Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein(122 visite) Buonanno M, Coppola M, Di Lelio I, Molisso D, Leone M, Pennacchio F, Langella E, Rao R, Monti SM
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Mar; 27(3): 620-632.
Tipo di articolo: Journal Article,
Impact factor: 2.937, Impact factor a 5 anni: 3.256
Url: Non disponibile.
Parole chiave: Prosystemin, Spodoptera Littoralis, Natively Unfolded, Plant Defense, Solanaceae, Animals, Circular Dichroism, Gene Expression Regulation, Drug Effects, Intrinsically Disordered Proteins, Chemistry, Pharmacology, Growth, Development, Lycopersicon Esculentum, Genetics, Metabolism, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Plant Proteins, Protein Structure, Secondary,
*** IBB - CNR *** Institute of Biostructures and Bioimaging, CNR, Naples, Italy., Dipartimento di Agraria, Universita degli Studi di Napoli Federico II, Portici, NA, Italy.,
Prosystemin, originally isolated from Lycopersicon esculentum, is a tomato pro-hormone of 200 aminoacid residues which releases a bioactive peptide of 18 aminoacids called Systemin. This signaling peptide is involved in the activation of defense genes in solanaceous plants in response to herbivore feeding damage. Using biochemical, biophysical and bioinformatics approaches we characterized Prosystemin, showing that it is an intrinsically disordered protein possessing a few secondary structure elements within the sequence. Plant treatment with recombinant Prosystemin promotes early and late plant defense genes, which limit the development and survival of Spodoptera littoralis larvae fed with treated plants.
275 Records (264 escludendo Abstract e Conferenze). Impact factor totale: 1060.386 (1009.134 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 1093.541 (1040.738 escludendo Abstract e Conferenze).