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Collegamenti

LightDyNAmics

DNA as a training platform for photodynamics processes in soft materials

LightDyNAmics is a multidisciplinary European Training Network funded by the European Commission under the Horizon Marie Sklodowska-Curie Action



 

project

Light-soft matter interaction is at the heart of many fields in science and technology. To fully understand photoactivated processes in multi-chromophore soft materials, a substantial innovation of existing methodologies is needed. LightDyNAmics uses DNA photoactivated dynamics as a training platform for developing new methods and training researchers. The interactions between UV light and DNA has a fundamental biological relevance as it can damage the genetic code. As DNA is the archetype of soft materials used in biomedical and optoelectronic applications, it allows us to use it as a challenging playground for exploring the main processes triggered by light in complex soft materials.

network

The LightDyNAmics network consists of 21 partners from 9 European Countries.

objectives

The main goal of LightDyNAmics is to achieve a complete understanding of the ultrafast dynamical processes at the molecular scale induced by UV light absorption and DNA, and to einveil the mechanisms leading to photodamage of the genetic code. The project will transfer this knowledge to a broad class of optoelectronic materials, highly relevant for Europe's high-tec industries. At the same time, LightDyNAmics will train 15 Early Stage Resarchers by crossing the border between theoretical and experimental expertise by performing independent, yet interrelated and complementary research projects focussed on three scientific objectives:

  • to develop and optimize a variety of complementary experimental and computational methods for the investigation of ultrafast dynamics in multi-chromophore systems;
  • to apply these methods to elucidate photoinduced processes in DNA tracts of different size and complexity, from simple nucleobases in the gas phase to genomic DNA, over different timescales from light absorption all the way to the formation of lesions;
  • to generalize the acquired knowledge and transfer it to other multi-chromophore, soft materials of fundamental and technological interest, identifying the photoinduced processes, their spectral signatures, their yields and dynamics.

 

 

Available position

IBB Project

CNR, Institute of Biostructure and Bioimaging offers 1 PhD position (Early Stage Researcher) within the LightDyNAMics ETN project (grant agreement n. 765266) funded by HORIZON 2020/Marie Sklodowska Curie Action for the implementation of the following research project:

“Exciton and charge separation: computational models”

Synopsis

The main aims of the research project are:
1. Develop effective mixed quantum/classical computational strategies for the simulation of electronic spectra and the dynamics of excitation energy (EET) and charge transfers (CT) in strongly coupled multichromophore systems.
2. Applying these methods to investigate the excited state dynamics of polynucleotides, with special reference to G-quadruplexes.

The candidate will work under the supervision of Dr. Roberto Improta and with the co-supervision of Dr. F. Santoro (ICCOM-CNR, Pisa) and of Dr. D. Markovitsi (LIDYL/CNRS, Paris), and the research activity will be performed in collaboration with their laboratories.

The candidate will be enrolled in the doctoral School in Biomolecular Science at the University of Campania ‘Luigi Vanvitelli”.
The salary is predicted to be ca 2700 euros per month after taxes.

For any further information please contact Roberto Improta: e-mail: robimp@unina.it

ICCOM Project

CNR, Institute of Chemistry of Organometallic Compunds offers 1 PhD position (Early Stage Researcher) within the LightDyNAMics ETN project (grant agreement n. 765266) funded by HORIZON 2020/Marie Sklodowska Curie Action for the implementation of the following research project:

“Quantum dynamics in nucleobases and small oligomers:
toward the simulation of time resolved spectra”


Synopsis

The main aims of the research project are:
1. Develop new effective computational strategies to compute pump-probe spectra and 2D electronic spectra from quantum dynamics (QD), to be directly compared with experiments.
2. Apply these methodologies to nucleobases and small oligomers addressing in detail the relation between the lifetimes obtained from fitting of spectroscopic traces and the underlying QD processes in the molecule.

The candidate will work under the supervision of Dr. Fabrizio Santoro and with the co-supervision of Dr. R. Improta (IBB-CNR, Napoli) and of Prof. G. Cerullo (POLIMI, Milano), and the research activity will be performed in collaboration with their laboratories.

The candidate will be enrolled in the doctoral School in Chemical and Materials Science at the University of Pisa.
The salary is predicted to be ca 2700 euros per month after taxes.

For any further information please contact Fabrizio Santoro: e-mail: fabrizio.santoro@iccom.cnr.it
1. Eligibility criteria
(a) Nationality: The candidate can be of any nationality.
(b) Mobility: By the closing date of the call for applicants, the candidate must not have resided or carried out his/her main activity in Italy for more than 12 months in the 3 years immediately prior to his/her recruitment under the project. Compulsory national service and/or short stays such as holidays are not taken into account.
(c) Qualifications: By the closing date of the call for applicants, the candidate shall have a master degree or equivalent in Chemistry, Physics, Material Sciences (or related topics) corresponding to the second level of studies.
(d) Foreign language: The candidate shall be fluent in written and spoken English.
(e) Experience: Preference will be given to candidates with a strong background and interest in one of the fields reported in (c). The ideal candidate will have a background in the theoretical study of photoinduced processes. Alternatively previous experience in Theoretical and Computational Chemistry  is welcome. Programming skills (Fortran, etc) are welcome too.
(f) Moreover, by the closing date of the call for applicants
− candidates shall not have been awarded a doctorate degree;
− The candidate should be in the first 4 years (full-time equivalent) of his/her research career. This includes the period of research training, starting from the date of obtaining the degree, which would formally entitle him/her to embark on a doctorate either in the country in which the degree was obtained or in Italy, irrespective of whether or not a doctorate is envisaged.

2. Information related to the supervision and the contract

- The employment contract offered is a full time, temporary contract with full social security coverage;
- The duration of the contract is 12 Months renewable up to 36 months;
- The monthly gross salary is 3,167.00 €. In case the successful applicant has family charges, an additional allowance will be allocated once not before Month 12 of the contract period.

3. Evaluation criteria and selection procedure

The evaluation will consist of two selection steps: the first based on the documentation provided by the candidates and the second based on the interview. Within each step, the marks given for each criterion by the reviewers will be used against an established pass/fail threshold.

Deadline for application is 11 June 2018.

The application procedure will be done by electronic submission through this website, by using the following link.
Please note that it is possible to apply to both positions, filling a different form for each position.


You should receive an automatic confirmation message from the website and a second letter from marianna.malgieri@ibb.cnr.it (for IBB position) and from "segreteria-pi@pi.iccom.cnr.it (for ICCOM position) when the applications have been regularly registered by the Institutes' administration. In the case you do not receive any of these two messages in few days after the submission, please contact "direttore@ibb.cnr.it , c.c. marianna.malgieri@ibb.cnr.it" for IBB position and segreteria-pi@pi.iccom.cnr.it for ICCOM position
The following information and documents will be required in the application:

- Europass CV, including a detailed description of the Full Time Equivalent (FTE) research experience;
- Proof of nationality (copy of passport or identity card);
- Copy in English or Italian of University diploma;
- Copy in English or Italian of study results (i.e. grades of university exams);
- Proof of language test results (e.g., British Council, TOEFL and IELTS) except for applicants whose mother tongue is English;
- Preferred research topics;
- Copy of publication(s);
- Motivation letter;
- Two reference letters.

The interview of candidates passing the first step of the evaluation procedure will be carried out via Skype in June 2018.



 


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Ultimo aggiornamento: Wednesday 12 December 2018, 13:45:33