Genetics and management of locally advanced carcinomas of the head and neck: role of altered fractionation radiotherapy(169 views visite) Perri F, Ionna F, Muto P, Marzo MD, Caponigro F, Longo F, Vittoria Scarpati GD, Lorenzo GD, Giuliano M, Solla R
Future Sci Oa (ISSN: 2056-5623linking), 2018 Oct 26; 5(1): FSO347-FSO347.
Keywords Parole chiave: Egfr, Hpv, Accelerated, Cyclin D1, Genetics, Head And Neck, Hyperfractionated, Radiation Therapy, Radiotherapy, Translational Research,
Affiliations Affiliazioni: *** IBB - CNR ***
Head & Neck, Soft Tissue Sarcoma Medical Oncology Department, National Tumor Institute of Naples, IRCCS G Pascale, Napoli, Naples, Italy., Otolaryngology Unit, Department of Head & Neck, Soft Tissue Sarcoma & Thyroid Cancer, National Tumor Institute of Naples, IRCCS G Pascale, Napoli, Naples, Italy., Radiation Therapy Department, National Tumor Institute of Naples, IRCCS G Pascale, Napoli, Naples, Italy., Head & Neck - Soft Tissue Sarcoma Unit, IRCCS G Pascale, Naples, Italy., Medical Oncology Unit, POC SS Annunziata, Taranto, Italy., Department of Clinical Medicine & Surgery, University Federico II, Naples, Italy., Department of Medical Oncology, Lester & Sue Smith Breast Cancer Center, Baylor College of Medicine, Houston, TX, USA., Department of Radiation Oncology, Italian National Research Council, Institute of Biostructure & Bioimaging, Naples, Italy.,
References Riferimenti: Not available. Non disponibili.
Genetics and management of locally advanced carcinomas of the head and neck: role of altered fractionation radiotherapy
Squamous cell carcinoma of the head and neck (SCCHN) accounts for 5-7% of all malignancies. About 60% of newly diagnosed SCCHN are detected as locally advanced disease. Chemoradiation is a standard option and response rate to it is variable. Recently, a genetic classification of SCCHN has been proposed by Chung et al., who categorized all SCCHN into four subtypes. The basal-like variant is characterized by high expression of EGFR. Literature data suggest higher efficacy of accelerated and/or hyperfractionated radiotherapy, if compared with conventional radiotherapy in the subgroup of patients with high EGFR expression. In this review, we will describe the genetic factors able to guide treatment choice, with a focus on EGFR expression.
Genetics and management of locally advanced carcinomas of the head and neck: role of altered fractionation radiotherapy
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(227 visite) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 DettagliEsporta in BibTeXEsporta in EndNote
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(238 visite) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 DettagliEsporta in BibTeXEsporta in EndNote
356 Records (320 escludendo Abstract e Conferenze). Impact factor totale: 1531.688 (1421.094 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 1541.715 (1431.105 escludendo Abstract e Conferenze).
Last modified by Ultima modifica di Marco Comerci on in data Sunday 12 July 2020, 13:14:41 169 views visite. Last view on Ultima visita in data Monday 29 March 2021, 2:14:59