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Sviluppo di software per fantoccio digitale RM di cervello
Responsabile: Marco Comerci, marco.comerciibb.cnr.it

Descrizione:
Questa attività comprende lo sviluppo e la messa a punto di uno strumento software che può produrre fantocci digitali MR del cervello, che simulano le distribuzioni dei rates di rilassamento di veri studi di riferimento.
I fantocci digitali del cervello sono necessari per valutare le prestazioni dei metodi di segmentazione, fornendo un gold standard, contro il quale confrontare la segmentazione prodotta dai software.
Il fantoccio è composto da 17 compartimenti di tessuto e di un compartimento di materia bianca anomala opzionale, simulando le lesioni della SM.
Il software ha quattro modelli di testa, due volontari normali e due modelli SM. Attualmente il software permette di specificare manualmente le intensità medie dei segnali dei compartimenti, orientamento, posizione, rumore e altri parametri di segnale oppure derivarli da uno studio di riferimento, segmentato automaticamente dal software di segmentazione, opzionalmente deformando il fantoccio alla forma dello studio di riferimento.
Sono disponibili per il download quattro fantocci di esempio, uno per ogni modello, e fantocci a questo link.

Aree di ricerca: Imaging Quantitativo, 

Attori:
Marco Comerci, marco.comerciibb.cnr.it,
Bruno Alfano,
Anna Prinster, anna.prinsteribb.cnr.it,

Parole chiave: Mri, segmentation, relaxometry, phantom, quantitative magnetic color imaging, multiparametric

Modello fisico: R1 e compartimenti

QMCI:Alfano B, Brunetti A, Arpaia M, Ciarmiello A, Covelli EM, Salvatore M, J Magn Reson Imaging, 1995 Mar-Apr;5 (2):217-225Alfano B, Brunetti A, Ciarmiello A, Salvatore M, J Comput Assist Tomogr, 1992 Jul-Aug;16 (4):634-640

Segmentation:
Alfano B, Brunetti A, Larobina M, Quarantelli M, Tedeschi E, Ciarmiello A, Covelli EM, Salvatore M, J Magn Reson Imaging, 2000 Dec;12 (6):799-807Alfano B, Quarantelli M, Brunetti A, Larobina M, Covelli EM, Tedeschi E, Salvatore M, Magn Reson Med, 1998 Mar;39 (3):497-499Alfano B, Brunetti A, Covelli EM, Quarantelli M, Panico M, Ciarmiello A, Salvatore M, Magn Reson Med, 1997 Jan;37 (1):84-93

Phantom:
Alfano B, Comerci M, Larobina M, Prinster A, Hornak JP, Selvan SE, Amato U, Quarantelli M, Tedeschi G, Brunetti A, Salvatore M, Med Image Anal, 2011 Jun;15 (3):329-339
A multiparametric and multiscale approach to automated segmentation of brain veins (accesso riservato) (104 views)
An MRI digital brain phantom for validation of segmentation methods (accesso riservato) (378 views)
An Ontology-Based Technique for Validation of MRI Brain Segmentation Methods (accesso riservato) (97 views)
Assessment of an automated vein segmentation algorithm for MRI brain acquisitions at different field strengths (dominio pubblico) (60 views)
Automated Segmentation and Measurement of Global White Matter Lesion Volume in Patients With Multiple Sclerosis (accesso riservato) (370 views)
Automated segmentation of multispectral brain MR images (accesso riservato) (77 views)
Automatic Segmentation of the Brain and Intracranial Cerebrospinal Fluid in T1-Weighted Volume MRI Scans of the Head, and Its Application to Serial Cerebral and Intracranial Volumetry (dominio pubblico) (80 views)
Fully automatic segmentation of white matter hyperintensities in MR images of the elderly (accesso riservato) (70 views)
Histogram-Based Characterization of Healthy and Ischemic Brain Tissues Using Multiparametric MR Imaging Including Apparent Diffusion Coefficient Maps and Relaxometry (dominio pubblico) (86 views)
Liver and Spleen Volumetry with Quantitative MR Imaging and Dual-Space Clustering Segmentation (dominio pubblico) (72 views)
Measurement of Global Brain Atrophy in Alzheimer’s Disease With Unsupervised Segmentation of Spin-Echo MRI Studies (accesso riservato) (124 views)
Multi-parametric algorithm for the automated segmentation of brain vein (dominio pubblico) (68 views)
Novel whole brain segmentation and volume estimation using quantitative MRI (accesso riservato) (92 views)
Probabilistic segmentation of brain tissue in MR imaging (accesso riservato) (70 views)
Probabilistic segmentation of white matter lesions in MR imaging (accesso riservato) (70 views)
Reproducibility of Intracranial Volume Measurement by Unsupervised Multispectral Brain Segmentation (accesso riservato) (347 views)
Segmentation of magnetic resonance brain images through discriminant analysis (accesso riservato) (91 views)
Semiautomatic Regional Segmentation to Measure Orbital Fat Volumes in Thyroid-Associated Ophthalmopathy A Validation Study (accesso riservato) (116 views)
Simultaneous Display of Multiple MR Parameters with "Quantitative Magnetic Color Imaging" (accesso riservato) (367 views)
Unified segmentation based correction of R1 brain maps for RF transmit field inhomogeneities (UNICORT) (accesso riservato) (84 views)
Unsupervised, Automated Segmentation of the Normal Brain Using a Multispectral Relaxometric Magnetic Resonance Approach (accesso riservato) (372 views)
White matter lesion extension to automatic brain tissue segmentation on MRI (accesso riservato) (88 views)
Whole-brain atrophy in multiple sclerosis measured by two segmentation processes from various MRI sequences (accesso riservato) (80 views)
[Cerca bibliografia correlata su PubMed]


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Physica Medica (ISSN: 1120-1797), 1990; 6(3-4): 239-241.
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36 Records (21 escludendo Abstract e Conferenze).
Impact factor totale: 55.419 (43.528 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 66.217 (47.815 escludendo Abstract e Conferenze).

Interrogazione bibliografica effettuata: ([btitle] "segmentation" OR [btitle] "relaxometry" OR [btitle] "quantitative magnetic color imaging" OR [btitle] "multiparametric" OR [btitle] "Software")






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