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99mTc sestamibi cardiac tomography and dobutamine echocardiography in the identification of reversible left ventricular dysfunction in patients with acute myocardial infarction (73 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1999 Apr; 97(4): 265-270.
Tipo di articolo: Journal Article,
Impact factor: 0.967
Impact factor a 5 anni: 1.448
Parole chiave: Heart, Dobutamine Echocardiography, Left Ventricular Dysfunction, Myocardial Scintigraphy, Myocardial Viability, Albumin Tc 99m, Cardiotonic Agent, Diagnostic Agent, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Radiopharmaceutical Agent, Acute Heart Infarction, Adult, Angiocardiography, Article, Clinical Article, Diagnostic Accuracy, Heart Function, Heart Left Ventricle Failure, Heart Muscle, Heart Muscle Revascularization, Human, Tomography, Clinical Trial, Computer Assisted Tomography, Echography, Female, Heart Left Ventricle Function, Middle Aged, Sensitivity And Specificity, Myocardial Infarction, Technetium Tc 99m Sestamibi, X-Ray Computed,
Introduction. We investigated the role of technetium-99m (99mTc) sestamibi cardiac imaging and dobutamine echocardiography in detecting myocardial viability early after acute myocardial infarction. Material and methods. Nineteen patients (mean age 52 ± 10 years) underwent coronary angiography, low-dose dobutamine echocardiography and rest 99mTc sestamibi imaging within 10 days of myocardial infarction. All patients were revascularized. Resting echocardiogram was repeated 8 months later to evaluate segmental functional recovery. Results. Sixty-one of 108 akinetic or dyskinetic segments at baseline showed functional recovery after revascularization. Sensitivity in predicting segmental functional recovery was 87% for sestamibi imaging and 66% for dobutamine echocardiography (p < 0.001), while specificity and accuracy were comparable. Sestamibi activity was the strongest predictor of segmental functional recovery (p < 0.001). Conclusions. Dobutamine echocardiography predicts functional recovery after myocardial infarction. However, sestamibi imaging is useful to identify patients with dysfunctional segments without contractile reserve which may benefit by revascularization.
Centro de la Med. Nucleare del CNR, Universita Federico II, Via Pansini 5, 80131 Napoli NA, Italy
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