J., Claesson-Welsh, L., VEGF receptor signalling—in control of vascular function (2006) Nat Rev Mol Cell Biol, 7, pp. 359-371. , COI: 1:CAS:528:DC%2BD28XjslSktrc%3D, PID: 16633338

Park, S., In vivo monitoring of angiogenesis in a mouse hindlimb ischemia model using fluorescent peptide-based probes (2016) Amino Acids, 48, pp. 1641-1654. , COI: 1:CAS:528:DC%2BC28XmsVeit78%3D, PID: 27098931

Pierce, E.A., Avery, R.L., Foley, E.D., Aiello, L.P., Smith, L.E., Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization (1995) Proc Natl Acad Sci USA, 92, pp. 905-909. , COI: 1:CAS:528:DyaK2MXjsVKhsr0%3D, PID: 7846076

Ponticelli, S., Modulation of angiogenesis by a tetrameric tripeptide that antagonizes vascular endothelial growth factor receptor 1 (2008) J Biol Chem, 283, pp. 34250-34259. , COI: 1:CAS:528:DC%2BD1cXhsVelu7rK, PID: 18922791

Porto, G., Identification of novel immunoregulatory molecules in human thymic regulatory CD4+ CD25+ T cells by phage display (2011) PLoS One, 6. , COI: 1:CAS:528:DC%2BC3MXhtV2ju7rL, PID: 21829599

Rink, R., To protect peptide pharmaceuticals against peptidases (2010) J Pharmacol Toxicol Methods, 61, pp. 210-218. , COI: 1:CAS:528:DC%2BC3cXksVeiur4%3D, PID: 20176117

Robinson, C.J., Stringer, S.E., The splice variants of vascular endothelial growth factor (VEGF) and their receptors (2001) J Cell Sci, 114, pp. 853-865. , COI: 1:CAS:528:DC%2BD3MXit1eit7c%3D, PID: 11181169

Rusnati, M., Presta, M., Angiogenic growth factors interactome and drug discovery: the contribution of surface plasmon resonance (2015) Cytokine Growth Factor Rev, 26, pp. 293-310. , COI: 1:CAS:528:DC%2BC2cXitVSnsr7N, PID: 25465594

Saito, H., Tsujitani, S., Ikeguchi, M., Maeta, M., Kaibara, N., Relationship between the expression of vascular endothelial growth factor and the density of dendritic cells in gastric adenocarcinoma tissue (1998) Br J Cancer, 78, pp. 1573-1577. , COI: 1:CAS:528:DyaK1MXhslKmug%3D%3D, PID: 9862566

Srabovic, N., Mujagic, Z., Mujanovic-Mustedanagic, J., Softic, A., Muminovic, Z., Rifatbegovic, A., Begic, L., Vascular endothelial growth factor receptor-1 expression in breast cancer and its correlation to vascular endothelial growth factor a (2013) Int J Breast Cancer, 2013, p. 746749. , PID: 24416596

Starzec, A., Vassy, R., Martin, A., Lecouvey, M., Di, B.M., Crepin, M., Perret, G.Y., Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1 (2006) Life Sci, 79, pp. 2370-2381. , COI: 1:CAS:528:DC%2BD28Xht1SgtrrF, PID: 16959272

Starzec, A., Structure-function analysis of the antiangiogenic ATWLPPR peptide inhibiting VEGF(165) binding to neuropilin-1 and molecular dynamics simulations of the ATWLPPR/neuropilin-1 complex (2007) Peptides, 28, pp. 2397-2402. , COI: 1:CAS:528:DC%2BD2sXhtlCqsrnN, PID: 17983687

Tarallo, V., De Falco, S., The vascular endothelial growth factors and receptors family: up to now the only target for anti-angiogenesis therapy (2015) Int J Biochem Cell Biol, 64, pp. 185-189. , COI: 1:CAS:528:DC%2BC2MXnvFSgsLY%3D, PID: 25936669

Tugyi, R., Uray, K., Ivan, D., Fellinger, E., Perkins, A., Hudecz, F., Partial d-amino acid substitution: improved enzymatic stability and preserved Ab recognition of a MUC2 epitope peptide (2005) Proc Natl Acad Sci USA, 102, pp. 413-418. , COI: 1:CAS:528:DC%2BD2MXptFSkuw%3D%3D, PID: 15630090

Van Der Spoel, D., Lindahl, E., Hess, B., Groenhof, G., Mark, A.E., Berendsen, H.J., GROMACS: fast, flexible, and free (2005) J Comput Chem, 26, pp. 1701-1718

von Wronski, M.A., Tuftsin binds neuropilin-1 through a sequence similar to that encoded by exon 8 of vascular endothelial growth factor (2006) J Biol Chem, 281, pp. 5702-5710

Wizigmann-Voos, S., Breier, G., Risau, W., Plate, K.H., Up-regulation of vascular endothelial growth factor and its receptors in von Hippel–Lindau disease-associated and sporadic hemangioblastomas (1995) Cancer Res, 55, pp. 1358-1364. , COI: 1:CAS:528:DyaK2MXktlKmtL4%3D, PID: 7533661

Wuthrich, K., (1986) NMR of proteins and nucleic acids, , Wiley, New York

}, document_type={Journal Article, }, affiliation={Istituto di Biostrutture e Bioimmagini del CNR, CIRPeB, University of Naples Federico II, via Mezzocannone, 16, 80134, Naples, Italy., CNR-IBB, via Mezzocannone, 16, 80134, Naples, Italy., DISTABiF, Universita degli Studi della Campania Luigi Vanvitelli, Via Vivaldi 43, 81100, Caserta, Italy., Angiogenesis Lab, Institute of Genetics and Biophysics-CNR, Via P. Castellino 111, 80131, Naples, Italy., Fresenius Kabi Anti Infectives srl, Via San Leonardo 23, 45010, Villadose, RO, Italy., Department of Pharmacy, University of Naples Federico II, Via D. Montesano 49, 80134, Naples, Italy., Istituto di Biostrutture e Bioimmagini del CNR, CIRPeB, University of Naples Federico II, via Mezzocannone, 16, 80134, Naples, Italy. menotti.ruvo@unina.it., CNR-IBB, via Mezzocannone, 16, 80134, Naples, Italy. menotti.ruvo@unina.it.,

DISTABiF, Università degli Studi della Campania Luigi Vanvitelli, Via Vivaldi 43, Caserta, 81100, Italy

}, ibbaffiliation={1}, }