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NomeGiuseppe Pappalardo
AreaRicerca e Sviluppo
QualificaPrimo Ricercatore
SedeCatania
Indirizzoc/o Dipartimento di Scienze Chimiche Viale Andrea Doria 6, 95125 Catania - Italy
E-mailgiuseppe.pappalardocnr.it
Telefono ufficio+39 095-7338420

GRADUATION: degree in Biological Sciences cum laude (1986), University of Catania, Italy. EDUCATION and TRAINING: qualification as a Biologist (1987); Research fellowship at CNR (1989-91); Researcher at CNR (1994). PRESENT POSITION: Senior Researcher at CNR (2001); Appointed Responsible of the Research unit of Catania of the CNR-IBB (2002-2017); contract Professor Laboratory of chemical Synthesis of Proteins Master (Magistral) Degree Course in Biomolecular Chemistry (since the A. Y. 2004/2005). INSTITUTION VISITED (STUDY TOURS): University of Saarland, Germany (1997), University of Debrecen, Hungary (2004, 2006, 2008,). Project Leaderships: Miur-Grant n196 (2004); Miur-FIRB RBIN04L28Y (2006); Miur-FIRB RBPR05JH2P (2009); Miur-FIRB RBNE08HWLZ (2011). RESEARCH INTERESTS: synthesis, conformational analysis, NMR spectroscopy and metal ion interactions of peptides and glycopeptides. Cell and tissue delivery of biologically active compounds. He is presently studying the role of metal-peptide interactions in neurodegenerative disorders and type 2 diabetes. He is co-author of more than 95 publications on international journals. Collaborations: University of Catania, (Italy); University of Naples Federico II (Italy); Wyeth Lederle S. p. a., Catania Site; ST-Microelectronics, Catania Site; University of Debrecen, (Ungheria); Harvard Medical School, (USA)


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Bibliografia
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* Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases (61 visite)
Lanza V, Milardi D, Di Natale G, Pappalardo G
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2018 Feb 12; 25(4): 525-539.
Impact Factor: 3.249
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A Metalloporphyrin-Peptide Conjugate as an Effective Inhibitor of Amyloid-β Peptide Fibrillation and Cytotoxicity (75 visite)
Villari V, Tosto R, Di Natale G, Sinopoli A, Tomasello M, Lazzaro S, Micali N, Pappalardo G
Chem Select (ISSN: 2365-6549), 2017 Oct; 2(28): 9122-9129.
Impact Factor: 4.225
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Tau-peptide fragments and their copper(II) complexes: Effects on Amyloid-beta aggregation (100 visite)
Di Natale G, Bellia F, Sciacca F, Campagna T, Pappalardo G
Inorganica Chimica Acta, 2017 Sep; N/D: N/D-N/D.
Impact Factor: 2.002
Dettagli    Esporta in BibTeX    Esporta in EndNote

* New comprehensive studies of a gold(III) Dithiocarbamate complex with proven anticancer properties: Aqueous dissolution with cyclodextrins, pharmacokinetics and upstream inhibition of the ubiquitin-proteasome pathway (103 visite)
Tomasello MF, Nardon C, Lanza V, Di Natale G, Pettenuzzo N, Salmaso S, Milardi D, Caliceti P, Pappalardo G, Fregona D
Eur J Med Chem (ISSN: 1768-3254electronic, 0223-5234linking), 2017 Jun 19; 138: 115-127.
Impact Factor: 4.519
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies (72 visite)
Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Sciacca MFM, Sinopoli A, Milardi D, Pappalardo G, De Spirito M, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G
Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2017 Apr 22; N/D: N/D-N/D.
Impact Factor: 5.168
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study (113 visite)
Santoro AM, Monaco I, Attanasio F, Lanza V, Pappalardo G, Tomasello MF, Cunsolo A, Rizzarelli E, De Luigi A, Salmona M, Milardi D
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2016 Sep 16; 6: 33444-33444.
Impact Factor: 4.259
Dettagli    Esporta in BibTeX    Esporta in EndNote

* New Insight in Copper-Ion Binding to Human Islet Amyloid: The Contribution of Metal-Complex Speciation To Reveal the Polypeptide Toxicity (106 visite)
Magri A, La Mendola D, Nicoletti VG, Pappalardo G, Rizzarelli E
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2016 Sep 5; 22(37): 13287-13300.
Impact Factor: 5.317
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-beta Oligomer Formation and Cytotoxicity (115 visite)
Sinopoli A, Giuffrida A, Tomasello MF, Giuffrida ML, Leone M, Attanasio F, Caraci F, De Bona P, Naletova I, Saviano M, Copani A, Pappalardo G, Rizzarelli E
Chembiochem (ISSN: 1439-7633electronic, 1439-4227linking), 2016 Aug 17; 17(16): 1541-1549.
Impact Factor: 2.847
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) coordination properties of the Abeta(1-16)2 peptidomimetic: an experimental evidence of intermolecular macrochelate complex species in the abeta dimer (76 visite)
Di Natale G, Sinopoli A, Grenacs A, Sanna D, Sovago I, Pappalardo G
New J Chem, 2016; 40: 10274-10284.
Impact Factor: 3.227
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The N-Terminal Peptides of the Three Human Isoforms of the Mitochondrial Voltage-Dependent Anion Channel Have Different Helical Propensities (167 visite)
Guardiani C, Scorciapino MA, Amodeo GF, Grdadolnik J, Pappalardo G, De Pinto V, Ceccarelli M, Casu M
Biochemistry (ISSN: 1520-4995electronic, 0006-2960linking), 2015 Sep 15; 54(36): 5646-5656.
Impact Factor: 2.876
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Monomeric ss-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons (175 visite)
Giuffrida ML, Tomasello MF, Pandini G, Caraci F, Battaglia G, Busceti C, Di Pietro P, Pappalardo G, Attanasio F, Chiechio S, Bagnoli S, Nacmias B, Sorbi S, Vigneri R, Rizzarelli E, Nicoletti F, Copani A
Front Cell Neurosci (ISSN: 1662-5102electronic, 1662-5102linking), 2015 Aug 7; 9(AUGUST): 297-297.
Impact Factor: 4.609
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Neuroprotective effects of the monoamine oxidase inhibitor Tranylcypromine and its amide derivatives against Abeta(1-42)-induced toxicity (176 visite)
Caraci F, Pappalardo G, Basile L, Giuffrida A, Copani A, Tosto R, Sinopoli A, Giuffrida ML, Pirrone E, Drago F, Pignatello R, Guccione S
Eur J Pharmacol (ISSN: 1879-0712electronic, 0014-2999linking), 2015 Jul 7; 764: 256-263.
Impact Factor: 2.73
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Cross-Talk Between the Octarepeat Domain and the Fifth Binding Site of Prion Protein Driven by the Interaction of Copper(II) with the N-terminus (113 visite)
Di Natale G, Turi I, Pappalardo G, Sóvágó I, Rizzarelli E
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2015 Mar 2; 21(10): 4071-4084.
Impact Factor: 5.771
Dettagli    Esporta in BibTeX    Esporta in EndNote

* On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides (143 visite)
Tomasello MF, Sinopoli A, Pappalardo G
J Diabetes Res (ISSN: 2314-6745print, 2314-6753online), 2015; articleID918573: 918573-918573.
Impact Factor: 2.431
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The role of copper(II) in the aggregation of human amylin (189 visite)
Sinopoli A, Magri A, Milardi D, Pappalardo M, Pucci P, Flagiello A, Titman JJ, Nicoletti VG, Caruso G, Pappalardo G, GrassoG
Metallomics (ISSN: 1756-591xelectronic, 1756-5901linking), 2014 Oct; 6(10): 1841-1852.
Impact Factor: 3.585
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides (321 visite)
Tomasello MF, Sinopoli A, Attanasio F, Giuffrida ML, Campagna T, Milardi D, Pappalardo G
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2014 Jun 23; 81: 442-455.
Impact Factor: 3.447
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The effect of non-coordinating side chains on the metal binding affinities of peptides of histidine (163 visite)
Turi I, DSanna D, Garribba E, Pappalardo G, Sóvágó I
Polyhedron (ISSN: 0277-5387), 2013 Oct 7; 62: 7-17.
Impact Factor: 2.047
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Probing the residual structure in avian prion hexarepeats by CD, NMR and MD techniques (153 visite)
Russo L, Raiola L, Campitiello MA, Magrì A, Fattorusso R, Malgieri G, Pappalardo G, La Mendola D, Isernia C
Molecules (ISSN: 1420-3049, 1420-3049electronic), 2013 Sep; 18(9): 11467-11484.
Impact Factor: 2.095
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Affinity, speciation, and molecular features of copper(II) complexes with a prion tetraoctarepeat domain in aqueous solution: insights into old and new results (126 visite)
Di Natale G, Osz K, Kállay C, Pappalardo G, Sanna D, Impellizzeri G, Sóvágó I, Rizzarelli E
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2013 Mar 11; 19(11): 3751-3761.
Impact Factor: 5.696
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) and zinc(II) dependent effects on A beta 42 aggregation: a CD, Th-T and SFM study (159 visite)
Attanasio F, De Bona P, Cataldo S, Sciacca MFM, Milardi D, Pignataro B, Pappalardo G
New J Chem (ISSN: 1144-0546), 2013; 37(4): 1206-1215.
Impact Factor: 3.159
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Shared and distinct features of beta-amyloid peptides (126 visite)
Giuffrida M, Caraci F, Tomasello F, Pappalardo G, Rizzarelli E, Nicoletti F, Copani AG
Society For Neuroscience Abstract Viewer And Itinerary Planner, 2013; 43: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Metal ions affect insulin-degrading enzyme activity (110 visite)
Grasso G, Salomone F, Tundo GR, Pappalardo G, Ciaccio C, Spoto G, Pietropaolo A, Coletta M, Rizzarelli E
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Dec; 117: 351-358.
Impact Factor: 3.197
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of Cu 2+ with prion family peptide fragments: Considerations on affinity, speciation and coordination (242 visite)
Arena G, La Mendola D, Pappalardo G, Sovago I, Rizzarelli E
Coord Chem Rev (ISSN: 0010-8545), 2012 Oct; 256(19-20): 2202-2218.
Impact Factor: 11.016
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(ii) Coordination Properties Of The Integrin Ligand Sequence Phsrn And Its New Beta-Cyclodextrin Conjugates (160 visite)
Magrì A, D'Alessandro F, Di Stefano DA, Campagna T, Pappalardo G, Impellizzeri G, La Mendola D
Journal Of Inorganic Biochemistry, 2012 Sep; 113: 15-24.
Impact Factor: 3.444
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Mixed metal copper(II)-nickel(II) and copper(II)-zinc(II) complexes of multihistidine peptide fragments of human prion protein (155 visite)
Jószai V, Turi I, Kállay C, Pappalardo G, Di Natale G, Rizzarelli E, Sóvágó I
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Jul; 112: 17-24.
Impact Factor: 3.197
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(ii) Interaction With Amyloid-Beta: Affinity And Speciation (146 visite)
Arena G, Pappalardo G, Sovago I, Rizzarelli E
Coord Chem Rev (ISSN: 0010-8545), 2012 Jan; 256(1-2): 3-12.
Impact Factor: 11.016
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Monomeric beta-amyloid activities relay on specific receptor engagement (106 visite)
Giuffrida M, Tomasello F, Caraci F, Pandini G, Chiechio S, Pappalardo G, Vigneri R, Rizzarelli E, Nicoletti F, Copani AG
Society For Neuroscience Abstract Viewer And Itinerary Planner, 2012; 42: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) complexes of rat amylin fragments (138 visite)
Kállay C, Dávid A, Timári S, Nagy EM, Sanna D, Garribba E, Micera G, De Bona P, Pappalardo G, Rizzarelli E, Sóvágó I
Dalton Trans (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2011 Oct 14; 40(38): 9711-9721.
Impact Factor: 3.838
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Zn2+'s ability to alter the distribution of Cu2+ among the available binding sites of A beta(1-16)-polyethylenglycol-ylated peptide: Implications in Alzheimer's disease (116 visite)
Damante CA, Ösz K, Nagy Z, Grasso G, Pappalardo G, Rizzarelli E, Sóvágó I
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2011 Jun 20; 50(12): 5342-5350.
Impact Factor: 4.601
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The effect of point mutations on copper(II) complexes with peptide fragments encompassing the 106-114 region of human prion protein (150 visite)
Kállay C, Turi I, Timári S, Nagy Z, Sanna D, Pappalardo G, De Bona P, Rizzarelli E, Sóvágó I
Monatshefte Fur Chemie (ISSN: 0026-9247), 2011 Apr; 142(4): 411-419.
Impact Factor: 1.532
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein (127 visite)
Vagliasindi LI, Arena G, Bonomo RP, Pappalardo G, Tabbì G
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2011 Mar 21; 40(11): 2441-2450.
Impact Factor: 3.838
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(I) and Copper(II) Inhibit A beta Peptides Proteolysis by Insulin-Degrading Enzyme Differently: Implications for Metallostasis Alteration in Alzheimer's Disease (168 visite)
Grasso G, Pietropaolo A, Spoto G, Pappalardo G, Tundo GR, Ciaccio C, Coletta M, Rizzarelli E
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Feb 25; 17(9): 2752-2762.
Impact Factor: 5.925
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A new function for beta-amyloid monomers (120 visite)
Giuffrida M-, Tomasello F, Caraci F, Pandini G, Chiechio S, Battaglia G, De Bona P, Pappalardo G, Vigneri R, Nicoletti F, Rizzarelli E, Copani AG
Society For Neuroscience Abstract Viewer And Itinerary Planner, 2011; 41: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Inorganic Side of Alzheimer's Disease (117 visite)
Pappalardo G, Milardi D, Rizzarelli E, Sovago I
Neurodegeneration (ISSN: 2041-3203), 2011; (7): N/D-N/D.
Impact Factor: 2.082
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Membrane interactions and conformational preferences of human and avian prion N-terminal tandem repeats: The role of copper(II) ions, pH, and membrane mimicking environments (153 visite)
Di Natale G, Pappalardo G, Milardi D, Sciacca MF, Attanasio F, La Mendola D, Rizzarelli E
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 Nov 4; 114(43): 13830-13838.
Impact Factor: 3.603
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Nickel(ii) and mixed metal complexes of amyloid-β N-terminus (148 visite)
Józsa E, Osz K, Kállay C, de Bona P, Damante CA, Pappalardo G, Rizzarelli E, Sóvágó I
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2010 Sep 14; 39(30): 7046-7053.
Impact Factor: 3.647
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Nickel(II) complexes of the multihistidine peptide fragments of human prion protein (119 visite)
Turi I, Kállay C, Szikszai D, Pappalardo G, Di Natale G, De Bona P, Rizzarelli E, Sóvágó I
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2010 Sep; 104(8): 885-891.
Impact Factor: 3.317
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Aggregation properties of the peptide fragments derived from the 17-29 region of the human and rat IAPP: A comparative study with two PEG-conjugated variants of the human sequence (176 visite)
Mazzaglia A, Micali N, Scolaro LM, Attanasio F, Magrí A, Pappalardo G, Villari V
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 Jan 21; 114(2): 705-713.
Impact Factor: 3.603
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films - Effects on fibroblast spreading (168 visite)
Satriano C, Messina GM, Marino C, Aiello I, Conte E, La Mendola D, Distefano DA, D'Alessandro F, Pappalardo G, Impellizzeri G
J Colloid Interface Sci (ISSN: 1095-7103electronic, 0021-9797linking), 2010 Jan 15; 341(2): 232-239.
Impact Factor: 3.068
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Basic understanding of the activities of beta-amyloid (A beta) monomers (115 visite)
Giuffrida M, Tomasello F, Caraci F, Pappalardo G, Rizzarelli E, Nicoletti F, Copani AG
Society For Neuroscience Abstract Viewer And Itinerary Planner, 2010; 40: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Different Interactions Of Human And Avian Prion Proteins N-Terminal Tandem Repeat Peptides And Their Copper (ii) Complexes With Model Membranes (128 visite)
Di Natale G, Pappalardo G, Milardi D, Sciacca MFM, Attanasio F, La Mendola D, Rizzarelli E
Journal Of Chemical Physics, 2010; 114: 13830-13838.
Impact Factor: 2.028
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Nickel (ii) And Mixed Metal Complexes Of Amyloid-B N-Terminus. Results Of Potentiometric And Spectroscopic Studies On The Binary Nickel (ii) And Mixed Metal Nickel (ii)-Copper (ii) And Nickel (ii)-Copper (ii)-Zinc (ii) Complexes Of Peptide Fragments (174 visite)
Jozsa E, Hosz K, Kallay C, De Bona P, Damante CA, Pappalardo G, Rizzarelli E, Sovago I
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2010; 39(30): 7046-7053.
Impact Factor: 3.647
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The monomer state of beta-amyloid: where the Alzheimer's disease protein meets physiology (143 visite)
Giuffrida ML, Caraci F, De Bona P, Pappalardo G, Nicoletti F, Rizzarelli E, Copani A
Rev Neurosci (ISSN: 0334-1763), 2010; 21(2): 83-93.
Impact Factor: 2.047
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Metal Loading Capacity Of Abeta N-Terminus: A Combined Potentiometric And Spectroscopic Study Of Zinc (ii) Complexes With Abeta (1-16), Its Short Or Mutated Peptide Fragments And Its Polyethylene Glycol-Ylated Analogue (138 visite)
Damante CA, Osz K, Nagy Z, Pappalardo G, Grasso G, Impellizzeri G, Rizzarelli E, Sóvágó I
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2009 Nov 2; 48(21): 10405-10415.
Impact Factor: 4.657
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Beta-Amyloid Monomers Are Neuroprotective (169 visite)
Giuffrida ML, Caraci F, Pignataro B, Cataldo S, De Bona P, Bruno V, Molinaro G, Pappalardo G, Messina A, Palmigiano A, Garozzo D, Nicoletti F, Rizzarelli E, Copani A
J Neurosci (ISSN: 1529-2401, 0270-6474), 2009 Sep 26; 29(34): 10582-10587.
Impact Factor: 3.669
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Prion Proteins Leading to Neurodegeneration (vol 5, pg 579, 2008) (93 visite)
La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
Current Alzheimer Research (ISSN: 1567-2050), 2009 Jun; 6(3): N/D-N/D.
Impact Factor: 4.971
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Interaction Of Copper (ii) With The Prion Peptide Fragment Huprp (76-114) Encompassing Four Histidyl Residues Within And Outside The Octarepeat Domain (112 visite)
Di Natale G, Osz K, Nagy Z, Sanna D, Micera G, Pappalardo G, Sovago I, Rizzarelli E
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2009 May 4; 48(9): 4239-4250.
Impact Factor: 4.657
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Design And Synthesis Of New Trehalose-Conjugated Pentapeptides As Inhibitors Of Abeta (1-42) Fibrillogenesis And Toxicity (182 visite)
De Bona P, Giuffrida ML, Caraci F, Copani A, Pignataro B, Attanasio F, Cataldo S, Pappalardo G, Rizzarelli E
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 220-228.
Impact Factor: 1.807
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) complexes with an avian prion N-terminal region and their potential SOD-like activity (139 visite)
La Mendola D, Bonomo RP, Caminati S, Di Natale G, Emmi SS, Hansson O, Maccarrone G, Pappalardo G, Pietropaolo A, Rizzarelli E
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2009 Feb; 103(2): 195-204.
Impact Factor: 3.252
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Monomers of beta-amyloid protein are endowed with neuroprotective activity (113 visite)
Giuffrida M, Caraci F, Molinaro G, Cataldo S, Pignataro B, Bruno V, De Bona P, Pappalardo G, Messina A, Palmigiano A, Garozzo D, Nicoletti F, Rizzarelli E, Copani AG
Society For Neuroscience Abstract Viewer And Itinerary Planner, 2009; 39: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Prion proteins leading to neurodegeneration (140 visite)
La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
Current Alzheimer Research (ISSN: 1567-2050), 2008 Dec; 5(6): 579-590.
Impact Factor: 4.132
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) binding to two novel histidine-containing model hexapeptides: evidence for a metal ion driven turn conformation (147 visite)
Di Natale G, Damante CA, Nagy Z, Osz K, Pappalardo G, Rizzarelli E, Sóvágó I
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2008 Nov; 102(11): 2012-2019.
Impact Factor: 3.133
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Metal Loading Ability Of Beta-Amyloid N-Terminus: A Combined Potentiometric And Spectroscopic Study Of Copper (ii) Complexes With Beta-Amyloid (1-16), Its Short Or Mutated Peptide Fragments, And Its Polyethylene Glycol (peg)-Ylated Analogue (130 visite)
Damante CA, Ösz K, Nagy Z, Pappalardo G, Grasso G, Impellizzeri G, Rizzarelli E, Sóvágó I
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2008 Oct 20; 47(20): 9669-9683.
Impact Factor: 4.147
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Studies of nitric oxide interaction with mono- and dinuclear copper(II) complexes of prion protein bis-octarepeat fragments (138 visite)
Bonomo RP, Pappalardo G, Rizzarelli E, Tabbì G, Vagliasindi LI
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2008 Sep 7; (29): 3805-3816.
Impact Factor: 3.58
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Designing trehalose-conjugated peptides for the inhibition of Alzheimer's A beta oligornerization and neurotoxicity (138 visite)
De Bona P, Giuffrida ML, Attanasio F, Copani A, Pignataro B, Cataldo S, Rizzarelli E, Pappalardo G
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Metal ion interactions within the 1-16 N-terminal region of beta-amyloid (103 visite)
Damante C, Osz K, Nagy Z, Pappalardo G, Grasso G, Impellizzeri G, Rizzarelli E, Sovago I
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Carcinine-beta-cyclodextrin derivatives as scavenger entities of (OH) radicals and SOD-like properties of their copper(II) complexes (113 visite)
Bonomo RP, D'Alessandro F, Grasso G, Impellizzeri G, Pappalardo G, Rizzarelli E, Tabbì G
Inorg Chim Acta (ISSN: 0020-1693), 2008 May 5; 361(6): 1705-1714.
Impact Factor: 1.94
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Unveiling the role of histidine and tyrosine residues on the conformation of the avian prion hexarepeat domain (105 visite)
Pietropaolo A, Muccioli L, Zannoni C, La Mendola D, Maccarrone G, Pappalardo G, Rizzarelli E
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2008 Apr 24; 112(16): 5182-5188.
Impact Factor: 4.189
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A Peptide Containing Residues 26-44 Of Tau Protein Impairs Mithocondrial Oxodative Phosphorylation Acting At The Level Of The Adenine Nucleotide Translocator (76 visite)
Atlante A, Amadoro G, Bobba A, De Bari L, Corsetti V, Pappalardo G, Marra E, Calissano P, Passarella S
Biochimica Et Biophysica Acta, 2008; 1777: 1289-1300.
Impact Factor: 1.722
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A peptide containing residues 26-44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator (119 visite)
Atlante A, Amadoro G, Bobba A, de Bari L, Corsetti V, Pappalardo G, Marra E, Calissano P, Passarella S
Biochim Biophys Acta (ISSN: 0005-2728, 0006-3002print, 0006-3002linking), 2008; 1777(10): 1289-1300.
Impact Factor: 4.447
Dettagli    Esporta in BibTeX    Esporta in EndNote

* An NMR and molecular dynamics investigation of the avian prion hexarepeat conformational features in solution (136 visite)
Pietropaolo A, Raiola L, Muccioli L, Tiberio G, Zannoni C, Fattorusso R, Isernia C, La Mendola D, Pappalardo G, Rizzarelli E
Chemical Physics Letters (ISSN: 0009-2614), 2007 Jul 6; 442(1-3): 110-118.
Impact Factor: 2.207
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Determination of the conformation of the human VDAC1 N-terminal peptide, a protein moiety essential for the functional properties of the pore (109 visite)
De Pinto V, Tomasello F, Messina A, Guarino F, Benz R, La Mendola D, Magrì A, Milardi D, Pappalardo G
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 7; 8(7): 744-756.
Impact Factor: 3.446
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Nitrogen oxide interaction with copper complexes formed by small peptides belonging to the prion protein octa-repeat region (145 visite)
Bonomo RP, Pappalardo G, Rizzarelli E, Santoro AM, Tabbì G, Vagliasindi LI
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2007 Apr 14; (14): 1400-1408.
Impact Factor: 3.212
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) interaction with prion peptide fragments encompassing histidine residues within and outside the octarepeat domain: speciation, stability constants and binding details (135 visite)
Osz K, Nagy Z, Pappalardo G, Di Natale G, Sanna D, Micera G, Rizzarelli E, Sóvágó I
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2007; 13(25): 7129-7143.
Impact Factor: 5.33
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Environmental factors differently affect human and rat IAPP: Conformational preferences and membrane interactions of IAPP17-29 peptide derivatives (145 visite)
Pappalardo G, Milardi D, Magrì A, Attanasio F, Impellizzeri G, La Rosa C, Grasso D, Rizzarelli E
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2007; 13(36): 10204-10215.
Impact Factor: 5.33
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Modelling IAPP's membrane interaction: Conformational preferences and membrane activity of IAPP17-29 peptide derivatives (122 visite)
Pappalardo G, Milardi D, Magna A, Attanasio F, Impellizzeri G, La Rosa C, Grasso D, Rizzarelli E
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(4): N/D-N/D.
Impact Factor: 2.389
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Transition metal complexes of terminally protected peptides containing histidyl residues (155 visite)
Joszal V, Nagy Z, Osz K, Sanna D, Di Natale G, La Mendola D, Pappalardo G, Rizzarelli E, Sovago I
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2006 Sep; 100(8): 1399-1409.
Impact Factor: 2.654
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Conformational properties and functional role of VDAC N-terminal peptide (98 visite)
De Pinto V, Messina A, Aiello R, Tomasello F, La Mendola D, Magrì A, Milardi D, Pappalardo G
Understanding Biology Using Peptides, 2006; N/D: N/D-N/D.
Impact Factor: 2.614
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Spectroscopic characterization of PEG-amylin derivatives (105 visite)
Impellizzeri G, La Mendola D, Magrì A, Maccarrone G, Pappalardo G, Rizzarelli E
Understanding Biology Using Peptides, 2006; N/D: N/D-N/D.
Impact Factor: 2.614
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Environmental effects on a prion's helix II domain: copper(II) and membrane interactions with PrP180-193 and its analogues (101 visite)
Grasso D, Grasso G, Guantieri V, Impellizzeri G, La Rosa C, Milardi D, Micera G, Osz K, Pappalardo G, Rizzarelli E, Sanna D, Sovago I
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2005 Dec 23; 12(2): 537-547.
Impact Factor: 4.907
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) interaction with unstructured prion domain outside the octarepeat region: Speciation, stability, and binding details of copper(II) complexes with PrP106-126 peptides (153 visite)
Di Natale G, Grasso G, Impellizzeri G, La Mendola D, Micera G, Mihala N, Nagy Z, Osz K, Pappalardo G, Rigó V, Rizzarelli E, Sanna D, Sóvágó I
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2005 Oct 3; 44(20): 7214-7225.
Impact Factor: 3.851
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) complexes with chicken prion repeats: Influence of proline and tyrosine residues on the coordination features (110 visite)
La Mendola D, Bonomo RP, Impellizzeri G, Maccarrone G, Pappalardo G, Pietropaolo A, Rizzarelli E, Zito V
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2005 Sep; 10(5): 463-475.
Impact Factor: 3.224
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Conformational properties of peptide fragments homologous to the 106-114 and 106-126 residues of the human prion protein: a CD and NMR spectroscopic study (123 visite)
Di Natale G, Impellizzeri G, Pappalardo G
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2005 Feb 7; 3(3): 490-497.
Impact Factor: 2.547
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A re-investigation of copper coordination in the octa-repeats region of the prion protein (118 visite)
Bonomo RP, Cucinotta V, Giuffrida A, Impellizzeri G, Magrì A, Pappalardo G, Rizzarelli E, Santoro AM, Tabbì G, Vagliasindi LI
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2005 Jan 7; (1): 150-158.
Impact Factor: 3.003
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Conformational properties and functional role of the VDAC N-terminal peptide (84 visite)
De Pinto V, Messina A, Aiello R, Tomasello F, La Mendola D, Magri A, Milardi D, Pappalardo G
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2005; 80(4): N/D-N/D.
Impact Factor: 2.545
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Metal ion driven turn conformation in two histidine-containing short peptides (137 visite)
Pappalardo G, Campagna T, Di Natale G, Grasso G, Impellizzeri G, Rizzarelli E
Peptides 2004 Proceedings, 2005; N/D: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

* PEG-amylin fragments as models for conformational studies (127 visite)
Impellizzeri G, La Mendola D, Magrì A, Pappalardo G, Rizzarelli E
Peptides 2004 Proceedings, 2005; 10: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Spectroscopic characterization of PEG amylin derivatives (107 visite)
La Mendola D, Magrì A, Pappalardo G, Impellizzeri G, Maccarrone G, Rizzarelli E
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2005; 80(4): N/D-N/D.
Impact Factor: 2.545
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural Characterization Of Functionalized B-Cyclodestrins (112 visite)
Saviano M, Vitale RM, Pedone C, Iacovino R, La Mendola D, Pappalardo G, Vecchio G, Rizzarelli E
Acta Crystallogr D Biol Crystallogr, 2005; N/D: N/D-N/D.
Impact Factor: 2.069
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis And Structural Characterisation Of Two Novel Diastereoisomeric Naproxen-Appended Beta-Cyclodextrin Derivatives (102 visite)
Impellizzeri G, D'Alessandro F, Pappalardo G, Tringali C
J Incl Phenom (ISSN: 0923-0750), 2005; 51(3-4): 173-180.
Impact Factor: 1.02
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) complexes of peptide fragments of the prion protein. Conformation changes induced by copper(II) and the binding motif in C-terminal protein region (133 visite)
Brown DR, Guantieri V, Grasso G, Impellizzeri G, Pappalardo G, Rizzarelli E
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2004 Jan; 98(1): 133-143.
Impact Factor: 2.225
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) binding of prion protein's octarepeat model peptides (156 visite)
Pappalardo G, Impellizzeri G, Campagna T
Inorg Chim Acta (ISSN: 0020-1693), 2004; 357(1): 185-194.
Impact Factor: 1.554
Dettagli    Esporta in BibTeX    Esporta in EndNote

* PEG-AMYLIN FRAGMENTS AS MODELS FOR CONFORMATIONAL STUDIES (122 visite)
La Mendola D, Magrì A, Pappalardo G, Rizzarelli E, Impellizzeri G
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2004; 10: N/D-N/D.
Impact Factor: 1.652
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A thermodynamic and spectroscopic study on the copper(II) complexes with hexarepeats fragments of the avian prion protein (133 visite)
La Mendola D, Bonomo R, Maccarrone G, Pappalardo G, Rizzarelli E
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2003 Jul 15; 96(1): N/D-N/D.
Impact Factor: 2.343
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Metal binding to prion protein (123 visite)
Bonomo RP, Grasso D, Grasso G, Guantieri V, Impellizzeri G, La Rosa C, Milardi D, Pappalardo G, Tabbì G, Rizzarelli E
Metal-Ligand Interactions - Molecular Nano- Micro- And Macro-Systems In Complex Environments, 2003 Jan 01; 116: 21-39.
Impact Factor: 5.664
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Functional Mimics Of Cu, Zn-Superoxide Dismutase Enzymes, In Metal-Ligand Interactions In Nano-, Micro-, And Macro-Systems In Complex Environments (96 visite)
Bonomo RP, Impellizzeri G, La Mendola D, Maccarone G, Pappalardo G, Santoro A, Tabbì G, Vecchio G, Rizzarelli E
In Complex Environmentsmetal Ligand Interactions (ISSN: 1568-2609, 1568-8260), 2003 Jan; 116: 41-63.
Impact Factor: 5.664
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Functional mimics of Cu, Zn-superoxide dismutase enzymes (111 visite)
Bonomo RP, Impellizzeri G, La Mendola D, Maccarone G, Pappalardo G, Santoro A, Tabbì G, Vecchio G, Rizzarelli E
In Complex Environmentsmetal Ligand Interactions (ISSN: 1568-2609, 1568-8260), 2003; 116: 41-63.
Impact Factor: 5.664
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The interaction of a peptide with a scrambled hydrophobic/hydrophilic sequence (Pro-Asp-Ala-Asp-Ala-His-Ala-His-Ala-His-Ala-Ala-Ala-His-Gly) (PADH) with DPPC model membranes: A DSC study (108 visite)
Grasso D, Milardi D, La Rosa C, Impellizzeri G, Pappalardo G
Thermochim Acta (ISSN: 0040-6031), 2002 Jul 15; 390(1-2): 73-78.
Impact Factor: 0.974
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Copper(II) and nickel(II) binding modes in a histidine-containing model dodecapeptide (119 visite)
Pappalardo G, Impellizzeri G, Bonomo RP, Campagna T, Grasso G, Saita MG
New J Chem (ISSN: 1144-0546), 2002; 26(5): 593-600.
Impact Factor: 2.06
Dettagli    Esporta in BibTeX    Esporta in EndNote

Copper(II) binding modes in the prion octapeptide PHGGGWGQ: A spectroscopic and voltammetric study (177 visite)
Bonomo RP, Imperllizzeri G, Pappalardo G, Rizzarelli E, Tabbì G
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2000 Nov 17; 6(22): 4195-4202.
Impact Factor: 4.698
Dettagli    Esporta in BibTeX    Esporta in EndNote

Erratum: Solid state and solution conformation of 6-{4-[N-tert- butoxycarbonyl-N-(N'-ethyl)propanamide]imidazolyl}-6- deoxycyclomaltoheptaose: Evidence of self-inclusion of the boc group within the β-cyclodextrin cavity (European Journal of Organic Chemistry (2000) (1065-1076)) (118 visite)
Impellizzeri G, Pappalardo G, D'Alessandro F, Rizzarelli E, Saviano M, Iacovino R, Benedetti E, Pedone C
Eur J Org Chem (ISSN: 1434-193x), 2000; (12): 2345-2345.
Impact Factor: 2.15
Dettagli    Esporta in BibTeX    Esporta in EndNote

Solid state and solution conformation of 6-{4-[N-tert-butoxycarbonyl-N- (N'-ethyl)propanamide]imidazolyl}-6-deoxycyclomaltoheptaose: Evidence of self-inclusion of the Boc group within the β-cyclodextrin cavity (106 visite)
Impellizzeri G, Pappalardo G, D'Alessandro F, Rizzarelli E, Saviano M, Iacovino R, Benedetti E, Pedone C
European J Org Chem (ISSN: 1434-193x), 2000; (6): 1065-1076.
Impact Factor: 2.15
Dettagli    Esporta in BibTeX    Esporta in EndNote

Co-ordinating properties of cyclopeptides. Thermodynamic and spectroscopic study on the formation of copper(II) complexes with cyclo(Gly-His)4 and cyclo(Gly-His-Gly)2 and their superoxide dismutase-like activity (163 visite)
Bonomo RP, Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E, Tabbì G
N/D (ISSN: 0300-9246), 1998; (22): 3851-3857.
Impact Factor: 2.507
Dettagli    Esporta in BibTeX    Esporta in EndNote

Synthesis, spectroscopic characterisation, and metal ion interaction of a new α-helical peptide (123 visite)
Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E, Santoro AM
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1998; 4(9): 1791-1798.
Impact Factor: 5.153
Dettagli    Esporta in BibTeX    Esporta in EndNote

Antioxidant effect of copper(II) on photosensitized lipid peroxidation (100 visite)
Costanzo LL, De Guidi G, Giuffrida S, Sortino S, Condorelli G, Pappalardo G
J Chem Res (ISSN: 0162-0134print, 0162-0134linking, 1873-3344), 1995 Feb; 57(2): 115-125.
Impact Factor: 1.342
Dettagli    Esporta in BibTeX    Esporta in EndNote

A new water soluble host compound possessing two different hydrophobic recognition cavities: Calix[4]arene derivative conjugated with monofunctionalized β-cyclodextrin (130 visite)
DALESSANDRO F, GULINO F, IMPELLIZZERI G, PAPPALARDO G, RIZZARELLI E, SCIOTTO D, VECCHIO G
Tetrahedron Lett (ISSN: 0040-4039), 1994 Jan 24; 35(4): 629-632.
Impact Factor: 2.5
Dettagli    Esporta in BibTeX    Esporta in EndNote

Thermodynamic and Spectroscopic Characterization, and in vitro O2- Scavenger Activity of Copper(II) Complexes with Glycyl-L-histidyl-glycyl-L-histidine (103 visite)
Bonomo RP, Bonsignore F, Conte E, Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E
J Chem Soc (ISSN: 1364-5447), 1993; 8: 1295-1300.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Thermodynamic and 1H-NMR Study of Proton Complex Formation of Histidine-Containing Cyclodipeptides in Aqueous Solution (119 visite)
Arena G, Impellizzeri G, Maccarrone G, Pappalardo G, Sciotto D, Rizzarelli E
J Chem Soc, 1992; N/D: 371-376.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cyclopeptide Functionalized beta-Cyclodextrin. A New Class of Potentially Enzyme Mimicking Compound with Two Recognition Sites (107 visite)
Cucinotta V, D'Alessandro F, Impellizzeri G, Pappalardo G, Rizzarelli E, Vecchio G
Chem Commun, 1991; N/D: 293-294.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Non-Covalent Interactions in Cyclopeptide Proton Complex Formation in Aqueous Solution (88 visite)
Arena G, Impellizzeri G, Maccarrone G, Pappalardo G, Sciotto D, Rizzarelli E
Thermochim Acta, 1989; 154: 97-106.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote



100 Records (79 escludendo Abstract e Conferenze).
Impact factor totale: 309.323 (276.699 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 336.637 (284.994 escludendo Abstract e Conferenze).








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