* Exploring the ability of cyclic peptides to target SAM domains: a computational and experimental study (21 visite)
Mercurio FA, Di Natale C, Pirone L, Vincenzi M, Marasco D, De Luca S, Pedone EM, Leone M
Chembiochem (ISSN: 1439-4227linking), 2019 Sep 20; N/D: N/D-N/D.
Impact Factor: 2.641
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* Design and analysis of EphA2-SAM peptide ligands: A multi-disciplinary screening approach (53 visite)
Mercurio FA, Di Natale C, Pirone L, Marasco D, Calce E, Vincenzi M, Pedone EM, De Luca S, Leone M
Bioorg Chem (ISSN: 0045-2068linking), 2019 Mar; 84: 434-443.
Impact Factor: 3.929
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* The Growth Differentiation Factor 11 is Involved in Skin Fibroblast Ageing and is Induced by a Preparation of Peptides and Sugars Derived from Plant Cell Cultures (65 visite)
Tito A, Barbulova A, Zappelli C, Leone M, Ruvo M, Mercurio FA, Chambery A, Russo R, Colucci MG, Apone F
Mol Biotechnol (ISSN: 1073-6085linking, 1559-0305electronic), 2019 Mar; 61 (3 ): 209-220.
Impact Factor: 2.275
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* Sam domains in multiple diseases (38 visite)
Vincenzi M, Mercurio FA, Leone M
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2018 Oct 9; N/D: N/D-N/D.
Impact Factor: 3.469
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* Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2 (95 visite)
Mercurio FA, Pirone L, Di Natale C, Marasco D, Pedone EM, Leone M
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2018 Oct; 80: 602-610.
Impact Factor: 3.9
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* The antimicrobial peptides casocidins I and II: Solution structural studies in water and different membrane-mimetic environments (81 visite)
Mercurio FA, Scaloni A, Caira S, Leone M
Peptides (ISSN: 0196-9781linking, 1873-5169electronic), 2018 Sep 19; N/D: N/D-N/D.
Impact Factor: 2.851
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* Biochemical, biophysical and molecular dynamics studies on the proteoglycan-like domain of carbonic anhydrase IX (164 visite)
Langella E, Buonanno M, Vullo D, Dathan N, Leone M, Supuran C, De Simone G, Monti SM
Cell Mol Life Sci, 2018 Sep; 75: 3283-3296.
Impact Factor: 6.721
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* Self-Assembling of Fmoc-GC Peptide Nucleic Acid Dimers into Highly Fluorescent Aggregates (136 visite)
Avitabile C, Diaferia C, Della Ventura B, Mercurio FA, Leone M, Roviello V, Saviano M, Velotta R, Morelli G, Accardo A, Romanelli A
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Mar 26; 24(18): 4729-4735.
Impact Factor: 5.476
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* Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein (109 visite)
Buonanno M, Coppola M, Di Lelio I, Molisso D, Leone M, Pennacchio F, Langella E, Rao R, Monti SM
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Mar; 27(3): 620-632.
Impact Factor: 2.937
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* The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors (108 visite)
Mercurio FA, Di Natale C, Pirone L, Iannitti R, Marasco D, Pedone EM, Palumbo R, Leone M
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Dec 12; 7(1): 17474-17474.
Impact Factor: 4.122
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* Structure-activity studies of peptidomimetics based on kinase-inhibitory region of suppressors of cytokine signaling (137 visite)
La Manna S, Lopez-sanz L, Leone M, Brandi P, Scognamiglio PL, Morelli G, Novellino E, Gomez-guerrero C, Marasco D
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2017 Nov 20; N/D: N/D-N/D.
Impact Factor: 1.99
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* Structural investigation of a C-terminal EphA2 receptor mutant: Does mutation affect the structure and interaction properties of the Sam domain? (100 visite)
Mercurio FA, Costantini S, Di Natale C, Pirone L, Guariniello S, Scognamiglio PL, Marasco D, Pedone EM, Leone M
Bba-Bioenergetics (ISSN: 0005-2728, 0006-3002print), 2017 Jun 06; 1865(9): 1095-1104.
Impact Factor: 4.28
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* Functional analyses yield detailedinsight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae (106 visite) (PDF 99 visite)
Pirone L, Ripoll-rozada J, Leone M, Ronca R, Lombardo F, Fiorentino G, Andersen JF, Pereira PJB, Arcà B, Pedone E
Jbc Papers, 2017 Jun; N/D: N/D-N/D.
Impact Factor: 4.125
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* Characterization of linear mimetic peptides of Interleukin-22 from dissection of protein interfaces (173 visite)
La Manna S, Scognamiglio PL, Di Natale C, Leone M, Mercurio FA, Malfitano AM, Cianfarani F, Madonna S, Caravella S, Albanesi C, Novellino E, Marasco D
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2017 May 04; N/D: N/D-N/D.
Impact Factor: 3.188
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* Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin (175 visite)
Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Mar 22; 7(1): 307-307.
Impact Factor: 4.122
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* Targeting EphA2-Sam and Its Interactome: Design and Evaluation of Helical Peptides Enriched in Charged Residues (188 visite)
Mercurio FA, Marasco D, Di Natale C, Pirone L, Costantini S, Pedone EM, Leone M
Chembiochem (ISSN: 1439-4227, 1439-7633), 2016 Nov 17; 17(22): 2179-2188.
Impact Factor: 2.847
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* The Sam Domain of EphA2 receptor and its relevance to cancer: a novel challenge for drug discovery? (128 visite)
Mercurio F, Leone M
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2016 Nov 01; N/D: N/D-N/D.
Impact Factor: 3.249
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* Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-beta Oligomer Formation and Cytotoxicity (184 visite)
Sinopoli A, Giuffrida A, Tomasello MF, Giuffrida ML, Leone M, Attanasio F, Caraci F, De Bona P, Naletova I, Saviano M, Copani A, Pappalardo G, Rizzarelli E
Chembiochem (ISSN: 1439-4227, 1439-7633), 2016 Aug 17; 17(16): 1541-1549.
Impact Factor: 2.847
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* Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia (176 visite)
Scognamiglio PL, Di Natale C, Leone M, Cascella R, Cecchi C, Lirussi L, Antoniali G, Riccardi D, Morelli G, Tell G, Chiti F, Marasco D
Oncotarget (ISSN: 1949-2553, 1949-2553electronic), 2016 Aug 1; N/D: N/D-N/D.
Impact Factor: 5.168
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* Self-assembly of PEGylated tetra-phenylalanine derivatives: structural insights from solution and solid state studies (124 visite)
Diaferia C, Mercurio FA, Giannini C, Sibillano T, Morelli G, Leone M, Accardo A
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2016 May 25; 6: 26638-26638.
Impact Factor: 4.259
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* Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process (201 visite)
Calce E, Mercurio F, Leone M, Saviano M, De Luca S
Carbohyd Polym (ISSN: 0144-8617), 2016 Feb; 143: 84-89.
Impact Factor: 4.811
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* Solid-Phase S-Alkylation Promoted by Molecular Sieves (133 visite)
Calce E, Leone M, Mercurio FA, Monfregola L, De Luca S
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2015 Nov 20; 17(22): 5646-5649.
Impact Factor: 6.732
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* Design and activity of a cyclic mini-beta-defensin analog: a novel antimicrobial tool (156 visite)
Scudiero O, Nigro E, Cantisani M, Colavita I, Leone M, Mercurio FA, Galdiero M, Pessi A, Daniele A, Salvatore F, Galdiero S
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2015 Oct 15; 10: 6523-6539.
Impact Factor: 4.32
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* Intrinsically disordered amphiphilic peptides as potential targets in drug delivery vehicles (217 visite)
Vincenzi M, Accardo A, Costantini S, Scala S, Portella L, Trotta A, Ronga L, Guillon J, Leone M, Colonna G, Rossi F, Tesauro D
Mol Biosyst (ISSN: 1742-206x), 2015 Oct 13; 11(11): 2925-2932.
Impact Factor: 2.829
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* Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions (155 visite)
Di Natale C, Scognamiglio PL, Cascella R, Cecchi C, Russo A, Leone M, Penco A, Relini A, Federici L, Di Matteo A, Chiti F, Vitagliano L, Marasco D
The Faseb Journal (ISSN: 1530-6860, 1530-6860electronic), 2015 Sep; 29(9): 3689-3701.
Impact Factor: 5.043
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* A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles (217 visite)
Calce E, Ringhieri P, Mercurio FA, Leone M, Bugatti V, Saviano M, Vittoria V, De Luca S
Rsc Adv (ISSN: 2046-2069), 2015; 5(37): 29573-29576.
Impact Factor: 3.289
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* Conformational ensembles explored dynamically from disordered peptides targeting chemokine receptor CXCR4 (294 visite)
Vincenzi M, Costantini S, Scala S, Tesauro D, Accardo A, Leone M, Colonna G, Guillon J, Portella L, Trotta AM, Ronga L, Rossi F
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2015; 16(6): 12159-12173.
Impact Factor: 3.257
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* Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam (210 visite)
Mercurio FA, Di Natale C, Pirone L, Scognamiglio PL, Marasco D, Pedone EM, Saviano M, Leone M
Chembiochem (ISSN: 1439-4227, 1439-7633), 2015; 16(11): 1629-1636.
Impact Factor: 2.85
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* Cd And Nmr Conformational Studies Of A Peptide Encompassing The Mid Loop Interface Of Ship2-Sam (131 visite)
Mercurio FA, Scognamiglio PL, Di Natale C, Marasco D, Pellecchia M, Leone M
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Nov; 101(11): 1088-1098.
Impact Factor: 2.385
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* Structural insights into and activity analysis of the antimicrobial peptide myxinidin (195 visite)
Cantisani M, Finamore E, Mignogna E, Falanga A, Nicoletti GF, Pedone C, Morelli G, Leone M, Galdiero M, Galdiero S
Antimicrob Agents Ch (ISSN: 0066-4804, 1098-6596), 2014 Sep; 58(9): 5280-5290.
Impact Factor: 4.476
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* G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection (156 visite)
Scognamiglio PL, Di Natale C, Leone M, Poletto M, Vitagliano L, Tell G, Marasco D
Bba-Bioenergetics (ISSN: 0005-2728, 0006-3002print), 2014 Jun; 1840(6): 2050-2059.
Impact Factor: 5.353
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* Conformational Disorder In Phosphopeptides: Solution Studies By Cd And Nmr Techniques (195 visite)
Leone M, Mercurio FA, Vincenzi M, Accardo A, Ringhieri P, Tesauro D, Carrière F, Rossi F
Peptidomics, 2014; 1: 14-21.
Impact Factor: 0
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* Lipidated Peptides Via Post-Synthetic Thioalkylation Promoted By Molecular Sieves (214 visite)
Calce E, Leone M, Monfregola L, De Luca S
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2014; 46(8): 1899-1905.
Impact Factor: 3.293
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* Structure-Activity Relations of Myxinidin, an Antibacterial Peptide Derived from the Epidermal Mucus of Hagfish (260 visite)
Cantisani M, Leone M, Mignogna E, Kampanaraki K, Falanga A, Morelli G, Galdiero M, Galdiero S
Antimicrob Agents Ch (ISSN: 0066-4804, 1098-6596), 2013 Nov; 57(11): 5665-5673.
Impact Factor: 4.451
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* Heterotypic Sam-Sam Association Between Odin-Sam1 And Arap3-Sam: Binding Affinity And Structural Insights (126 visite)
Mercurio FA, Marasco D, Pirone L, Scognamiglio PL, Pedone E, Pellecchia M, Leone M
Chembiochem (ISSN: 1439-4227, 1439-9422, 1439-7633), 2013 Jan 2; 14(1): 100-106.
Impact Factor: 2.92
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* Chemical Modifications Of Peptide Sequences Via S-Alkylation Reaction (140 visite)
Calce E, Leone M, Monfregola L, De Luca S
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2013; 15(20): 5354-5357.
Impact Factor: 6.324
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* Solution conformational features and interfacial properties of an intrinsically disordered peptide coupled to alkyl chains: A new class of peptide amphiphiles (170 visite)
Accardo A, Leone M, Tesauro D, Aufiero R, Bénarouche A, Cavalier JF, Longhi S, Carriere F, Rossi F
Mol Biosyst (ISSN: 1742-206x), 2013; 9(6): 1401-1410.
Impact Factor: 3.183
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* Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells (125 visite)
Lirussi L, Antoniali G, Vascotto C, D'Ambrosio C, Poletto M, Romanello M, Marasco D, Leone M, Quadrifoglio F, Bhakat KK, Scaloni A, Tell G
Mol Biol Cell (ISSN: 1059-1524), 2012 Oct 15; 23(20): 4079-4096.
Impact Factor: 4.803
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* Postsynthetic modification of peptides via chemoselective N-alkylation of their side chains (211 visite)
Monfregola L, Leone M, Calce E,  de Luca S
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2012 Apr 6; 14(7): 1664-1667.
Impact Factor: 6.142
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* Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting (220 visite)
Scarí G, Porta F, Fascio U, Avvakumova S, Dal Santo V, De Simone M, Saviano M, Leone M, Del Gatto A, Pedone C, Zaccaro L
Bioconjug Chem (ISSN: 1520-4812, 1043-1802, 1520-4812electronic), 2012 Mar 21; 23(3): 340-349.
Impact Factor: 4.58
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* Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor (149 visite)
Mercurio FA, Marasco D, Pirone L, Pedone E, Pellecchia M,  Leone M
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2012 Mar 13; 51(10): 2136-2145.
Impact Factor: 3.377
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* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (186 visite)
Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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* Design and NMR Studies of Cyclic Peptides Targeting the N-Terminal Domain of the Protein Tyrosine Phosphatase YopH (237 visite)
Barile E, Leone M, Barile E, Dahl R, Pellecchia M
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2011 Jan; 77(1): 12-19.
Impact Factor: 2.282
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* Chemical modification of pectin: Environmental friendly process for new potential material development (122 visite)
Monfregola L, Leone M, Vittoria V, Amodeo P, De Luca S
Polym Chem (ISSN: 1759-9954), 2011; 2(4): 800-804.
Impact Factor: 5.321
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* NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH (154 visite)
Leone M, Barile E, Vazquez J, Mei A, Guiney D, Dahl R, Pellecchia M
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2010 Jul; 76(1): 10-16.
Impact Factor: 2.527
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* Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex (178 visite)
Santelli E, Leone M, Li C, Fukushima T, Preece NE, Olson AJ, Ely KR, Reed JC, Pellecchia M, Liddington RC, Matsuzawa S-I
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2005 Oct 7; 280(40): 34278-34287.
Impact Factor: 5.854
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* Solution structure and backbone dynamics of the K18G/R82E Alicyclobacillus acidocaldarius thioredoxin mutant: A molecular analysis of its reduced thermal stability (142 visite)
Leone M, Di Lello P, Ohlenschläger O, Pedone E, Bartolucci S, Rossi M, Di Blasio B, Pedone C, Saviano M, Isernia C, Fattorusso R
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2004 May 25; 43(20): 6043-6058.
Impact Factor: 4.008
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* NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (195 visite)
Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.
Impact Factor: 3.992
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* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site (152 visite)
Oliva R, Leone M, Falcigno L, D'Auria G, Dettin M, Scarinci C, Di Bello C, Paolillo L
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2002 Mar 15; 8(6): 1467-1473.
Impact Factor: 4.238
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