Department of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Laboratory of Developmental Neuropsychology, Department of Psychology, University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.
Institute of Biostructure and Bioimaging, National Research Council, 80100 Naples, Italy.
References Riferimenti: Not available. Non disponibili.
Multimodal MRI Assessment of Thalamic Structural Changes in Earthquake Survivors
Moving from the central role of the thalamus in the integration of inner and external stimuli and in the implementation of a stress-related response, the objective of the present study was to investigate the presence of any MRI structural and volumetric changes of the thalamic structures in earthquake witnesses. Forty-one subjects were included, namely 18 university students belonging to the experimental earthquake-exposed group (8 males and 10 females, mean age 24.5 ± 1.8 years) and a control group of 23 students not living in any earthquake-affected areas at the time of the earthquake (14 males and 9 females, mean age 23.7 ± 2.0 years). Instrumental MRI evaluation was performed using a 3-Tesla scanner, by acquiring a three-dimensional fast spoiled gradient-echo (FSPGR) sequence for volumetric analysis and an EPI (echoplanar imaging) sequence to extract fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values. As compared to the control one, the experimental group showed significantly lower gray matter volume in the mediodorsal nucleus of the left thalamus (p < 0.001). The dominant hemisphere thalamus in the experimental group showed higher mean ADC values and lower mean FA values as compared to the control group.
Multimodal MRI Assessment of Thalamic Structural Changes in Earthquake Survivors
Ciccarelli M, Sorriento D, Coscioni E, Iaccarino G, Santulli G * Adrenergic Receptors(215 visite) Endocrinol Of The Heart In Health And Dis (ISSN: 9780-1280311249780128031117), 2016; N/D: 285-315. Impact Factor:0 DettagliEsporta in BibTeXEsporta in EndNote
172 Records (152 escludendo Abstract e Conferenze). Impact factor totale: 652.384 (566.23 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 673.503 (586.067 escludendo Abstract e Conferenze).
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