Immunometabolic profiling of patients with multiple sclerosis identifies new biomarkers to predict disease activity during treatment with interferon beta-1a (107 visite)
Clin Immunol (ISSN: 1521-6616), 2017 Oct; 183: 249-253.
Tipo di articolo: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 3.557, Impact factor a 5 anni: 3.93
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030456724&doi=10.1016%2fj.clim.2017.08.011&partnerID=40&md5=2ebeca68413650b4f66ce4dacd051472
Parole chiave: Adjuvants, Immunologic Therapeutic Use , Biomarkers Blood , Humans , Interferon Beta-1a Therapeutic Use , Multiple Sclerosis, Relapsing-Remitting Blood Drug Therapy , Predictive Value Of Tests , Transcriptome Immunology , Autoimmunity , Ifn-Beta-1a , Il-6 , Leptin, Beta1a Interferon, Biological Marker, Cd40 Ligand, Interleukin 6, Monocyte Chemotactic Protein 1, Tumor Necrosis Factor Receptor, Immunological Adjuvant, Adult, Article, Body Mass, Clinical Article, Clinical Feature, Clinical Outcome, Clinical Practice, Corticosteroid Therapy, Disease Activity, Disease Association, Disease Course, Disease Duration, Disease Severity, Drug Formulation, Female, Follow Up, Immunoassay, Nuclear Magnetic Resonance Imaging, Priority Journal, Recurrence Risk, Risk Factor,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Neuroscienze, Scienze Riproduttive ed Odontostomatologiche, Universita degli Studi di Napoli "Federico II", Napoli, Italy.
Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Napoli, Italy.
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale delle Ricerche, Napoli, Italy.
Dipartimento di Sanita Pubblica, Universita degli Studi di Napoli "Federico II", Napoli, Italy.
Dipartimento di Biologia, Universita degli Studi di Napoli "Federico II", Napoli, Italy.
Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita degli Studi di Napoli "Federico II", Napoli, Italy. Electronic address: giuseppe.matarese@unina.it.
Riferimenti:
Lublin, F.D., Reingold, S.C., Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis (1996) Neurology, 46, pp. 907-91
Nylander, A., Hafler, D.A., Multiple sclerosis (2012) J. Clin. Invest., 122, pp. 1180-1188
Procaccini, C., Carbone, F., Di Silvestre, D., The proteomic landscape of human ex vivo regulatory and conventional T cells reveals specific metabolic requirements (2016) Immunity, 44, pp. 406-421
Zeng, H., Chi, H., Metabolic control of regulatory T cell development and function (2015) Trends Immunol., 36, pp. 3-12
Carbone, F., La Rocca, C., De Candia, P., Metabolic control of immune tolerance in health and autoimmunity (2016) Semin. Immunol., 28, pp. 491-504
Palavra, F., Almeida, L., Ambrósio, A.F., Reis, F., Obesity and brain inflammation: a focus on multiple sclerosis (2016) Obes. Rev., 17, pp. 211-224
Emamgholipour, S., Eshaghi, S.M., Hossein-nezhad, A., Mirzaei, K., Maghbooli, Z., Sahraian, M.A., Adipocytokine profile, cytokine levels and foxp3 expression in multiple sclerosis: a possible link to susceptibility and clinical course of disease (2013) PLoS One, 8
Matarese, G., Carrieri, P.B., La Cava, A., Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25 + regulatory T cells (2005) Proc. Natl. Acad. Sci. U. S. A., 102, pp. 5150-5155
Carbone, F., De Rosa, V., Carrieri, P.B., Regulatory T cell proliferative potential is impaired in human autoimmune disease (2014) Nat. Med., 20, pp. 69-74
Munger, K.L., Chitnis, T., Ascherio, A., Body size and risk of MS in two cohorts of US women (2009) Neurology, 73, pp. 1543-1550
Mokry, L.E., Ross, S., Timpson, N.J., Sawcer, S., Davey Smith, G., Richards, J.B., Obesity and Multiple Sclerosis: a Mendelian Randomization Study (2016) PLoS Med., 13
Hedström, A.K., Lima Bomfim, I., Barcellos, L., Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis (2014) Neurology, 82, pp. 865-872
Carrieri, P.B., Carbone, F., Perna, F., Longitudinal assessment of immuno-metabolic parameters in multiple sclerosis patients during treatment with glatiramer acetate (2015) Metabolism, 64, pp. 1112-1121
Poser, C.M., Brinar, V.V., Diagnostic criteria for multiple sclerosis (2001) Clin. Neurol. Neurosurg., 103, pp. 1-11
Polman, C.H., Reingold, S.C., Banwell, B., Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria (2011) Ann. Neurol., 69, pp. 292-302
Kurtzke, J.F., Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS) (1983) Neurology, 33, pp. 1444-1452
Scarpini, E., Galimberti, D., Baron, P., IP-10 and MCP-1 levels in CSF and serum from multiple sclerosis patients with different clinical subtypes of the disease (2002) J. Neurol. Sci., 195, pp. 41-46
Franciotta, D., Martino, G., Zardini, E., Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies (2001) J. Neuroimmunol., 115, pp. 192-198
Samoilova, E.B., Horton, J.L., Hilliard, B., Liu, T.S., Chen, Y., IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells (1998) J. Immunol., 161, pp. 6480-6486
Serada, S., Fujimoto, M., Mihara, M., IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis (2008) Proc. Natl. Acad. Sci. U. S. A., 105, pp. 9041-9046
Chen, Y.C., Yang, X., Miao, L., Serum level of interleukin-6 in Chinese patients with multiple sclerosis (2012) J. Neuroimmunol., 249, pp. 109-111
Matarese, G., Di Giacomo, A., Sanna, V., Requirement for leptin in the induction and progression of autoimmune encephalomyelitis (2001) J. Immunol., 166, pp. 5909-5916
Sanna, V., Di Giacomo, A., La Cava, A., Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses (2003) J. Clin. Invest., 111, pp. 241-250
De Rosa, V., Procaccini, C., La Cava, A., Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis (2006) J. Clin. Invest., 116, pp. 447-455
Batocchi, A.P., Rotondi, M., Caggiula, M., Leptin as a marker of multiple sclerosis activity in patients treated with interferon-beta (2003) J. Neuroimmunol., 139, pp. 150-154
Poggi, M., Jager, J., Paulmyer-Lacroix, O., The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes (2009) Diabetologia, 52, pp. 1152-1163
Chatzigeorgiou, A., Phieler, J., Gebler, J., Bornstein, S.R., Chavakis, T., CD40L stimulates the crosstalk between adipocytes and inflammatory cells (2013) Horm. Metab. Res., 45, pp. 741-747
Burman, J., Svensson, E., Fransson, M., The cerebrospinal fluid cytokine signature of multiple sclerosis: a homogenous response that does not conform to the Th1/Th2/Th17 convention (2014) J. Neuroimmunol., 277, pp. 153-159
Kato, K., Santana-Sahagún, E., Rassenti, L.Z., The soluble CD40 ligand sCD154 in systemic lupus erythematosus (1999) J. Clin. Invest., 104, pp. 947-955
Khoury, S.J., Orav, E.J., Guttmann, C.R., Kikinis, R., Jolesz, F.A., Weiner, H.L., Changes in serum levels of ICAM and TNF-R correlate with disease activity in multiple sclerosis (1999) Neurology, 53, pp. 758-764
Van Oosten, B.W., Barkhof, F., Truyen, L., Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2 (1996) Neurology, 47, pp. 1531-1534
Praksova, P., Stourac, P., Bednarik, J., Vlckova, E., Mikulkova, Z., Michalek, J., Immunoregulatory T cells in multiple sclerosis and the effect of interferon beta and glatiramer acetate treatment on T cell subpopulations (2012) J. Neurol. Sci., 319, pp. 18-23
Longhini, A.L., von Glehn, F., Brandão, C.O., Plasmacytoid dendritic cells are increased in cerebrospinal fluid of untreated patients during multiple sclerosis relapse (2011) J. Neuroinflammation, 8, p. 2
Durelli, L., Conti, L., Clerico, M., T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta (2009) Ann. Neurol., 65, pp. 499-509
Clin Immunol (ISSN: 1521-6616), 2017 Oct; 183: 249-253.
Tipo di articolo: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 3.557, Impact factor a 5 anni: 3.93
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030456724&doi=10.1016%2fj.clim.2017.08.011&partnerID=40&md5=2ebeca68413650b4f66ce4dacd051472
Parole chiave: Adjuvants, Immunologic Therapeutic Use , Biomarkers Blood , Humans , Interferon Beta-1a Therapeutic Use , Multiple Sclerosis, Relapsing-Remitting Blood Drug Therapy , Predictive Value Of Tests , Transcriptome Immunology , Autoimmunity , Ifn-Beta-1a , Il-6 , Leptin, Beta1a Interferon, Biological Marker, Cd40 Ligand, Interleukin 6, Monocyte Chemotactic Protein 1, Tumor Necrosis Factor Receptor, Immunological Adjuvant, Adult, Article, Body Mass, Clinical Article, Clinical Feature, Clinical Outcome, Clinical Practice, Corticosteroid Therapy, Disease Activity, Disease Association, Disease Course, Disease Duration, Disease Severity, Drug Formulation, Female, Follow Up, Immunoassay, Nuclear Magnetic Resonance Imaging, Priority Journal, Recurrence Risk, Risk Factor,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Neuroscienze, Scienze Riproduttive ed Odontostomatologiche, Universita degli Studi di Napoli "Federico II", Napoli, Italy.
Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Napoli, Italy.
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale delle Ricerche, Napoli, Italy.
Dipartimento di Sanita Pubblica, Universita degli Studi di Napoli "Federico II", Napoli, Italy.
Dipartimento di Biologia, Universita degli Studi di Napoli "Federico II", Napoli, Italy.
Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita degli Studi di Napoli "Federico II", Napoli, Italy. Electronic address: giuseppe.matarese@unina.it.
Riferimenti:
Lublin, F.D., Reingold, S.C., Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis (1996) Neurology, 46, pp. 907-91
Nylander, A., Hafler, D.A., Multiple sclerosis (2012) J. Clin. Invest., 122, pp. 1180-1188
Procaccini, C., Carbone, F., Di Silvestre, D., The proteomic landscape of human ex vivo regulatory and conventional T cells reveals specific metabolic requirements (2016) Immunity, 44, pp. 406-421
Zeng, H., Chi, H., Metabolic control of regulatory T cell development and function (2015) Trends Immunol., 36, pp. 3-12
Carbone, F., La Rocca, C., De Candia, P., Metabolic control of immune tolerance in health and autoimmunity (2016) Semin. Immunol., 28, pp. 491-504
Palavra, F., Almeida, L., Ambrósio, A.F., Reis, F., Obesity and brain inflammation: a focus on multiple sclerosis (2016) Obes. Rev., 17, pp. 211-224
Emamgholipour, S., Eshaghi, S.M., Hossein-nezhad, A., Mirzaei, K., Maghbooli, Z., Sahraian, M.A., Adipocytokine profile, cytokine levels and foxp3 expression in multiple sclerosis: a possible link to susceptibility and clinical course of disease (2013) PLoS One, 8
Matarese, G., Carrieri, P.B., La Cava, A., Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25 + regulatory T cells (2005) Proc. Natl. Acad. Sci. U. S. A., 102, pp. 5150-5155
Carbone, F., De Rosa, V., Carrieri, P.B., Regulatory T cell proliferative potential is impaired in human autoimmune disease (2014) Nat. Med., 20, pp. 69-74
Munger, K.L., Chitnis, T., Ascherio, A., Body size and risk of MS in two cohorts of US women (2009) Neurology, 73, pp. 1543-1550
Mokry, L.E., Ross, S., Timpson, N.J., Sawcer, S., Davey Smith, G., Richards, J.B., Obesity and Multiple Sclerosis: a Mendelian Randomization Study (2016) PLoS Med., 13
Hedström, A.K., Lima Bomfim, I., Barcellos, L., Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis (2014) Neurology, 82, pp. 865-872
Carrieri, P.B., Carbone, F., Perna, F., Longitudinal assessment of immuno-metabolic parameters in multiple sclerosis patients during treatment with glatiramer acetate (2015) Metabolism, 64, pp. 1112-1121
Poser, C.M., Brinar, V.V., Diagnostic criteria for multiple sclerosis (2001) Clin. Neurol. Neurosurg., 103, pp. 1-11
Polman, C.H., Reingold, S.C., Banwell, B., Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria (2011) Ann. Neurol., 69, pp. 292-302
Kurtzke, J.F., Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS) (1983) Neurology, 33, pp. 1444-1452
Scarpini, E., Galimberti, D., Baron, P., IP-10 and MCP-1 levels in CSF and serum from multiple sclerosis patients with different clinical subtypes of the disease (2002) J. Neurol. Sci., 195, pp. 41-46
Franciotta, D., Martino, G., Zardini, E., Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies (2001) J. Neuroimmunol., 115, pp. 192-198
Samoilova, E.B., Horton, J.L., Hilliard, B., Liu, T.S., Chen, Y., IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells (1998) J. Immunol., 161, pp. 6480-6486
Serada, S., Fujimoto, M., Mihara, M., IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis (2008) Proc. Natl. Acad. Sci. U. S. A., 105, pp. 9041-9046
Chen, Y.C., Yang, X., Miao, L., Serum level of interleukin-6 in Chinese patients with multiple sclerosis (2012) J. Neuroimmunol., 249, pp. 109-111
Matarese, G., Di Giacomo, A., Sanna, V., Requirement for leptin in the induction and progression of autoimmune encephalomyelitis (2001) J. Immunol., 166, pp. 5909-5916
Sanna, V., Di Giacomo, A., La Cava, A., Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses (2003) J. Clin. Invest., 111, pp. 241-250
De Rosa, V., Procaccini, C., La Cava, A., Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis (2006) J. Clin. Invest., 116, pp. 447-455
Batocchi, A.P., Rotondi, M., Caggiula, M., Leptin as a marker of multiple sclerosis activity in patients treated with interferon-beta (2003) J. Neuroimmunol., 139, pp. 150-154
Poggi, M., Jager, J., Paulmyer-Lacroix, O., The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes (2009) Diabetologia, 52, pp. 1152-1163
Chatzigeorgiou, A., Phieler, J., Gebler, J., Bornstein, S.R., Chavakis, T., CD40L stimulates the crosstalk between adipocytes and inflammatory cells (2013) Horm. Metab. Res., 45, pp. 741-747
Burman, J., Svensson, E., Fransson, M., The cerebrospinal fluid cytokine signature of multiple sclerosis: a homogenous response that does not conform to the Th1/Th2/Th17 convention (2014) J. Neuroimmunol., 277, pp. 153-159
Kato, K., Santana-Sahagún, E., Rassenti, L.Z., The soluble CD40 ligand sCD154 in systemic lupus erythematosus (1999) J. Clin. Invest., 104, pp. 947-955
Khoury, S.J., Orav, E.J., Guttmann, C.R., Kikinis, R., Jolesz, F.A., Weiner, H.L., Changes in serum levels of ICAM and TNF-R correlate with disease activity in multiple sclerosis (1999) Neurology, 53, pp. 758-764
Van Oosten, B.W., Barkhof, F., Truyen, L., Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2 (1996) Neurology, 47, pp. 1531-1534
Praksova, P., Stourac, P., Bednarik, J., Vlckova, E., Mikulkova, Z., Michalek, J., Immunoregulatory T cells in multiple sclerosis and the effect of interferon beta and glatiramer acetate treatment on T cell subpopulations (2012) J. Neurol. Sci., 319, pp. 18-23
Longhini, A.L., von Glehn, F., Brandão, C.O., Plasmacytoid dendritic cells are increased in cerebrospinal fluid of untreated patients during multiple sclerosis relapse (2011) J. Neuroinflammation, 8, p. 2
Durelli, L., Conti, L., Clerico, M., T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta (2009) Ann. Neurol., 65, pp. 499-509
Reliable immunologic biomarkers able to monitor disease course during <br>multiple sclerosis (MS) are still missing. We aimed at identifying <br>possible immunometabolic biomarkers able to predict the clinical outcome<br> in MS patients during treatment with interferon (IFN)-beta-1a. We <br>measured in 45 relapsing-remitting (RR) MS patients, blood circulating <br>levels of several immunometabolic markers, at enrolment, and correlated <br>their levels to disease activity and progression over time. Higher <br>levels of interleukin (IL)-6, soluble-CD40-ligand (sCD40L) and leptin at<br> baseline associated with a higher relapse rate and a greater risk of <br>experiencing at least one relapse in the following year. Higher values <br>of soluble tumor necrosis factor receptor (sTNF-R) and leptin at <br>baseline were predictive of a higher number of lesions in the following <br>one-year of follow up. In conclusion, our data suggest that an <br>immunometabolic profiling measuring IL-6, sCD40L, leptin and sTNF-R at <br>baseline, could represent a useful tool to predict disease course in <br>RRMS patients during treatment with IFN-beta-1a.
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Caprio MG, Russo C, Giugliano A, Ragucci M, Mancini M
* Vascular Disease in Patients with Multiple Sclerosis: A Review (159 visite) (PDF 117 visite)
J Vasc Med Surg, 2016; 4: 1-12.
Impact Factor: 0.163
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Palma G, Tedeschi E, Borrelli P, Cocozza S, Russo C, Liu S, Ye Y, Comerci M, Alfano B, Salvatore M, Haacke EM, Mancini M
* A Novel Multiparametric Approach to 3D Quantitative MRI of the Brain (356 visite) (PDF 194 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2015 Aug 18; 10(8): e0134963-e0134963.
Impact Factor: 3.057
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Miller DH, Fox RJ, Phillips JT, Hutchinson M, Havrdova E, Kita M, Wheeler-kingshott CA, Tozer DJ, Macmanus DG, Yousry TA, Goodsell M, Yang M, Zhang R, Viglietta V, Dawson KT
* Effects of delayed-release dimethyl fumarate on MRI measures in the phase 3 CONFIRM study (53 visite)
Neurology (ISSN: 0028-3878linking, 1526-632x), 2015 Mar 17; 84 (11 ): 1145-1152.
Impact Factor: 5.065
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Postiglione E, Criscuolo C, Cianflone A, Lanzillo R, Mancini M, Tedeschi E, Liuzzi R, Vacca G, Vastola M, Capasso M, Mancino T, Mormile R, Passannanti A, Palma G, Caprio M, Incoronato M, Salvatore M, Brescia-Morra V
* AN INTERIM ANALYSIS ON SUSCEPTIBILITY TO VASCULAR ALTERATIONS IN MS AND ALS (206 visite)
Veins And Lymphatics (ISSN: 2279-7483), 2015; 4(s1): 21-22.
Impact Factor: 0
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Canna A, Palma G, Tedeschi E, Cocozza S, Lanzillo R, Russo C, Borrelli P, Postiglione E, Liuzzi R, Criscuolo C, Brescia-Morra V, Mancini M, Salvatore M
* ASSESSING THE CORRELATION BETWEEN IRON DEPOSIT IN THE BASAL GANGLIA AND FLOW ABNORMALITIES IN THE NECK VEINS WITH MRI: PRELIMINARY EXPERIENCE (176 visite)
Veins And Lymphatics (ISSN: 2279-7483), 2015; 4(s1): 20-21.
Impact Factor: 0
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Cervo A, Caprio MG, Ragucci M, Mancini M
* CEREBRAL CIRCULATION IN PATIENTS WITH MULTIPLE SCLEROSIS. A COLOR-DOPPLER STUDY OF EXTRACRANIAL ARTERIAL AND VENOUS VESSELS (151 visite)
Veins And Lymphatics (ISSN: 2279-7483), 2015; 4(s1): 12-12.
Impact Factor: 0
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Cocozza S, Canna A, Lanzillo R, Palma G, Postiglione E, Russo C, Borrelli P, Brescia Morra V, Brunetti A, Salvatore M, Tedeschi E
* Correlation between Neck Venous Drainage and Multiple Sclerosis (141 visite)
Rsna 101st Scientific Assembly And Annual Meeting, 2015; N/D: N/D-N/D.
Impact Factor: 0
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Cianflone A, Criscuolo C, Lanzillo R, Liuzzi R, Mancini M, Tedeschi E, Postiglione E, Vacca G, Vacchiano V, Moccia M, VastoLa M, Puorro G, Marsili A, Incoronato M, Salvatore M, Brescia-Morra V
* INCREASED ENDOTHELIN-1 SERUM LEVELS IN PATIENTS WITH MULTIPLE SCLEROSIS (234 visite)
Veins And Lymphatics (ISSN: 2279-7483), 2015; 4(s1): 22-22.
Impact Factor: 0
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Patti F, De Stefano M, Lavorgna L, Messina S, Chisari CG, Ippolito D, Lanzillo R, Vacchiano V, Realmuto S, Valentino P, Coniglio G, Buccafusca M, Paolicelli D, D'Ambrosio A, Montella P, Morra VB, Savettieri G, Alfano B, Gallo A, Simone I, Viterbo R, Zappia M, Bonavita S, Tedeschi G
* Lesion load may predict long-term cognitive dysfunction in multiple sclerosis patients (215 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2015; 10(3): N/D-N/D.
Impact Factor: 3.057
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Criscuolo C, Carbone R, Lieto M, Peluso S, Guacci A, Filla A, Quarantelli M, Lanzillo R, Brescia Morra V, De Michele G
* SPG5 and multiple sclerosis: Clinical and genetic overlap? (142 visite)
Acta Neurol Scand (ISSN: 0001-6314, 1600-0404), 2015; 133(6): 410-414.
Impact Factor: 2.559
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Moccia M, Erro R, Montella S, Carotenuto A, Pappata S, Orefice G
* Diagnostic challenges of Parkinsonism occurring in multiple sclerosis (122 visite)
Acta Neurol Belg (ISSN: 0300-9009), 2014 Oct 12; 115(3): 513-515.
Impact Factor: 0.894
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Lanzillo R, Liuzzi R, Vallefuoco L, Moccia M, Amato L, Vacca G, Vacchiano V, Portella G, Brescia Morra V
* JC virus antibody index in natalizumab-treated patients: correlations with John Cunningham virus DNA and C-reactive protein level (134 visite)
Ther Clin Risk Manag (ISSN: 1178-203x), 2014 Oct 9; 10: 807-814.
Impact Factor: 1.469
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Lanzillo R, Quarantelli M, Veria V, Orefice G, Marrosu MG, Trojano M, Amato MP, Francia AM, Florio C, Tedeschi G, Bellantonio P, Annunziata P, Comerci M, Brunetti A, Bonavita V, Alfano B, Marini S, Pozzilli C, Morra VB
* Brain atrophy in relapsing-remitting multiple sclerosis patients treated with interferon-beta and atorvastatin (The ARIANNA study) (215 visite)
Eur J Neurol (ISSN: 1351-5101, 1468-1331electronic), 2014 May; 21(S.I.Suppl.1): 58-58.
Impact Factor: 4.055
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Tedeschi E, Lanzillo R, Mancini M, Russo C, Cianflone A, Liuzzi R, Cocozza S, Postiglione E, Palma G, Caprio MG, Incoronato MR, Criscuolo C, Brescia Morra V, Salvatore M
* Imaging Of Brain Perfusion In Multiple Sclerosis And Neurodegenerative Diseases: Association With Endothelial Factors. An Interim Analysis (185 visite) (PDF 144 visite)
2014 Joint Actrims-Ectrims Meeting, 2014 Apr 28; N/D: N/D-N/D.
Impact Factor: 0
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Mancini M, Lanzillo R, Liuzzi R, Di Donato O, Ragucci M, Monti S, Salvatore E, Morra VB, Salvatore M
* Internal jugular vein blood flow in multiple sclerosis patients and matched controls (181 visite) (PDF 147 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2014 Mar 27; 9(3): e92730-e92730.
Impact Factor: 3.234
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Lavorgna L, Bonavita S, Ippolito D, Lanzillo R, Salemi G, Patti F, Valentino P, Coniglio G, Buccafusca M, Paolicelli D, D'Ambrosio A, Bresciamorra V, Savettieri G, Zappia M, Alfano B, Gallo A, Simone I, Tedeschi G
* Clinical And Magnetic Resonance Imaging Predictors Of Disease Progression In Multiple Sclerosis: A Nine-Year Follow-Up Study (247 visite) (PDF 165 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970), 2014 Feb; 20(2): 220-226.
Impact Factor: 4.822
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Ristori G, Romano S, Cannoni S, Visconti A, Tinelli E, Mendozzi L, Cecconi P, Lanzillo R, Quarantelli M, Buttinelli C, Gasperini C, Frontoni M, Coarelli G, Caputo D, Bresciamorra V, Vanacore N, Pozzilli C, Salvetti M
* Effects of Bacille Calmette-Guerin after the first demyelinating event in the CNS (165 visite)
Neurology (ISSN: 0028-3878, 1526-632x, 0028-3878linking), 2014 Jan 7; 82(1): 41-48.
Impact Factor: 8.185
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Clerico M, De Mercanti S, Versino E, Piazza F, Gned D, Brescia Morra V, Lanzillo R, Amato L, Quarantelli M, Ghezzi A, Bianchi A, Baroncini D, Salemi G, Realmuto S, Ferro MT, Vitetta F, Donghia M, Paolicelli D, Trojano M, Durelli L
* Management of multiple sclerosis patients after the 24th Natalizumab course: the Ty-STOP study (153 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2013 Oct; 19(11): N/D-N/D.
Impact Factor: 4.863
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Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Zaratin P, Mancardi G, Mancini M
* Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study (127 visite)
Mult Scler (ISSN: 1477-0970, 1352-4585, 1352-4585linking), 2013 Oct; 19(11): 1508-1517.
Impact Factor: 4.863
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Lanzillo R, Bonavita S, Quarantelli M, Vacca G, Lus G, Amato L, Carotenuto A, Tedeschi G, Orefice G, Brescia Morra V
* Natalizumab is effective in multiple sclerosis patients switching from other disease modifying therapies in clinical practice (125 visite)
Neurol Sci (ISSN: 1590-1874, 1590-0187, 1590-3478), 2013 Apr; 34(4): 521-528.
Impact Factor: 0.38
Dettagli Esporta in BibTeX Esporta in EndNote
Lanzillo R, Mancini M, Liuzzi R, Di Donato O, Salvatore E, Maglio V, Vacca G, Amato L, D'Anna G, Brunetti A, Brescia Morra V
* Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon (194 visite)
Bmc Neurol (ISSN: 1471-2377), 2013 Feb 13; 13: 20-20.
Impact Factor: 2.486
Dettagli Esporta in BibTeX Esporta in EndNote
Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Mancardi G, Mancini M
* Italian Multicentre Observational Study Of The Prevalence Of Ccsvi In Multiple Sclerosis (cosmo Study): Rationale, Design, And Methodology (128 visite)
Neurol Sci, 2013 Jan; N/D: N/D-N/D.
Impact Factor: 1.362
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Lanzillo R, Quarantelli M, Bonavita S, Ventrella G, Lus G, Vacca G, Prinster A, Orefice G, Tedeschi G, Brescia Morra V
* Natalizumab vs interferon beta 1a in relapsing-remitting multiple sclerosis: A head-to-head retrospective study (162 visite)
Acta Neurol Scand (ISSN: 0001-6314, 1600-0404), 2012 Nov; 126(5): 306-314.
Impact Factor: 2.474
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Brescia Morra V, Alfano B, Lanzillo R, Quarantelli M, Comerci M, Marini S, Vacca G, Amato MP, Trojano M, Brunetti A, Pozzilli C
* Efficacy, Safety And Tolerability Of Atorvastatin In Patients With Relapsing-Remitting Multiple Sclerosis In Treatment With Interferon-Beta (arianna): A Multicentre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group-Study, Lyon. France (224 visite)
Proceedings Of The 23rd Ectrims Meeting Lyon France, 2012 Oct 10; AbstractBook: 477-477.
Impact Factor: 0
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Brescia Morra V, Alfano B, Lanzillo R, Quarantelli M, Comerci M, Marini S, Vacca G, Amato MP, Trojano M, Brunetti A, Pozzilli C
* Efficacy, safety and tolerability of Atorvastatin in patients with Relapsing-remitting multiple sclerosis in treAtment with INterferoN-beta (ARIANNA): a multicentre, randomised, double-blind, placebo-controlled, parallel-group-study (206 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2012 Oct; 18: 197-197.
Impact Factor: 4.472
Dettagli Esporta in BibTeX Esporta in EndNote
Mancini M, Morra VB, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Salvatore E, Brunetti A, Iaccarino V, Salvatore M
* Multiple sclerosis: cerebral circulation time (152 visite)
Radiology (ISSN: 1527-1315, 0033-8419, 1527-1315electronic), 2012 Mar; 262(3): 947-955.
Impact Factor: 6.339
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Caraci F, Spampinato S, Sortino MA, Bosco P, Battaglia G, Bruno V, Drago F, Nicoletti F, Copani A
* Dysfunction of TGF-β1 signaling in Alzheimer's disease: Perspectives for neuroprotection (306 visite)
Cell Tissue Res (ISSN: 0302-766x), 2012 Jan; 347(1): 291-301.
Impact Factor: 3.677
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Mancini M, Brescia Morra V, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Brunetti A, Salvatore M
* Contrast-Enhanced Ultrasound Evaluation Of The Cerebral Circulation Time In Patients With Multiple Sclerosis (129 visite)
J Ultrasound Med, 2012; N/D: 49-49.
Impact Factor: 1.532
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Malferrari G, Del Sette M, Zedde M, Sanguigni S, Carraro C, Baracchini C, Mancini M, Stolz E
* Italian multicenter study on venous hemodynamics in multiple sclerosis: Advanced Sonological Protocol (168 visite)
Perspect Med (ISSN: 2211-968x), 2012; 1-12: 399-403.
Impact Factor: 1.132
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Lanzillo R, Di Somma C, Quarantelli M, Ventrella G, Gasperi M, Prinster A, Vacca G, Pivonello C, Orefice G, Colao A, Morra VB
* Insulin-like growth factor (IGF)-I and IGF-binding protein-3 serum levels in relapsing-remitting and secondary progressive multiple sclerosis patients (169 visite)
Eur J Neurol (ISSN: 1351-5101, 1468-1331electronic), 2011 Dec; 18(12): 1402-1406.
Impact Factor: 3.692
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Bastianello S, Romani A, Viselner G, Tibaldi EC, Giugni E, Altieri M, Cecconi P, Mendozzi L, Farina M, Mariani D, Galassi A, Quattrini C, Mancini M, Brescia VM, Lagace A, Mcdonald S, Bono G, Bergamaschi R
* Chronic cerebrospinal venous insufficiency in multiple sclerosis: clinical correlates from a multicentre study (144 visite)
Bmc Neurol (ISSN: 1471-2377), 2011 Oct 26; 11: 132-132.
Impact Factor: 2.167
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Bastianello S, Giugni E, Amato MP, Tola MR, Trojano M, Galletti S, Luccichenti G, Quarantelli M, Picconi O, Patti F, COGIMUS
* Changes In Magnetic Resonance Imaging Disease Measures Over 3 Years In Mildly Disabled Patients With Relapsing-Remitting Multiple Sclerosis Receiving Interferon Beta-1a In The Cognitive Impairment In Multiple Sclerosis (cogimus) Study (153 visite) (PDF 144 visite)
Bmc Neurol (ISSN: 1471-2377), 2011 Oct 14; 11: 125-125.
Impact Factor: 2.167
Dettagli Esporta in BibTeX Esporta in EndNote
Calabrese V, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ
* Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity (261 visite)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 279-304.
Impact Factor: 9.97
Dettagli Esporta in BibTeX Esporta in EndNote
Alfano B, Comerci M, Larobina M, Prinster A, Hornak JP, Selvan SE, Amato U, Quarantelli M, Tedeschi G, Brunetti A, Salvatore M
* An MRI digital brain phantom for validation of segmentation methods (266 visite) (PDF 558 visite)
Med Image Anal (ISSN: 1361-8415, 1361-8423, 1361-8415linking), 2011 Jun; 15(3): 329-339.
Impact Factor: 4.424
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Lanzillo R, Orefice G, Prinster A, Ventrella G, Liuzzi R, Scarano V, Florio C, Vacca G, Brunetti A, Alfano B, Brescia Morra V, Bonavita V
* Predictive factors of neutralizing antibodies development in relapsing-remitting multiple sclerosis patients on interferon Beta-1b therapy (120 visite) (PDF 138 visite)
Neurol Sci (ISSN: 1590-1874, 1590-3478), 2011 Apr; 32(2): 287-292.
Impact Factor: 1.315
Dettagli Esporta in BibTeX Esporta in EndNote
Dinacci D, Tessitore A, Russo AA, De Bonis ML, Lavorgna L, Picconi O, Sacco R, Bonavita S, Gallo A, Servillo G, Marcuccio L, Comerci M, Galletti P, Alfano B, Tedeschi G
* BDNF Val66Met polymorphism and brain volumes in multiple sclerosis (220 visite) (PDF 163 visite)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Feb; 32(1): 117-123.
Impact Factor: 1.315
Dettagli Esporta in BibTeX Esporta in EndNote
Lanzillo R, Di Somma C, Quarantelli M, Ventrella G, Vacca G, Liuzzi R, Amato L, Orefice G, Colao A, Brescia Morra V
* Growth Hormone Axis In Early Multiple Sclerosis Patients Before And After 2 Years Treatment With Interferon Beta-1b - An Interim Analysis (144 visite)
Proceedings Of The Xlii Meeting Of The Italian Society Of Neurology, 2011; nd: 360-360.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Lanzillo R, Orefice G, Quarantelli M, Rinaldi C, Prinster A, Ventrella G, Spitaleri D, Lus G, Vacca G, Carotenuto B, Salvatore E, Brunetti A, Tedeschi G, Brescia Morra V
* Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: A longitudinal controlled trial of combination therapy (176 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2010 Apr; 16(4): 450-454.
Impact Factor: 4.23
Dettagli Esporta in BibTeX Esporta in EndNote
Prinster A, Quarantelli M, Lanzillo R, Orefice G, Vacca G, Carotenuto B, Alfano B, Brunetti A, Brescia Morra V, Salvatore M
* A voxel-based morphometry study of disease severity correlates in relapsing- remitting multiple sclerosis (193 visite) (PDF 141 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2010 Jan; 16(1): 45-54.
Impact Factor: 4.23
Dettagli Esporta in BibTeX Esporta in EndNote
Lanzillo R, Di Somma C, Quarantelli M, Gasperi M, Ventrella G, Prinster A, Vacca G, Orefice G, Colao A, Morra VB
* Serum levels of insulin like growth factor-1 and insulin like growth factor binding protein-3 in relapsing and secondary progressive multiple sclerosis (183 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2009 Sep; 15(9): 1402-1406.
Impact Factor: 3.279
Dettagli Esporta in BibTeX Esporta in EndNote
Dinacci D, Russo AA, Tessitore A, De Bonis ML, Lavorgna L, Picconi O, Sacco R, Bonavita S, Gallo A, Servillo G, Comerci M, Galletti P, Alfano B, Tedeschi G
* BDNF V4166Met Polymorphism and Brain Volumes in Multiple Sclerosis: A Relationship Still Debated (187 visite)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2009 Mar 17; 72(11): N/D-N/D.
Impact Factor: 8.172
Dettagli Esporta in BibTeX Esporta in EndNote
Quarantelli M, Lanzillo R, Prinster A, Mollica C, Orefice G, Brunetti A, Vacca G, Salvatore M, Morra VB
* Relationship between Clinical Aspects in Early Phases of Relapsing-Remitting Multiple Sclerosis and Subsequent Brain Volume Changes (159 visite)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2009 Mar 17; 72(11): N/D-N/D.
Impact Factor: 8.172
Dettagli Esporta in BibTeX Esporta in EndNote
Tedeschi G, Dinacci D, Comerci M, Lavorgna L, Savettieri G, Quattrone A, Livrea P, Patti F, Morra VB, Servillo G, Orefice G, Paciello M, Prinster A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Brunetti A, Salemi G, D'Amelio M, Simone I, Salvatore M, Bonavita V, Alfano B
* Brain atrophy evolution and lesion load accrual in multiple sclerosis: A 2-year follow-up study (252 visite) (PDF 181 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2009 Feb; 15(2): 204-211.
Impact Factor: 3.279
Dettagli Esporta in BibTeX Esporta in EndNote
Morra VB, Prinster A, Lanzillo R, Quarantelli M, Vacca G, Mollica C, Schiavone V, Brunetti A, Salvatore E, Alfano B, Orefice G
* Correlation of disease severity and regional brain tissue loss in relapsing-remitting multiple sclerosis: a voxel-based morphometry study in a large population (203 visite) (PDF 141 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2008 Sep; 14: 45-54.
Impact Factor: 3.312
Dettagli Esporta in BibTeX Esporta in EndNote
Vicidomini C, Comerci M, Salvatore E, Quarantelli M, Varrone A, Evangelista L, Prinster A, Morra VB, Brunetti A, Salvatore M, Alfano B, Pappata S
* Combined Mri And Pet-18fdg Study In Patients With Primary Progressive (pp) And Relapsing Remitting (rr) Multiple Sclerosis (ms) (234 visite)
Abstract Book Of Dimi/Emil Annual Meeting 2008, 2008 Jun 1; N/D: N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Orefice G, Quarantelli M, Lanzillo R, Brunetti A, Salvatore P, Prinster A, Vacca G, Mollica C, Bonavita V, Morra VB, Prinster A
* An open-label randomised clinical trial of atorvastatin in combination with IFN Beta 1a in active multiple sclerosis patients: preliminary results (147 visite)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2008 Jun; 255: N/D-N/D.
Impact Factor: 2.536
Dettagli Esporta in BibTeX Esporta in EndNote
Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (234 visite) (PDF 161 visite)
J Neurol Sci (ISSN: 0022-510x), 2007 Dec 15; 263(1-2): 15-19.
Impact Factor: 2.315
Dettagli Esporta in BibTeX Esporta in EndNote
Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (266 visite)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
Dettagli Esporta in BibTeX Esporta in EndNote
Alfano B, Brunetti A, De Pietro G, Esposito A
* An ontology approach for classification of abnormal white matter in patients with Multiple Sclerosis (211 visite) (PDF 177 visite)
Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2007; 4799LNCS: 389-402.
Impact Factor: 0.302
Dettagli Esporta in BibTeX Esporta in EndNote
Lanzillo R, Prinster A, Scarano V, Liuzzi R, Coppola G, Florio C, Salvatore E, Schiavone V, Brunetti A, Muto M, Orefice G, Alfano B, Bonavita V, Brescia Morra V
* Neuropsychological assessment, quantitative MRI and ApoE gene polymorphisms in a series of MS patients treated with IFN beta-1b (139 visite) (PDF 135 visite)
J Neurol Sci (ISSN: 0022-510x), 2006 Jun 15; 245(1-2): 141-145.
Impact Factor: 2.412
Dettagli Esporta in BibTeX Esporta in EndNote
Prinster A, Quarantelli M, Orefice G, Lanzillo R, Brunetti A, Mollica C, Salvatore E, Morra VB, Coppola G, Vacca G, Alfano B, Salvatore M
* Grey matter loss in relapsing-remitting multiple sclerosis: A voxel-based morphometry study (169 visite) (PDF 157 visite)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2006 Feb 1; 29(3): 859-867.
Impact Factor: 5.559
Dettagli Esporta in BibTeX Esporta in EndNote
Tedeschi G, Lavorgna L, Russo P, Prinster A, Dinacci D, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone IL, Salvatore M, Bonavita V, Alfano B
* Brain atrophy and lesion load in a large population of patients with multiple sclerosis (224 visite) (PDF 184 visite)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2005 Jul 26; 65(2): 280-285.
Impact Factor: 5.065
Dettagli Esporta in BibTeX Esporta in EndNote
Morra VB, Quarantelli M, Lanzillo R, Prinster A, Coppola G, Brunetti A, Salvatore E, Mollica C, Orefice R, Liuzzi R, Alfano B, Orefice G
* Normal and abnormal brain tissue volumes and neuropsychological status in relapsing-remitting multiple sclerosis (148 visite)
Eur J Neurol (ISSN: 1351-5101, 1468-1331electronic, 1351-5101linking), 2004 Sep; 11: N/D-N/D.
Impact Factor: 2.225
Dettagli Esporta in BibTeX Esporta in EndNote
Morra V, Quarantelli M, Lanzillo R, Prinster A, Coppola G, Brunetti A, Salvatore E, Mollica C, Orefice R, Liuzzi R, Alfano B, Orefice G
* Normal and abnormal brain tissue volumes and neuropsychological status in relapsing-remitting multiple sclerosis (144 visite)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2004 Jun; 251: N/D-N/D.
Impact Factor: 3.14
Dettagli Esporta in BibTeX Esporta in EndNote
Quarantelli M, Ciarmiello A, Morra VB, Orefice G, Larobina M, Lanzillo R, Schiavone V, Salvatore E, Alfano B, Brunetti A
* Brain tissue volume changes in relapsing-remitting multiple sclerosis: Correlation with lesion load (237 visite) (PDF 158 visite)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2003 Feb; 18(2): 360-366.
Impact Factor: 6.192
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Le Bihan D, Mangin JF, Poupon C, Clark CA, Pappata S, Molko N, Chabriat H
* Diffusion tensor imaging: Concepts and applications (207 visite)
J Magn Reson Imaging (ISSN: 1053-1807, 1522-2586electronic), 2001 Apr; 13(4): 534-546.
Impact Factor: 2.41
Dettagli Esporta in BibTeX Esporta in EndNote
Alfano B, Brunetti A, Larobina M, Quarantelli M, Tedeschi E, Ciarmiello A, Covelli EM, Salvatore M
Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis (268 visite) (PDF 527 visite)
J Magn Reson Imaging (ISSN: 1053-1807, 1522-2586electronic, 1053-1807linking), 2000 Dec; 12(6): 799-807.
Impact Factor: 1.302
Dettagli Esporta in BibTeX Esporta in EndNote
Alfano B, Quarantelli M, Brunetti A, Larobina M, Covelli EM, Tedeschi E, Salvatore M
Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation (270 visite) (PDF 503 visite)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic), 1998 Mar; 39(3): 497-499.
Impact Factor: 2.962
Dettagli Esporta in BibTeX Esporta in EndNote
Alfano B, Brunetti A, Ciarmiello A, Covelli E, Larobina M, Salvatore M
Automated lesion identification and volumetric measurement of lesion load in multiple sclerosis using a multispectral relaxometric MR approach (130 visite)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 1997 Nov; 205: N/D-N/D.
Impact Factor: 4.989
Dettagli Esporta in BibTeX Esporta in EndNote
Brunetti A, Tedeschi G, Di Costanzo A, Covelli EM, Aloj L, Bonavita S, Ciarmiello A, Alfano B, Salvatore M
White matter lesion detection in multiple sclerosis: Improved interobserver concordance with multispectral MRI display (190 visite) (PDF 154 visite)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1997 Sep; 244(9): 586-590.
Impact Factor: 1.976
Dettagli Esporta in BibTeX Esporta in EndNote
BRUNETTI A, TEDESCHI G, ALFANO B, DICOSTANZO A, ALOJ L, ARPAIA M, COVELLI E, BONAVITA S, SALVATORE M
Multiparametric characterization of lesions of the white matter in multiple sclerosis patients (134 visite)
Neuroradiology 1994, 1994; N/D: N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Pozzilli C, Bernardi S, Mansi L, Picozzi P, Iannotti F, Alfano B, Bozzao L, Lenzi GL, Salvatore M, Conforti P
Quantitative assessment of blood-brain barrier permeability in multiple sclerosis using 68-Ga-EDTA and positron emission tomography (143 visite) (PDF 156 visite)
J Neurol Neurosurg Psychiatry (ISSN: 0022-3050), 1988 Sep; 51(8): 1058-1062.
Impact Factor: 3.041
Dettagli Esporta in BibTeX Esporta in EndNote
Pota M, Esposito M, Megna R, De Pietro G, Quarantelli M, Brescia Morra V, Alfano B
Multivariate fuzzy analysis of brain tissue volumes and relaxation rates for supporting the diagnosis of relapsing-remitting multiple sclerosis (65 visite)
Biomedical Signal Processing And Control, N/D; 53: N/D-N/D.
Impact Factor: 2.943
Dettagli Esporta in BibTeX Esporta in EndNote
82 Records (58 escludendo Abstract e Conferenze).
Impact factor totale: 248.887 (199.035 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 265.442 (213.837 escludendo Abstract e Conferenze).
Impact factor totale: 248.887 (199.035 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 265.442 (213.837 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
Ultima modifica di Viviana De Rosa in data Friday 05 January 2018, 12:02:08
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