Maldi, Ap/Maldi And Esi Techniques For The Ms Detection Of Amyloid Beta-Peptides
CNR Ibb | back to homepage
▲NavBar
Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]


Maldi, Ap/Maldi And Esi Techniques For The Ms Detection Of Amyloid Beta-Peptides (188 visite)

Grasso G, Mineo P, Rizzarelli E, Spoto G

Int J Mass Spectrom (ISSN: 1387-3806), 2009 Apr 15; 282(1-2): 50-55.



Tipo di articolo: Journal Article,

Impact factor: 2.117, Impact factor a 5 anni: 2.304

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-62849088434&partnerID=40&md5=09bac6b3b2d72966923887abe0884156

Parole chiave: Amyloid Peptide, Fragmentation, Maldi, Matrix,

Affiliazioni:

*** IBB - CNR ***
Chemistry Department, Università di Catania, Viale Andrea Doria 6, 95125 Catania, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, Catania, Italy


Riferimenti:

Butterfield, D.A., Reed, T., Newman, S.F., Sultana, R., (2007) Free Radic. Biol. Med., 43, p. 65

Selkoe, D.J., (1994) J. Neuropathol. Exp. Neurol., 53, p. 438

Hamley, I.W., (2007) Angew. Chem. Int. Ed., 46, p. 8128

Nilsson, K.P., Hammarstroem, P., Ahlgren, F., Herland, A., Schnell, E.A., Lindgren, M., Westermark, G.T., Inganaes, O., (2006) ChemBioChem, 7, p. 1096

Arbustivi, E., Morbini, P., Verga, L., Concardi, M., Porcu, E., Pilotto, A., Zorzoli, I., Merlini, G., (1997) Amyloid, 4, p. 157

Cleary, J., Walsh, D.M., Hofmeister, J.J., Shankar, G.M., Kuskowski, M.A., Selkoe, D.J., Ashe, K.H., (2005) Nat. Neurosci., 8, p. 79

Lambert, M.P., Barlow, A.K., Chromy, B.A., Edwards, C., Freed, R., Liosatos, M., Morgan, T.E., Klein, W.L., (1998) Proc. Natl. Acad. Sci., 95, p. 6448

Kanemitsu, H., Tomiyama, T., Mori, H., (2003) Neurosci. Lett., 350, p. 113

Turner, A.J., Fisk, L., Nalivaeva, N.N., (2004) Ann. N.Y. Acad. Sci., 1035, p. 1

Eckman, E.A., Eckman, C.B., (2005) Biochem. Soc. Trans., 33, p. 1101

Luchsinger, J.A., Tang, M.X., Shea, S., Mayeux, R., (2004) Neurology, 63, p. 1187

Qiu, W.Q., Folstein, M.F., (2006) Neurobiol. Aging, 27, p. 190

Kurochkin, I.V., Goto, S., (1994) FEBS Lett., 345, p. 33

Mukherjee, A., Song, E., Kihiko-Ehmann, M., Goodman Jr., J.P., Pyrek, J.S., Estus, S., Hersh, L.B., (2000) J. Neurosci., 20, p. 8745

Leissring, M.A., Lu, A., Condron, M.M., Teplow, D.B., Stein, R.L., Farris, W., Selkoe, D.J., (2003) J. Biol. Chem., 278, p. 37314

Morelli, L., Llovera, R., Gonzalez, S.A., Affranchino, J.L., Prelli, F., Frangine, B., Ghiso, J., Castaño, E.M., (2003) J. Biol. Chem., 278, p. 23221

Chesneau, V., Vekrellis, K., Rosner, M.R., Selkoe, D.J., (2000) Biochem. J., 351, p. 509

Grasso, G., Rizzarelli, E., Spoto, G., (2007) J. Mass Spectrom., 42, p. 1590

Calero, M., Gasset, M., (2005) Methods Mol. Biol., 299, p. 129

Hosia, W., Griffiths, W.J., Johansson, J., (2005) J. Mass Spectrom., 40, p. 142

Trimpin, S., Deinzer, M.L., (2007) J. Am. Soc. Mass Spectrom., 18, p. 1533

Shen, C.-L., Murphy, R.M., (1995) Biophys. J., 69, p. 640

Chen, M., Cook, K.D., (2007) Anal. Chem., 79, p. 2031

Klug, G.M.J.A., Losic, D., Subasinghe, S.S., Aguilar, M.-I., Martin, L.L., Small, D.H., (2003) Eur. J. Biochem., 270, p. 4282

Taylor, B.M., Sarver, R.W., Fici, G., Poorman, R.A., Lutzke, B.S., Molinari, A., Kawabe, T., Epps, D.E., (2003) J. Protein Chem., 22, p. 31

Snyder, S.W., Ladror, U.S., Wade, W.S., Wang, G.T., Barrett, L.W., Matayoshi, E.D., Huffaker, H.J., Holzman, T.F., (1994) Biophys. J., 67, p. 1216

Sabaté, R., Gallardo, M., Estelrich, J., (2005) Int. J. Biol. Macromol., 35, p. 9

Tan, P.V., Laiko, V.V., Doroshenko, V.M., (2004) Anal. Chem., 75, p. 2462

Kheterpal, I., Cook, K.D., Wetzel, R., (2006) Methods Enzymol., 413, p. 140

Kheterpal, I., Chen, M., Cook, K., Wetzel, R., (2006) J. Mol. Biol., 361, p. 785

Smith, A.M., Jahn, T.R., Ashcroft, A.E., Radford, S.E., (2006) J. Mol. Biol., 364, p. 9

Caddy, G.L., Robinson, C.V., (2006) Protein Peptide Lett., 13, p. 255

Mehl, J.T., Cummings, J.J., Rohde, E., Yates, N.N., (2003) Rapid Commun. Mass Spectrom., 17, p. 1600

Grasso, G., Fragai, M., Rizzarelli, E., Spoto, G., Kwon, J.Y., (2006) J. Mass Spectrom., 41, p. 1561

Mayrhofer, C., Krieger, S., Raptakis, E., Allmaier, G., (2006) J. Proteome Res., 5, p. 1967

Konn, D.O., Murrell, J., Despeyroux, D., Gaskell, S.J., (2005) J. Am. Soc. Mass Spectrom., 16, p. 743

Cohen, S.L., Chait, B.T., (1996) Anal. Chem., 68, p. 31

Nikogosyan, D.N., Görner, H., (1999) IEEE J. Sel. Top. Quant. Electronics, 5, p. 1107

Karas, M., Hillenkamp, F., (1988) Anal. Chem., 60, p. 2299

Brown, R.S., Feng, J., Reiber, D.C., (1997) Int. J. Ion Process. Mass Spectrom., 169-170, p. 1

Petre, B.-A., Youhnovski, N., Lukkari, J., Weber, R., Przybylski, M., (2005) Eur. J. Mass Spectrom., 11, p. 513

Sadagopan, N., Watson, J.T., (2000) J. Am. Soc. Mass Spectrom., 11, p. 107

Wang, D.-S., Dickson, D.W., Malter, J.S., (2006) J. Biomed. Biotechnol. ID, 58406, p. 1

Song, E.-S., Mukherjee, A., Juliano, M.A., St Pyrek, J., Goodman, J.P., Juliano Jr., L., Hersh, L.B., (2001) J. Biol. Chem., 276, p. 1152

Zagorski, M.G., Yang, J., Shao, H., Ma, K., Zeng, H., Hong, A., (1999) Methods Enzymol., 309, p. 189

Misiti, F., Sampaolese, B., Pezzotti, M., Marini, S., Coletta, M., Ceccarelli, L., Giardina, B., Clementi, M.E., (2005) Neurochem. Int., 46, p. 575

Grasso, G., D'Agata, R., Rizzarelli, E., Spoto, G., D'Andrea, L., Pedone, C., Picardi, A., Yeo, K.J., (2005) J. Mass Spectrom., 40, p. 1565

Butterfield, D. A., Reed, T., Newman, S. F., Sultana, R., (2007) Free Radic. Biol. Med., 43, p. 65

Selkoe, D. J., (1994) J. Neuropathol. Exp. Neurol., 53, p. 438

Hamley, I. W., (2007) Angew. Chem. Int. Ed., 46, p. 8128

Nilsson, K. P., Hammarstroem, P., Ahlgren, F., Herland, A., Schnell, E. A., Lindgren, M., Westermark, G. T., Inganaes, O., (2006) ChemBioChem, 7, p. 1096

Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Klein, W. L., (1998) Proc. Natl. Acad. Sci., 95, p. 6448

Turner, A. J., Fisk, L., Nalivaeva, N. N., (2004) Ann. N. Y. Acad. Sci., 1035, p. 1

Eckman, E. A., Eckman, C. B., (2005) Biochem. Soc. Trans., 33, p. 1101

Luchsinger, J. A., Tang, M. X., Shea, S., Mayeux, R., (2004) Neurology, 63, p. 1187

Qiu, W. Q., Folstein, M. F., (2006) Neurobiol. Aging, 27, p. 190

Kurochkin, I. V., Goto, S., (1994) FEBS Lett., 345, p. 33

Leissring, M. A., Lu, A., Condron, M. M., Teplow, D. B., Stein, R. L., Farris, W., Selkoe, D. J., (2003) J. Biol. Chem., 278, p. 37314

Shen, C. -L., Murphy, R. M., (1995) Biophys. J., 69, p. 640

Chen, M., Cook, K. D., (2007) Anal. Chem., 79, p. 2031

Klug, G. M. J. A., Losic, D., Subasinghe, S. S., Aguilar, M. -I., Martin, L. L., Small, D. H., (2003) Eur. J. Biochem., 270, p. 4282

Taylor, B. M., Sarver, R. W., Fici, G., Poorman, R. A., Lutzke, B. S., Molinari, A., Kawabe, T., Epps, D. E., (2003) J. Protein Chem., 22, p. 31

Snyder, S. W., Ladror, U. S., Wade, W. S., Wang, G. T., Barrett, L. W., Matayoshi, E. D., Huffaker, H. J., Holzman, T. F., (1994) Biophys. J., 67, p. 1216

Sabat, R., Gallardo, M., Estelrich, J., (2005) Int. J. Biol. Macromol., 35, p. 9

Tan, P. V., Laiko, V. V., Doroshenko, V. M., (2004) Anal. Chem., 75, p. 2462

Smith, A. M., Jahn, T. R., Ashcroft, A. E., Radford, S. E., (2006) J. Mol. Biol., 364, p. 9

Caddy, G. L., Robinson, C. V., (2006) Protein Peptide Lett., 13, p. 255

Mehl, J. T., Cummings, J. J., Rohde, E., Yates, N. N., (2003) Rapid Commun. Mass Spectrom., 17, p. 1600

Konn, D. O., Murrell, J., Despeyroux, D., Gaskell, S. J., (2005) J. Am. Soc. Mass Spectrom., 16, p. 743

Cohen, S. L., Chait, B. T., (1996) Anal. Chem., 68, p. 31

Nikogosyan, D. N., G rner, H., (1999) IEEE J. Sel. Top. Quant. Electronics, 5, p. 1107

Brown, R. S., Feng, J., Reiber, D. C., (1997) Int. J. Ion Process. Mass Spectrom., 169-170, p. 1

Petre, B. -A., Youhnovski, N., Lukkari, J., Weber, R., Przybylski, M., (2005) Eur. J. Mass Spectrom., 11, p. 513

Wang, D. -S., Dickson, D. W., Malter, J. S., (2006) J. Biomed. Biotechnol. ID, 58406, p. 1

Song, E. -S., Mukherjee, A., Juliano, M. A., St Pyrek, J., Goodman, J. P., Juliano Jr., L., Hersh, L. B., (2001) J. Biol. Chem., 276, p. 1152

Zagorski, M. G., Yang, J., Shao, H., Ma, K., Zeng, H., Hong, A., (1999) Methods Enzymol., 309, p. 189



Amyloid β-peptides (Aβs) are involved in several neuropathological conditions such as Alzheimer's disease and considerable experimental evidences have emerged indicating that different proteases play a major role in regulating the accumulation of Aβs in the brain. Particularly, insulin-degrading enzyme (IDE) has been shown to degrade Aβs at different cleavage sites, but the experimental results reported in the literature and obtained by mass spectrometry methods are somehow fragmentary. The detection of Aβs is often complicated by solubility issues, oxidation artifacts and spontaneous aggregation/cleavage and, in order to rationalize the different reported results, we analyzed Aβs solutions by three different MS approaches: matrix assisted laser desorption ionization-time of flight (MALDI-TOF), atmospheric pressure (AP) MALDI ion trap and electrospray ionization (ESI) ion trap. Differences in the obtained results are discussed and ESI is chosen as the most suitable MS method for Aβs detection. Finally, cleavage sites produced by interaction of Aβs with IDE are identified, two of which had never been reported in the literature. © 2009 Elsevier B.V. All rights reserved.
Nessun risultato.
Nessun risultato.

Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]
Vai a fine pagina   Versione per copia e incolla facile   Esporta tutto in BibTeX   Esporta tutto in EndNote


Palladino P, Aura AM, Spoto G
* Surface plasmon resonance for the label-free detection of Alzheimer's β-amyloid peptide aggregation (199 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2016; 408(3): 849-854.
Impact Factor: 3.431
Dettagli    Esporta in BibTeX    Esporta in EndNote

Giuffrida M, Caraci F, Tomasello F, Pappalardo G, Rizzarelli E, Nicoletti F, Copani AG
* Shared and distinct features of beta-amyloid peptides (167 visite)
Society For Neuroscience Abstract Viewer And Itinerary Planner, 2013; 43: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (118 visite)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M
* Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity (176 visite)
J Mol Biol (ISSN: 1089-8638, 0022-2836, 1089-8638electronic), 2009 Feb 6; 385(5): 1556-1567.
Impact Factor: 3.871
Dettagli    Esporta in BibTeX    Esporta in EndNote

Gioia M, Monaco S, Van Den Steen PE, Sbardella D, Grasso G, Marini S, Overall CM, Opdenakker G, Coletta M
* The Collagen Binding Domain of Gelatinase A Modulates Degradation of Collagen IV by Gelatinase (117 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009; 386(2): 419-434.
Impact Factor: 3.871
Dettagli    Esporta in BibTeX    Esporta in EndNote

Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (155 visite)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
Dettagli    Esporta in BibTeX    Esporta in EndNote

Wiesehan K, Buder K, Linke RP, Patt S, Stoldt M, Unger E, Schmitt B, Bucci E, Willbold D
* Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide Aβ1-42 by mirror image phage display (185 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003; 4(8): 748-753.
Impact Factor: 3.992
Dettagli    Esporta in BibTeX    Esporta in EndNote

Russo M, Palumbo R, Tedesco I, Mazzarella G, Russo P, Iacomino G, Russo GL
Quercetin and anti-CD95(Fas/Apo1) enhance apoptosis in HPB-ALL cell line (104 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 1999 Dec 3; 462(3): 322-328.
Impact Factor: 3.72
Dettagli    Esporta in BibTeX    Esporta in EndNote



8 Records (7 escludendo Abstract e Conferenze).
Impact factor totale: 28.037 (28.037 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 22.632 (22.632 escludendo Abstract e Conferenze).







    Esporta in BibTeX    Esporta in EndNote