The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity: Mechanism and regulation (459 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2002 Dec 27; 277(52): 50348-50354.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 6.696, 5-year impact factor: 4.863
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0347297582&partnerID=40&md5=2d7814af3182f86e498c841a7a2117ab
Keywords: Cytology, Hydrolysis, Immunology, Neurology, Nitric Acid, Proteins, Synthesis (chemical), Toxicity, Glioma Cells, 2 Methyl 3 (1 Naphthoyl) 1 Propylindole, 3 Dihydro 5 Methyl 3 (morpholinomethyl) 6 (1 Naphthoyl)pyrrolo[1, 3 De][1, 4]benzoxazine, 5 (4 Chloro 3 Methylphenyl) 1 (4 Methylbenzyl) N (1, 3 Trimethylbicyclo[2 2 1]heptan 2 Yl) 3 Pyrazolecarboxamide, Anandamide, Arginine, Cannabinoid, Cannabinoid 1 Receptor, Cannabinoid 2 Receptor, Cannabinoid Receptor Agonist, Gamma Interferon, Nitric Oxide Synthase, Rimonabant, Transactivator Protein, Animal Cell, Article, Controlled Study, Cytotoxicity, Drug Effect, Drug Inhibition, Human Immunodeficiency Virus 1, Nonhuman, Priority Journal, Protection, Protein Expression, Bornanes, Cell Survival, Endocannabinoids, Gene Expression Regulation, Enzymologic, Neoplastic, Gene Products, Hiv-1, Naphthalenes, Nitric Oxide Donors, Nitric Oxide Synthase Type Ii, Peptide Fragments, Reverse Transcriptase Polymerase Chain Reaction, Tumor Cells, Cultured, 3 Dihydro 5 Methyl 3 (morpholinomethyl) 6 (1 Naphthoyl) Pyrrolo [1, 3 De] [1, 4] Benzoxazine, 3 Trimethylbicyclo [2 2 1] Heptan 2 Yl) 3 Pyrazolecarboxamide,
Affiliations:
*** IBB - CNR ***
Dept. of Experimental Pharmacology, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy
Endocannabinoid Research Group, Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Naples, Italy
Ist. di Biostrutture e Bioimmagini, Consiglio Nazionale delle Ricerche, Via Mezzocannone 6, 80134 Naples, Italy
Comprensorio Olivetti, Ed. 70, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy
References:
Jones, K.A., (1993) Curr. Opin. Cell Biol., 5, pp. 461-46
Chang, H.K., Gallo, R.C., Ensoli, B., (1995) J. Biomed. Sci., 2, pp. 189-202
Watson, K., Edwards, R.J., (1999) Biochem. Pharmacol., 58, pp. 1521-1528
Ensoli, B., Bonaguro, L., Barillari, G., Fiorelli, B., Gentleman, R., Morgan, R.A., Wingfield, P., Gallo, R.C., (1993) J. Virol., 67, pp. 277-287
Tardieu, M., Hery, C., Peudenier, S., Boespflug, O., Montagnier, L., (1992) Ann. Neurol., 32, pp. 11-17
Epstein, L.G., Gendelman, H.E., Lipton, S.A., (1997) AIDS and the Nervous System, pp. 59-75. , (Berger, J. R., and Levy, R. M., eds) 2nd, Lippincott-Raven Publishers, Philadelphia
Orsini, M.J., Debouck, C.M., Webb, C.L., Lysko, P.G., (1996) J. Neurosci., 16, pp. 2546-2552
New, D.R., Maggirwar, S.B., Epstein, L.G., Dehwurst, S., Gelbard, H.A., (1998) J. Biol. Chem., 273, pp. 17852-17858
Navia, B.A., Jordan, B.D., Price, R.W., (1986) Ann. Neurol., 19, pp. 517-524
Price, R.W., Brew, B., Sidtis, J., Rosenblum, M., Scheck, A.C., Cleary, P., (1988) Science, 239, pp. 586-592
Mechoulam, R., (1986) Cannabinoids as Therapeutic Agents, pp. 1-19. , Mechoulam, R., ed, CRC Press, Boca Raton, FL
Pertwee, R.G., (1997) Pharmacol. Ther., 74, pp. 129-180
Matsuda, L.A., Lolait, S.J., Brownstein, M.J., Young, A.C., Bonner, T.I., (1990) Nature, 346, pp. 561-564
Munro, S., Thomas, K.L., Abu-Shaar, M., (1993) Nature, 365, pp. 61-65
Galiegue, S., Mary, S., Marchand, J., Dussosoy, D., Carriere, D., Carayon, P., Bouaboula, M., Casellas, P., (1995) Eur. J. Bio. Chem., 232, pp. 54-61
Galve-Ropher, I., Sanchez, C., Cortes, M.L., Gomez del Pulgar, T., Izquierdo, M., Guzman, M., (2000) Nat. Med., 6, pp. 313-319
Devane, W.A., Hanus, L., Breuer, A., Pertewee, R.G., Stevenson, L.A., Griffin, G., Gibson, D., Mechoulam, R., (1992) Science, 258, pp. 1946-1949
Mechoulam, R., Ben Shabat, S., Hanus, L., Ligumsky, M., Kaminski, N.E., Shatz, A.R., Gopher, A., Vogel, Z., (1995) Biochem. Pharmacol., 50, pp. 83-90
Sugiura, T., Kondo, S., Sukagawa, A., Nakane, S., Shinode, A., Itoh, K., Yamashita, A., Waku, K., (1995) Biochem. Biophys. Res. Commun., 215, pp. 89-97
Di Marzo, V., Melck, D., Bisogno, T., De Petrocellis, V., (1998) Trends Neurosci., 21, pp. 521-528
Jin, K.L., Mao, X.O., Goldsmith, P.C., Greenberg, D.A., (2000) Ann. Neurol., 48, pp. 257-261
Hansen, H.H., Schmid, P.C., Bittigau, P., Lastres-Becker, I., Berrendero, F., Manzanares, J., Ikonomidou, C., Hansen, H.S., (2001) J. Neurochem., 78, pp. 1415-1427
Panikshavili, D., Simenoidou, C., Ben Shabat, S., Hanus, Breuer, L., Mechoulam, A., Shohami R., E., (2001) Nature, 413, pp. 527-531
Mechoulam, R., Spatz, M., Shohami, E., (2002) Sci. STKE, 129, pp. RE5
Coffey, R.G., Yamamoto, Y., Snella, E., Pross, S., (1996) Biochem. Pharmacol., 52, pp. 743-751
Jeon, Y.J., Yang, K.H., Pulaski, J.T., Kaminski, N.E., (1996) Mol. Pharmacol., 50, pp. 334-341
Waksman, J., Olson, J.M., Carlisle, J., Cabral, G.A., (1999) J. Pharmacol. Exp. Ther., 288, pp. 1357-1366
Esposito, G., Izzo, A.A., Di Rosa, M., Iuvone, T., (2001) J. Neurochem., 78, pp. 835-841
Knowles, R.G., Palacios, M., Palmer, R.M.J., Moncada, S., (1989) Proc. Natl. Acad. Sci. U. S. A., 86, pp. 5159-5162
Murphy, S., Minor R.L., Jr., Welk, G., Harrison, D.G., (1990) J. Neurochem., 55, pp. 349-351
Galea, E., Feinstein, D.L., Reis, D.J., (1992) Proc. Natl. Acad. Sci. U. S. A., 89, pp. 10945-10949
Mollace, V., Colasanti, M., Rodino, P., Massoud, R., Lauro, G.M., Nisticò, G., (1993) Biochem. Biophys. Res. Commun., 191, pp. 327-334
Garthwaite, J., (1991) Trends Neurosci., 14, pp. 60-67
Dawson, T.M., Snyder, S.H., (1994) J. Neurosci., 14, pp. 5147-5159
Dawson, V.L., Dawson, T.M., (1996) Proc. Soc. Exp. Biol. Med., 211, pp. 33-40
Bolanos, J.P., Almeida, A., Stewart, V., Peuchen, S., Land, J.M., Clark, J.B., Heales, S.J.R., (1997) J. Neurochem., 68, pp. 2227-2240
Meda, L., Cassatela, M.A., Szendrei, G.I., Ottvos L., Jr., Baron, P., Villalba, M., Ferrari, D., Rossi, F., (1995) Nature, 374, pp. 647-650
Chung, H., Brazil, M.I., Soe, T.T., Maxfield, F.R., (1999) J. Biol. Chem., 274, pp. 32301-32308
Vila, M., Jackson-Lewis, V., Guegan, C., Wu, D.C., Teismann, P., Choi, D.K., Tieu, K., Przedborski, S., (2001) Curr. Opin. Neurol., 14, pp. 483-489
Buttini, M., Appel, K., Sauter, A., Gebicke-Haerter, P.J., Boddeke, H.W., (1996) Neurosci., 71, pp. 1-16
Rothwell, N., Toulmond, S., Allan, S., Stroemer, P., Davies, C., (1999) Inflammatory Cells and Mediators in CNS Diseases, pp. 471-482. , Ruffolo, R. R., Feuersteiner, G. Z., Hunter, A. J., Poste, G., and Metcalf, B. W., eds, Harwood Academic Publisher, Canada
Ruvo, M., Scarallo, A., Vecchio, G., Palombo, G., Fassina, G., (1996) Peptides, pp. 771-772. , Ramage, R., and Epton, R., eds, Mayflower Scientific, Ltd., Kingswinford West Midlands, UK
Polazzi, E., Levi, G., Minghetti, L., (1999) J. Neuropathol. Exp. Neurol., 58, pp. 825-831
Di Rosa, M., Radomski, R.M., Carnuccio, R., Moncada, S., (1990) Biochem. Biophys. Res. Comm., 172, pp. 1246-1252
Esposito, G., Aiello, A., Carbonelli, S., Menna, M.L., Fattorusso, E., Iuvone, T., (2002) Anticancer Res., 22, pp. 2827-2832
Bisogno, T., Maccarrone, M., De Petrocellis, L., Jarrahian, A., Finazzi-Agro, A., Hillard, C., Di Marzo, V., (2001) Eur. J. Biochem., 268, pp. 1982-1989
Bisogno, T., Maurelli, S., Melck, D., De Petrocellis, L., Di Marzo, V., (1997) J. Biol. Chem., 272, pp. 3315-3323
Adamson, D.C., Wildemann, B., Sasaki, M., Glass, J.D., McArtur, J., Christov, V.I., Dawson, T.M., Dawson, V.L., (1996) Science, 274, pp. 1917-1921
Gavril, E.S., Cooney, R., Weeks, B.S., (2000) Biochem. Biophys. Res. Comm., 267, pp. 252-256
Kim, H., Kim, Y.S., Kim, S.Y., Suk, K., (2001) Neurosci. Letts, 309, pp. 67-71
Suk, K., Kim, S.Y., Kim, H., (2002) J. Neurochem., 80, pp. 230-238
Rinaldi-Carmona, M., Le Duigou, A., Oustric, D., Barth, F., Bouaboula, M., Carayon, P., Casellas, P., Le Fur, G., (1998) J. Pharmacol. Exp. Ther., 287, pp. 1038-1047
Jin, W., Brown, S., Roche, J.P., Hsieh, C., Celver, J.P., Kovoor, A., Chavkin, C., Mackie, K., (1999) J. Neurosci., 19, pp. 3773-3780
Maccarrone, M., Bari, M., Lorenzon, T., Bisogno, T., Di Marzo, V., FinazziAgro, A., (2000) J. Biol. Chem., 275, pp. 13484-13492
Jones, K. A., (1993) Curr. Opin. Cell Biol., 5, pp. 461-46
Chang, H. K., Gallo, R. C., Ensoli, B., (1995) J. Biomed. Sci., 2, pp. 189-202
Epstein, L. G., Gendelman, H. E., Lipton, S. A., (1997) AIDS and the Nervous System, pp. 59-75. , (Berger, J. R., and Levy, R. M., eds) 2nd, Lippincott-Raven Publishers, Philadelphia
Orsini, M. J., Debouck, C. M., Webb, C. L., Lysko, P. G., (1996) J. Neurosci., 16, pp. 2546-2552
New, D. R., Maggirwar, S. B., Epstein, L. G., Dehwurst, S., Gelbard, H. A., (1998) J. Biol. Chem., 273, pp. 17852-17858
Navia, B. A., Jordan, B. D., Price, R. W., (1986) Ann. Neurol., 19, pp. 517-524
Price, R. W., Brew, B., Sidtis, J., Rosenblum, M., Scheck, A. C., Cleary, P., (1988) Science, 239, pp. 586-592
Pertwee, R. G., (1997) Pharmacol. Ther., 74, pp. 129-180
Matsuda, L. A., Lolait, S. J., Brownstein, M. J., Young, A. C., Bonner, T. I., (1990) Nature, 346, pp. 561-564
Devane, W. A., Hanus, L., Breuer, A., Pertewee, R. G., Stevenson, L. A., Griffin, G., Gibson, D., Mechoulam, R., (1992) Science, 258, pp. 1946-1949
Jin, K. L., Mao, X. O., Goldsmith, P. C., Greenberg, D. A., (2000) Ann. Neurol., 48, pp. 257-261
Hansen, H. H., Schmid, P. C., Bittigau, P., Lastres-Becker, I., Berrendero, F., Manzanares, J., Ikonomidou, C., Hansen, H. S., (2001) J. Neurochem., 78, pp. 1415-1427
Coffey, R. G., Yamamoto, Y., Snella, E., Pross, S., (1996) Biochem. Pharmacol., 52, pp. 743-751
Jeon, Y. J., Yang, K. H., Pulaski, J. T., Kaminski, N. E., (1996) Mol. Pharmacol., 50, pp. 334-341
Knowles, R. G., Palacios, M., Palmer, R. M. J., Moncada, S., (1989) Proc. Natl. Acad. Sci. U. S. A., 86, pp. 5159-5162
Dawson, T. M., Snyder, S. H., (1994) J. Neurosci., 14, pp. 5147-5159
Dawson, V. L., Dawson, T. M., (1996) Proc. Soc. Exp. Biol. Med., 211, pp. 33-40
Bolanos, J. P., Almeida, A., Stewart, V., Peuchen, S., Land, J. M., Clark, J. B., Heales, S. J. R., (1997) J. Neurochem., 68, pp. 2227-2240
Adamson, D. C., Wildemann, B., Sasaki, M., Glass, J. D., McArtur, J., Christov, V. I., Dawson, T. M., Dawson, V. L., (1996) Science, 274, pp. 1917-1921
Gavril, E. S., Cooney, R., Weeks, B. S., (2000) Biochem. Biophys. Res. Comm., 267, pp. 252-256
Kim, H., Kim, Y. S., Kim, S. Y., Suk, K., (2001) Neurosci. Letts, 309, pp. 67-71
Suk, K., Kim, S. Y., Kim, H., (2002) J. Neurochem., 80, pp. 230-238
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2002 Dec 27; 277(52): 50348-50354.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 6.696, 5-year impact factor: 4.863
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0347297582&partnerID=40&md5=2d7814af3182f86e498c841a7a2117ab
Keywords: Cytology, Hydrolysis, Immunology, Neurology, Nitric Acid, Proteins, Synthesis (chemical), Toxicity, Glioma Cells, 2 Methyl 3 (1 Naphthoyl) 1 Propylindole, 3 Dihydro 5 Methyl 3 (morpholinomethyl) 6 (1 Naphthoyl)pyrrolo[1, 3 De][1, 4]benzoxazine, 5 (4 Chloro 3 Methylphenyl) 1 (4 Methylbenzyl) N (1, 3 Trimethylbicyclo[2 2 1]heptan 2 Yl) 3 Pyrazolecarboxamide, Anandamide, Arginine, Cannabinoid, Cannabinoid 1 Receptor, Cannabinoid 2 Receptor, Cannabinoid Receptor Agonist, Gamma Interferon, Nitric Oxide Synthase, Rimonabant, Transactivator Protein, Animal Cell, Article, Controlled Study, Cytotoxicity, Drug Effect, Drug Inhibition, Human Immunodeficiency Virus 1, Nonhuman, Priority Journal, Protection, Protein Expression, Bornanes, Cell Survival, Endocannabinoids, Gene Expression Regulation, Enzymologic, Neoplastic, Gene Products, Hiv-1, Naphthalenes, Nitric Oxide Donors, Nitric Oxide Synthase Type Ii, Peptide Fragments, Reverse Transcriptase Polymerase Chain Reaction, Tumor Cells, Cultured, 3 Dihydro 5 Methyl 3 (morpholinomethyl) 6 (1 Naphthoyl) Pyrrolo [1, 3 De] [1, 4] Benzoxazine, 3 Trimethylbicyclo [2 2 1] Heptan 2 Yl) 3 Pyrazolecarboxamide,
Affiliations:
*** IBB - CNR ***
Dept. of Experimental Pharmacology, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy
Endocannabinoid Research Group, Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Naples, Italy
Ist. di Biostrutture e Bioimmagini, Consiglio Nazionale delle Ricerche, Via Mezzocannone 6, 80134 Naples, Italy
Comprensorio Olivetti, Ed. 70, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy
References:
Jones, K.A., (1993) Curr. Opin. Cell Biol., 5, pp. 461-46
Chang, H.K., Gallo, R.C., Ensoli, B., (1995) J. Biomed. Sci., 2, pp. 189-202
Watson, K., Edwards, R.J., (1999) Biochem. Pharmacol., 58, pp. 1521-1528
Ensoli, B., Bonaguro, L., Barillari, G., Fiorelli, B., Gentleman, R., Morgan, R.A., Wingfield, P., Gallo, R.C., (1993) J. Virol., 67, pp. 277-287
Tardieu, M., Hery, C., Peudenier, S., Boespflug, O., Montagnier, L., (1992) Ann. Neurol., 32, pp. 11-17
Epstein, L.G., Gendelman, H.E., Lipton, S.A., (1997) AIDS and the Nervous System, pp. 59-75. , (Berger, J. R., and Levy, R. M., eds) 2nd, Lippincott-Raven Publishers, Philadelphia
Orsini, M.J., Debouck, C.M., Webb, C.L., Lysko, P.G., (1996) J. Neurosci., 16, pp. 2546-2552
New, D.R., Maggirwar, S.B., Epstein, L.G., Dehwurst, S., Gelbard, H.A., (1998) J. Biol. Chem., 273, pp. 17852-17858
Navia, B.A., Jordan, B.D., Price, R.W., (1986) Ann. Neurol., 19, pp. 517-524
Price, R.W., Brew, B., Sidtis, J., Rosenblum, M., Scheck, A.C., Cleary, P., (1988) Science, 239, pp. 586-592
Mechoulam, R., (1986) Cannabinoids as Therapeutic Agents, pp. 1-19. , Mechoulam, R., ed, CRC Press, Boca Raton, FL
Pertwee, R.G., (1997) Pharmacol. Ther., 74, pp. 129-180
Matsuda, L.A., Lolait, S.J., Brownstein, M.J., Young, A.C., Bonner, T.I., (1990) Nature, 346, pp. 561-564
Munro, S., Thomas, K.L., Abu-Shaar, M., (1993) Nature, 365, pp. 61-65
Galiegue, S., Mary, S., Marchand, J., Dussosoy, D., Carriere, D., Carayon, P., Bouaboula, M., Casellas, P., (1995) Eur. J. Bio. Chem., 232, pp. 54-61
Galve-Ropher, I., Sanchez, C., Cortes, M.L., Gomez del Pulgar, T., Izquierdo, M., Guzman, M., (2000) Nat. Med., 6, pp. 313-319
Devane, W.A., Hanus, L., Breuer, A., Pertewee, R.G., Stevenson, L.A., Griffin, G., Gibson, D., Mechoulam, R., (1992) Science, 258, pp. 1946-1949
Mechoulam, R., Ben Shabat, S., Hanus, L., Ligumsky, M., Kaminski, N.E., Shatz, A.R., Gopher, A., Vogel, Z., (1995) Biochem. Pharmacol., 50, pp. 83-90
Sugiura, T., Kondo, S., Sukagawa, A., Nakane, S., Shinode, A., Itoh, K., Yamashita, A., Waku, K., (1995) Biochem. Biophys. Res. Commun., 215, pp. 89-97
Di Marzo, V., Melck, D., Bisogno, T., De Petrocellis, V., (1998) Trends Neurosci., 21, pp. 521-528
Jin, K.L., Mao, X.O., Goldsmith, P.C., Greenberg, D.A., (2000) Ann. Neurol., 48, pp. 257-261
Hansen, H.H., Schmid, P.C., Bittigau, P., Lastres-Becker, I., Berrendero, F., Manzanares, J., Ikonomidou, C., Hansen, H.S., (2001) J. Neurochem., 78, pp. 1415-1427
Panikshavili, D., Simenoidou, C., Ben Shabat, S., Hanus, Breuer, L., Mechoulam, A., Shohami R., E., (2001) Nature, 413, pp. 527-531
Mechoulam, R., Spatz, M., Shohami, E., (2002) Sci. STKE, 129, pp. RE5
Coffey, R.G., Yamamoto, Y., Snella, E., Pross, S., (1996) Biochem. Pharmacol., 52, pp. 743-751
Jeon, Y.J., Yang, K.H., Pulaski, J.T., Kaminski, N.E., (1996) Mol. Pharmacol., 50, pp. 334-341
Waksman, J., Olson, J.M., Carlisle, J., Cabral, G.A., (1999) J. Pharmacol. Exp. Ther., 288, pp. 1357-1366
Esposito, G., Izzo, A.A., Di Rosa, M., Iuvone, T., (2001) J. Neurochem., 78, pp. 835-841
Knowles, R.G., Palacios, M., Palmer, R.M.J., Moncada, S., (1989) Proc. Natl. Acad. Sci. U. S. A., 86, pp. 5159-5162
Murphy, S., Minor R.L., Jr., Welk, G., Harrison, D.G., (1990) J. Neurochem., 55, pp. 349-351
Galea, E., Feinstein, D.L., Reis, D.J., (1992) Proc. Natl. Acad. Sci. U. S. A., 89, pp. 10945-10949
Mollace, V., Colasanti, M., Rodino, P., Massoud, R., Lauro, G.M., Nisticò, G., (1993) Biochem. Biophys. Res. Commun., 191, pp. 327-334
Garthwaite, J., (1991) Trends Neurosci., 14, pp. 60-67
Dawson, T.M., Snyder, S.H., (1994) J. Neurosci., 14, pp. 5147-5159
Dawson, V.L., Dawson, T.M., (1996) Proc. Soc. Exp. Biol. Med., 211, pp. 33-40
Bolanos, J.P., Almeida, A., Stewart, V., Peuchen, S., Land, J.M., Clark, J.B., Heales, S.J.R., (1997) J. Neurochem., 68, pp. 2227-2240
Meda, L., Cassatela, M.A., Szendrei, G.I., Ottvos L., Jr., Baron, P., Villalba, M., Ferrari, D., Rossi, F., (1995) Nature, 374, pp. 647-650
Chung, H., Brazil, M.I., Soe, T.T., Maxfield, F.R., (1999) J. Biol. Chem., 274, pp. 32301-32308
Vila, M., Jackson-Lewis, V., Guegan, C., Wu, D.C., Teismann, P., Choi, D.K., Tieu, K., Przedborski, S., (2001) Curr. Opin. Neurol., 14, pp. 483-489
Buttini, M., Appel, K., Sauter, A., Gebicke-Haerter, P.J., Boddeke, H.W., (1996) Neurosci., 71, pp. 1-16
Rothwell, N., Toulmond, S., Allan, S., Stroemer, P., Davies, C., (1999) Inflammatory Cells and Mediators in CNS Diseases, pp. 471-482. , Ruffolo, R. R., Feuersteiner, G. Z., Hunter, A. J., Poste, G., and Metcalf, B. W., eds, Harwood Academic Publisher, Canada
Ruvo, M., Scarallo, A., Vecchio, G., Palombo, G., Fassina, G., (1996) Peptides, pp. 771-772. , Ramage, R., and Epton, R., eds, Mayflower Scientific, Ltd., Kingswinford West Midlands, UK
Polazzi, E., Levi, G., Minghetti, L., (1999) J. Neuropathol. Exp. Neurol., 58, pp. 825-831
Di Rosa, M., Radomski, R.M., Carnuccio, R., Moncada, S., (1990) Biochem. Biophys. Res. Comm., 172, pp. 1246-1252
Esposito, G., Aiello, A., Carbonelli, S., Menna, M.L., Fattorusso, E., Iuvone, T., (2002) Anticancer Res., 22, pp. 2827-2832
Bisogno, T., Maccarrone, M., De Petrocellis, L., Jarrahian, A., Finazzi-Agro, A., Hillard, C., Di Marzo, V., (2001) Eur. J. Biochem., 268, pp. 1982-1989
Bisogno, T., Maurelli, S., Melck, D., De Petrocellis, L., Di Marzo, V., (1997) J. Biol. Chem., 272, pp. 3315-3323
Adamson, D.C., Wildemann, B., Sasaki, M., Glass, J.D., McArtur, J., Christov, V.I., Dawson, T.M., Dawson, V.L., (1996) Science, 274, pp. 1917-1921
Gavril, E.S., Cooney, R., Weeks, B.S., (2000) Biochem. Biophys. Res. Comm., 267, pp. 252-256
Kim, H., Kim, Y.S., Kim, S.Y., Suk, K., (2001) Neurosci. Letts, 309, pp. 67-71
Suk, K., Kim, S.Y., Kim, H., (2002) J. Neurochem., 80, pp. 230-238
Rinaldi-Carmona, M., Le Duigou, A., Oustric, D., Barth, F., Bouaboula, M., Carayon, P., Casellas, P., Le Fur, G., (1998) J. Pharmacol. Exp. Ther., 287, pp. 1038-1047
Jin, W., Brown, S., Roche, J.P., Hsieh, C., Celver, J.P., Kovoor, A., Chavkin, C., Mackie, K., (1999) J. Neurosci., 19, pp. 3773-3780
Maccarrone, M., Bari, M., Lorenzon, T., Bisogno, T., Di Marzo, V., FinazziAgro, A., (2000) J. Biol. Chem., 275, pp. 13484-13492
Jones, K. A., (1993) Curr. Opin. Cell Biol., 5, pp. 461-46
Chang, H. K., Gallo, R. C., Ensoli, B., (1995) J. Biomed. Sci., 2, pp. 189-202
Epstein, L. G., Gendelman, H. E., Lipton, S. A., (1997) AIDS and the Nervous System, pp. 59-75. , (Berger, J. R., and Levy, R. M., eds) 2nd, Lippincott-Raven Publishers, Philadelphia
Orsini, M. J., Debouck, C. M., Webb, C. L., Lysko, P. G., (1996) J. Neurosci., 16, pp. 2546-2552
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The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity: Mechanism and regulation
Cannabinoids modulate nitric oxide (NO) levels in cells of the central nervous system. Here we studied the effect of cannabinoid CB1 and CB2 receptor agonists on the release of NO and cell toxicity induced by the human immuno-deficiency virus-1 Tat protein (HIV-1 Tat) in rat glioma C6 cells. The CB1 and CB2 agonist WIN 55,212-2 inhibited the expression of inducible NO synthase (iNOS) and NO release caused by treatment of C6 cells with HIV-1 Tat and interferon-γ (IFN-γ). The effect of WIN 55,212-2 was uniquely due to CB1 receptors, as shown by experiments carried out with selective CB1 and CB2 receptor agonists and antagonists. CB1 receptor stimulation also inhibited HIV-1 Tat + IFN-γ-induced and NO-mediated cell toxicity. Moreover, cell treatment with HIV-1 Tat + IFN-γ induced a significant inhibition of CB1, but not CB2, receptor expression. This effect was mimicked by the NO donor GSNO, suggesting that the inhibition of CB1 expression was due to HIV-1 Tat + IFN-γ-induced NO overexpression. HIV-1 Tat + IFN-γ treatment also induced a significant inhibition of the uptake of the endocannabinoid anandamide by C6 cells with no effect on anandamide hydrolysis. These findings show that the endocannabinoid system, through the modulation of the L-arginine/NO pathway, reduces HIV-1 Tat-induced cytotoxicity, and is itself regulated by HIV-1 Tat.
Cannabinoids modulate nitric oxide (NO) levels in cells of the central nervous system. Here we studied the effect of cannabinoid CB1 and CB2 receptor agonists on the release of NO and cell toxicity induced by the human immuno-deficiency virus-1 Tat protein (HIV-1 Tat) in rat glioma C6 cells. The CB1 and CB2 agonist WIN 55,212-2 inhibited the expression of inducible NO synthase (iNOS) and NO release caused by treatment of C6 cells with HIV-1 Tat and interferon-γ (IFN-γ). The effect of WIN 55,212-2 was uniquely due to CB1 receptors, as shown by experiments carried out with selective CB1 and CB2 receptor agonists and antagonists. CB1 receptor stimulation also inhibited HIV-1 Tat + IFN-γ-induced and NO-mediated cell toxicity. Moreover, cell treatment with HIV-1 Tat + IFN-γ induced a significant inhibition of CB1, but not CB2, receptor expression. This effect was mimicked by the NO donor GSNO, suggesting that the inhibition of CB1 expression was due to HIV-1 Tat + IFN-γ-induced NO overexpression. HIV-1 Tat + IFN-γ treatment also induced a significant inhibition of the uptake of the endocannabinoid anandamide by C6 cells with no effect on anandamide hydrolysis. These findings show that the endocannabinoid system, through the modulation of the L-arginine/NO pathway, reduces HIV-1 Tat-induced cytotoxicity, and is itself regulated by HIV-1 Tat.
The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity: Mechanism and regulation
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The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity: Mechanism and regulation
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De Simone G
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Palmieri C, Falcone C, Iaccino E, Tuccillo FM, Gaspari M, Trimboli F, De Laurentiis A, Luberto L, Pontoriero M, Pisano A, Vecchio E, Fierro O, Panico M, Larobina M, Gargiulo S, Costa N, Dal Piaz F, Schiavone M, Arra C, Giudice A, Palma G, Barbieri A, Quinto I, Scala G
* In vivo targeting and growth inhibition of the A20 murine B-cell lymphoma by an idiotype-specific peptide binder (557 views)
Blood (ISSN: 0006-4971, 0006-6497, 0390-6078), 2010 Jul 15; 116(2): 226-238.
Impact Factor: 10.558
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La Mendola D, Magrì A, Campagna T, Campitiello MA, Raiola L, Isernia C, Hansson O, Bonomo RP, Rizzarelli E
* A doppel alpha-helix peptide fragment mimics the copper(II) interactions with the whole protein (1058 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2010 Jun 1; 16(21): 6212-6223.
Impact Factor: 5.476
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Castellano I, Merlino A, Rossi M, La Cara F
* Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity (586 views)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2010 May; 92(5): 464-474.
Impact Factor: 3.787
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Napolitano M, Ottaiano A, Mauro F, Ieranò C, Satriano R, Pacelli R, Franco R, De Angelis V, Castello G, Scala S
* CD4(+)CD45RA(+)CXCR4(+) lymphocytes are inversely associated with progression in stages I-III melanoma patients (351 views)
Cancer Immunol Immunother (ISSN: 0340-7004, 0340-7004linking), 2010 Apr; 59(4): 511-517.
Impact Factor: 4.293
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Kaczmarek K, Farina B, Zubrzak P, Jankowski S, Zimecki M, Suder P, Benedetti E, Fattorusso R, Saviano M, Zabrocki J
* Synthesis, conformational analysis and immunological activity of β3Phe-substituted Cyclolinopeptide A analogues (449 views)
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Impact Factor: 1.807
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Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M
* Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity (443 views)
J Mol Biol (ISSN: 1089-8638, 0022-2836, 1089-8638electronic), 2009 Feb 6; 385(5): 1556-1567.
Impact Factor: 3.871
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Mandrich L, Menchise V, Alterio V, De Simone G, Pedone C, Rossi M, Manco G
* Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius (399 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2008 Jun; 71(4): 1721-1731.
Impact Factor: 3.419
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Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (436 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
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Saporito A, Marasco D, Chambery A, Botti P, Monti SM, Pedone C, Ruvo M
* The chemical synthesis of the GstI protein by NCL on a X-Met site (605 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2006 Dec 5; 83(5): 508-518.
Impact Factor: 2.48
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Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* A new spot test for sulfhydryl-containing compounds (432 views)
Anal Biochem, 2006 Mar 14; 79(1-2): 610-611.
Impact Factor: 2.305
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Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (654 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Mar 14; 45(10): 3226-3234.
Impact Factor: 3.633
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Cucinotta V, Giuffrida A, Maccarrone G, Messina M, Puglisi A, Rizzarelli E, Vecchio G
* Coordination properties of 3-functionalized β-cyclodextrins. Thermodynamic stereoselectivity of copper(II) complexes of the A, B-diamino derivative and its exploitation in LECE (347 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2005 Sep 21; (16): 2731-2736.
Impact Factor: 3.003
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Zubrzak P, Banas A, Kaczmarek K, Leplawy MT, Sochacki M, Kowalski ML, Szkudlinska B, Zabrocki J, Di Lello P, Isernia C, Saviano M, Pedone C, Benedetti E
* Analogues of cyclolinopeptide A containing alpha-hydroxymethyl amino acid residues (442 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2005; 80(2-3): 347-356.
Impact Factor: 2.425
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De Simone G, Mandrich L, Menchise V, Giordano V, Febbraio F, Rossi M, Pedone C, Manco G
* A substrate-induced switch in the reaction mechanism of a thermophilic esterase - Kinetic evidences and structural basis (381 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2004 Feb 20; 279(8): 6815-6823.
Impact Factor: 6.355
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Caridi A, Cufari A, Lovino R, Palumbo R, Tedesco I
* Influence of Yeast on Polyphenol Composition of Wine (227 views)
Food Technol Biotechnol (ISSN: 1330-9862), 2004 Jan; 42(1): 37-40.
Impact Factor: 0.475
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Mangiapia G, Accardo A, Celso FL, Tesauro D, Morelli G, Radulescu A, Paduano L
* Mixed micelles composed of peptides and gadolinium complexes as tumor-specific contrast agents in MRI: A sans study (563 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2004; 108(45): 17611-17617.
Impact Factor: 3.834
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Lombardi A, Nastri F, Marasco D, Maglio O, De Sanctis G, Sinibaldi F, Santucci R, Coletta M, Pavone V
* Design of a new mimochrome with unique topology (472 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2003 Nov 21; 9(22): 5643-5654.
Impact Factor: 4.353
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Galdiero M, Vitiello M, Galdiero S
* Eukaryotic cell signaling and transcriptional activation induced by bacterial porins (402 views)
Fems Microbiology Letters (ISSN: 0378-1097), 2003 Sep 12; 226(1): 57-64.
Impact Factor: 1.932
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De Simone G, Menchise V, Omaggio S, Pedone C, Scozzafava A, Supuran CT
* Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: Molecular and X-ray crystallographic studies (332 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2003 Sep 5; 42(30): 9013-9021.
Impact Factor: 3.922
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Formaggio F, Crisma M, Toniolo C, Broxterman QB, Kaptein B, Corbier C, Saviano M, Palladino P, Benedetti E
* Cα-Methyl, Cα-n-Propylglycine Homo-oligomers (292 views)
Macromolecules (ISSN: 0024-9297), 2003; 36(21): 8164-8170.
Impact Factor: 3.621
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Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (364 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
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Peggion C, Formaggio F, Crisma M, Toniolo C, Jimenez AI, Cativiela C, Kaptein B, Broxterman QB, Saviano M, Benedetti E
* Folding of peptides characterized by c3Val, a highly constrained analogue of valine (385 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003; 68(2): 178-191.
Impact Factor: 2.733
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Maglio O, Saldanha JW, Vrtala S, Spitzauer S, Valenta R, Pastore A
* A major IgE epitope-containing grass pollen allergen domain from Phl p 5 folds as a four-helix bundle (485 views)
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Impact Factor: 2.126
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Renda A, Iovino F, Capasso L, Ricciardelli L, Tammaro V, Acampa W
Radioimmunoguided surgery in colorectal cancer: A 6-year experience with four different technical solutions (259 views)
Semin Surg Oncol Wiley Liss Inc (ISSN: 8756-0437), 1998 Dec; 15(4): 226-230.
Impact Factor: 1.045
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D'Andrea LD, Mazzeo M, Isernia C, Rossi F, Saviano M, Gallo P, Paolillo L, Pedone C
Solution conformational preferences of a peptidic analogue of a natural macrolide (357 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1997; 42(3): 349-361.
Impact Factor: 2.425
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Lombardi A, Saviano M, Nastri F, Maglio O, Mazzeo M, Pedone C, Isernia C, Pavone V
Unusual conformational preferences of β-alanine containing cyclic peptides. VII (450 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1996 Jun; 38(6): 683-691.
Impact Factor: 2.425
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Lombardi A, D'Auria G, Saviano M, Maglio O, Nastri F, Quartara L, Pedone C, Pavone V
Bicyclic Peptides As Type I/Type Ii Beta-Turn Scaffolds (504 views)
Biopolym Pept Sci Sect, 1996; 40(5): 505-518.
Impact Factor: 0
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Wink DA, Hanbauer I, Grisham MB, Laval F, Nims RW, Laval J, Cook J, Pacelli R, Liebmann J, Krishna M, Ford PC, Mitchell JB
Chemical biology of nitric oxide: Regulation and protective and toxic mechanisms (528 views)
Current Topics In Cellular Regulation (ISSN: 0070-2137), 1996; 34: 159-187.
Impact Factor: 4.375
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Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (359 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
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Rossi F, Saviano M, Di Talia P, Di Blasio B, Pedone C, Zanotti G, Mosca M, Saviano G, Tancredi T, Ziegler K, Benedetti E
Solution and solid state structure of an aib-containing cyclodecapeptide inhibiting the cholate uptake in hepatocytes (447 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1996; 40(5): 465-478.
Impact Factor: 2.425
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Pavone V, Lombardi A, Saviano M, Di Blasio B, Nastri F, Fattorusso R, Zaccaro L, Maglio O, Yamada T, Omote Y
Mixed conformation in C(α, α)-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-OMe and Bz-Dph-Dph-Gly-OMe (374 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1994 Dec; 34(12): 1595-1604.
Impact Factor: 2.425
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Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (225 views)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
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Zanotti G, Maione A, Rossi F, Saviano M, Pedone C, Tancredi T
BIOACTIVE PEPTIDES - CONFORMATIONAL STUDY OF A CYSTINYL CYCLOHEPTAPEPTIDE IN ITS FREE AND CALCIUM COMPLEXED FORMS (564 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1993 Jul; 33(7): 1083-1091.
Impact Factor: 2.425
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Di Blasio B, Lombardi A, D'Auria G, Saviano M, Isernia C, Maglio O, Paolillo L, Pedone C, Pavone V
Beta-Alanine Containing Peptides: Gamma-Turns In Cyclotetrapeptides (537 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1993 Apr; 31(10): 621-631.
Impact Factor: 2.425
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Della Ragione F, Oliva A, Palumbo R, Russo GL, Gragnaniello V, Zappia V
Deficiency of 5'-deoxy-5'-methylthioadenosine phosphorylase activity in malignancy. Absence of the protein in human enzyme-deficient cell lines (273 views)
Biochem J (ISSN: 0264-6021print, 0264-6021linking, 1470-8728electronic), 1992 Jan 15; 281(Pt2): 533-538.
Impact Factor: 3.579
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Del Vecchio S, Camera L, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Clinical studies with B72. 3 in ovarian cancer and probe-guided tumor localization (380 views)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1991; 18(1): 85-87.
Impact Factor: 1.042
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Della Ragione F, Oliva A, Gragnaniello V, Russo GL, Palumbo R, Zappia V
Physicochemical and immunological studies on mammalian 5'-deoxy-5'-methylthioadenosine phosphorylase (24 views) (PDF 7 views)
J Biol Chem (ISSN: 0021-9258linking), 1990 Apr 15; 265(11): 6241-6246.
Impact Factor: 5.328
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Steis RG, Carrasquillo JA, Mccabe R, Bookman MA, Reynolds JC, Larson SM, Smith JW, Clark JW, Dailey V, Del Vecchio S
Toxicity, immunogenicity, and tumor radioimmunodetecting ability of two human monoclonal antibodies in patients with metastatic colorectal carcinoma (283 views)
J Clin Oncol (ISSN: 0732-183x, 0732-183xlinking), 1990 Mar; 8(3): 476-490.
Impact Factor: 7.878
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Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (582 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
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Della Ragione F, Oliva A, Fioretti M, Russo GL, Palumbo R, Zappia V
Physico-chemical and immunological properties of bovine liver 5'-deoxy-5'-methylthioadenosine phosphorylase (472 views)
Adv Exp Med Biol (ISSN: 0065-2598print, 0065-2598linking), 1988; 250: 187-197.
Impact Factor: 0.36
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* A structure-based approach for the development of a bicyclic peptide acting as a miniaturized anti-CD55 antibody (24 views) (PDF 7 views)
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2021 May 17; 182: 1455-1462.
Impact Factor: 6.95
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Sivaccumar JP, Leonardi A, Iaccarino E, Corvino G, Sanguigno L, Chambery A, Russo R, Valletta M, Latino D, Capasso D, Doti N, Ruvo M, Sandomenico A
* Development of a New Highly Selective Monoclonal Antibody against Preferentially Expressed Antigen in Melanoma (PRAME) and Identification of the Target Epitope by Bio-Layer Interferometry (11 views)
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Impact Factor: 4.556
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Grund ME, Soo JC, Cote CK, Berisio R, Lukomski S
* Thinking Outside the Bug: Targeting Outer Membrane Proteins for Burkholderia Vaccines (16 views)
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2021 Feb 25; 10(3): N/D-N/D.
Impact Factor: 6.6
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Kramarska E, Squeglia F, De Maio F, Delogu G, Berisio R
* PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response (13 views)
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Impact Factor: 6.6
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Famulari ES, Navarro-tableros V, Herrera Sanchez MB, Bortolussi G, Gai M, Conti L, Silengo L, Tolosano E, Tetta C, Muro AF, Camussi G, Fagoonee S, Altruda F
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Impact Factor: 5.078
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Negri R, Trinchese G, Carbone F, Caprio MG, Stanzione G, Di Scala C, Micillo T, Perna F, Tarotto L, Gelzo M, Cavaliere G, Spagnuolo MI, Corso G, Mattace Raso G, Matarese G, Mollica MP, Greco L, Iorio R
* Randomised Clinical Trial: Calorie Restriction Regimen with Tomato Juice Supplementation Ameliorates Oxidative Stress and Preserves a Proper Immune Surveillance Modulating Mitochondrial Bioenergetics of T-Lymphocytes in Obese Children Affected by Non-Alcoholic Fatty Liver Disease (NAFLD) (98 views) (PDF 83 views)
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Impact Factor: 5.688
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Squeglia F, Moreira M, Ruggiero A, Berisio R
* The Cell Wall Hydrolytic NlpC/P60 Endopeptidases in Mycobacterial Cytokinesis: A Structural Perspective (200 views)
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Impact Factor: 5.7
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Di Stasi R, De Rosa L, Diana D, Fattorusso R, D'Andrea LD
* Human Recombinant VEGFR2D4 Biochemical Characterization to Investigate Novel Anti-VEGFR2D4 Antibodies for Allosteric Targeting of VEGFR2 (253 views)
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Impact Factor: 2.275
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Lama A, Annunziata C, Coretti L, Pirozzi C, Di Guida F, Nitrato Izzo A, Cristiano C, Mollica MP, Chiariotti L, Pelagalli A, Lembo F, Meli R, Mattace Raso G
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Impact Factor: 5.078
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Foca G, Iaccarino E, Foca A, Sanguigno L, Untiveros G, Cuevas-nunez M, Strizzi L, Leonardi A, Ruvo M, Sandomenico A
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Impact Factor: 3.787
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De Maio F, Squeglia F, Goletti D, Delogu G
* The Mycobacterial HBHA Protein: a Promising Biomarker for Tuberculosis (194 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2018 Oct 29; 26(11): 2051-2060.
Impact Factor: 3.519
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Fusco FA, Fiorentino G, Pedone E, Contursi P, Bartolucci S, Limauro D
* Biochemical characterization of a novel thermostable beta-glucosidase from Dictyoglomus turgidum (643 views)
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Impact Factor: 4.784
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Honarvar H, Calce E, Doti N, Langella E, Orlova A, Buijs J, D’amato V, Bianco R, Saviano M, Tolmachev V, De Luca S
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Impact Factor: 4.259
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Di Menna L, Joffe ME, Iacovelli L, Orlando R, Lindsley CW, Mairesse J, Gressèns P, Cannella M, Caraci F, Copani A, Bruno V, Battaglia G, Conn PJ, Nicoletti F
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Impact Factor: 3.383
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Berisio R, Squeglia F, Ruggiero A
* Editorial: Molecular Scenarios Behind Infectious Diseases (300 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3939-3941.
Impact Factor: 3.469
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Lanzillo R, Carbone F, Quarantelli M, Bruzzese D, Carotenuto A, De RosaV, Colamatteo A, Micillo T, De Luca Picione C, Saccà F, De Rosa A, Moccia M, Brescia Morra V, Matarese G
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Clin Immunol (ISSN: 1521-6616), 2017 Oct; 183: 249-253.
Impact Factor: 3.557
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Pontillo G, Cocozza S, Lanzillo R, Borrelli P, De Rosa A, Brescia Morra V, Tedeschi E, PalmaG
* Brain Susceptibility Changes in a Patient with Natalizumab-Related Progressive Multifocal Leukoencephalopathy: A Longitudinal Quantitative Susceptibility Mapping and Relaxometry Study (218 views)
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Impact Factor: 3.508
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Dennehy R, RomanoM, Ruggiero A, Mohamed YF, Dignam SL, Mujica Troncoso C, Callaghan M, Valvano MA, Berisio R, Mcclean S
* The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of inflammation (273 views)
Cell Microbiol (ISSN: 1462-5814), 2017 May; 19(5): e12691-e12691.
Impact Factor: 4.41
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Sandomenico A, Leonardi A, Berisio R, Sanguigno L, Foca G, Foca A, Ruggiero A, Doti N, Muscariello L, Barone D, Farina C, Owsianka A, Vitagliano L, Patel AH, Ruvo M
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J Virol (ISSN: 0022-538x, 0022-538xlinking), 2016 Jan 27; 90(7): 3745-3759.
Impact Factor: 4.663
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Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
* Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide (375 views)
Rsc Adv (ISSN: 2046-2069), 2016; 6(17): 14140-14148.
Impact Factor: 3.108
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Roviello GN, Roviello V, Autiero I, Saviano M
* Solid phase synthesis of TyrT, a thymine-tyrosine conjugate with poly(A) RNA-binding ability (484 views)
Rsc Adv (ISSN: 2046-2069), 2016; 6(33): 27607-27613.
Impact Factor: 3.108
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Karlsson J, Morgillo CM, Deplano A, Smaldone G, Pedone E, Luque FJ, Svensson M, Novellino E, Congiu C, Onnis V, Catalanotti B, Fowler CJ
* Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode (73 views)
Plosone (ISSN: 1932-6203linking, 1932-6203electronic), 2015 Nov 13; 10 (11 ): e0142711-N/D.
Impact Factor: 4.351
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Nikitushkin VD, Demina GR, Shleeva MO, Guryanova SV, Ruggiero A, Berisio R, Kaprelyants AS
* A product of RpfB and RipA joint enzymatic action promotes the resuscitation of dormant mycobacteria (457 views)
Febs J (ISSN: 1742-464x), 2015 Apr 3; 282(13): 2500-2511.
Impact Factor: 4.237
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Molinaro A, Holst O, Lorenzo FD, Callaghan M, Nurisso A, D'Errico G, Zamyatina A, Peri F, Berisio R, Jerala R, Jiménez-Barbero J, Silipo A, Martín-Santamarí S
* Chemistry of lipid a: At the heart of innate immunity (863 views) (PDF 295 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Jan 7; 21(2): 500-519.
Impact Factor: 5.771
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Speciale I, Paciello I, Fazio LL, Sturiale L, Palmigiano A, Lanzetta R, Parrilli M, Garozzo D, Lemaitre B, Bernardini ML, Molinaro A, De Castro C
* Determination of the structure of the O-antigen and the lipid A from the entomopathogenic bacterium Pseudomonas entomophila lipopolysaccharide along with its immunological properties (320 views)
Carbohyd Res (ISSN: 0008-6215, 0008-6215linking), 2015; 412: 20-27.
Impact Factor: 1.817
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Di Lorenzo F, Silipo A, Bianconi I, Lore' NI, Scamporrino A, Sturiale L, Garozzo D, Lanzetta R, Parrilli M, Bragonzi A, Molinaro A
* Persistent cystic fibrosis isolate Pseudomonas aeruginosa strain RP73 exhibits an under-acylated LPS structure responsible of its low inflammatory activity (336 views)
Mol Immunol (ISSN: 0161-5890), 2015; 63(2): 166-175.
Impact Factor: 3.375
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Morelli G, Saviano M, Grieco P
* The renaissance era of peptides in drug discovery at the 14th Naples workshop on bioactive peptides (399 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 321-322.
Impact Factor: 1.951
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Neve Polimeno M, Ierano C, D'Alterio C, Simona Losito N, Napolitano M, Portella L, Scognamiglio G, Tatangelo F, Maria Trotta A, Curley S, Costantini S, Liuzzi R, Izzo F, Scala S
* CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not (523 views)
Cell Mol Immunol (ISSN: 1672-7681), 2014 Nov 3; 12(4): 474-482.
Impact Factor: 4.112
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Altieri F, Di Stadio CS, Severino V, Sandomenico A, Minopoli G, Miselli G, Di Maro A, Ruvo M, Chambery A, Quagliariello V, Masullo M, Rippa E, Arcari P
* Anti-amyloidogenic property of human gastrokine (483 views)
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2014 Nov; 106C: 91-100.
Impact Factor: 2.963
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Accardo A, Vitiello M, Tesauro D, Galdiero M, Finamore E, Martora F, Mansi R, Ringhieri P, Morelli G
* Self-assembled or mixed peptide amphiphile micelles from herpes simplex virus glycoproteins as potential immunomodulatory treatment (453 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 May 7; 9(1): 2137-2148.
Impact Factor: 4.383
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Hayafune M, Berisio R, Marchetti R, Silipo A, Kayama M, Desaki Y, Arima S, Squeglia F, Ruggiero A, Tokuyasu K, Molinaro A, Kaku H, Shibuya N
* Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization (534 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2014 Jan 21; 111(3): E404-E404.
Impact Factor: 9.674
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Messori L, Scaletti F, Massai L, Cinellu MA, Russo Krauss I, Di Martino G, Vergara A, Paduano L, Merlino A
* Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(III) compound (313 views)
Metallomics (ISSN: 1756-5901, 1756-591x), 2014; 6(2): 233-236.
Impact Factor: 3.585
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Zhou JS, Sandomenico A, Burton O, Oettgen HC, Ruvo M
* An IgE receptor mimetic peptide (PepE) protects mice from IgE mediated anaphylaxis (410 views)
Molecular Biosystems (ISSN: 1742-206x), 2013 Nov; 9(11): 2853-2859.
Impact Factor: 3.183
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Madonna S, Scarponi C, Doti N, Carbone T, Cavani A, Scognamiglio PL, Marasco D, Albanesi C
* Therapeutical potential of a peptide mimicking the SOCS1 kinase inhibitory region in skin immune responses (548 views)
Eur J Immunol (ISSN: 0014-2980), 2013 Jul; 43(7): 1883-1895.
Impact Factor: 4.518
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Berisio R
* Learning from pathogens: Exploiting host-pathogen liaison for therapeutic development (364 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2012 Dec; 13(8): 697-698.
Impact Factor: 2.326
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Berisio R
* Editorial: cell processes in bacterial diseases (387 views)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1011-1012.
Impact Factor: 1.994
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Risitano AM, Imbriaco M, Marando L, Seneca E, Soscia E, Malcovati L, Iori AP, Pane F, Notaro R, Matarazzo M
* From perpetual haemosiderinuria to possible iron overload: iron redistribution in paroxysmal nocturnal haemoglobinuria patients on eculizumab by magnetic resonance imaging (325 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2012 Sep; 158(3): 415-418.
Impact Factor: 4.942
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Jószai V, Turi I, Kállay C, Pappalardo G, Di Natale G, Rizzarelli E, Sóvágó I
* Mixed metal copper(II)-nickel(II) and copper(II)-zinc(II) complexes of multihistidine peptide fragments of human prion protein (470 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Jul; 112: 17-24.
Impact Factor: 3.197
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Jacobs AH, Tavitian B, TheInmindG, Pappata S, Quarantelli M
* Noninvasive molecular imaging of neuroinflammation (326 views) (PDF 192 views)
J Cereb Blood Flow Metab (ISSN: 0271-678x, 1559-7016electronic), 2012 Jul; 32(7): 1393-1415.
Impact Factor: 5.398
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Truppo E, Supuran CT, Sandomenico A, Vullo D, Innocenti A, Di Fiore A, Alterio V, De Simone G, Monti SM
* Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors (348 views)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2012 Feb 15; 22(4): 1560-1564.
Impact Factor: 2.338
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De Simone G
* Editorial: Zinc Metallo-Enzymes As Target For Drug Design (354 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2012 Feb; 19(6): 820-1012.
Impact Factor: 4.07
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Galdiero S, Vitiello M, Finamore E, Mansi R, Galdiero M, Morelli G, Tesauro D
* Activation of monocytic cells by immunostimulatory lipids conjugated to peptide antigens (366 views)
Molecular Biosystems (ISSN: 1742-206x), 2012; 8(12): 3166-3177.
Impact Factor: 3.35
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Castellano I, Merlino A
* γ-glutamyltranspeptidases: Sequence, structure, biochemical properties, and biotechnological applications (392 views)
Cell Mol Life Sci (ISSN: 1420-682x), 2012; 69(20): 3381-3394.
Impact Factor: 5.615
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Troise F, Monti M, Merlino A, Cozzolino F, Fedele C, Russo Krauss I, Sica F, Pucci P, D'Alessio G, De Lorenzo C
* A novel ErbB2 epitope targeted by human antitumor immunoagents (352 views)
Febs Journal (ISSN: 1742-464x), 2011 Apr; 278(7): 1156-1166.
Impact Factor: 3.79
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Lanzillo R, Orefice G, Prinster A, Ventrella G, Liuzzi R, Scarano V, Florio C, Vacca G, Brunetti A, Alfano B, Brescia Morra V, Bonavita V
* Predictive factors of neutralizing antibodies development in relapsing-remitting multiple sclerosis patients on interferon Beta-1b therapy (304 views) (PDF 218 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Apr; 32(2): 287-292.
Impact Factor: 1.315
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (381 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
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Castellano I, Di Salle A, Merlino A, Rossi M, La Cara F
* Gene cloning and protein expression of γ-glutamyltranspeptidases from Thermus thermophilus and Deinococcus radiodurans: Comparison of molecular and structural properties with mesophilic counterparts (302 views)
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic), 2011; 15(2): 259-270.
Impact Factor: 2.941
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Ruggiero A, Marasco D, Squeglia F, Soldini S, Pedone E, Pedone C, Berisio R
* Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (385 views)
Structure (ISSN: 0969-2126, 1878-4186, 0969-2126linking), 2010 Sep 8; 18(9): 1184-1190.
Impact Factor: 6.337
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Alterio V, Aurilia V, Romanelli A, Parracino A, Saviano M, D'Auria S, De Simone G
* Crystal structure of an S-formylglutathione hydrolase from pseudoalteromonas haloplanktis TAC125 (349 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 Sep; 93(8): 669-677.
Impact Factor: 2.572
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Turi I, Kállay C, Szikszai D, Pappalardo G, Di Natale G, De Bona P, Rizzarelli E, Sóvágó I
* Nickel(II) complexes of the multihistidine peptide fragments of human prion protein (468 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2010 Sep; 104(8): 885-891.
Impact Factor: 3.317
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Palmieri C, Falcone C, Iaccino E, Tuccillo FM, Gaspari M, Trimboli F, De Laurentiis A, Luberto L, Pontoriero M, Pisano A, Vecchio E, Fierro O, Panico M, Larobina M, Gargiulo S, Costa N, Dal Piaz F, Schiavone M, Arra C, Giudice A, Palma G, Barbieri A, Quinto I, Scala G
* In vivo targeting and growth inhibition of the A20 murine B-cell lymphoma by an idiotype-specific peptide binder (557 views)
Blood (ISSN: 0006-4971, 0006-6497, 0390-6078), 2010 Jul 15; 116(2): 226-238.
Impact Factor: 10.558
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La Mendola D, Magrì A, Campagna T, Campitiello MA, Raiola L, Isernia C, Hansson O, Bonomo RP, Rizzarelli E
* A doppel alpha-helix peptide fragment mimics the copper(II) interactions with the whole protein (1058 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2010 Jun 1; 16(21): 6212-6223.
Impact Factor: 5.476
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Castellano I, Merlino A, Rossi M, La Cara F
* Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity (586 views)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2010 May; 92(5): 464-474.
Impact Factor: 3.787
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Napolitano M, Ottaiano A, Mauro F, Ieranò C, Satriano R, Pacelli R, Franco R, De Angelis V, Castello G, Scala S
* CD4(+)CD45RA(+)CXCR4(+) lymphocytes are inversely associated with progression in stages I-III melanoma patients (351 views)
Cancer Immunol Immunother (ISSN: 0340-7004, 0340-7004linking), 2010 Apr; 59(4): 511-517.
Impact Factor: 4.293
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Kaczmarek K, Farina B, Zubrzak P, Jankowski S, Zimecki M, Suder P, Benedetti E, Fattorusso R, Saviano M, Zabrocki J
* Synthesis, conformational analysis and immunological activity of β3Phe-substituted Cyclolinopeptide A analogues (449 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 166-174.
Impact Factor: 1.807
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Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M
* Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity (443 views)
J Mol Biol (ISSN: 1089-8638, 0022-2836, 1089-8638electronic), 2009 Feb 6; 385(5): 1556-1567.
Impact Factor: 3.871
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Mandrich L, Menchise V, Alterio V, De Simone G, Pedone C, Rossi M, Manco G
* Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius (399 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2008 Jun; 71(4): 1721-1731.
Impact Factor: 3.419
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Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (436 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
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Saporito A, Marasco D, Chambery A, Botti P, Monti SM, Pedone C, Ruvo M
* The chemical synthesis of the GstI protein by NCL on a X-Met site (605 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2006 Dec 5; 83(5): 508-518.
Impact Factor: 2.48
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Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* A new spot test for sulfhydryl-containing compounds (432 views)
Anal Biochem, 2006 Mar 14; 79(1-2): 610-611.
Impact Factor: 2.305
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Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (654 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Mar 14; 45(10): 3226-3234.
Impact Factor: 3.633
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Cucinotta V, Giuffrida A, Maccarrone G, Messina M, Puglisi A, Rizzarelli E, Vecchio G
* Coordination properties of 3-functionalized β-cyclodextrins. Thermodynamic stereoselectivity of copper(II) complexes of the A, B-diamino derivative and its exploitation in LECE (347 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2005 Sep 21; (16): 2731-2736.
Impact Factor: 3.003
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Zubrzak P, Banas A, Kaczmarek K, Leplawy MT, Sochacki M, Kowalski ML, Szkudlinska B, Zabrocki J, Di Lello P, Isernia C, Saviano M, Pedone C, Benedetti E
* Analogues of cyclolinopeptide A containing alpha-hydroxymethyl amino acid residues (442 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2005; 80(2-3): 347-356.
Impact Factor: 2.425
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De Simone G, Mandrich L, Menchise V, Giordano V, Febbraio F, Rossi M, Pedone C, Manco G
* A substrate-induced switch in the reaction mechanism of a thermophilic esterase - Kinetic evidences and structural basis (381 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2004 Feb 20; 279(8): 6815-6823.
Impact Factor: 6.355
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Caridi A, Cufari A, Lovino R, Palumbo R, Tedesco I
* Influence of Yeast on Polyphenol Composition of Wine (227 views)
Food Technol Biotechnol (ISSN: 1330-9862), 2004 Jan; 42(1): 37-40.
Impact Factor: 0.475
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Mangiapia G, Accardo A, Celso FL, Tesauro D, Morelli G, Radulescu A, Paduano L
* Mixed micelles composed of peptides and gadolinium complexes as tumor-specific contrast agents in MRI: A sans study (563 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2004; 108(45): 17611-17617.
Impact Factor: 3.834
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Lombardi A, Nastri F, Marasco D, Maglio O, De Sanctis G, Sinibaldi F, Santucci R, Coletta M, Pavone V
* Design of a new mimochrome with unique topology (472 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2003 Nov 21; 9(22): 5643-5654.
Impact Factor: 4.353
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Galdiero M, Vitiello M, Galdiero S
* Eukaryotic cell signaling and transcriptional activation induced by bacterial porins (402 views)
Fems Microbiology Letters (ISSN: 0378-1097), 2003 Sep 12; 226(1): 57-64.
Impact Factor: 1.932
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De Simone G, Menchise V, Omaggio S, Pedone C, Scozzafava A, Supuran CT
* Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: Molecular and X-ray crystallographic studies (332 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2003 Sep 5; 42(30): 9013-9021.
Impact Factor: 3.922
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Formaggio F, Crisma M, Toniolo C, Broxterman QB, Kaptein B, Corbier C, Saviano M, Palladino P, Benedetti E
* Cα-Methyl, Cα-n-Propylglycine Homo-oligomers (292 views)
Macromolecules (ISSN: 0024-9297), 2003; 36(21): 8164-8170.
Impact Factor: 3.621
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Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (364 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
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Peggion C, Formaggio F, Crisma M, Toniolo C, Jimenez AI, Cativiela C, Kaptein B, Broxterman QB, Saviano M, Benedetti E
* Folding of peptides characterized by c3Val, a highly constrained analogue of valine (385 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003; 68(2): 178-191.
Impact Factor: 2.733
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Maglio O, Saldanha JW, Vrtala S, Spitzauer S, Valenta R, Pastore A
* A major IgE epitope-containing grass pollen allergen domain from Phl p 5 folds as a four-helix bundle (485 views)
Protein Eng (ISSN: 0269-2139print, 0269-2139linking), 2002 Aug; 15(8): 635-642.
Impact Factor: 2.126
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Renda A, Iovino F, Capasso L, Ricciardelli L, Tammaro V, Acampa W
Radioimmunoguided surgery in colorectal cancer: A 6-year experience with four different technical solutions (259 views)
Semin Surg Oncol Wiley Liss Inc (ISSN: 8756-0437), 1998 Dec; 15(4): 226-230.
Impact Factor: 1.045
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D'Andrea LD, Mazzeo M, Isernia C, Rossi F, Saviano M, Gallo P, Paolillo L, Pedone C
Solution conformational preferences of a peptidic analogue of a natural macrolide (357 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1997; 42(3): 349-361.
Impact Factor: 2.425
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Lombardi A, Saviano M, Nastri F, Maglio O, Mazzeo M, Pedone C, Isernia C, Pavone V
Unusual conformational preferences of β-alanine containing cyclic peptides. VII (450 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1996 Jun; 38(6): 683-691.
Impact Factor: 2.425
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Lombardi A, D'Auria G, Saviano M, Maglio O, Nastri F, Quartara L, Pedone C, Pavone V
Bicyclic Peptides As Type I/Type Ii Beta-Turn Scaffolds (504 views)
Biopolym Pept Sci Sect, 1996; 40(5): 505-518.
Impact Factor: 0
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Wink DA, Hanbauer I, Grisham MB, Laval F, Nims RW, Laval J, Cook J, Pacelli R, Liebmann J, Krishna M, Ford PC, Mitchell JB
Chemical biology of nitric oxide: Regulation and protective and toxic mechanisms (528 views)
Current Topics In Cellular Regulation (ISSN: 0070-2137), 1996; 34: 159-187.
Impact Factor: 4.375
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Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (359 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
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Rossi F, Saviano M, Di Talia P, Di Blasio B, Pedone C, Zanotti G, Mosca M, Saviano G, Tancredi T, Ziegler K, Benedetti E
Solution and solid state structure of an aib-containing cyclodecapeptide inhibiting the cholate uptake in hepatocytes (447 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1996; 40(5): 465-478.
Impact Factor: 2.425
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Pavone V, Lombardi A, Saviano M, Di Blasio B, Nastri F, Fattorusso R, Zaccaro L, Maglio O, Yamada T, Omote Y
Mixed conformation in C(α, α)-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-OMe and Bz-Dph-Dph-Gly-OMe (374 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1994 Dec; 34(12): 1595-1604.
Impact Factor: 2.425
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Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (225 views)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
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Zanotti G, Maione A, Rossi F, Saviano M, Pedone C, Tancredi T
BIOACTIVE PEPTIDES - CONFORMATIONAL STUDY OF A CYSTINYL CYCLOHEPTAPEPTIDE IN ITS FREE AND CALCIUM COMPLEXED FORMS (564 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1993 Jul; 33(7): 1083-1091.
Impact Factor: 2.425
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Di Blasio B, Lombardi A, D'Auria G, Saviano M, Isernia C, Maglio O, Paolillo L, Pedone C, Pavone V
Beta-Alanine Containing Peptides: Gamma-Turns In Cyclotetrapeptides (537 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1993 Apr; 31(10): 621-631.
Impact Factor: 2.425
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Della Ragione F, Oliva A, Palumbo R, Russo GL, Gragnaniello V, Zappia V
Deficiency of 5'-deoxy-5'-methylthioadenosine phosphorylase activity in malignancy. Absence of the protein in human enzyme-deficient cell lines (273 views)
Biochem J (ISSN: 0264-6021print, 0264-6021linking, 1470-8728electronic), 1992 Jan 15; 281(Pt2): 533-538.
Impact Factor: 3.579
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Del Vecchio S, Camera L, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Clinical studies with B72. 3 in ovarian cancer and probe-guided tumor localization (380 views)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1991; 18(1): 85-87.
Impact Factor: 1.042
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Della Ragione F, Oliva A, Gragnaniello V, Russo GL, Palumbo R, Zappia V
Physicochemical and immunological studies on mammalian 5'-deoxy-5'-methylthioadenosine phosphorylase (24 views) (PDF 7 views)
J Biol Chem (ISSN: 0021-9258linking), 1990 Apr 15; 265(11): 6241-6246.
Impact Factor: 5.328
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Steis RG, Carrasquillo JA, Mccabe R, Bookman MA, Reynolds JC, Larson SM, Smith JW, Clark JW, Dailey V, Del Vecchio S
Toxicity, immunogenicity, and tumor radioimmunodetecting ability of two human monoclonal antibodies in patients with metastatic colorectal carcinoma (283 views)
J Clin Oncol (ISSN: 0732-183x, 0732-183xlinking), 1990 Mar; 8(3): 476-490.
Impact Factor: 7.878
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Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (582 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
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Della Ragione F, Oliva A, Fioretti M, Russo GL, Palumbo R, Zappia V
Physico-chemical and immunological properties of bovine liver 5'-deoxy-5'-methylthioadenosine phosphorylase (472 views)
Adv Exp Med Biol (ISSN: 0065-2598print, 0065-2598linking), 1988; 250: 187-197.
Impact Factor: 0.36
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90 Records (89 excluding Abstracts).
Total impact factor: 336.439 (332.18 excluding Abstracts).
Total 5 year impact factor: 337.187 (332.34 excluding Abstracts).
Total impact factor: 336.439 (332.18 excluding Abstracts).
Total 5 year impact factor: 337.187 (332.34 excluding Abstracts).
459 views. Last view on Thursday 22 September 2022, 8:09:40
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