View contact record, Full name: Giovanni Nicola Roviello
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NomeGiovanni Nicola Roviello
AreaRicerca e Sviluppo
QualificaRicercatore
SedeNapoli-Mezzocannone
IndirizzoVia Mezzocannone 16, 80134 Napoli - Italia
E-mailgiroviel@unina.it
Telefono ufficio+39 0812534585; +39 0812203415
▼    Malattie Neoplastiche
▼    Gadd45 beta and its implication in chronic inflammation
▼    Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions
▼    Characterization of the KCTD protein family: key factors in several biological processes
▼    Characterization of neurotoxic and neuroprotective factors by using computational methodologies
▼    Monoclonal Antibodies for therapeutic and diagnostic applications
▼    Targeted Drug Delivery by integrin avb3 antagonist
▼    Protein aggregation and cytotoxicity: molecular, in vitro and in vivo biological studies
Nessun risultato.
▼    Metals role in angiogenesis
Nessun risultato.
▼    Drug Delivery
Nessun risultato.
▼    Bioactive peptide-membrane assemblies
Nessun risultato.
▼    Metals and small molecules in the regulation of the Ubiquitin Proteasome Pathway
Nessun risultato.
▼    Protein semi-synthesis for biophysical and chemical biology applications
▼    Peptide modulators of the VEGF-dependent angiogenesis
▼    Peptides promoting reverse cholesterol transport
▼    CA IX as target for the development of new anti-tumour drugs
▼    Carbonic Anhydrase family as target for rational drug design
▼    Clinical Oncology
▼    Translational Molecular Imaging in Cancer
▼    Molecular imaging for personalized therapy in oncology
▼    Modeling radiation induced normal tissue effects
▼    Test e validazione di nuove sonde molecolari mediante imaging preclinico.
▼    Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Nucleic acid and protein binding studies
▼    Segmentazione cerebrale per applicazioni in radiologia oncologica
▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
▼    Tecnologie e tecniche in medicina
▼    Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Nucleic acid and protein binding studies
▼    Altre Malattie
▼    Production and characterization of recombinant enzymes for biochemical and biotechnological applications
▼    Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions
▼    Characterization of neurotoxic and neuroprotective factors by using computational methodologies
▼    Protein aggregation and cytotoxicity: molecular, in vitro and in vivo biological studies
Nessun risultato.
▼    Metals role in angiogenesis
Nessun risultato.
▼    Drug Delivery
Nessun risultato.
▼    Bioactive peptide-membrane assemblies
Nessun risultato.
▼    Protein semi-synthesis for biophysical and chemical biology applications
▼    Peptide modulators of the VEGF-dependent angiogenesis
▼    Peptides promoting reverse cholesterol transport
▼    Comparison of noninvasive cardiac imaging modalities in patients with myocardial infarction
▼    Structural and functional studies of virulence factors in Mycobacterium tuberculosis infection
▼    Assessment of the cardiac risk and its temporal variation
▼    Carbonic Anhydrase family as target for rational drug design
▼    Test e validazione di nuove sonde molecolari mediante imaging preclinico.
▼    Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Nucleic acid and protein binding studies
▼    Fenotipizzazione di modelli murini mediante imaging preclinico.
▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
▼    Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Nucleic acid and protein binding studies


 

E-mails: giroviel@unina.it; giovanni.roviello@cnr.it;

H-index: 17(Scopus)

ORCID ID: https://orcid.org/0000-0001-6065-2367

https://www.scopus.com/authid/detail.uri?authorId=35580154100
https://www.reviewercredits.com/user/giovrovi/

 

June 2002: Degree in Chemistry cum laude. Federico II University, Naples – Italy

 

June 2002-Jan. 2003: partecipation in the European Research Project Centre for Design and Structure in Biology (CDSB) -Jena (Germany), Istituto di Biostrutture e Bioimmagini del CNR, Napoli/IMB-Institut fr Molekulare Biotechnologie, Jena (Germany).

 

November 2002-January 2006: Ph. D. in Biotechnology Federico II University, Naples - Italy. Thesis: PNA/DNA chimeras for biotechnological applications.

 

March 2005-June 2005: Research activity at the Georg-August-Universität of Goettingen (Germany).

 

April 2006-May 2006: scientific collaboration with RiboVax Biotechnologies S. A.

 

June 2006-November 2006: scientific collaboration with Biostructure and Bioimaging Institute of National Council of Research (IBB-CNR).

 

November 2006-today: CNR Researcher at Biostructure and Bioimaging Institute of National Council of Research.

 

 1st April 2017 -31st May 2017: visiting researcher at UCD-Dublin /O'Brien Science Centre and collaboration with Kelada Pharmachem Ltd (H2020 Marie Sklowdowska-Curie RISE grant - ChemoEnz).

 

1st September 2018 -30 November 2018: supervisor of  Dr. Marta Fik (post-doc activity at IBB-CNR, SONATINA 1 Research Programme no. 2017/24/C/ST5/00181) and Martyna Szymanska (doctorate activity at IBB-CNR, CHEMINTER Research Programme no. POWR.03.02.00-00-IO26/16), both from Department of Bioinorganic Chemistry, Faculty of Chemistry - Adam Mickiewicz University in Poznan, POLAND. 

 

IBB CNR Research Coordinator for the scientific collaborations with Adam Mickiewicz University - Poznan, POLAND, (Agreement prot n. IBB CNR 0001777 26/09/2018)

 

7th January 2019 -28th January 2019: visiting researcher at Friedrich-Alexander University - Erlangen, Germany and collaboration with prof. Andriy Mokhir (Department Chemie und Pharmazie). CNR Short Term Mobility programme (STM 2018 prot.n. CNR0067802/2018 - 15/10/2018)

 


Teaching activities:

September 2004-September 2006: Lecturer at Chemistry introductive course, Faculty of Sciences Federico II University of Naples.

November 2007-November 2010 and May 2012 - November 2012: Lecturer in Chemistry, Federico II University of Naples.(Facoltà di Biotecnologie; Facoltà di Agraria; Chimica Generale ed Inorganica) 

November 2010-March 2012: Lecturer in Chemistry, Parthenope University of Naples. (Facoltà di Scienze e Tecnologie; Chimica Generale ed Inorganica con Laboratorio)

January 2019: Lecturer in Chemistry, Friedrich-Alexander University - Erlangen, Germany ('Bioanorganische Chemie III' CME3-B5, M.Sc. Chemistry WS 18/19)

 

Project Leaderships:

January 2012-2015: Project leader/coordinator of  the international research project “Nucleopeptides for biomedical strategies”; Joint research Project – CNR/SRNSF (Georgia) cooperation (CNR Prot. N. 0001165 del 10/01/2011);

Project leader of the project \"sintesi chimica di agenti chemiluminescenti\" (prot. IBB CNR N. 0001626 25/09/2012 ; prot. IBB CNR N. 0001024 30/04/2014) in collaboration with Altergon Italia S.r.l.

Project leader/coordinator of the research project “Nuovi sistemi nucleopeptidici per applicazioni diagnostiche”; Legge Regionale 5. Annualità 2007 - Regione Campania (funded research project started in November 2015)

 Editorial Board Member, Modern Issues of Medicine and Management, publisher: Geomedi University, Georgia, ISSN 1512-4169

Membership in scientific committees: 1- 3rd International Conference of Young Scientists – Chemistry Today - 2013, Georgia; 2- 4th International Conference of Young Scientists - Chemistry Today - 2014, Armenia; 3- Novel Strategies in Anticancer Therapy and Diagnostics - Workshop in the frame of the POR FESR 2014 - 2020 - 2019, Italy.


Other appointments:

 

May 2012: achievement of the title of Professor honoris causa in Medicinal Chemistry, Geomedi Medical University of Tbilisi - Georgia.

May 2012: Nomination as an Expert consultant in the field of Chemistry for Chemical, Biological, Radiological and Nuclear (CBRN) Centres of Excellence (CoE).

November 2012-September 2016 Supervisor for the General Chemistry Laboratory, Department of Biological Sciences, Parthenope University of Naples.

June 2012: Poster Prize awarded at COST Conference Personalised Medicine: Better Healthcare for the Future 17-22 Giugno 2012, Larnaca, Cipro

January 2014-July 2016: participant in the Caspases Project supported by Regione Sardegna



Italian National Scientific Qualification (Abilitazione Scientifica Nazionale): habilitation as "Associate Professor" (II fascia)

2017 - 03/C1 - Organic Chemistry

2017 - 03/B1 - Inorganic & General Chemistry

2017 - 05/E1 - General Biochemisty

 

Editorial Board Member, Modern Issues of Medicine and Management, publisher: Geomedi University, Georgia, ISSN 1512-4169


Membership in conference scientific committees: 


1- 3rd International Conference of Young Scientists – Chemistry Today - 2013, Georgia;

2- 4th International Conference of Young Scientists - Chemistry Today -  2014, Armenia;

3- Novel Strategies in Anticancer Therapy and Diagnostics - Workshop in the frame of the POR FESR 2014 - 2020  - 2019, Italy.

4- Towards Novel Anticancer Strategies: It’s Time to Build a New Research Community - Workshop in the frame of the POR FESR 2014 - 2020  - 2019, Italy.

https://sites.google.com/view/anti-cancer-strategy/home




Some conferences and achievements:

Aug 2011 EBSA bursary by European Biophysical Societies\' Association for the attendance to the \"8th EBSA European Biophysics Congress\" August 23rd–27th 2011, Budapest, Hungary, as reported in Eur Biophys J (2011) 40 (Suppl 1):S11

Oct 2011 CNR bursary – Individual Training Plan for the attendance to the \"ESF-COST High-Level Research Conference - Systems Chemistry III 23-28 October 2011 – Amoudara – Crete, Greece. (formazione individuale CNR Quota A; prot. N. 0009547 - 31/01/11).

 


Referee (Reviewer Credits - Reviewer Index 14):

Journal of Physical Chemistry - American Chemical Society, Bioconjugate Chemistry - American Chemical Society, Molecular Biology and Evolution - Oxford University Press, International Journal of Biological Macromolecules - Elsevier, New Journal of Chemistry - Royal Society of Chemistry,  Current Medicinal Chemistry, Bentham Science Publishers; Current Pharmaceutical Design, Bentham Science Publishers; Medicinal Chemistry, Bentham Science Publishers; International Journal of Nanomedicine, Dove Medical Press; International Journal of Pharmaceutics, Elsevier; Nucleosides, Nucleotides and Nucleic Acids, Taylor & Francis.

 



 Memberships:

EPS (European Peptide Society), member since 2008.

EFB (European Federation of Biotechnology), member since 2016

Reviewer Credits, member since  2017

 SCI (Società Chimica Italiana)

 

 

 

 


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Bibliografia
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* Thiophenyl-substituted triazolyl-thione L-alanine: asymmetric synthesis, aggregation and biological properties (282 visite)
Saghyan AS, Simonyan HM, Petrosyan SG, Geolchanyan AV, Roviello GN, Musumeci D, Roviello V
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2014 Oct; 46(10): 2325-2332.
Impact Factor: 3.293
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Thermodynamic studies on PNA and PNA/DNA dendrimer formation (119 visite)
Moccia M, Musumeci D, Valente M, Roviello GN, Sapio R, Pedone C, Bucci EM
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1173-1176.
Impact Factor: 0.723
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthetic approaches to nucleopeptides containing all the four nucleobases, and nucleic acid-binding studies on a mixed-sequence nucleo-oligolysine (215 visite)
Roviello GN, Musumeci D
Rsc Adv (ISSN: 2046-2069), 2016 Jun; 6: 63578-63585.
Impact Factor: 3.108
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis, structure and reactivity of amino-benzodifurane derivatives (190 visite)
Caruso U, Panunzi B, Roviello GN, Roviello GN, Tingoli M, Tuzi A
Comptes Rendus Chimie (ISSN: 1631-0748), 2009 May; 12(5): 622-634.
Impact Factor: 1.58
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (190 visite)
Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 May; 38(5): 1489-1496.
Impact Factor: 4.106
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis, self-assembly-behavior and biomolecular recognition properties of thyminyl dipeptides (221 visite) (PDF 4 visite)
Roviello GN, Oliviero G, Di Napoli A, Borbone N, Piccialli G
Arabian Journal Of Chemistry, 2020; 13: 1966-1974.
Impact Factor: 3.3
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis, DNA binding studies, and antiproliferative activity of novel Pt(II)- complexes with an L-alanyl-based ligand (38 visite)
Riccardi C, Capasso D, Rozza GM, Platella C, Montesarchio D, Di Gaetano S, Marzo T, Pratesi A, Messori L, Roviello GN, Musumeci D
J Inorg Biochem (ISSN: 0162-0134linking), 2019 Oct 21; 203: 110868-110868.
Impact Factor: 3.224
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (219 visite)
Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis, Characterization And Hybridization Studies Of An Alternate Nucleo-Epsilon/Gamma-Peptide: Complexes Formation With Natural Nucleic Acids (206 visite)
Roviello GN, Musumeci D, Pedone C, Bucci EM
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jan; 38(1): 103-111.
Impact Factor: 4.106
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis, biological evaluation and supramolecular assembly of novel analogues of peptidyl nucleosides (526 visite)
Roviello GN, Ricci A, Bucci EM, Pedone C
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1773-1778.
Impact Factor: 3.534
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (175 visite)
Roviello GN, Gröschel S, Pedone C, Diederichsen U
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2010 May; 38(5): 1301-1309.
Impact Factor: 4.106
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis of a thymine-functionalized nucleoamino acid for the solid phase assembly of cationic nucleopeptides (250 visite)
Roviello GN, Musumeci D, D'Alessandro C, Pedone C
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2013 Oct; 45(4): 779-784.
Impact Factor: 3.653
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (221 visite)
Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis of a novel benzodifuran derivative and its molecular recognition of poly rA RNA (193 visite)
Roviello GN, Roviello V, Musumeci D, Pedone C
Biol Chem Biological Chemistry (ISSN: 1437-4315, 1431-6730), 2013 Sep; 394(9): 1235-1239.
Impact Factor: 2.689
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* Synthesis of a l-lysine-based alternate alpha, epsilon-peptide: A novel linear polycation with nucleic acids-binding ability (219 visite)
Moccia M, Roviello GN, Bucci EM, Pedone C, Saviano M
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2010 Sep 15; 397(1-2): 179-183.
Impact Factor: 3.607
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (222 visite)
Roviello GN, Musumeci D, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis and supramolecular assembly of 1, 3-bis(1 '-uracilyl)-2-propanone (200 visite)
Roviello GN, Roviello GN, Musumeci D, Capasso D, Di Gaetano S, Costanzo M, Pedone C
Rsc Adv (ISSN: 2046-2069), 2014; 4(54): 28691-28698.
Impact Factor: 3.84
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* Synthesis and Enantiomeric Separation of a Novel Spiroketal derivative: A Potent Human Telomerase Inhibitor with High In Vitro Anticancer Activity (181 visite)
Fuggetta MP, De Mico A, Cottarelli A, Morelli F, Zonfrillo M, Ulgheri F, Peluso P, Mannu A, Deligia F, Marchetti M, Roviello GN, Romero AR, Dömling A, Spanu P
Journal Of Medicinal Chemistry, 2016 Mar; 59: 9140-9149.
Impact Factor: 5.589
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis and characterization of a novel ester-based nucleoamino acid for the assembly of aromatic nucleopeptides for biomedical applications (284 visite)
Roviello GN, Musumeci D, Bucci EM, Pedone C
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2011 Sep 30; 415(1-2): 206-210.
Impact Factor: 3.35
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis and biological evaluation of a novel Amadori compound (153 visite)
Roviello GN, Iannitti R, Roviello V, Palumbo R, Simonyan H, Vicidomini C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2017 Nov; 49(2): 327-335.
Impact Factor: 2.906
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthesis and aggregation properties of a novel enzymatically resistant nucleoamino acid (223 visite)
Roviello GN, Mottola A, Musumeci D, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Oct; 43(4): 1465-1470.
Impact Factor: 3.914
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo (197 visite)
Romanò MF, Van De Weerd R, Brouwer FCC, Roviello GN, Lacroix R, Sparrius M, Van Den Brink-van Stempvoort G, Maaskant JJ, Van Der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R
Structure (ISSN: 0969-2126, 1878-4186), 2014 May 6; 22(5): 719-730.
Impact Factor: 5.618
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Spectroscopic and SEM evidences for G4-DNA binding by a synthetic alkyne-containing amino acid with anticancer activity (44 visite) (PDF 8 visite)
Fik-jaskółka MA, Mkrtchyan AF, Saghyan AS, Palumbo R, Belter A, Hayriyan LA, Simonyan H, Roviello V, Roviello GN
Spectrochimica Acta Part A, 2019 Dec 03; N/D: N/D-N/D.
Impact Factor: 2.931
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Solid phase synthesis of TyrT, a thymine-tyrosine conjugate with poly(A) RNA-binding ability (327 visite)
Roviello GN, Roviello V, Autiero I, Saviano M
Rsc Adv (ISSN: 2046-2069), 2016; 6(33): 27607-27613.
Impact Factor: 3.108
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Solid phase synthesis of a novel folate-conjugated 5-aminolevulinic acid methyl ester based photosensitizer for selective photodynamic therapy (222 visite)
Guaragna A, Roviello GN, D'Errico S, Paolella C, Palumbo G, D'Alonzo D
Tetrahedron Lett (ISSN: 0040-4039), 2015 Feb 4; 56(6): 775-778.
Impact Factor: 2.347
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* Solid Phase Synthesis And Rna-Binding Studies Of A Serum-Resistant Nucleo-Epsilon-Peptide (187 visite)
Roviello GN, Musumeci D, Castiglione M, Bucci EM, Pedone C, Benedetti E
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 155-160.
Impact Factor: 1.807
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide (200 visite)
Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
Rsc Adv (ISSN: 2046-2069), 2016; 6(17): 14140-14148.
Impact Factor: 3.108
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry (245 visite)
Troise AD, Fiore A, Roviello GN, Monti SM, Fogliano V
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015 Jan; 47(1): 111-124.
Impact Factor: 3.196
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: a biophysical, computational and biological approach (65 visite)
Platella C, Raucci U, Rega N, D’atri S, Levati L, Roviello GN, Fuggetta MP, Musumeci D, Montesarchio D
International Journal Of Biological Macromolecules, 2019 Dec 31; N/D: N/D-N/D.
Impact Factor: 4.784
Dettagli    Esporta in BibTeX    Esporta in EndNote

* RNA-binding and viral reverse transcriptase inhibitory activity of a novel cationic diamino acid-based peptide (174 visite)
Roviello GN, Di Gaetano S, Capasso D, Franco S, Crescenzo C, Bucci EM, Pedone C
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2011 Apr 14; 54(7): 2095-2101.
Impact Factor: 5.248
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* Recent Advances in Nuclear Imaging of Receptor Expression to Guide Targeted Therapies in Breast Cancer (60 visite) (PDF 27 visite)
Salvatore B, Caprio MG, Hill BS, Sarnella A, Roviello GN, Zannetti A
Cancers (ISSN: 2072-6694linking), 2019 Oct 22; 11(10): N/D-N/D.
Impact Factor: 6.162
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks (281 visite)
Moccia M, Musumeci D, Roviello GN, Fusco S, Valente M, Bucci EM, Sapio R, Pedonea C, Netti PA
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Oct; 15(10): 647-653.
Impact Factor: 1.807
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* ODN-based drugs for targeting of extracellular proteins (145 visite)
Bucci EM, Valente M, Musumeci D, Sapio R, Anrò V, Roviello GN, Moccia M
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1047-1050.
Impact Factor: 0.723
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Nucleobase-containing peptides: An overview of their characteristic features and applications (284 visite)
Roviello GN, Benedetti E, Pedone C, Bucci EM
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jun; 39(1): 45-57.
Impact Factor: 4.106
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Nucleobase-containing peptides: a spectroscopic study of their properties and nucleic acids recognition ability (215 visite)
Roviello GN, Musumeci D, Bucci EM, Pedone C
Eur Biophys J (ISSN: 0175-7571, 1432-1017), 2011 Sep; 40: N/D-N/D.
Impact Factor: 2.139
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* Nucleic acid binding and other biomedical properties of artificial oligolysines (133 visite)
Roviello GN, Vicidomini C, Costanzo V, Roviello V
International Journal Of Nanomedicine, 2016 Nov; 11: 5897-5904.
Impact Factor: 4.32
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* Novel insights into nucleoamino acids: biomolecular recognition and aggregation studies of a thymine-conjugated L-phenyl alanine (191 visite)
Roviello GN
Amino Acids (ISSN: 1438-2199electronic, 0939-4451linking), 2018 May 15; DOI10.1007/s00726-01: 933-941.
Impact Factor: 3.173
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* New G-quadruplex-forming oligodeoxynucleotides incorporating a bifunctional Double-Ended Linker (DEL): effects of DEL size and ODNs orientation on the topology, stability and molecularity of DEL-G-quadruplexes (87 visite)
Marzano M, Falanga AP, D'Errico S, Pinto B, Roviello GN, Piccialli G, Oliviero G, Borbone N
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2019 Feb 12; 24(3): 654-654.
Impact Factor: 3.06
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* New artificial biomimetic enzyme analogues based on iron(II/III) Schiff Base complexes: an effect of (benz)imidazole organic moieties on phenoxazinone synthase and DNA recognition (47 visite)
Bocian A, Szymańska M, Brykczyńska D, Kubicki M, Wałęsa-chorab M, Roviello GN, Fik-jaskółka MA, Gorczyński A, Patroniak V
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2019 Aug 31; 24(17): 3173-3173.
Impact Factor: 3.06
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* Natural and artificial binders of polyriboadenylic acid and their effect on RNA structure (187 visite)
Roviello GN, Musumeci D, Roviello V, Pirtskhalava M, Egoyan A, Mirtskhulava M
Beilstein J Nanotech (ISSN: 2190-4286), 2015; 6(1): 1338-1347.
Impact Factor: 2.778
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* Lac-L-TTA, a novel lactose-based amino acid-sugar conjugate for anti-metastatic applications (127 visite)
Roviello GN, Iannitti R, Palumbo R, Simonyan H, Vicidomini C, Roviello V
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2017 May 06; 49(8): 1347-1353.
Impact Factor: 2.906
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* In vivo imaging and characterization of [(18)F]DPA-714, a potential new TSPO ligand, in mouse brain and peripheral tissues using small-animal PET (329 visite) (PDF 192 visite)
Vicidomini C, Panico M, Greco A, Gargiulo S, Coda ARD, Zannetti A, Gramanzini M, Roviello GN, Quarantelli M, Alfano B, Tavitian B, Dolle F, Salvatore M, Brunetti A, Pappata S
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 2015 Mar; 42(3): 309-316.
Impact Factor: 2.429
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* Hairpin ODN-based ligands as potential inhibitors of HMGB1 cytokine activity (252 visite)
Musumeci D, Roviello GN, Montesarchio D, Sapio R, Valente M, Anr V, Bucci EM
Rsc Adv (ISSN: 2046-2069), 2013; 3(30): 12176-12184.
Impact Factor: 3.708
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* G-quadruplex-forming oligonucleotide conjugated to magnetic nanoparticles: Synthesis, characterization, and enzymatic stability assays (217 visite)
Musumeci D, Oliviero G, Roviello GN, Bucci EM, Piccialli G
Bioconjug Chem (ISSN: 1043-1802, 1520-4812, 1520-4812electronic), 2012 Mar 21; 23(3): 382-391.
Impact Factor: 4.58
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* G-quadruplex-based aptamers against protein targets in therapy and diagnostics (118 visite)
Platella C, Riccardi C, Montesarchio D, Roviello GN, Musumeci D
Bba-Gen Subjects (ISSN: 0304-4165, 0006-3002, 1872-8006electronic), 2017 May; 1861(5PtB): 1429-1447.
Impact Factor: 3.679
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* Evidences Of Complex Formation Between Daba-Based Nucleo-Gamma-Peptides With Alternate Configuration Backbone (220 visite)
Roviello GN, Musumeci D, Moccia M, Castiglione M, Cesarani A, Bucci EM, Saviano M, Pedone C, Benedetti E
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 147-154.
Impact Factor: 1.807
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Evidences for supramolecular organization of nucleopeptides: Synthesis, spectroscopic and biological studies of a novel dithymine l-serine tetrapeptide (222 visite)
Roviello GN, Musumeci D, Bucci EM, Pedone C
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 Apr; 7(4): 1073-1080.
Impact Factor: 3.534
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Evidences for complex formation between l-dabPNA and aegPNA (162 visite)
Roviello GN, Musumeci D, Bucci EM, Castiglione M, Cesarani A, Pedone C, Piccialli G
Bioorg Med Chem Lett (ISSN: 0960-894x, 1464-3405, 1464-3405electronic), 2008 Sep 1; 18(17): 4757-4760.
Impact Factor: 2.531
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* Evaluation of an Analogue of the Marine epsilon-PLL Peptide as a Ligand of G-quadruplex DNA Structures (10 visite) (PDF 3 visite)
Marzano M, Falanga AP, Marasco D, Borbone N, D'Errico S, Piccialli G, Roviello GN, Oliviero G
Mar Drugs (ISSN: 1660-3397linking), 2020 Jan 11; 18(1): N/D-N/D.
Impact Factor: 3.772
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* Evaluating the biological properties of synthetic 4-nitrophenyl functionalized benzofuran derivatives with telomeric DNA binding and antiproliferative activities (138 visite)
Carella A, Roviello V, Iannitti R, Palumbo R, La Manna S, Marasco D, Trifuoggi M, Diana R, Roviello GN
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2019 Jan; 121: 77-88.
Impact Factor: 4.784
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* Erratum: Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (Amino Acids DOI: 10. 1007/s00726-009-0324-x) (164 visite)
Roviello GN, Gröschel S, Pedone C, Diederichsen U
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010; 38(5): 1311-1312.
Impact Factor: 4.106
Dettagli    Esporta in BibTeX    Esporta in EndNote

* DNA-based strategies for blocking HMGB1 cytokine activity: Design, synthesis and preliminary in vitro/in vivo assays of DNA and DNA-like duplexes (205 visite)
Musumeci D, Bucci EM, Roviello GN, Sapio R, Valente M, Moccia M, Bianchi ME, Pedone C
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1742-1752.
Impact Factor: 3.534
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* DNA- and RNA-binding ability of oligoDapT, a nucleobase-decorated peptide, for biomedical applications (270 visite)
Musumeci D, Roviello V, Roviello GN
Int J Nanomed (ISSN: 1176-9114linking, 1178-2013electronic), 2018 May 1; 2018:13: 2613-2629.
Impact Factor: 4.3
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* Dipentyl 2, 6-diaminobenzo[1, 2-b: 4, 5-b']difuran-3, 7-dicarboxylate (177 visite)
Roviello G, Borbone F, Carella A, Roviello GN, Tuzi A
Acta Crystallographica Section E Structure Reports Online (ISSN: 1600-5368, 1600-5368electronic), 2013 Sep 12; 69(Pt10): o1526-o1526.
Impact Factor: 2.069
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* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (189 visite)
Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
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* Dabpna: Design, Synthesis And Nucleic Acids Binding Studies (205 visite)
Roviello GN, Musumeci D, Moccia M, Castiglione M, Sapio R, Valente M, Bucci EM, Perretta G, Pedone C
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(10-12): 1307-1310.
Impact Factor: 0.723
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* Cationic peptides as RNA compaction agents: A study on the polyA compaction activity of a linear alpha, epsilon-oligo-l-lysine (270 visite)
Roviello GN, Musumeci D, Roviello V
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2015; 485(1-2): 244-248.
Impact Factor: 3.994
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* Binding ability of a thymine-functionalized oligolysine towards nucleic acids (163 visite)
Roviello GN, Musumeci D, D'Alessandro C, Pedone C
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391), 2014 Feb 1; 22(3): 997-1002.
Impact Factor: 2.793
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* Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound (243 visite)
Vicidomini C, Cioffi F, Broersen K, Roviello V, Riccardi C, Montesarchio D, Capasso D, Gaetano SD, Musumeci D, Roviello GN
Future Med Chem (ISSN: 1756-8919linking, 1756-8927electronic), 2019 Feb 25; 10.4155/fmc-2018-047: N/D-N/D.
Impact Factor: 3.617
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* Benzodifuran derivatives as potential antiproliferative agents: possible correlation between the bioactivity and their aggregation properties (266 visite)
Musumeci D, Roviello GN, Rigione G, Capasso D, Di Gaetano S, Riccardi C, Roviello V, Montesarchio D
Chempluschem, 2017; 82: 251-260.
Impact Factor: 2.8
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* Bent oligonucleotide duplexes as HMGB1 inhibitors: A comparative study (205 visite)
Musumeci D, Roviello GN, Moccia M, Pedone C, Bucci EM, Sapio R, Valente M, Fumero S
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(10-12): 1447-1450.
Impact Factor: 0.723
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* Antitumour activity of resveratrol on human melanoma cells: a possible mechanism related to its interaction with malignant cell telomerase (131 visite)
Platella C, Guida S, Bonmassar L, Aquino A, Bonmassar E, Ravagnan G, Montesarchio D, Roviello GN, Musumeci D, Fuggetta MP
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print), 2017 Aug 02; 1861(11PtA): 2843-2851.
Impact Factor: 4.28
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* An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies (219 visite)
Musumeci D, Roviello GN, Montesarchio D
Pharmacol Therapeut (ISSN: 0163-7258), 2014 Mar; 141(3): 347-357.
Impact Factor: 9.723
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* Alternate dab-aegPNAs: synthesis, nucleic acid binding studies and biological activity (211 visite)
Roviello GN, Musumeci D, De Cristofaro A, Capasso D, Di Gaetano S, Bucci EM, Pedone C
Mol Biosyst (ISSN: 1742-2051, 1742-206x, 1742-2051electronic), 2010 Jan; 6(1): 199-205.
Impact Factor: 3.825
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* A COMPUTER MODELING STUDY OF BINDING PROPERTIES OF CHIRAL NUCLEOPEPTIDE FOR BIOMEDICAL APPLICATIONS (165 visite)
Pirtskhalava M, Egoyan A, Mirtskhulava M, Roviello GN
Georgian Med News (ISSN: 1512-0112print, 1512-0112linking), 2017 Dec; (273): 1123-1128.
Impact Factor: 0
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65 Records (62 escludendo Abstract e Conferenze).
Impact factor totale: 218.055 (210.168 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 201.468 (177.108 escludendo Abstract e Conferenze).








Ultima modifica di Giovanni Nicola Roviello in data Tuesday 21 January 2020, 12:44:47
2856 visite. Ultima visita in data Tuesday 28 January 2020, 10:16:56