Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates

Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates (145 visite)

Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G

Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.

Tipo di articolo: Journal Article, Research Support, Non-U. S. Gov'T,

Impact factor: 2.301, Impact factor a 5 anni: 2.548

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-34250160541&partnerID=40&md5=a65d0b29e2713290019cc8a607581f9a

Parole chiave: β-Cylodextrin, Carnosine, Homocarnosine, Low Density Lipoprotein, Pulse Radiolysis, 3a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl)ethyl]amino] 4 Oxobutyl]amino] 3a Deoxy Beta Cyclodextrin, 6a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl)ethyl]amino] 4 Oxobutyl]amino] 6a Deoxy Beta Cyclodextrin, Cupric Ion, Reactive Oxygen Metabolite, Scavenger, Unclassified Drug, Antioxidant Activity, Article, Controlled Study, Drug Activity, Drug Structure, Drug Synthesis, Human, In Vitro Study, In Vivo Study, Nuclear Magnetic Resonance, Oxidation, Beta-Cyclodextrins, Hydrogen-Ion Concentration, Magnetic Resonance Spectroscopy, Molecular Structure, Oxidation-Reduction, 3a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl) Ethyl] Amino] 4 Oxobutyl] Amino] 3a Deoxy Beta Cyclodextrin, 6a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl) Ethyl] Amino] 4 Oxobutyl] Amino] 6a Deoxy Beta Cyclodextrin,

Affiliazioni:

*** IBB - CNR ***
Dipartimento di Scienze Chimiche, Università di Catania, V.le A. Doria 6, 95125 Catania, Italy
Istituto di Biochimica, Biochimica Clinica, Università Cattolica Sacro Cuore, Largo F. Vito 1, 00164 Roma, Italy
Istituto di Biostrutture e Bioimmagini, CNR, Catania, V.le A. Doria 6, 95125 Catania, Italy

Riferimenti:

Szejtli, J., (1998) Chem. Rev., 98, pp. 1743-175

Pralhad, T., Rajendrakumar, K., (2004) J. Pharm. Biomed. Anal., 34, pp. 333-339

Uekama, K., (2004) Chem. Pharm. Bull., 52, pp. 900-915

Di Blasio, B., Pavone, V., Nastri, F., Isernia, C., Saviano, M., Pedone, C., Cucinotta, V., Vecchio, G., (1992) Proc. Natl. Acad. Sci. USA, 89, pp. 7218-7221

Djedaini-Pilard, F., Desalos, J., Perly, B., (1993) Tetrahedron Lett., 34, pp. 2457-2460

Fernandez, M., Fragoso, A., Cao, R., Banos, M., Ansorge-Schumacher, M., Hartmeier, W., Villalonga, R., (2004) J. Mol. Catal. B Enzym., 31, pp. 47-52

Hristova-Kazmierski, M.K., Horan, P., Davis, P., Yamamura, H.I., Kramer, T., Horvath, R., Kazmierski, W.M., Hruby, V.J., (1993) Bioorg. Med. Chem. Lett., 3, pp. 831-834

Parrot-Lopez, H., Djedaini, F., Perly, B., Coleman, A.W., Galons, H., Miocque, M., (1990) Tetrahedron Lett., 31, pp. 1999-2002

Pean, C., Creminon, C., Wijkhuisen, A., Grassi, J., Guenot, P., Jehan, P., Dalbiez, J.-P., Djedaini-Pilard, F., (2000) J. Chem. Soc. Perkin Trans., 2, pp. 853-863

Schaschke, N., Fiori, S., Weyher, E., Escrieut, C., Fourmy, D., Mueller, G., Moroder, L., (1998) J. Am. Chem. Soc., 120, pp. 7030-7038

Boldyrev, A.A., Johnson, P., (2002) Oxidative Stress at Molecular, Cellular and Organ Levels, pp. 101-113. , Boldyrev A.A., and Johnson P. (Eds), Research Signpost, India

Skulachev, V.P., (2000) Biochemistry (Mosc), 65, pp. 749-750

Tabakman, R., Lazarovici, P., Kohen, R., (2002) J. Neurosci. Res., 68, pp. 463-469

Mzhelskaya, T.I., Boldyrev, A.A., (1999) Neirokhimiya, 16, pp. 133-144

Petroff, O.A., Hyder, F., Mattson, R.H., Rothman, D.L., (1999) Neurology, 52, pp. 473-478

Guiotto, A., Calderan, A., Ruzza, P., Borin, G., (2005) Curr. Med. Chem., 12, pp. 2293-2315

Teufel, M., Saudek, V., Ledig, J.-P., Bernhardt, A., Boularand, S., Carreau, A., Cairns, N.J., Smirnova, T., (2003) J. Biol. Chem., 278, pp. 6521-6531

Bonomo, R.P., Bruno, V., Conte, E., De Guidi, G., La Mendola, D., Maccarrone, G., Nicoletti, F., Vecchio, G., (2003) J. Chem. Soc. Dalton Trans., pp. 4406-4415

La Mendola, D., Sortino, S., Vecchio, G., Rizzarelli, E., (2002) Helv. Chim. Acta, 85, pp. 1633-1643

Bonomo, R.P., Cucinotta, V., D'Alessandro, F., Impellizzeri, G., Maccarrone, G., Vecchio, G., Rizzarelli, E., (1991) Inorg. Chem., 30, pp. 2708-2713

Teranishi, K., Watanabe, K., Hisamatsu, M., Yamada, T., (1998) J. Carbohydr. Chem., 17, pp. 489-494

Mulazzani, Q.G., D'Angelantonio, M., Venturi, M., Hoffman, M.Z., Rodgers, M.A.J., (1986) J. Phys. Chem., 90, pp. 5347-5352

Lazzarino, G., Di Pierro, D., Tavazzi, B., Cerroni, L., Giardina, B., (1991) Anal. Biochem., 197, pp. 191-196

Donze, C., Rizzarelli, E., Vecchio, G., (1998) Supramol. Chem., 10, pp. 33-42

Vecchio, G., La Mendola, D., Rizzarelli, E., (2001) J. Supramol. Chem., 1, pp. 87-95

Di Blasio, B., Galdiero, S., Saviano, M., Pedone, C., Benedetti, E., Rizzarelli, E., Pedotti, S., Gibbons, W.A., (1996) Carbohydr. Res., 282, pp. 41-52

Bonomo, R.P., Maccarrone, G., Rizzarelli, E., Vecchio, G., (2002) Inorg. Chim. Acta, 339, pp. 455-460

Cucinotta, V., Giuffrida, A., La Mendola, D., Maccarrone, G., Puglisi, A., Rizzarelli, E., Vecchio, G., (2004) J. Chromatogr. B Anal. Technol. Biomed. Life Sci., 800, pp. 127-133

Nogami, Y., Nasu, K., Koga, T., Ohta, K., Fujita, K., Immel, S., Lindner, H.J., Lichtenthaler, F.W., (1997) Angew. Chem. Int. Ed. Engl., 36, pp. 1899-1902

Chen, W.-H., Yuan, D.-Q., Fujita, K., (1996) Tetrahedron Lett., 37, pp. 7561-7564

Fujita, K., Chen, W.-H., Yuan, D.-Q., Nogami, Y., Koga, T., Fujioka, T., Mihashi, K., Lichtenthaler, F.W., (1999) Tetrahedron: Asymmetry, 10, pp. 1689-1696

Fujita, K., Ohta, K., Ikegami, Y., Shimada, H., Tahara, T., Nogami, Y., Koga, T., Nakajima, T., (1994) Tetrahedron Lett., 35, pp. 9577-9580

Buxton, G.V., Greenstock, C.L., Helman, W.P., Ross, A.B., (1988) J. Phys. Chem. Ref. Data, 17, pp. 513-886

Tamba, M., Torreggiani, A., (1998) Int. J. Radiat. Biol., 74, pp. 333-340

Bansal, K.M., Sellers, R.M., (1975) J. Phys. Chem., 79, pp. 1775-1780

Tsimikas, S., (2006) Curr. Atheroscler. Rep., 8, pp. 55-61

Patel, R.P., Darley-Usmar, V.M., (1999) Free Radic. Res., 30, pp. 1-9

Kuzuya, M., Yamada, K., Hayashi, T., Funaki, C., Naito, M., Asai, K., Kuzuya, F., (1992) Biochim. Biophys. Acta, 1123, pp. 334-341

Decker, E.A., Ivanov, V., Zhu, B.Z., Frei, B., (2001) J. Agric. Food Chem., 49, pp. 511-516

Sovago, I., Farkas, E., Bertalan, C., Lebkiri, A., Kowalik-Jankowska, T., Kozlowski, H., (1993) J. Inorg. Biochem., 51, pp. 715-726

Kritharides, L., Kus, M., Brown, A.J., Jessup, W., Dean, R.T., (1996) J. Biol. Chem., 271, pp. 27450-27455

Giessauf, A., Steiner, E., Esterbauer, H., (1995) Biochim. Biophys. Acta, 1256, pp. 221-232

Aachmann, F.L., Otzen, D.E., Larsen, K.L., Wimmer, R., (2003) Protein Eng., 16, pp. 905-912

Song, L.X., Teng, C.F., Yang, Y., (2006) J. Incl. Phenom. Macr. Chem., 54, pp. 221-232

Yi, Z., Qasim, M.A., Qasim, S., Warrington, T.L., Laskowski Jr., M., (2006) Biochim. Biophys. Acta, 1760, pp. 372-379

Boldyrev, A., Bulygina, E., Leinsoo, T., Petrushanko, I., Tsubone, S., Abe, H., (2004) Comp. Biochem. Physiol. Biochem. Mol. Biol., 137, pp. 81-88

Boldyrev, A. A., Johnson, P., (2002) Oxidative Stress at Molecular, Cellular and Organ Levels, pp. 101-113. , Boldyrev A. A., and Johnson P. (Eds), Research Signpost, India

Skulachev, V. P., (2000) Biochemistry (Mosc), 65, pp. 749-750

Mzhelskaya, T. I., Boldyrev, A. A., (1999) Neirokhimiya, 16, pp. 133-144

Petroff, O. A., Hyder, F., Mattson, R. H., Rothman, D. L., (1999) Neurology, 52, pp. 473-478

Bonomo, R. P., Bruno, V., Conte, E., De Guidi, G., La Mendola, D., Maccarrone, G., Nicoletti, F., Vecchio, G., (2003) J. Chem. Soc. Dalton Trans., pp. 4406-4415

Bonomo, R. P., Cucinotta, V., D'Alessandro, F., Impellizzeri, G., Maccarrone, G., Vecchio, G., Rizzarelli, E., (1991) Inorg. Chem., 30, pp. 2708-2713

Mulazzani, Q. G., D'Angelantonio, M., Venturi, M., Hoffman, M. Z., Rodgers, M. A. J., (1986) J. Phys. Chem., 90, pp. 5347-5352

Bonomo, R. P., Maccarrone, G., Rizzarelli, E., Vecchio, G., (2002) Inorg. Chim. Acta, 339, pp. 455-460

Chen, W. -H., Yuan, D. -Q., Fujita, K., (1996) Tetrahedron Lett., 37, pp. 7561-7564

Buxton, G. V., Greenstock, C. L., Helman, W. P., Ross, A. B., (1988) J. Phys. Chem. Ref. Data, 17, pp. 513-886

Bansal, K. M., Sellers, R. M., (1975) J. Phys. Chem., 79, pp. 1775-1780

Patel, R. P., Darley-Usmar, V. M., (1999) Free Radic. Res., 30, pp. 1-9

Decker, E. A., Ivanov, V., Zhu, B. Z., Frei, B., (2001) J. Agric. Food Chem., 49, pp. 511-516

Aachmann, F. L., Otzen, D. E., Larsen, K. L., Wimmer, R., (2003) Protein Eng., 16, pp. 905-912

Song, L. X., Teng, C. F., Yang, Y., (2006) J. Incl. Phenom. Macr. Chem., 54, pp. 221-232

Yi, Z., Qasim, M. A., Qasim, S., Warrington, T. L., Laskowski Jr., M., (2006) Biochim. Biophys. Acta, 1760, pp. 372-379

Several in vitro and in vivo studies have suggested that carnosine (β-alanil-l-histidine) and homocarnosine (β-aminobutyril-l-histidine) can act as scavengers of reactive oxygen species. β-Cyclodextrin was functionalized with homocarnosine, obtaining the following new bioconjugate isomers: 6A-[(4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}-4-oxobutyl)amino]-6A-deoxy-β-cyclodextrin and (2AS,3AR)-3A-[(4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}-4-oxobutyl)amino]-3A-deoxy-β-cyclodextrin. Pulse radiolysis investigations show that the β-cyclodextrin homocarnosine bioconjugates are scavengers of {radical dot}OH radicals because of the formation of stable imidazole-centered radicals and the scavenger ability of glucose molecules of the macrocycle. The ability of these new β-cyclodextrin derivatives to inhibit the copper(II) driven LDL oxidation was determined in comparison with that displayed by the analogous carnosine derivatives. Both the β-cyclodextrin carnosine isomers show a higher protective effect than that of free dipeptide and homocarnosine derivatives, bringing into light the role of the β-CD cavity. The ability of these new β-cyclodextrin derivatives to inhibit the copper(II) driven LDL oxidation was determined in comparison with that displayed by the analogous carnosine derivatives. Both the β-cyclodextrin carnosine isomers show a higher protective effect than that of free dipeptide and homocarnosine derivatives, bringing into light the role of the β-CD cavity. © 2007 Elsevier Masson SAS. All rights reserved.

Interrogazione effettuata: [atitle, keywords] "β-Cylodextrin" OR [atitle, keywords] "Carnosine" OR [atitle, keywords] "Homocarnosine" OR [atitle, keywords] "Low Density Lipoprotein" OR [atitle, keywords] "Pulse Radiolysis" OR [atitle, keywords] "3a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl)ethyl]amino] 4 Oxobutyl]amino] 3a Deoxy Beta Cyclodextrin" OR [atitle, keywords] "6a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl)ethyl]amino] 4 Oxobutyl]amino] 6a Deoxy Beta Cyclodextrin"

Nessun risultato.

Interrogazione effettuata: [ptitle] "β-Cylodextrin" OR [ptitle] "Carnosine" OR [ptitle] "Homocarnosine" OR [ptitle] "Low Density Lipoprotein" OR [ptitle] "Pulse Radiolysis" OR [ptitle] "3a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl)ethyl]amino] 4 Oxobutyl]amino] 3a Deoxy Beta Cyclodextrin" OR [ptitle] "6a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl)ethyl]amino] 4 Oxobutyl]amino] 6a Deoxy Beta Cyclodextrin"

Nessun risultato.

Interrogazione effettuata: [btitle, keywords] "β-Cylodextrin" [btitle, keywords] "Carnosine" [btitle, keywords] "Homocarnosine" [btitle, keywords] "Low Density Lipoprotein" [btitle, keywords] "Pulse Radiolysis" [btitle, keywords] "3a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl)ethyl]amino] 4 Oxobutyl]amino] 3a Deoxy Beta Cyclodextrin" [btitle, keywords] "6a [[4 [[1 Carboxy 2 (1h Imidazol 4 Yl)ethyl]amino] 4 Oxobutyl]amino] 6a Deoxy Beta Cyclodextrin"

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Impact Factor: 3.226
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La Mendola D, Bonomo RP, Caminati S, Di Natale G, Emmi SS, Hansson O, Maccarrone G, Pappalardo G, Pietropaolo A, Rizzarelli E
* Copper(II) complexes with an avian prion N-terminal region and their potential SOD-like activity (164 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2009 Feb; 103(2): 195-204.
Impact Factor: 3.252
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Calabrese V, Cornelius C, Mancuso C, Barone E, Calafato S, Bates T, Rizzarelli E, Kostova AT
* Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases (194 visite)
Frontiers In Bioscience (ISSN: 1093-4715, 1093-9946), 2009 Jan 1; 14: 376-397.
Impact Factor: 3.736
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Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
* Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (316 visite)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2008 Dec; 33(12): 2444-2471.
Impact Factor: 2.26
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Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (187 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
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Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (246 visite)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
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Nicoletti VG, Santoro AM, Grasso G, Vagliasindi LI, Giuffrida ML, Cuppari C, Purrello VS, Stella AMG, Rizzarelli E
* Carnosine interaction with nitric oxide and astroglial cell protection (296 visite)
Journal Of Neuroscience Research (ISSN: 0360-4012), 2007 Sep 1; 85(10): 2239-2245.
Impact Factor: 3.268
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Cuzzocrea S, Genovese T, Failla M, Vecchio G, Fruciano M, Mazzon E, Di Paola R, Muià C, La Rosa C, Crimi N, Rizzarelli E, Vancheri C
* Protective effect of orally administered carnosine on bleomycin-induced lung injury (173 visite)
Am J Physiol Lung Cell Mol Physiol (ISSN: 1040-0605), 2007 May; 292(5): L1095-L1095.
Impact Factor: 4.214
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Bellia F, La Mendola D, Maccarrone G, Mineo P, Vitalini D, Scamporrino E, Sortino S, Vecchio G, Rizzarelli E
* Copper(II) Complexes With Beta-Cyclodextrin-Homocarnosine Conjugates And Their Antioxidant Activity (123 visite)
Inorg Chim Acta (ISSN: 0020-1693), 2007 Feb 15; 360(3): 945-954.
Impact Factor: 1.713
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Calabrese V, Colombrita C, Guagliano E, Sapienza M, Ravagna A, Cardile V, Scapagnini G, Santoro AM, Mangiameli A, Butterfield DA, Giuffrida Stella AM, Rizzarelli E
* Protective effect of carnosine during nitrosative stress in astroglial cell cultures (147 visite)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2005 Jun; 30(6-7): 797-807.
Impact Factor: 2.187
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La Rosa C, Milardi D, Amato E, Pappalardo M, Grasso D
* Molecular mechanism of the inhibition of cytochrome c aggregation by Phe-Gly (229 visite)
Arch Biochem Biophys (ISSN: 0003-9861), 2005 Mar 1; 435(1): 182-189.
Impact Factor: 3.152
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Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (158 visite)
Clin Nutr (ISSN: 0261-5614), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
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Mineo P, Vitalini D, La Mendola D, Rizzarelli E, Scamporrino E, Vecchio G
* Coordination Features Of Difunctionalized Beta-Cyclodextrins With Carnosine: Esi-Ms And Spectroscopic Investigations On 6a, 6d-Di-(beta-Alanyl-L-Histidine)-6a, 6d-Dideoxy-Beta-Cyclodextrin And 6a, 6c-Di-(beta-Alanyl-L-Histidine)-6a, 6c-Dideoxy-Beta-Cyclodextrin And Their Copper (ii) Complexes (149 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2004 Feb; 98(2): 254-265.
Impact Factor: 2.225
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Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (178 visite)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
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Bonomo RP, Bruno V, Conte E, De Guidi G, La Mendola D, Maccarrone G, Nicoletti F, Rizzarelli E, Sortino S, Vecchio G
* Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (176 visite)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2003; (23): 4406-4415.
Impact Factor: 2.908
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Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (157 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
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Mineo P, Vitalini D, La Mendola D, Rizzarelli E, Scamporrino E, Vecchio G
* Electrospray mass spectrometric studies of L-carnosine (β-alanyl-L-histidine) complexes with copper(II) or zinc ions in aqueous solution (161 visite)
Rapid Commun Mass Sp (ISSN: 0951-4198, 1097-0231electronic, 0951-4198linking), 2002; 16(7): 722-729.
Impact Factor: 2.372
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La Mendola D, Sortino S, Rizzarelli E, Vecchiog
* Synthesis Of New Carnosine Derivatives Of R-Cyclodextrin And Their Hydroxyl Radical Scavanger Ability (130 visite)
Helvetica Chimica Acta, 2002; 85: 1633-1643.
Impact Factor: 1.394
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Vecchio G, La Mendola D, Rizzarelli E, Sortino S
* SOD-like activity of copper(II) complexes of beta-cyclodextrins functionalized with carnosine (139 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2001 Sep; 86(1): N/D-N/D.
Impact Factor: 1.729
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Tabbì G, Nauser T, Koppenol WH, Reedijk J
A Pulse Radiolysis Study of an Imidazolato-Bridged Asymmetric Dicopper(II) Complex: A Structural and Functional Mimic of Superoxide Dismutase (130 visite)
Eur J Inorg Chem (ISSN: 1434-1948, 1099-0682e), 1998; (12): 1939-1943.
Impact Factor: 2.222
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45 Records (42 escludendo Abstract e Conferenze).
Impact factor totale: 167.327 (157.292 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 176.787 (164.54 escludendo Abstract e Conferenze).

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