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Segmentazione RM cerebrale basata sulla rilassometria
Responsabile: Marco Comerci, marco.comerciibb.cnr.it

Descrizione:
Sviluppo, messa a punto e sperimentazione di uno strumento software che calcola i rates (velocità) di rilassamento RM e densità protonica voxel per voxel (immagini QMCI), e segmenta la maggior parte dei tessuti del cervello, tra cui lesioni di sclerosi multipla.
La versione attuale, validata a 1 e 1. 5 Tesla, segmenta studi del cervello nei seguenti 18 compartimenti: Materia Grigia (GM); Sostanza bianca (WM); Demielinizzata / Bianca Anormale (AWM); Liquido Cerebrospinale (CSF); Globo Pallido; Putamen; Talamo; Nucleo Caudato; Sostanza Nigra; Nucleo Rosso; Nucleo Dentato; Muscolo, Grasso; Umor Vitreo; Tessuti Connettivi intra-cranici ed extra-cranici; Fluidi extra-cranici; e tessuti a bassa densità protonica. Il software produce informazioni volumetriche e rilassmetriche di ogni comparto.
Questa segmentazione basata su modello, utilizza velocità di rilassamento, densità protonica e informazioni anatomiche.
Il software è configurabile e può essere ottimizzato per varie situazioni ambientali, come diverse caratteristiche dello scanner e diverse regioni anatomiche (vedi anche Segmentazione RM arto basata sulla rilassometria).
Un modulo per la valutazione automatica di follow-up è stato inoltre sviluppato: allinea studi basali e di follow-up con coregistrazione rigida (basata sulla mutual information normalizzata del software SPM), taglia fuori i tessuti non comuni a tutti gli studi ed esegue l'analisi di Pearson su volumi e rates.
Applicazione per la ricerca neurologica: invecchiamento; Malattia di Alzheimer; Schizofrenia; malattie degenerative; correzione dell'effetto volume parziale per la PET e SPECT.
I miglioramenti attualmente in fase di test includono: segmentazione di studi cervello a 3T; correzione disomogeneità RM in ricezione e trasmissione (critico per studi 3T); Stima automatica del reale angolo di flip; registrazione di semi-serie disallineate. Registrazione affine di basale e dl follow-up per tener conto della deriva del gradiente MR; Miglioramento del modello anatomico e di segnale per gli studi del cervello.
I miglioramenti pianificati futuri sono: supporto fast spin Echo; supporto 3D FFE simil- T1w; Altre sequenze veloci 3D per le mappe rilassamento; Modello anatomico e di segnale ulteriormente migliorati per gli studi del cervello; segmentazione iterativa.

Aree di ricerca: Imaging Quantitativo

Attori:
Arturo Brunetti,
Mario Quarantelli, quaranteunina.it,
Anna Prinster, anna.prinsteribb.cnr.it,
Bruno Alfano,
Marco Comerci, marco.comerciibb.cnr.it,


Immagine QMCI e corrispondente immagine segmentata

Non disponibili.
A multiparametric and multiscale approach to automated segmentation of brain veins (accesso riservato) (118 views)
An MRI digital brain phantom for validation of segmentation methods (accesso riservato) (417 views)
An Ontology-Based Technique for Validation of MRI Brain Segmentation Methods (accesso riservato) (108 views)
Assessment of an automated vein segmentation algorithm for MRI brain acquisitions at different field strengths (dominio pubblico) (71 views)
Automated Segmentation and Measurement of Global White Matter Lesion Volume in Patients With Multiple Sclerosis (accesso riservato) (407 views)
Automated segmentation of multispectral brain MR images (accesso riservato) (88 views)
Automatic Segmentation of the Brain and Intracranial Cerebrospinal Fluid in T1-Weighted Volume MRI Scans of the Head, and Its Application to Serial Cerebral and Intracranial Volumetry (dominio pubblico) (90 views)
Fully automatic segmentation of white matter hyperintensities in MR images of the elderly (accesso riservato) (81 views)
Histogram-Based Characterization of Healthy and Ischemic Brain Tissues Using Multiparametric MR Imaging Including Apparent Diffusion Coefficient Maps and Relaxometry (dominio pubblico) (97 views)
Liver and Spleen Volumetry with Quantitative MR Imaging and Dual-Space Clustering Segmentation (dominio pubblico) (82 views)
Measurement of Global Brain Atrophy in Alzheimer’s Disease With Unsupervised Segmentation of Spin-Echo MRI Studies (accesso riservato) (136 views)
Multi-parametric algorithm for the automated segmentation of brain vein (dominio pubblico) (82 views)
Novel whole brain segmentation and volume estimation using quantitative MRI (accesso riservato) (105 views)
Probabilistic segmentation of brain tissue in MR imaging (accesso riservato) (82 views)
Probabilistic segmentation of white matter lesions in MR imaging (accesso riservato) (81 views)
Reproducibility of Intracranial Volume Measurement by Unsupervised Multispectral Brain Segmentation (accesso riservato) (385 views)
Segmentation of magnetic resonance brain images through discriminant analysis (accesso riservato) (105 views)
Semiautomatic Regional Segmentation to Measure Orbital Fat Volumes in Thyroid-Associated Ophthalmopathy A Validation Study (accesso riservato) (126 views)
Unified segmentation based correction of R1 brain maps for RF transmit field inhomogeneities (UNICORT) (accesso riservato) (95 views)
Unsupervised, Automated Segmentation of the Normal Brain Using a Multispectral Relaxometric Magnetic Resonance Approach (accesso riservato) (410 views)
White matter lesion extension to automatic brain tissue segmentation on MRI (accesso riservato) (99 views)
Whole-brain atrophy in multiple sclerosis measured by two segmentation processes from various MRI sequences (accesso riservato) (91 views)
[Cerca bibliografia correlata su PubMed]



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* . Early diagnosis of breast cancer by using Fast field cycling relaxometry (FFC-NMRD): investigations of ex-vivo murine breast tissue (6 visite)
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Pontillo G, Cocozza S, Lanzillo R, Borrelli P, De Rosa A, Brescia Morra V, Tedeschi E, Palma G
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* Assessment of an automated vein segmentation algorithm for MRI brain acquisitions at different field strengths (107 visite) (PDF 71 visite)
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6th Annual Meeting Of The International Society For Neurovascular Disease, 2016 Apr; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Multi-parametric algorithm for the automated segmentation of brain vein (109 visite) (PDF 82 visite)
Monti S, Borrelli P, Cocozza S, Salvatore M, Mancini M, Tedeschi E, Palma G
6th Annual Meeting Of The International Society For Neurovascular Disease, 2016 Apr; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* In vivo dentate nucleus MRI relaxometry correlates with previous administration of Gadolinium-based contrast agents (76 visite)
Tedeschi E, Palma G, Canna A, Cocozza S, Russo C, Borrelli P, Lanzillo R, Angelini V, Postiglione E, Morra VB, Salvatore M, Brunetti A, Quarantelli M
Eur Radiol (ISSN: 1432-1084electronic, 0938-7994linking), 2016 Feb 23; N/D: 1-8.
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* A multiparametric and multiscale approach to automated segmentation of brain veins (123 visite) (PDF 118 visite)
Monti S, Palma G, Borrelli P, Tedeschi E, Cocozza S, Salvatore M, Mancini M
Proceedings Of Engineering In Medicine And Biology Society, 2015; N/D: 3041-3044.
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* Does Gadolinium Change the Relaxometry of the Dentate Nuclei? A Quantitative Multi-parametric MRI Study (81 visite)
Tedeschi E, Russo C, Cocozza S, Palma G, Canna A, Borrelli P, Lanzillo R, Angelini V, Postiglione E, Brescia Morra V, Brunetti A, Salvatore M
Rsna 101st Scientific Assembly And Annual Meeting, 2015; N/D: N/D-N/D.
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* MULTIPARAMETRIC AUTOMATED SEGMENTATION OF BRAIN VEINS (147 visite)
Monti S, Palma G, Tedeschi E, Borrelli P, Cocozza S, Salvatore M, Mancini M
Veins And Lymphatics (ISSN: 2279-7483), 2015; 4(s1): 13-13.
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* Self-Trained Supervised Segmentation of Subcortical Brain Structures Using Multispectral Magnetic Resonance Images (147 visite)
Larobina M, Murino L, Cervo A, Alfano B
Biomed Research International, 2015; 2015: N/D-9.
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* Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study (166 visite) (PDF 126 visite)
Comerci M, Elefante A, Strianese D, Senese R, Bonavolonta P, Alfano B, Bonavolonta B, Brunetti A
Neuroradiol J (ISSN: 1971-4009, 1971-4009print, 1971-4009linking), 2013 Aug; 26(4): 373-379.
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* An MRI digital brain phantom for validation of segmentation methods (160 visite) (PDF 417 visite)
Alfano B, Comerci M, Larobina M, Prinster A, Hornak JP, Selvan SE, Amato U, Quarantelli M, Tedeschi G, Brunetti A, Salvatore M
Med Image Anal (ISSN: 1361-8415, 1361-8423, 1361-8415linking), 2011 Jun; 15(3): 329-339.
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* An ontology-based technique for validation of MRI brain segmentation methods (149 visite) (PDF 108 visite)
Alfano B, Comerci M, De Pietro G, Esposito A
Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2007; 4805LNCS(PART1): 566-575.
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* Automated brain MR segmentation in a large MS population (136 visite)
Tedeschi G, Dinacci D, Lavorgna L, Bonavita V, Livrea P, Quattrone A, Messina C, Savettieri G, Paciello M, Reggio A, Brunetti A, Russo P, Alfano B
Neurology (ISSN: 0028-3878, 1526-632x), 2004 Apr 13; 62(7): N/D-N/D.
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* Segmentation of magnetic resonance brain images through discriminant analysis (201 visite) (PDF 105 visite)
Amato U, Larobina M, Antoniadis A, Alfano B
J Neurosci Methods (ISSN: 0165-0270), 2003 Dec 30; 131(1-2): 65-74.
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Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis (167 visite) (PDF 407 visite)
Alfano B, Brunetti A, Larobina M, Quarantelli M, Tedeschi E, Ciarmiello A, Covelli EM, Salvatore M
Journal Of Magnetic Resonance Imaging (ISSN: 1053-1807), 2000 Dec; 12(6): 799-807.
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Measurement of global brain atrophy in Alzheimer's disease with unsupervised segmentation of spin-echo MRI studies (158 visite) (PDF 136 visite)
Brunetti A, Postiglione A, Tedeschi E, Ciarmiello A, Quarantelli M, Covelli EM, Milan G, Larobina M, Soricelli A, Sodano A, Alfano B
Journal Of Magnetic Resonance Imaging (ISSN: 1053-1807), 2000 Mar; 11(3): 260-266.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Measurement of global drain atrophy in Alzheimer's disease with unsupervised segmentation of spin-echo MRI studies (139 visite)
Brunetti A, Postiglione A, Tedeschi E, Ciarmiello A, Quarantelli M, Covelli E, Milan G, Larobina M, Soricelli A, Sodano A, Alfano B
Journal Of Magnetic Resonance Imaging (ISSN: 1053-1807), 2000 Mar; 11(3): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Validation of an automated regional brain segmentation method using a stereotactic Talairach approach (126 visite)
Larobina M, Quarantelli M, Tedeschi E, Brunetti A, Alfano B, Salvatore M
Surgeryinternational Congress Series Car 97 Computer Assisted Radiology And (ISSN: 0531-5131), 1999; 1191: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation (160 visite) (PDF 385 visite)
Alfano B, Quarantelli M, Brunetti A, Larobina M, Covelli EM, Tedeschi E, Salvatore M
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic), 1998 Mar; 39(3): 497-499.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric magnetic resonance approach (183 visite) (PDF 410 visite)
Alfano B, Brunetti A, Covelli EM, Quarantelli M, Panico M, Ciarmiello A, Salvatore M
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1997 Jan; 37(1): 84-93.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Fully-automated multispectral MR brain segmentation for detection and volumetric measurement of white matter lesions (129 visite)
Alfano B, Brunetti A, Quarantelli M, Larobina M, Covelli EM, Tedeschi E, Ciarmiello A, Salvatore M
Surgeryinternational Congress Series Car 97 Computer Assisted Radiology And (ISSN: 0531-5131), 1997; 1134: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Unsupervised multifeature MR segmentation for assessment of intracranial liquoral spaces: Comparison with conventional linear measures (129 visite)
Brunetti A, Covelli E, Tedeschi E, Quarantelli M, Soricelli A, Salvatore M, Alfano B
Surgeryinternational Congress Series Car 97 Computer Assisted Radiology And (ISSN: 0531-5131), 1996; 1124: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Automatic segmentation and evaluation of the volume of gray matter, white matter and cerebrospinal fluid by MRI (131 visite)
ALFANO B, ARPAIA M, BRUNETTI A, COVELLI E, CASTELLI L, CARACO C, SORICELLI A, TEDESCHI E, SALVATORE M
Neuroradiology 1994, 1994; N/D: N/D-N/D.
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23 Records (13 escludendo Abstract e Conferenze).
Impact factor totale: 39.631 (27.74 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 45.814 (27.412 escludendo Abstract e Conferenze).

Interrogazione bibliografica effettuata: ([btitle] "segmentation" OR [btitle] "relaxometry" OR [btitle] "followup" OR [btitle] "Relaxometry" OR [btitle] "segmentation")






Ultima modifica di Marco Comerci in data Wednesday 27 April 2016, 11:36:26
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