Home Ricerca Sedi Chi siamo Organigramma Personale Contatti Didattica Login Documenti EN
Progetti in evidenza
INCIPIT
(Link esterno)

ISTAPCA
(1206 visite)

Fondo Europeo Pesca
(618 visite)

Euro-BioImaging
(Link esterno)

Fondazione Veronesi
(Link esterno)

LightDyNAmics
(1089 visite)

 INMiND
(1183 visite)

Instruct-IT
(Link esterno)

 PRIN
(1326 visite)

 eHealthNet
(1087 visite)

Ponrec
(1026 visite)

MFAG Grant
(1131 visite)

MERIT
(Link esterno)


Collegamenti

Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]
Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]



Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis (94 visite)

Esposito C, Pethoukov MV, Svergun DI, Ruggiero A, Pedone C, Pedone E, Berisio R

J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530), 2008 Jul; 190(13): 4749-4753.

Tipo di articolo: Journal Article, Research Support, Non-U. S. Gov'T, , Impact factor: 3.636, Impact factor a 5 anni: 3.748, Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-46049101224&partnerID=40&md5=ffa991593ccfb2b9579bb3bdd5452fc1

Parole chiave: Hemagglutinin, Heparin Binding Protein, Article, Bacterial Virulence, Chemical Analysis, Mycobacterium Tuberculosis, Nonhuman, Priority Journal, Radiation Scattering, Structure Analysis, Bacterial Proteins, Circular Dichroism, Dimerization, Lectins, Models, Molecular, Synchrotrons, X-Rays,

Affiliazioni: *** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, C.N.R., I-80134, Napoli, Italy
European Molecular Biology Lab., Hamburg, c/o DESY, Notkestrasse 85, 22603 Hamburg, Germany
Dipartimento Delle Scienze Biologiche, Sezione di Biostrutture, Università degli Studi di Napoli Federico II, I-80134, Napoli, Italy


Riferimenti: Alfadhli, A., Steel, E., Finlay, L., Bachinger, H.P., Barklis, E., Hantavirus nucleocapsid protein coiled-coil domains (2002) J. Biol. Chem, 277, pp. 27103-2710

Alteri, C.J., Xicohtencatl-Cortes, J., Hess, S., Caballero-Olin, G., Giron, J.A., Friedman, R.L., Mycobacterium tuberculosis produces pili during human infection (2007) Proc. Natl. Acad. Sci. USA, 104, pp. 5145-5150

Berger, P., Schaffitzel, C., Berger, I., Ban, N., Suter, U., Membrane association of myotubularin-related protein 2 is mediated by a pleckstrin homology-GRAM domain and a coiled-coil dimerization module (2003) Proc. Natl. Acad. Sci. USA, 100, pp. 12177-12182

Delogu, G., Brennan, M.J., Functional domains present in the mycobacterial hemagglutinin, HBHA (1999) J. Bacteriol, 181, pp. 7464-7469

Gruber, M., Soding, J., Lupas, A.N., Comparative analysis of coiled-coil prediction methods (2006) J. Struct. Biol, 155, pp. 140-145

Hougardy, J. M., K. Schepers, S. Place, A. Drowart, V. Lechevin, V. Vers cheure, A. S. Debrie, T. M. Doherty, J. P. Van Vooren, C. Locht, and F. Mascart. 2007. Heparin-binding-hemagglutinin-induced IFN-gamma release as a diagnostic tool for latent tuberculosis. PLoS One 2:e926Jelesarov, I., Bosshard, H.R., Thermodynamic characterization of the coupled folding and association of heterodimeric coiled coils (leucine zippers) (1996) J. Mol. Biol, 263, pp. 344-358

Kammerer, R.A., Steinmetz, M.O., De novo design of a two-stranded coiled-coil switch peptide (2006) J. Struct. Biol, 155, pp. 146-153

Konarev, P.V., Petoukhov, M.V., Volkov, V.V., Svergun, D.I., ATSAS 2.1, a program package for small-angle scattering data analysis (2006) J. Appl. Crystallogr, 39, pp. 277-286

Konarev, P.V., Volkov, V.V., Sokolova, A.V., Koch, M.H.J., Svergun, D.I., PRIMUS - a Windows-PC based system for small-angle scattering data analysis (2003) J. Appl. Crystallogr, 36, pp. 277-1282

Kozin, M.B., Svergun, D.I., Automated matching of high- and low-resolution structural models (2001) J. Appl. Crystallogr, 34, pp. 33-41

Liu, J., Zheng, Q., Deng, Y., Cheng, C.S., Kallenbach, N.R., Lu, M., A seven-helix coiled coil (2006) Proc. Natl. Acad. Sci. USA, 103, pp. 15457-15462

Locht, C., Hougardy, J.M., Rouanet, C., Place, S., Mascart, F., Heparin-binding hemagglutinin, from an extrapulmonary dissemination factor to a powerful diagnostic and protective antigen against tuberculosis (2006) Tuberculosis (Edinburgh), 86, pp. 303-309

Menozzi, F.D., Bischoff, R., Fort, E., Brennan, M.J., Locht, C., Molecular characterization of the mycobacterial heparin-binding hemagglutinin, a mycobacterial adhesin (1998) Proc. Natl. Acad. Sci. USA, 95, pp. 12625-12630

Menozzi, F.D., Reddy, V.M., Cayet, D., Raze, D., Debrie, A.S., Dehouck, M.P., Cecchelli, R., Locht, C., Mycobacterium tuberculosis heparin-binding haemagglutinin adhesin (HBHA) triggers receptor-mediated transcytosis without altering the integrity of tight junctions (2006) Microbes Infect, 8, pp. 1-9

Menozzi, F.D., Rouse, J.H., Alavi, M., Laude-Sharp, M., Muller, J., Bischoff, R., Brennan, M.J., Locht, C., Identification of a heparin-binding hemagglutinin present in mycobacteria (1996) J. Exp. Med, 184, pp. 993-1001

Parra, M., Pickett, T., Delogu, G., Dheenadhayalan, V., Debrie, A.S., Locht, C., Brennan, M.J., The mycobacterial heparin-binding hemagglutinin is a protective antigen in the mouse aerosol challenge model of tuberculosis (2004) Infect. Immun, 72, pp. 6799-6805

Pethe, K., Alonso, S., Biet, F., Delogu, G., Brennan, M.J., Locht, C., Menozzi, F.D., The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination (2001) Nature, 412, pp. 190-194

Pethe, K., Aumercier, M., Fort, E., Gatot, C., Locht, C., Menozzi, F.D., Characterization of the heparin-binding site of the mycobacterial heparin-binding hemagglutinin adhesin (2000) J. Biol. Chem, 275, pp. 14273-14280

Pethe, K., Bifani, P., Drobecq, H., Sergheraert, C., Debrie, A.S., Locht, C., Menozzi, F.D., Mycobacterial heparin-binding hemagglutinin and laminin-binding protein share antigenic methyllysines that confer resistance to proteolysis (2002) Proc. Natl. Acad. Sci. USA, 99, pp. 10759-10764

Petoukhov, M.V., Svergun, D.I., Joint use of small-angle X-ray and neutron scattering to study biological macromolecules in solution (2006) Eur. Biophys. J, 35, pp. 567-576

Porod, G., General theory (1982) Small-angle X-ray scattering, pp. 17-51. , O. Kratky ed, Academic Press, London, United Kingdom

Remaut, H., Rose, R.J., Hannan, T.J., Hultgren, S.J., Radford, S.E., Ashcroft, A.E., VVaksman, G., Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism (2006) Mol. Cell, 22, pp. 831-842

Roessle, M.W., Klaering, R., Ristau, U., Robrahn, B., Jahn, D., Gehrmann, T., Konarev, P., Svergun, D., Upgrade of the small-angle X-ray scattering beamline X33 at the European Molecular Biology Laboratory, Hamburg (2007) J. Appl. Crystallogr, 40, pp. s190-s194

Steinmetz, M.O., Jelesarov, I., Matousek, W.M., Honnappa, S., Jahnke, W., Missimer, J.H., Frank, S., Kammerer, R.A., Molecular basis of coiled-coil formation (2007) Proc. Natl. Acad. Sci. USA, 104, pp. 7062-7067

Svergun, D.I., Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing (1999) Biophys. J, 76, pp. 2879-2886

Svergun, D.I., Petoukhov, M.V., Koch, M.H.J., Determination of domain structure of proteins from X-ray solution scattering (2001) Biophys. J, 80, pp. 2946-2953

Verbelen, C., Dupres, V., Raze, D., Dewitte, F., Locht, C., Dufrene, Y.F., Single-molecule force spectroscopy of mycobacterial adhesin-adhesin interactions (2007) J. Bacteriol, 189, pp. 8801-8806

Vitagliano, L., Ruggiero, A., Pedone, C., Berisio, R., A molecular dynamics study of pilus subunits: Insights into pilus biogenesis (2007) J. Mol. Biol, 367, pp. 935-941

Wilson, I.A., Skehel, J.J., Wiley, D.C., Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution (1981) Nature, 289, pp. 366-373

Wolf, E., Kim, P.S., Berger, B., MultiCoil: A program for predicting two- and three-stranded coiled coils (1997) Protein Sci, 6, pp. 1179-1189

Alteri, C. J., Xicohtencatl-Cortes, J., Hess, S., Caballero-Olin, G., Giron, J. A., Friedman, R. L., Mycobacterium tuberculosis produces pili during human infection (2007) Proc. Natl. Acad. Sci. USA, 104, pp. 5145-5150

Kammerer, R. A., Steinmetz, M. O., De novo design of a two-stranded coiled-coil switch peptide (2006) J. Struct. Biol, 155, pp. 146-153

Konarev, P. V., Petoukhov, M. V., Volkov, V. V., Svergun, D. I., ATSAS 2. 1, a program package for small-angle scattering data analysis (2006) J. Appl. Crystallogr, 39, pp. 277-286

Konarev, P. V., Volkov, V. V., Sokolova, A. V., Koch, M. H. J., Svergun, D. I., PRIMUS - a Windows-PC based system for small-angle scattering data analysis (2003) J. Appl. Crystallogr, 36, pp. 277-1282

Kozin, M. B., Svergun, D. I., Automated matching of high- and low-resolution structural models (2001) J. Appl. Crystallogr, 34, pp. 33-41

Menozzi, F. D., Bischoff, R., Fort, E., Brennan, M. J., Locht, C., Molecular characterization of the mycobacterial heparin-binding hemagglutinin, a mycobacterial adhesin (1998) Proc. Natl. Acad. Sci. USA, 95, pp. 12625-12630

Menozzi, F. D., Reddy, V. M., Cayet, D., Raze, D., Debrie, A. S., Dehouck, M. P., Cecchelli, R., Locht, C., Mycobacterium tuberculosis heparin-binding haemagglutinin adhesin (HBHA) triggers receptor-mediated transcytosis without altering the integrity of tight junctions (2006) Microbes Infect, 8, pp. 1-9

Menozzi, F. D., Rouse, J. H., Alavi, M., Laude-Sharp, M., Muller, J., Bischoff, R., Brennan, M. J., Locht, C., Identification of a heparin-binding hemagglutinin present in mycobacteria (1996) J. Exp. Med, 184, pp. 993-1001

Petoukhov, M. V., Svergun, D. I., Joint use of small-angle X-ray and neutron scattering to study biological macromolecules in solution (2006) Eur. Biophys. J, 35, pp. 567-576

Roessle, M. W., Klaering, R., Ristau, U., Robrahn, B., Jahn, D., Gehrmann, T., Konarev, P., Svergun, D., Upgrade of the small-angle X-ray scattering beamline X33 at the European Molecular Biology Laboratory, Hamburg (2007) J. Appl. Crystallogr, 40, pp. s190-s194

Steinmetz, M. O., Jelesarov, I., Matousek, W. M., Honnappa, S., Jahnke, W., Missimer, J. H., Frank, S., Kammerer, R. A., Molecular basis of coiled-coil formation (2007) Proc. Natl. Acad. Sci. USA, 104, pp. 7062-7067

Svergun, D. I., Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing (1999) Biophys. J, 76, pp. 2879-2886

Svergun, D. I., Petoukhov, M. V., Koch, M. H. J., Determination of domain structure of proteins from X-ray solution scattering (2001) Biophys. J, 80, pp. 2946-2953

Wilson, I. A., Skehel, J. J., Wiley, D. C., Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution (1981) Nature, 289, pp. 366-373

Wolf, E., Kim, P. S., Berger, B., MultiCoil: A program for predicting two- and three-stranded coiled coils (1997) Protein Sci, 6, pp. 1179-1189



Heparin-binding hemagglutinin (HBHA) is a virulence factor of tuberculosis which is responsible for extrapulmonary dissemination of this disease. A thorough biochemical characterization of HBHA has provided experimental evidence of a coiled-coil nature of HBHA. These data, together with the low-resolution structures of a full-length form and a truncated form of HBHA obtained by small-angle X-ray scattering, have unambiguously indicated that HBHA has a dimeric structure with an elongated shape. Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]
Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]


Squeglia F, Ruggiero A, Berisio R
* Chemistry of Peptidoglycan in Mycobacterium tuberculosis life style: an off-the-wall balance of synthesis and degradation (150 visite) (PDF 115 visite)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018; 24: 2533-2546.
Impact Factor: 5.317
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ruggiero A, Squeglia F, RomanoM, Vitagliano L, De Simone A, Berisio R
* Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis (99 visite)
J Biomol Struct Dyn (ISSN: 1538-0254electronic, 0739-1102linking), 2017 May; 35(6): 1322-1330.
Impact Factor: 3.123
Dettagli    Esporta in BibTeX    Esporta in EndNote

Romanò MF, Squeglia F, Berisio R
* Structure and Function of RNase AS, a Novel Virulence Factor from Mycobacterium Tuberculosis (115 visite)
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2015 Apr 17; 22(14): 1745-1756.
Impact Factor: 3.455
Dettagli    Esporta in BibTeX    Esporta in EndNote

Squeglia F, Ruggiero A, Romanò MF, Vitagliano L, Berisio R
* Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: Evidence for the l-to-d inversion of configuration of the catalytic cysteine (128 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2014 Sep; 70(9): 2295-2300.
Impact Factor: 14.1
Dettagli    Esporta in BibTeX    Esporta in EndNote

Calvanese L, Falcigno L, Maglione C, Marasco D, Ruggiero A, Squeglia F, Berisio R, D'Auria G
* Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis (131 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Jul; 101(7): 712-719.
Impact Factor: 2.385
Dettagli    Esporta in BibTeX    Esporta in EndNote

Romanò MF, Van De Weerd R, Brouwer FCC, Roviello GN, Lacroix R, Sparrius M, Van Den Brink-van Stempvoort G, Maaskant JJ, Van Der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R
* Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo (125 visite)
Structurestructure (ISSN: 0969-2126, 1878-4186), 2014 May 6; 22(5): 719-730.
Impact Factor: 5.618
Dettagli    Esporta in BibTeX    Esporta in EndNote

Correale S, Ruggiero A, Capparelli R, Pedone E, Berisio R
* Structures of free and inhibited forms of the L, D-transpeptidase LdtMt1 from Mycobacterium tuberculosis (118 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Sep; 69(Pt9): 1697-1706.
Impact Factor: 7.232
Dettagli    Esporta in BibTeX    Esporta in EndNote

Squeglia F, Romanò MF, Ruggiero A, Vitagliano L, De Simone A, Berisio R
* Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses (119 visite)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jun 4; 104(11): 2530-2539.
Impact Factor: 3.832
Dettagli    Esporta in BibTeX    Esporta in EndNote

Correale S, Ruggiero A, Pedone E, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the l, d-transpeptidase LdtMt1 from Mycobacterium tuberculosis (131 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Mar 1; 69(3): 253-256.
Impact Factor: 0.568
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ruggiero A, Marchant J, Squeglia F, Makarov V, De Simone A, Berisio R
* Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis (96 visite)
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic), 2013 Feb 1; 31(2): 195-205.
Impact Factor: 2.983
Dettagli    Esporta in BibTeX    Esporta in EndNote

Esposito C, Cantisani M, D'Auria G, Falcigno L, Pedone E, Galdiero S, Berisio R
* Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination (118 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2012 Mar 23; 586(6): 659-667.
Impact Factor: 3.582
Dettagli    Esporta in BibTeX    Esporta in EndNote

Esposito C, Marasco D, Delogu G, Pedone E, Berisio R
* Heparin-binding hemagglutinin HBHA from Mycobacterium tuberculosis affects actin polymerisation (89 visite)
Biochem Biophys Res Commun (ISSN: 0006-291x), 2011 Jul 1; 410(2): 339-344.
Impact Factor: 2.484
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (109 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Auria G, Esposito C, Falcigno L, Calvanese L, Iaccarino E, Ruggiero A, Pedone C, Pedone E, Berisio R
* Dynamical properties of cold shock protein A from Mycobacterium tuberculosis (106 visite)
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic), 2010 Nov 26; 402(4): 693-698.
Impact Factor: 2.595
Dettagli    Esporta in BibTeX    Esporta in EndNote

Esposito C, Carullo C, Pedone E, Graziano G, Del Vecchio P, Berisio R
* Dimerisation and structural integrity of Heparin Binding Hemagglutinin A from Mycobacterium tuberculosis: Implications for bacterial agglutination (121 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 0014-5793linking), 2010 Mar 19; 584(6): 1091-1096.
Impact Factor: 3.601
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (91 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
Impact Factor: 0.645
Dettagli    Esporta in BibTeX    Esporta in EndNote

Esposito L, Vitagliano L, Sica F, Sorrentino G, Zagari A, Mazzarella L
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: Hydration and sterochemical analysis (157 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Mar 31; 297(3): 713-732.
Impact Factor: 5.388
Dettagli    Esporta in BibTeX    Esporta in EndNote



17 Records (17 escludendo Abstract e Conferenze).
Impact factor totale: 67.414 (67.414 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 60.498 (60.498 escludendo Abstract e Conferenze).







    Esporta in BibTeX    Esporta in EndNote

Ultima modifica di Rita Berisio in data Monday 16 November 2015, 15:35:09
94 visite. Ultima visita in data Monday 10 December 2018, 2:11:15

Webmaster and developer: Marco Comerci
Per problemi e suggerimenti: adminibb.cnr.it
Ultimo aggiornamento: Monday 17 December 2018, 14:29:05