Understanding the binding properties of an unusual metal-binding protein - a study of bacterial frataxin (113 visite)
Febs Journal (ISSN: 1742-464x), 2007 Sep; 274(16): 4199-4210.
Tipo di articolo: Journal Article,
Impact factor: 3.396, Impact factor a 5 anni: 3.405
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-34547760795&partnerID=40&md5=ed6de646c31d2fcc2ea552d1db8b15c0
Parole chiave: Cyay, Friedreich, S Ataxia, Iron Binding, X-Ray, Aspartic Acid, Cation, Cyay Protein, Cysteine, Frataxin, Glutamic Acid, Histidine, Iron Binding Protein, Metal, Unclassified Drug, Binding Affinity, Binding Site, Electricity, Iron Chelation, Metal Binding, Nuclear Magnetic Resonance, Orthology, Priority Journal, Protein Binding, Protein Function, X Ray Crystallography, Amino Acid Sequence, Bacterial Proteins, Competitive, Cobalt, Gadolinium, Iron-Binding Proteins, Iron-Sulfur Proteins, Lanthanoid Series Elements, Lutetium, Magnesium, Magnetic Resonance Spectroscopy, Molecular Sequence Data, Mutation, Protein Conformation, Protein Structure, Tertiary, Sequence Homology, Zinc, Bacteria (microorganisms),
Affiliazioni:
*** IBB - CNR ***
NIMR, The Ridgeway, London, NW71AA, United Kingdom
National Institute for Medical Research, London, United Kingdom
Dipartimento di Chimica, University of Naples, Italy
Istituto di Biostrutture e Bioimmagini, CNR, Naples, Italy
Riferimenti:
Campuzano, V., Montermini, L., Molto, M.D., Pianese, L., Cossée, M., Cavalcanti, F., Monros, E., Monticelli, A., Friedreich's ataxia: Autosomal recessive disease caused by an intronic GAA triplet repeat expansion (1996) Science, 271, pp. 1423-142
Cossee, M., Puccio, H., Gansmuller, A., Koutnikova, H., Dierich, A., Lemeur, M., Fischbeck, K., Koenig, M., Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (2000) Hum Mol Genet, 9, pp. 1219-1226
Yoon, T., Cowan, J.A., Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins (2003) J Am Chem Soc, 125, pp. 6078-6084
Bulteau, A.L., O'Neill, H.A., Kennedy, M.C., Ikeda-Saito, M., Isaya, G., Szweda, L.I., Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity (2004) Science, 305, pp. 242-245
Gerber, J., Muhlenhoff, U., Lill, R., An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1 (2003) EMBO Reports, 4, pp. 906-911
Park, S., Gakh, O., O'Neill, H.A., Mangravita, A., Nichol, H., Ferreira, G.C., Isaya, G., Yeast frataxin sequentially chaperones and stores iron by coupling protein assembly with iron oxidation (2003) J Biol Chem, 278, pp. 31340-31351
Cavadini, P., O'Neill, H.A., Benada, O., Isaya, G., Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich's ataxia (2002) Hum Mol Genet, 11, pp. 217-227
Delatycki, M.B., Williamson, R., Forrest, S.M., Freidreich's ataxia: An overview (2000) J Med Genet, 37, pp. 1-8
Huynen, M.A., Snel, B., Bork, P., Gibson, T.J., The phylogenetic distribution of frataxin indicates a role in iron-sulfur cluster protein assembly (2001) Hum Mol Genet, 10, pp. 2463-2468
Muhlenhoff, U., Richhardt, N., Ristow, M., Kispal, G., Lill, R., The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins (2002) Hum Mol Genet, 11, pp. 2025-2036
Stehling, O., Elsasser, H.-P., Bruckel, B., Muhlenhoff, U., Lill, R., Iron-sulfur protein maturation in human cells: Evidence for a function of frataxin (2004) Hum Mol Genet, 13, pp. 3007-3015
Wong, A., Yang, J., Cavadini, P., Gellera, C., Lonnerdal, B., Taroni, F., Cortopassi, G., The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis (1999) Hum Mol Genet, 8, pp. 425-430
Ristow, M., Pfister, M.F., Yee, A.J., Schubert, M., Michael, L., Zhang, C.-Y., Ueki, K., Kahn, C.R., Frataxin activates mitochondrial energy conversion and oxidative phosphorylation (2000) Proc Natl Acad Sci USA, 97, pp. 12239-12243
Tan, G., Napoli, E., Taroni, F., Cortopassi, G., Decreased expression of genes involved in sulfur amino acid metabolism in frataxin-deficient cells (2003) Hum Mol Genet, 12, pp. 1699-1711
Lesuisse, E., Santos, R., Matzanke, B.F., Knight, S.A.B., Camadro, J.-M., Dancis, A., Iron use for heme synthesis is under control of the yeast frataxin homologue (Yfh1) (2003) Hum Mol Genet, 12, pp. 879-889
Radisky, D.C., Babcock, M.C., Kaplan, J., The yeast frataxin homologue mediates mitochondrial iron efflux: Evidence for a mitochondrial iron cycle (1999) J Biol Chem, 274, pp. 4497-4499
Foury, F., Talibi, D., Mitochondrial control of iron homeostasis. a genome wide analysis of gene expression in a yeast frataxin-deficient strain (2001) J Biol Chem, 276, pp. 7762-7768
Que Jr., L., Ho, R.Y., Dioxygen activation by enzymes with mononuclear non-heme iron active sites (1996) Chem Rev, 96, pp. 2607-2624
Musco, G., Stier, G., Kolmerer, B., Adinolfi, S., Martin, S., Frenkiel, T., Gibson, T., Pastore, A., Towards a structural understanding of Friedreich's ataxia: The olution structure of frataxin (2000) Structure, 8, pp. 695-707
Dhe-Paganon, S., Shigeta, R., Chi, Y.-I., Ristow, M., Shoelson, S.E., Crystal structure of human frataxin (2000) J Biol Chem, 275, pp. 30753-30756
Cho, S.J., Lee, M.G., Yang, J.Y., Song, H.K., Suh, S.W., Crystal structure of Escherichia coli CyaY reveals a previously unidentified fold for the evolutionary conserved frataxin family (2000) Proc Natl Acad Sci USA, 97, pp. 8932-8937
Nair, M., Adinolfi, S., Pastore, C., Kelly, G., Temussi, P., Pastore, A., Solution structure of the bacterial frataxin ortholog, CyaY: Mapping the iron binding sites (2004) Structure (Camb), 12, pp. 2037-2048
He, Y., Alam, S.L., Proteasa, S.V., Zhang, Y., Lesuisse, E., Dancis, A., Stemmler, T.L., Yeast frataxin solution structure, iron binding and ferrochelatase interaction (2004) Biochemistry, 43, pp. 16254-16262
Bou-Abdallah, F., Adinolfi, S., Pastore, A., Laue, T.M., Chasteen, D.N., Iron binding and oxidation kinetics in frataxin CyaY of Escherichia coli (2004) J Mol Biol, 341, pp. 605-615
Adinolfi, S., Trifuoggi, M., Politou, A.S., Martin, S., Pastore, A., A structural approach to understanding the iron-binding properties of phylogenetically different frataxins (2002) Hum Mol Genet, 11, pp. 1865-1877
Adinolfi, S., Nair, M., Politou, A., Bayer, E., Martin, S., Temussi, P., Pastore, A., The factors governing the thermal stability of frataxin orthologues: How to increase a protein's stability (2004) Biochemistry, 43, pp. 6511-6518
Butchard, C.G., Dwek, R.A., Ferguson, S.J., Kent, P.W., Williams, R.J.P., Xavier, A.V., (1972) FEBS Lett, 25, pp. 91-93. , Mapping of the binding site of N-fluoroacetyl-d-glucosamine and analogues in hen egg lysozyme by 1H and 19F-NMR techniques with Gd(III) and Mn(II) as paramagnetic probes
Bertini, I., Luchinat, C., NMR of paramagnetic substances (1996) Coord Chem Rev, 150, p. 1
Saito, T., Wormald, M.R., Williams, R.J., Some structural features of the iron-uptake regulation protein (1991) Eur J Biochem, 197, pp. 29-38
Evans, C.H., (1990) Biochemistry of the Lanthanides., , Plenum Press, New York, NY
Carter Jr., C.W., Sweet, R.M., Macromolecular crystallography. Part a (1997) Methods Enzymol, 276, pp. 530-538
Karlberg, T., Schagerlof, U., Gakh, O., Park, S., Ryde, U., Lindahl, M., Leath, K., Al-Karadaghi, S., The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron (2006) Structure, 14, pp. 1535-1546
Foury, F., Pastore, A., Trincal, M., Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly (2007) EMBO Report, 8, pp. 194-199
Delaglio, F., Grzesiek, S., Vuister, G., Zhu, G., Pfeifer, J., Bax, A., NMRPipe: A multidimensional spectral processing system based on UNIX pipes (1995) J Biomol NMR, 6, pp. 277-293
Bartels, C., Xia, T.-H., Billeter, M., Güntert, P., Wüthrich, K., The program XEASY for computer-supported NMR spectral analysis of biological macromolecules (1995) J Biomol NMR, 5, pp. 1-10
Otwinowski, Z., Minor, W., Processing of X-ray diffraction data collected in oscillation mode (1997) Methods Enzymol, 276, pp. 307-326
Brünger, A.T., Adams, P.D., Clore, G.M., Delano, W.L., Gros, P., Grosse-Kunstleve, R.W., Jiang, J.-S., Pannu, N.S., Crystallography and NMR system: A new software suite for macromolecular structure determination (1998) Acta Crystallogr, 54, pp. 905-921
Schneider, T.R., Sheldrick, G.M., Substructure solution with SHELXD (2002) Acta Crystallogr D Biol Crystallogr, 58, pp. 1772-1779
The CCP4 suite: Programs for protein crystallography (1994) Acta Crystallogr D Biol Crystallogr, 50, pp. 760-763. , Collaborative Computational Project Number 4 (
Jones, T.A., Zou, J.Y., Cowan, S.W., Kjeldgaard, M., Improved methods for building protein models in electron density maps and the location of errors in these models (1991) Acta Crystallogr, 47, pp. 110-119
Laskowski, R.A., MacArthur, M.W., Moss, D.S., Thornton, J.M., PROCHECK: A program to check the stereochemical quality of protein structure (1993) J Appl Crystallogr, 26, pp. 283-291
Hooft, R.W., Vriend, G.S., Abola, E.E., Errors in protein structures (1996) Nature, 381, p. 272
Koradi, R., Billeter, M., Wüthrich, K., MOLMOL: A program for display and analysis of macromolecular structure (1996) J Mol Graph, 14, pp. 51-55
Esnouf, R.M., Further additions to Molscript, Version 1.4, including reading and contouring of electron-density maps (1999) Acta Crystallogr, 55, pp. 938-940
Yoon, T., Cowan, J. A., Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins (2003) J Am Chem Soc, 125, pp. 6078-6084
Bulteau, A. L., O'Neill, H. A., Kennedy, M. C., Ikeda-Saito, M., Isaya, G., Szweda, L. I., Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity (2004) Science, 305, pp. 242-245
Delatycki, M. B., Williamson, R., Forrest, S. M., Freidreich's ataxia: An overview (2000) J Med Genet, 37, pp. 1-8
Huynen, M. A., Snel, B., Bork, P., Gibson, T. J., The phylogenetic distribution of frataxin indicates a role in iron-sulfur cluster protein assembly (2001) Hum Mol Genet, 10, pp. 2463-2468
Radisky, D. C., Babcock, M. C., Kaplan, J., The yeast frataxin homologue mediates mitochondrial iron efflux: Evidence for a mitochondrial iron cycle (1999) J Biol Chem, 274, pp. 4497-4499
Que Jr., L., Ho, R. Y., Dioxygen activation by enzymes with mononuclear non-heme iron active sites (1996) Chem Rev, 96, pp. 2607-2624
Cho, S. J., Lee, M. G., Yang, J. Y., Song, H. K., Suh, S. W., Crystal structure of Escherichia coli CyaY reveals a previously unidentified fold for the evolutionary conserved frataxin family (2000) Proc Natl Acad Sci USA, 97, pp. 8932-8937
He, Y., Alam, S. L., Proteasa, S. V., Zhang, Y., Lesuisse, E., Dancis, A., Stemmler, T. L., Yeast frataxin solution structure, iron binding and ferrochelatase interaction (2004) Biochemistry, 43, pp. 16254-16262
Butchard, C. G., Dwek, R. A., Ferguson, S. J., Kent, P. W., Williams, R. J. P., Xavier, A. V., (1972) FEBS Lett, 25, pp. 91-93. , Mapping of the binding site of N-fluoroacetyl-d-glucosamine and analogues in hen egg lysozyme by 1H and 19F-NMR techniques with Gd (III) and Mn (II) as paramagnetic probes
Evans, C. H., (1990) Biochemistry of the Lanthanides., , Plenum Press, New York, NY
Carter Jr., C. W., Sweet, R. M., Macromolecular crystallography. Part a (1997) Methods Enzymol, 276, pp. 530-538
Br nger, A. T., Adams, P. D., Clore, G. M., Delano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. -S., Pannu, N. S., Crystallography and NMR system: A new software suite for macromolecular structure determination (1998) Acta Crystallogr, 54, pp. 905-921
Schneider, T. R., Sheldrick, G. M., Substructure solution with SHELXD (2002) Acta Crystallogr D Biol Crystallogr, 58, pp. 1772-1779
Jones, T. A., Zou, J. Y., Cowan, S. W., Kjeldgaard, M., Improved methods for building protein models in electron density maps and the location of errors in these models (1991) Acta Crystallogr, 47, pp. 110-119
Laskowski, R. A., MacArthur, M. W., Moss, D. S., Thornton, J. M., PROCHECK: A program to check the stereochemical quality of protein structure (1993) J Appl Crystallogr, 26, pp. 283-291
Hooft, R. W., Vriend, G. S., Abola, E. E., Errors in protein structures (1996) Nature, 381, p. 272
Esnouf, R. M., Further additions to Molscript, Version 1. 4, including reading and contouring of electron-density maps (1999) Acta Crystallogr, 55, pp. 938-940
Febs Journal (ISSN: 1742-464x), 2007 Sep; 274(16): 4199-4210.
Tipo di articolo: Journal Article,
Impact factor: 3.396, Impact factor a 5 anni: 3.405
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-34547760795&partnerID=40&md5=ed6de646c31d2fcc2ea552d1db8b15c0
Parole chiave: Cyay, Friedreich, S Ataxia, Iron Binding, X-Ray, Aspartic Acid, Cation, Cyay Protein, Cysteine, Frataxin, Glutamic Acid, Histidine, Iron Binding Protein, Metal, Unclassified Drug, Binding Affinity, Binding Site, Electricity, Iron Chelation, Metal Binding, Nuclear Magnetic Resonance, Orthology, Priority Journal, Protein Binding, Protein Function, X Ray Crystallography, Amino Acid Sequence, Bacterial Proteins, Competitive, Cobalt, Gadolinium, Iron-Binding Proteins, Iron-Sulfur Proteins, Lanthanoid Series Elements, Lutetium, Magnesium, Magnetic Resonance Spectroscopy, Molecular Sequence Data, Mutation, Protein Conformation, Protein Structure, Tertiary, Sequence Homology, Zinc, Bacteria (microorganisms),
Affiliazioni:
*** IBB - CNR ***
NIMR, The Ridgeway, London, NW71AA, United Kingdom
National Institute for Medical Research, London, United Kingdom
Dipartimento di Chimica, University of Naples, Italy
Istituto di Biostrutture e Bioimmagini, CNR, Naples, Italy
Riferimenti:
Campuzano, V., Montermini, L., Molto, M.D., Pianese, L., Cossée, M., Cavalcanti, F., Monros, E., Monticelli, A., Friedreich's ataxia: Autosomal recessive disease caused by an intronic GAA triplet repeat expansion (1996) Science, 271, pp. 1423-142
Cossee, M., Puccio, H., Gansmuller, A., Koutnikova, H., Dierich, A., Lemeur, M., Fischbeck, K., Koenig, M., Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (2000) Hum Mol Genet, 9, pp. 1219-1226
Yoon, T., Cowan, J.A., Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins (2003) J Am Chem Soc, 125, pp. 6078-6084
Bulteau, A.L., O'Neill, H.A., Kennedy, M.C., Ikeda-Saito, M., Isaya, G., Szweda, L.I., Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity (2004) Science, 305, pp. 242-245
Gerber, J., Muhlenhoff, U., Lill, R., An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1 (2003) EMBO Reports, 4, pp. 906-911
Park, S., Gakh, O., O'Neill, H.A., Mangravita, A., Nichol, H., Ferreira, G.C., Isaya, G., Yeast frataxin sequentially chaperones and stores iron by coupling protein assembly with iron oxidation (2003) J Biol Chem, 278, pp. 31340-31351
Cavadini, P., O'Neill, H.A., Benada, O., Isaya, G., Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich's ataxia (2002) Hum Mol Genet, 11, pp. 217-227
Delatycki, M.B., Williamson, R., Forrest, S.M., Freidreich's ataxia: An overview (2000) J Med Genet, 37, pp. 1-8
Huynen, M.A., Snel, B., Bork, P., Gibson, T.J., The phylogenetic distribution of frataxin indicates a role in iron-sulfur cluster protein assembly (2001) Hum Mol Genet, 10, pp. 2463-2468
Muhlenhoff, U., Richhardt, N., Ristow, M., Kispal, G., Lill, R., The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins (2002) Hum Mol Genet, 11, pp. 2025-2036
Stehling, O., Elsasser, H.-P., Bruckel, B., Muhlenhoff, U., Lill, R., Iron-sulfur protein maturation in human cells: Evidence for a function of frataxin (2004) Hum Mol Genet, 13, pp. 3007-3015
Wong, A., Yang, J., Cavadini, P., Gellera, C., Lonnerdal, B., Taroni, F., Cortopassi, G., The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis (1999) Hum Mol Genet, 8, pp. 425-430
Ristow, M., Pfister, M.F., Yee, A.J., Schubert, M., Michael, L., Zhang, C.-Y., Ueki, K., Kahn, C.R., Frataxin activates mitochondrial energy conversion and oxidative phosphorylation (2000) Proc Natl Acad Sci USA, 97, pp. 12239-12243
Tan, G., Napoli, E., Taroni, F., Cortopassi, G., Decreased expression of genes involved in sulfur amino acid metabolism in frataxin-deficient cells (2003) Hum Mol Genet, 12, pp. 1699-1711
Lesuisse, E., Santos, R., Matzanke, B.F., Knight, S.A.B., Camadro, J.-M., Dancis, A., Iron use for heme synthesis is under control of the yeast frataxin homologue (Yfh1) (2003) Hum Mol Genet, 12, pp. 879-889
Radisky, D.C., Babcock, M.C., Kaplan, J., The yeast frataxin homologue mediates mitochondrial iron efflux: Evidence for a mitochondrial iron cycle (1999) J Biol Chem, 274, pp. 4497-4499
Foury, F., Talibi, D., Mitochondrial control of iron homeostasis. a genome wide analysis of gene expression in a yeast frataxin-deficient strain (2001) J Biol Chem, 276, pp. 7762-7768
Que Jr., L., Ho, R.Y., Dioxygen activation by enzymes with mononuclear non-heme iron active sites (1996) Chem Rev, 96, pp. 2607-2624
Musco, G., Stier, G., Kolmerer, B., Adinolfi, S., Martin, S., Frenkiel, T., Gibson, T., Pastore, A., Towards a structural understanding of Friedreich's ataxia: The olution structure of frataxin (2000) Structure, 8, pp. 695-707
Dhe-Paganon, S., Shigeta, R., Chi, Y.-I., Ristow, M., Shoelson, S.E., Crystal structure of human frataxin (2000) J Biol Chem, 275, pp. 30753-30756
Cho, S.J., Lee, M.G., Yang, J.Y., Song, H.K., Suh, S.W., Crystal structure of Escherichia coli CyaY reveals a previously unidentified fold for the evolutionary conserved frataxin family (2000) Proc Natl Acad Sci USA, 97, pp. 8932-8937
Nair, M., Adinolfi, S., Pastore, C., Kelly, G., Temussi, P., Pastore, A., Solution structure of the bacterial frataxin ortholog, CyaY: Mapping the iron binding sites (2004) Structure (Camb), 12, pp. 2037-2048
He, Y., Alam, S.L., Proteasa, S.V., Zhang, Y., Lesuisse, E., Dancis, A., Stemmler, T.L., Yeast frataxin solution structure, iron binding and ferrochelatase interaction (2004) Biochemistry, 43, pp. 16254-16262
Bou-Abdallah, F., Adinolfi, S., Pastore, A., Laue, T.M., Chasteen, D.N., Iron binding and oxidation kinetics in frataxin CyaY of Escherichia coli (2004) J Mol Biol, 341, pp. 605-615
Adinolfi, S., Trifuoggi, M., Politou, A.S., Martin, S., Pastore, A., A structural approach to understanding the iron-binding properties of phylogenetically different frataxins (2002) Hum Mol Genet, 11, pp. 1865-1877
Adinolfi, S., Nair, M., Politou, A., Bayer, E., Martin, S., Temussi, P., Pastore, A., The factors governing the thermal stability of frataxin orthologues: How to increase a protein's stability (2004) Biochemistry, 43, pp. 6511-6518
Butchard, C.G., Dwek, R.A., Ferguson, S.J., Kent, P.W., Williams, R.J.P., Xavier, A.V., (1972) FEBS Lett, 25, pp. 91-93. , Mapping of the binding site of N-fluoroacetyl-d-glucosamine and analogues in hen egg lysozyme by 1H and 19F-NMR techniques with Gd(III) and Mn(II) as paramagnetic probes
Bertini, I., Luchinat, C., NMR of paramagnetic substances (1996) Coord Chem Rev, 150, p. 1
Saito, T., Wormald, M.R., Williams, R.J., Some structural features of the iron-uptake regulation protein (1991) Eur J Biochem, 197, pp. 29-38
Evans, C.H., (1990) Biochemistry of the Lanthanides., , Plenum Press, New York, NY
Carter Jr., C.W., Sweet, R.M., Macromolecular crystallography. Part a (1997) Methods Enzymol, 276, pp. 530-538
Karlberg, T., Schagerlof, U., Gakh, O., Park, S., Ryde, U., Lindahl, M., Leath, K., Al-Karadaghi, S., The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron (2006) Structure, 14, pp. 1535-1546
Foury, F., Pastore, A., Trincal, M., Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly (2007) EMBO Report, 8, pp. 194-199
Delaglio, F., Grzesiek, S., Vuister, G., Zhu, G., Pfeifer, J., Bax, A., NMRPipe: A multidimensional spectral processing system based on UNIX pipes (1995) J Biomol NMR, 6, pp. 277-293
Bartels, C., Xia, T.-H., Billeter, M., Güntert, P., Wüthrich, K., The program XEASY for computer-supported NMR spectral analysis of biological macromolecules (1995) J Biomol NMR, 5, pp. 1-10
Otwinowski, Z., Minor, W., Processing of X-ray diffraction data collected in oscillation mode (1997) Methods Enzymol, 276, pp. 307-326
Brünger, A.T., Adams, P.D., Clore, G.M., Delano, W.L., Gros, P., Grosse-Kunstleve, R.W., Jiang, J.-S., Pannu, N.S., Crystallography and NMR system: A new software suite for macromolecular structure determination (1998) Acta Crystallogr, 54, pp. 905-921
Schneider, T.R., Sheldrick, G.M., Substructure solution with SHELXD (2002) Acta Crystallogr D Biol Crystallogr, 58, pp. 1772-1779
The CCP4 suite: Programs for protein crystallography (1994) Acta Crystallogr D Biol Crystallogr, 50, pp. 760-763. , Collaborative Computational Project Number 4 (
Jones, T.A., Zou, J.Y., Cowan, S.W., Kjeldgaard, M., Improved methods for building protein models in electron density maps and the location of errors in these models (1991) Acta Crystallogr, 47, pp. 110-119
Laskowski, R.A., MacArthur, M.W., Moss, D.S., Thornton, J.M., PROCHECK: A program to check the stereochemical quality of protein structure (1993) J Appl Crystallogr, 26, pp. 283-291
Hooft, R.W., Vriend, G.S., Abola, E.E., Errors in protein structures (1996) Nature, 381, p. 272
Koradi, R., Billeter, M., Wüthrich, K., MOLMOL: A program for display and analysis of macromolecular structure (1996) J Mol Graph, 14, pp. 51-55
Esnouf, R.M., Further additions to Molscript, Version 1.4, including reading and contouring of electron-density maps (1999) Acta Crystallogr, 55, pp. 938-940
Yoon, T., Cowan, J. A., Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins (2003) J Am Chem Soc, 125, pp. 6078-6084
Bulteau, A. L., O'Neill, H. A., Kennedy, M. C., Ikeda-Saito, M., Isaya, G., Szweda, L. I., Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity (2004) Science, 305, pp. 242-245
Delatycki, M. B., Williamson, R., Forrest, S. M., Freidreich's ataxia: An overview (2000) J Med Genet, 37, pp. 1-8
Huynen, M. A., Snel, B., Bork, P., Gibson, T. J., The phylogenetic distribution of frataxin indicates a role in iron-sulfur cluster protein assembly (2001) Hum Mol Genet, 10, pp. 2463-2468
Radisky, D. C., Babcock, M. C., Kaplan, J., The yeast frataxin homologue mediates mitochondrial iron efflux: Evidence for a mitochondrial iron cycle (1999) J Biol Chem, 274, pp. 4497-4499
Que Jr., L., Ho, R. Y., Dioxygen activation by enzymes with mononuclear non-heme iron active sites (1996) Chem Rev, 96, pp. 2607-2624
Cho, S. J., Lee, M. G., Yang, J. Y., Song, H. K., Suh, S. W., Crystal structure of Escherichia coli CyaY reveals a previously unidentified fold for the evolutionary conserved frataxin family (2000) Proc Natl Acad Sci USA, 97, pp. 8932-8937
He, Y., Alam, S. L., Proteasa, S. V., Zhang, Y., Lesuisse, E., Dancis, A., Stemmler, T. L., Yeast frataxin solution structure, iron binding and ferrochelatase interaction (2004) Biochemistry, 43, pp. 16254-16262
Butchard, C. G., Dwek, R. A., Ferguson, S. J., Kent, P. W., Williams, R. J. P., Xavier, A. V., (1972) FEBS Lett, 25, pp. 91-93. , Mapping of the binding site of N-fluoroacetyl-d-glucosamine and analogues in hen egg lysozyme by 1H and 19F-NMR techniques with Gd (III) and Mn (II) as paramagnetic probes
Evans, C. H., (1990) Biochemistry of the Lanthanides., , Plenum Press, New York, NY
Carter Jr., C. W., Sweet, R. M., Macromolecular crystallography. Part a (1997) Methods Enzymol, 276, pp. 530-538
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Deficiency of the small mitochondrial protein frataxin causes Friedreich's ataxia, a severe neurodegenerative pathology. Frataxin, which has been highly conserved throughout evolution, is thought to be involved in, among other processes, Fe-S cluster formation. Independent evidence shows that it binds iron directly, although with very distinct features and low affinity. Here, we have carried out an extensive study of the binding properties of CyaY, the bacterial ortholog of frataxin, to different divalent and trivalent cations, using NMR and X-ray crystallography. We demonstrate that the protein has low cation specificity and contains multiple binding sites able to chelate divalent and trivalent metals with low affinity. Binding does not involve cavities or pockets, but exposed glutamates and aspartates, which are residues that are unusual for iron chelation when not assisted by histidines and/or cysteines. We have related how such an ability to bind cations on a relatively large area through an electrostatic mechanism could be a valuable asset for protein function.
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Maievskyi O, Samborska I, Kovalchuk O, Fagoonee S, Falalyeyeva T
* The Role of Hyperhomocysteinemia on the Development of Changes in the Lungs (0 visite)
Rev Recent Clin Trials (ISSN: 1574-8871linking), 2019 Nov 14; N/D: N/D-N/D.
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De Michele G, Lieto M, Galatolo D, Salvatore E, Cocozza S, Barghigiani M, Tessa A, Baldacci J, Pappata S, Filla A, De Michele G, Santorelli FM
* Spinocerebellar ataxia 48 presenting with ataxia associated with cognitive, psychiatric, and extrapyramidal features: A report of two Italian families (60 visite)
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Cocozza S, Costabile T, Tedeschi E, Abate F, Russo C, Liguori A, Del Vecchio W, Paciello F, Quarantelli M, Filla A, Brunetti A, Saccà F
* Cognitive and functional connectivity alterations in Friedreich's ataxia (140 visite)
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Impact Factor: 4.649
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Di Menna L, Joffe ME, Iacovelli L, Orlando R, Lindsley CW, Mairesse J, Gressèns P, Cannella M, Caraci F, Copani A, Bruno V, Battaglia G, Conn PJ, Nicoletti F
* Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system (178 visite)
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Impact Factor: 3.383
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Caraci F, Nicoletti F, Copani A
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Impact Factor: 6.313
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Depalo N, Corricelli M, De Paola I, Valente G, Iacobazzi RM, Altamura E, Debellis D, Comegna D, Fanizza E, Denora N, Laquintana V, Mavelli F, Striccoli M, Saviano M, Agostiano A, Del Gatto A, Zaccaro L, Curri ML
* NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging (140 visite) (PDF 95 visite)
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Monti DM, De Simone G, Langella E, Supuran CT, Di Fiore A, Monti SM
* Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage (162 visite)
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2017 Dec; 32(1): 5-12.
Impact Factor: 3.638
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Troise AD, Buonanno M, Fiore A, Monti SM, Fogliano V
* Evolution of protein bound Maillard reaction end-products and free Amadori compounds in low lactose milk in presence of fructosamine oxidase (131 visite)
Food Chem (ISSN: 0308-8146, 0308-8146print), 2016 Dec 1; 212: 722-729.
Impact Factor: 4.529
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Calce E, De Luca S
* The Cysteine S-Alkylation Reaction as a Synthetic Method to Covalently Modify Peptide Sequences (195 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Aug 19; 22: 1-11.
Impact Factor: 5.317
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D'Abrosca G, Russo L, Palmieri M, Baglivo I, Netti F, De Paola I, Zaccaro L, Farina B, Iacovino R, Pedone PV, Isernia C, Fattorusso R, Malgieri G
* The (unusual) aspartic acid in the metal coordination sphere of the prokaryotic zinc finger domain (132 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2016 Aug; 161: 91-98.
Impact Factor: 3.348
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Calce E, De Luca S
* Microwave heating in peptide side chain modification via cysteine alkylation (157 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2016 Jun 28; 48: 2267-2271.
Impact Factor: 3.173
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Troise AD, Fiore A, Roviello GN, Monti SM, Fogliano V
* Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry (240 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015 Jan; 47(1): 111-124.
Impact Factor: 3.196
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Cervo A, Cocozza S, Saccà F, Giorgio SM, Morra VB, Tedeschi E, Marsili A, Vacca G, Palma V, Brunetti A, Quarantelli M
* The combined use of conventional MRI and MR spectroscopic imaging increases the diagnostic accuracy in amyotrophic lateral sclerosis (178 visite)
Eur J Radiol (ISSN: 0720-048x), 2015 Jan; 84(1): 151-157.
Impact Factor: 2.593
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Calce E, Vitale RM, Scaloni A, Amodeo P, De Luca S
* Air oxidation method employed for the disulfide bond formation of natural and synthetic peptides (304 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015; 47(8): 1507-1515.
Impact Factor: 3.196
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Pica A, Graziano G
* On the effect of sodium chloride and sodium sulfate on cold denaturation (144 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2015; 10(7): N/D-N/D.
Impact Factor: 3.057
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Squeglia F, Ruggiero A, Romanò MF, Vitagliano L, Berisio R
* Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: Evidence for the l-to-d inversion of configuration of the catalytic cysteine (171 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2014 Sep; 70(9): 2295-2300.
Impact Factor: 14.1
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Merlino A, Russo Krauss I, Castellano I, Ruocco MR, Capasso A, De Vendittis E, Rossi B, Sica F
* Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability (192 visite)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014 Mar; 1844(3): 632-640.
Impact Factor: 4.882
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Caterino M, Merlino A, Balsamo A, Russo Krauss I, Parisi S, Vergara A
* Reaction of Hg2+ Insertion into Cysteine Pairs Within Bovine Insulin Crystals Followed via Raman Spectroscopy (159 visite)
J Solution Chem (ISSN: 0095-9782), 2014 Feb; 43(1): 135-143.
Impact Factor: 1.177
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D'Ambrosio K, Lopez M, Dathan NA, Ouahrani-bettache S, Köhler S, Ascione G, Monti SM, Winum JY, De Simone G
* Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis (195 visite)
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2014 Feb; 97(1): 114-120.
Impact Factor: 2.963
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Calce E, Sandomenico A, Saviano M, Ruvo M, De Luca S
* Cysteine Co-Oxidation Process Driven By Native Peptide Folding: An Example On Her2 Receptor Model System (165 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2014; 46(5): 1197-1206.
Impact Factor: 3.293
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Lin L-L, Chen Y-Y, Chi M-C, Merlino A
* Low resolution X-ray structure of γ-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion (167 visite)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014; 1844(9): 1523-1529.
Impact Factor: 4.882
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Sica F, Pica A, Merlino A, Russo Krauss I, Ercole C, Picone D
* The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer (155 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013 Nov 29; 587(23): 3755-3762.
Impact Factor: 3.341
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Del Giudice I, Limauro D, Pedone E, Bartolucci S, Fiorentino G
* A novel arsenate reductase from the bacterium Thermus thermophilus HB27: Its role in arsenic detoxification (204 visite)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Oct; 1834(10): 2071-2079.
Impact Factor: 3.191
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Portella L, Vitale R, De Luca S, D'Alterio C, Ieranò C, Napolitano M, Riccio A, Polimeno MN, Monfregola L, Barbieri A, Luciano A, Ciarmiello A, Arra C, Castello G, Amodeo P, Scala S
* Preclinical Development of a Novel Class of CXCR4 Antagonist Impairing Solid Tumors Growth and Metastases (229 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2013 Sep 13; 8(9): N/D-N/D.
Impact Factor: 3.534
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Dolga AM, Netter MF, Perocchi F, Doti N, Meissner L, Tobaben S, Grohm J, Zischka H, Plesnila N, Decher N, Culmsee C
* Mitochondrial Small Conductance SK2 Channels Prevent Glutamate-induced Oxytosis and Mitochondrial Dysfunction (229 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2013 Apr 12; 288(15): 10792-10804.
Impact Factor: 4.6
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Calce E, Leone M, Monfregola L, De Luca S
* Chemical Modifications Of Peptide Sequences Via S-Alkylation Reaction (149 visite)
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2013; 15(20): 5354-5357.
Impact Factor: 6.324
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Del Giudice R, Monti DM, Truppo E, Arciello A, Supuran CT, De Simone G, Monti SM
* Human Carbonic Anhydrase Vii Protects Cells From Oxidative Damage (156 visite)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1431-1673, 1437-4315), 2013; 394(10): 1343-1348.
Impact Factor: 2.689
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De Natale C, Minerva V, Patti L, Mazzarella R, Ciano O, Maione S, Luongo D, Naviglio D, Marotta G, Turco S, Ciati R, Melegari C, Rivellese AA, Riccardi G
* Effects Of Baked Products Enriched With N-3 Fatty Acids, Folates, β -Glucans, And Tocopherol In Patients With Mild Mixed Hyperlipidemia (144 visite)
J Am Coll Nutr (ISSN: 1541-1087, 0731-5724), 2012 Oct; 31(5): 311-319.
Impact Factor: 1.738
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Kaprelyants AS, Mukamolova GV, Ruggiero A, Makarov VA, Demina GR, Shleeva MO, Potapov VD, Shramko PA
* Resuscitation-promoting Factors (Rpf): In Search of Inhibitors (176 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1026-1034.
Impact Factor: 1.994
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Scarí G, Porta F, Fascio U, Avvakumova S, Dal Santo V, De Simone M, Saviano M, Leone M, Del Gatto A, Pedone C, Zaccaro L
* Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting (245 visite)
Bioconjug Chem (ISSN: 1520-4812, 1043-1802, 1520-4812electronic), 2012 Mar 21; 23(3): 340-349.
Impact Factor: 4.58
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Truppo E, Supuran CT, Sandomenico A, Vullo D, Innocenti A, Di Fiore A, Alterio V, De Simone G, Monti SM
* Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors (185 visite)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2012 Feb 15; 22(4): 1560-1564.
Impact Factor: 2.338
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Esposito L, Ruggiero A, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A, Vitagliano L
* Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability (159 visite)
J Struct Biol (ISSN: 1047-8477), 2012 Feb; 177(2): 506-512.
Impact Factor: 3.361
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Saccà F, Quarantelli M, Rinaldi C, Tucci T, Piro R, Perrotta G, Carotenuto B, Marsili A, Palma V, De Michele G, Brunetti A, Brescia Morra V, Filla A, Salvatore M
* A randomized controlled clinical trial of growth hormone in amyotrophic lateral sclerosis: clinical, neuroimaging, and hormonal results (237 visite)
J Neurol (ISSN: 1432-1459, 0340-5354, 1432-1459electronic), 2012 Jan; 259(1): 132-138.
Impact Factor: 3.578
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Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (200 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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Zaccaro L, Garcia-lopez Mt Gonzalez-muniz RG
* TRPV1 modulators: Structure-activity relationships using a rational combinatorial approach (178 visite)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2011 Jun 15; 21(12): 3541-3545.
Impact Factor: 2.554
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Riccio A, Mangiapia G, Giordano D, Flagiello A, Tedesco R, Bruno S, Vergara A, Mazzarella L, di Prisco G, Pucci P, Paduano L, Verde C
* Polymerization of Hemoglobins in Arctic Fish: Lycodes reticulatus and Gadus morhua (157 visite)
Iubmb Life (ISSN: 1521-6543, 1521-6551), 2011 May; 63(5): 346-354.
Impact Factor: 3.514
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Cirillo G, Bianco MR, Colangelo AM, Cavaliere C, Daniele DL, Zaccaro L, Alberghina L, Papa M
* Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor (198 visite)
Neurobiology Of Disease (ISSN: 0969-9961), 2011 Mar; 41(3): 630-639.
Impact Factor: 5.403
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Grasso G, Pietropaolo A, Spoto G, Pappalardo G, Tundo GR, Ciaccio C, Coletta M, Rizzarelli E
* Copper(I) and Copper(II) Inhibit A beta Peptides Proteolysis by Insulin-Degrading Enzyme Differently: Implications for Metallostasis Alteration in Alzheimer's Disease (261 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Feb 25; 17(9): 2752-2762.
Impact Factor: 5.925
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Santulli G, Basilicata MF, De Simone M, Del Giudice C, Anastasio A, Sorriento D, Saviano M, Del Gatto A, Trimarco B, Pedone C, Zaccaro L, Iaccarino G
* Evaluation of the anti-angiogenic properties of the new selective alphaVbeta3 integrin antagonist RGDechiHCit (257 visite)
J Transl Med Journal Of Translational Medicine (ISSN: 1479-5876electronic), 2011 Jan 13; 9: 7-7.
Impact Factor: 3.474
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Barile E, Leone M, Barile E, Dahl R, Pellecchia M
* Design and NMR Studies of Cyclic Peptides Targeting the N-Terminal Domain of the Protein Tyrosine Phosphatase YopH (256 visite)
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2011 Jan; 77(1): 12-19.
Impact Factor: 2.282
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Verardi R, Traaseth NJ, Shi L, Porcelli F, Monfregola L, De Luca S, Amodeo P, Veglia G, Scaloni A
* Probing membrane topology of the antimicrobial peptide distinctin by solid-state NMR spectroscopy in zwitterionic and charged lipid bilayers (224 visite)
Bba-Gen Subjects (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Jan; 1808(1): 34-40.
Impact Factor: 3.99
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Vergara A, Vitagliano L, Merlino A, Sica F, Marino K, Verde C, di Prisco G, Mazzarella L
* An Order-Disorder Transition Plays a Role in Switching Off the Root Effect in Fish Hemoglobins (172 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Oct 15; 285(42): 32568-32575.
Impact Factor: 5.328
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Guarnieri D, De Capua A, Ventre M, Borzacchiello A, Pedone C, Marasco D, Ruvo M, Netti PA
* Covalently immobilized RGD gradient on PEG hydrogel scaffold influences cell migration parameters (211 visite)
Acta Biomaterialia (ISSN: 1878-7568, 1742-7061), 2010 Jul; 6(7): 2532-2539.
Impact Factor: 4.824
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Tosco A, Monti MC, Fontanella B, Montefusco S, D'Andrea LD, Ziaco B, Baldantoni D, Rio MC, Marzullo L
* Copper binds the carboxy-terminus of trefoil protein 1 (TFF1), favoring its homodimerization and motogenic activity (199 visite)
Cell Mol Life Sci (ISSN: 1420-9071electronic, 1420-682xlinking), 2010 Jun; 67(11): 1943-1955.
Impact Factor: 7.047
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Pensato S, Renda M, Leccia F, Saviano M, D'Andrea LD, Pedone C, Pedone PV, Romanelli A
* PNA zipper as a dimerization tool: development of a bZip mimic (215 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 May; 93(5): 434-441.
Impact Factor: 2.572
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Monfregola L, Saviano M, De Luca S
* Synthesis and Characterization of a Selective Alpha(v)Beta(3) Receptor Cyclic Peptide Antagonist Functionalized with a Chelating Group for Metal Labelling (157 visite)
Int J Pept Res Ther (ISSN: 1573-3149, 0929-5666), 2010 Mar; 16(1): 1-5.
Impact Factor: 1.034
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Satriano C, Messina GM, Marino C, Aiello I, Conte E, La Mendola D, Distefano DA, D'Alessandro F, Pappalardo G, Impellizzeri G
* Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films - Effects on fibroblast spreading (269 visite)
J Colloid Interface Sci (ISSN: 1095-7103electronic, 0021-9797linking), 2010 Jan 15; 341(2): 232-239.
Impact Factor: 3.068
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Faiella M, Andreozzi C, de Rosales RT, Pavone V, Maglio O, Nastri F, DeGrado WF, Lombardi A
* An artificial di-iron oxo-protein with phenol oxidase activity (137 visite)
Nat Chem Biol (ISSN: 1552-4450), 2009 Dec; 5(12): 882-884.
Impact Factor: 16.058
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Merlino A, Russo Krauss I, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F
* Toward an Antitumor Form of Bovine Pancreatic Ribonuclease: The Crystal Structure of Three Noncovalent Dimeric Mutants (189 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1029-1037.
Impact Factor: 2.605
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Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA
* Nitric oxide in cell survival: a janus molecule (164 visite)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2717-2739.
Impact Factor: 7.581
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Zannetti A, Del Vecchio S, Iommelli F, Del Gatto A, De Luca S, Zaccaro L, Papaccioli A, Sommella J, Panico M, Speranza A, Grieco P, Novellino E, Saviano M, Pedone C, Salvatore M
* Imaging of αvβ3 expression by a bifunctional chimeric RGD peptide not cross-reacting with α vβ5 (270 visite)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2009 Sep 15; 15(16): 5224-5233.
Impact Factor: 6.747
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D'Ambrosio K, Limauro D, Pedone E, Galdi I, Pedone C, Bartolucci S, De Simone G
* Insights into the catalytic mechanism of the Bcp family: functional and structural analysis of Bcp1 from Sulfolobus solfataricus (185 visite)
Proteins (ISSN: 1097-0134, 0887-3585, 1097-0134electronic), 2009 Sep; 76(4): 995-1006.
Impact Factor: 3.085
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Ruggiero I, Cantiello P, Lamberti A, Sorrentino A, Martucci NM, Ruggiero A, Arcone R, Vitagliano L, Arcari P, Masullo M
* Biochemical Characterisation Of The D60a Mutant Of The Elongation Factor 1 Alpha From The Archaeon Sulfolobus Solfataricus (139 visite)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2009 Jul; 91(7): 835-842.
Impact Factor: 3.897
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La Mendola D, Magrì A, Hansson O, Bonomo RP, Rizzarelli E
* Copper(II) complexes with peptide fragments encompassing the sequence 122-130 of human doppel protein (158 visite)
Journal Of Inorganic Biochemistry, 2009 May; 103(5): 758-765.
Impact Factor: 3.444
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Accardo A, Tesauro D, Morisco A, Mangiapia G, Vaccaro M, Gianolio E, Heenan RK, Paduano L, Morelli G
* Micelles obtained by aggregation of gemini surfactants containing the CCK8 peptide and a gadolinium complex (220 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257linking), 2009 May; 14(4): 587-599.
Impact Factor: 3.415
Dettagli Esporta in BibTeX Esporta in EndNote
Zaccaro L, Del Gatto A, Pedone C, Saviano M
* Peptides for tumour therapy and diagnosis: current status and future directions (276 visite)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2009 Mar; 16(7): 780-795.
Impact Factor: 4.708
Dettagli Esporta in BibTeX Esporta in EndNote
Calvanese L, Saporito A, Oliva R, D'Auria G, Pedone C, Paolillo L, Ruvo M, Marasco D, Falcigno L
* Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor (177 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 175-183.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
Merlino A, Avella G, Di Gaetano S, Arciello A, Piccoli R, Mazzarella L, Sica F
* Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant (163 visite)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic, 0961-8368linking), 2009 Jan; 18(1): 50-57.
Impact Factor: 2.937
Dettagli Esporta in BibTeX Esporta in EndNote
Limauro D, Saviano M, Galdi I, Rossi M, Bartolucci S, Pedone E
* Sulfolobus solfataricus protein disulphide oxidoreductase: insight into the roles of its redox sites (108 visite)
Protein Engineering Design & Selection (ISSN: 1741-0126), 2009 Jan; 22(1): 19-26.
Impact Factor: 2.596
Dettagli Esporta in BibTeX Esporta in EndNote
Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
* Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (332 visite)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2008 Dec; 33(12): 2444-2471.
Impact Factor: 2.26
Dettagli Esporta in BibTeX Esporta in EndNote
Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
* The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders (184 visite)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2008 Dec; 33(12): 2401-2406.
Impact Factor: 2.26
Dettagli Esporta in BibTeX Esporta in EndNote
Vitagliano L, Vergara A, Bonomi G, Merlino A, Verde C, Di Prisco G, Howes BD, Smulevich G, Mazzarella L
* Spectroscopic and crystallographic characterization of a tetrameric hemoglobin oxidation reveals structural features of the functional intermediate relaxed/tense state (181 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2008 Sep 13; 130(32): 10527-10535.
Impact Factor: 8.091
Dettagli Esporta in BibTeX Esporta in EndNote
Limauro D, Pedone E, Galdi I, Bartolucci S
* Peroxiredoxins as cellular guardians in Sulfolobus solfataricus - characterization of Bcp1, Bcp3 and Bcp4 (178 visite)
Febs Journal (ISSN: 1742-464x), 2008 May; 275(9): 2067-2077.
Impact Factor: 3.139
Dettagli Esporta in BibTeX Esporta in EndNote
Malgieri G, Russo L, Esposito S, Baglivo I, Zaccaro L, Pedone EM, Di Blasio B, Isernia C, Pedone PV, Fattorusso R
* The Prokaryotic Cys2his2 Zinc Finger Domain Adopts A Novel Fold As Revealed By The Solution Structure Of Agrobacterium Tumefaciens Ros Dna Binding Domain (175 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2007 Oct 30; 104(44): 17341-17346.
Impact Factor: 9.598
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Varrone A, Pagani M, Salvatore E, Salmaso D, Sansone V, Amboni M, Nobili F, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Identification by [Tc-99]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease (210 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Jul; 34(7): 1071-1081.
Impact Factor: 4.101
Dettagli Esporta in BibTeX Esporta in EndNote
Agostini S, Bolzati C, Didonè E, Cavazza-Ceccato M, Refosco F, Aloj L, Arra C, Aurilio M, Tornesello AL, Tesauro D, Morelli G
* The (Tc(N)(PNP))2+ metal fragment labeled cholecystokinin-8 (CCK8) peptide for CCK-2 receptors imaging: In vitro and in vivo studies (205 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2007 Apr; 13(4): 211-219.
Impact Factor: 1.768
Dettagli Esporta in BibTeX Esporta in EndNote
Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Messina M, Vecchio G
* High selectivity in new chiral separations of dansyl amino acids by cyclodextrin derivatives in electrokinetic chromatography (160 visite)
J Chromatogr A (ISSN: 0021-9673), 2007; 1155(2): 172-179.
Impact Factor: 3.641
Dettagli Esporta in BibTeX Esporta in EndNote
Pailot A, D'Ambrosio K, Corbier C, Talfournier F, Branlant G
* Invariant Thr(244) is essential for the efficient acylation step of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans (145 visite)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2006 Dec 15; 400: 521-530.
Impact Factor: 4.1
Dettagli Esporta in BibTeX Esporta in EndNote
Saporito A, Marasco D, Chambery A, Botti P, Monti SM, Pedone C, Ruvo M
* The chemical synthesis of the GstI protein by NCL on a X-Met site (235 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2006 Dec 5; 83(5): 508-518.
Impact Factor: 2.48
Dettagli Esporta in BibTeX Esporta in EndNote
Pedone E, Limauro D, D'Alterio R, Rossi M, Bartolucci S
* Characterization of a multifunctional protein disulfide oxidoreductase from Sulfolobus solfataricus (118 visite)
Febs Journal (ISSN: 1742-464x), 2006 Dec; 273(23): 5407-5420.
Impact Factor: 3.033
Dettagli Esporta in BibTeX Esporta in EndNote
De Simone A, Berisio R, Zagari A, Vitagliano L
* Limited Tendency Of Alpha-Helical Residues To Form Disulfide Bridges: A Structural Explanation (234 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 740-747.
Impact Factor: 1.801
Dettagli Esporta in BibTeX Esporta in EndNote
Mazzarella L, Vergara A, Vitagliano L, Merlino A, Bonomi G, Scala S, Verde C, Di Prisco G
* High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect (154 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Nov 1; 65(2): 490-498.
Impact Factor: 3.73
Dettagli Esporta in BibTeX Esporta in EndNote
D'Ambrosio K, Pedone E, Langella E, De Simone G, Rossi M, Pedone C, Bartolucci S
* A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: Structure, function and electrostatics (140 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2006 Sep 29; 362(4): 743-752.
Impact Factor: 4.89
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito S, Baglivo I, Malgieri G, Russo L, Zaccaro L, D'Andrea LD, Mammucari M, Di Blasio B, Isernia C, Fattorusso R, Pedone PV
* A novel type of zinc finger DNA binding domain in the Agrobacterium tumefaciens transcriptional regulator Ros (179 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Sep 29; 45(34): 10394-10405.
Impact Factor: 3.633
Dettagli Esporta in BibTeX Esporta in EndNote
Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* A new spot test for sulfhydryl-containing compounds (200 visite)
Anal Biochem, 2006 Mar 14; 79(1-2): 610-611.
Impact Factor: 2.305
Dettagli Esporta in BibTeX Esporta in EndNote
Mazzarella L, Bonomi G, Lubrano MC, Merlino A, Riccio A, Vergara A, Vitagliano L, Verde C, Di Prisco G
* Minimal structural requirements for root effect: Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus newnesi (211 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Feb 1; 62(2): 316-321.
Impact Factor: 3.73
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De Capua A, Goodman M, Amino Y, Saviano M, Benedetti E
* Conformation analysis of aspartame-based sweeteners by NMR spectroscopy, molecular dynamics simulations, and X-ray diffraction studies (318 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2006 Feb; 7(2): 377-387.
Impact Factor: 4.1
Dettagli Esporta in BibTeX Esporta in EndNote
D'Andrea LD, Del Gatto A, Pedone C, Benedetti E
* Peptide-based molecules in angiogenesis (229 visite)
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2006 Feb; 67(2): 115-126.
Impact Factor: 2.507
Dettagli Esporta in BibTeX Esporta in EndNote
Herga S, Brutus A, Vitale RM, Miche H, Perrier J, Puigserver A, Scaloni A, Giardina T
* Site-directed mutagenesis and molecular modelling studies show the role of Asp82 and cysteines in rat acylase 1, a member of the M20 family (147 visite)
Biochem Biophys Res Commun (ISSN: 0006-291xprint, 0006-291xlinking), 2005 May 6; 330(2): 540-546.
Impact Factor: 3
Dettagli Esporta in BibTeX Esporta in EndNote
Merlino A, Mazzarella L, Carannante A, Di Fiore A, Di Donato A, Notomista E, Sica F
* The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase mutants (194 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 May 6; 280(18): 17953-17960.
Impact Factor: 5.854
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito G, Vitagliano L, Cevenini A, Amelio T, Zagari A, Salvatore F
* Unraveling the structural and functional features of an aldolase A mutant involved in the hemolytic anemia and severe rhabdomyolysis reported in a child (153 visite)
Haematologica (ISSN: 0006-4971, 0006-6497, 0390-6078), 2005 Jan 15; 105(2): 905-906.
Impact Factor: 10.131
Dettagli Esporta in BibTeX Esporta in EndNote
Sica F, Di Fiore A, Merlino A, Mazzarella L
* Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease - An enzyme tailored to evade ribonuclease protein inhibitor (147 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2004 Sep 27; 279(35): 36753-36760.
Impact Factor: 6.355
Dettagli Esporta in BibTeX Esporta in EndNote
Pedone E, Ren B, Ladenstein R, Rossi M, Bartolucci S
* Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus - A member of a novel protein family related to protein disulfide-isomerase (145 visite)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print), 2004 Sep; 271(16): 3437-3448.
Impact Factor: 3.26
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Panico M, Caraco C, Del Vecchio S, Arra C, Affuso A, Accardo A, Mansi R, Tesauro D, De Luca S, Pedone C, Visentin R, Mazzi U, Morelli G, Salvatore M
* In vitro and in vivo characterization of Indium-111 and Technetium-99m labeled CCK-8 derivatives for CCK-B receptor imaging (227 visite)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2004 Feb; 19(1): 93-98.
Impact Factor: 1.091
Dettagli Esporta in BibTeX Esporta in EndNote
Ohlenschlager O, Wohnert J, Bucci E, Seitz S, Hafner S, Ramachandran R, Zell R, Gorlach M
* The Structure of the Stemloop D Subdomain of Coxsackievirus B3 Cloverleaf RNA and Its Interaction with the Proteinase 3C (173 visite)
Structure (ISSN: 0969-2126, 1878-4186), 2004; 12(2): 237-248.
Impact Factor: 5.185
Dettagli Esporta in BibTeX Esporta in EndNote
Milardi D, Grasso DM, Verbeet MP, Canters GW, La Rosa C
* Thermodynamic analysis of the contributions of the copper ion and the disulfide bridge to azurin stability: Synergism among multiple depletions (177 visite)
Arch Biochem Biophys (ISSN: 0003-9861), 2003 Jun 1; 414(1): 121-127.
Impact Factor: 2.338
Dettagli Esporta in BibTeX Esporta in EndNote
Spalletti-cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M
* Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis (170 visite)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2003 Jun; 88(6): 2900-2907.
Impact Factor: 5.873
Dettagli Esporta in BibTeX Esporta in EndNote
Guzzi R, Milardi D, La Rosa C, Grasso D, Verbeet MP, Canters GW, Sportelli L
* The effect of copper/zinc replacement on the folding free energy of wild type and Cys3Ala/Cys26Ala azurin (144 visite)
Int J Biol Macromol (ISSN: 0141-8130, 0141-8130linking, 1879-0003electronic), 2003 Jan 15; 31(4-5): 163-170.
Impact Factor: 1.427
Dettagli Esporta in BibTeX Esporta in EndNote
Merlino A, Vitagliano L, Ceruso M, Di Nola A, Mazzarella L
* Global and local motions in ribonuclease A: A molecular dynamics study (190 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002 Nov 15; 65(4): 274-283.
Impact Factor: 2.372
Dettagli Esporta in BibTeX Esporta in EndNote
Dathan N, Zaccaro L, Esposito S, Isernia C, Omichinski JG, Riccio A, Pedone C, Di Blasio B, Fattorusso R, Pedone PV
* The Arabidopsis SUPERMAN protein is able to specifically bind DNA through its single Cys(2)-His(2) zinc finger motif (160 visite)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2002 Nov 15; 30(22): 4945-4951.
Impact Factor: 7.051
Dettagli Esporta in BibTeX Esporta in EndNote
Morelli G, De Luca S, Tesauro D, Saviano M, Pedone C, Dolmella A, Visentin R, Mazzi U
* CCK8 peptide derivatized with diphenylphosphine for rhenium labelling: Synthesis and molecular mechanics calculations (140 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2002 Jul; 8(7): 373-381.
Impact Factor: 1.691
Dettagli Esporta in BibTeX Esporta in EndNote
Zell R, Sidigi K, Bucci E, Stelzner A, Goerlach M
* Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C (178 visite)
Rna (ISSN: 1355-8382), 2002; 8(2): 188-201.
Impact Factor: 5.099
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Panico M, Caracó C, Zannetti A, Del Vecchio S, Di Nuzzo C, Arra C, Morelli G, Tesauro D, De Luca S, Pedone C, Salvatore M
* Radiolabeling approaches for cholecystokinin B receptor imaging (271 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002; 66(6): 370-380.
Impact Factor: 2.372
Dettagli Esporta in BibTeX Esporta in EndNote
De Simone G, Menchise V, Manco G, Mandrich L, Sorrentino N, Lang D, Rossi M, Pedone C
* The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus (159 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2001 Nov 30; 314(3): 507-518.
Impact Factor: 5.826
Dettagli Esporta in BibTeX Esporta in EndNote
Menchise V, Corbier C, Didierjean C, Saviano M, Benedetti E, Jacquot JP, Aubry A
* Crystal structure of the wild-type and D30A mutant thioredoxin h of Chlamydomonas reinhardtii and implications for the catalytic mechanism (176 visite)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2001 Oct 1; 359(1): 65-75.
Impact Factor: 4.326
Dettagli Esporta in BibTeX Esporta in EndNote
De Falco S, Ruvoletto MG, Verdoliva A, Ruvo M, Raucci A, Marino M, Senatore S, Cassani G, Alberti A, Pontisso P, Fassina G
* Cloning and Expression of a Novel Hepatitis B Virus-binding Protein from HepG2 Cells (215 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2001 Sep 28; 276(39): 36613-36623.
Impact Factor: 7.258
Dettagli Esporta in BibTeX Esporta in EndNote
Garzillo AM, Colao MC, Buonocore V, Oliva R, Falcigno L, Saviano M, Santoro AM, Zappala R, Bonomo RP, Bianco C, Giardina P, Palmieri G, Sannia G
* Structural and kinetic characterization of native laccases from Pleurotas ostreatus, Rigidoporus lignosus, and Trametes trogii (159 visite)
Journal Of Protein Chemistry (ISSN: 0277-8033), 2001 Apr; 20(3): 191-201.
Impact Factor: 1.021
Dettagli Esporta in BibTeX Esporta in EndNote
Lombardi A, Marasco D, Maglio O, Di Costanzo L, Nasti F, Pavone V
Miniaturized metalloproteins: Application to iron-sulfur proteins (406 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2000 Oct 24; 97(22): 11922-11927.
Impact Factor: 10.789
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito L, Vitagliano L, Sica F, Sorrentino G, Zagari A, Mazzarella L
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: Hydration and sterochemical analysis (213 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Mar 31; 297(3): 713-732.
Impact Factor: 5.388
Dettagli Esporta in BibTeX Esporta in EndNote
Martínez JC, Viguera AR, Berisio R, Wilmanns M, Mateo PL, Filimonov VV, Serrano L
Thermodynamic analysis of α-spectrin SH3 and two of its circular permutants with different loop lengths: Discerning the reasons for rapid folding in proteins (163 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 1999 Jan 12; 38(2): 549-559.
Impact Factor: 4.493
Dettagli Esporta in BibTeX Esporta in EndNote
De Michele G, Mainenti PP, Soricelli A, Di Salle F, Salvatore E, Longobardi MR, Postiglione A, Salvatore M, Filla A
Cerebral blood flow in spinocerebellar degenerations: a single photon emission tomography study in 28 patients (125 visite)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1998 Sep; 245(9): 603-608.
Impact Factor: 2.3
Dettagli Esporta in BibTeX Esporta in EndNote
Campagna T, Grasso G, Rizzarelli E, Vecchio G
L- and D-cysteine derivatives of β-cyclodextrin: Different molecular recognition properties of their copper(II) complexes for amino acids (151 visite)
Inorg Chim Acta (ISSN: 0020-1693), 1998; 275-276: 395-400.
Impact Factor: 1.454
Dettagli Esporta in BibTeX Esporta in EndNote
Capasso S, Di Donato A, Esposito L, Sica F, Sorrentino G, Vitagliano L, Zagari A, Mazzarella L
Deamidation in proteins: The crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67 (144 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1996; 257(3): 492-496.
Impact Factor: 5.673
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (193 visite)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
Dettagli Esporta in BibTeX Esporta in EndNote
Sijens PE, Knopp MV, Brunetti A, Wicklow K, Alfano B, Bachert P, Sanders JA, Stillman AE, Kett H, Sauter R
1H MR spectroscopy in patients with metastatic brain tumors: A multicenter study (134 visite)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic), 1995 Jun; 33(6): 818-826.
Impact Factor: 3.012
Dettagli Esporta in BibTeX Esporta in EndNote
Rossi F, Saviano M, Di Blasio B, Zanotti G, Maione AM, Tancredi T, Pedone C
BIOACTIVE PEPTIDES - SOLID-STATE, SOLUTION AND MOLECULAR-DYNAMICS STUDIES OF A CYCLOLINOPEPTIDE-A RELATED CYSTINYL CYCLOPENTAPEPTIDE (226 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1994 Feb; 34(2): 273-284.
Impact Factor: 2.425
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Miletich RS, Quarantelli M, Di Chiro G
REGIONAL CEREBRAL BLOOD-FLOW IMAGING WITH TC-99M-BICISATE SPECT IN ASYMMETRIC PARKINSONS-DISEASE - STUDIES WITH AND WITHOUT CHRONIC DRUG-THERAPY (159 visite)
Journal Of Cerebral Blood Flow And Metabolism (ISSN: 0271-678x), 1994 Jan; 14: S106-S106.
Impact Factor: 5.836
Dettagli Esporta in BibTeX Esporta in EndNote
107 Records (105 escludendo Abstract e Conferenze).
Impact factor totale: 441.042 (431.672 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 424.655 (415.313 escludendo Abstract e Conferenze).
Impact factor totale: 441.042 (431.672 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 424.655 (415.313 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
Ultima modifica di Marco Comerci in data Thursday 19 March 2015, 16:43:15
113 visite. Ultima visita in data Thursday 16 January 2020, 19:42:19
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