99mTc sestamibi cardiac tomography and dobutamine echocardiography in the identification of reversible left ventricular dysfunction in patients with acute myocardial infarction(85 visite) Gisonni P, Cuocolo A, Spinelli L, Acampa W, Florimonte L, Nicolai E, Petretta M, Sodano A
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1999 Apr; 97(4): 265-270.
Tipo di articolo: Journal Article,
Impact factor: 0.967, Impact factor a 5 anni: 1.448
Centro de la Med. Nucleare del CNR, Universita Federico II, Via Pansini 5, 80131 Napoli NA, Italy
Introduction. We investigated the role of technetium-99m (99mTc) sestamibi cardiac imaging and dobutamine echocardiography in detecting myocardial viability early after acute myocardial infarction. Material and methods. Nineteen patients (mean age 52 ± 10 years) underwent coronary angiography, low-dose dobutamine echocardiography and rest 99mTc sestamibi imaging within 10 days of myocardial infarction. All patients were revascularized. Resting echocardiogram was repeated 8 months later to evaluate segmental functional recovery. Results. Sixty-one of 108 akinetic or dyskinetic segments at baseline showed functional recovery after revascularization. Sensitivity in predicting segmental functional recovery was 87% for sestamibi imaging and 66% for dobutamine echocardiography (p < 0.001), while specificity and accuracy were comparable. Sestamibi activity was the strongest predictor of segmental functional recovery (p < 0.001). Conclusions. Dobutamine echocardiography predicts functional recovery after myocardial infarction. However, sestamibi imaging is useful to identify patients with dysfunctional segments without contractile reserve which may benefit by revascularization.
126 Records (105 escludendo Abstract e Conferenze). Impact factor totale: 382.398 (295.911 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 471.989 (354.698 escludendo Abstract e Conferenze).