Tc-99m tetrofosmin tomography after nitrate administration in patients with ischemic left ventricular dysfunction: Relation to metabolic imaging by PET
Tc-99m tetrofosmin tomography after nitrate administration in patients with ischemic left ventricular dysfunction: Relation to metabolic imaging by PET(146 visite) He W, Acampa W, Mainolfi C, Menna F, Sorrentino AR, Petretta M, Cuocolo A
*** IBB - CNR *** Dept. Biomorphol. Functional Sci., Institute of Internal Medicine, Univeristy Federico II, Via Pansini 5, 80131 Napoli, Italy University of Federico II, Inst. of Biostructure and Bioimages, National Council of Research, Via Pansini 5, 80131 Napoli, Italy IRCCS Neuromed, Pozzilli, Italy Inst. Int. Med. Cardiol./Heart Surg., University Federico II, Via Pansini 5, 80131 Napoli, Italy
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Patterson, R. E., Pilcher, W. C., Assessing myocardial viability to help select patients for revascularization to improve left ventricular dysfunction due to coronary artery disease (1995) Semin. Thorac. Cardiovasc. Surg., 7, pp. 214-22
Marwick, T. H., Zuchowski, C., Lauer, M. S., Functional status and quality of life in patients with heart failure undergoing coronary bypass surgery after assessment of myocardial viability (1999) J. Am. Coll. Cardiol., 33, pp. 750-758
Paeng, J. C., Lee, D. S., Cheon, G. J., Consideration of perfusion reserve in viability assessment by myocardial Tl-201 rest-redistribution SPECT: A quantitative study with dual-isotope SPECT (2002) J. Nucl. Cardiol., 9, pp. 68-74
Saha, G. B., MacIntyre, W. J., Brunken, R. C., Present assessment of myocardial viability by nuclear imaging (1996) Semin. Nucl. Med., 26, pp. 315-335
Bonow, R. O., Dilsizian, V., Cuocolo, A., Bacharach, S., Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction. Comparison of thallium scintigraphy with reinjection and PET imaging with 18F-fluorodeoxyglucose (1991) Circulation, 83, pp. 26-37
Udelson, J. E., Coleman, P. S., Metherall, J., Predicting recovery of severe regional ventricular dysfunction: Comparison of resting scintigraphy with 201-thallium and 99mTc-sestamibi (1994) Circulation, 89, pp. 2552-2561
Sciagr, R., Leoncini, M., Marcucci, G., Dabizzi, R. P., Pupi, A., Technetium-99m sestamibi imaging to predict left ventricular ejection fraction outcome after revascularization in patients with chronic coronary artery disease and left ventricular dysfunction: Comparison between baseline and nitrate enhanced imaging (2001) Eur. J. Nucl. Med., 28, pp. 680-687
Fleiss, J. L., Statistical methods for rates and proportions (1981), pp. 217-225. , New York: Wiley and SonsBaer, F. M., Erdmann, E., Methods of assessment and clinical relevance of myocardial hibernation and stunning. Assessment of myocardial viability (1998) Thorac. Cardiovasc. Surg., 46 (SUPPL. 2), pp. 264-269
He, Z. W., Verani, M. S., Liu, X. J., Nitrate-augmented myocardial imaging for assessment of myocardial viability (1995) J. Nucl. Cardiol., 2, pp. 352-357
Oudiz, R. J., Smith, D. E., Pollak, A. J., Nitrate-enhanced thallium 201 single-photon emission computed tomography imaging in hibernating myocardium (1999) Am. Heart J., 138, pp. 369-375
Wadhwa, S. S., Mansberg, R., Fernandes, V. B., Tl-201 myocardial perfusion SPECT: Role of nitrate-augmented redistribution (1999) Clin. Nucl. Med., 24, pp. 1-5
Thorley, P. J., Sheard, K. L., Wright, D. J., Sivananthan, U. M., The routine use of sublingual GTN with resting 99m-Tc-tetrofosmin myocardial perfusion imaging (1998) Nucl. Med. Commun., 19, pp. 937-942
Brown, B. G., Bolson, E., Peterson, R. B., Pierce, C. D., Dodge, H. T., The mechanisms of nitroglycerin action: Stenosis vasodilation as a major component of the drug response (1981) Circulation, 64, pp. 1089-1097
He, Z. X., Medrano, R., Hays, J. T., Mahmarian, J. J., Verani, M. S., Nitroglycerin-augmented Tl-201 reinjection enhances detection of reversible myocardial hypoperfusion. A randomized, double-blind, parallel, placebo-controlled trial (1997) Circulation, 95, pp. 1799-1805
Cohn, P. F., Maddox, D., Holman, B. L., Effect of sublingually administered nitroglycerin on regional myocardial blood flow in patients with coronary artery disease (1977) Am. J. Cardiol., 39, pp. 672-678
Fallen, E. L., Nahmias, C., Scheffel, A., Redistribution of myocardial blood flow with topical nitroglycerin in patients with coronary artery disease (1995) Circulation, 91, pp. 1381-1388
Mahmarian, J. J., Fenimore, N. L., Marks, G. F., Transdermal nitroglycerin patch therapy reduces the extent of exercise-induced myocardial ischemia: Results of a double-blind, placebo-controlled trial using quantitative thallium-201 tomography (1994) J. Am. Coll. Cardiol., 24, pp. 25-32
He, Z. X., Kou, R. W., Liu, X. J., Measurements of the effects of percutaneous nitroglycerin on left ventricular performance in patients with coronary artery disease with a cardiac probe (1988) Eur. J. Nucl. Med., 14, pp. 374-377
Background. In patients with ischemic left ventricular (LV) dysfunction, myocardial perfusion imaging after nitrate administration may improve the identification of dysfunctional but viable myocardium. This study was designed to assess the relationship between tetrofosmin uptake after nitrate administration and metabolic activity as assessed by positron emission tomography (PET) in patients with ischemic LV dysfunction. Methods and Results. Thirty-six patients with chronic myocardial infarction and LV dysfunction (ejection fraction, 35% ± 6%) underwent resting technetium 99m tetrofosmin single photon emission computed tomography (SPECT) imaging under control conditions (baseline) and after sublingual administration of 10 mg isosorbide dinitrate. Within 1 week, all patients underwent metabolic PET imaging with fluorine 18-fluorodeoxyglucose. Tetrofosmin uptake and metabolic activity were measured in 13 segments/patient. Regional LV function was assessed in corresponding segments by echocardiography. On baseline tetrofosmin imaging, 53 (40%) of the 131 akinetic or dyskinetic segments had reduced (
132 Records (111 escludendo Abstract e Conferenze). Impact factor totale: 383.154 (307.892 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 444.569 (351.832 escludendo Abstract e Conferenze).
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