NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein
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NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (127 visite)

Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R

Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.



Tipo di articolo: Journal Article,

Impact factor: 3.992, Impact factor a 5 anni: 3.307

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0037416495&partnerID=40&md5=edc7651ee12bc9ce74c013343537f1ee

Parole chiave: Dna Recognition, Nmr Spectroscopy, Structure Elucidation, Superman, Zinc Finger Domain, Alpha Amino Acid, Vegetable Protein, Zinc Finger Protein, Amino Acid Sequence, Arabidopsis, Article, Crystal Structure, Dna Binding, Ligand Binding, Nonhuman, Nuclear Magnetic Resonance Spectroscopy, Peptide Synthesis, Plant, Priority Journal, Protein Structure, Reversed Phase High Performance Liquid Chromatography, Structure Analysis, Three Dimensional Imaging, Ultraviolet Spectrophotometry, Arabidopsis Proteins, Dna-Binding Proteins, Molecular Structure, Peptide Biosynthesis, Protein Conformation, Transcription Factors, Animalia, Arabidopsis Thaliana, Embryophyta, Eukaryota,

Affiliazioni:

*** IBB - CNR ***
Dipartimento di Scienze Ambientali, Seconda Universita di Napoli, 81100 Caserta, Italy
Dipartimento di Chimica Biologica, Ist. Biostrutture/Bioimmagini - CNR, Universita di Napoli Federico II, 80134 Napoli, Italy
Bioindustry Park del Canavese, 10010 Colleretto Giacosa, Torino, Italy


Riferimenti:

Berg, J.M., (1995) Acc. Chem. Res., 28, pp. 14-1

Berg, J.M., Godwin, H.A., (1997) Annu. Rev. Biophys. Biomol. Struct., 26, pp. 357-371

Schwabe, J.W.R., Klug, A., (1994) Nat. Struct. Biol., 1, pp. 345-349

Hanas, J.S., Hazuda, D.J., Bogenhagen, D.F., Wu, F.Y.-H., Wu, C.-W., (1983) J. Biol. Chem., 258, pp. 14120-14125

Miller, J., McLachlan, A.D., Klug, A., (1985) EMBO J., 4, pp. 1609-1614

Wolfe, S.A., Nekludova, L., Pabo, C.O., (2000) Annu. Rev. Biophys. Biomol. Struct., 29, pp. 183-212

Foster, M.P., Wuttke, D.S., Radhakrishnan, I., Case, D.A., Gottesfeld, J.M., Wright, P.E., (1997) Nat. Struct. Biol., 4, pp. 605-608

Pedone, P.V., Ghirlando, R., Clore, G.M., Gronenborn, A., Felsenfeld, G., Omichinski, J., (1996) Proc. Natl. Acad. Sci. USA, 93, pp. 2822-2826

Omichinski, J.G., Pedone, P.V., Felsenfeld, G., Gronenborn, A., Clore, G.M., (1997) Nat. Struct. Biol., 4, pp. 122-132

Takatsuji, H., Mori, M., Benfey, P.N., Ren, L., Chua, N.-H., (1992) EMBO J., 71, pp. 241-249

Takatsuji, H., (1999) Plant Mol. Biol., 39, pp. 1073-1078

Kubo, K., Sakamoto, A., Kobuyashi, A., Rybka, Z., Kanno, Y., Nakagawa, H., Nishino, T., Takatsuji, H., (1998) Nucleic Acids Res., 26, pp. 608-616

Sakai, H., Medrano, L.J., Meyerowitz, E.M., (1995) Nature, 378, pp. 199-203

Gerber, H.P., Seipel, K., Georgiev, O., Hofferer, M., Hug, M., Rusconi, S., Schaffner, W., (1994) Science, 263, pp. 808-811

Soeller, W.C., Oh, C.E., Kornberg, T.B., (1993) Mol. Cell. Biol., 13, pp. 7961-7970

Dathan, N., Zaccaro, L., Esposito, S., Isernia, C., Omichinski, J.G., Riccio, A., Pedone, C., Pedone, P.V., (2002) Nucleic Acids Res., 30, pp. 4945-4951

Corpet, F., (1988) Nucleic Acids Res., 16, pp. 10881-10890

Bertini, I., Luchinat, C., (1984) Adv. Inorg. Chem., 6, pp. 71-111

Wisz, M.S., Garrett, C.Z., Hellinga, H.W., (1998) Biochemistry, 37, pp. 8269-8277

Roesijadi, G., Bogumil, R., Vašák, M., Kägi, H.R., (1998) J. Biol. Chem., 273, pp. 17425-17432

Berg, J.M., Merkle, D.L., (1989) J. Am. Chem. Soc., 111, pp. 3759-3761

Wüthrich, K., (1986) NMR of Proteins and Nucleic Acids, , Wiley, New York

Kumar, A., Ernst, R.R., Wüthrich, K., (1980) Biochem. Biophys. Res. Commun., 95, pp. 1-6

Rance, M., Sorensen, O.W., Bodenhausen, G., Wagner, G., Ernst, R.R., Wüthrich, K., (1983) Biochem. Biophys. Res. Commun., 117, pp. 479-485

Griesinger, C., Otting, G., Wüthrich, K., Ernst, R.R., (1988) J. Am. Chem. Soc., 110, pp. 7870-7872

Lee, M.S., Mortishire-Smith, R.J., Wright, P., (1992) FEBS Lett., 309, pp. 29-32

Barbato, G., Cicero, D.O., Bianchi, E., Pessi, A., Bazzo, R., (1996) J. Biomol. NMR, pp. 36-48

Güntert, P., Mumenthaler, C., Wüthrich, K., (1997) J. Mol. Biol., 273, pp. 283-298

Laskowski, R.A., Rullmannn, J.A., MacArthur, M.W., Kaptein, R., Thornton, J.M., (1996) J. Biomol. NMR, 8, pp. 477-486

Laity, J.H., Lee, B.M., Wright, P., (2001) Curr. Opin. Struct. Biol., 11, pp. 39-46

Yoshioka, K., Fukushima, S., Yamazaki, T., Yoshida, M., Takatsuji, H., (2001) J. Biol. Chem., 276, pp. 35802-35807

Pabo, O.C., Peisach, E., Grant, R.A., (2001) Annu. Rev. Biochem., 70, pp. 313-340

Choo, Y., Klug, A., (1997) Curr. Opin. Struct. Biol., 7, pp. 117-125

Takatsuji, H., (1996) Biochem. Biophys. Res. Commun., 224, pp. 219-213

Coste, J., Le-Nguyen, D., Castro, B., (1990) Tethaedron Lett., 31, pp. 201-208

Carpino, L.A., (1993) J. Am. Chem. Soc., 115, pp. 4397-4398

Riddles, P.W., Blakeley, R.L., Zerner, B., (1983) Methods Enzymol., 91, pp. 49-60

Pace, C.N., Vajdos, F., Fee, L., Grimsley, G., Gray, T., (1995) Protein Sci., 4, pp. 2411-2423

Piotto, M., Saudek, V., Sklenár, V., (1992) J. Biomol. NMR, 2, pp. 661-665

Güntert, P., Dötsch, V., Wider, G., (1992) J. Biomol. NMR, 2, pp. 619-629

Bartels, C., Xia, T., Billeter, M., Wüthrich, K., (1995) J. Biomol. NMR, 5, pp. 1-10

Van Gunsteren, W.F., Billeter, S.R., Eising, A.A., Hunenberger, P.H., Kruger, P., Mark, A.E., Scott, W.R.P., Tironi, I.G., (1996) Biomolecular Simulation: The Gromos96 Manual and User Guide, , BIOMOs b.v. Zürich, Groningen, The Netherlands

Arfken, G., (1985) Mathematical Methods for Physicists, pp. 428-436. , Academic Press, Orlando USA

Koradi, R., Billeter, M., Wüthrich, K., (1996) J. Mol. Graphics, 14, pp. 29-32

Fairall, L., Schwabe, J.W.R., Chapman, L., Finch, J.T., Rhodes, D., (1993) Nature, 366, pp. 483-487

Bowres, M.P., Schaufler, L.E., Klevit, R.E., (1999) Nat. Struct. Biol., 6, pp. 478-485

Omichinski, J.G., Clore, G.M., Appella, E., Sakaguchi, K., Gronenborn, A.M., (1990) Biochemistry, 29, pp. 9324-9334

Eirod-Erickson, M., Rould, M.A., Nekludova, L., Pabo, C.O., (1996) Structure, 4, pp. 1171-1180

Lee, M.S., Gippert, G.R., Soman, K.V., Case, D.A., Wright, P.E., (1989) Science, 245, pp. 635-637

Houbaviy, H.B., Husheva, A., Shenk, T., Burley, S.K., (1996) Proc. Natl. Acad. Sci. USA, 93, pp. 13577-13582

Kochoyan, M., Havel, T.F., Nguyen, D.T., Dahl, C.E., Keutmann, H.T., Weiss, M.A., (1991) Biochemistry, 30, pp. 3371-3386

Berg, J. M., (1995) Acc. Chem. Res., 28, pp. 14-1

Berg, J. M., Godwin, H. A., (1997) Annu. Rev. Biophys. Biomol. Struct., 26, pp. 357-371

Schwabe, J. W. R., Klug, A., (1994) Nat. Struct. Biol., 1, pp. 345-349

Hanas, J. S., Hazuda, D. J., Bogenhagen, D. F., Wu, F. Y. -H., Wu, C. -W., (1983) J. Biol. Chem., 258, pp. 14120-14125

Wolfe, S. A., Nekludova, L., Pabo, C. O., (2000) Annu. Rev. Biophys. Biomol. Struct., 29, pp. 183-212

Foster, M. P., Wuttke, D. S., Radhakrishnan, I., Case, D. A., Gottesfeld, J. M., Wright, P. E., (1997) Nat. Struct. Biol., 4, pp. 605-608

Pedone, P. V., Ghirlando, R., Clore, G. M., Gronenborn, A., Felsenfeld, G., Omichinski, J., (1996) Proc. Natl. Acad. Sci. USA, 93, pp. 2822-2826

Omichinski, J. G., Pedone, P. V., Felsenfeld, G., Gronenborn, A., Clore, G. M., (1997) Nat. Struct. Biol., 4, pp. 122-132

Gerber, H. P., Seipel, K., Georgiev, O., Hofferer, M., Hug, M., Rusconi, S., Schaffner, W., (1994) Science, 263, pp. 808-811

Soeller, W. C., Oh, C. E., Kornberg, T. B., (1993) Mol. Cell. Biol., 13, pp. 7961-7970

Wisz, M. S., Garrett, C. Z., Hellinga, H. W., (1998) Biochemistry, 37, pp. 8269-8277

Berg, J. M., Merkle, D. L., (1989) J. Am. Chem. Soc., 111, pp. 3759-3761

W thrich, K., (1986) NMR of Proteins and Nucleic Acids, , Wiley, New York

Lee, M. S., Mortishire-Smith, R. J., Wright, P., (1992) FEBS Lett., 309, pp. 29-32

G ntert, P., Mumenthaler, C., W thrich, K., (1997) J. Mol. Biol., 273, pp. 283-298

Laskowski, R. A., Rullmannn, J. A., MacArthur, M. W., Kaptein, R., Thornton, J. M., (1996) J. Biomol. NMR, 8, pp. 477-486

Laity, J. H., Lee, B. M., Wright, P., (2001) Curr. Opin. Struct. Biol., 11, pp. 39-46

Pabo, O. C., Peisach, E., Grant, R. A., (2001) Annu. Rev. Biochem., 70, pp. 313-340

Carpino, L. A., (1993) J. Am. Chem. Soc., 115, pp. 4397-4398

Riddles, P. W., Blakeley, R. L., Zerner, B., (1983) Methods Enzymol., 91, pp. 49-60

Pace, C. N., Vajdos, F., Fee, L., Grimsley, G., Gray, T., (1995) Protein Sci., 4, pp. 2411-2423

G ntert, P., D tsch, V., Wider, G., (1992) J. Biomol. NMR, 2, pp. 619-629

Van Gunsteren, W. F., Billeter, S. R., Eising, A. A., Hunenberger, P. H., Kruger, P., Mark, A. E., Scott, W. R. P., Tironi, I. G., (1996) Biomolecular Simulation: The Gromos96 Manual and User Guide, , BIOMOs b. v. Z rich, Groningen, The Netherlands

Bowres, M. P., Schaufler, L. E., Klevit, R. E., (1999) Nat. Struct. Biol., 6, pp. 478-485

Omichinski, J. G., Clore, G. M., Appella, E., Sakaguchi, K., Gronenborn, A. M., (1990) Biochemistry, 29, pp. 9324-9334

Lee, M. S., Gippert, G. R., Soman, K. V., Case, D. A., Wright, P. E., (1989) Science, 245, pp. 635-637

Houbaviy, H. B., Husheva, A., Shenk, T., Burley, S. K., (1996) Proc. Natl. Acad. Sci. USA, 93, pp. 13577-13582



Zinc finger domains of the classical type represent the most abundant DNA binding domains in eukaryotic transcription factors. Plant proteins contain from one to four zinc finger domains, which are characterized by high conservation of the sequence QALGGH, shown to be critical for DNA-binding activity The Arabidopsis thaliana SUPERMAN protein, which contains a single QALGGH zinc finger, is necessary for proper spatial development of reproductive floral tissues and has been shown to specifically bind to DNA. Here, we report the synthesis and UV and NMR spectroscopic structural characterization of a 37 amino acid SUPERMAN region complexed to a Zn2+ ion (Zn - SUP37) and present the first high-resolution structure of a classical zinc finger domain from a plant protein. The NMR structure of the SUPERMAN zinc finger domain consists of a very well-defined ββα motif, typical of all other Cys2-His2 zinc fingers structurally characterized. As a consequence, the highly conserved QALGGH sequence is located at the N terminus of the α helix. This region of the domain of animal zinc finger proteins consists of hypervariable residues that are responsible for recognizing the DNA bases. Therefore, we propose a peculiar DNA recognition code for the QALGGH zinc finger domain that includes all or some of the amino acid residues at positions - 1, 2, and 3 (numbered relative to the N terminus of the helix) and possibly others at the C-terminal end of the recognition helix. This study further confirms that the zinc finger domain, though very simple, is an extremely versatile DNA binding motif.
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Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (120 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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Cucinotta V, Giuffrida A, Grasso G, MacCarrone G, Mazzaglia A, Messina M, Vecchio G
* Diaminotrehalose-capped β-cyclodextrin, a new member of hemispherodextrins: Synthesis, thermodynamic and spectroscopic characterization and its exploitation in chiral electrokinetic chromatography (110 visite)
J Sep Sci (ISSN: 1615-9306), 2011 Jan; 34(1): 70-76.
Impact Factor: 2.733
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Verardi R, Traaseth NJ, Shi L, Porcelli F, Monfregola L, De Luca S, Amodeo P, Veglia G, Scaloni A
* Probing membrane topology of the antimicrobial peptide distinctin by solid-state NMR spectroscopy in zwitterionic and charged lipid bilayers (126 visite)
Biochim Biophys Acta (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Jan; 1808(1): 34-40.
Impact Factor: 3.99
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Farina B, Pirone L, Russo L, Viparelli F, Doti N, Pedone C, Pedone E, Fattorusso R
* NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites (138 visite)
Febs J (ISSN: 1742-4658, 1742-464x, 1742-4658electronic), 2010 Oct; 277(20): 4229-4240.
Impact Factor: 3.129
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Diana D, Ziaco B, Scarabelli G, Pedone C, Colombo G, D'Andrea LD, Fattorusso R
* Structural analysis of a helical peptide unfolding pathway (137 visite)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2010 May 10; 16(18): 5400-5407.
Impact Factor: 5.476
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Abbate M, Casella G, Fiore T, Grasso G, Pellerito C, Scopelliti M, Spinella A, Pellerito L
* Structural characterization of triorganotin(IV) complexes with sodium fusidate and DFT calculations (117 visite)
J Organomet Chem (ISSN: 0022-328x), 2010 May 1; 695(9): 1405-1413.
Impact Factor: 2.205
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Roviello GN, Gröschel S, Pedone C, Diederichsen U
* Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (108 visite)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2010 May; 38(5): 1301-1309.
Impact Factor: 4.106
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Severino V, Chambery A, Di Maro A, Marasco D, Ruggiero A, Berisio R, Giansanti F, Ippoliti R, Parente A
* The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves (100 visite)
Mol Biosyst (ISSN: 1742-206x), 2010; 6(3): 570-579.
Impact Factor: 3.825
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Puglisi A, Rizzarelli E, Vecchio G, Iacovino R, Benedetti E, Pedone C, Saviano M
* Crystal And Molecular Structure Of Beta-Cyclodextrins Functionalized With The Anti-Inflammatory Drug Etodolac (144 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1227-1235.
Impact Factor: 2.605
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Ruggiero A, Di Maro A, Severino V, Chambery A, Berisio R
* Crystal structure of PD-L1, a ribosome inactivating protein from Phytolacca dioica L. leaves with the property to induce DNA cleavage (126 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1135-1142.
Impact Factor: 2.605
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Kaczmarek K, Farina B, Zubrzak P, Jankowski S, Zimecki M, Suder P, Benedetti E, Fattorusso R, Saviano M, Zabrocki J
* Synthesis, conformational analysis and immunological activity of β3Phe-substituted Cyclolinopeptide A analogues (127 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 166-174.
Impact Factor: 1.807
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Diana D, Ziaco B, Colombo G, Scarabelli G, Romanelli A, Fedone C, Fattorusso R, D'Andrea LD
* Structural determinants of the unusual helix stability of a de novo engineered vascular endothelial growth factor (VEGF) mimicking peptide (125 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2008; 14(14): 4164-4166.
Impact Factor: 5.454
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Costantino V, De Rosa C, Fattorusso E, Imperatore C, Mangoni A, Irace C, Maffettone C, Capasso D, Malorni L, Palumbo R, Pedone C
* Oreacerebrosides: Bioactive cerebrosides with a triunsaturated sphingoid base from the sea star Oreaster reticulatus (101 visite)
Eur J Org Chem (ISSN: 1434-193x), 2007 Nov; (31): 5277-5283.
Impact Factor: 2.914
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Malgieri G, Russo L, Esposito S, Baglivo I, Zaccaro L, Pedone EM, Di Blasio B, Isernia C, Pedone PV, Fattorusso R
* The Prokaryotic Cys2his2 Zinc Finger Domain Adopts A Novel Fold As Revealed By The Solution Structure Of Agrobacterium Tumefaciens Ros Dna Binding Domain (96 visite)
Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2007 Oct 30; 104(44): 17341-17346.
Impact Factor: 9.598
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De Pinto V, Tomasello F, Messina A, Guarino F, Benz R, La Mendola D, Magrì A, Milardi D, Pappalardo G
* Determination of the conformation of the human VDAC1 N-terminal peptide, a protein moiety essential for the functional properties of the pore (109 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 7; 8(7): 744-756.
Impact Factor: 3.446
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Ruggiero A, Chambery A, Di Maro A, Mastroianni A, Parente A, Berisio R
* Crystallization and preliminary X-ray diffraction analysis of PD-L1, a highly glycosylated ribosome inactivating protein with DNase activity (104 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2007; 14(4): 407-409.
Impact Factor: 1.097
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Ruggiero A, Chambery A, Di Maro A, Pisante M, Parente A, Berisio R
* Crystallization and preliminary x-ray diffraction analysis of PD-L4, a ribosome inactivating protein from Phytolacca dioica L. leaves (146 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2007; 14(1): 97-100.
Impact Factor: 1.097
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Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Messina M, Vecchio G
* High selectivity in new chiral separations of dansyl amino acids by cyclodextrin derivatives in electrokinetic chromatography (123 visite)
J Chromatogr A (ISSN: 0021-9673), 2007; 1155(2): 172-179.
Impact Factor: 3.641
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Milardi D, Arnesano F, Grasso G, Magrì A, Tabbì G, Scintilla S, Natile G, Rizzarelli E
* Ubiquitin stability and the Lys63-linked polyubiquitination site are compromised on copper binding (100 visite)
Angew Chem Int Ed (ISSN: 1433-7851, 1521-3773electronic), 2007; 46(42): 7993-7995.
Impact Factor: 10.031
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Dalla Bona A, Formaggio F, Peggion C, Kaptein B, Broxterman Quirinus B, Galdiero S, Galdiero M, Vitiello M, Benedetti E, Toniolo C
* Synthesis, conformation, and bioactivity of novel analogues of the antiviral lipopeptide halovir (100 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 748-757.
Impact Factor: 1.801
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De Capua A, Goodman M, Amino Y, Saviano M, Benedetti E
* Conformation analysis of aspartame-based sweeteners by NMR spectroscopy, molecular dynamics simulations, and X-ray diffraction studies (200 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2006 Feb; 7(2): 377-387.
Impact Factor: 4.1
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D'Andrea LD, Iaccarino G, Fattorusso R, Sorriento D, Carannante C, Capasso D, Trimarco B, Pedone C
* Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide (149 visite)
Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2005 Oct 4; 102(40): 14215-14220.
Impact Factor: 10.231
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Falcigno L, Oliva R, D'Auria G, Maletta M, Dettin M, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site 3: Role of site-specific mutations (111 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2004 Dec 3; 5(12): 1653-1661.
Impact Factor: 3.474
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Lombardi A, Nastri F, Marasco D, Maglio O, De Sanctis G, Sinibaldi F, Santucci R, Coletta M, Pavone V
* Design of a new mimochrome with unique topology (111 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2003 Nov 21; 9(22): 5643-5654.
Impact Factor: 4.353
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Oliva R, Falcigno L, D'Auria G, Dettin M, Scarinci C, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site (111 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Sep 4; 4(8): 727-733.
Impact Factor: 3.992
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Oliva R, Falcigno L, D'Auria G, Dettin M, Scarinci C, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site, 2: relevance of an N-terminal helix (81 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Aug 4; 4(8): 727-733.
Impact Factor: 2.92
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Dathan N, Zaccaro L, Esposito S, Isernia C, Omichinski JG, Riccio A, Pedone C, Di Blasio B, Fattorusso R, Pedone PV
* The Arabidopsis SUPERMAN protein is able to specifically bind DNA through its single Cys(2)-His(2) zinc finger motif (84 visite)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2002 Nov 15; 30(22): 4945-4951.
Impact Factor: 7.051
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Formaggio F, Bonchio M, Crisma M, Peggion C, Mezzato S, Polese A, Barazza A, Antonello S, Maran F, Broxterman QB, Kaptein B, Kamphuis J, Vitale RM, Saviano M, Benedetti E, Toniolo C
* Nitroxyl peptides as catalysts of enantioselective oxidations (143 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2002; 8(1): [d]84-93.
Impact Factor: 4.238
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Saviano G, Rossi F, Benedetti E, Pedone C, Mierke DF, Maione A, Zanotti G, Tancredi T, Saviano M
* Structural consequences of metal complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 decapeptides (122 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001 Mar 16; 7(6): 1176-1183.
Impact Factor: 4.614
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Zanotti G, Falcigno L, Saviano M, D'Auria G, Bruno BM, Campanile T, Paolillo L
* Solid state and solution conformation of [Ala7]-phalloidin: A synthetic phallotoxin analogue (111 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001; 7(7): 1479-1485.
Impact Factor: 4.614
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Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E, Santoro AM
Synthesis, spectroscopic characterisation, and metal ion interaction of a new α-helical peptide (124 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1998; 4(9): 1791-1798.
Impact Factor: 5.153
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D'Auria G, Maglio O, Nastri F, Lombardi A, Mazzeo M, Morelli G, Paolillo L, Pedone C, Pavone V
Hemoprotein models based on a covalent helix-heme-helix sandwich: 2. Structural characterization of Co(III) mimochrome I Δ and Λ isomers (123 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1997; 3(3): 350-362.
Impact Factor: 4.828
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Pavone V, Rossi F, Pucci P, Andini S, Ferrara L, Di Blasio B, Pedone C
Studies on gliadin related peptides. I. Synthesis, purification and 1H n. m. r. characterization of the pentapeptide H-Tyr-(Gln)3-Pro-OH (121 visite)
Int J Pept Protein Res (ISSN: 0367-8377, 0367-8377print), 1983 Oct; 22(4): 482-488.
Impact Factor: 1.255
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58 Records (58 escludendo Abstract e Conferenze).
Impact factor totale: 244.482 (244.482 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 249.77 (249.77 escludendo Abstract e Conferenze).







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