NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein
CNR Ibb | back to homepage
▲NavBar
Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]


NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (174 visite)

Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R

Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.



Tipo di articolo: Journal Article,

Impact factor: 3.992, Impact factor a 5 anni: 3.307

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0037416495&partnerID=40&md5=edc7651ee12bc9ce74c013343537f1ee

Parole chiave: Dna Recognition, Nmr Spectroscopy, Structure Elucidation, Superman, Zinc Finger Domain, Alpha Amino Acid, Vegetable Protein, Zinc Finger Protein, Amino Acid Sequence, Arabidopsis, Article, Crystal Structure, Dna Binding, Ligand Binding, Nonhuman, Nuclear Magnetic Resonance Spectroscopy, Peptide Synthesis, Plant, Priority Journal, Protein Structure, Reversed Phase High Performance Liquid Chromatography, Structure Analysis, Three Dimensional Imaging, Ultraviolet Spectrophotometry, Arabidopsis Proteins, Dna-Binding Proteins, Molecular Structure, Peptide Biosynthesis, Protein Conformation, Transcription Factors, Animalia, Arabidopsis Thaliana, Embryophyta, Eukaryota,

Affiliazioni:

*** IBB - CNR ***
Dipartimento di Scienze Ambientali, Seconda Universita di Napoli, 81100 Caserta, Italy
Dipartimento di Chimica Biologica, Ist. Biostrutture/Bioimmagini - CNR, Universita di Napoli Federico II, 80134 Napoli, Italy
Bioindustry Park del Canavese, 10010 Colleretto Giacosa, Torino, Italy


Riferimenti:

Berg, J.M., (1995) Acc. Chem. Res., 28, pp. 14-1

Berg, J.M., Godwin, H.A., (1997) Annu. Rev. Biophys. Biomol. Struct., 26, pp. 357-371

Schwabe, J.W.R., Klug, A., (1994) Nat. Struct. Biol., 1, pp. 345-349

Hanas, J.S., Hazuda, D.J., Bogenhagen, D.F., Wu, F.Y.-H., Wu, C.-W., (1983) J. Biol. Chem., 258, pp. 14120-14125

Miller, J., McLachlan, A.D., Klug, A., (1985) EMBO J., 4, pp. 1609-1614

Wolfe, S.A., Nekludova, L., Pabo, C.O., (2000) Annu. Rev. Biophys. Biomol. Struct., 29, pp. 183-212

Foster, M.P., Wuttke, D.S., Radhakrishnan, I., Case, D.A., Gottesfeld, J.M., Wright, P.E., (1997) Nat. Struct. Biol., 4, pp. 605-608

Pedone, P.V., Ghirlando, R., Clore, G.M., Gronenborn, A., Felsenfeld, G., Omichinski, J., (1996) Proc. Natl. Acad. Sci. USA, 93, pp. 2822-2826

Omichinski, J.G., Pedone, P.V., Felsenfeld, G., Gronenborn, A., Clore, G.M., (1997) Nat. Struct. Biol., 4, pp. 122-132

Takatsuji, H., Mori, M., Benfey, P.N., Ren, L., Chua, N.-H., (1992) EMBO J., 71, pp. 241-249

Takatsuji, H., (1999) Plant Mol. Biol., 39, pp. 1073-1078

Kubo, K., Sakamoto, A., Kobuyashi, A., Rybka, Z., Kanno, Y., Nakagawa, H., Nishino, T., Takatsuji, H., (1998) Nucleic Acids Res., 26, pp. 608-616

Sakai, H., Medrano, L.J., Meyerowitz, E.M., (1995) Nature, 378, pp. 199-203

Gerber, H.P., Seipel, K., Georgiev, O., Hofferer, M., Hug, M., Rusconi, S., Schaffner, W., (1994) Science, 263, pp. 808-811

Soeller, W.C., Oh, C.E., Kornberg, T.B., (1993) Mol. Cell. Biol., 13, pp. 7961-7970

Dathan, N., Zaccaro, L., Esposito, S., Isernia, C., Omichinski, J.G., Riccio, A., Pedone, C., Pedone, P.V., (2002) Nucleic Acids Res., 30, pp. 4945-4951

Corpet, F., (1988) Nucleic Acids Res., 16, pp. 10881-10890

Bertini, I., Luchinat, C., (1984) Adv. Inorg. Chem., 6, pp. 71-111

Wisz, M.S., Garrett, C.Z., Hellinga, H.W., (1998) Biochemistry, 37, pp. 8269-8277

Roesijadi, G., Bogumil, R., Vašák, M., Kägi, H.R., (1998) J. Biol. Chem., 273, pp. 17425-17432

Berg, J.M., Merkle, D.L., (1989) J. Am. Chem. Soc., 111, pp. 3759-3761

Wüthrich, K., (1986) NMR of Proteins and Nucleic Acids, , Wiley, New York

Kumar, A., Ernst, R.R., Wüthrich, K., (1980) Biochem. Biophys. Res. Commun., 95, pp. 1-6

Rance, M., Sorensen, O.W., Bodenhausen, G., Wagner, G., Ernst, R.R., Wüthrich, K., (1983) Biochem. Biophys. Res. Commun., 117, pp. 479-485

Griesinger, C., Otting, G., Wüthrich, K., Ernst, R.R., (1988) J. Am. Chem. Soc., 110, pp. 7870-7872

Lee, M.S., Mortishire-Smith, R.J., Wright, P., (1992) FEBS Lett., 309, pp. 29-32

Barbato, G., Cicero, D.O., Bianchi, E., Pessi, A., Bazzo, R., (1996) J. Biomol. NMR, pp. 36-48

Güntert, P., Mumenthaler, C., Wüthrich, K., (1997) J. Mol. Biol., 273, pp. 283-298

Laskowski, R.A., Rullmannn, J.A., MacArthur, M.W., Kaptein, R., Thornton, J.M., (1996) J. Biomol. NMR, 8, pp. 477-486

Laity, J.H., Lee, B.M., Wright, P., (2001) Curr. Opin. Struct. Biol., 11, pp. 39-46

Yoshioka, K., Fukushima, S., Yamazaki, T., Yoshida, M., Takatsuji, H., (2001) J. Biol. Chem., 276, pp. 35802-35807

Pabo, O.C., Peisach, E., Grant, R.A., (2001) Annu. Rev. Biochem., 70, pp. 313-340

Choo, Y., Klug, A., (1997) Curr. Opin. Struct. Biol., 7, pp. 117-125

Takatsuji, H., (1996) Biochem. Biophys. Res. Commun., 224, pp. 219-213

Coste, J., Le-Nguyen, D., Castro, B., (1990) Tethaedron Lett., 31, pp. 201-208

Carpino, L.A., (1993) J. Am. Chem. Soc., 115, pp. 4397-4398

Riddles, P.W., Blakeley, R.L., Zerner, B., (1983) Methods Enzymol., 91, pp. 49-60

Pace, C.N., Vajdos, F., Fee, L., Grimsley, G., Gray, T., (1995) Protein Sci., 4, pp. 2411-2423

Piotto, M., Saudek, V., Sklenár, V., (1992) J. Biomol. NMR, 2, pp. 661-665

Güntert, P., Dötsch, V., Wider, G., (1992) J. Biomol. NMR, 2, pp. 619-629

Bartels, C., Xia, T., Billeter, M., Wüthrich, K., (1995) J. Biomol. NMR, 5, pp. 1-10

Van Gunsteren, W.F., Billeter, S.R., Eising, A.A., Hunenberger, P.H., Kruger, P., Mark, A.E., Scott, W.R.P., Tironi, I.G., (1996) Biomolecular Simulation: The Gromos96 Manual and User Guide, , BIOMOs b.v. Zürich, Groningen, The Netherlands

Arfken, G., (1985) Mathematical Methods for Physicists, pp. 428-436. , Academic Press, Orlando USA

Koradi, R., Billeter, M., Wüthrich, K., (1996) J. Mol. Graphics, 14, pp. 29-32

Fairall, L., Schwabe, J.W.R., Chapman, L., Finch, J.T., Rhodes, D., (1993) Nature, 366, pp. 483-487

Bowres, M.P., Schaufler, L.E., Klevit, R.E., (1999) Nat. Struct. Biol., 6, pp. 478-485

Omichinski, J.G., Clore, G.M., Appella, E., Sakaguchi, K., Gronenborn, A.M., (1990) Biochemistry, 29, pp. 9324-9334

Eirod-Erickson, M., Rould, M.A., Nekludova, L., Pabo, C.O., (1996) Structure, 4, pp. 1171-1180

Lee, M.S., Gippert, G.R., Soman, K.V., Case, D.A., Wright, P.E., (1989) Science, 245, pp. 635-637

Houbaviy, H.B., Husheva, A., Shenk, T., Burley, S.K., (1996) Proc. Natl. Acad. Sci. USA, 93, pp. 13577-13582

Kochoyan, M., Havel, T.F., Nguyen, D.T., Dahl, C.E., Keutmann, H.T., Weiss, M.A., (1991) Biochemistry, 30, pp. 3371-3386

Berg, J. M., (1995) Acc. Chem. Res., 28, pp. 14-1

Berg, J. M., Godwin, H. A., (1997) Annu. Rev. Biophys. Biomol. Struct., 26, pp. 357-371

Schwabe, J. W. R., Klug, A., (1994) Nat. Struct. Biol., 1, pp. 345-349

Hanas, J. S., Hazuda, D. J., Bogenhagen, D. F., Wu, F. Y. -H., Wu, C. -W., (1983) J. Biol. Chem., 258, pp. 14120-14125

Wolfe, S. A., Nekludova, L., Pabo, C. O., (2000) Annu. Rev. Biophys. Biomol. Struct., 29, pp. 183-212

Foster, M. P., Wuttke, D. S., Radhakrishnan, I., Case, D. A., Gottesfeld, J. M., Wright, P. E., (1997) Nat. Struct. Biol., 4, pp. 605-608

Pedone, P. V., Ghirlando, R., Clore, G. M., Gronenborn, A., Felsenfeld, G., Omichinski, J., (1996) Proc. Natl. Acad. Sci. USA, 93, pp. 2822-2826

Omichinski, J. G., Pedone, P. V., Felsenfeld, G., Gronenborn, A., Clore, G. M., (1997) Nat. Struct. Biol., 4, pp. 122-132

Gerber, H. P., Seipel, K., Georgiev, O., Hofferer, M., Hug, M., Rusconi, S., Schaffner, W., (1994) Science, 263, pp. 808-811

Soeller, W. C., Oh, C. E., Kornberg, T. B., (1993) Mol. Cell. Biol., 13, pp. 7961-7970

Wisz, M. S., Garrett, C. Z., Hellinga, H. W., (1998) Biochemistry, 37, pp. 8269-8277

Berg, J. M., Merkle, D. L., (1989) J. Am. Chem. Soc., 111, pp. 3759-3761

W thrich, K., (1986) NMR of Proteins and Nucleic Acids, , Wiley, New York

Lee, M. S., Mortishire-Smith, R. J., Wright, P., (1992) FEBS Lett., 309, pp. 29-32

G ntert, P., Mumenthaler, C., W thrich, K., (1997) J. Mol. Biol., 273, pp. 283-298

Laskowski, R. A., Rullmannn, J. A., MacArthur, M. W., Kaptein, R., Thornton, J. M., (1996) J. Biomol. NMR, 8, pp. 477-486

Laity, J. H., Lee, B. M., Wright, P., (2001) Curr. Opin. Struct. Biol., 11, pp. 39-46

Pabo, O. C., Peisach, E., Grant, R. A., (2001) Annu. Rev. Biochem., 70, pp. 313-340

Carpino, L. A., (1993) J. Am. Chem. Soc., 115, pp. 4397-4398

Riddles, P. W., Blakeley, R. L., Zerner, B., (1983) Methods Enzymol., 91, pp. 49-60

Pace, C. N., Vajdos, F., Fee, L., Grimsley, G., Gray, T., (1995) Protein Sci., 4, pp. 2411-2423

G ntert, P., D tsch, V., Wider, G., (1992) J. Biomol. NMR, 2, pp. 619-629

Van Gunsteren, W. F., Billeter, S. R., Eising, A. A., Hunenberger, P. H., Kruger, P., Mark, A. E., Scott, W. R. P., Tironi, I. G., (1996) Biomolecular Simulation: The Gromos96 Manual and User Guide, , BIOMOs b. v. Z rich, Groningen, The Netherlands

Bowres, M. P., Schaufler, L. E., Klevit, R. E., (1999) Nat. Struct. Biol., 6, pp. 478-485

Omichinski, J. G., Clore, G. M., Appella, E., Sakaguchi, K., Gronenborn, A. M., (1990) Biochemistry, 29, pp. 9324-9334

Lee, M. S., Gippert, G. R., Soman, K. V., Case, D. A., Wright, P. E., (1989) Science, 245, pp. 635-637

Houbaviy, H. B., Husheva, A., Shenk, T., Burley, S. K., (1996) Proc. Natl. Acad. Sci. USA, 93, pp. 13577-13582



Zinc finger domains of the classical type represent the most abundant DNA binding domains in eukaryotic transcription factors. Plant proteins contain from one to four zinc finger domains, which are characterized by high conservation of the sequence QALGGH, shown to be critical for DNA-binding activity The Arabidopsis thaliana SUPERMAN protein, which contains a single QALGGH zinc finger, is necessary for proper spatial development of reproductive floral tissues and has been shown to specifically bind to DNA. Here, we report the synthesis and UV and NMR spectroscopic structural characterization of a 37 amino acid SUPERMAN region complexed to a Zn2+ ion (Zn - SUP37) and present the first high-resolution structure of a classical zinc finger domain from a plant protein. The NMR structure of the SUPERMAN zinc finger domain consists of a very well-defined ββα motif, typical of all other Cys2-His2 zinc fingers structurally characterized. As a consequence, the highly conserved QALGGH sequence is located at the N terminus of the α helix. This region of the domain of animal zinc finger proteins consists of hypervariable residues that are responsible for recognizing the DNA bases. Therefore, we propose a peculiar DNA recognition code for the QALGGH zinc finger domain that includes all or some of the amino acid residues at positions - 1, 2, and 3 (numbered relative to the N terminus of the helix) and possibly others at the C-terminal end of the recognition helix. This study further confirms that the zinc finger domain, though very simple, is an extremely versatile DNA binding motif.
Nessun risultato.
Nessun risultato.

Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]
Vai a fine pagina   Versione per copia e incolla facile   Esporta tutto in BibTeX   Esporta tutto in EndNote


Bocian A, Szymańska M, Brykczyńska D, Kubicki M, Wałęsa-chorab M, Roviello GN, Fik-jaskółka MA, Gorczyński A, Patroniak V
* New artificial biomimetic enzyme analogues based on iron(II/III) Schiff Base complexes: an effect of (benz)imidazole organic moieties on phenoxazinone synthase and DNA recognition (6 visite)
Molecules, 2019 Dec 1; 24: 3173-3173.
Impact Factor: 3.06
Dettagli    Esporta in BibTeX    Esporta in EndNote

Farina B, Del Gatto A, Comegna D, Di Gaetano S, Capasso D, Isernia C, Saviano M, Fattorusso R, Zaccaro L, Russo L
* Conformational studies of RGDechi peptide by natural-abundance NMR spectroscopy (25 visite)
J Pept Sci (ISSN: 1075-2617linking), 2019 May; 25(5): e3166-e3166.
Impact Factor: 1.807
Dettagli    Esporta in BibTeX    Esporta in EndNote

Grage SL, Kara S, Bordessa A, Doan V, Rizzolo F, Putzu M, Kubar T, Papini AM, Chaume G, Brigaud T, Afonin S, Ulrich AS
* Orthogonal (19) F-Labeling for Solid-State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes (118 visite)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Jan 11; N/D: N/D-N/D.
Impact Factor: 5.476
Dettagli    Esporta in BibTeX    Esporta in EndNote

Di Stasi R, Diana D, Capasso D, Di Gaetano S, De Rosa L, Celentano V, Isernia C, Fattorusso R, D'Andrea LD
* VEGFR Recognition Interface of a Proangiogenic VEGF-Mimetic Peptide Determined In Vitro and in the Presence of Endothelial Cells by NMR Spectroscopy (70 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2018; 24(44): 11461-11466.
Impact Factor: 5.16
Dettagli    Esporta in BibTeX    Esporta in EndNote

Calvanese L, Foca A, Sandomenico A, Foca G, Caporale A, Doti N, Iaccarino E, Leonardi A, D'Auria G, Ruvo M, Falcigno L
* Structural insights into the interaction of a monoclonal antibody and Nodal peptides by STD-NMR spectroscopy (202 visite)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391), 2017 Oct 28; N/D: N/D-N/D.
Impact Factor: 2.881
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cavallari E, Carrera C, Aime S, Reineri F
* (13) C MR Hyperpolarization of Lactate by Using ParaHydrogen and Metabolic Transformation in Vitro (44 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017 Jan 23; 23(5): 1200-1204.
Impact Factor: 5.16
Dettagli    Esporta in BibTeX    Esporta in EndNote

Lanza V, Travaglia A, Malgieri G, Fattorusso R, GrassoG, Di Natale G, Zito V, Arena G, Milardi D, Rizzarelli E
* Ubiquitin Associates with the N-Terminal Domain of Nerve Growth Factor: The Role of Copper(II) Ions (118 visite) (PDF 96 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Dec 05; 22(49): 17767-17775.
Impact Factor: 5.317
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Abrosca G, Russo L, Palmieri M, Baglivo I, Netti F, De Paola I, Zaccaro L, Farina B, Iacovino R, Pedone PV, Isernia C, Fattorusso R, Malgieri G
* The (unusual) aspartic acid in the metal coordination sphere of the prokaryotic zinc finger domain (109 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2016 Aug; 161: 91-98.
Impact Factor: 3.348
Dettagli    Esporta in BibTeX    Esporta in EndNote

Celentano V, Diana D, Di Salvo C, De Rosa L, Romanelli A, Fattorusso R, D'Andrea LD
* 1, 2, 3-Triazole Bridge as Conformational Constrain in beta-Hairpin Peptides: Analysis of Hydrogen-Bonded Positions (176 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Apr 11; 22(16): 5534-5537.
Impact Factor: 5.317
Dettagli    Esporta in BibTeX    Esporta in EndNote

Farina B, De Paola I, Russo L, Capasso D, Liguoro A, Gatto AD, Saviano M, Pedone PV, Di Gaetano S, Malgieri G, Zaccaro L, Fattorusso R
* A Combined NMR and Computational Approach to Determine the RGDechi-hCit-alphav beta3 Integrin Recognition Mode in Isolated Cell Membranes (151 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Jan 11; 22(2): 681-693.
Impact Factor: 5.317
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bottini A, Wu B, Barile E, De SK, Leone  M, Pellecchia M
* High-Throughput Screening (HTS) by NMR Guided Identification of Novel Agents Targeting the Protein Docking Domain of YopH (161 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7179linking), 2015 Nov 23; 11(8): 919-927.
Impact Factor: 2.98
Dettagli    Esporta in BibTeX    Esporta in EndNote

Smaldone G, Diana D, Pollegioni L, Di Gaetano S, Fattorusso R, Pedone E
* Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes (166 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print), 2015 Feb 18; 589(7): 798-804.
Impact Factor: 3.519
Dettagli    Esporta in BibTeX    Esporta in EndNote

Diana D, Russomanno A, De Rosa L, Di Stasi R, Capasso D, Di Gaetano S, Romanelli A, Russo L, D'Andrea LD, Fattorusso R
* Functional Binding Surface Of A Beta-Hairpin Vegf Receptor Targeting Peptide Determined By Nmr Spectroscopy In Living Cells (190 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Jan 2; 21(1): 91-95.
Impact Factor: 5.771
Dettagli    Esporta in BibTeX    Esporta in EndNote

Mercurio FA, Di Natale C, Pirone L, Scognamiglio PL, Marasco D, Pedone EM, Saviano M, Leone M
* Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam (201 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633), 2015; 16(11): 1629-1636.
Impact Factor: 2.85
Dettagli    Esporta in BibTeX    Esporta in EndNote

Russo L, Palmieri M, Caso JV, Abrosca GD, Diana D, Malgieri G, Baglivo I, Isernia C, Pedone PV, Fattorusso R
* Towards understanding the molecular recognition process in prokaryotic zinc-finger domain (128 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2015; 91: 100-108.
Impact Factor: 3.902
Dettagli    Esporta in BibTeX    Esporta in EndNote

Vitale RM, Zaccaro L, Di Blasio B, Fattorusso R, Isernia C, Amodeo P, Pedone C, Saviano M
* Conformational features of human melanin-concentrating hormone: an NMR and computational analysis (202 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633), 2014 Sep 17; 4(1): 73-81.
Impact Factor: 3.088
Dettagli    Esporta in BibTeX    Esporta in EndNote

Scognamiglio PL, Di Natale C, Leone M, Poletto M, Vitagliano L, Tell G, Marasco D
* G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection (147 visite)
Bba-Bioenergetics (ISSN: 0005-2728, 0006-3002print), 2014 Jun; 1840(6): 2050-2059.
Impact Factor: 5.353
Dettagli    Esporta in BibTeX    Esporta in EndNote

Palmieri M, Russo L, Malgieri G, Esposito S, Baglivo I, Rivellino A, Farina B, de Paola I, Zaccaro L, Milardi D, Isernia C, Pedone PV, Fattorusso R
* Deciphering the zinc coordination properties of the prokaryotic zinc finger domain: The solution structure characterization of Ros87 H42A functional mutant (161 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2014 Feb; 131: 30-36.
Impact Factor: 3.444
Dettagli    Esporta in BibTeX    Esporta in EndNote

De Rosa L, Diana D, Basile A, Russomanno A, Isernia C, Turco MC, Fattorusso R, D'Andrea LD
* Design, Structural And Biological Characterization Of A Vegf Inhibitor Beta-Hairpin-Constrained Peptide (196 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2014; 73: 210-216.
Impact Factor: 3.447
Dettagli    Esporta in BibTeX    Esporta in EndNote

Malgieri G, Palmieri M, Esposito S, Maione V, Russo L, Baglivo I, De Paola I, Milardi D, Diana D, Zaccaro L, Pedone PV, Fattorusso R, Isernia C
* Zinc To Cadmium Replacement In The Prokaryotic Zinc-Finger Domain (183 visite)
Metallomics (ISSN: 1756-591x, 1756-5901, 1756-591xelectronic), 2013 Dec 18; 6(1): 96-104.
Impact Factor: 3.978
Dettagli    Esporta in BibTeX    Esporta in EndNote

Diana D, Smaldone G, De Antonellis P, Pirone L, Carotenuto M, Alonzi A, Di Gaetano S, Zollo M, Pedone E, Fattorusso R
* Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates (147 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Sep 9; 19(37): 12217-12220.
Impact Factor: 5.696
Dettagli    Esporta in BibTeX    Esporta in EndNote

Farina B, Doti N, Pirone L, Malgieri G, Pedone E, Ruvo M, Fattorusso R
* Molecular basis of the PED/PEA15 interaction with the C-terminal fragment of phospholipase D1 revealed by NMR spectroscopy (200 visite)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Sep; 1834(8): 1572-1580.
Impact Factor: 3.191
Dettagli    Esporta in BibTeX    Esporta in EndNote

Palmieri M, Malgieri G, Russo L, Baglivo I, Esposito S, Netti F, Del Gatto A, De Paola I, Zaccaro L, Pedone PV, Isernia C, Milardi D, Fattorusso R
* Structural Zn(II) Implies a Switch from Fully Cooperative to Partly Downhill Folding in Highly Homologous Proteins (179 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2013 Apr 2; 135(13): 5220-5228.
Impact Factor: 11.444
Dettagli    Esporta in BibTeX    Esporta in EndNote

Mercurio FA, Marasco D, Pirone L, Scognamiglio PL, Pedone E, Pellecchia M, Leone M
* Heterotypic Sam-Sam Association Between Odin-Sam1 And Arap3-Sam: Binding Affinity And Structural Insights (117 visite)
Chembiochem (ISSN: 1439-4227, 1439-9422, 1439-7633), 2013 Jan 2; 14(1): 100-106.
Impact Factor: 2.92
Dettagli    Esporta in BibTeX    Esporta in EndNote

Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (182 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
Dettagli    Esporta in BibTeX    Esporta in EndNote

Tamburino R, Severino V, Sandomenico A, Ruvo M, Parente A, Chambery A, Di Maro A
* De novo sequencing and characterization of a novel Bowman-Birk inhibitor from Lathyrus sativus L. seeds by electrospray mass spectrometry (143 visite)
Mol Biosyst (ISSN: 1742-206x, 1742-2051linking, 1742-2051electronic), 2012 Oct 30; 8(12): 3232-3241.
Impact Factor: 3.35
Dettagli    Esporta in BibTeX    Esporta in EndNote

Di Maro A, Berisio R, Ruggiero A, Tamburino R, Severino V, Zacchia E, Parente A
* Structural and enzymatic properties of an in vivo proteolytic form of PD-S2, type 1 ribosome-inactivating protein from seeds of Phytolacca dioica (126 visite)
Biochem Biophys Res Commun (ISSN: 0006-291x), 2012 May 11; 421(3): 514-520.
Impact Factor: 2.406
Dettagli    Esporta in BibTeX    Esporta in EndNote

Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (165 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cucinotta V, Giuffrida A, Grasso G, MacCarrone G, Mazzaglia A, Messina M, Vecchio G
* Diaminotrehalose-capped β-cyclodextrin, a new member of hemispherodextrins: Synthesis, thermodynamic and spectroscopic characterization and its exploitation in chiral electrokinetic chromatography (126 visite)
J Sep Sci (ISSN: 1615-9306), 2011 Jan; 34(1): 70-76.
Impact Factor: 2.733
Dettagli    Esporta in BibTeX    Esporta in EndNote

Verardi R, Traaseth NJ, Shi L, Porcelli F, Monfregola L, De Luca S, Amodeo P, Veglia G, Scaloni A
* Probing membrane topology of the antimicrobial peptide distinctin by solid-state NMR spectroscopy in zwitterionic and charged lipid bilayers (180 visite)
Bba-Mol Basis Dis (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Jan; 1808(1): 34-40.
Impact Factor: 3.99
Dettagli    Esporta in BibTeX    Esporta in EndNote

Farina B, Pirone L, Russo L, Viparelli F, Doti N, Pedone C, Pedone E, Fattorusso R
* NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites (206 visite)
Febs J (ISSN: 1742-4658, 1742-464x, 1742-4658electronic), 2010 Oct; 277(20): 4229-4240.
Impact Factor: 3.129
Dettagli    Esporta in BibTeX    Esporta in EndNote

Diana D, Ziaco B, Scarabelli G, Pedone C, Colombo G, D'Andrea LD, Fattorusso R
* Structural analysis of a helical peptide unfolding pathway (148 visite)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2010 May 10; 16(18): 5400-5407.
Impact Factor: 5.476
Dettagli    Esporta in BibTeX    Esporta in EndNote

Abbate M, Casella G, Fiore T, Grasso G, Pellerito C, Scopelliti M, Spinella A, Pellerito L
* Structural characterization of triorganotin(IV) complexes with sodium fusidate and DFT calculations (136 visite)
J Organomet Chem (ISSN: 0022-328x), 2010 May 1; 695(9): 1405-1413.
Impact Factor: 2.205
Dettagli    Esporta in BibTeX    Esporta in EndNote

Roviello GN, Gröschel S, Pedone C, Diederichsen U
* Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (136 visite)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2010 May; 38(5): 1301-1309.
Impact Factor: 4.106
Dettagli    Esporta in BibTeX    Esporta in EndNote

Severino V, Chambery A, Di Maro A, Marasco D, Ruggiero A, Berisio R, Giansanti F, Ippoliti R, Parente A
* The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves (116 visite)
Mol Biosyst (ISSN: 1742-206x), 2010; 6(3): 570-579.
Impact Factor: 3.825
Dettagli    Esporta in BibTeX    Esporta in EndNote

Puglisi A, Rizzarelli E, Vecchio G, Iacovino R, Benedetti E, Pedone C, Saviano M
* Crystal And Molecular Structure Of Beta-Cyclodextrins Functionalized With The Anti-Inflammatory Drug Etodolac (188 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1227-1235.
Impact Factor: 2.605
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ruggiero A, Di Maro A, Severino V, Chambery A, Berisio R
* Crystal structure of PD-L1, a ribosome inactivating protein from Phytolacca dioica L. leaves with the property to induce DNA cleavage (172 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1135-1142.
Impact Factor: 2.605
Dettagli    Esporta in BibTeX    Esporta in EndNote

Kaczmarek K, Farina B, Zubrzak P, Jankowski S, Zimecki M, Suder P, Benedetti E, Fattorusso R, Saviano M, Zabrocki J
* Synthesis, conformational analysis and immunological activity of β3Phe-substituted Cyclolinopeptide A analogues (168 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 166-174.
Impact Factor: 1.807
Dettagli    Esporta in BibTeX    Esporta in EndNote

Diana D, Ziaco B, Colombo G, Scarabelli G, Romanelli A, Fedone C, Fattorusso R, D'Andrea LD
* Structural determinants of the unusual helix stability of a de novo engineered vascular endothelial growth factor (VEGF) mimicking peptide (170 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2008; 14(14): 4164-4166.
Impact Factor: 5.454
Dettagli    Esporta in BibTeX    Esporta in EndNote

Costantino V, De Rosa C, Fattorusso E, Imperatore C, Mangoni A, Irace C, Maffettone C, Capasso D, Malorni L, Palumbo R, Pedone C
* Oreacerebrosides: Bioactive cerebrosides with a triunsaturated sphingoid base from the sea star Oreaster reticulatus (117 visite)
Eur J Org Chem (ISSN: 1434-193x), 2007 Nov; (31): 5277-5283.
Impact Factor: 2.914
Dettagli    Esporta in BibTeX    Esporta in EndNote

Malgieri G, Russo L, Esposito S, Baglivo I, Zaccaro L, Pedone EM, Di Blasio B, Isernia C, Pedone PV, Fattorusso R
* The Prokaryotic Cys2his2 Zinc Finger Domain Adopts A Novel Fold As Revealed By The Solution Structure Of Agrobacterium Tumefaciens Ros Dna Binding Domain (140 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2007 Oct 30; 104(44): 17341-17346.
Impact Factor: 9.598
Dettagli    Esporta in BibTeX    Esporta in EndNote

De Pinto V, Tomasello F, Messina A, Guarino F, Benz R, La Mendola D, Magrì A, Milardi D, Pappalardo G
* Determination of the conformation of the human VDAC1 N-terminal peptide, a protein moiety essential for the functional properties of the pore (134 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 7; 8(7): 744-756.
Impact Factor: 3.446
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ruggiero A, Chambery A, Di Maro A, Mastroianni A, Parente A, Berisio R
* Crystallization and preliminary X-ray diffraction analysis of PD-L1, a highly glycosylated ribosome inactivating protein with DNase activity (118 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2007; 14(4): 407-409.
Impact Factor: 1.097
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ruggiero A, Chambery A, Di Maro A, Pisante M, Parente A, Berisio R
* Crystallization and preliminary x-ray diffraction analysis of PD-L4, a ribosome inactivating protein from Phytolacca dioica L. leaves (166 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2007; 14(1): 97-100.
Impact Factor: 1.097
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Messina M, Vecchio G
* High selectivity in new chiral separations of dansyl amino acids by cyclodextrin derivatives in electrokinetic chromatography (144 visite)
J Chromatogr A (ISSN: 0021-9673), 2007; 1155(2): 172-179.
Impact Factor: 3.641
Dettagli    Esporta in BibTeX    Esporta in EndNote

Milardi D, Arnesano F, Grasso G, Magrì A, Tabbì G, Scintilla S, Natile G, Rizzarelli E
* Ubiquitin stability and the Lys63-linked polyubiquitination site are compromised on copper binding (114 visite)
Angew Chem Int Ed (ISSN: 1433-7851, 1521-3773electronic), 2007; 46(42): 7993-7995.
Impact Factor: 10.031
Dettagli    Esporta in BibTeX    Esporta in EndNote

Dalla Bona A, Formaggio F, Peggion C, Kaptein B, Broxterman Quirinus B, Galdiero S, Galdiero M, Vitiello M, Benedetti E, Toniolo C
* Synthesis, conformation, and bioactivity of novel analogues of the antiviral lipopeptide halovir (114 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 748-757.
Impact Factor: 1.801
Dettagli    Esporta in BibTeX    Esporta in EndNote

De Capua A, Goodman M, Amino Y, Saviano M, Benedetti E
* Conformation analysis of aspartame-based sweeteners by NMR spectroscopy, molecular dynamics simulations, and X-ray diffraction studies (265 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2006 Feb; 7(2): 377-387.
Impact Factor: 4.1
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Andrea LD, Iaccarino G, Fattorusso R, Sorriento D, Carannante C, Capasso D, Trimarco B, Pedone C
* Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide (207 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2005 Oct 4; 102(40): 14215-14220.
Impact Factor: 10.231
Dettagli    Esporta in BibTeX    Esporta in EndNote

Falcigno L, Oliva R, D'Auria G, Maletta M, Dettin M, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site 3: Role of site-specific mutations (134 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2004 Dec 3; 5(12): 1653-1661.
Impact Factor: 3.474
Dettagli    Esporta in BibTeX    Esporta in EndNote

Lombardi A, Nastri F, Marasco D, Maglio O, De Sanctis G, Sinibaldi F, Santucci R, Coletta M, Pavone V
* Design of a new mimochrome with unique topology (164 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2003 Nov 21; 9(22): 5643-5654.
Impact Factor: 4.353
Dettagli    Esporta in BibTeX    Esporta in EndNote

Oliva R, Falcigno L, D'Auria G, Dettin M, Scarinci C, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site (123 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Sep 4; 4(8): 727-733.
Impact Factor: 3.992
Dettagli    Esporta in BibTeX    Esporta in EndNote

Oliva R, Falcigno L, D'Auria G, Dettin M, Scarinci C, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site, 2: relevance of an N-terminal helix (93 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Aug 4; 4(8): 727-733.
Impact Factor: 2.92
Dettagli    Esporta in BibTeX    Esporta in EndNote

Dathan N, Zaccaro L, Esposito S, Isernia C, Omichinski JG, Riccio A, Pedone C, Di Blasio B, Fattorusso R, Pedone PV
* The Arabidopsis SUPERMAN protein is able to specifically bind DNA through its single Cys(2)-His(2) zinc finger motif (127 visite)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2002 Nov 15; 30(22): 4945-4951.
Impact Factor: 7.051
Dettagli    Esporta in BibTeX    Esporta in EndNote

Formaggio F, Bonchio M, Crisma M, Peggion C, Mezzato S, Polese A, Barazza A, Antonello S, Maran F, Broxterman QB, Kaptein B, Kamphuis J, Vitale RM, Saviano M, Benedetti E, Toniolo C
* Nitroxyl peptides as catalysts of enantioselective oxidations (190 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2002; 8(1): [d]84-93.
Impact Factor: 4.238
Dettagli    Esporta in BibTeX    Esporta in EndNote

Saviano G, Rossi F, Benedetti E, Pedone C, Mierke DF, Maione A, Zanotti G, Tancredi T, Saviano M
* Structural consequences of metal complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 decapeptides (169 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001 Mar 16; 7(6): 1176-1183.
Impact Factor: 4.614
Dettagli    Esporta in BibTeX    Esporta in EndNote

Zanotti G, Falcigno L, Saviano M, D'Auria G, Bruno BM, Campanile T, Paolillo L
* Solid state and solution conformation of [Ala7]-phalloidin: A synthetic phallotoxin analogue (163 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001; 7(7): 1479-1485.
Impact Factor: 4.614
Dettagli    Esporta in BibTeX    Esporta in EndNote

Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E, Santoro AM
Synthesis, spectroscopic characterisation, and metal ion interaction of a new α-helical peptide (170 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1998; 4(9): 1791-1798.
Impact Factor: 5.153
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Auria G, Maglio O, Nastri F, Lombardi A, Mazzeo M, Morelli G, Paolillo L, Pedone C, Pavone V
Hemoprotein models based on a covalent helix-heme-helix sandwich: 2. Structural characterization of Co(III) mimochrome I Δ and Λ isomers (146 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1997; 3(3): 350-362.
Impact Factor: 4.828
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pavone V, Rossi F, Pucci P, Andini S, Ferrara L, Di Blasio B, Pedone C
Studies on gliadin related peptides. I. Synthesis, purification and 1H n. m. r. characterization of the pentapeptide H-Tyr-(Gln)3-Pro-OH (161 visite)
Int J Pept Protein Res (ISSN: 0367-8377, 0367-8377print), 1983 Oct; 22(4): 482-488.
Impact Factor: 1.255
Dettagli    Esporta in BibTeX    Esporta in EndNote



60 Records (60 escludendo Abstract e Conferenze).
Impact factor totale: 249.349 (249.349 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 255.022 (255.022 escludendo Abstract e Conferenze).







    Esporta in BibTeX    Esporta in EndNote