A straightforward synthetic access to symmetrical glycosyl disulfides and biological evaluation thereof (209 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2011 Sep 21; 9(18): 6278-6283.
Tipo di articolo: Journal Article,
Impact factor: 3.696, Impact factor a 5 anni: 3.652
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-80052216122&partnerID=40&md5=ad3176e16240b23c9685272708d99a51
Parole chiave: Biological Evaluation, Cytotoxic Activities, Glycosyl Disulfides, Human Tumor Cells, Sequential Approach, Synthetic Compounds, Cell Culture, Cytotoxicity, Selenium Compounds, Reaction Intermediates, Antineoplastic Agent, Article, Cell Survival, Chemistry, Drug Effect, Oxidation Reduction Reaction, Synthesis, Tumor Cell Line, Oxidation-Reduction,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Chimica Organica e Biochimica, Università Federico II di Napoli, via Cinthia 4, I-80126 Naples, Italy
Facoltà di Scienze Biotecnologiche, Università di Napoli Federico II, via Mezzocannone 16, 80134 Naples, Italy
Istituto di Biostrutture e Bioimmagini, CNR, via Mezzocannone 16, 80134 Naples, Italy
Facolt di Scienze Biotecnologiche, Universit di Napoli Federico II, via Mezzocannone 16, 80134 Naples, Italy
Riferimenti:
Pei, Z., Aastrup, T., Anderson, H., Ramström, O., (2005) Bioorg. Med. Chem. Lett., 15, p. 270
André, S., Pei, Z., Siebert, H.-C., Ramström, O., Gabius, H.-J., (2006) Bioorg. Med. Chem., 14, p. 6314
Pei, Z., Larsson, R., Aastrup, T., Anderson, H., Lehn, J.-M., Ramström, O., (2006) Biosens. Bioelectron., 22, p. 42
Caraballo, R., Sakulsombat, M., Ramström, O., (2010) Chem. Commun., 46, p. 8469
Richtmyer, N.K., Carr, C.J., Hudson, C.S., (1943) J. Am. Chem. Soc., 65, p. 1477
Cerny, M., Vrkoc, J., Stanek, J., (1959) Collect. Czech. Chem. Commun., 24, p. 64
Horton, D., (1963) Methods Carbohydr. Chem., 2, p. 433
Kiefel, M.J., Thomson, R.J., Radovanovic, M., Von Itzstein, M., (1999) J. Carbohydr. Chem., 18, p. 937
Knapp, S., Darout, E., Amorelli, B., (2006) J. Org. Chem., 71, p. 1380
Floyd, N., Vijayakrishnan, B., Koeppe, A.R., Davis, B.G., (2009) Angew. Chem., Int. Ed., 48, p. 7798
Bhar, D., Chandrasekaran, S., (1997) Carbohydr. Res., 301, p. 221
Szilagy, L., Illyes, T.-Z., Herczegh, P., (2001) Tetrahedron Lett., 42, p. 3901
Davis, B.G., Ward, S.J., Rendle, P.M., (2001) Chem. Commun., p. 189
Ribeiro Morais, G., Falconer, R.A., (2007) Tetrahedron Lett., 48, p. 7637
Aversa, M.C., Barattucci, A., Bonaccorsi, P., (2009) Eur. J. Org. Chem., p. 6455
Stellenboom, N., Hunter, R., Caira, M.R., Szilagy, L., (2010) Tetrahedron Lett., 51, p. 5309
Valerio, S., Iadonisi, A., Adinolfi, M., Ravidà, A., (2007) J. Org. Chem., 72, p. 6097
Adinolfi, M., Iadonisi, A., Ravidà, A., Schiattarella, M., (2003) Tetrahedron Lett., 44, p. 7863
Ibatullin, F.M., Selivanov, S.I., Shavva, A.G., (2001) Synthesis, p. 419
Pezzella, A., Iadonisi, A., Valerio, S., Panzella, L., Napolitano, A., Adinolfi, M., D'Ischia, M., (2009) J. Am. Chem. Soc., 131, p. 15270. , For a stepwise approach to (phenylselenyl)thioglycosides and their application to protein glycoconjugation via disulfide linkage
Gamblin, D.P., Garnier, P., Van Kasteren, S., Oldham, N.J., Fairbanks, A.J., Davis, B.G., (2004) Angew. Chem., Int. Ed., 43, p. 828. , For a recent kinetic study on the formation of disulfide and SSe linkages
Steinmann, D., Nauser, T., Koppenol, W.H., (2010) J. Org. Chem., 75, p. 6696
Sharpless, K.B., Young, M.W., (1975) J. Org. Chem., 40, p. 947
Smith Iii, A.B., Richmond, R.E., (1983) J. Am. Chem. Soc., 105, p. 575
Huang, X., Liu, X., Luo, Q., Liu, J., Shen, J., (2011) Chem. Soc. Rev., 40, p. 1171
Rajanbabu, T.V., Ayers, T.A., Halliday, G.A., You, K.K., Calabrese, J.C., (1997) J. Org. Chem., 62, p. 6012
Miquel, N., Vignando, S., Russo, G., Lay, L., (2004) Synlett, 341
Hummel, G., Hindsgaul, O., (1999) Angew. Chem., Int. Ed., 38, p. 1782
Martins Alho, M.A., D'Accorso, N.B., Thiel, I.M.E., (1996) J. Heterocycl. Chem., 33, p. 1339
Renaudie, L., Daniellou, R., Augè, C., Le Narvor, C., (2004) Carbohydr. Res., 339, p. 693
Gillies, R.G., Didier, N., Denton, M., (1986) Anal. Biochem., 159, p. 109
Andr, S., Pei, Z., Siebert, H. -C., Ramstr m, O., Gabius, H. -J., (2006) Bioorg. Med. Chem., 14, p. 6314
Richtmyer, N. K., Carr, C. J., Hudson, C. S., (1943) J. Am. Chem. Soc., 65, p. 1477
Kiefel, M. J., Thomson, R. J., Radovanovic, M., Von Itzstein, M., (1999) J. Carbohydr. Chem., 18, p. 937
Davis, B. G., Ward, S. J., Rendle, P. M., (2001) Chem. Commun., p. 189
Aversa, M. C., Barattucci, A., Bonaccorsi, P., (2009) Eur. J. Org. Chem., p. 6455
Ibatullin, F. M., Selivanov, S. I., Shavva, A. G., (2001) Synthesis, p. 419
Gamblin, D. P., Garnier, P., Van Kasteren, S., Oldham, N. J., Fairbanks, A. J., Davis, B. G., (2004) Angew. Chem., Int. Ed., 43, p. 828. , For a recent kinetic study on the formation of disulfide and SSe linkages
Sharpless, K. B., Young, M. W., (1975) J. Org. Chem., 40, p. 947
Smith Iii, A. B., Richmond, R. E., (1983) J. Am. Chem. Soc., 105, p. 575
Rajanbabu, T. V., Ayers, T. A., Halliday, G. A., You, K. K., Calabrese, J. C., (1997) J. Org. Chem., 62, p. 6012
Martins Alho, M. A., D'Accorso, N. B., Thiel, I. M. E., (1996) J. Heterocycl. Chem., 33, p. 1339
Gillies, R. G., Didier, N., Denton, M., (1986) Anal. Biochem., 159, p. 109
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2011 Sep 21; 9(18): 6278-6283.
Tipo di articolo: Journal Article,
Impact factor: 3.696, Impact factor a 5 anni: 3.652
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-80052216122&partnerID=40&md5=ad3176e16240b23c9685272708d99a51
Parole chiave: Biological Evaluation, Cytotoxic Activities, Glycosyl Disulfides, Human Tumor Cells, Sequential Approach, Synthetic Compounds, Cell Culture, Cytotoxicity, Selenium Compounds, Reaction Intermediates, Antineoplastic Agent, Article, Cell Survival, Chemistry, Drug Effect, Oxidation Reduction Reaction, Synthesis, Tumor Cell Line, Oxidation-Reduction,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Chimica Organica e Biochimica, Università Federico II di Napoli, via Cinthia 4, I-80126 Naples, Italy
Facoltà di Scienze Biotecnologiche, Università di Napoli Federico II, via Mezzocannone 16, 80134 Naples, Italy
Istituto di Biostrutture e Bioimmagini, CNR, via Mezzocannone 16, 80134 Naples, Italy
Facolt di Scienze Biotecnologiche, Universit di Napoli Federico II, via Mezzocannone 16, 80134 Naples, Italy
Riferimenti:
Pei, Z., Aastrup, T., Anderson, H., Ramström, O., (2005) Bioorg. Med. Chem. Lett., 15, p. 270
André, S., Pei, Z., Siebert, H.-C., Ramström, O., Gabius, H.-J., (2006) Bioorg. Med. Chem., 14, p. 6314
Pei, Z., Larsson, R., Aastrup, T., Anderson, H., Lehn, J.-M., Ramström, O., (2006) Biosens. Bioelectron., 22, p. 42
Caraballo, R., Sakulsombat, M., Ramström, O., (2010) Chem. Commun., 46, p. 8469
Richtmyer, N.K., Carr, C.J., Hudson, C.S., (1943) J. Am. Chem. Soc., 65, p. 1477
Cerny, M., Vrkoc, J., Stanek, J., (1959) Collect. Czech. Chem. Commun., 24, p. 64
Horton, D., (1963) Methods Carbohydr. Chem., 2, p. 433
Kiefel, M.J., Thomson, R.J., Radovanovic, M., Von Itzstein, M., (1999) J. Carbohydr. Chem., 18, p. 937
Knapp, S., Darout, E., Amorelli, B., (2006) J. Org. Chem., 71, p. 1380
Floyd, N., Vijayakrishnan, B., Koeppe, A.R., Davis, B.G., (2009) Angew. Chem., Int. Ed., 48, p. 7798
Bhar, D., Chandrasekaran, S., (1997) Carbohydr. Res., 301, p. 221
Szilagy, L., Illyes, T.-Z., Herczegh, P., (2001) Tetrahedron Lett., 42, p. 3901
Davis, B.G., Ward, S.J., Rendle, P.M., (2001) Chem. Commun., p. 189
Ribeiro Morais, G., Falconer, R.A., (2007) Tetrahedron Lett., 48, p. 7637
Aversa, M.C., Barattucci, A., Bonaccorsi, P., (2009) Eur. J. Org. Chem., p. 6455
Stellenboom, N., Hunter, R., Caira, M.R., Szilagy, L., (2010) Tetrahedron Lett., 51, p. 5309
Valerio, S., Iadonisi, A., Adinolfi, M., Ravidà, A., (2007) J. Org. Chem., 72, p. 6097
Adinolfi, M., Iadonisi, A., Ravidà, A., Schiattarella, M., (2003) Tetrahedron Lett., 44, p. 7863
Ibatullin, F.M., Selivanov, S.I., Shavva, A.G., (2001) Synthesis, p. 419
Pezzella, A., Iadonisi, A., Valerio, S., Panzella, L., Napolitano, A., Adinolfi, M., D'Ischia, M., (2009) J. Am. Chem. Soc., 131, p. 15270. , For a stepwise approach to (phenylselenyl)thioglycosides and their application to protein glycoconjugation via disulfide linkage
Gamblin, D.P., Garnier, P., Van Kasteren, S., Oldham, N.J., Fairbanks, A.J., Davis, B.G., (2004) Angew. Chem., Int. Ed., 43, p. 828. , For a recent kinetic study on the formation of disulfide and SSe linkages
Steinmann, D., Nauser, T., Koppenol, W.H., (2010) J. Org. Chem., 75, p. 6696
Sharpless, K.B., Young, M.W., (1975) J. Org. Chem., 40, p. 947
Smith Iii, A.B., Richmond, R.E., (1983) J. Am. Chem. Soc., 105, p. 575
Huang, X., Liu, X., Luo, Q., Liu, J., Shen, J., (2011) Chem. Soc. Rev., 40, p. 1171
Rajanbabu, T.V., Ayers, T.A., Halliday, G.A., You, K.K., Calabrese, J.C., (1997) J. Org. Chem., 62, p. 6012
Miquel, N., Vignando, S., Russo, G., Lay, L., (2004) Synlett, 341
Hummel, G., Hindsgaul, O., (1999) Angew. Chem., Int. Ed., 38, p. 1782
Martins Alho, M.A., D'Accorso, N.B., Thiel, I.M.E., (1996) J. Heterocycl. Chem., 33, p. 1339
Renaudie, L., Daniellou, R., Augè, C., Le Narvor, C., (2004) Carbohydr. Res., 339, p. 693
Gillies, R.G., Didier, N., Denton, M., (1986) Anal. Biochem., 159, p. 109
Andr, S., Pei, Z., Siebert, H. -C., Ramstr m, O., Gabius, H. -J., (2006) Bioorg. Med. Chem., 14, p. 6314
Richtmyer, N. K., Carr, C. J., Hudson, C. S., (1943) J. Am. Chem. Soc., 65, p. 1477
Kiefel, M. J., Thomson, R. J., Radovanovic, M., Von Itzstein, M., (1999) J. Carbohydr. Chem., 18, p. 937
Davis, B. G., Ward, S. J., Rendle, P. M., (2001) Chem. Commun., p. 189
Aversa, M. C., Barattucci, A., Bonaccorsi, P., (2009) Eur. J. Org. Chem., p. 6455
Ibatullin, F. M., Selivanov, S. I., Shavva, A. G., (2001) Synthesis, p. 419
Gamblin, D. P., Garnier, P., Van Kasteren, S., Oldham, N. J., Fairbanks, A. J., Davis, B. G., (2004) Angew. Chem., Int. Ed., 43, p. 828. , For a recent kinetic study on the formation of disulfide and SSe linkages
Sharpless, K. B., Young, M. W., (1975) J. Org. Chem., 40, p. 947
Smith Iii, A. B., Richmond, R. E., (1983) J. Am. Chem. Soc., 105, p. 575
Rajanbabu, T. V., Ayers, T. A., Halliday, G. A., You, K. K., Calabrese, J. C., (1997) J. Org. Chem., 62, p. 6012
Martins Alho, M. A., D'Accorso, N. B., Thiel, I. M. E., (1996) J. Heterocycl. Chem., 33, p. 1339
Gillies, R. G., Didier, N., Denton, M., (1986) Anal. Biochem., 159, p. 109
Symmetrical glycosyl disulfides can be prepared within a few hours from per-O-acetylated precursors via a sequential approach entailing short reactions and no purification of any intermediate. The final thiolate-to-disulfide oxidation step is noticeably accelerated by low amounts of phenyl diselenide under air. Applicability of the strategy to non-saccharidic symmetrical alkyl disulfides has also been examined. A preliminary assay of the cytotoxic activity of symmetrical 1,1'-disulfides was performed on two human tumor cell lines, and a noteworthy activity was recorded for a range of these synthetic compounds.
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* Age-related impairment in insulin release: The essential role of β 2-adrenergic receptor (253 visite)
Diabetesdiabetes (ISSN: 0012-1797), 2012; 61(3): 692-701.
Impact Factor: 7.895
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Sorriento D, Santulli G, Del Giudice C, Anastasio A, Trimarco B, Iaccarino G
* Endothelial cells are able to synthesize and release catecholamines both in vitro and in vivo (258 visite)
Hypertensionhypertension (ISSN: 0194-911x), 2012; 60(1): 129-136.
Impact Factor: 6.873
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Folgiero V, Di Carlo SE, Bossi G, Spugnini E, Di Benedetto A, Bon G, Milella M, Fabi A, Accardo A, Morelli G, Mottolese M, Falcioni R
* Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells (243 visite)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2012; 3(12): N/D-N/D.
Impact Factor: 6.044
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Fusco A, Santulli G, Sorriento D, Cipolletta E, Garbi C, Dorn GW, Trimarco B, Feliciello A, Iaccarino G
* Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis (196 visite)
Cell Signal (ISSN: 0898-6568), 2012; 24(2): 468-475.
Impact Factor: 4.304
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Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (214 visite)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
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Satriano C, Fragalà ME, Forte G, Santoro AM, La Mendola D, Kasemo B
* Surface adsorption of fibronectin-derived peptide fragments: The influence of electrostatics and hydrophobicity for endothelial cells adhesion (162 visite)
Soft Matter (ISSN: 1744-683x), 2012; 8(1): 53-56.
Impact Factor: 3.909
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Roviello GN, Ricci A, Bucci EM, Pedone C
* Synthesis, biological evaluation and supramolecular assembly of novel analogues of peptidyl nucleosides (559 visite)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1773-1778.
Impact Factor: 3.534
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Travaglia A, Arena G, Fattorusso R, Isernia C, La Mendola D, Malgieri G, Nicoletti VG, Rizzarelli E
* The inorganic perspective of nerve growth factor: interactions of Cu2+ and Zn2+ with the N-terminus fragment of nerve growth factor encompassing the recognition domain of the TrkA receptor (255 visite)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Mar 21; 17(13): 3726-3738.
Impact Factor: 5.925
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Accardo A, Morisco A, Palladino P, Palumbo R, Tesauro D, Morelli G
* Amphiphilic CCK peptides assembled in supramolecular aggregates: Structural investigations and in vitro studies (271 visite)
Mol Biosyst (ISSN: 1742-206x), 2011 Mar; 7(3): 862-870.
Impact Factor: 3.534
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Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, Copani A, Nicoletti F
* Targeting group II Metabotropic Glutamate (mGlu) receptors for the treatment of psychosis associated with alzheimer's disease: Selective activation of mGlu2 receptors amplifies β-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective (424 visite)
Mol Pharmacol (ISSN: 0026-895x), 2011 Mar; 79(3): 618-626.
Impact Factor: 4.883
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Santulli G, Basilicata MF, De Simone M, Del Giudice C, Anastasio A, Sorriento D, Saviano M, Del Gatto A, Trimarco B, Pedone C, Zaccaro L, Iaccarino G
* Evaluation of the anti-angiogenic properties of the new selective alphaVbeta3 integrin antagonist RGDechiHCit (280 visite)
J Transl Med Journal Of Translational Medicine (ISSN: 1479-5876electronic), 2011 Jan 13; 9: 7-7.
Impact Factor: 3.474
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Morisco A, Accardo A, Tesauro D, Palumbo R, Benedetti E, Morelli G
* Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (214 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011; 96(1): 88-96.
Impact Factor: 2.87
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Fantini D, Vascotto C, Marasco D, D'Ambrosio C, Romanello M, Vitagliano L, Pedone C, Poletto M, Cesaratto L, Quadrifoglio F, Scaloni A, Radicella JP, Tell G
* Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions (178 visite)
Nucleic Acids Res (ISSN: 1362-4962, 0305-1048, 1362-4962electronic), 2010 Dec; 38(22): 8239-8256.
Impact Factor: 7.836
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Digilio G, Menchise V, Gianolio E, Catanzaro V, Carrera C, Napolitano R, Fedeli F, Aime S
* Exofacial protein thiols as a route for the internalization of Gd(III)-based complexes for magnetic resonance imaging cell labeling (274 visite)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jul 8; 53(13): 4877-4890.
Impact Factor: 5.207
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Alfieri A, Pasanisi F, Salzano S, Esposito L, Martone D, Tafuri D, Daniele A, Contaldo F, Sacchetti L, Zagari A, Buono P
* Functional analysis of melanocortin-4-receptor mutants identified in severely obese subjects living in Southern Italy (223 visite)
Gene (ISSN: 0378-1119), 2010 Jun 1; 457(1-2): 35-41.
Impact Factor: 2.266
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Tosco A, Monti MC, Fontanella B, Montefusco S, D'Andrea LD, Ziaco B, Baldantoni D, Rio MC, Marzullo L
* Copper binds the carboxy-terminus of trefoil protein 1 (TFF1), favoring its homodimerization and motogenic activity (221 visite)
Cell Mol Life Sci (ISSN: 1420-9071electronic, 1420-682xlinking), 2010 Jun; 67(11): 1943-1955.
Impact Factor: 7.047
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Kelly SE, Di Benedetto A, Greco A, Howard CM, Sollars VE, Primerano DA, Valluri JV, Claudio PP
* Rapid Selection and Proliferation of CD133(+) Cells from Cancer Cell Lines: Chemotherapeutic Implications (216 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2010 Apr 8; 5(4): N/D-N/D.
Impact Factor: 4.411
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Satriano C, Messina GM, Marino C, Aiello I, Conte E, La Mendola D, Distefano DA, D'Alessandro F, Pappalardo G, Impellizzeri G
* Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films - Effects on fibroblast spreading (314 visite)
J Colloid Interface Sci (ISSN: 1095-7103electronic, 0021-9797linking), 2010 Jan 15; 341(2): 232-239.
Impact Factor: 3.068
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Di Stasi R, Diana D, Capasso D, Palumbo R, Romanelli A, Pedone C, Fattorusso R, D'Andrea LD
* VEGFR1(D2) in drug discovery: Expression and molecular characterization (181 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010; 94(6): 800-809.
Impact Factor: 2.572
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Carriero MV, Longanesi-cattani I, Bifulco K, Maglio O, Lista L, Barbieri A, Votta G, Masucci MT, Arra C, Franco R, De Rosa M, Stoppelli MP, Pavone V
* Structure-based design of an urokinase-type plasminogen activator receptor-derived peptide inhibiting cell migration and lung metastasis (245 visite)
Mol Cancer Ther (ISSN: 1535-7163, 1538-8514electronic, 1535-7163linking), 2009 Sep; 8(9): 2708-2717.
Impact Factor: 4.953
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Ierano C, Giuliano P, D'Alterio C, Cioffi M, Mettivier V, Portella L, Napolitano M, Barbieri A, Arra C, Liguori G, Franco R, Palmieri G, Rozzo C, Pacelli R, Castello G, Scala S
* A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration (229 visite)
Cell Cycle (ISSN: 1538-4101), 2009 Apr 15; 8(8): 1228-1237.
Impact Factor: 4.087
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De Bona P, Giuffrida ML, Caraci F, Copani A, Pignataro B, Attanasio F, Cataldo S, Pappalardo G, Rizzarelli E
* Design And Synthesis Of New Trehalose-Conjugated Pentapeptides As Inhibitors Of Abeta (1-42) Fibrillogenesis And Toxicity (342 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 220-228.
Impact Factor: 1.807
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Lettieri A, Salvatore M
* Molecular imaging of drug resistance in cancer (262 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Mar; 21(1): 31-36.
Impact Factor: 0.268
Dettagli Esporta in BibTeX Esporta in EndNote
Sorriento D, Campanile A, Santulli G, Leggiero E, Pastore L, Trimarco B, Iaccarino G
* A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity (182 visite)
Mol Cancermolecular Cancer (ISSN: 1476-4598), 2009; 8: N/D-N/D.
Impact Factor: 4.16
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Hilvo M, Baranauskiene L, Salzano AM, Scaloni A, Matulis D, Innocenti A, Scozzafava A, Monti SM, Di Fiore A, De Simone G, Lindfors M, Janis J, Valjakka J, Pastorekova S, Pastorek J, Kulomaa MS, Nordlund HR, Supuran CT, Parkkila S
* Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes (253 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Oct 10; 283(41): 27799-27809.
Impact Factor: 5.52
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Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M
* Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells (240 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Sep 1; 283(31): 21769-21778.
Impact Factor: 5.52
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Castiglione M, Calafiore M, Costa L, Sortino MA, Nicoletti F, Copani A
* Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice (235 visite)
Neuropharm (ISSN: 0028-3908, 1873-7064electronic, 0028-3908linking), 2008 Sep; 55(4): 560-567.
Impact Factor: 3.383
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Guarnieri D, Borzacchiello A, De Capua A, Ruvo M, Netti P
* Engineering of covalently immobilized gradients of RGD peptides on hydrogel scaffolds: Effect on cell behaviour (218 visite)
Macromol Sympos (ISSN: 1022-1360), 2008; 266(1): 36-40.
Impact Factor: 0
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Sorriento D, Ciccarelli M, Santulli G, Campanile A, Altobelli GG, Cimini V, Galasso G, Astone D, Piscione F, Pastore L, Trimarco B, Iaccarino G
* The G-protein-coupled receptor kinase 5 inhibits NFκB transcriptional activity by inducing nuclear accumulation of IκBα (205 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2008; 105(46): 17818-17823.
Impact Factor: 9.38
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Nicoletti VG, Santoro AM, Grasso G, Vagliasindi LI, Giuffrida ML, Cuppari C, Purrello VS, Stella AMG, Rizzarelli E
* Carnosine interaction with nitric oxide and astroglial cell protection (373 visite)
Journal Of Neuroscience Research (ISSN: 0360-4012), 2007 Sep 1; 85(10): 2239-2245.
Impact Factor: 3.268
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De Luca S, De Capua A, Saviano M, Della Moglie R, Aloj L, Tarallo L, Pedone C, Morelli G
* Synthesis and biological evaluation of cyclic and branched peptide analogues as ligands for cholecystokinin type 1 receptor (201 visite)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 1464-3391electronic), 2007 Sep 1; 15(17): 5845-5853.
Impact Factor: 2.662
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Ragno R, Simeoni S, Castellano S, Vicidomini C, Mai A, Caroli A, Tramontano A, Bonaccini C, Trojer P, Bauer I, Brosch G, Sbardella G
* Small molecule inhibitors of histone arginine methyltransferases: Homology modeling, molecular docking, binding mode analysis, and biological evaluations (243 visite)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2007 Mar 22; 50(6): 1241-1253.
Impact Factor: 4.895
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Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T
* Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage (220 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2007 Jan 12; 282(2): 831-835.
Impact Factor: 5.581
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Dalla Bona A, Formaggio F, Peggion C, Kaptein B, Broxterman Quirinus B, Galdiero S, Galdiero M, Vitiello M, Benedetti E, Toniolo C
* Synthesis, conformation, and bioactivity of novel analogues of the antiviral lipopeptide halovir (194 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 748-757.
Impact Factor: 1.801
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Galdiero S, Falanga A, Vitiello M, Browne H, Pedone C, Galdiero M
* Fusogenic domains in herpes simplex virus type 1 glycoprotein (247 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Sep 5; 280(31): 28632-28643.
Impact Factor: 5.854
Dettagli Esporta in BibTeX Esporta in EndNote
Calabrese V, Colombrita C, Guagliano E, Sapienza M, Ravagna A, Cardile V, Scapagnini G, Santoro AM, Mangiameli A, Butterfield DA, Giuffrida Stella AM, Rizzarelli E
* Protective effect of carnosine during nitrosative stress in astroglial cell cultures (193 visite)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2005 Jun; 30(6-7): 797-807.
Impact Factor: 2.187
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Cozzolino R, Palladino P, Rossi F, Cali G, Benedetti E, Laccetti P
* Antineoplastic cyclic astin analogues kill tumour cells via caspase-mediated induction of apoptosis (254 visite)
Carcinogenesis (ISSN: 0143-3334), 2005 Apr; 26(4): 733-739.
Impact Factor: 5.108
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Paesano N, Marzocco S, Vicidomini C, Saturnino C, Autore G, De Martino G, Sbardella G
* Synthesis and biological evaluation of 3-benzyl-1-methyl- and 1-methyl-3-phenyl-isothioureas as potential inhibitors of iNOS (251 visite)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2005 Feb 1; 15(3): 539-543.
Impact Factor: 2.478
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Tedesco I, Nappo A, Petitto F, Iacomino G, Nazzaro F, Palumbo R, Russo Gian L
* Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line (222 visite)
Nutr Cancer (ISSN: 0163-5581), 2005; 52(1): 74-83.
Impact Factor: 2.426
Dettagli Esporta in BibTeX Esporta in EndNote
Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R
* Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter (207 visite)
Oncology Research (ISSN: 0965-0407), 2005; 15(7-8): 373-383.
Impact Factor: 1.844
Dettagli Esporta in BibTeX Esporta in EndNote
Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (176 visite)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
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Iaccarino G, Ciccarelli M, Sorriento D, Galasso G, Campanile A, Santulli G, Cipolletta E, Cerullo V, Cimini V, Altobelli GG, Piscione F, Priante O, Pastore L, Chiariello M, Salvatore F, Koch WJ, Trimarco B
* Ischemic neoangiogenesis enhanced by β2-adrenergic receptor overexpression: A novel role for the endothelial adrenergic system (200 visite)
Circ Res (ISSN: 0009-7330, 1524-4571electronic), 2005; 97(11): 1182-1189.
Impact Factor: 9.408
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Filippo C, Mariangela C, Giuseppina F, Pier Luigi C, Angelo B, Marco C, Giuseppe B, Paolo B, Ferdinando N, Agata C, Maria Angela S
* Nicergoline, a drug used for age-dependent cognitive impairment, protects cultured neurons against β-amyloid toxicity (460 visite)
Brain Res (ISSN: 0006-8993), 2005; 1047(1): 30-37.
Impact Factor: 2.296
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Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R
* Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression (214 visite)
Curr Drug Targets (ISSN: 1389-4501), 2004 Nov; 5(8): 735-744.
Impact Factor: 4.104
Dettagli Esporta in BibTeX Esporta in EndNote
Penolazzi L, Borgatti M, Lambertini E, Mischiati C, Finotti A, Romanelli A, Saviano M, Pedone C, Piva R, Gambari R
* Peptide nucleic acid-DNA decoy chimeras targeting NF-kappa B transcription factors: Induction of apoptosis in human primary osteoclasts (190 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2004 Sep; 14(2): 145-152.
Impact Factor: 3.19
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Caricasole A, Copani A, Caraci F, Aronica E, Rozemuller AJ, Caruso A, Storto M, Gaviraghi G, Terstappen GC, Nicoletti F
* Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain (285 visite)
J Neurosci (ISSN: 0270-6474, 0361-803x, 1529-2401), 2004 Jun 30; 24(26): 6021-6027.
Impact Factor: 2.384
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Aloj L, Panico M, Caraco C, Del Vecchio S, Arra C, Affuso A, Accardo A, Mansi R, Tesauro D, De Luca S, Pedone C, Visentin R, Mazzi U, Morelli G, Salvatore M
* In vitro and in vivo characterization of Indium-111 and Technetium-99m labeled CCK-8 derivatives for CCK-B receptor imaging (265 visite)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2004 Feb; 19(1): 93-98.
Impact Factor: 1.091
Dettagli Esporta in BibTeX Esporta in EndNote
Rossi F, Zanotti G, Saviano M, Iacovino R, Palladino P, Saviano G, Amodeo P, Tancredi T, Laccetti P, Corbier C, Benedetti E
* New antitumour cyclic astin analogues: Synthesis, conformation and bioactivity (239 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2004 Feb; 10(2): 92-102.
Impact Factor: 1.652
Dettagli Esporta in BibTeX Esporta in EndNote
Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C
* Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles (225 visite)
The Aaps Journal (ISSN: 1522-1059, 1550-7416), 2004 Jan 20; 6(1): N/D-N/D.
Impact Factor: 1.938
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Spalletti-cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M
* Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis (195 visite)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2003 Jun; 88(6): 2900-2907.
Impact Factor: 5.873
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Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (201 visite)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
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Cardone L, de Cristofaro T, Affaitati A, Garbi C, Ginsberg MD, Saviano M, Varrone S, Rubin CS, Gottesman ME, Avvedimento EV, Feliciello A
* A-kinase anchor protein 84/121 are targeted to mitochondria and mitotic spindles by overlapping amino-terminal motifs (184 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2002 Jul 12; 320(3): 663-675.
Impact Factor: 5.359
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De Falco S, Ruvoletto MG, Verdoliva A, Ruvo M, Raucci A, Marino M, Senatore S, Cassani G, Alberti A, Pontisso P, Fassina G
* Cloning and Expression of a Novel Hepatitis B Virus-binding Protein from HepG2 Cells (251 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2001 Sep 28; 276(39): 36613-36623.
Impact Factor: 7.258
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Fonti R, Levchenko A, Mehta BM, Zhang J, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in human neuroblastoma xenografts using in vitro quantitative autoradiography (164 visite)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999 Jan; 26(1): 35-41.
Impact Factor: 1.623
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Fonti R, Cheung N-KV, Bridger GJ, Guo H-F, Abrams MJ, Larson SM
99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors (189 visite)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999; 26(6): 681-686.
Impact Factor: 1.623
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Cook JA, Krishna MC, Pacelli R, DeGraff W, Liebmann J, Mitchell JB, Russo A, Wink DA
Nitric oxide enhancement of melphalan-induced cytotoxicity (205 visite)
Br J Cancer (ISSN: 0007-0920, 0007-0920print, 0007-0920linking), 1997 Sep; 76(3): 325-334.
Impact Factor: 2.938
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Li PY, Del Vecchio S, Fonti R, Carriero MV, Potena MI, Botti G, Miotti S, Lastoria S, Menard S, Colnaghi MI, Salvatore M
Local concentration of folate binding protein GP38 in sections of human ovarian carcinoma by in vitro quantitative autoradiography (250 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 Apr; 37(4-6): 665-672.
Impact Factor: 3.491
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Latella G, Fonti R, Caprilli R, Marcheggiano A, Magliocca F, Das KM, Gambús G, Sambuy Y
Characterization of the mucins produced by normal human colonocytes in primary culture (162 visite)
International Journal Of Colorectal Disease (ISSN: 0179-1958, 0179-1958linking), 1996; 11(2): 76-83.
Impact Factor: 0.732
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Miles AM, Gibson MF, Kirshina M, Cook JC, Pacelli R, Wink D, Grisham MB
Effects of superoxide on nitric oxide-dependent n-nitrosation reactions (144 visite)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 1995 Oct; 23(4): 379-390.
Impact Factor: 2.361
Dettagli Esporta in BibTeX Esporta in EndNote
Fonti R, Latella G, Bises G, Magliocca F, Nobili F, Caprilli R, Sambuy Y
Human colonocytes in primary culture: a model to study epithelial growth, metabolism and differentiation (186 visite)
International Journal Of Colorectal Disease (ISSN: 0179-1958, 0179-1958linking), 1994; 9(1): 13-22.
Impact Factor: 0.732
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Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (169 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
Dettagli Esporta in BibTeX Esporta in EndNote
Trischitta V, Wong KY, Brunetti A, Scalisi R, Vigneri R, Goldfine ID
Endocytosis, recycling, and degradation of the insulin receptor. Studies with monoclonal antireceptor antibodies that do not activate receptor kinase (151 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 1989 Mar 25; 264(9): 5041-5046.
Impact Factor: 6.963
Dettagli Esporta in BibTeX Esporta in EndNote
Ferrara LA, Soro S, Marotta T, Mancini M
Chronobiological Evaluation Of Cardiovascular Reactivity (163 visite)
Atherosclerosis And Cardiovascular Disease Descovich G C Gaddi A Magri Gl Lenzi S, 1989; 4(a): 10-10.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Purrello F, Gullo D, Brunetti A, Buscema M, Italia S, Goldfine ID, Vigneri R
Direct effects of biguanides on glucose utilization in vitro (119 visite)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1987 Sep; 36(8): 774-776.
Impact Factor: 1.681
Dettagli Esporta in BibTeX Esporta in EndNote
88 Records (82 escludendo Abstract e Conferenze).
Impact factor totale: 347.772 (327.32 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 360.309 (336.443 escludendo Abstract e Conferenze).
Impact factor totale: 347.772 (327.32 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 360.309 (336.443 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
Ultima modifica di Marco Comerci in data Thursday 19 March 2015, 16:43:14
209 visite. Ultima visita in data Sunday 16 February 2020, 3:13:45
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