Modulation of the Prototropic Exchange Rate in pH-Responsive Yb-HPDO3A Derivatives as ParaCEST Agents
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Modulation of the Prototropic Exchange Rate in pH-Responsive Yb-HPDO3A Derivatives as ParaCEST Agents (65 visite)

Dastru W, Menchise V, Ferrauto G, Fabretto S, Carrera C, Terreno E, Aime S, Delli Castelli D

Chemistryselect (ISSN: 2365-6549), 2018 Jun; 3(22): 6035-6041.



Tipo di articolo: Journal Article,

Impact factor: 1.505, Impact factor a 5 anni: 1.505

Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046678126&doi=10.1002%2fslct.201800283&partnerID=40&md5=387919f42ce20c2065a370958ed75251

Parole chiave: Contrast Agents, Lanthanide Complexes, Paracest, Ph Sensitive Agents,

Affiliazioni:

*** IBB - CNR ***
Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Center, University of Torino, Via Nizza 52, Torino, 10126, Italy
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale delle Ricerche, via Mezzocannone 16, Napoli, 80134, Italy


Riferimenti:

Zhang, S., Merritt, M., Woessner, D.E., Lenkinski, R.E., Sherry, A.D., (2003) Acc. Chem. Res., 36, pp. 783-79

Zhang, S., Malloy, C.R., Sherry, A.D., (2005) J. Am. Chem. Soc., 127, pp. 17572-17573

Woods, M., Woessner, D.E., Sherry, A.D., (2006) Chem Soc Rev, 35, pp. 500-511

Woods, M., Pasha, A., Zhao, P., Tircso, G., Chowdhury, S., Kiefer, G., Woessner, D.E., Sherry, A.D., (2011) Dalton Trans, 40, pp. 6759-6764

Viswanathan, S., Ratnakar, S.J., Green, K.N., Kovacs, Z., De León-Rodríguez, L.M., Sherry, A.D., (2009) Angew. Chem. Int. Ed., 48, pp. 9330-9333

Viswanathan, S., Kovacs, Z., Green, K.N., Ratnakar, S.J., Sherry, A.D., (2010) Chem. Rev., 110, pp. 2960-3018

van Zijl, P.C.M., Yadav, N.N., (2011) Magn. Reson. Med., 65, pp. 927-948

Terreno, E., Stancanello, J., Longo, D., Castelli, D.D., Milone, L., Sanders, H.M.H.F., Kok, M.B., Aime, S., (2009) Contrast Media Mol. Imaging, 4, pp. 237-247

Swietach, P., Vaughan-Jones, R.D., Harris, A.L., (2007) Cancer Metastasis Rev., 26, pp. 299-310

Sun, P.Z., Longo, D.L., Hu, W., Xiao, G., Wu, R., (2014) Phys. Med. Biol., 59, p. 4493

Sherry, A.D., Woods, M., (2008) Annu Rev Biomed Eng, 10, pp. 391-411

Rofstad, E.K., Mathiesen, B., Kindem, K., Galappathi, K., (2006) Cancer Res., 66, pp. 6699-6707

Ratnakar, S.J., Woods, M., Lubag, A.J.M., Kovács, Z., Sherry, A.D., (2008) J. Am. Chem. Soc., 130, pp. 6-7

Pumphrey, A., Yang, Z., Ye, S., Powell, D.K., Thalman, S., Watt, D.S., Abdel-Latif, A., Vandsburger, M., (2016) NMR Biomed., 29, pp. 74-83

Overly, C.C., Lee, K.D., Berthiaume, E., Hollenbeck, P.J., (1995) Proc. Natl. Acad. Sci., 92, pp. 3156-3160

Olatunde, A.O., Dorazio, S.J., Spernyak, J.A., Morrow, J.R., (2012) J. Am. Chem. Soc., 134, pp. 18503-18505

Gochberg, D.F., (2017) Magn. Reson. Imaging, 38, p. 233

Maxfield, F.R., (2014) Cold Spring Harb. Perspect. Biol., 6, p. 016931. , a, –a

Mani, T., Opina, A.C.L., Zhao, P., Evbuomwan, O.M., Milburn, N., Tircso, G., Kumas, C., Sherry, A.D., (2014) JBIC J. Biol. Inorg. Chem., 19, pp. 161-171

Mani, T., Tircsó, G., Togao, O., Zhao, P., Soesbe, T.C., Takahashi, M., Sherry, A.D., (2009) Contrast Media Mol. Imaging, 4, pp. 183-191

Li, A.X., Wojciechowski, F., Suchy, M., Jones, C.K., Hudson, R.H.E., Menon, R.S., Bartha, R., (2008) Magn. Reson. Med., 59, pp. 374-381

Lee, Y., Fukushima, S., Bae, Y., Hiki, S., Ishii, T., Kataoka, K., (2007) J. Am. Chem. Soc., 129, pp. 5362-5363

Langereis, S., Keupp, J., van Velthoven, J.L.J., de Roos, I.H.C., Burdinski, D., Pikkemaat, J.A., Grüll, H., (2009) J. Am. Chem. Soc., 131, pp. 1380-1381

Huang, Y., Coman, D., Ali, M.M., Hyder, F., (2015) Contrast Media Mol. Imaging, 10, pp. 51-58

Hingorani, D.V., Montano, L.A., Randtke, E.A., Lee, Y.S., Cárdenas-Rodríguez, J., Pagel, M.D., (2016) Contrast Media Mol. Imaging, 11, pp. 130-138

Du, K., Harris, T.D., (2016) J. Am. Chem. Soc., 138, pp. 7804-7807

Castelli, D.D., Ferrauto, G., Cutrin, J.C., Terreno, E., Aime, S., (2014) Magn. Reson. Med., 71, pp. 326-332

Dixon, W.T., Ren, J., Lubag, A.J.M., Ratnakar, J., Vinogradov, E., Hancu, I., Lenkinski, R.E., Sherry, A.D., (2010) Magn. Reson. Med., 63, pp. 625-632

Delli Castelli, D., Terreno, E., Aime, S., (2011) Angew. Chem. Int. Ed., 50, pp. 1798-1800

Castelli, D.D., Gianolio, E., Crich, S.G., Terreno, E., Aime, S., (2008) Coord. Chem. Rev., 252, pp. 2424-2443

Castelli, D.D., Caligara, M.C., Botta, M., Terreno, E., Aime, S., (2013) Inorg. Chem., 52, pp. 7130-7138

Christensen, K.A., Myers, J.T., Swanson, J.A., (2002) J. Cell Sci., 115, pp. 599-607

Caravan, P., Ellison, J.J., McMurry, T.J., Lauffer, R.B., (1999) Chem. Rev., 99, pp. 2293-2352

Cakić, N., Savić, T., Stricker-Shaver, J., Truffault, V., Platas-Iglesias, C., Mirkes, C., Pohmann, R., Angelovski, G., (2016) Chem Commun, 52, pp. 9224-9227

Aime, S., Botta, M., Fasano, M., Terreno, E., (1999) Acc. Chem. Res., 32, pp. 941-949

Aime, S., Barge, A., Bruce, J.I., Botta, M., Howard, J.A.K., Moloney, J.M., Parker, D., Woods, M., (1999) J. Am. Chem. Soc., 121, pp. 5762-5771

Muller, R.N., Vander Elst, L., Roch, A., Peters, J.A., Csajbok, E., Gillis, P., (2005) Relaxation by metal-containing nanosystems, 57, pp. 239-292. , Gossuin in Relaxation by metal-containing nanosystems

Ward, K.M., Balaban, R.S., (2000) Magn. Reson. Med., 44, pp. 799-802

Gregorio, E.D., Ferrauto, G., Gianolio, E., Aime, S., (2013) Contrast Media Mol. Imaging, 8, pp. 475-486

Zaiss, M., Angelovski, G., Demetriou, E., McMahon, M.T., Golay, X., Scheffler, K., (2018) Magn. Reson. Med., 79, pp. 1708-1721

Woessner, D.E., Zhang, S., Merritt, M.E., Sherry, A.D., (2005) Magn. Reson. Med., 53, pp. 790-799

Wang, M.-X., Cheng, X.-Y., Jin, M., Cao, Y.-L., Yang, Y.-P., Wang, J.-D., Li, Q., Liu, C.-F., (2015) Exp. Neurol., 271, pp. 112-121

Huotari, J., Helenius, A., (2011) EMBO J., 30, pp. 3481-3500



The aim of this work was to design new pH-sensitive paramagnetic chemical exchange saturation transfer (paraCEST) agents with a more acidic pH readout window with respect to the Yb complex of the 10-(2-hydroxypropyl)-1,4,7,10- tetraazacyclododecane-1,4,7-triacetic acid (HPDO3A). In particular, three HPDO3A derivatives have been synthesized by substituting the methyl group on the 2-hydroxypropyl arm with the electron withdrawing substituents –CF3, –CH2NH2 and –CH2OH. The Yb complexes have been characterized in terms of i) number and relative abundance of isomers present and, ii) pH sensitivity range in CEST applications. The influence of the introduced substituents on the –OH proton acidity and kex has been investigated and the new agents have been compared with the parent Yb-HPDO3A. All complexes showed an increased acidity and an enhanced exchange rate of the –OH proton. As a consequence, the pH-CEST sensitivity has been shifted to more acidic values. Eventually, the –CH2OH bearing derivative has been tested to assess the intra-endosomal pH which is too acidic to be determined with Yb-HPDO3A. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
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28 Records (25 escludendo Abstract e Conferenze).
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Impact factor a 5 anni totale: 119.289 (111.295 escludendo Abstract e Conferenze).







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