|Area||Ricerca e Sviluppo|
|Indirizzo||Via De Amicis 95, 80145 Napoli - Italia|
|Telefono ufficio||+39 081 2203427|
|▼ Malattie Neoplastiche|
▼ Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions
▼ Characterization of the KCTD protein family: key factors in several biological processes
▼ Characterization of neurotoxic and neuroprotective factors by using computational methodologies
▼ Targeted Drug Delivery by integrin avb3 antagonist
▼ Protein aggregation and cytotoxicity: molecular, in vitro and in vivo biological studies
▼ Bioactive peptide-membrane assemblies
▼ Metals and small molecules in the regulation of the Ubiquitin Proteasome Pathway
▼ Peptide modulators of the VEGF-dependent angiogenesis
▼ CA IX as target for the development of new anti-tumour drugs
▼ Carbonic Anhydrase family as target for rational drug design
▼ Clinical Oncology
▼ Translational Molecular Imaging in Cancer
▼ Molecular imaging for personalized therapy in oncology
▼ Modeling radiation induced normal tissue effects
▼ Test e validazione di nuove sonde molecolari mediante imaging preclinico.
▼ Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Nucleic acid and protein binding studies
|▼ Imaging Quantitativo|
▼ Segmentazione RM cerebrale basata sulla rilassometria
▼ Manutenzione software di correzione per l'effetto di volume parziale
▼ Sviluppo di software per fantoccio digitale RM di cervello
▼ Sviluppo di un innovativo algoritmo di correzione di effetto di volume parziale
▼ Sviluppo di software General Purpose su GPU
|▼ Modeling radiation induced normal tissue effects|
|▼ Segmentazione cerebrale per applicazioni in radiologia oncologica|
CELLA Laura was born in Naples on 24th of July 1972.
Educations and academic degrees
2017: Award of the National Scientific Qualification (art.16 of the law 30 December 2010, n.240) from
the Italian Ministry of Education, Universities and Research (MIUR) as
Full Professor in Italian Universities (Applied Physics- D.D. 1532/2016)
2013: Award of the National Scientific Qualification (art.16 of the law 30 December 2010, n.240) from the Italian Ministry of Education, Universities and Research (MIUR) as Associate Professor in Italian Universities (Applied Physics)
2003: Specialist in medical physics. Three-years Post-graduate Program in Medical Physics, University of Rome "La Sapienza" Topic: Biodosimetry in breast cancer patients.
1997: Laurea Degree in Physics (cum laude) - University of Naples "Federico II" Thesis: The effect of track structure on the induction of chromosomal aberrations in murine cells.
The research activities focus on:
- imaging, planning, delivery and verification of external beam radiotherapy, including intensity-modulated, and particle beam radiotherapy
- quantitative analyses and modeling radiation induced normal tissue effects
- development of novel radiation detectors
2001 – current: Research Scientist Institute for Biostructure and Bioimages (IBB), National Council of Research (CNR), Italy
2003 – current: Consultant Medical Physicist at the University Hospital of Naples, Italy
2000-2001: Research Fellow at Physics Department , University of Naples "Federico II". Subject: Biodosimetry and radiotherapy optimization in breast and lung cancer
1999 - 2000: Research Fellow at Department of Radiation Medicine, Paul Scherrer Institut, Villigen, Zurich. (CH). Subject: Proton dosimetry and radiotherapy
1998 - 1999: Research Fellow at Division de Radio-Oncologie, Hopital Universitaire de Geneve (CH). Subject: Photon dosimetry and radiotherapy
Teaching courses and supervision
2013-2016 Adjunct Professor, School of Medical Physics University of Naples
2009-2011 Adjunct Professor, Degree Course for Radiologic Technologists
Supervisor for 3 completed M.Sc in Physics at University of Naples Federico II
Supervisor for 1 PhD student for the International PhD program on Novel Technologies for Materials, Sensors and Imaging at University of Naples Federico II
Grants and clinical trials
2017-2019 INFN project CSN V: Modeling and Verification for Ion beam Treatment planning (MoVeIT). WP2 leader.
2014 “Short-term mobility” grant from Italian National Research Council. Visiting scientist at Department of Medical Physics Memorial Sloan-Kettering Cancer Center (New York, USA). Research program: Complication probabilities models for radiation-induced lung and heart toxicities in Hodgkin’s lymphoma survivors. Application of statistical learning methods.
2012-2016 Project FIRB from Italian Ministry for Education and Research (MIUR) RBFR10Q0PT “DROPS” (Principal Investigator) (2012-2016).
2012-2016 POR Campania 2012 (n. 124 del 24 luglio 2013). Decorrenza 06/ 2013
2011 Project FIRB from Italian Ministry for Education and Research (MIUR) RBNE08YFN3 “MERIT” (2011)
2006-2012 Equal Estro EGF 102988 Phase III Head and Neck Clinical Trial conducted by GlaxoSmithKline (ClinicalTrials.gov Identifier NCT00424255, Site number: 32110).
2002-2016 Project FIRB from Italian Ministry for Education and Research (MIUR) RBNE015AKZ
Scientific journal involvements
Reviewer for several international radiotherapy and medical physics journals including Radiotherapy and Oncology, International Journal of Radiation Oncology, Biology and Physics, Radiation Oncology , Acta Oncologica, The British Journal of Radiology, Physica Medica, PlosOne, Zeitschrift für Medizinische Physik.
Professional membership & associations:
ESTRO member, ASTRO member, ILROG Council Member