Development and characterization of an integrated silicon micro flow cytometer (328 views visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2006; 386(5): 1267-1272.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 2.591, 5-year impact factor Impact factor a 5 anni: 3.744
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-33750438125&partnerID=40&md5=0139c03a8cbc84e0556442067facf57a
Keywords Parole chiave: Biochips, High-Throughput Screening, Microfabrication, Microfluidics, Optical Sensors, Channel Flow, Fluorescence, Hydrodynamics, Optical Design, Optical Waveguides, Signal To Noise Ratio, High Throughput Screening, Flow Measurement, Silicon, Article, Chemistry, Comparative Study, Electrode, Equipment, Equipment Design, Fiber Optics, Flow Cytometry, Instrumentation, Sensitivity And Specificity, Temperature, Equipment Failure Analysis,
Affiliations Affiliazioni:
*** IBB - CNR ***
IREA-CNR, Via Diocleziano 328, 80124 Napoli, Italy
DII, Seconda Università di Napoli, Via Roma 29, 81031 Aversa, Italy
ECTM-DIMES, TUDelft, Feldmannweg 17, 2600 Delft, Netherlands
IBB-CNR, Via Mezzocannone 16, 80134 Napoli, Italy
References Riferimenti:
Huh, D., Ou, W., Kamotani, Y., Groteberg, J.B., Takayama, S., (2005) Physiol Meas, 26, pp. 73-9
Grunde, C., Skerlos, S., Adriaens, P., (2004) FEMS Micorbiol Ecol, 49, pp. 37-49
Tung, Y.C., Zhang, M., Lin, C.T., Kurabayashi, K., Skerlos, S.J., (2004) Sens Actuators B Chem, 98, pp. 356-367
Lin, C.H., Lee, G.B., (2003) J Micromech Microeng, 13, pp. 447-453
Kruger, J., Singh, K., O'Neill, A., Jackson, C., Morrison, A., O'Brien, P., (2002) J Micromech Microeng, 12, pp. 486-494
Wang, Z., El-Ali, J., Engelund, M., Gotsæd, T., Perch-Nielsen, I.R., Mogensen, Snakenborg, D., Wolff, A., (2004) Lab Chip, 4, pp. 372-377
Huh, D., Tung, Y.C., Wei, H.H., Grotberg, J.B., Skerlos, S.J., Kurabayashi, K., Takayama, S., (2002) Biomed Microdevices, 4, pp. 141-149
Chung, S., Park, S.J., Kim, J.K., Chung, C., Han, D.C., Chang, J.K., (2003) Microsyst Technol, 9, pp. 525-533
McClain, M.A., Culbertson, C.T., Jacobson, S.C., Ramsey, J.M., (2001) Anal Chem, 73, pp. 5334-5338
Holmes, D., Morgan, H., Green, N.G., (2006) Biosens Bioelectron, 21, pp. 1621-1630
Lee, G.-B., Lin, C.-H., Chang, G.-L., (2003) Sens Actuators a Phys, 103, pp. 165-170
Bernini, R., Campopiano, S., Zeni, L., (2002) IEEE J Selected Topics Quantum Elect, 8, p. 106
Tung, Y. C., Zhang, M., Lin, C. T., Kurabayashi, K., Skerlos, S. J., (2004) Sens Actuators B Chem, 98, pp. 356-367
Lin, C. H., Lee, G. B., (2003) J Micromech Microeng, 13, pp. 447-453
Huh, D., Tung, Y. C., Wei, H. H., Grotberg, J. B., Skerlos, S. J., Kurabayashi, K., Takayama, S., (2002) Biomed Microdevices, 4, pp. 141-149
Chung, S., Park, S. J., Kim, J. K., Chung, C., Han, D. C., Chang, J. K., (2003) Microsyst Technol, 9, pp. 525-533
McClain, M. A., Culbertson, C. T., Jacobson, S. C., Ramsey, J. M., (2001) Anal Chem, 73, pp. 5334-5338
Lee, G. -B., Lin, C. -H., Chang, G. -L., (2003) Sens Actuators a Phys, 103, pp. 165-170
Anal Bioanal Chem (ISSN: 1618-2642), 2006; 386(5): 1267-1272.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 2.591, 5-year impact factor Impact factor a 5 anni: 3.744
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-33750438125&partnerID=40&md5=0139c03a8cbc84e0556442067facf57a
Keywords Parole chiave: Biochips, High-Throughput Screening, Microfabrication, Microfluidics, Optical Sensors, Channel Flow, Fluorescence, Hydrodynamics, Optical Design, Optical Waveguides, Signal To Noise Ratio, High Throughput Screening, Flow Measurement, Silicon, Article, Chemistry, Comparative Study, Electrode, Equipment, Equipment Design, Fiber Optics, Flow Cytometry, Instrumentation, Sensitivity And Specificity, Temperature, Equipment Failure Analysis,
Affiliations Affiliazioni:
*** IBB - CNR ***
IREA-CNR, Via Diocleziano 328, 80124 Napoli, Italy
DII, Seconda Università di Napoli, Via Roma 29, 81031 Aversa, Italy
ECTM-DIMES, TUDelft, Feldmannweg 17, 2600 Delft, Netherlands
IBB-CNR, Via Mezzocannone 16, 80134 Napoli, Italy
References Riferimenti:
Huh, D., Ou, W., Kamotani, Y., Groteberg, J.B., Takayama, S., (2005) Physiol Meas, 26, pp. 73-9
Grunde, C., Skerlos, S., Adriaens, P., (2004) FEMS Micorbiol Ecol, 49, pp. 37-49
Tung, Y.C., Zhang, M., Lin, C.T., Kurabayashi, K., Skerlos, S.J., (2004) Sens Actuators B Chem, 98, pp. 356-367
Lin, C.H., Lee, G.B., (2003) J Micromech Microeng, 13, pp. 447-453
Kruger, J., Singh, K., O'Neill, A., Jackson, C., Morrison, A., O'Brien, P., (2002) J Micromech Microeng, 12, pp. 486-494
Wang, Z., El-Ali, J., Engelund, M., Gotsæd, T., Perch-Nielsen, I.R., Mogensen, Snakenborg, D., Wolff, A., (2004) Lab Chip, 4, pp. 372-377
Huh, D., Tung, Y.C., Wei, H.H., Grotberg, J.B., Skerlos, S.J., Kurabayashi, K., Takayama, S., (2002) Biomed Microdevices, 4, pp. 141-149
Chung, S., Park, S.J., Kim, J.K., Chung, C., Han, D.C., Chang, J.K., (2003) Microsyst Technol, 9, pp. 525-533
McClain, M.A., Culbertson, C.T., Jacobson, S.C., Ramsey, J.M., (2001) Anal Chem, 73, pp. 5334-5338
Holmes, D., Morgan, H., Green, N.G., (2006) Biosens Bioelectron, 21, pp. 1621-1630
Lee, G.-B., Lin, C.-H., Chang, G.-L., (2003) Sens Actuators a Phys, 103, pp. 165-170
Bernini, R., Campopiano, S., Zeni, L., (2002) IEEE J Selected Topics Quantum Elect, 8, p. 106
Tung, Y. C., Zhang, M., Lin, C. T., Kurabayashi, K., Skerlos, S. J., (2004) Sens Actuators B Chem, 98, pp. 356-367
Lin, C. H., Lee, G. B., (2003) J Micromech Microeng, 13, pp. 447-453
Huh, D., Tung, Y. C., Wei, H. H., Grotberg, J. B., Skerlos, S. J., Kurabayashi, K., Takayama, S., (2002) Biomed Microdevices, 4, pp. 141-149
Chung, S., Park, S. J., Kim, J. K., Chung, C., Han, D. C., Chang, J. K., (2003) Microsyst Technol, 9, pp. 525-533
McClain, M. A., Culbertson, C. T., Jacobson, S. C., Ramsey, J. M., (2001) Anal Chem, 73, pp. 5334-5338
Lee, G. -B., Lin, C. -H., Chang, G. -L., (2003) Sens Actuators a Phys, 103, pp. 165-170
Development and characterization of an integrated silicon micro flow cytometer
This paper describes an innovative integrated micro flow cytometer that presents a new arrangement for the excitation/detection system. The sample liquid, containing the fluorescent marked particles/cells under analysis, is hydrodynamically squeezed into a narrow stream by two sheath flows so that the particles/cells flow individually through a detection region. The detection of the particles/cells emitted fluorescence is carried out by using a collection fiber placed orthogonally to the flow. The device is based on silicon hollow core antiresonant reflecting optical waveguides (ARROWs). ARROW geometry allows one to use the same channel to guide both the sample stream and the fluorescence excitation light, leading to a simplification of the optical configuration and to an increase of the signal-to-noise ratio. The integrated micro flow cytometer has been characterized by using biological samples marked with standard fluorochromes. The experimental investigation confirms the success of the proposed microdevice in the detection of cells. © Springer-Verlag 2006.
This paper describes an innovative integrated micro flow cytometer that presents a new arrangement for the excitation/detection system. The sample liquid, containing the fluorescent marked particles/cells under analysis, is hydrodynamically squeezed into a narrow stream by two sheath flows so that the particles/cells flow individually through a detection region. The detection of the particles/cells emitted fluorescence is carried out by using a collection fiber placed orthogonally to the flow. The device is based on silicon hollow core antiresonant reflecting optical waveguides (ARROWs). ARROW geometry allows one to use the same channel to guide both the sample stream and the fluorescence excitation light, leading to a simplification of the optical configuration and to an increase of the signal-to-noise ratio. The integrated micro flow cytometer has been characterized by using biological samples marked with standard fluorochromes. The experimental investigation confirms the success of the proposed microdevice in the detection of cells. © Springer-Verlag 2006.
Development and characterization of an integrated silicon micro flow cytometer
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Development and characterization of an integrated silicon micro flow cytometer
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* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (439 visite)
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Doti N, Marasco D, Pedone C, Sabatella M, Ruvo M
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J Biomol Screen (ISSN: 1087-0571, 1552-454x, 1552-454xelectronic), 2009 Dec; 14(10): 1263-1268.
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Microchemical Journal (ISSN: 0026-265x), 2009 Sep; 93(1): 82-86.
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* Enzyme solid-state support assays: a surface plasmon resonance and mass spectrometry coupled study of immobilized insulin degrading enzyme (356 visite)
Eur Biophys J (ISSN: 1432-1017, 0175-7571), 2009 Apr; 38(4): 407-414.
Impact Factor: 2.437
Dettagli Esporta in BibTeX Esporta in EndNote
9 Records (8 escludendo Abstract e Conferenze).
Impact factor totale: 18.695 (18.695 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 18.723 (18.723 escludendo Abstract e Conferenze).
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328 views visite. Last view on Ultima visita in data Thursday 17 June 2021, 19:15:05
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