Inhibition of Sp1 activity by a decoy PNA-DNA chimera prevents urokinase receptor expression and migration of breast cancer cells (347 visite)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2005 Nov 1; 70(9): 1277-1287.
Tipo di articolo: Journal Article,
Impact factor: 3.617, Impact factor a 5 anni: 4.772
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-25644442324&partnerID=40&md5=ee6ad4844b2546aad2114f23c7770227
Parole chiave: Breast Cancer, Peptide Nucleic Acid, Pna-Dna Chimera, Sp1 Transcription Factor, Urokinase Receptor, Complementary Dna, Liposome, Oligonucleotide, Transcription Factor Sp1, Amino Acid Sequence, Article, Cancer Cell, Cancer Inhibition, Cell Migration, Cell Motility, Covalent Bond, Dna Strand, Down Regulation, Genetic Transfection, Human, Human Cell, In Vitro Study, Inhibition Kinetics, Metastasis, Priority Journal, Protein Binding, Protein Expression, Protein Function, Receptor Upregulation, Breast Neoplasms, Cell Line, Tumor, Cell Movement, Female, Cell Surface,
Affiliazioni:
*** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche, Via S. Pansini 5, 80131 Naples, Italy
Istituto di Endocrinologia Ed Oncologia Sperimentale, Consiglio Nazionale Delle Ricerche, Naples, Italy
Istituto Internazionale di Genetica e Biofisica, Consiglio Nazionale Delle Ricerche, Naples, Italy
Dipartimento di Scienze Biomorfologiche e Funzionali, Universita' Federico II, Naples, Italy
Riferimenti:
Chambers, A.F., Groom, A.C., MacDonald, I.C., Dissemination and growth of cancer cells in metastatic sites (2002) Nat Rev Cancer, 2, pp. 563-57
Andreasen, P.A., Egelund, R., Petersen, H.H., The plasminogen activation system in tumor growth, invasion, and metastasis (2000) Cell Mol Life Sci, 57, pp. 25-40
Blasi, F., Carmeliet, P., UPAR: A versatile signalling orchestrator (2002) Nat Rev Mol Cell Biol, 3, pp. 932-943
Ossowski, L., Aguirre-Ghiso, J.A., Urokinase receptor and integrin partnership: Coordination of signaling for cell adhesion, migration and growth (2000) Curr Opin Cell Biol, 12, pp. 613-620
Harbeck, N., Kates, R.E., Look, M.P., Meijer-Van Gelder, M.E., Klijn, J.G., Kruger, A., Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424) (2002) Cancer Res, 62, pp. 4617-4622
Look, M.P., Van Putten, W.L., Duffy, M.J., Harbeck, N., Christensen, I.J., Thomssen, C., Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients (2002) J Natl Cancer Inst, 94, pp. 116-128
Fuchs, T., Allgayer, H., Transcriptional regulation of the urokinase receptor (u-PAR) - A central molecule of invasion and metastasis (2003) Biol Chem, 384, pp. 755-761
Soravia, E., Grebe, A., De Luca, P., Helin, K., Suh, T.T., Degen, J.L., A conserved TATA-less proximal promoter drives basal transcription from the urokinase-type plasminogen activator receptor gene (1995) Blood, 86, pp. 624-635
Allgayer, H., Wang, H., Gallick, G.E., Crabtree, A., Mazar, A., Jones, T., Transcriptional induction of the urokinase receptor gene by a constitutively active Src. Requirement of an upstream motif (-152/-135) bound with Sp1 (1999) J Biol Chem, 274, pp. 18428-18437
Black, A.R., Black, J.D., Azizkhan-Clifford, J., Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer (2001) J Cell Physiol, 188, pp. 143-160
Samson, S.L., Wong, N.C., Role of Sp1 in insulin regulation of gene expression (2002) J Mol Endocrinol, 29, pp. 265-729
Bouwman, P., Philipsen, S., Regulation of the activity of Sp1-related transcription factors (2002) Mol Cell Endocrinol, 195, pp. 27-38
Borellini, F., He, Y.F., Aquino, A., Yu, G., Josephs, S.F., Glazer, R.I., Increased DNA binding and transcriptional activity associated with transcription factor Sp1 in K562 cells transfected with the myeloid-specific c-fes tyrosine kinase gene (1991) J Biol Chem, 266, pp. 15850-15854
Kim, S.J., Onwuta, U.S., Lee, Y.I., Li, R., Botchan, M.R., Robbins, P.D., The retinoblastoma gene product regulates Sp1-mediated transcription (1992) Mol Cell Biol, 12, pp. 2455-2463
Sif, S., Capobianco, A.J., Gilmore, T.D., The v-Rel oncoprotein increases expression from Sp1 site-containing promoters in chicken embryo fibroblasts (1993) Oncogene, 8, pp. 2501-2509
Zannetti, A., Del Vecchio, S., Carriero, M.V., Fonti, R., Franco, P., Botti, G., Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma (2000) Cancer Res, 60, pp. 1546-1551
Schewe, D.M., Leupold, J.H., Boyd, D.D., Lengyel, E.R., Wang, H., Gruetzner, K.U., Tumor-specific transcription factor binding to an activator protein-2/Sp1 element of the urokinase-type plasminogen activator receptor promoter in a first large series of resected gastrointestinal cancers (2003) Clin Cancer Res, 9, pp. 2267-2276
Ibanez-Tallon, I., Ferrai, C., Longobardi, E., Facetti, I., Blasi, F., Crippa, M.P., Binding of Sp1 to the proximal promoter links constitutive expression of the human uPA gene and invasive potential of PC3 cells (2002) Blood, 100, pp. 3325-3332
Benasciutti, E., Pages, G., Kenzior, O., Folk, W., Blasi, F., Crippa, M.P., MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter elements and endogenous gene transcription (2004) Blood, 104, pp. 256-262
Ray, A., Norden, B., Peptide nucleic acid (PNA): Its medical and biotechnical applications and promise for the future (2000) Faseb J, 14, pp. 1041-1060
Romanelli, A., Saviano, M., Pedone, C., Synthetic strategies for obtaining PNA and PNA conjugates (2004) Recent Res Dev Org Chem, 8, pp. 237-254
Dignam, J.D., Lebovitz, R.M., Roeder, R.G., Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei (1983) Nucleic Acids Res, 11, pp. 1475-1489
Darnell Jr., J.E., Transcription factors as targets for cancer therapy (2002) Nat Rev Cancer, 2, pp. 740-749
Mann, M.J., Dzau, V.J., Therapeutic applications of transcription factor decoy oligonucleotides (2000) J Clin Invest, 106, pp. 1071-1075
Cho, Y.S., Kim, M.K., Cheadle, C., Neary, C., Park, Y.G., Becker, K.G., A genomic-scale view of the cAMP response element-enhancer decoy: A tumor target-based genetic tool (2002) Proc Natl Acad Sci USA, 99, pp. 15626-15631
Morishita, R., Tomita, N., Kaneda, Y., Ogihara, T., Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides (2004) Curr Opin Pharmacol, 4, pp. 139-146
Penolazzi, L., Lambertini, E., Borgatti, M., Piva, R., Cozzani, M., Giovannini, I., Decoy oligodeoxynucleotides targeting NF-kappaB transcription factors: Induction of apoptosis in human primary osteoclasts (2003) Biochem Pharmacol, 66, pp. 1189-1198
Wang, L.H., Yang, X.Y., Zhang, X., Mihalic, K., Xiao, W., Farrar, W.L., The cis decoy against the estrogen response element suppresses breast cancer cells via target disrupting c-fos not mitogen-activated protein kinase activity (2003) Cancer Res, 63, pp. 2046-2051
Borgatti, M., Lampronti, I., Romanelli, A., Pedone, C., Saviano, M., Bianchi, N., Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites (2003) J Biol Chem, 278, pp. 7500-7509
Borgatti, M., Romanelli, A., Saviano, M., Pedone, C., Lampronti, I., Breda, L., Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum (2003) Oncol Res, 13, pp. 279-287
Uhlmann, E., Peptide nucleic acids (PNA) and PNA-DNA chimeras: From high binding affinity towards biological function (1998) Biol Chem, 379, pp. 1045-1052
Mann, M.J., Whittemore, A.D., Donaldson, M.C., Belkin, M., Conte, M.S., Polak, J.F., Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: The PREVENT single-centre, randomised, controlled trial (1999) Lancet, 354, pp. 1493-1498
Novak, E.M., Metzger, M., Chammas, R., Da Costa, M., Dantas, K., Manabe, C., Downregulation of TNF-alpha and VEGF expression by Sp1 decoy oligodeoxynucleotides in mouse melanoma tumor (2003) Gene Ther, 10, pp. 1992-1997
Kubo, T., Kinjyo, N., Ikezawa, A., Kambe, T., Fukumori, R., Sp1 decoy oligodeoxynucleotide decreases angiotensin receptor expression and blood pressure in spontaneously hypertensive rats (2003) Brain Res, 992, pp. 1-8
Kawamura, I., Morishita, R., Tsujimoto, S., Manda, T., Tomoi, M., Tomita, N., Intravenous injection of oligodeoxynucleotides to the NF-kappaB binding site inhibits hepatic metastasis of M5076 reticulosarcoma in mice (2001) Gene Ther, 8, pp. 905-912
Matrisian, L.M., Sledge Jr., G.W., Mohla, S., Extracellular proteolysis and cancer: Meeting summary and future directions (2003) Cancer Res, 63, pp. 6105-6109
Coussens, L.M., Fingleton, B., Matrisian, L.M., Matrix metalloproteinase inhibitors and cancer: Trials and tribulations (2002) Science, 295, pp. 2387-2392
Chambers, A. F., Groom, A. C., MacDonald, I. C., Dissemination and growth of cancer cells in metastatic sites (2002) Nat Rev Cancer, 2, pp. 563-57
Andreasen, P. A., Egelund, R., Petersen, H. H., The plasminogen activation system in tumor growth, invasion, and metastasis (2000) Cell Mol Life Sci, 57, pp. 25-40
Look, M. P., Van Putten, W. L., Duffy, M. J., Harbeck, N., Christensen, I. J., Thomssen, C., Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients (2002) J Natl Cancer Inst, 94, pp. 116-128
Black, A. R., Black, J. D., Azizkhan-Clifford, J., Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer (2001) J Cell Physiol, 188, pp. 143-160
Samson, S. L., Wong, N. C., Role of Sp1 in insulin regulation of gene expression (2002) J Mol Endocrinol, 29, pp. 265-729
Kim, S. J., Onwuta, U. S., Lee, Y. I., Li, R., Botchan, M. R., Robbins, P. D., The retinoblastoma gene product regulates Sp1-mediated transcription (1992) Mol Cell Biol, 12, pp. 2455-2463
Schewe, D. M., Leupold, J. H., Boyd, D. D., Lengyel, E. R., Wang, H., Gruetzner, K. U., Tumor-specific transcription factor binding to an activator protein-2/Sp1 element of the urokinase-type plasminogen activator receptor promoter in a first large series of resected gastrointestinal cancers (2003) Clin Cancer Res, 9, pp. 2267-2276
Dignam, J. D., Lebovitz, R. M., Roeder, R. G., Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei (1983) Nucleic Acids Res, 11, pp. 1475-1489
Darnell Jr., J. E., Transcription factors as targets for cancer therapy (2002) Nat Rev Cancer, 2, pp. 740-749
Mann, M. J., Dzau, V. J., Therapeutic applications of transcription factor decoy oligonucleotides (2000) J Clin Invest, 106, pp. 1071-1075
Cho, Y. S., Kim, M. K., Cheadle, C., Neary, C., Park, Y. G., Becker, K. G., A genomic-scale view of the cAMP response element-enhancer decoy: A tumor target-based genetic tool (2002) Proc Natl Acad Sci USA, 99, pp. 15626-15631
Wang, L. H., Yang, X. Y., Zhang, X., Mihalic, K., Xiao, W., Farrar, W. L., The cis decoy against the estrogen response element suppresses breast cancer cells via target disrupting c-fos not mitogen-activated protein kinase activity (2003) Cancer Res, 63, pp. 2046-2051
Mann, M. J., Whittemore, A. D., Donaldson, M. C., Belkin, M., Conte, M. S., Polak, J. F., Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: The PREVENT single-centre, randomised, controlled trial (1999) Lancet, 354, pp. 1493-1498
Novak, E. M., Metzger, M., Chammas, R., Da Costa, M., Dantas, K., Manabe, C., Downregulation of TNF-alpha and VEGF expression by Sp1 decoy oligodeoxynucleotides in mouse melanoma tumor (2003) Gene Ther, 10, pp. 1992-1997
Matrisian, L. M., Sledge Jr., G. W., Mohla, S., Extracellular proteolysis and cancer: Meeting summary and future directions (2003) Cancer Res, 63, pp. 6105-6109
Coussens, L. M., Fingleton, B., Matrisian, L. M., Matrix metalloproteinase inhibitors and cancer: Trials and tribulations (2002) Science, 295, pp. 2387-2392
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2005 Nov 1; 70(9): 1277-1287.
Tipo di articolo: Journal Article,
Impact factor: 3.617, Impact factor a 5 anni: 4.772
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-25644442324&partnerID=40&md5=ee6ad4844b2546aad2114f23c7770227
Parole chiave: Breast Cancer, Peptide Nucleic Acid, Pna-Dna Chimera, Sp1 Transcription Factor, Urokinase Receptor, Complementary Dna, Liposome, Oligonucleotide, Transcription Factor Sp1, Amino Acid Sequence, Article, Cancer Cell, Cancer Inhibition, Cell Migration, Cell Motility, Covalent Bond, Dna Strand, Down Regulation, Genetic Transfection, Human, Human Cell, In Vitro Study, Inhibition Kinetics, Metastasis, Priority Journal, Protein Binding, Protein Expression, Protein Function, Receptor Upregulation, Breast Neoplasms, Cell Line, Tumor, Cell Movement, Female, Cell Surface,
Affiliazioni:
*** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche, Via S. Pansini 5, 80131 Naples, Italy
Istituto di Endocrinologia Ed Oncologia Sperimentale, Consiglio Nazionale Delle Ricerche, Naples, Italy
Istituto Internazionale di Genetica e Biofisica, Consiglio Nazionale Delle Ricerche, Naples, Italy
Dipartimento di Scienze Biomorfologiche e Funzionali, Universita' Federico II, Naples, Italy
Riferimenti:
Chambers, A.F., Groom, A.C., MacDonald, I.C., Dissemination and growth of cancer cells in metastatic sites (2002) Nat Rev Cancer, 2, pp. 563-57
Andreasen, P.A., Egelund, R., Petersen, H.H., The plasminogen activation system in tumor growth, invasion, and metastasis (2000) Cell Mol Life Sci, 57, pp. 25-40
Blasi, F., Carmeliet, P., UPAR: A versatile signalling orchestrator (2002) Nat Rev Mol Cell Biol, 3, pp. 932-943
Ossowski, L., Aguirre-Ghiso, J.A., Urokinase receptor and integrin partnership: Coordination of signaling for cell adhesion, migration and growth (2000) Curr Opin Cell Biol, 12, pp. 613-620
Harbeck, N., Kates, R.E., Look, M.P., Meijer-Van Gelder, M.E., Klijn, J.G., Kruger, A., Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424) (2002) Cancer Res, 62, pp. 4617-4622
Look, M.P., Van Putten, W.L., Duffy, M.J., Harbeck, N., Christensen, I.J., Thomssen, C., Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients (2002) J Natl Cancer Inst, 94, pp. 116-128
Fuchs, T., Allgayer, H., Transcriptional regulation of the urokinase receptor (u-PAR) - A central molecule of invasion and metastasis (2003) Biol Chem, 384, pp. 755-761
Soravia, E., Grebe, A., De Luca, P., Helin, K., Suh, T.T., Degen, J.L., A conserved TATA-less proximal promoter drives basal transcription from the urokinase-type plasminogen activator receptor gene (1995) Blood, 86, pp. 624-635
Allgayer, H., Wang, H., Gallick, G.E., Crabtree, A., Mazar, A., Jones, T., Transcriptional induction of the urokinase receptor gene by a constitutively active Src. Requirement of an upstream motif (-152/-135) bound with Sp1 (1999) J Biol Chem, 274, pp. 18428-18437
Black, A.R., Black, J.D., Azizkhan-Clifford, J., Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer (2001) J Cell Physiol, 188, pp. 143-160
Samson, S.L., Wong, N.C., Role of Sp1 in insulin regulation of gene expression (2002) J Mol Endocrinol, 29, pp. 265-729
Bouwman, P., Philipsen, S., Regulation of the activity of Sp1-related transcription factors (2002) Mol Cell Endocrinol, 195, pp. 27-38
Borellini, F., He, Y.F., Aquino, A., Yu, G., Josephs, S.F., Glazer, R.I., Increased DNA binding and transcriptional activity associated with transcription factor Sp1 in K562 cells transfected with the myeloid-specific c-fes tyrosine kinase gene (1991) J Biol Chem, 266, pp. 15850-15854
Kim, S.J., Onwuta, U.S., Lee, Y.I., Li, R., Botchan, M.R., Robbins, P.D., The retinoblastoma gene product regulates Sp1-mediated transcription (1992) Mol Cell Biol, 12, pp. 2455-2463
Sif, S., Capobianco, A.J., Gilmore, T.D., The v-Rel oncoprotein increases expression from Sp1 site-containing promoters in chicken embryo fibroblasts (1993) Oncogene, 8, pp. 2501-2509
Zannetti, A., Del Vecchio, S., Carriero, M.V., Fonti, R., Franco, P., Botti, G., Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma (2000) Cancer Res, 60, pp. 1546-1551
Schewe, D.M., Leupold, J.H., Boyd, D.D., Lengyel, E.R., Wang, H., Gruetzner, K.U., Tumor-specific transcription factor binding to an activator protein-2/Sp1 element of the urokinase-type plasminogen activator receptor promoter in a first large series of resected gastrointestinal cancers (2003) Clin Cancer Res, 9, pp. 2267-2276
Ibanez-Tallon, I., Ferrai, C., Longobardi, E., Facetti, I., Blasi, F., Crippa, M.P., Binding of Sp1 to the proximal promoter links constitutive expression of the human uPA gene and invasive potential of PC3 cells (2002) Blood, 100, pp. 3325-3332
Benasciutti, E., Pages, G., Kenzior, O., Folk, W., Blasi, F., Crippa, M.P., MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter elements and endogenous gene transcription (2004) Blood, 104, pp. 256-262
Ray, A., Norden, B., Peptide nucleic acid (PNA): Its medical and biotechnical applications and promise for the future (2000) Faseb J, 14, pp. 1041-1060
Romanelli, A., Saviano, M., Pedone, C., Synthetic strategies for obtaining PNA and PNA conjugates (2004) Recent Res Dev Org Chem, 8, pp. 237-254
Dignam, J.D., Lebovitz, R.M., Roeder, R.G., Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei (1983) Nucleic Acids Res, 11, pp. 1475-1489
Darnell Jr., J.E., Transcription factors as targets for cancer therapy (2002) Nat Rev Cancer, 2, pp. 740-749
Mann, M.J., Dzau, V.J., Therapeutic applications of transcription factor decoy oligonucleotides (2000) J Clin Invest, 106, pp. 1071-1075
Cho, Y.S., Kim, M.K., Cheadle, C., Neary, C., Park, Y.G., Becker, K.G., A genomic-scale view of the cAMP response element-enhancer decoy: A tumor target-based genetic tool (2002) Proc Natl Acad Sci USA, 99, pp. 15626-15631
Morishita, R., Tomita, N., Kaneda, Y., Ogihara, T., Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides (2004) Curr Opin Pharmacol, 4, pp. 139-146
Penolazzi, L., Lambertini, E., Borgatti, M., Piva, R., Cozzani, M., Giovannini, I., Decoy oligodeoxynucleotides targeting NF-kappaB transcription factors: Induction of apoptosis in human primary osteoclasts (2003) Biochem Pharmacol, 66, pp. 1189-1198
Wang, L.H., Yang, X.Y., Zhang, X., Mihalic, K., Xiao, W., Farrar, W.L., The cis decoy against the estrogen response element suppresses breast cancer cells via target disrupting c-fos not mitogen-activated protein kinase activity (2003) Cancer Res, 63, pp. 2046-2051
Borgatti, M., Lampronti, I., Romanelli, A., Pedone, C., Saviano, M., Bianchi, N., Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites (2003) J Biol Chem, 278, pp. 7500-7509
Borgatti, M., Romanelli, A., Saviano, M., Pedone, C., Lampronti, I., Breda, L., Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum (2003) Oncol Res, 13, pp. 279-287
Uhlmann, E., Peptide nucleic acids (PNA) and PNA-DNA chimeras: From high binding affinity towards biological function (1998) Biol Chem, 379, pp. 1045-1052
Mann, M.J., Whittemore, A.D., Donaldson, M.C., Belkin, M., Conte, M.S., Polak, J.F., Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: The PREVENT single-centre, randomised, controlled trial (1999) Lancet, 354, pp. 1493-1498
Novak, E.M., Metzger, M., Chammas, R., Da Costa, M., Dantas, K., Manabe, C., Downregulation of TNF-alpha and VEGF expression by Sp1 decoy oligodeoxynucleotides in mouse melanoma tumor (2003) Gene Ther, 10, pp. 1992-1997
Kubo, T., Kinjyo, N., Ikezawa, A., Kambe, T., Fukumori, R., Sp1 decoy oligodeoxynucleotide decreases angiotensin receptor expression and blood pressure in spontaneously hypertensive rats (2003) Brain Res, 992, pp. 1-8
Kawamura, I., Morishita, R., Tsujimoto, S., Manda, T., Tomoi, M., Tomita, N., Intravenous injection of oligodeoxynucleotides to the NF-kappaB binding site inhibits hepatic metastasis of M5076 reticulosarcoma in mice (2001) Gene Ther, 8, pp. 905-912
Matrisian, L.M., Sledge Jr., G.W., Mohla, S., Extracellular proteolysis and cancer: Meeting summary and future directions (2003) Cancer Res, 63, pp. 6105-6109
Coussens, L.M., Fingleton, B., Matrisian, L.M., Matrix metalloproteinase inhibitors and cancer: Trials and tribulations (2002) Science, 295, pp. 2387-2392
Chambers, A. F., Groom, A. C., MacDonald, I. C., Dissemination and growth of cancer cells in metastatic sites (2002) Nat Rev Cancer, 2, pp. 563-57
Andreasen, P. A., Egelund, R., Petersen, H. H., The plasminogen activation system in tumor growth, invasion, and metastasis (2000) Cell Mol Life Sci, 57, pp. 25-40
Look, M. P., Van Putten, W. L., Duffy, M. J., Harbeck, N., Christensen, I. J., Thomssen, C., Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients (2002) J Natl Cancer Inst, 94, pp. 116-128
Black, A. R., Black, J. D., Azizkhan-Clifford, J., Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer (2001) J Cell Physiol, 188, pp. 143-160
Samson, S. L., Wong, N. C., Role of Sp1 in insulin regulation of gene expression (2002) J Mol Endocrinol, 29, pp. 265-729
Kim, S. J., Onwuta, U. S., Lee, Y. I., Li, R., Botchan, M. R., Robbins, P. D., The retinoblastoma gene product regulates Sp1-mediated transcription (1992) Mol Cell Biol, 12, pp. 2455-2463
Schewe, D. M., Leupold, J. H., Boyd, D. D., Lengyel, E. R., Wang, H., Gruetzner, K. U., Tumor-specific transcription factor binding to an activator protein-2/Sp1 element of the urokinase-type plasminogen activator receptor promoter in a first large series of resected gastrointestinal cancers (2003) Clin Cancer Res, 9, pp. 2267-2276
Dignam, J. D., Lebovitz, R. M., Roeder, R. G., Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei (1983) Nucleic Acids Res, 11, pp. 1475-1489
Darnell Jr., J. E., Transcription factors as targets for cancer therapy (2002) Nat Rev Cancer, 2, pp. 740-749
Mann, M. J., Dzau, V. J., Therapeutic applications of transcription factor decoy oligonucleotides (2000) J Clin Invest, 106, pp. 1071-1075
Cho, Y. S., Kim, M. K., Cheadle, C., Neary, C., Park, Y. G., Becker, K. G., A genomic-scale view of the cAMP response element-enhancer decoy: A tumor target-based genetic tool (2002) Proc Natl Acad Sci USA, 99, pp. 15626-15631
Wang, L. H., Yang, X. Y., Zhang, X., Mihalic, K., Xiao, W., Farrar, W. L., The cis decoy against the estrogen response element suppresses breast cancer cells via target disrupting c-fos not mitogen-activated protein kinase activity (2003) Cancer Res, 63, pp. 2046-2051
Mann, M. J., Whittemore, A. D., Donaldson, M. C., Belkin, M., Conte, M. S., Polak, J. F., Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: The PREVENT single-centre, randomised, controlled trial (1999) Lancet, 354, pp. 1493-1498
Novak, E. M., Metzger, M., Chammas, R., Da Costa, M., Dantas, K., Manabe, C., Downregulation of TNF-alpha and VEGF expression by Sp1 decoy oligodeoxynucleotides in mouse melanoma tumor (2003) Gene Ther, 10, pp. 1992-1997
Matrisian, L. M., Sledge Jr., G. W., Mohla, S., Extracellular proteolysis and cancer: Meeting summary and future directions (2003) Cancer Res, 63, pp. 6105-6109
Coussens, L. M., Fingleton, B., Matrisian, L. M., Matrix metalloproteinase inhibitors and cancer: Trials and tribulations (2002) Science, 295, pp. 2387-2392
Sp1 regulates the activation of many genes involved in tumor growth, apoptosis, and angiogenesis. We have previously shown the involvement of Sp1 in the up-regulation of urokinase receptor (uPAR) expression, a key molecule in tumor invasion and metastasis. Here, we investigated whether a marked down-regulation of Sp1 activity may inhibit uPAR expression and migration ability of MDA-MB-231 breast cancer cells. To this end, we tested the decoy ability of a novel peptide nucleic acid (PNA)-DNA chimera which carries a central DNA strand, containing Sp1-binding sequence, covalently linked to two PNA fragments at both ends (PNA-DNA-PNA, PDP). The chimera was synthesized, annealed with complementary DNA (PDP-DNA), and then tested for its ability to bind Sp1 both in vitro and in living MDA-MB-231 breast cancer cells in the presence of urokinase (uPA). This PDP-DNA decoy molecule efficiently competes for the binding to endogenous Sp1 in nuclear extracts, and upon transfection with liposomal vectors, causes a marked decrease of available Sp1 in both untreated and uPA-treated MDA-MB-231 cells. Accordingly, both uPA-dependent enhancement of uPAR expression and cell migration were strongly reduced in transfected cells. Interestingly, a detectable inhibitory effect is also observed in breast cancer cells exposed to PDP-DNA in the absence of transfection reagents. Finally, the inhibitory effect of PDP-DNA appeared to be stronger than that observed with oligonucleotides carrying Sp1 consensus sequence. Our findings show that this novel PNA-DNA chimera, containing Sp1 consensus sequence, effectively inhibits Sp1 activity, uPAR expression, and motility of breast cancer cells indicating its potential therapeutic use to prevent tumor dissemination. (c) 2005 Elsevier Inc. All rights reserved.
Nessun risultato. |
| 99mTc-MIBI in the Evaluation of 7 Breast Cancer Biology (dominio pubblico) (139 visite) |
| Aptamer-mediated impairment of EGFR-integrin αvβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers (dominio pubblico) (170 visite) |
| Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRβ Aptamer. (dominio pubblico) (163 visite) |
| Recent Advances in Nuclear Imaging of Receptor Expression to Guide Targeted Therapies in Breast Cancer (dominio pubblico) (51 visite) |
| Targeted imaging and inhibition of triple-negative breast cancer metastases by a PDGFRβ aptamer (dominio pubblico) (96 visite) |
| Therapeutic Potential of a Novel αvβ3 Antagonist to Hamper the Aggressiveness of Mesenchymal Triple Negative Breast Cancer Sub-Type (dominio pubblico) (62 visite) |
Vai a fine pagina Versione per copia e incolla facile Esporta tutto in BibTeX Esporta tutto in EndNote
Avitabile C, Diaferia C, Roviello V, Altamura D, Giannini C, Vitagliano L, Accardo A, Romanelli A
* Fluorescence and Morphology of Self-Assembled Nucleobases and Their Diphenylalanine Hybrid Aggregates (41 visite)
Chemistry (ISSN: 0947-6539linking), 2019 Nov 22; 25(65): 14850-14857.
Impact Factor: 5.476
Dettagli Esporta in BibTeX Esporta in EndNote
Salvatore B, Caprio MG, Hill BS, Sarnella A, Roviello GN, Zannetti A
* Recent Advances in Nuclear Imaging of Receptor Expression to Guide Targeted Therapies in Breast Cancer (104 visite) (PDF 51 visite)
Cancers (ISSN: 2072-6694linking), 2019 Oct 22; 11(10): N/D-N/D.
Impact Factor: 6.162
Dettagli Esporta in BibTeX Esporta in EndNote
Piacenti V, Langella E, Autiero I, Nolan JC, Piskareva O, Adamo MFA, Saviano M, Moccia M
* A combined experimental and computational study on peptide nucleic acid (PNA) analogues of tumor suppressive miRNA-34a (100 visite)
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2019 Oct; 91: 103165-103165.
Impact Factor: 3.9
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito MV, Minopoli G, Esposito L, D'Argenio V, Di Maggio F, Sasso E, D'Aiuto M, Zambrano N, Salvatore F
* A Functional Analysis of the Unclassified Pro2767Ser BRCA2 Variant Reveals Its Potential Pathogenicity that Acts by Hampering DNA Binding and Homology-Mediated DNA Repair (50 visite)
Cancers (ISSN: 2072-6694linking), 2019 Sep 28; 11(10): N/D-N/D.
Impact Factor: 6.102
Dettagli Esporta in BibTeX Esporta in EndNote
Hill BS, Sarnella A, D'Avino G, Zannetti A
* Recruitment of stromal cells into tumour microenvironment promote the metastatic spread of breast cancer (84 visite)
Semin Cancer Biol (ISSN: 1044-579xlinking), 2019 Aug 1; N/D: N/D-N/D.
Impact Factor: 9.658
Dettagli Esporta in BibTeX Esporta in EndNote
Fellin F, Iacco M, D'Avino V, Tommasino F, Farace P, Palma G, Conson M, Giacomelli I, Zucchetti C, Falcinelli L, Amichetti M, Aristei C, Cella L
* Potential skin morbidity reduction with intensity-modulated proton therapy for breast cancer with nodal involvement (42 visite)
Acta Oncol (ISSN: 0284-186xlinking), 2019 Jun; 58 (6 ): 934-942.
Impact Factor: 2.997
Dettagli Esporta in BibTeX Esporta in EndNote
Hill BS, Sarnella A, Capasso D, Comegna D, Del Gatto A, Gramanzini M, Albanese S, Saviano M, Zaccaro L, Zannetti A
* Therapeutic Potential of a Novel alphavbeta(3) Antagonist to Hamper the Aggressiveness of Mesenchymal Triple Negative Breast Cancer Sub-Type (160 visite) (PDF 62 visite)
Cancers (ISSN: 2072-6694linking), 2019 Jan 24; 11(2): N/D-N/D.
Impact Factor: 5.326
Dettagli Esporta in BibTeX Esporta in EndNote
D'Amora A, Cucciolito M, E , Iannitti R, Morelli G, Palumbo R, Ruffo F, Tesauro D
* Pyridine Ruthenium(III) complexes entrapped in liposomes with enhanced cytotoxic properties in PC-3 prostate cancer cells (61 visite)
Journal Of Drug Delivery Science And Technology, 2019; 51: 552-558.
Impact Factor: 2.606
Dettagli Esporta in BibTeX Esporta in EndNote
Camorani S, Hill B, Collina F, Gargiulo S, Napolitano M, Cantile M, Di Bonito M, Botti G, Fedele M, Zannetti A, Cerchia L
* Targeted imaging and inhibition of triple-negative breast cancer metastases by a PDGFRβ aptamer (421 visite) (PDF 96 visite)
Theranostics (ISSN: 1838-7640, 1838-7640electronic, 1838-7640linking), 2018 Oct 6; 8(18): 5178-5199.
Impact Factor: 8.537
Dettagli Esporta in BibTeX Esporta in EndNote
Carafa V, Nebbioso A, Cuomo F, Rotili D, Cobellis G, Bontempo P, Baldi A, Spugnini EP, Citro G, Chambery A, Russo R, Ruvo M, Ciana P, Maravigna L, Shaik J, Radaelli E, De Antonellis P, Tarantino D, Pirolli A, Ragno R, Zollo M, Stunnenberg HG, Mai A, Altucci L
* RIP1-HAT1-SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer (95 visite)
Clin Cancer Res (ISSN: 1078-0432print, 1078-0432linking), 2018 Jun 15; 24(12): 2886-2900.
Impact Factor: 6.488
Dettagli Esporta in BibTeX Esporta in EndNote
Avitabile C, Diaferia C, Della Ventura B, Mercurio FA, Leone M, Roviello V, Saviano M, Velotta R, Morelli G, Accardo A, Romanelli A
* Self-Assembling of Fmoc-GC Peptide Nucleic Acid Dimers into Highly Fluorescent Aggregates (217 visite)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Mar 26; 24(18): 4729-4735.
Impact Factor: 5.476
Dettagli Esporta in BibTeX Esporta in EndNote
Di Gregorio E, Ferrauto G, Lanzardo S, Gianolio E, Aime S
* Early diagnosis of breast cancer by using Fast field cycling relaxometry (FFC-NMRD): investigations of ex-vivo murine breast tissue (118 visite)
Breast Cancer Radiology, 2018; N/D: N/D-N/D.
Impact Factor: 1.712
Dettagli Esporta in BibTeX Esporta in EndNote
Fusella F, Secli L, Busso E, Krepelova A, Moiso E, Rocca S, Conti L, Annaratone L, Rubinetto C, Mello-grand M, Singh V, Chiorino G, Silengo L, Altruda F, Turco E, Morotti A, Oliviero S, Castellano I, Cavallo F, Provero P, Tarone G, Brancaccio M
* The IKK/NF-kappaB signaling pathway requires Morgana to drive breast cancer metastasis (103 visite)
Nat Commun (ISSN: 2041-1723, 2041-1723electronic), 2017 Nov 21; 8(1): 1636-1636.
Impact Factor: 12.353
Dettagli Esporta in BibTeX Esporta in EndNote
Piras L, Avitabile C, D'Andrea LD, Saviano M, Romanelli A
* Detection of oligonucleotides by PNA-peptide conjugates recognizing the biarsenical fluorescein complex FlAsH-EDT2 (158 visite)
Biochem Bioph Res Co (ISSN: 0006-291x), 2017 Sep 15; N/D: N/D-N/D.
Impact Factor: 2.559
Dettagli Esporta in BibTeX Esporta in EndNote
Camorani S, Hill BS, Fontanella R, Greco A, Gramanzini M, Auletta L, Gargiulo S, Albanese S, Lucarelli E, Cerchia L, Zannetti A
* Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRbeta Aptamer (531 visite) (PDF 163 visite)
Theranostics (ISSN: 1838-7640, 1838-7640electronic), 2017 Aug 22; 7(14): 3595-3607.
Impact Factor: 8.537
Dettagli Esporta in BibTeX Esporta in EndNote
Romeo V, Cuocolo R, Liuzzi R, Riccardi A, Accurso A, Acquaviva A, Buonocore R, Imbriaco M
* Preliminary Results of a Simplified Breast MRI Protocol to Characterize Breast Lesions: Comparison with a Full Diagnostic Protocol and a Review of the Current Literature (154 visite)
Acad Radiol (ISSN: 1076-6332, 1878-4046electronic), 2017 Jun 01; N/D: N/D-N/D.
Impact Factor: 2.11
Dettagli Esporta in BibTeX Esporta in EndNote
Camorani S, Crescenzi E, Gramanzini M, Fedele M, Zannetti A, Cerchia L
* Aptamer-mediated impairment of EGFR-integrin alphavbeta3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers (282 visite) (PDF 170 visite)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Apr 20; 7: 46659-46659.
Impact Factor: 4.122
Dettagli Esporta in BibTeX Esporta in EndNote
Longo DL, Moustaghfir FZ, Zerbo A, Consolino L, Anemone A, Bracesco M, Aime S
* EXCI-CEST: Exploiting pharmaceutical excipients as MRI-CEST contrast agents for tumor imaging (168 visite)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2017; 525(1): 275-281.
Impact Factor: 3.862
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Del Zoppo L, Morelli G, Condorelli D, Barresi V, Musso N, Spampinato G, Bellia F, Tabbì G, Rizzarelli E
* Liposome antibody-ionophore conjugate antiproliferative activity increases by cellular metallostasis alteration (116 visite)
Med Chem Comm, 2016 Sep; 7: 2364-2367.
Impact Factor: 2.319
Dettagli Esporta in BibTeX Esporta in EndNote
Ferrauto G, Delli Castelli D, Di Gregorio E, Terreno E, Aime S
* LipoCEST and cellCEST imaging agents: opportunities and challenges (223 visite)
Wires Nanomed Nanobi (ISSN: 1939-5116), 2016 Jul; 8(4): 602-618.
Impact Factor: 4.761
Dettagli Esporta in BibTeX Esporta in EndNote
Soprano M, Sorriento D, Rusciano MR, Maione AS, Limite G, Forestieri P, D'Angelo D, D'Alessio M, Campiglia P, Formisano P, Iaccarino G, Bianco R, Illario M
* Oxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer Cells (139 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2016 Jun 9; 11(6): e0155970-e0155970.
Impact Factor: 2.806
Dettagli Esporta in BibTeX Esporta in EndNote
Nicastro MC, Spigolon D, Librizzi F, Moran O, Ortore MG, Bulone D, Biagio PLS, Carrotta R
* Amyloid β-peptide insertion in liposomes containing GM1-cholesterol domains (157 visite)
Biophys Chem (ISSN: 0301-4622, 0301-4622linking), 2016; 208: 9-16.
Impact Factor: 2.402
Dettagli Esporta in BibTeX Esporta in EndNote
Pastore F, Conson M, D'Avino V, Palma G, Liuzzi R, Solla R, Farella A, Salvatore M, Cella L, Pacelli R
* Dose-surface analysis for prediction of severe acute radio-induced skin toxicity in breast cancer patients (261 visite)
Acta Oncol (ISSN: 0284-186x), 2016; 55(4): 466-473.
Impact Factor: 3.156
Dettagli Esporta in BibTeX Esporta in EndNote
Ringhieri P, Pannunzio A, Boccarelli A, Morelli G, Coluccia M, Tesauro D
* Effect of cisplatin containing liposomes formulated by unsaturated chain-containing lipids on gynecological tumor cells (197 visite)
J Liposome Res (ISSN: 0898-2104), 2016; N/D: 1-6.
Impact Factor: 1.971
Dettagli Esporta in BibTeX Esporta in EndNote
Consolino L, Longo DL, Dastrù W, Cutrin JC, Dettori D, Lanzardo S, Oliviero S, Cavallo F, Aime S
* Functional imaging of the angiogenic switch in a transgenic mouse model of human breast cancer by dynamic contrast enhanced magnetic resonance imaging (193 visite)
Int J Cancer (ISSN: 0020-7136), 2016; N/D: N/D-N/D.
Impact Factor: 6.513
Dettagli Esporta in BibTeX Esporta in EndNote
Ringhieri P, Avitabile C, Saviano M, Morelli G, Romanelli A, Accardo A
* The influence of liposomal formulation on the incorporation and retention of PNA oligomers (80 visite)
Colloid Surface B (ISSN: 0927-7765), 2016; 145: 462-469.
Impact Factor: 3.887
Dettagli Esporta in BibTeX Esporta in EndNote
Autiero I, Saviano M, Langella E
* Conformational studies of chiral D-Lys-PNA and achiral PNA system in binding with DNA or RNA through a molecular dynamics approach (298 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2015 Feb 16; 91: 109-117.
Impact Factor: 3.902
Dettagli Esporta in BibTeX Esporta in EndNote
Rizzitelli S, Giustetto P, Cutrin JC, Delli Castelli D, Boffa C, Ruzza M, Menchise V, Molinari F, Aime S, Terreno E
* Sonosensitive theranostic liposomes for preclinical in vivo MRI-guided visualization of doxorubicin release stimulated by pulsed low intensity non-focused ultrasound (313 visite)
J Control Release (ISSN: 0168-3659), 2015 Jan 24; 202: 21-30.
Impact Factor: 7.441
Dettagli Esporta in BibTeX Esporta in EndNote
Galdiero S, Falanga A, Morelli G, Galdiero M
* gH625: A milestone in understanding the many roles of membranotropic peptides (303 visite)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2015 Jan; 1848(PA): 16-25.
Impact Factor: 5.158
Dettagli Esporta in BibTeX Esporta in EndNote
Longo DL, Dastrù W, Consolino L, Espak M, Arigoni M, Cavallo F, Aime S
* Cluster analysis of quantitative parametric maps from DCE-MRI: Application in evaluating heterogeneity of tumor response to antiangiogenic treatment (345 visite)
Magn Reson Imaging (ISSN: 0730-725x), 2015; 33(6): 725-736.
Impact Factor: 1.98
Dettagli Esporta in BibTeX Esporta in EndNote
Yousif AM, Minopoli M, Bifulco K, Ingangi V, Di Carluccio G, Merlino F, Motti ML, Grieco P, Carriero MV
* Cyclization of the urokinase receptor-derived Ser-Arg-Ser-Arg-Tyr peptide generates a potent inhibitor of trans-endothelial migration of monocytes (283 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2015; 10(5): N/D-N/D.
Impact Factor: 3.057
Dettagli Esporta in BibTeX Esporta in EndNote
Avitabile C, Accardo A, Ringhieri P, Morelli G, Saviano M, Montagner G, Fabbri E, Gallerani E, Gambari R, Romanelli A
* Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery (274 visite)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812), 2015; 26(8): 1533-1541.
Impact Factor: 4.5
Dettagli Esporta in BibTeX Esporta in EndNote
Ringhieri P, Diaferia C, Galdiero S, Palumbo R, Morelli G, Accardo A
* Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery (295 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 415-425.
Impact Factor: 1.951
Dettagli Esporta in BibTeX Esporta in EndNote
Morelli G, Saviano M, Grieco P
* The renaissance era of peptides in drug discovery at the 14th Naples workshop on bioactive peptides (258 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 321-322.
Impact Factor: 1.951
Dettagli Esporta in BibTeX Esporta in EndNote
Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M
* Exploitation of viral properties for intracellular delivery (316 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2014 Jul; 20(7): 468-478.
Impact Factor: 1.546
Dettagli Esporta in BibTeX Esporta in EndNote
Gallicchio R, Giacomobono S, Nardelli A, Pellegrino T, Simeon V, Gattozzi D, Maddalena F, Mainenti PP, Storto G
* Palliative Treatment Of Bone Metastases With Samarium-153 Edtmp At Onset Of Pain (270 visite)
J Bone Miner Metab (ISSN: 0914-8779), 2014 Jul; 32(4): 434-440.
Impact Factor: 2.46
Dettagli Esporta in BibTeX Esporta in EndNote
Carriero MV, Bifulco K, Minopoli M, Lista L, Maglio O, Mele L, Di Carluccio G, De Rosa M, Pavone V
* UPARANT: a urokinase receptor-derived peptide inhibitor of VEGF-driven angiogenesis with enhanced stability and in vitro and in vivo potency (307 visite)
Mol Cancer Ther (ISSN: 1535-7163, 1538-8514electronic), 2014 May; 13(5): 1092-1104.
Impact Factor: 5.683
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (345 visite)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
Dettagli Esporta in BibTeX Esporta in EndNote
Musumeci D, Roviello GN, Montesarchio D
* An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies (279 visite)
Pharmacol Ther (ISSN: 0163-7258, 0163-7258linking), 2014 Mar; 141(3): 347-357.
Impact Factor: 9.723
Dettagli Esporta in BibTeX Esporta in EndNote
Formisano L, Nappi L, Rosa R, Marciano R, D'Amato C, D'Amato V, Damiano V, Raimondo L, Iommelli F, Scorziello A, Troncone G, Veneziani BM, Parsons SJ, De Placido S, Bianco R
* Epidermal growth factor-receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models (239 visite)
Breast Cancer Res Biomed Central Ltd (ISSN: 1465-5411), 2014; 16(3): R45-R45.
Impact Factor: 0.635
Dettagli Esporta in BibTeX Esporta in EndNote
Autiero I, Saviano M, Langella E
* Molecular Dynamics Simulations Of Pna-Pna And Pna-Dna Duplexes By The Use Of New Parameters Implemented In The Gromacs Package: A Conformational And Dynamics Study (265 visite)
Phys Chem Chem Phys (ISSN: 1463-9076, 1463-3907, 1463-9084electronic), 2014; 16(5): 1868-1874.
Impact Factor: 4.493
Dettagli Esporta in BibTeX Esporta in EndNote
Pastore F, Faiella A, Solla R, Farella A, Cella L, Liuzzi R, Salzano G, Conson M, Salvatore M, Pacelli R
* Psoriasis In Breast Cancer: Incidence And Impact On Radioinduced Skin Toxicity (196 visite)
Radiother Oncol (ISSN: 0167-8140, 1879-0887), 2014; 111: 486-486.
Impact Factor: 4.363
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, D'Alessandro C, Pedone C
* Synthesis of a thymine-functionalized nucleoamino acid for the solid phase assembly of cationic nucleopeptides (299 visite)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2013 Oct; 45(4): 779-784.
Impact Factor: 3.653
Dettagli Esporta in BibTeX Esporta in EndNote
Galdiero S, Falanga A, Cantisani M, Vitiello M, Morelli G, Galdiero M
* Peptide-Lipid Interactions: Experiments and Applications (418 visite)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2013 Sep; 14(9): 18758-18789.
Impact Factor: 2.339
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Tesauro D, Morelli G
* Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors (268 visite)
Polym J (ISSN: 0032-3896), 2013 May; 45(5): 481-493.
Impact Factor: 1.554
Dettagli Esporta in BibTeX Esporta in EndNote
Catanzaro V, Gringeri CV, Menchise V, Padovan S, Boffa C, Dastru W, Chaabane L, Digilio G, Aime S
* A R2p/R1p ratiometric procedure to assess matrix metalloproteinase-2 activity by magnetic resonance imaging (248 visite)
Angew Chem Int Ed (ISSN: 1433-7851, 1521-3773electronic), 2013 Apr 2; 52(14): 3926-3930.
Impact Factor: 11.336
Dettagli Esporta in BibTeX Esporta in EndNote
Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (289 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Impact Factor: 1.862
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (253 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
Dettagli Esporta in BibTeX Esporta in EndNote
Pacelli R, Conson M, Cella L, Liuzzi R, Troncone G, Iorio V, Solla R, Farella A, Scala S, Pagliarulo C, Salvatore M
* Radiation therapy following surgery for localized breast cancer: Outcome prediction by classical prognostic factors and approximated genetic subtypes (221 visite)
J Rad Res Journal Of Radiation Research (ISSN: 1349-9157, 0449-3060, 1349-9157electronic), 2013 Mar 1; 54(2): 292-298.
Impact Factor: 1.691
Dettagli Esporta in BibTeX Esporta in EndNote
Cella L, Conson M, Pressello MC, Molinelli S, Schneider U, Donato V, Orecchia R, Salvatore M, Pacelli R
* Hodgkin's lymphoma emerging radiation treatment techniques: Trade-offs between late radio-induced toxicities and secondary malignant neoplasms (243 visite)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2013 Jan 30; 8(1): 22-22.
Impact Factor: 2.36
Dettagli Esporta in BibTeX Esporta in EndNote
Zanoli LM, Licciardello M, D'Agata R, Lantano C, Calabretta A, Corradini R, Marchelli R, Spoto G
* Peptide nucleic acid molecular beacons for the detection of PCR amplicons in droplet-based microfluidic devices (170 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 615-624.
Impact Factor: 3.578
Dettagli Esporta in BibTeX Esporta in EndNote
Conson M, Faiella A, Iorio V, Cella L, Liuzzi R, Solla R, Romanelli P, Farella A, Salvatore M, Pacelli R
* Her-2 Subtype And Age Affect Local Control In Breast Cancer (234 visite)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2013; 106: N/D-N/D.
Impact Factor: 4.857
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Ringhieri P, Tesauro D, Morelli G
* Liposomes derivatized with tetrabranched neurotensin peptides via click chemistry reactions (259 visite)
New J Chem (ISSN: 1144-0546), 2013; 37(11): 3528-3534.
Impact Factor: 3.159
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Leone M, Tesauro D, Aufiero R, Bénarouche A, Cavalier JF, Longhi S, Carriere F, Rossi F
* Solution conformational features and interfacial properties of an intrinsically disordered peptide coupled to alkyl chains: A new class of peptide amphiphiles (283 visite)
Mol Biosyst (ISSN: 1742-206x), 2013; 9(6): 1401-1410.
Impact Factor: 3.183
Dettagli Esporta in BibTeX Esporta in EndNote
Cella L, Liuzzi R, Conson M, D'Avino V, Salvatore M, Pacelli R
* Development of multivariate NTCP models for radiation-induced hypothyroidism: A comparative analysis (281 visite) (PDF 179 visite)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2012 Dec 27; 7(1): 224-224.
Impact Factor: 2.107
Dettagli Esporta in BibTeX Esporta in EndNote
Berisio R
* Learning from pathogens: Exploiting host-pathogen liaison for therapeutic development (224 visite)
Curr Protein Pept Sci (ISSN: 1389-2037), 2012 Dec; 13(8): 697-698.
Impact Factor: 2.326
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (269 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Mansi R, Salzano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Ziaco B, Tesauro D, Aloj L, De Rosa G, Morelli G
* Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells (261 visite)
Journal Of Drug Targeting (ISSN: 1061-186x), 2012 Nov 21; 21(3): 240-249.
Impact Factor: 2.768
Dettagli Esporta in BibTeX Esporta in EndNote
Campanile F, Maurea S, Mainenti PP, Corvino A, Imbriaco M
* Duodenal Involvement by Breast Cancer (144 visite)
Breast Journal (ISSN: 1075-122x), 2012 Nov; 18(6): 615-616.
Impact Factor: 1.831
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (235 visite)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
Dettagli Esporta in BibTeX Esporta in EndNote
Poletto M, Di Loreto C, Marasco D, Poletto E, Puglisi F, Damante G, Tell G
* Acetylation on critical lysine residues of Apurinic/apyrimidinic endonuclease 1 (APE1) in triple negative breast cancers (256 visite)
Biochemical And Biophysical Research Communications (ISSN: 0006-291x), 2012 Jul 20; 424(1): 34-39.
Impact Factor: 2.406
Dettagli Esporta in BibTeX Esporta in EndNote
Avitabile C, Moggio L, Malgieri G, Capasso D, Di Gaetano S, Saviano M, Pedone C, Romanelli A
* Gamma Sulphate Pna (pna S): Highly Selective Dna Binding Molecule Showing Promising Antigene Activity (257 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2012 May 7; 7(5): e35774-e35774.
Impact Factor: 3.73
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Spoto G
* Artificial DNA and surface plasmon resonance (387 visite)
Artificial Dna Pna & Xna (ISSN: 1949-095x), 2012 Apr; 3(2): N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Avitabile C, Saviano M, D'Andrea LD, Bianchi N, Fabbri E, Brognara E, Gambari R, Romanelli A
* Targeting pre-miRNA by peptide nucleic acids: a new strategy to interfere in the miRNA maturation (307 visite)
Artif Dna Pna Xnaartificial Dna Pna & Xna (ISSN: 1949-9096, 1949-0968, 1949-095x), 2012 Apr; 3(2): 88-96.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Folgiero V, Di Carlo SE, Bossi G, Spugnini E, Di Benedetto A, Bon G, Milella M, Fabi A, Accardo A, Morelli G, Mottolese M, Falcioni R
* Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells (290 visite)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2012; 3(12): N/D-N/D.
Impact Factor: 6.044
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (258 visite)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
Dettagli Esporta in BibTeX Esporta in EndNote
Cantisani M, Vitiello M, Falanga A, Finamore E, Galdiero M, Galdiero S
* Peptides complementary to the active loop of porin P2 from Haemophilus influenzae modulate its activity (326 visite)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1178-2013electronic), 2012; 7: 2361-2371.
Impact Factor: 3.463
Dettagli Esporta in BibTeX Esporta in EndNote
Pacelli R, Conson M, Cella L, Liuzzi R, Solla R, Iorio V, Farella A, Salvatore M
* Prediction Of Relapse And Contralateral Tumor Using Breast Cancer Clinical Variables And Histochemical Subtypes (185 visite)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2012; 103: s246-s246.
Impact Factor: 4.52
Dettagli Esporta in BibTeX Esporta in EndNote
D'Errico G, Ercole C, Lista M, Pizzo E, Falanga A, Galdiero S, Spadaccini R, Picone D
* Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease (285 visite)
Bba-Gen Subjects (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Dec; 1808(12): 3007-3015.
Impact Factor: 3.99
Dettagli Esporta in BibTeX Esporta in EndNote
Tarallo R, Accardo A, Falanga A, Guarnieri D, Vitiello G, Netti P, D'Errico G, Morelli G, Galdiero S
* Clickable functionalization of liposomes with the gH625 peptide from herpes simplex virus type i for intracellular drug delivery (289 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Nov 4; 17(45): 12659-12668.
Impact Factor: 5.925
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis and characterization of a novel ester-based nucleoamino acid for the assembly of aromatic nucleopeptides for biomedical applications (333 visite)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2011 Sep 30; 415(1-2): 206-210.
Impact Factor: 3.35
Dettagli Esporta in BibTeX Esporta in EndNote
Musumeci D, Bucci EM, Roviello GN, Sapio R, Valente M, Moccia M, Bianchi ME, Pedone C
* DNA-based strategies for blocking HMGB1 cytokine activity: Design, synthesis and preliminary in vitro/in vivo assays of DNA and DNA-like duplexes (286 visite)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1742-1752.
Impact Factor: 3.534
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Ricci A, Bucci EM, Pedone C
* Synthesis, biological evaluation and supramolecular assembly of novel analogues of peptidyl nucleosides (628 visite)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1773-1778.
Impact Factor: 3.534
Dettagli Esporta in BibTeX Esporta in EndNote
Terreno E, Boffa C, Menchise V, Fedeli F, Carrera C, Castelli DD, Digilio G, Aime S
* Gadolinium-doped LipoCEST agents: A potential novel class of dual 1H-MRI probes (239 visite)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2011 Apr 28; 47(16): 4667-4669.
Impact Factor: 6.169
Dettagli Esporta in BibTeX Esporta in EndNote
Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (297 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
Dettagli Esporta in BibTeX Esporta in EndNote
Troise F, Monti M, Merlino A, Cozzolino F, Fedele C, Russo Krauss I, Sica F, Pucci P, D'Alessio G, De Lorenzo C
* A novel ErbB2 epitope targeted by human antitumor immunoagents (231 visite)
Febs Journal (ISSN: 1742-464x), 2011 Apr; 278(7): 1156-1166.
Impact Factor: 3.79
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Bucci EM, Pedone C
* Evidences for supramolecular organization of nucleopeptides: Synthesis, spectroscopic and biological studies of a novel dithymine l-serine tetrapeptide (302 visite)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 Apr; 7(4): 1073-1080.
Impact Factor: 3.534
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (294 visite)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Morisco A, Accardo A, Tesauro D, Palumbo R, Benedetti E, Morelli G
* Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (247 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011; 96(1): 88-96.
Impact Factor: 2.87
Dettagli Esporta in BibTeX Esporta in EndNote
Gallucci G, Coccaro M, Storto G, Lapadula L, Tartarone A, Nappi A, Cammarota A, Buonerba C, Di Lorenzo G, Fusco V, Aieta M
* The clinical impact of a cardiologic follow-up in breast cancer survivors: an observational study (183 visite)
Int J Immunopathol Pharmacol (ISSN: 0394-6320), 2010 Oct; 23(4): 1221-1227.
Impact Factor: 2.685
Dettagli Esporta in BibTeX Esporta in EndNote
Pensato S, Saviano M, Bianchi N, Borgatti M, Fabbri E, Gambari R, Romanelli A
* Gamma-Hydroxymethyl Pnas: Synthesis, Interaction With Dna And Inhibition Of Protein/Dna Interactions (231 visite)
Bioorg Chem, 2010 Sep; 38(5): 196-201.
Impact Factor: 2.141
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (260 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
Dettagli Esporta in BibTeX Esporta in EndNote
Avitabile C, Moggio L, D'Andrea LD, Pedone C, Romanelli A
* Development of an efficient and low-cost protocol for the manual PNA synthesis by Fmoc chemistry (243 visite)
Tetrahedron Lett (ISSN: 0040-4039), 2010 Jul 21; 51(29): 3716-3718.
Impact Factor: 2.618
Dettagli Esporta in BibTeX Esporta in EndNote
Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (287 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M
* PET/CT in cancer research: From preclinical to clinical applications (433 visite)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2010 Jul; 5(4): 190-200.
Impact Factor: 4.02
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Iommelli F, Lettieri A, Brunetti A, Salvatore M
* Molecular imaging of tumor microenvironment (307 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2010 Jun; 54(3): 243-258.
Impact Factor: 1.724
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Iommelli F, Lettieri A, Brunetti A, Salvatore M
* Molecular imaging of tumor microenvironment: Challenges and perspectives (398 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2010 Jun; 54(3): 249-258.
Impact Factor: 1.724
Dettagli Esporta in BibTeX Esporta in EndNote
Galdiero S, Falanga A, Vitiello M, Raiola L, Russo L, Pedone C, Isernia C, Galdiero M
* The presence of a single N-terminal histidine residue enhances the fusogenic properties of a Membranotropic peptide derived from herpes simplex virus type 1 glycoprotein (206 visite)
Jbc Papers (ISSN: 1083-351x, 0021-9258, 0021-9258linking), 2010 May 28; 285(22): 17123-17136.
Impact Factor: 5.328
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA (247 visite)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (191 visite)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Impact Factor: 5.361
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Mansi R, Morisco A, Mangiapia G, Paduano L, Tesauro D, Radulescu A, Aurilio M, Aloj L, Arra C, Morelli G
* Peptide modified nanocarriers for selective targeting of bombesin receptors (241 visite)
Mol Biosyst (ISSN: 1742-206x), 2010 May; 6(5): 878-887.
Impact Factor: 3.825
Dettagli Esporta in BibTeX Esporta in EndNote
Pensato S, Renda M, Leccia F, Saviano M, D'Andrea LD, Pedone C, Pedone PV, Romanelli A
* PNA zipper as a dimerization tool: development of a bZip mimic (325 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 May; 93(5): 434-441.
Impact Factor: 2.572
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Gröschel S, Pedone C, Diederichsen U
* Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (226 visite)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2010 May; 38(5): 1301-1309.
Impact Factor: 4.106
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
* Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (246 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 May; 38(5): 1489-1496.
Impact Factor: 4.106
Dettagli Esporta in BibTeX Esporta in EndNote
Conson M, D'Amato G, Nieddu V, Pagliarulo C, Iorio V, Vernieri C, Farella A, Solla R, Cella L, Liuzzi R, Punzo G, Salvatore M, Pacelli R
* Patterns of distant and local relapses in breast cancer patients and triple negative subgroup (192 visite)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 2010 Apr; 51: N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (269 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Pedone C, Bucci EM
* Synthesis, Characterization And Hybridization Studies Of An Alternate Nucleo-Epsilon/Gamma-Peptide: Complexes Formation With Natural Nucleic Acids (256 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jan; 38(1): 103-111.
Impact Factor: 4.106
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Breveglieri G, Zanoli L, Borgatti M, Spoto G, Gambari R
* Surface Plasmon Resonance Imaging (SPR-I), peptide nucleic acid (PNA) probes and nanoparticle-enhancement for PCR-free ultrasensitive detection of beta-thalassemia mutations in human genomic DNA (193 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2010; 26: N/D-N/D.
Impact Factor: 1.814
Dettagli Esporta in BibTeX Esporta in EndNote
Moccia M, Musumeci D, Roviello GN, Fusco S, Valente M, Bucci EM, Sapio R, Pedonea C, Netti PA
* Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks (381 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Oct; 15(10): 647-653.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
Carriero MV, Longanesi-cattani I, Bifulco K, Maglio O, Lista L, Barbieri A, Votta G, Masucci MT, Arra C, Franco R, De Rosa M, Stoppelli MP, Pavone V
* Structure-based design of an urokinase-type plasminogen activator receptor-derived peptide inhibiting cell migration and lung metastasis (281 visite)
Mol Cancer Ther (ISSN: 1535-7163, 1538-8514electronic, 1535-7163linking), 2009 Sep; 8(9): 2708-2717.
Impact Factor: 4.953
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Tesauro D, Aloj L, Pedone C, Morelli G
* Supramolecular aggregates containing lipophilic Gd(III) complexes as contrast agents in MRI (418 visite)
Coord Chem Rev (ISSN: 0010-8545), 2009 Sep; 253(17-18): 2193-2213.
Impact Factor: 11.225
Dettagli Esporta in BibTeX Esporta in EndNote
Imbriaco M, Pisani A, Spinelli L, Cuocolo A, Messalli G, Capuano E, Marmo M, Liuzzi R, Visciano B, Cianciaruso B, Salvatore M
* Effects of enzyme-replacement therapy in patients with Anderson-Fabry disease: a prospective long-term cardiac magnetic resonance imaging study (216 visite)
Heart (ISSN: 1355-6037, 1468-201x), 2009 Jul; 95(13): 1103-1107.
Impact Factor: 5.385
Dettagli Esporta in BibTeX Esporta in EndNote
Storto G, Nicolai E, Salvatore M
* [18F]FDG-PET-CT for early monitoring of tumor response: When and why (260 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009 Apr; 53(2): 167-180.
Impact Factor: 1.724
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Moccia M, Castiglione M, Cesarani A, Bucci EM, Saviano M, Pedone C, Benedetti E
* Evidences Of Complex Formation Between Daba-Based Nucleo-Gamma-Peptides With Alternate Configuration Backbone (282 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 147-154.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
Zaccaro L, Del Gatto A, Pedone C, Saviano M
* Peptides for tumour therapy and diagnosis: current status and future directions (365 visite)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2009 Mar; 16(7): 780-795.
Impact Factor: 4.708
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Castiglione M, Bucci EM, Pedone C, Benedetti E
* Solid Phase Synthesis And Rna-Binding Studies Of A Serum-Resistant Nucleo-Epsilon-Peptide (244 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 155-160.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
Insabato L, Amelio I, Quarto M, Zannetti A, Tolino F, De Mauro G, Cerchia L, Riccio P, Baumhoer D, Condorelli G, Terracciano L, De Franciscis V
* Elevated Expression of the Tyrosine Phosphatase SHP-1 Defines a Subset of High-Grade Breast Tumors (275 visite)
Oncology (ISSN: 0030-2414), 2009; 77(6): 378-384.
Impact Factor: 2.112
Dettagli Esporta in BibTeX Esporta in EndNote
Marasco D, Perretta G, Sabatella M, Ruvo M
* Past and Future Perspectives of Synthetic Peptide Libraries (261 visite)
Curr Protein Pept Sci (ISSN: 1389-2037), 2008 Oct; 9(5): 447-467.
Impact Factor: 3.011
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Bucci EM, Castiglione M, Cesarani A, Pedone C, Piccialli G
* Evidences for complex formation between l-dabPNA and aegPNA (188 visite)
Bioorg Med Chem Lett (ISSN: 0960-894x, 1464-3405, 1464-3405electronic), 2008 Sep 1; 18(17): 4757-4760.
Impact Factor: 2.531
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Grasso G, Marchelli R, Spoto G
* Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (248 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2008 Sep 1; 9(13): 2067-2070.
Impact Factor: 3.322
Dettagli Esporta in BibTeX Esporta in EndNote
Woo LWL, Fischer DS, Sharland CM, Trusselle M, Foster PA, Chander SK, Di Fiore A, Supuran CT, De Simone G, Purohit A, Reed MJ, Potter BVL
* Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography (378 visite)
Mol Cancer Ther (ISSN: 1535-7163, 1538-8514electronic), 2008 Sep; 7(8): 2435-2444.
Impact Factor: 5.003
Dettagli Esporta in BibTeX Esporta in EndNote
Dalla Serra M, Cirioni O, Vitale RM, Renzone G, Coraiola M, Giacometti A, Potrich C, Baroni E, Guella G, Sanseverino M, De Luca S, Scalise G, Amodeo P, Scaloni A
* Structural features of distinctin affecting peptide biological and biochemical properties (295 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2008 Jul 29; 47(30): 7888-7899.
Impact Factor: 3.379
Dettagli Esporta in BibTeX Esporta in EndNote
Sinibaldi F, Fiorucci L, Patriarca A, Lauceri R, Ferri T, Coletta M, Santucci R
* Insights into cytochrome c-cardiolipin interaction. Role played by ionic strength (217 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2008 Jul 1; 47(26): 6928-6935.
Impact Factor: 3.379
Dettagli Esporta in BibTeX Esporta in EndNote
Bifulco K, Longanesi-cattani I, Gargiulo L, Maglio O, Cataldi M, De Rosa M, Stoppelli MP, Pavone V, Carriero MV
* An urokinase receptor antagonist that inhibits cell migration by blocking the formyl peptide receptor (224 visite)
Febs Lett (ISSN: 0014-5793print, 0014-5793linking, 1873-3468electronic), 2008 Apr 2; 582(7): 1141-1146.
Impact Factor: 3.264
Dettagli Esporta in BibTeX Esporta in EndNote
Galdiero S, Vitiello M, D'Isanto M, Falanga A, Cantisani M, Browne H, Pedone C, Galdiero M
* The identification and characterization of fusogenic domains in herpes virus glycoprotein B molecules (262 visite)
Chembiochem (ISSN: 1439-7633, 1439-4227, 1439-7633electronic), 2008 Mar 25; 9(5): 758-767.
Impact Factor: 3.322
Dettagli Esporta in BibTeX Esporta in EndNote
Pensato S, D'Andrea LD, Pedone C, Romanelli A
* New synthetic route to gamma-mercaptomethyl PNA monomers (263 visite)
Synth Commun Synthetic Communications (ISSN: 0039-7911), 2008; 38(15): 2499-2506.
Impact Factor: 0.981
Dettagli Esporta in BibTeX Esporta in EndNote
Breveglieri G, Pensato S, Salvatori F, Saviano M, Pedone C, Romanelli A, Gambari R
* PNA-mediated alteration of mRNA splicing (206 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 175-181.
Impact Factor: 0.1
Dettagli Esporta in BibTeX Esporta in EndNote
Marchelli R, Saviano M, Licandro E, Spoto G, Borgatti M, Gambari R
* PNAs targeting the "RNA world": Micro RNA next? (213 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 183-188.
Impact Factor: 0.1
Dettagli Esporta in BibTeX Esporta in EndNote
Zanoli L, Dagata R, Spoto G
* Surface plasmon-based optical detection of DNA peptide nucleic acids (177 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 165-174.
Impact Factor: 0.1
Dettagli Esporta in BibTeX Esporta in EndNote
Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (239 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
Dettagli Esporta in BibTeX Esporta in EndNote
Pensato S, Saviano M, Romanelli A
* New peptide nucleic acid analogues: synthesis and applications (256 visite)
Expert Opinion On Biological Therapy (ISSN: 1471-2598), 2007 Sep; 7(8): 1219-1232.
Impact Factor: 2.815
Dettagli Esporta in BibTeX Esporta in EndNote
Chambery A, Pisante M, Di Maro A, Di Zazzo E, Ruvo M, Costantini S, Colonna G, Parente A
* Invariant Ser211 is involved in the catalysis of PD-L4, type I RIP from Phytolacca dioica leaves (198 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Apr 1; 67(1): 209-218.
Impact Factor: 3.354
Dettagli Esporta in BibTeX Esporta in EndNote
Cusanno F, Cisbani E, Colilli S, Fratoni R, Garibaldi F, Giuliani F, Gricia M, Lucentini M, Magliozzi ML, Santarivenere F, Torrioli S, Cinti MN, Pani R, Pellegrini R, Simonetti G, Schillaci O, Del Vecchio S, Salvatore M, Majewski S, De Vincentis G, Scopinaro F
* Results of clinical trials with SPEM (190 visite)
Nucl Instrum Methods Phys Res Sect A, 2007 Feb 1; 497(1): 46-50.
Impact Factor: 3.221
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Moccia M, Castiglione M, Sapio R, Valente M, Bucci EM, Perretta G, Pedone C
* Dabpna: Design, Synthesis And Nucleic Acids Binding Studies (270 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(10-12): 1307-1310.
Impact Factor: 0.723
Dettagli Esporta in BibTeX Esporta in EndNote
Moccia M, Musumeci D, Valente M, Roviello GN, Sapio R, Pedone C, Bucci EM
* Thermodynamic studies on PNA and PNA/DNA dendrimer formation (156 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1173-1176.
Impact Factor: 0.723
Dettagli Esporta in BibTeX Esporta in EndNote
Garibaldi F, Cisbani E, Colilli S, Cusanno F, Fratoni R, Giuliani F, Gricia M, Lucentini M, Fratoni R, Lo Meo S, Magliozzi ML, Santanvenere F, Cinti MN, Pani R, Pellegrini R, Simonetti G, Schillaci O, Del Vecchio S, Salvatore M, Majewski S, Lanza RC, De Vincentis G, Scopinaro F
* Molecular imaging: High-resolution detectors for early diagnosis and therapy monitoring of breast cancer (231 visite)
Nucl Instrum Meth A (ISSN: 0168-9002), 2006 Dec 20; 569(2SPEC.ISS.): 286-290.
Impact Factor: 1.185
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (284 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
Dettagli Esporta in BibTeX Esporta in EndNote
Musumeci D, Valente M, Capasso D, Palumbo R, Gorlach M, Schmidtke M, Zell R, Roviello GN, Sapio R, Pedone C, Bucci EM
* A short PNA targeting coxsackievirus B3 5′-nontranslated region prevents virus-induced cytolysis (224 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Mar; 12(3): 161-170.
Impact Factor: 1.801
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Salvatore B, Paone G, Fonti R, Salvatore M
* Functional imaging of multidrug resistance in breast cancer (267 visite)
Phys Med (ISSN: 1120-1797, 1120-1797linking), 2006; 21(SUPPL.1): 24-27.
Impact Factor: 0.313
Dettagli Esporta in BibTeX Esporta in EndNote
Galdiero S, Falanga A, Vitiello M, Browne H, Pedone C, Galdiero M
* Fusogenic domains in herpes simplex virus type 1 glycoprotein (381 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Sep 5; 280(31): 28632-28643.
Impact Factor: 5.854
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Sommella I, Potena A, Salvatore M
* 99mTc-MIBI uptake in Bcl-2 overexpressing breast cancer cells during treatment with gefitinib, a selective tyrosine kinase inhibitor (236 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
Impact Factor: 3.883
Dettagli Esporta in BibTeX Esporta in EndNote
Lauria A, Palmiero R, Forni G, Fantacci ME, Imbriaco M, Sodano A, Indovina PL
* A Study On Two Different Cad Systems For Mmammography As An Aid To Radiological Diagnosis In The Search Of Microcalcification Clusters (200 visite)
Eur J Radiol (ISSN: 0720-048x), 2005; 55(2): 264-269.
Impact Factor: 1.888
Dettagli Esporta in BibTeX Esporta in EndNote
Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R
* Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter (245 visite)
Oncology Research (ISSN: 0965-0407), 2005; 15(7-8): 373-383.
Impact Factor: 1.844
Dettagli Esporta in BibTeX Esporta in EndNote
Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (210 visite)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
Dettagli Esporta in BibTeX Esporta in EndNote
Zannetti A, Del Vecchio S, Fonti R, Iommelli F, Sommella J, Potena A, Salvatore M
* Gefitinib, A Selective, Tyrosine Kinase Inhibitor Increases 99mtc-Mibi Uptake In Bcl-2 Overexpressing Breast Cancer Cells (245 visite)
Mol Immunol, 2005; 4: 355-355.
Impact Factor: 3.003
Dettagli Esporta in BibTeX Esporta in EndNote
Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R
* Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression (258 visite)
Curr Drug Targets (ISSN: 1389-4501), 2004 Nov; 5(8): 735-744.
Impact Factor: 4.104
Dettagli Esporta in BibTeX Esporta in EndNote
Mischiati C, Sereni A, Finotti A, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Pedone C, Borgatti M, Gambari R
* Complexation to cationic microspheres of double-stranded peptide nucleic acid-DNA chimeras exhibiting decoy activity (204 visite)
Journal Of Biomedical Science (ISSN: 1021-7770), 2004 Sep; 11(5): 697-704.
Impact Factor: 1.567
Dettagli Esporta in BibTeX Esporta in EndNote
Penolazzi L, Borgatti M, Lambertini E, Mischiati C, Finotti A, Romanelli A, Saviano M, Pedone C, Piva R, Gambari R
* Peptide nucleic acid-DNA decoy chimeras targeting NF-kappa B transcription factors: Induction of apoptosis in human primary osteoclasts (202 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2004 Sep; 14(2): 145-152.
Impact Factor: 3.19
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Salvatore M
* Tc-99m-MIBI in the evaluation of breast cancer biology (402 visite)
Breast Cancer (ISSN: 9783-540367802), 2004 Jun; 1: 71-81.
Impact Factor: 0.635
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Salvatore M
* Tc-99m-MIBI in the evaluation of breast cancer biology (322 visite) (PDF 139 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Jun; 31(SUPPL.1): S88-S88.
Impact Factor: 3.935
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito G, Vitagliano L, Costanzo P, Borrelli L, Barone R, Pavone L, Izzo P, Zagari A, Salvatore F
* Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function (200 visite)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2004 May 15; 380: 51-56.
Impact Factor: 4.278
Dettagli Esporta in BibTeX Esporta in EndNote
Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C
* Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles (258 visite)
The Aaps Journal (ISSN: 1522-1059, 1550-7416), 2004 Jan 20; 6(1): N/D-N/D.
Impact Factor: 1.938
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Zannetti A, Caracó C, Del Vecchio S, Salvatore M
* Bcl-2 overexpression prevents 99mTc-MIBI uptake in breast cancer cell lines (366 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004; 31(4): 521-527.
Impact Factor: 3.935
Dettagli Esporta in BibTeX Esporta in EndNote
Musumeci D, Roviello GN, Valente M, Sapio R, Pedone C, Bucci EM
* New synthesis of PNA-3′DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras (276 visite)
Biopolymers, 2004; 76(6): 535-542.
Impact Factor: 2.248
Dettagli Esporta in BibTeX Esporta in EndNote
d'Alesio V, Pacelli R, Durante M, Canale Cama G, Cella L, Gialanella G, Grossi G, Pugliese M, Punzo G, Sardi I, Scampoli P, Solla R, Salvatore M
* Lymph nodes in the irradiated field influence the yield of radiation-induced chromosomal aberrations in lymphocytes from breast cancer patients (212 visite)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2003 Nov 1; 57(3): 732-738.
Impact Factor: 4.285
Dettagli Esporta in BibTeX Esporta in EndNote
Menchise V, De Simone G, Tedeschi T, Corradini R, Sforza S, Marchelli R, Capasso D, Saviano M, Pedone C
* Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex (279 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2003 Oct 14; 100(21): 12021-12026.
Impact Factor: 10.272
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (348 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
Dettagli Esporta in BibTeX Esporta in EndNote
Lomax AJ, Cella L, Weber D, Kurtz JM, Miralbell R
* Potential role of IMRT and protons in the treatment of the breast and regional nodes (201 visite)
Int J Rad Oncol Biol Phys, 2003 Mar 1; 48(3Supplement): 785-792.
Impact Factor: 0.155
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Aloj L, Salvatore M
* MIBI as prognostic factor in breast cancer (293 visite)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2003 Mar; 47(1): 46-50.
Impact Factor: 2.222
Dettagli Esporta in BibTeX Esporta in EndNote
Borgatti M, Lampronti I, Romanelli A, Pedone C, Saviano M, Bianchi N, Mischiati C, Gambari R
* Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites (226 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2003 Feb 28; 278(9): 7500-7509.
Impact Factor: 6.482
Dettagli Esporta in BibTeX Esporta in EndNote
Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (340 visite)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
Dettagli Esporta in BibTeX Esporta in EndNote
Lomax AJ, Cella L, Weber D, Kurtz JM, Miralbell R
* Potential role of intensity-modulated photons and protons in the treatment of the breast and regional nodes (188 visite)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2003; 55(3): 785-792.
Impact Factor: 4.285
Dettagli Esporta in BibTeX Esporta in EndNote
Borgatti M, Romanelli A, Saviano M, Pedone C, Lampronti I, Breda L, Nastruzzi C, Bianchi N, Mischiati C, Gambari R
* Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum (177 visite)
Oncology Research (ISSN: 0965-0407), 2003; 13(5): 279-287.
Impact Factor: 1.794
Dettagli Esporta in BibTeX Esporta in EndNote
Gambari R, Borgatti M, Romanelli A, Capasso D, Saviano M, Bianchi N, Lampronti I, Mischiati C, Pedone C
* Transcription factor decoy (TFD) activity of peptide nucleic acids (PNA)-DNA chimeras (148 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2003; 12(Supplement1): N/D-N/D.
Impact Factor: 1.94
Dettagli Esporta in BibTeX Esporta in EndNote
Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R
* Cationic Liposomes As Delivery Systems For Double-Stranded Pna-Dna Chimeras Exhibiting Decoy Activity Against Nf-Kappab Transcription Factors (262 visite)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2002 Sep 15; 64(4): 609-616.
Impact Factor: 3.542
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Caracò C, Fonti R, Botti G, D'Aiuto G, Salvatore M
* Dynamic coupling of Tc-99m-MIBI efflux and apoptotic pathway activation in untreated breast cancer patients (271 visite)
Eur J Nucl Med (ISSN: 1619-7070, 0340-6997, 1619-7089), 2002 Jun; 29(6): 809-814.
Impact Factor: 3.568
Dettagli Esporta in BibTeX Esporta in EndNote
Salvatore M, Fonti R
* New frontiers of nuclear medicine (293 visite)
Tumori (ISSN: 0300-8916, 0300-8916print, 0300-8916linking), 2002 May; 88(3): S60-S60.
Impact Factor: 0.267
Dettagli Esporta in BibTeX Esporta in EndNote
Fonti R, Limite G, Sodano A, Riccardi A, Forestieri P, De Cristofaro G, Pettinato G, Salvatore M
* Sentinel lymph node identification in breast cancer patients (225 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2002 Apr; 103(4): 370-377.
Impact Factor: 1.368
Dettagli Esporta in BibTeX Esporta in EndNote
Menchise V, De Simone G, Corradini R, Sforza S, Sorrentino N, Romanelli A, Saviano M, Pedone C
* Crystallization and preliminary X-ray diffraction studies of a D-lysine-based chiral PNA-DNA duplex (212 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2002 Mar; 58(3): 553-555.
Impact Factor: 1.76
Dettagli Esporta in BibTeX Esporta in EndNote
Zell R, Sidigi K, Bucci E, Stelzner A, Goerlach M
* Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C (258 visite)
Rna (ISSN: 1355-8382), 2002; 8(2): 188-201.
Impact Factor: 5.099
Dettagli Esporta in BibTeX Esporta in EndNote
Danforth Dn JR, Aloj L, Carrasquillo JA, Bacharach SL, Chow C, Zujewski J, Whatley M, Galen B, Merino M, Neumann RD
* The role of 18F-FDG-PET in the local/regional evaluation of women with breast cancer (188 visite)
Breast Cancer Res Tr Kluwer Academic Publishers (ISSN: 0167-6806), 2002; 75(2): 135-146.
Impact Factor: 3.132
Dettagli Esporta in BibTeX Esporta in EndNote
Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions between nuclear factor κB (NF-κB) transcription factors and a PNA-DNA chimera mimicking NF-κB binding sites (216 visite)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 2.849
Dettagli Esporta in BibTeX Esporta in EndNote
Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites (268 visite)
Eur J Biochem (ISSN: 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 4.779
Dettagli Esporta in BibTeX Esporta in EndNote
De Falco S, Ruvoletto MG, Verdoliva A, Ruvo M, Raucci A, Marino M, Senatore S, Cassani G, Alberti A, Pontisso P, Fassina G
* Cloning and Expression of a Novel Hepatitis B Virus-binding Protein from HepG2 Cells (334 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2001 Sep 28; 276(39): 36613-36623.
Impact Factor: 7.258
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Fonti R, Caraco C, Salvatore M
* 99mTc-MIBI uptake and Bcl-2 overexpression in untreated breast cancer patients (235 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Zannetti A, Caraco C, Fonti R, Del Vecchio S, Salvatore M
* 99mTc-MIBI uptake in breast cancer cells during early phases of apoptosis induction with Staurosporine (224 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Del Vecchio S, Zannetti A, Caracò C, Salvatore M
* 99mTc-MIBI uptake is reduced in Bcl-2 overexpressing MCF-7 breast cancer cells (229 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
Dettagli Esporta in BibTeX Esporta in EndNote
Imbriaco M, Del Vecchio S, Riccardi A, Pace L, Di Salle F, Di Gennaro F, Salvatore M, Sodano A
* Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses (257 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2001 Jan; 28(1): 56-63.
Impact Factor: 3.464
Dettagli Esporta in BibTeX Esporta in EndNote
Saviano M, Romanelli A, Bucci E, Pedone C, Mischiati C, Bianchi N, Feriotto G, Borgatti M, Gambari R
Computational procedures to explain the different biological activity of DNA/DNA, DNA/PNA and PNA/PNA hybrid molecules mimicking NF-κB binding sites (338 visite)
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2000 Dec; 18(3): 353-362.
Impact Factor: 1.826
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Ciarmiello A, Zannetti A, Fonti R, Botti G, D'Aiuto G, Salvatore M
Efflux rate of Tc-99m-MIBI and apoptosis in untreated breast cancer patients (228 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2000 May; 41(5): N/D-N/D.
Impact Factor: 3.617
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Del Vecchio S, Damiano M, Borrelli G, Di Gennaro F, Imbriaco M, Panico L, Bifano D, Pettinato G, Salvatore M
Washout of Tc-99m-MIBI and prognostic factors in untreated breast cancer patients (186 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2000 May; 41(5): N/D-N/D.
Impact Factor: 3.617
Dettagli Esporta in BibTeX Esporta in EndNote
Zannetti A, Del Vecchio S, Carriero MV, Fonti R, Franco P, Botti G, D'Aiuto G, Stoppelli MP, Salvatore M
Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma (300 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 2000 Mar 15; 60(6): 1546-1551.
Impact Factor: 8.46
Dettagli Esporta in BibTeX Esporta in EndNote
De Napoli L, De Luca S, Di Fabio G, Messere A, Montesarchio D, Morelli G, Piccialli G, Tesauro D
A facile solid-phase strategy for the synthesis of oligonucleotide- tetraphenylporphyrin conjugates (221 visite)
European Journal Of Organic Chemistry (ISSN: 1434-193x), 2000; (6): 1013-1018.
Impact Factor: 2.15
Dettagli Esporta in BibTeX Esporta in EndNote
Formisano C, Limite G, Lamberti M, Fonti R, Forestieri P
Lymph node mapping and sentinel lymph node biopsy for evaluation of axillary lymph node status in early invasive breast cancer. Our experience (240 visite)
Przegl Lek (ISSN: 0033-2240print, 0033-2240linking), 2000; 57Suppl5: 113-115.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Carriero M, Del Vecchio S, Capozzoli M, Franco P, Fontana L, Zannetti A, Botti G, D'Aiuto G, Salvatore M, Stoppelli M
Urokinase receptor interacts with alpha(v)beta(5) vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer (255 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1999 Oct 15; 59(20): N/D-N/D.
Impact Factor: 8.614
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Del Vecchio S, Damiano M, Zannetti A, Di Gennaro F, Imbriaco M, Salvatore M
Fractional retention of 99mTc-MIBI and proliferation in untreated breast cancer (218 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1999 Sep; 26(9): N/D-N/D.
Impact Factor: 3.239
Dettagli Esporta in BibTeX Esporta in EndNote
Salvatore M, Del Vecchio S
Dynamic imaging: Scintimammography (265 visite)
Eur J Radiol Elsevier Sci Ireland Ltd (ISSN: 0720-048x), 1998 May; 27(SUPPL.2): S259-S259.
Impact Factor: 0.537
Dettagli Esporta in BibTeX Esporta in EndNote
Ciarmiello A, Del Vecchio S, Silvestro P, Potena MI, Carriero MV, Thomas R, Botti G, D'Aiuto G, Salvatore M
Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer (224 visite)
Journal Of Clinical Oncology (ISSN: 0732-183x), 1998 May; 16(5): 1677-1683.
Impact Factor: 8.228
Dettagli Esporta in BibTeX Esporta in EndNote
Mansi L, Rambaldi PF, Cuccurullo V, Pecori B, Quarantelli M, Fallanca F, Del Vecchio E
Diagnostic and prognostic role of 99mTc-Tetrofosmin in breast cancer (167 visite)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1997 Sep; 41(3): 239-250.
Impact Factor: 2.125
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Ciarmiello A, Pace L, Potena MI, Carriero MV, Mainolfi C, Thomas R, D'Aiuto G, Tsuruo T, Salvatore M
Fractional retention of technetium-99m-sestamibi as an index of P- glycoprotein expression in untreated breast cancer patients (232 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Sep; 38(9): 1348-1351.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Cook JA, Krishna MC, Pacelli R, DeGraff W, Liebmann J, Mitchell JB, Russo A, Wink DA
Nitric oxide enhancement of melphalan-induced cytotoxicity (299 visite)
Br J Cancer (ISSN: 0007-0920, 0007-0920print, 0007-0920linking), 1997 Sep; 76(3): 325-334.
Impact Factor: 2.938
Dettagli Esporta in BibTeX Esporta in EndNote
Carriero MV, Del Vecchio S, Franco P, Potena MI, Chiaradonna F, Botti G, Stoppelli MP, Salvatore M
Vitronectin binding to urokinase receptor in human breast cancer (253 visite)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 1997 Sep; 3(8): 1299-1308.
Impact Factor: 3.419
Dettagli Esporta in BibTeX Esporta in EndNote
Lastoria S, Varrella P, Mainolfi C, Piccolo S, Acampa W, Apicella A, Muto P, Thomas R, DAiuto G, Panico R, Salvatore M
Fluorine-18 PET imaging of primary breast cancer: Preliminary results (120 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 May; 38(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Vecchio SD, Ciarmiello A, Potena MI, Carriero MV, Mainolfi C, Botti G, Thomas R, Cerra M, D'Aiuto G, Tsuruo T, Salvatore M
In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients (216 visite)
Eur J Nucl Med (ISSN: 0340-6997print, 0340-6997linking), 1997 Feb; 24(2): 150-159.
Impact Factor: 5.036
Dettagli Esporta in BibTeX Esporta in EndNote
Lastoria S, Varrella P, Thomas R, DAiuto G, Acampa W, Vergara E, Piccolo S, Muto P, Salvatore M
Planning and monitoring the treatment in breast cancer by scintimammography with Tc-99m MIBI (185 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 May; 37(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Costanzo LL, De Guidi G, Giuffrida S, Sortino S, Condorelli G, Pappalardo G
Antioxidant effect of copper(II) on photosensitized lipid peroxidation (399 visite)
J Chem Res (ISSN: 0162-0134print, 0162-0134linking, 1873-3344), 1995 Feb; 57(2): 115-125.
Impact Factor: 1.342
Dettagli Esporta in BibTeX Esporta in EndNote
Varrella P, Lastoria S, Vergara E, Acampa W, Maurea S, Salvatore M
Tc-99m MIBI Scintimammography for monitoring tumor response in patients with advanced breast cancer (132 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Carriero MV, Franco P, Del Vecchio S, Massa O, Botti G, D'Aiuto G, Stoppelli MP, Salvatore M
Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies (281 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1994 Oct 15; 54(20): 5445-5454.
Impact Factor: 8.426
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Stoppelli MP, Carriero MV, Fonti R, Massa O, Li PY, Botti G, Cerra M, D'Aiuto G, Esposito G, Salvatore M
IN-VITRO RECEPTOR IMAGING FOR CHARACTERIZATION OF HUMAN SOLID TUMORS (169 visite)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1994 Jul; 21(5): 771-774.
Impact Factor: 1.042
Dettagli Esporta in BibTeX Esporta in EndNote
Carriero MV, Stoppelli MP, Del Vecchio S, Franco P, Massa O, Fonti R, Salvatore M
Comparative distribution of urokinase receptor and urokinase in human breast cancer (192 visite)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 1994; 35(0): N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Stoppelli MP, Carriere MV, Fonti R, Massa O, Li PY, Botti G, Cerra M, D'Aiuto G, Esposito G, Salvatore M
Human urokinase receptor concentration in malignant and benign breast tumors by in vitro quantitative autoradiography: Comparison with urokinase levels (165 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1993 Jul 1; 53(13): 3198-3206.
Impact Factor: 8.426
Dettagli Esporta in BibTeX Esporta in EndNote
FRITTITTA L, VIGNERI R, PAPA V, GOLDFINE I, GRASSO G, TRISCHITTA V
Structural and functional studies of insulin receptors in human breast cancer (288 visite)
Breast Cancer Res Tr Kluwer Academic Publishers (ISSN: 0167-6806), 1993; 25(1): 73-82.
Impact Factor: 2.43
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Stoppelli P, Fonti R, Carriero MV, Li P, Salvatore M
Urokinase and urokinase receptor overexpression in breast carcinoma as compared to benign lesions (135 visite)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 1993; 34(0): N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
D'Aiuto G, Del Vecchio S, Mansi L, D'Aprile M, Botti G, Salvatore M
Malignant melanoma of the nipple: A case studied with radiolabeled monoclonal antibody (371 visite)
Tumori (ISSN: 0300-8916, 0300-8916print, 0300-8916linking), 1991 Oct 31; 77(5): 449-451.
Impact Factor: 0.408
Dettagli Esporta in BibTeX Esporta in EndNote
Iaffaioli RV, Frasci G, Tortora G, Ciardiello F, Nuzzo F, Scala S, Pacelli R, Bianco AR
Effect of thymic extract 'thymostimulin' on the incidence of infections and myelotoxicity during adjuvant chemotherapy for breast cancer (345 visite)
Thymus (ISSN: 0165-6090), 1988; 12(2): 69-75.
Impact Factor: 0.643
Dettagli Esporta in BibTeX Esporta in EndNote
Alfano B, Coucourde F, Malgieri F, Ragozzino A
PET/CT and radiotherapy (1689 visite)
Q J Nucl Med Mol Imaging, 1980 Oct; 50(1): 4-14.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
196 Records (167 escludendo Abstract e Conferenze).
Impact factor totale: 675.469 (592.709 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 702.103 (595.6 escludendo Abstract e Conferenze).
Impact factor totale: 675.469 (592.709 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 702.103 (595.6 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
Ultima modifica di Marco Comerci in data Thursday 19 March 2015, 12:24:55
347 visite. Ultima visita in data Friday 26 June 2020, 10:23:36
ibb.cnr.it