Peroxiredoxins as cellular guardians in Sulfolobus solfataricus - characterization of Bcp1, Bcp3 and Bcp4 (171 visite)
Febs Journal (ISSN: 1742-464x), 2008 May; 275(9): 2067-2077.
Tipo di articolo: Journal Article,
Impact factor: 3.139, Impact factor a 5 anni: 3.421
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-42449109092&partnerID=40&md5=052229611002e70c70b8a87a0d6f8af8
Parole chiave: Antioxidant, Archaea, Disulfide Oxidoreductase, Oxidative Stress, Thiol-Peroxidase, Bacterioferritin Comigratory Protein 1, Peroxiredoxin, Reduced Nicotinamide Adenine Dinucleotide Phosphate, Thioredoxin, Thioredoxin Reductase, Unclassified Drug, Aeropyrum, Amino Acid Sequence, Article, Bacterial Growth, Comparative Study, Controlled Study, Enzyme Activity, Escherichia Coli, Gene Amplification, Gene Expression, Genetic Transcription, In Vivo Study, Nonhuman, Northern Blotting, Priority Journal, Protein Analysis, Protein Purification, Sequence Analysis, Sulfolobus Solfataricus, Temperature Dependence, Thermostability, Bacterial Proteins, Cloning, Molecular, Cysteine, Escherichia Coli Proteins, Molecular Sequence Data, Molecular Weight, Nadph Oxidoreductases, Oxidation-Reduction, Plasmids, Protein Structure, Quaternary, Recombinant Proteins, Sequence Homology, Thioredoxin-Disulfide Reductase, Aeropyrum Pernix,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Biologia Strutturale e Funzionale, Complesso Universitario di Monte S. Angelo, Università di Napoli 'Federico II', Via Cinthia, 80126 Naples, Italy
Istituto di Biostrutture e Bioimmagini, CNR, Naples, Italy
Riferimenti:
Imaly, J.A., Pathways of oxidative damage (2003) Annu Rev Microbiol, 57, pp. 395-41
Rho, B.S., Hung, L.W., Holton, J.M., Vigil, D., Kim, S.I., Park, M.S., Terwilliger, T.C., Pedelacq, J.D., Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis (2006) J Mol Biol, 361, pp. 850-863
Jeon, S.J., Ishikawa, K., Characterization of novel hexadecameric thioredoxin peroxidase from Aeropyrum pernix K1 (2003) J Biol Chem, 278, pp. 24174-24180
Dietz, K.J., Jacob, S., Oelze, M.L., Laxa, M., Tognetti, V., De Miranda, S.M., Baier, M., Finkemeier, I., The function of peroxiredoxins in plant organelle redox metabolism (2006) J Exp Bot, 57, pp. 1697-1709
Wood, Z.A., Schroder, E., Robin, H.J., Poole, L.B., Structure, mechanism and regulation of peroxiredoxins (2003) Trends Biochem Sci, 28, pp. 32-40
Seaver, L.C., Imlay, J.A., Alkyl hydroperoxide reductase is the primary scavenger of endogenous hydrogen peroxide in Escherichia coli (2001) J Bacteriol, 183, pp. 7173-7181
Kashima, Y., Ishikawa, K., Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii (2003) J Biochem (Tokyo), 134, pp. 25-29
Kawakami, R., Sakuraba, H., Kamohara, S., Goda, S., Kawarabayasi, Y., Ohshima, T., Oxidative stress response in an anaerobic hyperthermophilic archaeon: Presence of a functional peroxiredoxin in Pyrococcus horikoshii (2004) J Biochem (Tokyo), 136, pp. 541-547
She, Q., Singh, R.K., Confalonieri, F., Zivanovic, Y., Allard, G., Awayez, M.J., Chan-Weiher, C.C., De Moors, A., The complete genome of the crenarchaeon Sulfolobus solfataricus P2 (2001) Proc Natl Acad Sci USA, 98, pp. 7835-7840
Ursby, T., Adinolfi, B.S., Al-Karadaghi, S., De Vendittis, E., Bocchini, V., Iron superoxide dismutase from the archaeon Sulfolobus solfataricus: Analysis of structure and thermostability (1999) J Mol Biol, 286, pp. 189-205
Limauro, D., Pedone, E., Pirone, L., Bartolucci, S., Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (2006) FEBS J, 273, pp. 721-731
De Vendittis, E., Ursby, T., Rullo, R., Gogliettino, M.A., Masullo, M., Bocchini, V., Phenylmethanesulfonyl fluoride inactivates an archaeal superoxide dismutase by chemical modification of a specific tyrosine residue. Cloning, sequencing and expression of the gene coding for Sulfolobus solfataricus superoxide dismutase (2001) Eur J Biochem, 268, pp. 1794-1801
Cannio, R., D'Angelo, A., Rossi, M., Bartolucci, S., A superoxide dismutase from the archaeon Sulfolobus solfataricus is an extracellular enzyme and prevents the deactivation by superoxide of cell-bound proteins (2000) Eur J Biochem, 267, pp. 235-243
Bini, E., Dikshit, V., Dirksen, K., Drozda, M., Blum, P., Stability of mRNA in the hyperthermophilic archaeon Sulfolobus solfataricus (2002) RNA, 8, pp. 1129-1136
Limauro, D., Fiorentino, G., Bartolucci, S., How Sulfolobus responds to enviromental stress (2004) Biochemistry and Molecular Biology in the Thermophilic Archaeon Sulfolobus Solfataricus, pp. 105-130. , In. Farina, B. Faraone Mennella, M.R., eds. pp. Research Signpost, Kerala, India
Pedone, E., D'Ambrosio, K., De Simone, G., Rossi, M., Pedone, C., Bartolucci, S., Insights on a new PDI-like family: Structural and functional analysis of a protein disulfide oxidoreductase from the bacterium Aquifex aeolicus (2006) J Mol Biol, 356, pp. 155-164
Pedone, E., Limauro, D., D'Alterio, R., Rossi, M., Bartolucci, S., Characterization of a multifunctional protein disulfide oxidoreductase from Sulfolobus solfataricus (2006) FEBS J, 273, pp. 5407-5420
Stork, T., Michel, K.P., Pistorius, E.K., Dietz, K.J., Bioinformatic analysis of the genomes of the cyanobacteria Synechocystis sp. PCC 6803 and Synechococcus elongatus PCC 7942 for the presence of peroxiredoxins and their transcript regulation under stress (2005) J Exp Bot, 56, pp. 3193-3206
Copley, S.D., Novak, W.R., Babbitt, P.C., Divergence of function in the thioredoxin fold suprafamily: Evidence for evolution of peroxiredoxins from a thioredoxin-like ancestor (2004) Biochemistry, 43, pp. 13981-13995
Hosoya-Matsuda, N., Motohashi, K., Yoshimura, H., Nozaki, A., Inoue, K., Ohmori, M., Hisabori, T., Anti-oxidative stress system in cyanobacteria. Significance of type II peroxiredoxin and the role of 1-Cys peroxiredoxin in Synechocystis sp. strain PCC 6803 (2005) J Biol Chem, 7, pp. 840-846
Arnold, H.P., She, Q., Phan, H., Stedman, K., Prangishvili, D., Holz, I., Kristjansson, J.K., Zillig, W., The genetic elements pSSVx of the extremely thermophilic crenarchaeon Sulfolobus is a hybrid between a plasmid and a virus (1999) Mol Microbiol, 34, pp. 217-226
Bradford, M., A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal Biochem, 72, pp. 248-254
Weber, K., Pringle, J.R., Osborn, M., Measurement of molecular weight by electrophoresis on SDS-acrylamide gel (1972) Methods Enzymol, 26, pp. 3-27
Lim, Y.S., Cha, M.K., Kim, H.K., Uhm, T.B., Park, J.W., Kim, K., Kim, I.H., Removals of hydrogen peroxide and hydroxyl radical by thiol-specific antioxidant protein as a possible role in vivo (1993) Biochem Biophys Res Commun, 192, pp. 273-280
Sambrook, J., Fritsch, E.F., Maniatis, T., (1989) Molecular Cloning: A Laboratory Manual, 2nd Edn., , Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
Imaly, J. A., Pathways of oxidative damage (2003) Annu Rev Microbiol, 57, pp. 395-41
Rho, B. S., Hung, L. W., Holton, J. M., Vigil, D., Kim, S. I., Park, M. S., Terwilliger, T. C., Pedelacq, J. D., Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis (2006) J Mol Biol, 361, pp. 850-863
Jeon, S. J., Ishikawa, K., Characterization of novel hexadecameric thioredoxin peroxidase from Aeropyrum pernix K1 (2003) J Biol Chem, 278, pp. 24174-24180
Dietz, K. J., Jacob, S., Oelze, M. L., Laxa, M., Tognetti, V., De Miranda, S. M., Baier, M., Finkemeier, I., The function of peroxiredoxins in plant organelle redox metabolism (2006) J Exp Bot, 57, pp. 1697-1709
Wood, Z. A., Schroder, E., Robin, H. J., Poole, L. B., Structure, mechanism and regulation of peroxiredoxins (2003) Trends Biochem Sci, 28, pp. 32-40
Seaver, L. C., Imlay, J. A., Alkyl hydroperoxide reductase is the primary scavenger of endogenous hydrogen peroxide in Escherichia coli (2001) J Bacteriol, 183, pp. 7173-7181
She, Q., Singh, R. K., Confalonieri, F., Zivanovic, Y., Allard, G., Awayez, M. J., Chan-Weiher, C. C., De Moors, A., The complete genome of the crenarchaeon Sulfolobus solfataricus P2 (2001) Proc Natl Acad Sci USA, 98, pp. 7835-7840
Copley, S. D., Novak, W. R., Babbitt, P. C., Divergence of function in the thioredoxin fold suprafamily: Evidence for evolution of peroxiredoxins from a thioredoxin-like ancestor (2004) Biochemistry, 43, pp. 13981-13995
Arnold, H. P., She, Q., Phan, H., Stedman, K., Prangishvili, D., Holz, I., Kristjansson, J. K., Zillig, W., The genetic elements pSSVx of the extremely thermophilic crenarchaeon Sulfolobus is a hybrid between a plasmid and a virus (1999) Mol Microbiol, 34, pp. 217-226
Lim, Y. S., Cha, M. K., Kim, H. K., Uhm, T. B., Park, J. W., Kim, K., Kim, I. H., Removals of hydrogen peroxide and hydroxyl radical by thiol-specific antioxidant protein as a possible role in vivo (1993) Biochem Biophys Res Commun, 192, pp. 273-280
Febs Journal (ISSN: 1742-464x), 2008 May; 275(9): 2067-2077.
Tipo di articolo: Journal Article,
Impact factor: 3.139, Impact factor a 5 anni: 3.421
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-42449109092&partnerID=40&md5=052229611002e70c70b8a87a0d6f8af8
Parole chiave: Antioxidant, Archaea, Disulfide Oxidoreductase, Oxidative Stress, Thiol-Peroxidase, Bacterioferritin Comigratory Protein 1, Peroxiredoxin, Reduced Nicotinamide Adenine Dinucleotide Phosphate, Thioredoxin, Thioredoxin Reductase, Unclassified Drug, Aeropyrum, Amino Acid Sequence, Article, Bacterial Growth, Comparative Study, Controlled Study, Enzyme Activity, Escherichia Coli, Gene Amplification, Gene Expression, Genetic Transcription, In Vivo Study, Nonhuman, Northern Blotting, Priority Journal, Protein Analysis, Protein Purification, Sequence Analysis, Sulfolobus Solfataricus, Temperature Dependence, Thermostability, Bacterial Proteins, Cloning, Molecular, Cysteine, Escherichia Coli Proteins, Molecular Sequence Data, Molecular Weight, Nadph Oxidoreductases, Oxidation-Reduction, Plasmids, Protein Structure, Quaternary, Recombinant Proteins, Sequence Homology, Thioredoxin-Disulfide Reductase, Aeropyrum Pernix,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Biologia Strutturale e Funzionale, Complesso Universitario di Monte S. Angelo, Università di Napoli 'Federico II', Via Cinthia, 80126 Naples, Italy
Istituto di Biostrutture e Bioimmagini, CNR, Naples, Italy
Riferimenti:
Imaly, J.A., Pathways of oxidative damage (2003) Annu Rev Microbiol, 57, pp. 395-41
Rho, B.S., Hung, L.W., Holton, J.M., Vigil, D., Kim, S.I., Park, M.S., Terwilliger, T.C., Pedelacq, J.D., Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis (2006) J Mol Biol, 361, pp. 850-863
Jeon, S.J., Ishikawa, K., Characterization of novel hexadecameric thioredoxin peroxidase from Aeropyrum pernix K1 (2003) J Biol Chem, 278, pp. 24174-24180
Dietz, K.J., Jacob, S., Oelze, M.L., Laxa, M., Tognetti, V., De Miranda, S.M., Baier, M., Finkemeier, I., The function of peroxiredoxins in plant organelle redox metabolism (2006) J Exp Bot, 57, pp. 1697-1709
Wood, Z.A., Schroder, E., Robin, H.J., Poole, L.B., Structure, mechanism and regulation of peroxiredoxins (2003) Trends Biochem Sci, 28, pp. 32-40
Seaver, L.C., Imlay, J.A., Alkyl hydroperoxide reductase is the primary scavenger of endogenous hydrogen peroxide in Escherichia coli (2001) J Bacteriol, 183, pp. 7173-7181
Kashima, Y., Ishikawa, K., Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii (2003) J Biochem (Tokyo), 134, pp. 25-29
Kawakami, R., Sakuraba, H., Kamohara, S., Goda, S., Kawarabayasi, Y., Ohshima, T., Oxidative stress response in an anaerobic hyperthermophilic archaeon: Presence of a functional peroxiredoxin in Pyrococcus horikoshii (2004) J Biochem (Tokyo), 136, pp. 541-547
She, Q., Singh, R.K., Confalonieri, F., Zivanovic, Y., Allard, G., Awayez, M.J., Chan-Weiher, C.C., De Moors, A., The complete genome of the crenarchaeon Sulfolobus solfataricus P2 (2001) Proc Natl Acad Sci USA, 98, pp. 7835-7840
Ursby, T., Adinolfi, B.S., Al-Karadaghi, S., De Vendittis, E., Bocchini, V., Iron superoxide dismutase from the archaeon Sulfolobus solfataricus: Analysis of structure and thermostability (1999) J Mol Biol, 286, pp. 189-205
Limauro, D., Pedone, E., Pirone, L., Bartolucci, S., Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (2006) FEBS J, 273, pp. 721-731
De Vendittis, E., Ursby, T., Rullo, R., Gogliettino, M.A., Masullo, M., Bocchini, V., Phenylmethanesulfonyl fluoride inactivates an archaeal superoxide dismutase by chemical modification of a specific tyrosine residue. Cloning, sequencing and expression of the gene coding for Sulfolobus solfataricus superoxide dismutase (2001) Eur J Biochem, 268, pp. 1794-1801
Cannio, R., D'Angelo, A., Rossi, M., Bartolucci, S., A superoxide dismutase from the archaeon Sulfolobus solfataricus is an extracellular enzyme and prevents the deactivation by superoxide of cell-bound proteins (2000) Eur J Biochem, 267, pp. 235-243
Bini, E., Dikshit, V., Dirksen, K., Drozda, M., Blum, P., Stability of mRNA in the hyperthermophilic archaeon Sulfolobus solfataricus (2002) RNA, 8, pp. 1129-1136
Limauro, D., Fiorentino, G., Bartolucci, S., How Sulfolobus responds to enviromental stress (2004) Biochemistry and Molecular Biology in the Thermophilic Archaeon Sulfolobus Solfataricus, pp. 105-130. , In. Farina, B. Faraone Mennella, M.R., eds. pp. Research Signpost, Kerala, India
Pedone, E., D'Ambrosio, K., De Simone, G., Rossi, M., Pedone, C., Bartolucci, S., Insights on a new PDI-like family: Structural and functional analysis of a protein disulfide oxidoreductase from the bacterium Aquifex aeolicus (2006) J Mol Biol, 356, pp. 155-164
Pedone, E., Limauro, D., D'Alterio, R., Rossi, M., Bartolucci, S., Characterization of a multifunctional protein disulfide oxidoreductase from Sulfolobus solfataricus (2006) FEBS J, 273, pp. 5407-5420
Stork, T., Michel, K.P., Pistorius, E.K., Dietz, K.J., Bioinformatic analysis of the genomes of the cyanobacteria Synechocystis sp. PCC 6803 and Synechococcus elongatus PCC 7942 for the presence of peroxiredoxins and their transcript regulation under stress (2005) J Exp Bot, 56, pp. 3193-3206
Copley, S.D., Novak, W.R., Babbitt, P.C., Divergence of function in the thioredoxin fold suprafamily: Evidence for evolution of peroxiredoxins from a thioredoxin-like ancestor (2004) Biochemistry, 43, pp. 13981-13995
Hosoya-Matsuda, N., Motohashi, K., Yoshimura, H., Nozaki, A., Inoue, K., Ohmori, M., Hisabori, T., Anti-oxidative stress system in cyanobacteria. Significance of type II peroxiredoxin and the role of 1-Cys peroxiredoxin in Synechocystis sp. strain PCC 6803 (2005) J Biol Chem, 7, pp. 840-846
Arnold, H.P., She, Q., Phan, H., Stedman, K., Prangishvili, D., Holz, I., Kristjansson, J.K., Zillig, W., The genetic elements pSSVx of the extremely thermophilic crenarchaeon Sulfolobus is a hybrid between a plasmid and a virus (1999) Mol Microbiol, 34, pp. 217-226
Bradford, M., A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal Biochem, 72, pp. 248-254
Weber, K., Pringle, J.R., Osborn, M., Measurement of molecular weight by electrophoresis on SDS-acrylamide gel (1972) Methods Enzymol, 26, pp. 3-27
Lim, Y.S., Cha, M.K., Kim, H.K., Uhm, T.B., Park, J.W., Kim, K., Kim, I.H., Removals of hydrogen peroxide and hydroxyl radical by thiol-specific antioxidant protein as a possible role in vivo (1993) Biochem Biophys Res Commun, 192, pp. 273-280
Sambrook, J., Fritsch, E.F., Maniatis, T., (1989) Molecular Cloning: A Laboratory Manual, 2nd Edn., , Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
Imaly, J. A., Pathways of oxidative damage (2003) Annu Rev Microbiol, 57, pp. 395-41
Rho, B. S., Hung, L. W., Holton, J. M., Vigil, D., Kim, S. I., Park, M. S., Terwilliger, T. C., Pedelacq, J. D., Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis (2006) J Mol Biol, 361, pp. 850-863
Jeon, S. J., Ishikawa, K., Characterization of novel hexadecameric thioredoxin peroxidase from Aeropyrum pernix K1 (2003) J Biol Chem, 278, pp. 24174-24180
Dietz, K. J., Jacob, S., Oelze, M. L., Laxa, M., Tognetti, V., De Miranda, S. M., Baier, M., Finkemeier, I., The function of peroxiredoxins in plant organelle redox metabolism (2006) J Exp Bot, 57, pp. 1697-1709
Wood, Z. A., Schroder, E., Robin, H. J., Poole, L. B., Structure, mechanism and regulation of peroxiredoxins (2003) Trends Biochem Sci, 28, pp. 32-40
Seaver, L. C., Imlay, J. A., Alkyl hydroperoxide reductase is the primary scavenger of endogenous hydrogen peroxide in Escherichia coli (2001) J Bacteriol, 183, pp. 7173-7181
She, Q., Singh, R. K., Confalonieri, F., Zivanovic, Y., Allard, G., Awayez, M. J., Chan-Weiher, C. C., De Moors, A., The complete genome of the crenarchaeon Sulfolobus solfataricus P2 (2001) Proc Natl Acad Sci USA, 98, pp. 7835-7840
Copley, S. D., Novak, W. R., Babbitt, P. C., Divergence of function in the thioredoxin fold suprafamily: Evidence for evolution of peroxiredoxins from a thioredoxin-like ancestor (2004) Biochemistry, 43, pp. 13981-13995
Arnold, H. P., She, Q., Phan, H., Stedman, K., Prangishvili, D., Holz, I., Kristjansson, J. K., Zillig, W., The genetic elements pSSVx of the extremely thermophilic crenarchaeon Sulfolobus is a hybrid between a plasmid and a virus (1999) Mol Microbiol, 34, pp. 217-226
Lim, Y. S., Cha, M. K., Kim, H. K., Uhm, T. B., Park, J. W., Kim, K., Kim, I. H., Removals of hydrogen peroxide and hydroxyl radical by thiol-specific antioxidant protein as a possible role in vivo (1993) Biochem Biophys Res Commun, 192, pp. 273-280
Peroxiredoxins are ubiquitous enzymes that are part of the oxidative stress defense system. In the present study, we identified three peroxiredoxins [bacterioferritin comigratory protein (Bcp)1, Bcp3 and Bcp4] in the genome of the aerobic hyperthermophilic archaeon Sulfolobus solfataricus. Based on the cysteine residues conserved in the deduced aminoacidic sequence, Bcp1 and Bcp4 can be classified as 2-Cys peroxiredoxins and Bcp3 as a 1-Cys peroxiredoxin. A comparative study of the recombinant Bcps produced in Escherichia coli showed that these enzymes protect DNA plasmid from oxidative damage and remove both H2O2 and tert-butyl hydroperoxide, although at different efficiencies. We observed that all of them were particularly thermostable and that peak enzymatic activity fell within the range of the growth temperature of S. solfataricus. Furthermore, we discovered an alternative Bcp reduction system whose composition differs from that of the peroxiredoxin reduction system previously characterized in the aerobic hyperthermophilic archaeon Aeropyrum pernix. Whereas the latter uses the thioredoxin/thioredoxin reductase/NADPH system, this alternative Bcp system is formed of the protein disulfide oxidoreducatase, SSO0192, the thioredoxin reductase, SSO2416, and NADPH. The role of Bcps in oxidative stress was investigated using transcriptional analysis. Different northern blot analysis responses suggested that the Bcp antioxidant system of S. solfataricus can both operate at the constitutive level, with Bcp1 and Bcp4 preventing endogenous peroxide formation, and at the inducible level, with Bcp3 and the already characterized Bcp2 protecting cells from the attack of external peroxides.
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Impact Factor: 5.771
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Oliveri V, Attanasio F, Puglisi A, Spencer J, Sgarlata C, Vecchio G
* Multifunctional 8-hydroxyquinoline-appended cyclodextrins as new inhibitors of metal-induced protein aggregation (248 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2014 Jul 14; 20(29): 8954-8964.
Impact Factor: 5.731
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Pedone E, Fiorentino G, Pirone L, Contursi P, Bartolucci S, Limauro D
* Functional and structural characterization of protein disulfide oxidoreductase from Thermus thermophilus HB27 (183 visite)
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic), 2014 Jul; 18(4): 723-731.
Impact Factor: 2.306
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Limauro D, De Simone G, Pirone L, Bartolucci S, D'Ambrosio K, Pedone E
* Sulfolobus solfataricus thiol redox puzzle: characterization of an atypical protein disulfide oxidoreductase (183 visite)
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic), 2014 Mar; 18(2): 219-228.
Impact Factor: 2.306
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De Chiara L, Fagoonee S, Ranghino A, Bruno S, Camussi G, Tolosano E, Silengo L, Altruda F
* Renal cells from spermatogonial germline stem cells protect against kidney injury (107 visite)
J Am Soc Nephrol (ISSN: 1046-6673), 2014 Feb; 25(2): 316-328.
Impact Factor: 9.343
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Doti N, Reuther C, Scognamiglio PL, Dolga AM, Plesnila N, Ruvo M, Culmsee C
* Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress (200 visite)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2014 Jan 16; 5(1): e993-e993.
Impact Factor: 5.014
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Dathan NA, Alterio V, Troiano E, Vullo D, Ludwig M, De Simone G, Supuran CT, Monti SM
* Biochemical Characterization Of The Chloroplastic β-Carbonic Anhydrase From Flaveria Bidentis (l. ) "kuntze" (177 visite)
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2014; 29(4): 500-504.
Impact Factor: 2.332
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine and Cognitive Deficits (26 visite)
Diet And Nutr In Dement And Cogn Decline (ISSN: 9780-1240793979780124078246), 2014; N/D: 973-982.
Impact Factor: 0
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Messori L, Scaletti F, Massai L, Cinellu MA, Russo Krauss I, Di Martino G, Vergara A, Paduano L, Merlino A
* Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(III) compound (124 visite)
Metallomics (ISSN: 1756-5901, 1756-591x), 2014; 6(2): 233-236.
Impact Factor: 3.585
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Russo GL, Russo M, Spagnuolo C, Tedesco I, Bilotto S, Iannitti R, Palumbo R
* Quercetin: a pleiotropic kinase inhibitor against cancer (182 visite)
Cancer Treat Res (ISSN: 0927-3042), 2014; 159: 185-205.
Impact Factor: 9.284
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Bergamo P, Cocca E, Palumbo R, Gogliettino M, Rossi M, Palmieri G
* RedOx status, proteasome and APEH: Insights into anticancer mechanisms of t10, c12-conjugated linoleic acid isomer on A375 melanoma cells (202 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2013 Nov 19; 8(11): N/D-N/D.
Impact Factor: 3.534
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Savi L, Ribaldone DG, Fagoonee S, Pellicano R
* Is Helicobacter pylori the infectious trigger for headache?: A review (115 visite)
Infect Disord Drug Targets (ISSN: 2212-3989electronic, 1871-5265linking), 2013 Oct; 13(5): 313-317.
Impact Factor: 0
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Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A, Palumbo R, Nappo A, Iacomino G, Moio L, Russo GL
* Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line (177 visite)
Food Chem Toxicol (ISSN: 0278-6915), 2013; 60: 377-384.
Impact Factor: 2.61
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Del Giudice R, Monti DM, Truppo E, Arciello A, Supuran CT, De Simone G, Monti SM
* Human Carbonic Anhydrase Vii Protects Cells From Oxidative Damage (145 visite)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1431-1673, 1437-4315), 2013; 394(10): 1343-1348.
Impact Factor: 2.689
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Sorriento D, Fusco A, Ciccarelli M, Rungi A, Anastasio A, Carillo A, Dorn II GW, Trimarco B, Iaccarino G
* Mitochondrial G protein coupled receptor kinase 2 regulates proinflammatory responses in macrophages (152 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013; 587(21): 3487-3494.
Impact Factor: 3.341
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Forestier A, Douki T, Sauvaigo S, De Rosa V, Demeilliers C, Rachidi W
* Alzheimer's disease-associated neurotoxic peptide amyloid-beta impairs base excision repair in human neuroblastoma cells (183 visite)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2012 Nov 13; 13(11): 14766-14787.
Impact Factor: 2.464
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (202 visite)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Jul; 43(1): 153-163.
Impact Factor: 3.914
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Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
* Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity (196 visite)
Bba-Gen Subjects (ISSN: 0006-3002, 0925-4439, 1570-9639), 2012 May; 1822(5): 753-783.
Impact Factor: 3.733
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Truppo E, Supuran CT, Sandomenico A, Vullo D, Innocenti A, Di Fiore A, Alterio V, De Simone G, Monti SM
* Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors (175 visite)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2012 Feb 15; 22(4): 1560-1564.
Impact Factor: 2.338
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De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (142 visite)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
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Calabrese V, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ
* Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity (254 visite)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 279-304.
Impact Factor: 9.97
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (155 visite)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
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Rachidi W, De Rosa V
Selenium protects against the cytotoxic and genotoxic effects of oxidative stress both as an anti-oxidant and by stimulating DNA damage repair (109 visite)
Bulletin Du Cancer (ISSN: 0007-4551), 2011 Mar; 98: N/D-N/D.
Impact Factor: 0.672
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (163 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
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Spina-Purrello V, Giliberto S, Barresi V, Nicoletti VG, Giuffrida Stella AM, Rizzarelli E
* Modulation of PARP-1 and PARP-2 expression by L-carnosine and trehalose after LPS and INFγ-induced oxidative stress (197 visite)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2010 Dec; 35(12): 2144-2153.
Impact Factor: 2.608
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Pedone E, Limauro D, D'Ambrosio K, De Simone G, Bartolucci S
* Multiple catalytically active thioredoxin folds: a winning strategy for many functions (203 visite)
Cell Mol Life Sci Cellular And Molecular Life Sciences (ISSN: 1420-682x), 2010 Nov; 67(22): 3797-3814.
Impact Factor: 7.047
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Perrino C, Feliciello A, Schiattarella GG, Esposito G, Guerriero R, Zaccaro L, Del Gatto A, Saviano M, Garbi C, Carangi R, Di Lorenzo E, Donato G, Indolfi C, Avvedimento VE, Chiariello M
* AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress (194 visite)
Cardiovascular Research (ISSN: 0008-6363), 2010 Oct; 88(1): 101-110.
Impact Factor: 6.051
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Limauro D, D'Ambrosio K, Langella E, De Simone G, Galdi I, Pedone C, Pedone E, Bartolucci S
* Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus (135 visite)
Biochimie (ISSN: 1638-6183, 0300-9084, 1638-6183electronic), 2010 Oct; 92(10): 1435-1444.
Impact Factor: 3.787
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Erkekoǧlu P, Rachidi W, De Rosa V, Giray B, Favier A, Hincal F
* Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells (135 visite)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2010 Aug 15; 49(4): 559-566.
Impact Factor: 5.707
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Castellano I, Merlino A, Rossi M, La Cara F
* Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity (236 visite)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2010 May; 92(5): 464-474.
Impact Factor: 3.787
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De Rosa V, Diamond A, Favier A, Douki T, Rachidi W
* Effect of selenium on lethal and genotoxic properties of oxidative stress (106 visite)
Bulletin Du Cancer (ISSN: 0007-4551), 2010 Mar; 97: N/D-N/D.
Impact Factor: 0.887
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Pedone E, Limauro D, Bartolucci S
* Erratum: The machinery for oxidative protein folding in thermophiles (Antioxidants and Redox Signaling (2008) 10 (157-169)) (113 visite)
Antioxid Redox Signal (ISSN: 1523-0864, 1557-7716), 2010; 12(1): 171-179.
Impact Factor: 8.209
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Scir A, Pedone E, Ausili A, Saviano M, Baldassarre M, Bertoli E, Bartolucci S, Tanfani F
* High hydrostatic pressure-induced conformational changes in protein disulfide oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus. A Fourier-transform infrared spectroscopic study (142 visite)
Molecular Biosystems (ISSN: 1742-206x), 2010; 6(10): 2015-2022.
Impact Factor: 3.825
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Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E
* Carnosinase levels in aging brain: redox state induction and cellular stress response (174 visite)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864), 2009 Nov; 11(11): 2759-2775.
Impact Factor: 7.581
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Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA
* Nitric oxide in cell survival: a janus molecule (157 visite)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864), 2009 Nov; 11(11): 2717-2739.
Impact Factor: 7.581
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D'Ambrosio K, Limauro D, Pedone E, Galdi I, Pedone C, Bartolucci S, De Simone G
* Insights into the catalytic mechanism of the Bcp family: functional and structural analysis of Bcp1 from Sulfolobus solfataricus (174 visite)
Proteins (ISSN: 1097-0134, 0887-3585, 1097-0134electronic), 2009 Sep; 76(4): 995-1006.
Impact Factor: 3.085
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De Rosa V, Alan D, Alain F, Thierry D, Walid R
* The anticancer effect of selenium: study of its role in DNA repair activity and resistance to oxidative stress (114 visite)
Bulletin Du Cancer (ISSN: 0007-4551), 2009 Mar; 96: N/D-N/D.
Impact Factor: 0.792
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Calabrese V, Cornelius C, Mancuso C, Barone E, Calafato S, Bates T, Rizzarelli E, Kostova AT
* Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases (203 visite)
Frontiers In Bioscience (ISSN: 1093-4715, 1093-9946), 2009 Jan 1; 14: 376-397.
Impact Factor: 3.736
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Limauro D, Saviano M, Galdi I, Rossi M, Bartolucci S, Pedone E
* Sulfolobus solfataricus protein disulphide oxidoreductase: insight into the roles of its redox sites (101 visite)
Protein Engineering Design & Selection (ISSN: 1741-0126), 2009 Jan; 22(1): 19-26.
Impact Factor: 2.596
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Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
* Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (326 visite)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2008 Dec; 33(12): 2444-2471.
Impact Factor: 2.26
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Esposito L, Seydel A, Aiello R, Sorrentino G, Cendron L, Zanotti G, Zagari
* The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension (133 visite)
Bba-Mol Basis Dis (ISSN: 1570-9639, 0006-3002, 0925-4439), 2008 Nov; 1784(11): 1601-1606.
Impact Factor: 2.233
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Gustavsson T, Banyasz A, Sarkar N, Markovitsi D, Improta R
* Statin: New life for an old drug (151 visite)
Pharmacol Res Academic Press, 2008 Jun 23; 350(1-3): 1-2.
Impact Factor: 3.976
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Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (193 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
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Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (157 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
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Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (257 visite)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
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Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
* Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates (151 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.
Impact Factor: 2.301
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Cuzzocrea S, Genovese T, Failla M, Vecchio G, Fruciano M, Mazzon E, Di Paola R, Muià C, La Rosa C, Crimi N, Rizzarelli E, Vancheri C
* Protective effect of orally administered carnosine on bleomycin-induced lung injury (188 visite)
Am J Physiol Lung Cell Mol Physiol (ISSN: 1040-0605), 2007 May; 292(5): L1095-L1095.
Impact Factor: 4.214
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Bellia F, La Mendola D, Maccarrone G, Mineo P, Vitalini D, Scamporrino E, Sortino S, Vecchio G, Rizzarelli E
* Copper(II) Complexes With Beta-Cyclodextrin-Homocarnosine Conjugates And Their Antioxidant Activity (129 visite)
Inorg Chim Acta (ISSN: 0020-1693), 2007 Feb 15; 360(3): 945-954.
Impact Factor: 1.713
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Ronga L, Palladino P, Costantini S, Facchiano A, Ruvo M, Benedetti E, Ragone R, Rossi F
* Conformational diseases and structure-toxicity relationships: Lessons from prion-derived peptides (214 visite)
Curr Protein Pept Sci (ISSN: 1389-2037), 2007 Feb; 8(1): 83-90.
Impact Factor: 3.259
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Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T
* Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage (183 visite)
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2007 Jan 12; 282(2): 831-835.
Impact Factor: 5.581
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Pedone E, Limauro D, D'Alterio R, Rossi M, Bartolucci S
* Characterization of a multifunctional protein disulfide oxidoreductase from Sulfolobus solfataricus (111 visite)
Febs Journal (ISSN: 1742-464x), 2006 Dec; 273(23): 5407-5420.
Impact Factor: 3.033
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D'Ambrosio K, Pedone E, Langella E, De Simone G, Rossi M, Pedone C, Bartolucci S
* A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: Structure, function and electrostatics (130 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2006 Sep 29; 362(4): 743-752.
Impact Factor: 4.89
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Pedone E, D'Ambrosio K, De Simone G, Rossi M, Pedone C, Bartolucci S
* Insights on a new PDI-like family: Structural and functional analysis of a protein disulfide oxidoreductase from the bacterium Aquifex aeolicus (180 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2006 Feb 10; 356(1): 155-164.
Impact Factor: 4.89
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Palumbo R, Capasso D, Brescia F, Mita P, Sarti M, Bersani F, Scarfi MR
* Effects on apoptosis and reactive oxygen species formation by Jurkat cells exposed to 50 Hz electromagnetic fields (102 visite)
Bioelectromagnetics (ISSN: 0197-8462), 2006 Feb; 27(2): 159-162.
Impact Factor: 1.514
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Limauro D, Pedone E, Pirone L, Bartolucci S
* Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (133 visite)
Febs Journal (ISSN: 1742-464x), 2006 Feb; 273(4): 721-731.
Impact Factor: 3.033
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Pedone E, Saviano M, Bartolucci S, Rossi M, Ausili A, Scire A, Bertoli E, Tanfani F
* Temperature-, SDS-, and pH-induced conformational changes in protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: A dynamic simulation and fourier transform infrared spectroscopic study (117 visite)
J Proteome Res (ISSN: 1535-3893), 2005 Nov; 4(6): 1972-1980.
Impact Factor: 6.901
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Calabrese V, Colombrita C, Guagliano E, Sapienza M, Ravagna A, Cardile V, Scapagnini G, Santoro AM, Mangiameli A, Butterfield DA, Giuffrida Stella AM, Rizzarelli E
* Protective effect of carnosine during nitrosative stress in astroglial cell cultures (162 visite)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2005 Jun; 30(6-7): 797-807.
Impact Factor: 2.187
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D'Ambrosio K, De Simone G, Pedone E, Rossi M, Bartolucci S, Pedone C
* Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aeropyrum pernix K1 (132 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2005 Mar 1; 61(3): 335-336.
Impact Factor: 0.568
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Tedesco I, Nappo A, Petitto F, Iacomino G, Nazzaro F, Palumbo R, Russo Gian L
* Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line (173 visite)
Nutr Cancer (ISSN: 0163-5581), 2005; 52(1): 74-83.
Impact Factor: 2.426
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Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (129 visite)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
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D'Ambrosio K, De Simone G, Pedone E, Rossi M, Bartolucci S, Pedone C
* Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aquifex aeolicus (118 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2004 Nov; 60(11): 2076-2077.
Impact Factor: 1.693
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Pedone E, Bartolucci S, Fiorentino G
* Sensing and adapting to environmental stress: The Archaeal tactic (127 visite)
Frontiers In Bioscience (ISSN: 1093-9946, 1093-4715), 2004 Sep 1; 9: 2909-2926.
Impact Factor: 3.226
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Pedone E, Ren B, Ladenstein R, Rossi M, Bartolucci S
* Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus - A member of a novel protein family related to protein disulfide-isomerase (136 visite)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print), 2004 Sep; 271(16): 3437-3448.
Impact Factor: 3.26
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Caridi A, Cufari A, Lovino R, Palumbo R, Tedesco I
* Influence of Yeast on Polyphenol Composition of Wine (99 visite)
Food Technol Biotechnol (ISSN: 1330-9862), 2004 Jan; 42(1): 37-40.
Impact Factor: 0.475
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Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (180 visite)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
Dettagli Esporta in BibTeX Esporta in EndNote
Bonomo RP, Bruno V, Conte E, De Guidi G, La Mendola D, Maccarrone G, Nicoletti F, Rizzarelli E, Sortino S, Vecchio G
* Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (182 visite)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2003; (23): 4406-4415.
Impact Factor: 2.908
Dettagli Esporta in BibTeX Esporta in EndNote
Tabbì G, Cassino C, Cavigiolio G, Colangelo D, Ghiglia A, Viano I, Osella D
* Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process (223 visite)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2002 Dec 19; 45(26): 5786-5796.
Impact Factor: 4.566
Dettagli Esporta in BibTeX Esporta in EndNote
Borrelli RC, Fogliano V, Monti SM, Ames JM
* Characterization of melanoidins from a glucose-glycine model system (122 visite)
Eur Food Res Technol (ISSN: 1438-2377), 2002 Sep; 215(3): 210-215.
Impact Factor: 1.021
Dettagli Esporta in BibTeX Esporta in EndNote
Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (158 visite)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
Dettagli Esporta in BibTeX Esporta in EndNote
Monti SM, Ritieni A, Sacchi R, Skog K, Borgen E, Fogliano V
* Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system (173 visite)
J Agric Food Chem (ISSN: 0021-8561), 2001 Sep; 49(8): 3969-3975.
Impact Factor: 1.576
Dettagli Esporta in BibTeX Esporta in EndNote
Ogawa R, Pacelli R, Espey MG, Miranda KM, Friedman N, Kim SM, Cox G, Mitchell JB, Wink DA, Russo A
* Comparison of control of Listeria by nitric oxide redox chemistry from murine macrophages and no donors: Insights into listeriocidal activity of oxidative and nitrosative stress (202 visite)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2001 Feb 1; 30(3): 268-276.
Impact Factor: 5.082
Dettagli Esporta in BibTeX Esporta in EndNote
Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (142 visite)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
Dettagli Esporta in BibTeX Esporta in EndNote
Monti SM, Borrelli RC, Ritieni A, Fogliano V
A comparison of color formation and Maillard reaction products of a lactose-lysine and lactose-N(α)-acetyllysine model system (156 visite)
J Agric Food Chem (ISSN: 0021-8561), 2000; 48(4): 1041-1046.
Impact Factor: 1.56
Dettagli Esporta in BibTeX Esporta in EndNote
Fogliano V, Ritieni A, Monti SM, Gallo M, Della Medaglia D, Ambrosino ML, Sacchi R
Antioxidant activity of virgin olive oil phenolic compounds in a micellar system (127 visite)
Journal Of The Science Of Food And Agriculture (ISSN: 0022-5142), 1999 Oct; 79(13): 1803-1808.
Impact Factor: 1.097
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Vodovotz Y, Grisham MB, DeGraff W, Cook JC, Pacelli R, Krishna M, Mitchell JB
Antioxidant effects of nitric oxide (141 visite)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic), 1998; 301: 413-424.
Impact Factor: 2.823
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Cook JA, Kim SY, Vodovotz Y, Pacelli R, Krishna MC, Russo A, Mitchell JB, Jourd'heuil D, Miles AM, Grisham MB
Superoxide modulates the oxidation and nitrosation of thiols by nitric oxide-derived reactive intermediates (109 visite)
J Biol Chem (ISSN: 0021-9258, 1083-351x), 1997 Apr 25; 272(17): 11147-11151.
Impact Factor: 6.963
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Cook JA, Pacelli R, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection (170 visite)
Arch Biochem Biophys (ISSN: 0003-9861), 1996 Jul 15; 331(2): 241-248.
Impact Factor: 2.649
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Hanbauer I, Grisham MB, Laval F, Nims RW, Laval J, Cook J, Pacelli R, Liebmann J, Krishna M, Ford PC, Mitchell JB
Chemical biology of nitric oxide: Regulation and protective and toxic mechanisms (123 visite)
Current Topics In Cellular Regulation (ISSN: 0070-2137), 1996; 34: 159-187.
Impact Factor: 4.375
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (169 visite)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Cook JA, Pacelli R, Liebmann J, Krishna MC, Mitchell JB
Nitric oxide (NO) protects against cellular damage by reactive oxygen species (156 visite)
Toxicology Letters (ISSN: 0378-4274), 1995 Dec; 82-3: 221-226.
Impact Factor: 1.128
Dettagli Esporta in BibTeX Esporta in EndNote
Bonomo RP, De Flora A, Rizzarelli E, Santoro AM, Tabbì G, Tonetti M
Copper(II) complexes encapsulated in human red blood cells (181 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Sep; 59(4): 773-784.
Impact Factor: 1.342
Dettagli Esporta in BibTeX Esporta in EndNote
Costanzo LL, De Guidi G, Giuffrida S, Sortino S, Condorelli G, Pappalardo G
Antioxidant effect of copper(II) on photosensitized lipid peroxidation (168 visite)
J Chem Res (ISSN: 0162-0134print, 0162-0134linking, 1873-3344), 1995 Feb; 57(2): 115-125.
Impact Factor: 1.342
Dettagli Esporta in BibTeX Esporta in EndNote
Condorelli G, Costanzo LL, De Guidi G, Giuffrida S, Rizzarelli E, Vecchio G
INHIBITION OF PHOTOHEMOLYSIS BY COPPER(II) COMPLEXES WITH SOD-LIKE ACTIVITY (170 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1994 Jun; 54(4): 257-265.
Impact Factor: 1.342
Dettagli Esporta in BibTeX Esporta in EndNote
96 Records (90 escludendo Abstract e Conferenze).
Impact factor totale: 356.307 (332.86 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 385.33 (358.763 escludendo Abstract e Conferenze).
Impact factor totale: 356.307 (332.86 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 385.33 (358.763 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
Ultima modifica di Marco Comerci in data Thursday 19 March 2015, 13:24:11
171 visite. Ultima visita in data Saturday 09 November 2019, 4:19:14
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