Figure 1. Model of polyglutamine fibers as derived from molecular dynamics studies.
Figure 2. A 310 helical model of NT4 N-terminal peptide derived from the simulation (cyan) superimposed on the N-terminal region of the NT4 (pink) in the NT4-TrkB complex.
|▼ Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Nucleic acid and protein binding studies|
|▼ New peptide–based molecules as NGF mimetics in the therapy of neurological dysfunctions Nuove molecole di natura peptidica che mimano l’NGF per la terapia di malattie neurologiche|