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Sviluppo di software per fantoccio digitale RM di cervello
Responsabile: Marco Comerci, marco.comerciibb.cnr.it

Descrizione:
Questa attività comprende lo sviluppo e la messa a punto di uno strumento software che può produrre fantocci digitali MR del cervello, che simulano le distribuzioni dei rates di rilassamento di veri studi di riferimento.
I fantocci digitali del cervello sono necessari per valutare le prestazioni dei metodi di segmentazione, fornendo un gold standard, contro il quale confrontare la segmentazione prodotta dai software.
Il fantoccio è composto da 17 compartimenti di tessuto e di un compartimento di materia bianca anomala opzionale, simulando le lesioni della SM.
Il software ha quattro modelli di testa, due volontari normali e due modelli SM. Attualmente il software permette di specificare manualmente le intensità medie dei segnali dei compartimenti, orientamento, posizione, rumore e altri parametri di segnale oppure derivarli da uno studio di riferimento, segmentato automaticamente dal software di segmentazione, opzionalmente deformando il fantoccio alla forma dello studio di riferimento.
Sono disponibili per il download quattro fantocci di esempio, uno per ogni modello, e fantocci a questo link.

Aree di ricerca: Imaging Quantitativo

Attori:
Marco Comerci, marco.comerciibb.cnr.it,
Bruno Alfano,
Anna Prinster, anna.prinsteribb.cnr.it,


Modello fisico: R1 e compartimenti

QMCI:Alfano BBrunetti A, Arpaia M, Ciarmiello A, Covelli EM, Salvatore M, J Magn Reson Imaging, 1995 Mar-Apr;5 (2):217-225Alfano BBrunetti A, Ciarmiello A, Salvatore M, J Comput Assist Tomogr, 1992 Jul-Aug;16 (4):634-640

Segmentation:
Alfano BBrunetti ALarobina MQuarantelli MTedeschi E, Ciarmiello A, Covelli EM, Salvatore M, J Magn Reson Imaging, 2000 Dec;12 (6):799-807Alfano BQuarantelli MBrunetti ALarobina M, Covelli EM, Tedeschi ESalvatore M, Magn Reson Med, 1998 Mar;39 (3):497-499Alfano BBrunetti A, Covelli EM, Quarantelli MPanico M, Ciarmiello A, Salvatore M, Magn Reson Med, 1997 Jan;37 (1):84-93

Phantom:
Alfano BComerci MLarobina MPrinster A, Hornak JP, Selvan SE, Amato U, Quarantelli M, Tedeschi G, Brunetti ASalvatore M, Med Image Anal, 2011 Jun;15 (3):329-339
A multiparametric and multiscale approach to automated segmentation of brain veins (accesso riservato) (104 views)
An MRI digital brain phantom for validation of segmentation methods (accesso riservato) (378 views)
An Ontology-Based Technique for Validation of MRI Brain Segmentation Methods (accesso riservato) (97 views)
Assessment of an automated vein segmentation algorithm for MRI brain acquisitions at different field strengths (dominio pubblico) (60 views)
Automated Segmentation and Measurement of Global White Matter Lesion Volume in Patients With Multiple Sclerosis (accesso riservato) (370 views)
Automated segmentation of multispectral brain MR images (accesso riservato) (77 views)
Automatic Segmentation of the Brain and Intracranial Cerebrospinal Fluid in T1-Weighted Volume MRI Scans of the Head, and Its Application to Serial Cerebral and Intracranial Volumetry (dominio pubblico) (80 views)
Fully automatic segmentation of white matter hyperintensities in MR images of the elderly (accesso riservato) (70 views)
Histogram-Based Characterization of Healthy and Ischemic Brain Tissues Using Multiparametric MR Imaging Including Apparent Diffusion Coefficient Maps and Relaxometry (dominio pubblico) (86 views)
Liver and Spleen Volumetry with Quantitative MR Imaging and Dual-Space Clustering Segmentation (dominio pubblico) (72 views)
Measurement of Global Brain Atrophy in Alzheimer’s Disease With Unsupervised Segmentation of Spin-Echo MRI Studies (accesso riservato) (124 views)
Multi-parametric algorithm for the automated segmentation of brain vein (dominio pubblico) (68 views)
Novel whole brain segmentation and volume estimation using quantitative MRI (accesso riservato) (92 views)
Probabilistic segmentation of brain tissue in MR imaging (accesso riservato) (70 views)
Probabilistic segmentation of white matter lesions in MR imaging (accesso riservato) (70 views)
Reproducibility of Intracranial Volume Measurement by Unsupervised Multispectral Brain Segmentation (accesso riservato) (347 views)
Segmentation of magnetic resonance brain images through discriminant analysis (accesso riservato) (91 views)
Semiautomatic Regional Segmentation to Measure Orbital Fat Volumes in Thyroid-Associated Ophthalmopathy A Validation Study (accesso riservato) (116 views)
Simultaneous Display of Multiple MR Parameters with "Quantitative Magnetic Color Imaging" (accesso riservato) (367 views)
Unified segmentation based correction of R1 brain maps for RF transmit field inhomogeneities (UNICORT) (accesso riservato) (84 views)
Unsupervised, Automated Segmentation of the Normal Brain Using a Multispectral Relaxometric Magnetic Resonance Approach (accesso riservato) (372 views)
White matter lesion extension to automatic brain tissue segmentation on MRI (accesso riservato) (88 views)
Whole-brain atrophy in multiple sclerosis measured by two segmentation processes from various MRI sequences (accesso riservato) (80 views)
[Cerca bibliografia correlata su PubMed]



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* Brain Susceptibility Changes in a Patient with Natalizumab-Related Progressive Multifocal Leukoencephalopathy: A Longitudinal Quantitative Susceptibility Mapping and Relaxometry Study (27 visite)
Pontillo G, Cocozza S, Lanzillo R, Borrelli P, De Rosa A, Brescia Morra V, Tedeschi E, Palma G
Front Neurol (ISSN: 1664-2295print, 1664-2295linking), 2017 Jun 19; 8: 294-294.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Assessment of an automated vein segmentation algorithm for MRI brain acquisitions at different field strengths (93 visite) (PDF 60 visite)
Monti S, Borrelli P, Cocozza S, Straub S, Ladd ME, Salvatore M, Mancini M, Tedeschi E, Palma G
6th Annual Meeting Of The International Society For Neurovascular Disease, 2016 Apr; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Multi-parametric algorithm for the automated segmentation of brain vein (94 visite) (PDF 68 visite)
Monti S, Borrelli P, Cocozza S, Salvatore M, Mancini M, Tedeschi E, Palma G
6th Annual Meeting Of The International Society For Neurovascular Disease, 2016 Apr; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* In vivo dentate nucleus MRI relaxometry correlates with previous administration of Gadolinium-based contrast agents (61 visite)
Tedeschi E, Palma G, Canna A, Cocozza S, Russo C, Borrelli P, Lanzillo R, Angelini V, Postiglione E, Morra VB, Salvatore M, Brunetti A, Quarantelli M
Eur Radiol (ISSN: 1432-1084electronic, 0938-7994linking), 2016 Feb 23; N/D: 1-8.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Software for computerised analysis of cardiotocographic traces (389 visite) (PDF 107 visite)
Romano M, Bifulco P, Ruffo M, Improta G, Clemente F, Cesarelli M
Comput Methods Programs Biomed (ISSN: 1872-7565electronic, 0169-2607linking), 2016 Feb; 124: 121-137.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A Novel Multiparametric Approach to 3D Quantitative MRI of the Brain (230 visite) (PDF 124 visite)
Palma G, Tedeschi E, Borrelli P, Cocozza S, Russo C, Liu S, Ye Y, Comerci M, Alfano B, Salvatore M, Haacke EM, Mancini M
Plos One (ISSN: 1932-6203electronic, 1932-6203linking), 2015 Aug 18; 10(8): e0134963-e0134963.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A multiparametric and multiscale approach to automated segmentation of brain veins (105 visite) (PDF 104 visite)
Monti S, Palma G, Borrelli P, Tedeschi E, Cocozza S, Salvatore M, Mancini M
Proceedings Of Engineering In Medicine And Biology Society, 2015; N/D: 3041-3044.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Does Gadolinium Change the Relaxometry of the Dentate Nuclei? A Quantitative Multi-parametric MRI Study (66 visite)
Tedeschi E, Russo C, Cocozza S, Palma G, Canna A, Borrelli P, Lanzillo R, Angelini V, Postiglione E, Brescia Morra V, Brunetti A, Salvatore M
Rsna 101st Scientific Assembly And Annual Meeting, 2015; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Mapping the brain by a new multiparametric quantitative MRI method (110 visite)
Palma G, Tedeschi E, Borrelli P, Cocozza S, Russo C, Canna A, Comerci M, Alfano B, Mancini M
Rsna 101st Scientific Assembly And Annual Meeting, 2015; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* MULTIPARAMETRIC AUTOMATED SEGMENTATION OF BRAIN VEINS (129 visite)
Monti S, Palma G, Tedeschi E, Borrelli P, Cocozza S, Salvatore M, Mancini M
Veins And Lymphatics (ISSN: 2279-7483), 2015; 4(s1): 13-13.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Self-Trained Supervised Segmentation of Subcortical Brain Structures Using Multispectral Magnetic Resonance Images (134 visite)
Larobina M, Murino L, Cervo A, Alfano B
Biomed Research International, 2015; 2015: N/D-9.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study (153 visite) (PDF 116 visite)
Comerci M, Elefante A, Strianese D, Senese R, Bonavolonta P, Alfano B, Bonavolonta B, Brunetti A
Neuroradiol J (ISSN: 1971-4009, 1971-4009print, 1971-4009linking), 2013 Aug; 26(4): 373-379.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* An MRI digital brain phantom for validation of segmentation methods (144 visite) (PDF 378 visite)
Alfano B, Comerci M, Larobina M, Prinster A, Hornak JP, Selvan SE, Amato U, Quarantelli M, Tedeschi G, Brunetti A, Salvatore M
Med Image Anal (ISSN: 1361-8415, 1361-8423, 1361-8415linking), 2011 Jun; 15(3): 329-339.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Assessment of left ventricular volumes with cardiac MRI: Comparison between two semiautomated quantitative software packages (55 visite)
Messalli G, Palumbo A, Maffei E, Martini C, Seitun S, Aldrovandi A, Imbriaco M, Salvatore M, Weustink A, Mollet N, Cademartiri F
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2009 Sep; 114(5): 718-727.
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* Quantitative myocardial-perfusion SPECT: Comparison of three state-of-the-art software packages (65 visite)
Wolak A, Slomka PJ, Fish MB, Lorenzo S, Acampa W, Berman DS, Germano G
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 27-34.
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* An ontology-based technique for validation of MRI brain segmentation methods (135 visite) (PDF 97 visite)
Alfano B, Comerci M, De Pietro G, Esposito A
Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2007; 4805LNCS(PART1): 566-575.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Automated brain MR segmentation in a large MS population (127 visite)
Tedeschi G, Dinacci D, Lavorgna L, Bonavita V, Livrea P, Quattrone A, Messina C, Savettieri G, Paciello M, Reggio A, Brunetti A, Russo P, Alfano B
Neurology (ISSN: 0028-3878, 1526-632x), 2004 Apr 13; 62(7): N/D-N/D.
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* Integrated software for the analysis of brain PET/SPECT studies with partial-volume-effect correction (128 visite) (PDF 96 visite)
Quarantelli M, Berkouk K, Prinster A, Landeau B, Svarer C, Balkay L, Alfano B, Brunetti A, Baron JC, Salvatore M
Journal Of Nuclear Medicine (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2004 Feb; 45(2): 192-201.
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* Pvelab: Software For Correction Of Functional Images For Partial Volume Errors (120 visite)
Rask T, Dyrby T, Comerci M, Quarantelli M, Alfano B, Berkouk K, Baron J, Colchester A, Hojjat A, Knudsen GM, Paulson OB, Svarer C
Proceedings Of The 10th Meeting Of The Organisation For Human Brain Mapping, 2004; Abstract: N/D-N/D.
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* Segmentation of magnetic resonance brain images through discriminant analysis (185 visite) (PDF 91 visite)
Amato U, Larobina M, Antoniadis A, Alfano B
J Neurosci Methods (ISSN: 0165-0270), 2003 Dec 30; 131(1-2): 65-74.
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Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis (153 visite) (PDF 370 visite)
Alfano B, Brunetti A, Larobina M, Quarantelli M, Tedeschi E, Ciarmiello A, Covelli EM, Salvatore M
Journal Of Magnetic Resonance Imaging (ISSN: 1053-1807), 2000 Dec; 12(6): 799-807.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Measurement of global brain atrophy in Alzheimer's disease with unsupervised segmentation of spin-echo MRI studies (138 visite) (PDF 124 visite)
Brunetti A, Postiglione A, Tedeschi E, Ciarmiello A, Quarantelli M, Covelli EM, Milan G, Larobina M, Soricelli A, Sodano A, Alfano B
Journal Of Magnetic Resonance Imaging (ISSN: 1053-1807), 2000 Mar; 11(3): 260-266.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Measurement of global drain atrophy in Alzheimer's disease with unsupervised segmentation of spin-echo MRI studies (121 visite)
Brunetti A, Postiglione A, Tedeschi E, Ciarmiello A, Quarantelli M, Covelli E, Milan G, Larobina M, Soricelli A, Sodano A, Alfano B
Journal Of Magnetic Resonance Imaging (ISSN: 1053-1807), 2000 Mar; 11(3): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Validation of an automated regional brain segmentation method using a stereotactic Talairach approach (115 visite)
Larobina M, Quarantelli M, Tedeschi E, Brunetti A, Alfano B, Salvatore M
Surgeryinternational Congress Series Car 97 Computer Assisted Radiology And (ISSN: 0531-5131), 1999; 1191: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation (144 visite) (PDF 347 visite)
Alfano B, Quarantelli M, Brunetti A, Larobina M, Covelli EM, Tedeschi E, Salvatore M
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic), 1998 Mar; 39(3): 497-499.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric magnetic resonance approach (165 visite) (PDF 372 visite)
Alfano B, Brunetti A, Covelli EM, Quarantelli M, Panico M, Ciarmiello A, Salvatore M
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1997 Jan; 37(1): 84-93.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Fully-automated multispectral MR brain segmentation for detection and volumetric measurement of white matter lesions (114 visite)
Alfano B, Brunetti A, Quarantelli M, Larobina M, Covelli EM, Tedeschi E, Ciarmiello A, Salvatore M
Surgeryinternational Congress Series Car 97 Computer Assisted Radiology And (ISSN: 0531-5131), 1997; 1134: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Unsupervised multifeature MR segmentation for assessment of intracranial liquoral spaces: Comparison with conventional linear measures (117 visite)
Brunetti A, Covelli E, Tedeschi E, Quarantelli M, Soricelli A, Salvatore M, Alfano B
Surgeryinternational Congress Series Car 97 Computer Assisted Radiology And (ISSN: 0531-5131), 1996; 1124: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Multiparametric display of spin-echo data from MR studies of brain (67 visite) (PDF 366 visite)
Alfano B, Brunetti A, Arpaia M, Ciarmiello A, Covelli EM, Salvatore M
Journal Of Magnetic Resonance Imaging (ISSN: 1053-1807), 1995 Mar; 5(2): 217-225.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Automatic segmentation and evaluation of the volume of gray matter, white matter and cerebrospinal fluid by MRI (118 visite)
ALFANO B, ARPAIA M, BRUNETTI A, COVELLI E, CASTELLI L, CARACO C, SORICELLI A, TEDESCHI E, SALVATORE M
Neuroradiology 1994, 1994; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Multiparametric and dynamic MR imaging of sellar disease - Preliminary results (62 visite)
BRUNETTI A, COVELLI E, CASTELLI L, CARACO C, ARPAIA M, ALFANO B, TEDESCHI E, SALVATORE M
Neuroradiology 1994, 1994; N/D: N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Multiparametric characterization of lesions of the white matter in multiple sclerosis patients (47 visite)
BRUNETTI A, TEDESCHI G, ALFANO B, DICOSTANZO A, ALOJ L, ARPAIA M, COVELLI E, BONAVITA S, SALVATORE M
Neuroradiology 1994, 1994; N/D: N/D-N/D.
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Simultaneous display of multiple MR parameters with 'quantitative magnetic color imaging' (64 visite) (PDF 367 visite)
Alfano B, Brunetti A, Ciarmiello A, Salvatore M
J Comput Assisted Tomogr (ISSN: 0363-8715), 1992 Jul; 16(4): 634-640.
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QUANTITATIVE MAGNETIC COLOR IMAGING - NEW TECHNIQUE FOR SIMULTANEOUS REPRESENTATION OF MR PARAMETERS (49 visite)
ALFANO B, BRUNETTI A, CIARMIELLO A, SIMONETTI L, SALVATORE M
Neuroradiologia 1992 Vol Ii, 1992; N/D: N/D-N/D.
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QUANTITATIVE MAGNETIC COLOR IMAGING - PRELIMINARY EXPERIENCES WITH CLINICAL-APPLICATION (49 visite)
SIMONETTI L, ALFANO B, BRUNETTI A, LATESSA G, CIRILLO S, DELEHAYE L, GIUGLIANO V, CARANCI F, SMALTINO F, SALVATORE M, ELEFANTE R
Neuroradiologia 1992 Vol I, 1992; N/D: N/D-N/D.
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Hardware/software simulator of a silicon detector for digital radiography (51 visite)
Alfano B, Bencivelli W, Bertolucci E, Bottigli U, Bucciolini M, Conti M, Del Guerra A, Messineo A, Milano F, Randaccio P, Renzi R, Rosso V, Russo P, Stefanini A.
Physica Medica (ISSN: 1120-1797), 1990; 6(3-4): 239-241.
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36 Records (21 escludendo Abstract e Conferenze).
Impact factor totale: 55.419 (43.528 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 66.217 (47.815 escludendo Abstract e Conferenze).

Interrogazione bibliografica effettuata: ([btitle] "segmentation" OR [btitle] "relaxometry" OR [btitle] "quantitative magnetic color imaging" OR [btitle] "multiparametric" OR [btitle] "Software")






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