Lanthionine Peptides by S-Alkylation with Substituted Cyclic Sulfamidates promoted by Activated Molecular Sieves: Effects of the Sulfamidate Structure on the Yield
Lanthionine Peptides by S-Alkylation with Substituted Cyclic Sulfamidates promoted by Activated Molecular Sieves: Effects of the Sulfamidate Structure on the Yield(166 views visite) De Luca S, Digilio G, Verdoliva V, Tovillas P, Jimenez-oses G, Peregrina JM
J Org Chem (ISSN: 0022-3263linking), 2019 Nov 15; 84(22): 14957-14964.
Keywords Parole chiave: Not available. Non disponibili.
Affiliations Affiliazioni: *** IBB - CNR ***
Institute of Biostructures and Bioimaging , National Research Council , 80134 Naples , Italy. Department of Science and Technologic Innovation Universita del Piemonte Orientale "A. Avogadro" , 15121 Alessandria , Italy. Departamento de Quimica, Centro de Investigacion en Sintesis Quimica , Universidad de La Rioja , 26006 Logrono , Spain. CIC bioGUNE , Bizkaia Technology Park, Building 800 , 48170 Derio , Spain.
References Riferimenti: Not available. Non disponibili.
Lanthionine Peptides by S-Alkylation with Substituted Cyclic Sulfamidates promoted by Activated Molecular Sieves: Effects of the Sulfamidate Structure on the Yield
A green and efficient method for preparing lanthionine peptides by a highly chemoselective and stereochemically controlled procedure is presented. It involves an S-alkylation reaction, promoted by activated molecular sieves, on chiral cyclic sulfamidates, both N-protected and unprotected. Of note, the reaction yield was high also for cyclic sulfamidates bearing a free amine group, while other strategies failed to achieve a ring-opening nucleophilic reaction with N-unprotected substrates. To prove the feasibility of the procedure, the synthesis of a thioether ring B mimetic of the natural lantibiotic haloduracin beta was performed.
Lanthionine Peptides by S-Alkylation with Substituted Cyclic Sulfamidates promoted by Activated Molecular Sieves: Effects of the Sulfamidate Structure on the Yield
Lanthionine Peptides by S-Alkylation with Substituted Cyclic Sulfamidates promoted by Activated Molecular Sieves: Effects of the Sulfamidate Structure on the Yield
Aloj L, Aurilio M, Rinaldi V, D'Ambrosio L, Tesauro D, Peitl PK, Maina T, Mansi R, Von Guggenberg E, Joosten L, Sosabowski JK, Breeman WA, De Blois E, Koelewijn S, Melis M, Waser B, Beetschen K, Reubi JC, De Jong M * The EEE project(371 visite) Proc Int Cosm Ray Conf Icrc Universidad Nacional Autonoma De Mexico, 2007; 5(HEPART2): 977-980. Impact Factor:0 DettagliEsporta in BibTeXEsporta in EndNote
Vitiello M, Finamore E, Falanga A, Raieta K, Cantisani M, Galdiero F, Pedone C, Galdiero M, Galdiero S * Fusion in Coq(392 visite) Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2001; 2178LNCS: 583-596. Impact Factor:0.415 DettagliEsporta in BibTeXEsporta in EndNote
560 Records (528 escludendo Abstract e Conferenze). Impact factor totale: 2132.115 (2035.609 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 2189.346 (2083.925 escludendo Abstract e Conferenze).
Last modified by Ultima modifica di Stefania De Luca on in data Sunday 12 July 2020, 13:14:39 166 views visite. Last view on Ultima visita in data Saturday 23 January 2021, 1:43:38