Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: physico-chemical characterization (489 views visite)
Soft Matter (ISSN: 1744-683x), 2009; 5(13): 2504-2512.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 4.869, 5-year impact factor Impact factor a 5 anni: 5.415
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-70349290629&partnerID=40&md5=8d7947e63d6c2f22ebe86bbfee392529
Keywords Parole chiave: Amphiphilic Molecules, Colloidal Particle, Contrast Agent, Gadolinium Complexes, Gene Delivery, Medical Diagnostics, Physico-Chemical Characterization, Supramolecular Aggregates, Surfactant Aggregation, Amines, Gene Transfer, Magnetic Resonance Imaging, Peptides, Supramolecular Chemistry, Surface Active Agents, Tumors,
Affiliations Affiliazioni:
*** IBB - CNR ***
Dipartimento di Chimica, Università Degli Studi di Napoli Federico II, SGI Consorzio Interuniversitario per Lo Sviluppo Dei Sistemi A Grande Interfase, Via Cinthia, 80126 Naples, Italy
Institut für Festkörperforsching Forschungszentrum Jülich, Jülich Centre for Neutron Science, Lichtenbergstraße 1, 85748 Garching bei München, Germany
Physical Chemistry 1, Center for Chemistry and Chemical Engineering, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden
Dipartimento di Scienze Biologiche and CIRPeB, Via Mezzocannone 16, 80134 Naples, Italy
Institut f r Festk rperforsching Forschungszentrum J lich, J lich Centre for Neutron Science, Lichtenbergstra e 1, 85748 Garching bei M nchen, Germany
References Riferimenti:
Caravan, P., Ellison, J., McMurry, T., Lauffer, R., (1999) Chem Rev, 99, pp. 2293-235
Meade, T.J., Taylor, A.K., Bull, S.R., (2003) Curr. Opin. Neurobiol., 13, pp. 597-602
Bulte, J.W.M., Kraitchman, D.L., (2004) NMR Biomed., 17, pp. 484-499
Laurent, S., Forge, D., Port, M., Roch, A., Robic, C., Van Der Elst, L., Muller, R.N., (2008) Chemical Reviews, 108, pp. 2064-2110
Bloembergen, N., (1961) Journal of Chemical Physics, 34, pp. 842-850
Solomon, I., (1955) Physical Review, 99, pp. 559-565
Solomon, I., Bloembergen, N., (1956) Journal of Chemical Physics, 25, pp. 261-266
Laus, S., Sour, A., Ruloff, R., Toth, E., Merbach, A.E., (2005) Chem.-Eur. J., 11, pp. 3064-3076
Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J.S., Chin, S.-F., Gao, J., (2006) Nano Lett., 6, pp. 2427-2430
Dirksen, A., Langereis, S., De Waal, B.F.M., Van Genderen, M.H.P., Hackeng, T.M., Meijer, E.W., (2005) Chem. Commun., pp. 2811-2813
Toth, E., Bolskar, R.D., Borel, A., Gonzalez, G., Helm, L., Merbach, A.E., Sitharaman, B., Wilson, L.J., (2005) J. Am. Chem. Soc., 127, pp. 799-805
Accardo, A., Tesauro, D., Roscigno, P., Gianolio, E., Paduano, L., D'Errico, G., Pedone, C., Morelli, G., (2004) J. Am. Chem. Soc., 126, pp. 3097-3107
Glogard, C., Stensrud, G., Hovland, R., Fossheim, S.L., Klaveness, J., (2002) Int. J. Pharm., 233, pp. 131-140
Li King, C.P., Bednarski Mark, D., (2002) J Magn Reson Imaging, 16, pp. 388-393
Nasongkla, N., Shuai, X., Ai, H., Weinberg, B.D., Pink, J., Boothman, D.A., Gao, J., (2004) Angew. Chem., Int. Ed., 43, pp. 6323-6327
Reubi, J.C., (2003) Endocr. Rev., 24, pp. 389-427
Mulder, W.J.M., Strijkers, G.J., Griffioen, A.W., Van Bloois, L., Molema, G., Storm, G., Koning, G.A., Nicolay, K., (2004) Bioconjugate Chem. FIELD Full Journal Title:Bioconjugate Chemistry, 15, pp. 799-806
Sipkins, D.A., Cheresh, D.A., Kazemi, M.R., Nevin, L.M., Bednarski, M.D., Li, K.C.P., (1998) Nat. Med. (N.Y.,) FIELD Full Journal Title: Nature Medicine (New York), 4, pp. 623-626
Lobo, E.D., Hansen, R.J., Balthasar, J.P., (2004) Journal of Pharmaceutical Sciences, 93, pp. 2645-2668
Mulder, W.J.M., Van Der Schaft, D.W.J., Hautvast, P.A.I., Strijkers, G.J., Koning, G.A., Storm, G., Mayo, K.H., Nicolay, K., (2007) FASEB J. FIELD Full Journal Title:FASEB Journal, 21, pp. 378-383
Wank, S., (1995) Am. J. Physiol., 269, pp. 628-646
Mierke, D., Giragossian, C., (2001) Medicinal Research Reviews, 21, pp. 450-471
Reubi, J., Jc, S., Waser, B., (1997) Cancer Res, 57, pp. 1377-1386
Bull, S.R., Guler, M.O., Bras, R.E., Meade, T.J., Stupp, S.I., (2005) Nano Letters, 5, pp. 1-4
Mangiapia, G., Accardo, A., Lo Celso, F., Tesauro, D., Morelli, G., Radulescu, A., Paduano, L., (2004) J. Phys. Chem. B, 108, pp. 17611-17617
Andre Eva, J.P.T., Holger, F., Anna, S., MacKe Helmut, R., Merbach Andre, E., (1999) Chemistry-A European Journal, 5, pp. 2977-2983
Nicolle Eva, G.M.T., Klaus-Peter, E., MacKe Helmut, R., Merbach Andre, E., (2002) Journal of Biological Inorganic Chemistry, 7, pp. 757-769
Torres, S.M., Jose, A., Andre Joao, P., Geraldes Carlos, F.G.C., Merbach Andre, E., Toth, E., (2006) Chemistry-A European Journal, 12, pp. 940-948
Hovland, R.G., Christian, Aasen Arne, J., Jo, K., (2003) Organic & Biomolecular Chemistry, 1, pp. 644-647
Vaccaro, M., Accardo, A., Tesauro, D., Mangiapia, G., Loef, D., Schillen, K., Soederman, O., Paduano, L., (2006) Langmuir, 22, pp. 6635-6643
Jonstroemer, M., Joensson, B., Lindman, B., (1991) J. Phys. Chem., 95, pp. 3293-3300
Durham, E.J., Ryskiewich, D.P., (1958) J. Am. Chem. Soc., 80, pp. 4812-4817
Lichtenberg, D., Robson, R.J., Dennis, E.A., (1983) Biochim Biophys Acta, 737, pp. 285-304
Lichtenberg, D., (1985) Biochim Biophys Acta, 821, pp. 470-478
Johnsson, M., Hansson, P., Edwards, K., (2001) J. Phys. Chem. B, 105, pp. 8420-8430
Vaccaro, M., Mangiapia, G., Paduano, L., Gianolio, E., Accardo, A., Tesauro, D., Morelli, G., (2007) ChemPhysChem, 8, pp. 2526-2538
Parac-Vogt, T.N.K., Kristof, Laurent, S., Pierart, C., Vander Elst, L., Muller Robert, N., Koen, B., (2004) European Journal of Inorganic Chemistry, 17, pp. 3538-3543
Kimpe, K.P.-V., Tatjana, N., Sophie, L., Corinne, P., Vander Elst, L., Muller Robert, N., Koen, B., (2003) European Journal of Inorganic Chemistry, 16, pp. 3021-3027
Langereis, S., Kooistra, H.A.T., Van Genderen, M.H.P., Meijer, E.W., (2004) Org. Biomol. Chem., 2, pp. 1271-1273
Meade, T. J., Taylor, A. K., Bull, S. R., (2003) Curr. Opin. Neurobiol., 13, pp. 597-602
Bulte, J. W. M., Kraitchman, D. L., (2004) NMR Biomed., 17, pp. 484-499
Li King, C. P., Bednarski Mark, D., (2002) J Magn Reson Imaging, 16, pp. 388-393
Reubi, J. C., (2003) Endocr. Rev., 24, pp. 389-427
Mulder, W. J. M., Strijkers, G. J., Griffioen, A. W., Van Bloois, L., Molema, G., Storm, G., Koning, G. A., Nicolay, K., (2004) Bioconjugate Chem. FIELD Full Journal Title: Bioconjugate Chemistry, 15, pp. 799-806
Sipkins, D. A., Cheresh, D. A., Kazemi, M. R., Nevin, L. M., Bednarski, M. D., Li, K. C. P., (1998) Nat. Med. (N. Y.,) FIELD Full Journal Title: Nature Medicine (New York), 4, pp. 623-626
Lobo, E. D., Hansen, R. J., Balthasar, J. P., (2004) Journal of Pharmaceutical Sciences, 93, pp. 2645-2668
Mulder, W. J. M., Van Der Schaft, D. W. J., Hautvast, P. A. I., Strijkers, G. J., Koning, G. A., Storm, G., Mayo, K. H., Nicolay, K., (2007) FASEB J. FIELD Full Journal Title: FASEB Journal, 21, pp. 378-383
Bull, S. R., Guler, M. O., Bras, R. E., Meade, T. J., Stupp, S. I., (2005) Nano Letters, 5, pp. 1-4
Andre Eva, J. P. T., Holger, F., Anna, S., MacKe Helmut, R., Merbach Andre, E., (1999) Chemistry-A European Journal, 5, pp. 2977-2983
Nicolle Eva, G. M. T., Klaus-Peter, E., MacKe Helmut, R., Merbach Andre, E., (2002) Journal of Biological Inorganic Chemistry, 7, pp. 757-769
Torres, S. M., Jose, A., Andre Joao, P., Geraldes Carlos, F. G. C., Merbach Andre, E., Toth, E., (2006) Chemistry-A European Journal, 12, pp. 940-948
Hovland, R. G., Christian, Aasen Arne, J., Jo, K., (2003) Organic & Biomolecular Chemistry, 1, pp. 644-647
Durham, E. J., Ryskiewich, D. P., (1958) J. Am. Chem. Soc., 80, pp. 4812-4817
Parac-Vogt, T. N. K., Kristof, Laurent, S., Pierart, C., Vander Elst, L., Muller Robert, N., Koen, B., (2004) European Journal of Inorganic Chemistry, 17, pp. 3538-3543
Kimpe, K. P. -V., Tatjana, N., Sophie, L., Corinne, P., Vander Elst, L., Muller Robert, N., Koen, B., (2003) European Journal of Inorganic Chemistry, 16, pp. 3021-3027
Soft Matter (ISSN: 1744-683x), 2009; 5(13): 2504-2512.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 4.869, 5-year impact factor Impact factor a 5 anni: 5.415
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-70349290629&partnerID=40&md5=8d7947e63d6c2f22ebe86bbfee392529
Keywords Parole chiave: Amphiphilic Molecules, Colloidal Particle, Contrast Agent, Gadolinium Complexes, Gene Delivery, Medical Diagnostics, Physico-Chemical Characterization, Supramolecular Aggregates, Surfactant Aggregation, Amines, Gene Transfer, Magnetic Resonance Imaging, Peptides, Supramolecular Chemistry, Surface Active Agents, Tumors,
Affiliations Affiliazioni:
*** IBB - CNR ***
Dipartimento di Chimica, Università Degli Studi di Napoli Federico II, SGI Consorzio Interuniversitario per Lo Sviluppo Dei Sistemi A Grande Interfase, Via Cinthia, 80126 Naples, Italy
Institut für Festkörperforsching Forschungszentrum Jülich, Jülich Centre for Neutron Science, Lichtenbergstraße 1, 85748 Garching bei München, Germany
Physical Chemistry 1, Center for Chemistry and Chemical Engineering, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden
Dipartimento di Scienze Biologiche and CIRPeB, Via Mezzocannone 16, 80134 Naples, Italy
Institut f r Festk rperforsching Forschungszentrum J lich, J lich Centre for Neutron Science, Lichtenbergstra e 1, 85748 Garching bei M nchen, Germany
References Riferimenti:
Caravan, P., Ellison, J., McMurry, T., Lauffer, R., (1999) Chem Rev, 99, pp. 2293-235
Meade, T.J., Taylor, A.K., Bull, S.R., (2003) Curr. Opin. Neurobiol., 13, pp. 597-602
Bulte, J.W.M., Kraitchman, D.L., (2004) NMR Biomed., 17, pp. 484-499
Laurent, S., Forge, D., Port, M., Roch, A., Robic, C., Van Der Elst, L., Muller, R.N., (2008) Chemical Reviews, 108, pp. 2064-2110
Bloembergen, N., (1961) Journal of Chemical Physics, 34, pp. 842-850
Solomon, I., (1955) Physical Review, 99, pp. 559-565
Solomon, I., Bloembergen, N., (1956) Journal of Chemical Physics, 25, pp. 261-266
Laus, S., Sour, A., Ruloff, R., Toth, E., Merbach, A.E., (2005) Chem.-Eur. J., 11, pp. 3064-3076
Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J.S., Chin, S.-F., Gao, J., (2006) Nano Lett., 6, pp. 2427-2430
Dirksen, A., Langereis, S., De Waal, B.F.M., Van Genderen, M.H.P., Hackeng, T.M., Meijer, E.W., (2005) Chem. Commun., pp. 2811-2813
Toth, E., Bolskar, R.D., Borel, A., Gonzalez, G., Helm, L., Merbach, A.E., Sitharaman, B., Wilson, L.J., (2005) J. Am. Chem. Soc., 127, pp. 799-805
Accardo, A., Tesauro, D., Roscigno, P., Gianolio, E., Paduano, L., D'Errico, G., Pedone, C., Morelli, G., (2004) J. Am. Chem. Soc., 126, pp. 3097-3107
Glogard, C., Stensrud, G., Hovland, R., Fossheim, S.L., Klaveness, J., (2002) Int. J. Pharm., 233, pp. 131-140
Li King, C.P., Bednarski Mark, D., (2002) J Magn Reson Imaging, 16, pp. 388-393
Nasongkla, N., Shuai, X., Ai, H., Weinberg, B.D., Pink, J., Boothman, D.A., Gao, J., (2004) Angew. Chem., Int. Ed., 43, pp. 6323-6327
Reubi, J.C., (2003) Endocr. Rev., 24, pp. 389-427
Mulder, W.J.M., Strijkers, G.J., Griffioen, A.W., Van Bloois, L., Molema, G., Storm, G., Koning, G.A., Nicolay, K., (2004) Bioconjugate Chem. FIELD Full Journal Title:Bioconjugate Chemistry, 15, pp. 799-806
Sipkins, D.A., Cheresh, D.A., Kazemi, M.R., Nevin, L.M., Bednarski, M.D., Li, K.C.P., (1998) Nat. Med. (N.Y.,) FIELD Full Journal Title: Nature Medicine (New York), 4, pp. 623-626
Lobo, E.D., Hansen, R.J., Balthasar, J.P., (2004) Journal of Pharmaceutical Sciences, 93, pp. 2645-2668
Mulder, W.J.M., Van Der Schaft, D.W.J., Hautvast, P.A.I., Strijkers, G.J., Koning, G.A., Storm, G., Mayo, K.H., Nicolay, K., (2007) FASEB J. FIELD Full Journal Title:FASEB Journal, 21, pp. 378-383
Wank, S., (1995) Am. J. Physiol., 269, pp. 628-646
Mierke, D., Giragossian, C., (2001) Medicinal Research Reviews, 21, pp. 450-471
Reubi, J., Jc, S., Waser, B., (1997) Cancer Res, 57, pp. 1377-1386
Bull, S.R., Guler, M.O., Bras, R.E., Meade, T.J., Stupp, S.I., (2005) Nano Letters, 5, pp. 1-4
Mangiapia, G., Accardo, A., Lo Celso, F., Tesauro, D., Morelli, G., Radulescu, A., Paduano, L., (2004) J. Phys. Chem. B, 108, pp. 17611-17617
Andre Eva, J.P.T., Holger, F., Anna, S., MacKe Helmut, R., Merbach Andre, E., (1999) Chemistry-A European Journal, 5, pp. 2977-2983
Nicolle Eva, G.M.T., Klaus-Peter, E., MacKe Helmut, R., Merbach Andre, E., (2002) Journal of Biological Inorganic Chemistry, 7, pp. 757-769
Torres, S.M., Jose, A., Andre Joao, P., Geraldes Carlos, F.G.C., Merbach Andre, E., Toth, E., (2006) Chemistry-A European Journal, 12, pp. 940-948
Hovland, R.G., Christian, Aasen Arne, J., Jo, K., (2003) Organic & Biomolecular Chemistry, 1, pp. 644-647
Vaccaro, M., Accardo, A., Tesauro, D., Mangiapia, G., Loef, D., Schillen, K., Soederman, O., Paduano, L., (2006) Langmuir, 22, pp. 6635-6643
Jonstroemer, M., Joensson, B., Lindman, B., (1991) J. Phys. Chem., 95, pp. 3293-3300
Durham, E.J., Ryskiewich, D.P., (1958) J. Am. Chem. Soc., 80, pp. 4812-4817
Lichtenberg, D., Robson, R.J., Dennis, E.A., (1983) Biochim Biophys Acta, 737, pp. 285-304
Lichtenberg, D., (1985) Biochim Biophys Acta, 821, pp. 470-478
Johnsson, M., Hansson, P., Edwards, K., (2001) J. Phys. Chem. B, 105, pp. 8420-8430
Vaccaro, M., Mangiapia, G., Paduano, L., Gianolio, E., Accardo, A., Tesauro, D., Morelli, G., (2007) ChemPhysChem, 8, pp. 2526-2538
Parac-Vogt, T.N.K., Kristof, Laurent, S., Pierart, C., Vander Elst, L., Muller Robert, N., Koen, B., (2004) European Journal of Inorganic Chemistry, 17, pp. 3538-3543
Kimpe, K.P.-V., Tatjana, N., Sophie, L., Corinne, P., Vander Elst, L., Muller Robert, N., Koen, B., (2003) European Journal of Inorganic Chemistry, 16, pp. 3021-3027
Langereis, S., Kooistra, H.A.T., Van Genderen, M.H.P., Meijer, E.W., (2004) Org. Biomol. Chem., 2, pp. 1271-1273
Meade, T. J., Taylor, A. K., Bull, S. R., (2003) Curr. Opin. Neurobiol., 13, pp. 597-602
Bulte, J. W. M., Kraitchman, D. L., (2004) NMR Biomed., 17, pp. 484-499
Li King, C. P., Bednarski Mark, D., (2002) J Magn Reson Imaging, 16, pp. 388-393
Reubi, J. C., (2003) Endocr. Rev., 24, pp. 389-427
Mulder, W. J. M., Strijkers, G. J., Griffioen, A. W., Van Bloois, L., Molema, G., Storm, G., Koning, G. A., Nicolay, K., (2004) Bioconjugate Chem. FIELD Full Journal Title: Bioconjugate Chemistry, 15, pp. 799-806
Sipkins, D. A., Cheresh, D. A., Kazemi, M. R., Nevin, L. M., Bednarski, M. D., Li, K. C. P., (1998) Nat. Med. (N. Y.,) FIELD Full Journal Title: Nature Medicine (New York), 4, pp. 623-626
Lobo, E. D., Hansen, R. J., Balthasar, J. P., (2004) Journal of Pharmaceutical Sciences, 93, pp. 2645-2668
Mulder, W. J. M., Van Der Schaft, D. W. J., Hautvast, P. A. I., Strijkers, G. J., Koning, G. A., Storm, G., Mayo, K. H., Nicolay, K., (2007) FASEB J. FIELD Full Journal Title: FASEB Journal, 21, pp. 378-383
Bull, S. R., Guler, M. O., Bras, R. E., Meade, T. J., Stupp, S. I., (2005) Nano Letters, 5, pp. 1-4
Andre Eva, J. P. T., Holger, F., Anna, S., MacKe Helmut, R., Merbach Andre, E., (1999) Chemistry-A European Journal, 5, pp. 2977-2983
Nicolle Eva, G. M. T., Klaus-Peter, E., MacKe Helmut, R., Merbach Andre, E., (2002) Journal of Biological Inorganic Chemistry, 7, pp. 757-769
Torres, S. M., Jose, A., Andre Joao, P., Geraldes Carlos, F. G. C., Merbach Andre, E., Toth, E., (2006) Chemistry-A European Journal, 12, pp. 940-948
Hovland, R. G., Christian, Aasen Arne, J., Jo, K., (2003) Organic & Biomolecular Chemistry, 1, pp. 644-647
Durham, E. J., Ryskiewich, D. P., (1958) J. Am. Chem. Soc., 80, pp. 4812-4817
Parac-Vogt, T. N. K., Kristof, Laurent, S., Pierart, C., Vander Elst, L., Muller Robert, N., Koen, B., (2004) European Journal of Inorganic Chemistry, 17, pp. 3538-3543
Kimpe, K. P. -V., Tatjana, N., Sophie, L., Corinne, P., Vander Elst, L., Muller Robert, N., Koen, B., (2003) European Journal of Inorganic Chemistry, 16, pp. 3021-3027
Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: physico-chemical characterization
This article highlights our recent achievements on the development and upgrade of new potential tumor-specific contrast agents for magnetic resonance imaging (MRI) based on gadolinium complexes and peptides, assemblied in amphiphilic supramolecular aggregates. The physico-chemical characterization of these aggregates provides novel and interesting opportunities to investigate surfactant aggregation properties, that may be exploited in several applications such as in medical diagnostics or in drug and gene delivery.
This article highlights our recent achievements on the development and upgrade of new potential tumor-specific contrast agents for magnetic resonance imaging (MRI) based on gadolinium complexes and peptides, assemblied in amphiphilic supramolecular aggregates. The physico-chemical characterization of these aggregates provides novel and interesting opportunities to investigate surfactant aggregation properties, that may be exploited in several applications such as in medical diagnostics or in drug and gene delivery.
Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: physico-chemical characterization
| ▼ MRI Tracking of Macrophages Labeled with Glucan Particles Entrapping perfluorocarbons based nanoparticles |
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Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: physico-chemical characterization
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* MRI features suggestive of gadolinium retention do not correlate with Expanded Disability Status Scale worsening in Multiple Sclerosis (267 visite)
Neuroradiology (ISSN: 0028-3940linking, 1432-1920electronic), 2019 Feb; 61(2): 155-162.
Impact Factor: 1.287
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Baroni S, Ruggiero MR, Aime S, Geninatti Crich S
* Exploring the tumour extracellular matrix by in vivo Fast Field Cycling relaxometry after the administration of a Gadolinium-based MRI contrast agent (232 visite)
Magn Reson Chem (ISSN: 0749-1581linking), 2019 Jan 24; N/D: N/D-N/D.
Impact Factor: 1.601
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Dastru W, Menchise V, Ferrauto G, Fabretto S, Carrera C, Terreno E, Aime S, Delli Castelli D
* Modulation of the Prototropic Exchange Rate in pH-Responsive Yb-HPDO3A Derivatives as ParaCEST Agents (193 visite)
Chemistryselect (ISSN: 2365-6549), 2018 Jun; 3(22): 6035-6041.
Impact Factor: 1.505
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Gianolio E, Bardini P, Arena F, Stefania R, Di Gregorio E, Iani R, Aime S
* Gadolinium Retention in the Rat Brain: Assessment of the Amounts of Insoluble Gadolinium-containing Species and Intact Gadolinium Complexes after Repeated Administration of Gadolinium-based Contrast Agents (270 visite)
Radiology (ISSN: 0033-8419, 1527-1315), 2017 Dec; 285(3): 839-849.
Impact Factor: 7.469
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Srivastava K, Ferrauto G, Young Vg J, Aime S, Pierre VC
* Eight-Coordinate, Stable Fe(II) Complex as a Dual (19)F and CEST Contrast Agent for Ratiometric pH Imaging (163 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2017 Oct 16; 56(20): 12206-12213.
Impact Factor: 4.7
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Longo DL, Stefania R, Aime S, Oraevsky A
* Melanin-Based Contrast Agents for Biomedical Optoacoustic Imaging and Theranostic Applications (252 visite)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2017 Aug 7; 18(8): N/D-N/D.
Impact Factor: 3.687
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Longo DL, Moustaghfir FZ, Zerbo A, Consolino L, Anemone A, Bracesco M, Aime S
* EXCI-CEST: Exploiting pharmaceutical excipients as MRI-CEST contrast agents for tumor imaging (323 visite)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2017; 525(1): 275-281.
Impact Factor: 3.862
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Anemone A, Consolino L, Longo DL
* MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent (149 visite)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic), 2017; 27(5): 2170-2179.
Impact Factor: 4.027
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Consolino L, Longo DL, Sciortino M, Dastru W, Cabodi S, Giovenzana GB, Aime S
* Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging (238 visite)
Gastric Cancer (ISSN: 1436-3291, 1436-3291linking), 2016 Dec 19; 20(4): 629-639.
Impact Factor: 5.454
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Tedeschi E, Palma G, Canna A, Cocozza S, Russo C, Borrelli P, Lanzillo R, Angelini V, Postiglione E, Morra VB, Salvatore M, Brunetti A, Quarantelli M
* In vivo dentate nucleus MRI relaxometry correlates with previous administration of Gadolinium-based contrast agents (385 visite)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic), 2016 Feb 23; 26(12): 4577-4584.
Impact Factor: 3.967
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Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (408 visite)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
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Consolino L, Longo DL, Dastrù W, Cutrin JC, Dettori D, Lanzardo S, Oliviero S, Cavallo F, Aime S
* Functional imaging of the angiogenic switch in a transgenic mouse model of human breast cancer by dynamic contrast enhanced magnetic resonance imaging (270 visite)
Int J Cancer (ISSN: 0020-7136), 2016; N/D: N/D-N/D.
Impact Factor: 6.513
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Longo DL, Arena F, Consolino L, Minazzi P, Geninatti-crich S, Giovenzana GB, Aime S
* Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners (371 visite)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2015 Oct 16; 75: 47-57.
Impact Factor: 8.387
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Delli Castelli D, Ferrauto G, Di Gregorio E, Terreno E, Aime S
* Sensitive MRI detection of internalized T contrast agents using magnetization transfer contrast (221 visite)
Nmr Biomed (ISSN: 0952-3480, 1099-1492electronic), 2015 Oct 16; N/D: N/D-N/D.
Impact Factor: 2.983
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Longo DL, Michelotti F, Consolino L, Bardini P, Digilio G, Xiao G, Sun PZ, Aime S
* In Vitro and In Vivo Assessment of Nonionic Iodinated Radiographic Molecules as Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Tumor Perfusion Agents (255 visite)
Invest Radiol (ISSN: 0020-9996, 1536-0210, 1536-0210electronic), 2015 Oct 12; 51(3): 155-162.
Impact Factor: 4.887
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Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (402 visite)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
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Accardo A, Ringhieri P, Palumbo R, Morelli G
* Influence of PEG length on conformational and binding properties of CCK peptides exposed by supramolecular aggregates (363 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Apr; 101(4): 304-312.
Impact Factor: 2.385
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Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (514 visite)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
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Pica A, Merlino A, Buell AK, Knowles TJ, Pizzo E, D'Alessio G, Sica F, Mazzarella L
* Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase (845 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Oct; 69: 2116-2123.
Impact Factor: 7.232
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Mancini M, Greco A, Salvatore G, Liuzzi R, Di Maro G, Vergara E, Chiappetta G, Pasquinelli R, Brunetti A, Salvatore M
* Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice (437 visite)
Bmc Med Imaging (ISSN: 1471-2342, 1471-2342electronic), 2013 Sep 12; 13(1): 31-31.
Impact Factor: 0.983
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Nande R, Greco A, Gossman MS, Lopez JP, Claudio L, Salvatore M, Brunetti A, Denvir J, Howard CM, Claudio PP
* Microbubble-assisted p53, RB, and p130 gene transfer in combination with radiation therapy in prostate cancer (412 visite)
Current Gene Therapy (ISSN: 1875-5631, 1566-5232), 2013 Jun 1; 13(3): 163-174.
Impact Factor: 4.906
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Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (362 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
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Mancini M, Di Donato O, Saldalamacchia G, Liuzzi R, Rivellese A, Salvatore M
* Contrast-enhanced ultrasound evaluation of peripheral microcirculation in diabetic patients: effects of cigarette smoking (363 visite)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 2013 Mar; 118(2): 206-214.
Impact Factor: 1.368
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Accardo A, Gianolio E, Arena F, Barnert S, Schubert R, Tesauro D, Morelli G
* Nanostructures based on monoolein or diolein and amphiphilic gadolinium complexes as MRI contrast agents (374 visite)
J Mater Chem B (ISSN: 2050-7518, 2050-750x), 2013; 1(5): 617-628.
Impact Factor: 8.535
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Gringeri CV, Menchise V, Rizzitelli S, Cittadino E, Catanzaro V, Dati G, Chaabane L, Digilio G, Aime S
* Novel Gd(III)-based probes for MR molecular imaging of matrix metalloproteinases (445 visite)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2012 Mar; 7(2): 175-184.
Impact Factor: 2.872
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Menchise V, Digilio G, Gianolio E, Cittadino E, Catanzaro V, Carrera C, Aime S
* MR Contrast Agents (307 visite)
Mol Pharm (ISSN: 1543-8384), 2011 Sep; 8(5): 1750-1756.
Impact Factor: 4.782
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Malvindi MA, Greco A, Conversano F, Figuerola A, Corti M, Bonora M, Lascialfari A, Doumari HA, Moscardini M, Cingolani R, Gigli G, Casciaro S, Pellegrino T, Ragusa A
* MR Contrast Agents (262 visite)
Small Animal Imaging, 2011 Jul 8; 21(13): 2548-2555.
Impact Factor: 1.784
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Terreno E, Boffa C, Menchise V, Fedeli F, Carrera C, Castelli DD, Digilio G, Aime S
* Gadolinium-doped LipoCEST agents: A potential novel class of dual 1H-MRI probes (322 visite)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2011 Apr 28; 47(16): 4667-4669.
Impact Factor: 6.169
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Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (501 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
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Accardo A, Morisco A, Palladino P, Palumbo R, Tesauro D, Morelli G
* Amphiphilic CCK peptides assembled in supramolecular aggregates: Structural investigations and in vitro studies (460 visite)
Mol Biosyst (ISSN: 1742-206x), 2011 Mar; 7(3): 862-870.
Impact Factor: 3.534
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Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (464 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 Feb; 17(2): 154-162.
Impact Factor: 1.799
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Menchise V, Digilio G, Gianolio E, Cittadino E, Catanzaro V, Carrera C, Aime S
* In vivo labeling of B16 melanoma tumor xenograft with a thiol-reactive gadolinium based MRI contrast agent (400 visite)
Mol Pharm (ISSN: 1543-8384), 2011; 8(5): 1750-1756.
Impact Factor: 4.782
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Morisco A, Accardo A, Tesauro D, Palumbo R, Benedetti E, Morelli G
* Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (346 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011; 96(1): 88-96.
Impact Factor: 2.87
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Mainenti PP, Mancini M, Mainolfi C, Camera L, Maurea S, Manchia A, Tanga M, Persico F, Addeo P, D'Antonio D, Speranza A, Bucci L, Persico G, Pace L, Salvatore M
* Detection of colo-rectal liver metastases: Prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1. 5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents (373 visite)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2010 Oct; 35(5): 511-521.
Impact Factor: 1.95
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Orsi S, De Capua A, Guarnieri D, Marasco D, Netti PA
* Cell recruitment and transfection in gene activated collagen matrix (350 visite)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2010 Jan; 31(3): 570-576.
Impact Factor: 7.883
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Moccia M, Musumeci D, Roviello GN, Fusco S, Valente M, Bucci EM, Sapio R, Pedonea C, Netti PA
* Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks (590 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Oct; 15(10): 647-653.
Impact Factor: 1.807
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Accardo A, Tesauro D, Aloj L, Pedone C, Morelli G
* Supramolecular aggregates containing lipophilic Gd(III) complexes as contrast agents in MRI (496 visite)
Coord Chem Rev (ISSN: 0010-8545), 2009 Sep; 253(17-18): 2193-2213.
Impact Factor: 11.225
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Mancini M, Greco A, Speranza A, Salvatore M
* Ultrasound molecular imaging by targeted microbubble contrast agents (364 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Jun; 21(2): 97-110.
Impact Factor: 0.268
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Accardo A, Tesauro D, Morisco A, Mangiapia G, Vaccaro M, Gianolio E, Heenan RK, Paduano L, Morelli G
* Micelles obtained by aggregation of gemini surfactants containing the CCK8 peptide and a gadolinium complex (379 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257linking), 2009 May; 14(4): 587-599.
Impact Factor: 3.415
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Garzia L, Andolfo I, Cusanelli E, Marino N, Petrosino G, De Martino D, Esposito V, Galeone A, Navas L, Esposito S, Gargiulo S, Fattet S, Donofrio V, Cinalli G, Brunetti A, Del Vecchio L, Northcott PA, Delattre O, Taylor MD, Iolascon A, Zollo M
* MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma (415 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2009 Mar 24; 4(3): e4998-e4998.
Impact Factor: 4.351
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Morisco A, Accardo A, Gianolio E, Tesauro D, Benedetti E, Morelli G
* Micelles derivatized with octreotide as potential target-selective contrast agents in MRI (337 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 242-250.
Impact Factor: 1.807
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Sorriento D, Campanile A, Santulli G, Leggiero E, Pastore L, Trimarco B, Iaccarino G
* A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity (336 visite)
Mol Cancermolecular Cancer (ISSN: 1476-4598), 2009; 8: N/D-N/D.
Impact Factor: 4.16
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Mancini M, Speranza A, Greco A, Salvatore M
* Effects Of High Frequency Ultrasound On Echogenicity Of Ultrasound Contrast Agents Solutions (222 visite)
Endocrinology, 2009; 35(8S): 221-221.
Impact Factor: 4.503
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Accardo A, Tesauro D, Morelli G, Del Pozzo L, Pedone C, Tornesello AL, Benedetti E
* Supramolecular aggregates derivatized by CCK8 peptide as selective nanocarriers for drug delivery (339 visite)
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print), 2009; 611: 603-604.
Impact Factor: 2.02
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Vaccaro M, Mangiapia G, Accardo A, Tesauro D, Gianolio E, Frielinghaus H, Morelli G, Paduano L
* Polymerized mixed aggregates containing gadolinium complex and CCK8 peptide (339 visite)
Colloid Polym Sci (ISSN: 0303-402x), 2008 Dec; 286(14-15): 1643-1652.
Impact Factor: 1.736
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Accardo A, Tesauro D, Benedetti E, Pedone C, Morelli G
* Naposomes: A new class of peptide containing supramolecular aggregates as target selective delivery systems (226 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
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Accardo A, Tesauro D, Aloj L, Tarallo L, Arra C, Mangiapia G, Vaccaro M, Pedone C, Paduano L, Morelli G
* Peptide-containing aggregates as selective nanocarriers for therapeutics (348 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2008 Apr; 3(4): 594-602.
Impact Factor: 3.15
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Breveglieri G, Pensato S, Salvatori F, Saviano M, Pedone C, Romanelli A, Gambari R
* PNA-mediated alteration of mRNA splicing (309 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 175-181.
Impact Factor: 0.1
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Vaccaro M, Mangiapia G, Paduano L, Gianolio E, Accardo A, Tesauro D, Morelli G
* Structural and relaxometric characterization of peptide aggregates containing gadolinium complexes as potential selective contrast agents in MRI (535 visite)
Chemphyschem (ISSN: 1439-4235, 1439-7641, 1439-7641electronic), 2007 Dec 3; 8(17): 2526-2538.
Impact Factor: 3.502
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Vaccaro M, Accardo A, D'Errico G, Schillen K, Radulescu A, Tesauro D, Morelli G, Paduano L
* Peptides and gd complexes containing colloidal assemblies as tumor-specific contrast agents in MRI: Physicochemical characterization (374 visite)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2007 Sep; 93(5): 1736-1746.
Impact Factor: 4.627
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Tesauro D, Accardo A, Gianolio E, Paduano L, Teixeira J, Schillén K, Aime S, Morelli G
* Peptide derivatized lamellar aggregates as target-specific MRI contrast agents (418 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 25; 8(8): 950-955.
Impact Factor: 3.446
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Accardo A, Tesauro D, Morelli G, Gianolio E, Aime S, Vaccaro M, Mangiapia G, Paduano L, Schillén K
* High-relaxivity supramolecular aggregates containing peptides and Gd complexes as contrast agents in MRI (383 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2007 Feb; 12(2): 267-276.
Impact Factor: 3.325
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Mainenti PP, Cirillo LC, Camera L, Persico F, Cantalupo T, Pace L, De Palma GD, Persico G, Salvatore M
* Accuracy of single phase contrast enhanced multidetector CT colonography in the preoperative staging of colo-rectal cancer (297 visite)
Eur J Radiol (ISSN: 0720-048x), 2006 Dec; 60(3): 453-459.
Impact Factor: 1.332
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Vaccaro M, Accardo A, Tesauro D, Mangiapia G, Loef D, Schillen K, Soederman O, Morelli G, Paduan L
* Supramolecular aggregates of amphiphilic gadolinium complexes as blood pool MRI/MRA contrast agents: Physicochemical characterization (367 visite)
Langmuir (ISSN: 0743-7463), 2006 Jul 18; 22(15): 6635-6643.
Impact Factor: 3.902
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Cittadini A, Monti MG, Iaccarino G, Di Rella F, Tsichlis PN, Di Gianni A, Strömer H, Sorriento D, Peschle C, Trimarco B, Saccà L, Condorelli G
* Adenoviral gene transfer of Akt enhances myocardial contractility and intracellular calcium handling (518 visite)
Gene Ther (ISSN: 0969-7128, 0969-7128linking), 2006; 13(1): 8-19.
Impact Factor: 4.782
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Morelli G, Accardo A, Tesauro D, Pedone C, Mangiapia G, Paduano L, Gianolio E
* Multicomponent aggregates containing the CCK8 bioactive peptide and Gd complexes as target-specific MRI contrast agents (230 visite)
Peptides 2004 Proceedings, 2005; N/D: N/D-N/D.
Impact Factor: 0
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Accardo A, Tesauro D, Roscigno P, Gianolio E, Paduano L, D'Errico G, Pedone C, Morelli G
* Physicochemical Properties of Mixed Micellar Aggregates Containing CCK Peptides and Gd Complexes Designed as Tumor Specific Contrast Agents in MRI (421 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2004 Mar 17; 126(10): 3097-3107.
Impact Factor: 6.903
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Mangiapia G, Accardo A, Celso FL, Tesauro D, Morelli G, Radulescu A, Paduano L
* Mixed micelles composed of peptides and gadolinium complexes as tumor-specific contrast agents in MRI: A sans study (554 visite)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2004; 108(45): 17611-17617.
Impact Factor: 3.834
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Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R
* Cationic Liposomes As Delivery Systems For Double-Stranded Pna-Dna Chimeras Exhibiting Decoy Activity Against Nf-Kappab Transcription Factors (371 visite)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2002 Sep 15; 64(4): 609-616.
Impact Factor: 3.542
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69 Records (64 escludendo Abstract e Conferenze).
Impact factor totale: 252.843 (239.352 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 275.863 (261.704 escludendo Abstract e Conferenze).
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Consolino L, Irrera P, Romdhane F, Anemone A, Longo DL
* Investigating plasma volume expanders as novel macromolecular MRI-CEST contrast agents for tumor contrast-enhanced imaging (8 visite)
Magn Reson Med (ISSN: 0740-3194linking), 2021 Aug; 86(2): 995-1007.
Impact Factor: 3.635
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Garello F, Boido M, Miglietti M, Bitonto V, Zenzola M, Filippi M, Arena F, Consolino L, Ghibaudi M, Terreno E
* Imaging of Inflammation in Spinal Cord Injury: Novel Insights on the Usage of PFC-Based Contrast Agents (8 visite)
Biomedicines (ISSN: 2227-9059linking), 2021 Apr 3; 9(4): N/D-N/D.
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Baroni S, Stefania R, Broche LM, Senn N, Lurie DJ, Ross PJ, Aime S, Geninatti Crich S
* A Novel Class of (1) H-MRI Contrast Agents Based on the Relaxation Enhancement Induced on Water Protons by (14) N-Containing Imidazole Moieties (64 visite)
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Zöllner FG, Dastrù W, Irrera P, Longo DL, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR
* Analysis Protocol for Dynamic Contrast Enhanced (DCE) MRI of Renal Perfusion and Filtration (8 visite)
Methods Mol Biol (ISSN: 1064-3745linking), 2021; 2216: 637-653.
Impact Factor: 1.17
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Kim H, Wu Y, Villano D, Longo DL, Mcmahon MT, Sun PZ
* Analysis Protocol for the Quantification of Renal pH Using Chemical Exchange Saturation Transfer (CEST) MRI (8 visite)
Methods Mol Biol (ISSN: 1064-3745linking), 2021; 2216: 667-688.
Impact Factor: 1.17
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Irrera P, Consolino L, Dastrù W, Pedersen M, Zöllner FG, Longo DL
* Dynamic Contrast Enhanced (DCE) MRI-Derived Renal Perfusion and Filtration: Experimental Protocol (8 visite)
Methods Mol Biol (ISSN: 1064-3745linking), 2021; 2216: 429-441.
Impact Factor: 1.17
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Pedersen M, Irrera P, Dastrù W, Zöllner FG, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR, Longo DL
* Dynamic Contrast Enhancement (DCE) MRI-Derived Renal Perfusion and Filtration: Basic Concepts (9 visite)
Methods Mol Biol (ISSN: 1064-3745linking), 2021; 2216: 205-227.
Impact Factor: 1.17
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Pavuluri KD, Consolino L, Longo DL, Irrera P, Sun PZ, Mcmahon MT
* Renal pH Mapping Using Chemical Exchange Saturation Transfer (CEST) MRI: Experimental Protocol (8 visite)
Methods Mol Biol (ISSN: 1064-3745linking), 2021; 2216: 455-471.
Impact Factor: 1.17
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Tear LR, Carrera C, Gianolio E, Aime S
* Towards an Improved Design of MRI Contrast Agents: Synthesis and Relaxometric Characterisation of Gd-HPDO3A Analogues (54 visite)
Chemistry (ISSN: 0947-6539linking), 2020 May 12; 26(27): 6056-6063.
Impact Factor: 4.857
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Granato L, Longo D, Boutry S, Vander Elst L, Henoumont C, Aime S, Muller RN, Laurent S
* Synthesis and Relaxometric Characterization of New Poly[N, N-bis(3-aminopropyl)glycine] (PAPGly) Dendrons Gd-Based Contrast Agents and Their in Vivo Study by Using the Dynamic Contrast-Enhanced MRI Technique at Low Field (1 T) (118 visite)
Chem Biodivers (ISSN: 1612-1872linking), 2019 Nov; 16(11): e1900322-e1900322.
Impact Factor: 1.449
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Cocozza S, Pontillo G, Lanzillo R, Russo C, Petracca M, Di Stasi M, Paolella C, Vola EA, Criscuolo C, Moccia M, Lamberti A, Monti S, Brescia Morra V, Elefante A, Palma G, Tedeschi E, Brunetti A
* MRI features suggestive of gadolinium retention do not correlate with Expanded Disability Status Scale worsening in Multiple Sclerosis (267 visite)
Neuroradiology (ISSN: 0028-3940linking, 1432-1920electronic), 2019 Feb; 61(2): 155-162.
Impact Factor: 1.287
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Baroni S, Ruggiero MR, Aime S, Geninatti Crich S
* Exploring the tumour extracellular matrix by in vivo Fast Field Cycling relaxometry after the administration of a Gadolinium-based MRI contrast agent (232 visite)
Magn Reson Chem (ISSN: 0749-1581linking), 2019 Jan 24; N/D: N/D-N/D.
Impact Factor: 1.601
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Dastru W, Menchise V, Ferrauto G, Fabretto S, Carrera C, Terreno E, Aime S, Delli Castelli D
* Modulation of the Prototropic Exchange Rate in pH-Responsive Yb-HPDO3A Derivatives as ParaCEST Agents (193 visite)
Chemistryselect (ISSN: 2365-6549), 2018 Jun; 3(22): 6035-6041.
Impact Factor: 1.505
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Gianolio E, Bardini P, Arena F, Stefania R, Di Gregorio E, Iani R, Aime S
* Gadolinium Retention in the Rat Brain: Assessment of the Amounts of Insoluble Gadolinium-containing Species and Intact Gadolinium Complexes after Repeated Administration of Gadolinium-based Contrast Agents (270 visite)
Radiology (ISSN: 0033-8419, 1527-1315), 2017 Dec; 285(3): 839-849.
Impact Factor: 7.469
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Srivastava K, Ferrauto G, Young Vg J, Aime S, Pierre VC
* Eight-Coordinate, Stable Fe(II) Complex as a Dual (19)F and CEST Contrast Agent for Ratiometric pH Imaging (163 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2017 Oct 16; 56(20): 12206-12213.
Impact Factor: 4.7
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Longo DL, Stefania R, Aime S, Oraevsky A
* Melanin-Based Contrast Agents for Biomedical Optoacoustic Imaging and Theranostic Applications (252 visite)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2017 Aug 7; 18(8): N/D-N/D.
Impact Factor: 3.687
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Longo DL, Moustaghfir FZ, Zerbo A, Consolino L, Anemone A, Bracesco M, Aime S
* EXCI-CEST: Exploiting pharmaceutical excipients as MRI-CEST contrast agents for tumor imaging (323 visite)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2017; 525(1): 275-281.
Impact Factor: 3.862
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Anemone A, Consolino L, Longo DL
* MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent (149 visite)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic), 2017; 27(5): 2170-2179.
Impact Factor: 4.027
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Consolino L, Longo DL, Sciortino M, Dastru W, Cabodi S, Giovenzana GB, Aime S
* Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging (238 visite)
Gastric Cancer (ISSN: 1436-3291, 1436-3291linking), 2016 Dec 19; 20(4): 629-639.
Impact Factor: 5.454
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Tedeschi E, Palma G, Canna A, Cocozza S, Russo C, Borrelli P, Lanzillo R, Angelini V, Postiglione E, Morra VB, Salvatore M, Brunetti A, Quarantelli M
* In vivo dentate nucleus MRI relaxometry correlates with previous administration of Gadolinium-based contrast agents (385 visite)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic), 2016 Feb 23; 26(12): 4577-4584.
Impact Factor: 3.967
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Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (408 visite)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
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Consolino L, Longo DL, Dastrù W, Cutrin JC, Dettori D, Lanzardo S, Oliviero S, Cavallo F, Aime S
* Functional imaging of the angiogenic switch in a transgenic mouse model of human breast cancer by dynamic contrast enhanced magnetic resonance imaging (270 visite)
Int J Cancer (ISSN: 0020-7136), 2016; N/D: N/D-N/D.
Impact Factor: 6.513
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Longo DL, Arena F, Consolino L, Minazzi P, Geninatti-crich S, Giovenzana GB, Aime S
* Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners (371 visite)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2015 Oct 16; 75: 47-57.
Impact Factor: 8.387
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Delli Castelli D, Ferrauto G, Di Gregorio E, Terreno E, Aime S
* Sensitive MRI detection of internalized T contrast agents using magnetization transfer contrast (221 visite)
Nmr Biomed (ISSN: 0952-3480, 1099-1492electronic), 2015 Oct 16; N/D: N/D-N/D.
Impact Factor: 2.983
Dettagli Esporta in BibTeX Esporta in EndNote
Longo DL, Michelotti F, Consolino L, Bardini P, Digilio G, Xiao G, Sun PZ, Aime S
* In Vitro and In Vivo Assessment of Nonionic Iodinated Radiographic Molecules as Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Tumor Perfusion Agents (255 visite)
Invest Radiol (ISSN: 0020-9996, 1536-0210, 1536-0210electronic), 2015 Oct 12; 51(3): 155-162.
Impact Factor: 4.887
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Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (402 visite)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Ringhieri P, Palumbo R, Morelli G
* Influence of PEG length on conformational and binding properties of CCK peptides exposed by supramolecular aggregates (363 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Apr; 101(4): 304-312.
Impact Factor: 2.385
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Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (514 visite)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
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Pica A, Merlino A, Buell AK, Knowles TJ, Pizzo E, D'Alessio G, Sica F, Mazzarella L
* Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase (845 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Oct; 69: 2116-2123.
Impact Factor: 7.232
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Mancini M, Greco A, Salvatore G, Liuzzi R, Di Maro G, Vergara E, Chiappetta G, Pasquinelli R, Brunetti A, Salvatore M
* Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice (437 visite)
Bmc Med Imaging (ISSN: 1471-2342, 1471-2342electronic), 2013 Sep 12; 13(1): 31-31.
Impact Factor: 0.983
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Nande R, Greco A, Gossman MS, Lopez JP, Claudio L, Salvatore M, Brunetti A, Denvir J, Howard CM, Claudio PP
* Microbubble-assisted p53, RB, and p130 gene transfer in combination with radiation therapy in prostate cancer (412 visite)
Current Gene Therapy (ISSN: 1875-5631, 1566-5232), 2013 Jun 1; 13(3): 163-174.
Impact Factor: 4.906
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Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (362 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
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Mancini M, Di Donato O, Saldalamacchia G, Liuzzi R, Rivellese A, Salvatore M
* Contrast-enhanced ultrasound evaluation of peripheral microcirculation in diabetic patients: effects of cigarette smoking (363 visite)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 2013 Mar; 118(2): 206-214.
Impact Factor: 1.368
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Accardo A, Gianolio E, Arena F, Barnert S, Schubert R, Tesauro D, Morelli G
* Nanostructures based on monoolein or diolein and amphiphilic gadolinium complexes as MRI contrast agents (374 visite)
J Mater Chem B (ISSN: 2050-7518, 2050-750x), 2013; 1(5): 617-628.
Impact Factor: 8.535
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Gringeri CV, Menchise V, Rizzitelli S, Cittadino E, Catanzaro V, Dati G, Chaabane L, Digilio G, Aime S
* Novel Gd(III)-based probes for MR molecular imaging of matrix metalloproteinases (445 visite)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2012 Mar; 7(2): 175-184.
Impact Factor: 2.872
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Menchise V, Digilio G, Gianolio E, Cittadino E, Catanzaro V, Carrera C, Aime S
* MR Contrast Agents (307 visite)
Mol Pharm (ISSN: 1543-8384), 2011 Sep; 8(5): 1750-1756.
Impact Factor: 4.782
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Malvindi MA, Greco A, Conversano F, Figuerola A, Corti M, Bonora M, Lascialfari A, Doumari HA, Moscardini M, Cingolani R, Gigli G, Casciaro S, Pellegrino T, Ragusa A
* MR Contrast Agents (262 visite)
Small Animal Imaging, 2011 Jul 8; 21(13): 2548-2555.
Impact Factor: 1.784
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Terreno E, Boffa C, Menchise V, Fedeli F, Carrera C, Castelli DD, Digilio G, Aime S
* Gadolinium-doped LipoCEST agents: A potential novel class of dual 1H-MRI probes (322 visite)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2011 Apr 28; 47(16): 4667-4669.
Impact Factor: 6.169
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Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (501 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
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Accardo A, Morisco A, Palladino P, Palumbo R, Tesauro D, Morelli G
* Amphiphilic CCK peptides assembled in supramolecular aggregates: Structural investigations and in vitro studies (460 visite)
Mol Biosyst (ISSN: 1742-206x), 2011 Mar; 7(3): 862-870.
Impact Factor: 3.534
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Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (464 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 Feb; 17(2): 154-162.
Impact Factor: 1.799
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Menchise V, Digilio G, Gianolio E, Cittadino E, Catanzaro V, Carrera C, Aime S
* In vivo labeling of B16 melanoma tumor xenograft with a thiol-reactive gadolinium based MRI contrast agent (400 visite)
Mol Pharm (ISSN: 1543-8384), 2011; 8(5): 1750-1756.
Impact Factor: 4.782
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Morisco A, Accardo A, Tesauro D, Palumbo R, Benedetti E, Morelli G
* Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (346 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011; 96(1): 88-96.
Impact Factor: 2.87
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Mainenti PP, Mancini M, Mainolfi C, Camera L, Maurea S, Manchia A, Tanga M, Persico F, Addeo P, D'Antonio D, Speranza A, Bucci L, Persico G, Pace L, Salvatore M
* Detection of colo-rectal liver metastases: Prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1. 5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents (373 visite)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2010 Oct; 35(5): 511-521.
Impact Factor: 1.95
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Orsi S, De Capua A, Guarnieri D, Marasco D, Netti PA
* Cell recruitment and transfection in gene activated collagen matrix (350 visite)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2010 Jan; 31(3): 570-576.
Impact Factor: 7.883
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Moccia M, Musumeci D, Roviello GN, Fusco S, Valente M, Bucci EM, Sapio R, Pedonea C, Netti PA
* Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks (590 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Oct; 15(10): 647-653.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Tesauro D, Aloj L, Pedone C, Morelli G
* Supramolecular aggregates containing lipophilic Gd(III) complexes as contrast agents in MRI (496 visite)
Coord Chem Rev (ISSN: 0010-8545), 2009 Sep; 253(17-18): 2193-2213.
Impact Factor: 11.225
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Mancini M, Greco A, Speranza A, Salvatore M
* Ultrasound molecular imaging by targeted microbubble contrast agents (364 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Jun; 21(2): 97-110.
Impact Factor: 0.268
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Accardo A, Tesauro D, Morisco A, Mangiapia G, Vaccaro M, Gianolio E, Heenan RK, Paduano L, Morelli G
* Micelles obtained by aggregation of gemini surfactants containing the CCK8 peptide and a gadolinium complex (379 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257linking), 2009 May; 14(4): 587-599.
Impact Factor: 3.415
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Garzia L, Andolfo I, Cusanelli E, Marino N, Petrosino G, De Martino D, Esposito V, Galeone A, Navas L, Esposito S, Gargiulo S, Fattet S, Donofrio V, Cinalli G, Brunetti A, Del Vecchio L, Northcott PA, Delattre O, Taylor MD, Iolascon A, Zollo M
* MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma (415 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2009 Mar 24; 4(3): e4998-e4998.
Impact Factor: 4.351
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Morisco A, Accardo A, Gianolio E, Tesauro D, Benedetti E, Morelli G
* Micelles derivatized with octreotide as potential target-selective contrast agents in MRI (337 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 242-250.
Impact Factor: 1.807
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Sorriento D, Campanile A, Santulli G, Leggiero E, Pastore L, Trimarco B, Iaccarino G
* A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity (336 visite)
Mol Cancermolecular Cancer (ISSN: 1476-4598), 2009; 8: N/D-N/D.
Impact Factor: 4.16
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Mancini M, Speranza A, Greco A, Salvatore M
* Effects Of High Frequency Ultrasound On Echogenicity Of Ultrasound Contrast Agents Solutions (222 visite)
Endocrinology, 2009; 35(8S): 221-221.
Impact Factor: 4.503
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Tesauro D, Morelli G, Del Pozzo L, Pedone C, Tornesello AL, Benedetti E
* Supramolecular aggregates derivatized by CCK8 peptide as selective nanocarriers for drug delivery (339 visite)
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print), 2009; 611: 603-604.
Impact Factor: 2.02
Dettagli Esporta in BibTeX Esporta in EndNote
Vaccaro M, Mangiapia G, Accardo A, Tesauro D, Gianolio E, Frielinghaus H, Morelli G, Paduano L
* Polymerized mixed aggregates containing gadolinium complex and CCK8 peptide (339 visite)
Colloid Polym Sci (ISSN: 0303-402x), 2008 Dec; 286(14-15): 1643-1652.
Impact Factor: 1.736
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Tesauro D, Benedetti E, Pedone C, Morelli G
* Naposomes: A new class of peptide containing supramolecular aggregates as target selective delivery systems (226 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Tesauro D, Aloj L, Tarallo L, Arra C, Mangiapia G, Vaccaro M, Pedone C, Paduano L, Morelli G
* Peptide-containing aggregates as selective nanocarriers for therapeutics (348 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2008 Apr; 3(4): 594-602.
Impact Factor: 3.15
Dettagli Esporta in BibTeX Esporta in EndNote
Breveglieri G, Pensato S, Salvatori F, Saviano M, Pedone C, Romanelli A, Gambari R
* PNA-mediated alteration of mRNA splicing (309 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 175-181.
Impact Factor: 0.1
Dettagli Esporta in BibTeX Esporta in EndNote
Vaccaro M, Mangiapia G, Paduano L, Gianolio E, Accardo A, Tesauro D, Morelli G
* Structural and relaxometric characterization of peptide aggregates containing gadolinium complexes as potential selective contrast agents in MRI (535 visite)
Chemphyschem (ISSN: 1439-4235, 1439-7641, 1439-7641electronic), 2007 Dec 3; 8(17): 2526-2538.
Impact Factor: 3.502
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Vaccaro M, Accardo A, D'Errico G, Schillen K, Radulescu A, Tesauro D, Morelli G, Paduano L
* Peptides and gd complexes containing colloidal assemblies as tumor-specific contrast agents in MRI: Physicochemical characterization (374 visite)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2007 Sep; 93(5): 1736-1746.
Impact Factor: 4.627
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Tesauro D, Accardo A, Gianolio E, Paduano L, Teixeira J, Schillén K, Aime S, Morelli G
* Peptide derivatized lamellar aggregates as target-specific MRI contrast agents (418 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 25; 8(8): 950-955.
Impact Factor: 3.446
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Accardo A, Tesauro D, Morelli G, Gianolio E, Aime S, Vaccaro M, Mangiapia G, Paduano L, Schillén K
* High-relaxivity supramolecular aggregates containing peptides and Gd complexes as contrast agents in MRI (383 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2007 Feb; 12(2): 267-276.
Impact Factor: 3.325
Dettagli Esporta in BibTeX Esporta in EndNote
Mainenti PP, Cirillo LC, Camera L, Persico F, Cantalupo T, Pace L, De Palma GD, Persico G, Salvatore M
* Accuracy of single phase contrast enhanced multidetector CT colonography in the preoperative staging of colo-rectal cancer (297 visite)
Eur J Radiol (ISSN: 0720-048x), 2006 Dec; 60(3): 453-459.
Impact Factor: 1.332
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Vaccaro M, Accardo A, Tesauro D, Mangiapia G, Loef D, Schillen K, Soederman O, Morelli G, Paduan L
* Supramolecular aggregates of amphiphilic gadolinium complexes as blood pool MRI/MRA contrast agents: Physicochemical characterization (367 visite)
Langmuir (ISSN: 0743-7463), 2006 Jul 18; 22(15): 6635-6643.
Impact Factor: 3.902
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Cittadini A, Monti MG, Iaccarino G, Di Rella F, Tsichlis PN, Di Gianni A, Strömer H, Sorriento D, Peschle C, Trimarco B, Saccà L, Condorelli G
* Adenoviral gene transfer of Akt enhances myocardial contractility and intracellular calcium handling (518 visite)
Gene Ther (ISSN: 0969-7128, 0969-7128linking), 2006; 13(1): 8-19.
Impact Factor: 4.782
Dettagli Esporta in BibTeX Esporta in EndNote
Morelli G, Accardo A, Tesauro D, Pedone C, Mangiapia G, Paduano L, Gianolio E
* Multicomponent aggregates containing the CCK8 bioactive peptide and Gd complexes as target-specific MRI contrast agents (230 visite)
Peptides 2004 Proceedings, 2005; N/D: N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Tesauro D, Roscigno P, Gianolio E, Paduano L, D'Errico G, Pedone C, Morelli G
* Physicochemical Properties of Mixed Micellar Aggregates Containing CCK Peptides and Gd Complexes Designed as Tumor Specific Contrast Agents in MRI (421 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2004 Mar 17; 126(10): 3097-3107.
Impact Factor: 6.903
Dettagli Esporta in BibTeX Esporta in EndNote
Mangiapia G, Accardo A, Celso FL, Tesauro D, Morelli G, Radulescu A, Paduano L
* Mixed micelles composed of peptides and gadolinium complexes as tumor-specific contrast agents in MRI: A sans study (554 visite)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2004; 108(45): 17611-17617.
Impact Factor: 3.834
Dettagli Esporta in BibTeX Esporta in EndNote
Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R
* Cationic Liposomes As Delivery Systems For Double-Stranded Pna-Dna Chimeras Exhibiting Decoy Activity Against Nf-Kappab Transcription Factors (371 visite)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2002 Sep 15; 64(4): 609-616.
Impact Factor: 3.542
Dettagli Esporta in BibTeX Esporta in EndNote
69 Records (64 escludendo Abstract e Conferenze).
Impact factor totale: 252.843 (239.352 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 275.863 (261.704 escludendo Abstract e Conferenze).
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