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DNA/RNA: Building blocks of life under UV irradiation (60 visite)

Gustavsson T, Improta R, Markovitsi D

J Phys Chem Lett (ISSN: 1948-7185, 1948-7185electronic, 1948-7185linking), 2010 Jul 1; 1(13): 2025-2030.

Tipo di articolo: Journal Article,

Impact factor: 6.687

Impact factor a 5 anni: 6.91


Parole chiave: Building Blockes, Conical Intersection, Environmental Factors, Nonradiative Decays, Nucleic Acid Basis, Photo-Stability, Substituent And Solvent Effects, Ultra-Fast, Uv Irradiation, Quantum Chemistry, Excited States,

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77954307656&partnerID=40&md5=8e830a124ce8911ce7a9b9b5fe497180

During the last 10 years, intense experimental and theoretical work has proven the existence of ultrafast nonradiative decay routes for UV-excited monomeric nucleic acid bases, accounting for their high photostability. This mechanism has been explained by the occurrence of easily accessible conical intersections connecting the first excited ππ* state with the ground state. However, recent studies of substituent and solvent effects indicate that the situation is more complicated than what was initially thought, notably by the presence of dark excited states. Moreover, the actual shape of the excited-state potential energy surface may induce nonexponential dynamics. Further efforts are needed in order to clarify how various environmental factors affect the structural and dynamical aspects of the nucleic acid base excited states. © 2010 American Chemical Society.
Laboratoire Francis Perrin, CEA/DSM/IRAMIS/SPAM, CEA/Saclay, 91191 Gif-sur-Yvette, France
Crespo-Hernández, C.E., Cohen, B., Hare, P.M., Kohler, B., Ultrafast Excited-State Dynamics in Nucleic Acids (2004) Chem. Rev., 104, pp. 1977-202

Canuel, C., Mons, M., Piuzzi, F., Tardivel, B., Dimicoli, I., Elhanine, M., Excited States Dynamics of DNA and RNA Bases: Characterization of a Stepwise Deactivation Pathway in the Gas Phase (2005) J. Chem. Phys., 122, pp. 074316/1-074316/6

Pecourt, J.-M.L., Peon, J., Kohler, B., Ultrafast Internal Conversion of Electronically Excited RNA and DNA Nucleosides in Water (2000) J. Am. Chem. Soc., 122, pp. 9348-9349

Peon, J., Zewail, A.H., DNA/RNA Nucleotides and Nucleosides: Direct Measurement of Excited-State Lifetimes by Femtosecond Fluorescence Up-Conversion (2001) Chem. Phys. Lett., 348, pp. 255-262

Gustavsson, T., Sharonov, A., Markovitsi, D., Thymine, Thymidine and Thymidine 5′-Monophosphate Studied by Femtosecond Fluorescence Upconversion Spectroscopy (2002) Chem. Phys. Lett., 351, pp. 195-200

Pancur, T., Schwalb, N.K., Renth, F., Temps, F., Femtosecond fluorescence up-conversion spectroscopy of adenine and adenosine: Experimental evidence for the πσ*state? (2005) Chemical Physics, 313 (1-3), pp. 199-212. , DOI 10.1016/j.chemphys.2004.12.019

Karunakaran, V., Kleinermanns, K., Improta, R., Kovalenko, S.A., Photoinduced Dynamics of Guanosine Monophosphate in Water from Broad-Band Transient Absorption Spectroscopy and Quantum-Chemical Calculations (2009) J. Am. Chem. Soc., 131, pp. 5839-5850

Sharonov, A., Gustavsson, T., Carré, V., Renault, E., Markovitsi, D., Cytosine Excited State Dynamics Studied by Femtosecond Spectroscopy (2003) Chem. Phys. Lett., 380, pp. 173-180

Blancafort, L., Cohen, B., Hare, P.M., Kohler, B., Robb, M.A., Singlet Excited-State Dynamics of 5-Fluorocytosine and Cytosine: An Experimental and Computational Study (2005) J. Phys. Chem. A, 109, pp. 4431-4436

Gustavsson, T., Banyasz, A., Lazzarotto, E., Markovitsi, D., Scalmani, G., Frisch, M.J., Barone, V., Improta, R., Singlet Excited-State Behavior of Uracil and Thymine in Aqueous Solution: A Combined Experimental and Computational Study of 11 Uracil Derivatives (2006) J. Am. Chem. Soc., 128, pp. 607-619

Kwok, W.-M., Ma, C., Phillips, D.L., A Doorway State Leads to Photostability or Triplet Photodamage in Thymine DNA (2008) J. Am. Chem. Soc., 130, pp. 5131-5139

Towrie, M., Doorley, G.W., George, M.W., Parker, A.W., Quinn, S.J., Kelly, J.M., Ps-TRIR Covers All the Bases - Recent Advances in the Use of Transient IR for the Detection of Short-Lived Species in Nucleic Acids (2009) Analyst, 134, pp. 1265-1273

Billinghurst, B.E., Yeung, R., Loppnow, G.R., Excited-State Structural Dynamics of 5-Fluorouracil (2006) J. Phys. Chem. A, 110, pp. 6185-6191

Matsika, S., Radiationless Decay of Excited States of Uracil through Conical Intersections (2004) J. Phys. Chem. A, 108, pp. 7584-7590

Gustavsson, T., Sarkar, N., Lazzarotto, E., Markovitsi, D., Improta, R., Singlet Excited State Dynamics of Uracil and Thymine Derivatives. A Femtosecond Fluorescence Upconversion Study in Acetonitrile (2006) Chem. Phys. Lett., 429, pp. 551-557

Merchán, M., Gonzalez-Luque, R., Climent, T., Serrano-Andres, L., Rodriguez, E., Reguero, M., Pelaez, D., Unified Model for the Ultrafast Decay of Pyrimidine Nucleobases (2006) J. Phys. Chem. B, 110, pp. 26471-26476

Mercier, Y., Santoro, F., Reguero, M., Improta, R., The Decay from the Dark nπ* Excited State in Uracil: An Integrated CASPT2/CASSCF and PCM/TD-DFT Study in the Gas Phase and in Water (2008) J. Phys. Chem. B, 112, pp. 10769-10772

Santoro, F., Improta, R., Barone, V., Three-Dimensional Diabatic Models for the ππ* → nπ* Excited-State Decay of Uracil Derivatives in Solution (2009) Theor. Chem. Acc., 123, pp. 273-286

Blancafort, L., Energetics of Cytosine Singlet Excited-State Decay Paths

A Difficult Case for CASSCF and CASPT2 (2007) Photochem. Photobiol., 83, pp. 603-610

Hudock, H.R., Martinez, T.J., Excited-State Dynamics of Cytosine Reveal Multiple Intrinsic Subpicosecond Pathways (2008) ChemPhysChem, 9, pp. 2486-2490

Conti, I., Garavelli, M., Orlandi, G., Deciphering Low Energy Deactivation Channels in Adenine (2009) J. Am. Chem. Soc., 131, pp. 16108-16118

Serrano-Andrés, L., Merchán, M., Are the Five Natural DNA/RNA Base Monomers a Good Choice from Natural Selection? A Photochemical Perspective (2009) J. Photochem. Photobiol., C, 10, pp. 21-32

Hare, P.M., Crespo-Hernández, C.E., Kohler, B., Solvent-Dependent Photophysics of 1-Cyclohexyluracil: Ultrafast Branching in the Initial Bright State Leads Nonradiatively to the Electronic Ground State and a Long-Lived 1nπ* State (2006) J. Phys. Chem. B, 110, pp. 18641-18650

Santoro, F., Barone, V., Gustavsson, T., Improta, R., Solvent Effect on the Singlet Excited State Lifetimes of Nucleic Acid Bases: A Computational Study of 5-Fluorouracil and Uracil in Acetonitrile and Water (2006) J. Am. Chem. Soc., 128, pp. 16312-16322

Miannay, F.-A., Gustavsson, T., Banyasz, A., Markovitsi, D., Excited State Dynamics of dGMP Measured by Steady-state and Femtosecond Fluorescence Spectroscopy (2010) J. Phys. Chem. A, 114, pp. 3256-3263

Onidas, D., Markovitsi, D., Marguet, S., Sharonov, A., Gustavsson, T., Fluorescence Properties of DNA Nucleosides and Nucleotides: A Refined Steady-State and Femtosecond Investigation (2002) J. Phys. Chem. B, 106, pp. 11367-11374

Markovitsi, D., Sharonov, A., Onidas, D., Gustavsson, T., The Effect of Molecular Organisation in DNA Oligomers Studied by Femtosecond Fluorescence Spectroscopy (2003) ChemPhysChem, 3, pp. 303-305

Markovitsi, D., Gustavsson, T., Banyasz, A., Absorption of UV Radiation by DNA: Spatial and Temporal Features (2010) Mutat. Res. Rev., 704, pp. 21-28

Middleton, C.T., De La Harpe, K., Su, C., Law, Y.K., Crespo-Hernandez, C.E., Kohler, B., DNA Excited-State Dynamics: From Single Bases to the Double Helix (2009) Annu. Rev. Phys. Chem., 60, pp. 217-239

Doorley, G.W., McGovern, D.A., George, M.W., Towrie, M., Parker, A.W., Kelly, J.M., Quinn, S.J., Picosecond Transient Infrared Study of the Ultrafast Deactivation Processes of Electronically Excited B-DNA and Z-DNA Forms of [poly(dG-dC)]2 (2009) Angew. Chem., Int. Ed., 48, pp. 123-127

Vayá, I., Miannay, F.-A., Gustavsson, T., Markovitsi, D., High-Energy Long-Lived Excited States in DNA Double Strands (2010) ChemPhysChem, 11, pp. 987-989

Sobolewski, A.L., Domcke, W., On the Mechanism of Nonradiative Decay of DNA Bases: Ab initio and TDDFT Results for the Excited States of 9H-Adenine (2002) Eur. Phys. J. D, 20, pp. 369-374

Bensasson, R.V., Land, E.J., Truscott, T.G., (1993) Excited States and Free Radicals in Biology and Medicine, , Oxford University Press: Oxford, U.K

Salet, C., Bensasson, R., Studies on Thymine and Uracil Triplet Excited State in Acetonitrile and Water (1975) Photochem. Photobiol., 22, pp. 231-235

Hare, P.M., Middleton, C.T., Mertel, K.I., Herbert, J.M., Kohler, B., Time-Resolved Infrared Spectroscopy of the Lowest Triplet State of Thymine and Thymidine (2008) Chem. Phys., 347, pp. 383-392

Crespo-Hern ndez, C. E., Cohen, B., Hare, P. M., Kohler, B., Ultrafast Excited-State Dynamics in Nucleic Acids (2004) Chem. Rev., 104, pp. 1977-202

Pecourt, J. -M. L., Peon, J., Kohler, B., Ultrafast Internal Conversion of Electronically Excited RNA and DNA Nucleosides in Water (2000) J. Am. Chem. Soc., 122, pp. 9348-9349

Kwok, W. -M., Ma, C., Phillips, D. L., A Doorway State Leads to Photostability or Triplet Photodamage in Thymine DNA (2008) J. Am. Chem. Soc., 130, pp. 5131-5139

Billinghurst, B. E., Yeung, R., Loppnow, G. R., Excited-State Structural Dynamics of 5-Fluorouracil (2006) J. Phys. Chem. A, 110, pp. 6185-6191

Merch n, M., Gonzalez-Luque, R., Climent, T., Serrano-Andres, L., Rodriguez, E., Reguero, M., Pelaez, D., Unified Model for the Ultrafast Decay of Pyrimidine Nucleobases (2006) J. Phys. Chem. B, 110, pp. 26471-26476

Hudock, H. R., Martinez, T. J., Excited-State Dynamics of Cytosine Reveal Multiple Intrinsic Subpicosecond Pathways (2008) ChemPhysChem, 9, pp. 2486-2490

Serrano-Andr s, L., Merch n, M., Are the Five Natural DNA/RNA Base Monomers a Good Choice from Natural Selection? A Photochemical Perspective (2009) J. Photochem. Photobiol., C, 10, pp. 21-32

Hare, P. M., Crespo-Hern ndez, C. E., Kohler, B., Solvent-Dependent Photophysics of 1-Cyclohexyluracil: Ultrafast Branching in the Initial Bright State Leads Nonradiatively to the Electronic Ground State and a Long-Lived 1n * State (2006) J. Phys. Chem. B, 110, pp. 18641-18650

Miannay, F. -A., Gustavsson, T., Banyasz, A., Markovitsi, D., Excited State Dynamics of dGMP Measured by Steady-state and Femtosecond Fluorescence Spectroscopy (2010) J. Phys. Chem. A, 114, pp. 3256-3263

Middleton, C. T., De La Harpe, K., Su, C., Law, Y. K., Crespo-Hernandez, C. E., Kohler, B., DNA Excited-State Dynamics: From Single Bases to the Double Helix (2009) Annu. Rev. Phys. Chem., 60, pp. 217-239

Doorley, G. W., McGovern, D. A., George, M. W., Towrie, M., Parker, A. W., Kelly, J. M., Quinn, S. J., Picosecond Transient Infrared Study of the Ultrafast Deactivation Processes of Electronically Excited B-DNA and Z-DNA Forms of [poly (dG-dC)] 2 (2009) Angew. Chem., Int. Ed., 48, pp. 123-127

Vay, I., Miannay, F. -A., Gustavsson, T., Markovitsi, D., High-Energy Long-Lived Excited States in DNA Double Strands (2010) ChemPhysChem, 11, pp. 987-989

Sobolewski, A. L., Domcke, W., On the Mechanism of Nonradiative Decay of DNA Bases: Ab initio and TDDFT Results for the Excited States of 9H-Adenine (2002) Eur. Phys. J. D, 20, pp. 369-374

Bensasson, R. V., Land, E. J., Truscott, T. G., (1993) Excited States and Free Radicals in Biology and Medicine, , Oxford University Press: Oxford, U. K

Hare, P. M., Middleton, C. T., Mertel, K. I., Herbert, J. M., Kohler, B., Time-Resolved Infrared Spectroscopy of the Lowest Triplet State of Thymine and Thymidine (2008) Chem. Phys., 347, pp. 383-392

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2 Records (2 escludendo Abstract e Conferenze).
Impact factor totale: 7.761 (7.761 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 7.557 (7.557 escludendo Abstract e Conferenze).

Interrogazione bibliografica effettuata: (([btitle] "Building Blockes" OR [btitle] "Conical Intersection" OR [btitle] "Environmental Factors" OR [btitle] "Nonradiative Decays" OR [btitle] "Nucleic Acid Basis") AND NOT [id] = 8876)







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