Intestinimonas-like bacteria are important butyrate producers that 1 utilize Nε-fructosyllysine and lysine in formula-fed infants and adults(48 visite) Bui N, Troise AD, Nijsse B, Roviello GN, Fogliano V, Devos W
Journal Of Functional Foods, 2020 Apr; 70: 103974-103980.
Parole chiave: Maillard Reaction, Amadori Products, Dietary Advanced Glycation End-Products, 11 Protein Glycation, Butyrate Production
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Our study aims to investigate the role of Intestinimonas, Nεfructosyllysine (FL)-degrading bacterium, in infants and adults. We used lysine and subsequently FL in anaerobic serial dilutions of stools of infants and adults to enrich lysine and FL-degrading species. The fecal microbiota of adults are able to ferment lysine and FL to butyrate. Different groups of Intestinimonas spp. were detected from all lysine enrichments whereas the FL enrichments consisted of broader taxonomic groups with a reduced abundance of Intestinimonas-related species. Remarkably, the capability to degrade FL was only observed in formula-fed but not in breast-fed infants, which may relate to high contents of FL in formulas after thermal treatment. This possibility was supported by analyzing metagenomic datasets of 3-month and 4-month infants. Our data indicate the key role of Intestinimonas-like bacteria in FL degradation in formula-fed infants and adults as a profound example of adaptation of intestinal bacteria to dietary components.
10 Records (10 escludendo Abstract e Conferenze). Impact factor totale: 19.768 (19.768 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 25.767 (25.767 escludendo Abstract e Conferenze).