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NomeRita Berisio
AreaRicerca e Sviluppo
QualificaPrimo Ricercatore
SedeNapoli - Mezzocannone
IndirizzoVia Mezzocannone 16, 80134 Napoli - Italia
E-mailrita.berisiounina.it
Telefono ufficio+39 081 2534507
Cellulare+39 349.441.50.22

Rita Berisio was born in 1972 in Naples, Italy. In 1995, she graduated in chemistry at the University of Naples Federico II (summa cum laude). From 1996 to 1998 she worked at the European Molecular Biology Lab in Hamburg and in 1999 she received her PhD at the University of Naples. 

Since 2001, Rita Berisio is a permanent researcher at the Institute of Biostructures and Bioimaging (IBB) of the Italian Research National Council (CNR), in Naples, Italy. In 2002-2004 she joined the group of Prof. Ada Yonath, Chemistry Nobel Prize in 2009, at the Max-Planck-Institute in Hamburg, Germany. Rita Berisio has been awarded the prize of the Italian Crystallography Association (AIC) in 2006 for her contribution to structural biology.

Since 2002, Rita Berisio is Senior Researcher at the Institute of Biostructures and Bioimaging (IBB) of the Italian Research National Council (CNR), in Naples, Italy. Dr Berisio is co-author of more than 110 publications on international journals (among which Nat Struct Biol, Mol Cell, JACS, PNAS, Structure), book chapters, and one patent.

She has been Guest Editor of a number of journals and is member of the Editorial Board of The Scientific World Journal. 

Dr. Berisio is Editorial Advisory Board Member of "Current Medicinal Chemistry".

She has been responsible for Regional, National and International funding initiatives, eg:

(i) Italian Ministry of Research, project PON03PE_00157. Role: PI, 2014-2017, Title: “Smart Generation”

(ii) Indigo Linking programme Italy-India-UK, funded by EU. Role: International Coordinator, 2015-2017. Title: “DRAT- Drugs against Tuberculosis”

(iii) COST Action (European Cooperation in the field of Scientific and Technical Research) BM1003. Role: PI, 2010-2014  and Grant Holder 2010-2012. Title: “Microbial cell surface determinants of virulence as targets for new therapeutics in Cystic Fibrosis”

(iv) Mizutani Foundation for Glycoscience. Role: International Coordinator, 2011-2012. Title: “Molecular mechanisms of defense response induced by chitin oligosaccharides”

(v) Italian Research Council, Cooperation projects with Poland (PI, 2014-2016); with Japan, (PI, 2016-2017).

(vi) Italian Ministry of Research. Role: PI, 2011-2012. Title: “Structural studies of key proteins in the pathogenesis of M. tuberculosis”

Research interests

1.    Elucidating the structure and in vitro function of key proteins involved in human pathogenesis

2.    Determining key regulatory mechanisms of cell wall modelling in pathogenic bacteria by coupling x-ray crystallography and biophysical techniques with computational methods and biochemical assays

3.    Elucidating structural and functional features of protein mediators of host:pathogen interactions 

4.    Study of molecular biomarkers of tumor and respiratory pathogeneses


Contiene: [X]      Estesa         Autori: [X]      Tipo di lavoro: [X]
Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
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* Domain communication in Thermotoga maritima Arginine Binding Protein unraveled through protein dissection (14 visite)
Smaldone G, Balasco N, Vigorita M, Ruggiero A, Cozzolino S, Berisio R, Del Vecchio P, Graziano G, Vitagliano L
Int J Biol Macromol (ISSN: 0141-8130linking), 2018 Nov; 119: 758-769.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Phage-Borne Depolymerases Decrease Klebsiella pneumoniae Resistance to Innate Defense Mechanisms (4 visite)
Majkowska-skrobek G, Latka A, Berisio R, Squeglia F, Maciejewska B, Briers Y, Drulis-kawa Z
Front Microbiol (ISSN: 1664-302xprint, 1664-302xlinking), 2018 Oct 23; 9: 2517-2517.
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* Collagen degradation in tuberculosis pathogenesis: the biochemical consequences of hosting an undesired guest (27 visite)
Squeglia F, Ruggiero A, Berisio R
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2018 Oct 11; 475(19): 3123-3140.
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* PASTA sequence composition is a predictive tool for protein class identification (15 visite)
Calvanese L, Falcigno L, Squeglia F, Berisio R, D'Auria G
Amino Acids (ISSN: 1438-2199electronic, 0939-4451linking), 2018 Oct; 50(10): 1441-1450.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural and enzymatic properties of Ageritin, a novel metal-dependent ribotoxin-like protein with antitumor activity (22 visite)
Ruggiero A, Garcia-ortega L, Ragucci S, Russo R, Landi N, Berisio R, Di Maro A
Biochim Biophys Acta Gen Subj (ISSN: 1872-8006electronic, 0304-4165linking), 2018 Sep 18; 1862(12): 2888-2894.
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* Streptococcal Collagen-like Protein 1 Binds Wound Fibronectin: Implications in Pathogen Targeting (20 visite)
Mcnitt DH, De Water LV, Marasco D, Berisio R, Lukomski S
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2018 Aug 31; N/D: N/D-N/D.
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* Domain swapping dissection in Thermotoga maritima arginine binding protein: How structural flexibility may compensate destabilization (11 visite)
Smaldone G, Berisio R, Balasco N, D'Auria S, Vitagliano L, Ruggiero A
Biochim Biophys Acta Proteins Proteom (ISSN: 1570-9639print, 1570-9639linking), 2018 May 31; 1866(9): 952-962.
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* The novel thermostable cellulose-degrading enzyme DtCel5H from Dictyoglomus thermophilum: crystallization and X-ray crystallographic analysis (53 visite)
Squeglia F, Berisio R, Ruggiero A
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xelectronic, 2053-230xlinking), 2018 Jan 1; 74(Pt1): 1-5.
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* A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics (67 visite)
Squeglia F, Ruggiero A, De Simone A, Berisio R
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018; 27: 369-380.
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* Chemistry of Peptidoglycan in Mycobacterium tuberculosis life style: an off-the-wall balance of synthesis and degradation (147 visite) (PDF 110 visite)
Squeglia F, Ruggiero A, Berisio R
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018; 24: 2533-2546.
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* Surface-exposed loops and an acidic patch in the Scl1 protein of group A Streptococcus enable Scl1 binding to wound-associated fibronectin (59 visite)
Mcnitt DH, Choi SJ, Keene DR, Van De Water L, Squeglia F, Berisio R, Lukomski S
J Biol Chem, 2018; N/D: N/D-N/D.
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* Defense Against Pathogens: Structural Insights into the Mechanism of Chitin Induced Activation of Innate Immunity (110 visite)
Squeglia F, Berisio R, Shibuya N, Kaku H
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2017 Nov 24; 24(36): 3980-3986.
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* Molecular Scenarios Behind Infectious Diseases (77 visite)
Berisio R, Squeglia F, Ruggiero A
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2017 Nov 24; 24(36): 3939-3941.
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* PASTA in Penicillin Binding Proteins and Serine/Threonine Kinases: A Recipe of Structural, Dynamic and Binding Properties (59 visite)
Calvanese L, Falcigno L, Squeglia F, D'Auria G, Berisio R
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2017 Nov 24; 24(36): 4038-4056.
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* Structural Versatility of Hepatitis C Virus Proteins: Implications for the Design of Novel Anti-HCV Intervention Strategies (72 visite)
Balasco N, Barone D, Sandomenico A, Ruggiero A, Doti N, Berisio R, Ruvo M, Vitagliano L
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2017 Nov 24; 24(36): 4081-4101.
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* Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis (84 visite)
Ruggiero A, Squeglia F, RomanoM, Vitagliano L, De Simone A, Berisio R
J Biomol Struct Dyn (ISSN: 1538-0254electronic, 0739-1102linking), 2017 May; 35(6): 1322-1330.
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* The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of inflammation (82 visite)
Dennehy R, RomanoM, Ruggiero A, Mohamed YF, Dignam SL, Mujica Troncoso C, Callaghan M, Valvano MA, Berisio R, Mcclean S
Cell Microbiol (ISSN: 1462-5822electronic, 1462-5814linking), 2017 May; 19(5): e12691-e12691.
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* Molecular players in Tuberculosis drug development: another break in the cell wall (103 visite)
Squeglia F, RomanoM, Ruggiero A, Berisio R
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2017 Feb 08; 24: 3954-3969.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Collagen-like proteins of pathogenic streptococci (84 visite)
Lukomski S, Bachert B, Squeglia F, Berisio R
Mol Microbiol (ISSN: 1365-2958electronic, 0950-382xlinking), 2017; 103: 919-930.
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* Molecular mechanisms of defense response induced by chitin oligosaccharides (57 visite)
Berisio R, Ruggiero A, Squeglia F, Esposito C, Molinaro A, Silipo A, Marchetti R, Shibuya N
Research Reports, 2017; N/D: N/D-N/D.
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* Structural and dynamic features of PASTA domains with different functional roles (106 visite)
Calvanese L, Falcigno L, Squeglia F, D'Auria G, Berisio R
Journal Of Biomolecular Structure & Dynamics, 2017; 35(10): 2293-2300.
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* Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy (95 visite)
Majkowska-skrobek G, Latka A, Berisio R, Maciejewska B, Squeglia F, RomanoM, Lavigne R, Struve C, Drulis-kawa Z
Viruses (ISSN: 1999-4915electronic, 1999-4915linking), 2016 Dec 1; 8(12): N/D-N/D.
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Unique Footprint in the scl1. 3 Locus Affects Adhesion and Biofilm Formation of the Invasive M3-Type Group A Streptococcus (106 visite)
Bachert BA, Choi SJ, Lasala PR, Harper TI, Mcnitt DH, Boehm DT, Caswell CC, Ciborowski P, Keene DR, Flores AR, Musser JM, Squeglia F, Marasco D, Berisio R, Lukomski S
Front Cell Infect Microbiol (ISSN: 2235-2988electronic, 2235-2988linking), 2016 Aug 31; 6: 90-90.
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* Identification of an OmpW homologue in Burkholderia pseudomallei, a protective vaccine antigen against melioidosis (76 visite)
Casey WT, Spink N, Cia F, Collins C, Romanò MF, Berisio R, Bancroft GJ, Mcclean S
Vaccine (ISSN: 1873-2518electronic, 0264-410xlinking), 2016 May 17; 34(23): 2616-2621.
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* Generation and characterization of monoclonal antibodies against a cyclic variant of Hepatitis C Virus E2 epitope 412-422 (130 visite) (PDF 93 visite)
Sandomenico A, Leonardi A, Berisio R, Sanguigno L, Foca G, Foca A, Ruggiero A, Doti N, Muscariello L, Barone D, Farina C, Owsianka A, Vitagliano L, Patel AH, Ruvo M
J Virol (ISSN: 1098-5514electronic, 0022-538xlinking), 2016 Jan 27; 90(7): 3745-3759.
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* Peptidoglycan-associated lipoprotein is a virulence factor that is involved in host cell attachment of Burkholderia cepacia complex (64 visite)
Dennehy R, RomanoM, Ruggiero A, Troncoso CM, Fathy Y, Callaghan M, Valvano M, Berisio R, Mcclean S
Cellular Microbiology, 2016; inpress: N/D-N/D.
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* Use of hydrolytic enzymes for algal biomass treatment (115 visite)
Ruggiero A, Squeglia F, Romano M, Berisio R
Current Biotechnology, 2016; 5: 296-304.
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* NMR Structure and Dynamics of the Resuscitation Promoting Factor RpfC Catalytic Domain (120 visite)
Maione V, Ruggiero A, Russo L, De Simone A, Pedone PV, Malgieri G, Berisio R, Isernia C
Plos One (ISSN: 1932-6203electronic, 1932-6203linking), 2015 Nov 17; 10(11): e0142807-e0142807.
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* A Unique Set of the Burkholderia Collagen-Like Proteins Provides Insight into Pathogenesis, Genome Evolution and Niche Adaptation, and Infection Detection (124 visite)
Bachert BA, Choi SJ, Snyder AK, Rio RV, Durney BC, Holland LA, Amemiya K, Welkos SL, Bozue JA, Cote CK, Berisio R, Lukomski S
Plos One (ISSN: 1932-6203electronic, 1932-6203linking), 2015 Sep 10; 10(9): e0137578-e0137578.
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* Structure and Function of RNase AS, a Novel Virulence Factor from Mycobacterium Tuberculosis (111 visite)
Romanò MF, Squeglia F, Berisio R
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2015 Apr 17; 22(14): 1745-1756.
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* A product of RpfB and RipA joint enzymatic action promotes the resuscitation of dormant mycobacteria (127 visite)
Nikitushkin VD, Demina GR, Shleeva MO, Guryanova SV, Ruggiero A, Berisio R, Kaprelyants AS
Febs J (ISSN: 1742-4658electronic, 1742-464xlinking), 2015 Apr 3; 282(13): 2500-2511.
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* Antimicrobial peptides as an opportunity against bacterial diseases (239 visite)
Galdiero S, Falanga A, Berisio R, Grieco P, Morelli G, Galdiero M
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2015 Mar 11; 22(14): 1665-1677.
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* Exit from mycobacterial dormancy: a structural perspective (139 visite)
Squeglia F, Ruggiero A, Berisio R
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Feb 9; 22(14): 1698-1709.
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* Differential thermodynamic behaviours of the extra-cellular regions of two Ser/Thr PrkC kinases revealed by calorimetric studies (104 visite)
Berisio R, Squeglia F, Ruggiero A, Petraccone L, Stellato MI, Del Vecchio P
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2015 Feb 8; 1854(5): 402-409.
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* Chemistry of lipid a: At the heart of innate immunity (191 visite) (PDF 185 visite)
Molinaro A, Holst O, Lorenzo FD, Callaghan M, Nurisso A, D'Errico G, Zamyatina A, Peri F, Berisio R, Jerala R, Jiménez-Barbero J, Silipo A, Martín-Santamarí S
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Jan 7; 21(2): 500-519.
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* Editorial: Molecular determinants of bacterial diseases (108 visite)
Berisio R
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2015; 22(14): 1640-1641.
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* Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: Evidence for the l-to-d inversion of configuration of the catalytic cysteine (122 visite)
Squeglia F, Ruggiero A, Romanò MF, Vitagliano L, Berisio R
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2014 Sep; 70(9): 2295-2300.
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* Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis (127 visite)
Calvanese L, Falcigno L, Maglione C, Marasco D, Ruggiero A, Squeglia F, Berisio R, D'Auria G
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Jul; 101(7): 712-719.
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* A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima (118 visite)
Ruggiero A, Dattelbaum JD, Staiano M, Berisio R, D'Auria S, Vitagliano L
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2014 May 15; 9(5): e96560-e96560.
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* Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo (122 visite)
Romanò MF, Van De Weerd R, Brouwer FCC, Roviello GN, Lacroix R, Sparrius M, Van Den Brink-van Stempvoort G, Maaskant JJ, Van Der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R
Structurestructure (ISSN: 0969-2126, 1878-4186), 2014 May 6; 22(5): 719-730.
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* The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41 (95 visite)
Squeglia F, Bachert B, De Simone A, Lukomski S, Berisio R
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2014 Feb 21; 289(8): 5122-5133.
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* Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization (153 visite)
Hayafune M, Berisio R, Marchetti R, Silipo A, Kayama M, Desaki Y, Arima S, Squeglia F, Ruggiero A, Tokuyasu K, Molinaro A, Kaku H, Shibuya N
Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2014 Jan 21; 111(3): E404-E404.
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* Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides (142 visite)
Cantisani M, Falanga A, Incoronato N, Russo L, De Simone A, Morelli G, Berisio R, Galdiero M, Galdiero S
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2013 Nov 14; 56(21): 8366-8376.
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* Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2. 3, a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes (104 visite)
Squeglia F, Bachert B, Romanò MF, Lukomski S, Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Sep; 69(9): 1023-1025.
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* Structures of free and inhibited forms of the L, D-transpeptidase LdtMt1 from Mycobacterium tuberculosis (113 visite)
Correale S, Ruggiero A, Capparelli R, Pedone E, Berisio R
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Sep; 69(Pt9): 1697-1706.
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* Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses (104 visite)
Squeglia F, Romanò MF, Ruggiero A, Vitagliano L, De Simone A, Berisio R
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jun 4; 104(11): 2530-2539.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the l, d-transpeptidase LdtMt1 from Mycobacterium tuberculosis (117 visite)
Correale S, Ruggiero A, Pedone E, Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Mar 1; 69(3): 253-256.
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* Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis (92 visite)
Ruggiero A, Marchant J, Squeglia F, Makarov V, De Simone A, Berisio R
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic), 2013 Feb 1; 31(2): 195-205.
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* Interplay between peptide bond geometrical parameters in nonglobular structural contexts (126 visite)
Esposito L, Balasco N, De Simone A, Berisio R, Vitagliano L
Biomed Res Int (ISSN: 2314-6133, 2314-6141, 2314-6141electronic), 2013; 2013: N/D-N/D.
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* Bacterial cell division regulation by Ser/Thr kinases: A structural perspective (119 visite)
Ruggiero A, De Simone P, Smaldone G, Squeglia F, Berisio R
Curr Protein Pept Sci (ISSN: 1389-2037), 2012 Dec; 13(8): 756-766.
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* Learning from pathogens: Exploiting host-pathogen liaison for therapeutic development (120 visite)
Berisio R
Curr Protein Pept Sci (ISSN: 1389-2037), 2012 Dec; 13(8): 697-698.
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* Polyproline and triple helix motifs in Host-Pathogen recognition (282 visite)
Berisio R, Vitagliano L
Curr Protein Pept Sci (ISSN: 1389-2037), 2012 Dec; 13(8): 855-865.
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* Editorial: cell processes in bacterial diseases (105 visite)
Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1011-1012.
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* Structural and Dynamic properties of incomplete immunoglobulin-like fold domains (132 visite)
Berisio R, Ciccarelli L, Squeglia F, De Simone A, Vitagliano L
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1045-1053.
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* Enhanced crystallizability by protein engineering approaches: A general overview (1777 visite)
Ruggiero A, Smaldone G, Squeglia F, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2012 Jul; 19(7): 732-742.
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* Structural and enzymatic properties of an in vivo proteolytic form of PD-S2, type 1 ribosome-inactivating protein from seeds of Phytolacca dioica (102 visite)
Di Maro A, Berisio R, Ruggiero A, Tamburino R, Severino V, Zacchia E, Parente A
Biochem Biophys Res Commun (ISSN: 0006-291x), 2012 May 11; 421(3): 514-520.
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* Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination (114 visite)
Esposito C, Cantisani M, D'Auria G, Falcigno L, Pedone E, Galdiero S, Berisio R
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2012 Mar 23; 586(6): 659-667.
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* Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy (87 visite)
Squeglia F, Marchetti R, Ruggiero A, Lanzetta R, Marasco D, Dworkin J, Petoukhov M, Molinaro A, Berisio R, Silipo A
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2011 Dec 28; 133(51): 20676-20679.
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* Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (107 visite)
Ruggiero A, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS, Berisio R, D'Auria S, Vitagliano L
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Nov 1; 67(11): 1462-1465.
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* Heparin-binding hemagglutinin HBHA from Mycobacterium tuberculosis affects actin polymerisation (85 visite)
Esposito C, Marasco D, Delogu G, Pedone E, Berisio R
Biochem Biophys Res Commun (ISSN: 0006-291x), 2011 Jul 1; 410(2): 339-344.
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* Role of hydration in collagen recognition by bacterial adhesins (85 visite)
Vitagliano L, Berisio R, De Simone A
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2011 May 4; 100(9): 2253-2261.
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* X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus (123 visite)
Ruggiero A, Squeglia F, Marasco D, Marchetti R, Molinaro A, Berisio R
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2011 Apr 1; 435(1): 33-41.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (95 visite)
Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
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* Dynamical properties of cold shock protein A from Mycobacterium tuberculosis (102 visite)
D'Auria G, Esposito C, Falcigno L, Calvanese L, Iaccarino E, Ruggiero A, Pedone C, Pedone E, Berisio R
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic), 2010 Nov 26; 402(4): 693-698.
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* Expression, purification, crystallization and preliminary x-ray crystallographic analysis of the peptidoglycan binding region of the ser/thr kinase PrkC from staphylococcus aureus (92 visite)
Ruggiero A, Squeglia F, Izzo V, Silipo A, Vitagliano L, Molinaro A, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2010 Oct; 17(10): 1296-1299.
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* Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (120 visite)
Ruggiero A, Marasco D, Squeglia F, Soldini S, Pedone E, Pedone C, Berisio R
Structurestructure (ISSN: 0969-2126, 1878-4186), 2010 Sep 8; 18(9): 1184-1190.
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* Elongation Factors Efia And Ef-Tu: Their Role In Translation And Beyond (111 visite)
Berisio R, Ruggiero A, Vitagliano L
Israel Journal Of Chemistry, 2010 Jun; 50(1): 71-79.
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* Nobel prize in chemistry 2009: When biology turns into chemistry (78 visite)
Berisio R, Baram D, Keinan E
Isr J Chem (ISSN: 0021-2148), 2010 Jun; 50(1): 24-26.
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* Dimerisation and structural integrity of Heparin Binding Hemagglutinin A from Mycobacterium tuberculosis: Implications for bacterial agglutination (118 visite)
Esposito C, Carullo C, Pedone E, Graziano G, Del Vecchio P, Berisio R
Febs Lett (ISSN: 0014-5793, 0014-5793print, 0014-5793linking), 2010 Mar 19; 584(6): 1091-1096.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (85 visite)
Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
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* Ribosome Inactivating Proteins from P. dioica leaves (62 visite)
Parente A, Berisio R, Chambery A, Di Maro A
Springer Eds, 2010; N/D: N/D-N/D.
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* The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves (93 visite)
Severino V, Chambery A, Di Maro A, Marasco D, Ruggiero A, Berisio R, Giansanti F, Ippoliti R, Parente A
Mol Biosyst (ISSN: 1742-206x), 2010; 6(3): 570-579.
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* Crystal structure of PD-L1, a ribosome inactivating protein from Phytolacca dioica L. leaves with the property to induce DNA cleavage (117 visite)
Ruggiero A, Di Maro A, Severino V, Chambery A, Berisio R
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1135-1142.
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* Comment on Microfibrillar structure of type i collagen in situ by Orgel et al. (2006), Proc. Natl Acad. Sci. USA, 103, 9001-9005 (100 visite)
Okuyama K, Baechinger HP, Mizuno K, Boudko S, Engel J, Berisio R, Vitagliano L
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2009 Sep; 65(9): 1007-1008.
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* Molecular dynamics studies of the P pilus rod subunit PapA (100 visite)
Vitagliano L, Ruggiero A, Pedone C, Berisio R
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 192-199.
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* Ribosome's mode of function: Myths, facts and recent results (82 visite)
Wekselman I, Davidovich C, Agmon I, Zimmerman E, Rozenberg H, Bashan A, Berisio R, Yonath A
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 122-130.
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* Role of side chains in collagen triple helix stabilization and partner recognition (293 visite)
Berisio R, De Simone A, Ruggiero A, Improta R, Vitagliano L
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 131-140.
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* Crystal Structure of the Resuscitation-Promoting Factor (Delta DUF)RpfB from M. tuberculosis (106 visite)
Ruggiero A, Tizzano B, Pedone E, Pedone C, Wilmanns M, Berisio R
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009 Jan 9; 385(1): 153-162.
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* Phase behavior and crystallogenesis under counter-diffusion conditions of the collagen-model peptide (Pro-Pro-Gly)10 (95 visite)
Vergara A, Castagnolo D, Carotenuto L, Vitagliano L, Berisio R, Sorrentino G, Gonzalez-ramirez L, Garcia-ruiz J, Zagari A
J Cryst Growth (ISSN: 0022-0248), 2009 Jan 1; 311(2): 304-309.
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* Conformational states and association mechanism of Yersinia pestis Caf1 subunits (88 visite)
Vitagliano L, Ruggiero A, Pedone C, Berisio R
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic), 2008 Sep 8; 372(4): 804-810.
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* Role of hydration in collagen triple helix stabilization (113 visite)
De Simone A, Vitagliano L, Berisio R
Biochem Biophys Res Commun (ISSN: 0006-291x), 2008 Jul 18; 372(1): 121-125.
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* Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis (91 visite)
Esposito C, Pethoukov MV, Svergun DI, Ruggiero A, Pedone C, Pedone E, Berisio R
J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530), 2008 Jul; 190(13): 4749-4753.
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* Contribution of dipole-dipole interactions to the stability of the collagen triple helix (87 visite)
Improta R, Berisio R, Vitagliano L
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2008 May; 17(5): 955-961.
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* Atomic Resolution (1. 1 Angstrom) Structure Of The Ribosome-Inactivating Protein Pd-L4 From Phytolacca Dioica L. Leaves (107 visite)
Ruggiero A, Chambery A, Di Maro A, Parente A, Berisio R
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2008 Apr; 71(1): 8-15.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (77 visite)
Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
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* A Molecular Dynamics Study of Pilus Subunits: Insights into Pilus Biogenesis (130 visite)
Vitagliano L, Ruggiero A, Pedone C, Berisio R
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2007 Apr 6; 367(4): 935-941.
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* Fate of prions in soil: Interaction of a recombinant ovine prion protein with synthetic humic-like mineral complexes (90 visite)
Rao M, Russo F, Granata V, Berisio R, Zagari A, Gianfreda L
Soil Biol Biochem (ISSN: 0038-0717), 2007 Feb; 39(2): 493-504.
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* Crystallization and preliminary X-ray diffraction analysis of PD-L1, a highly glycosylated ribosome inactivating protein with DNase activity (74 visite)
Ruggiero A, Chambery A, Di Maro A, Mastroianni A, Parente A, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2007; 14(4): 407-409.
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* Crystallization and preliminary x-ray diffraction analysis of PD-L4, a ribosome inactivating protein from Phytolacca dioica L. leaves (115 visite)
Ruggiero A, Chambery A, Di Maro A, Pisante M, Parente A, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2007; 14(1): 97-100.
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* Limited Tendency Of Alpha-Helical Residues To Form Disulfide Bridges: A Structural Explanation (143 visite)
De Simone A, Berisio R, Zagari A, Vitagliano L
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 740-747.
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* 23S rRNA 2058A→G alteration mediates ketolide resistance in combination with deletion in L22 (81 visite)
Berisio R, Corti N, Pfister P, Yonath A, Böttger EC
Antimicrobial Agents And Chemotherapy (ISSN: 0066-4804, 1098-6596), 2006 Nov; 50(11): 3816-3823.
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* The effect of the osmolyte trimethylamine N-oxide on the stability of the prion protein at low pH (75 visite)
Granata V, Palladino P, Tizzano B, Negro A, Berisio R, Zagari A
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2006 Jun 15; 82(3): 234-240.
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* Polyproline helices in protein structures: A statistical survey (94 visite)
Berisio R, Loguercio S, De Simone A, Zagari A, Vitagliano L
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2006; 13(8): 847-854.
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* A crevice adjoining the ribosome tunnel: Hints for cotranslational folding (124 visite)
Amit M, Berisio R, Baram D, Harms J, Bashan A, Yonath A
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2005 Jun 13; 579(15): 3207-3213.
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* Productive And Non-Productive Binding Of Polyketides To The Ribosome Large Subunit (80 visite)
Berisio R, Amit M, Baram D, Harms J, Bashan A, Hansen H, Schluenzen F, Yonath A
Acta Crystallogr D Biol Crystallogr, 2005; N/D: 61-61.
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* Imino acids and collagen triple helix stability: Characterization of collagen-like polypeptides containing Hyp-Hyp-Gly sequence repeats (128 visite)
Berisio R, Granata V, Vitagliano L, Zagari A
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2004 Sep 22; 126(37): 11402-11403.
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* Ribosomal crystallography: A flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism (73 visite)
Agmon I, Amit M, Auerbach T, Bashan A, Baram D, Bartels H, Berisio R, Greenberg I, Harms J, Hansen HAS, Kessler M, Pyetan E, Schluenzen F, Sittner A, Yonath A, Zarivach R
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2004 Jun 1; 567(1): 20-26.
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* Characterization of Collagen-Like Heterotrimers: Implications for Triple-Helix Stability (113 visite)
Berisio R, Granata V, Vitagliano L, Zagari A
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004 Apr 15; 73(6): 682-688.
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* Functional aspects of ribosomal architecture: Symmetry, chirality and regulation (75 visite)
Zarivach R, Bashan A, Berisio R, Harms J, Auerbach T, Schluenzen F, Bartels H, Baram D, Pyetan E, Sittner A, Amit M, Hansen HAS, Kessler M, Liebe C, Wolff A, Agmon I, Yonath A
J Phys Org Chem (ISSN: 0894-3230), 2004; 17(11): 901-912.
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* Crystal Structure Of The Dimeric Un-Swapped Form Of Bovine Seminal Ribonuclease (112 visite)
Berisio R, Sica F, De Lorenzo C, Di Fiore A, Piccoli R, Zagari A, Mazzarella L
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2003 Nov 6; 554(1-2): 105-110.
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* Ribosomal crystallography: Peptide bond formation and its inhibition (121 visite)
Bashan A, Zarivach R, Schluenzen F, Agmon I, Harms J, Auerbach T, Baram D, Berisio R, Bartels H, Hansen HAS, Fucini P, Wilson D, Peretz M, Kessler M, Yonath A
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003 Sep; 70(1): 19-41.
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* Structural insight into the antibiotic action of telithromycin against resistant mutants (89 visite)
Berisio R, Harms J, Schluenzen F, Zarivach R, Hansen HAS, Fucini P, Yonath A
J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530), 2003 Jul; 185(14): 4276-4279.
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* On Peptide Bond Formation, Translocation, Nascent Protein Progression And The Regulatory Properties Of Ribosomes. Derived On 20 October 2002 At The 28th Febs Meeting In Istanbul (85 visite)
Agmon I, Auerbach T, Baram D, Bartels H, Bashan A, Berisio R, Fucini P, Hansen HA, Harms J, Kessler M, Peretz M, Schluenzen F, Yonath A, Zarivach R
Chembiochem, 2003 Jun; 270(12): 2543-2556.
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* Structural insight into the role of the ribosomal tunnel in cellular regulation (94 visite)
Berisio R, Schluenzen F, Harms J, Bashan A, Auerbach T, Baram D, Yonath A
Nat Struct Biol (ISSN: 1072-8368), 2003 May; 10(5): 366-370.
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* Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression (119 visite)
Bashan A, Agmon I, Zarivach R, Schluenzen F, Harms J, Berisio R, Bartels H, Franceschi F, Auerbach T, Hansen HAS, Kossoy E, Kessler M, Yonath A
Molecular Cell (ISSN: 1097-2765, 1097-4164), 2003 Jan; 11(1): 91-102.
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* Methods Of Growing Crystals Of Free, Antibiotic-Complexed, And Substrate-Complexed Large Ribosomal Subunits, And Methods Of Rational Designing Or Identifying Antibiotics Using Structure Coordinate Data Derived From Such Crystals (101 visite)
Yonath A, Bashan A, Zarivach R, Franceschi F, Schluenzen F, Harms J, Albrecht R, Berisio R
International Publication Number, 2003; N/D: N/D-N/D.
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* Crystallization of the collagen-like polypeptide (PPG)10 aboard the International Space Station. 2. Comparison of crystal quality by X-ray diffraction (111 visite)
Berisio R, Vitagliano L, Vergara A, Sorrentino G, Mazzarella L, Zagari A
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2002 Oct; 58(10II): 1695-1699.
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* Recent progress on collagen triple helix structure, stability and assembly (90 visite)
Berisio R, Vitagliano L, Mazzarella L, Zagari A
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2002 Apr; 9(2): 107-116.
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* Crystal structure of the collagen triple helix model [(Pro-Pro-Gly)10]3 (92 visite)
Berisio R, Vitagliano L, Mazzarella L, Zagari A
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2002 Feb; 11(2): 262-270.
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* Atomic resolution structures of ribonuclease A at six pH values (194 visite)
Berisio R, Sica F, Lamzin VS, Wilson KS, Zagari A, Mazzarella L
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2002; 58(3): 441-450.
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* Atomic Resolution Structures Of Rnase A At Six Ph Values (81 visite)
Berisio R, Sica F, Lamzin VS, Wilson KS, Zagari A, Mazzarella L
Acta Crystallogr D Biol Crystallogr, 2002; N/D: 441-450.
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* Preferred proline puckerings in cis and trans peptide groups: Implications for collagen stability (104 visite)
Vitagliano L, Berisio R, Mastrangelo A, Mazzarella L, Zagari A
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2001 Dec; 10(12): 2627-2632.
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* Structural bases of collagen stabilization induced by proline hydroxylation (98 visite)
Vitagliano L, Berisio R, Mazzarella L, Zagari A
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2001 Apr 15; 58(5): 459-464.
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* Atomic resolution structure of a mutant of the spectrin SH3 domain (83 visite)
Berisio R, Viguera A, Serrano L, Wilmanns M
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2001 Feb; 57(2): 337-340.
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* Depletion Zone Around Sedimenting Protein Crystals In Microgravity (80 visite)
Carotenuto L, Cartwright J, Otálora F, Garcia-ruiz J, Castagnolo D, Piccolo C, Berisio R, Vitagliano L, Mazzarella L, Zagari A
Esa Journal, 2001; 454: 323-329.
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* Erratum: Structural bases of collagen stabilization induced by proline Hydroxylation (Biopolymers (2001) 58: 5 (459-464)) (124 visite)
Vitagliano L, Berisio R, Mazzarella L, Zagari A
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2001; 59(6): 465-465.
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* Video observation of protein crystal growth in the advanced protein crystallization facility aboard the space shuttle mission STS-95 (84 visite)
Carotenuto L, Berisio R, Piccolo C, Vitagliano L, Zagari A
J Cryst Growth (ISSN: 0022-0248), 2001; 232(1-4): 481-488.
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Effects of microgravity on the crystal quality of a collagen-like polypeptide (87 visite)
Berisio R, Vitagliano L, Sorrentino G, Carotenuto L, Piccolo C, Mazzarella L, Zagari A
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2000 Jan; 56(1): 55-61.
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Biomolecule crystallisation in microgravity (70 visite)
Carotenuto L, Castagnolo D, Piccolo C, Berisio R, Vitagliano L, Mazzarella L, Zagari A
Eur Space Agency Spec Publ Esa Sp (ISSN: 0379-6566), 2000; (454I): 437-443.
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Crystal Structure Of A Collagen-Like Polypeptide With Repeating Sequence Pro-Hyp-Gly At 1. 4 Ang Resolution: Implications For Collagen Hydration (99 visite)
Berisio R, Vitagliano L, Mazzarella L, Zagari A
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 8-13.
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Reversible domain motions induced by substrate binding in ribonuclease (68 visite)
ZagariA, Berisio R, Merlino A, Sica F, Vitagliano L, Mazzarella L
Acta Crystallographica Section A, 2000; 56: 263-263.
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Protein titration in the crystal state (75 visite)
Berisio R, Lamzin VS, Sica F, Wilson KS, Zagari A, Mazzarella L
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Oct 1; 292(4): 845-854.
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Thermodynamic analysis of α-spectrin SH3 and two of its circular permutants with different loop lengths: Discerning the reasons for rapid folding in proteins (83 visite)
Martínez JC, Viguera AR, Berisio R, Wilmanns M, Mateo PL, Filimonov VV, Serrano L
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 1999 Jan 12; 38(2): 549-559.
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Crystallization of multiple forms of bovine seminal ribonuclease in the liganded and unliganded state (92 visite)
Sica F, Adinolfi S, Berisio R, De Lorenzo C, Mazzarella L, Piccoli R, Vitagliano L, Zagari A
J Cryst Growth (ISSN: 0022-0248), 1999; 196(2-4): 305-312.
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X-ray crystallographic determination of a collagen-like peptide with the repeating sequence (Pro-Pro-Gly) (104 visite)
Kramer RZ, Vitagliano L, Bella J, Berisio R, Mazzarella L, Brodsky B, Zagari A, Berman HM
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1998 Jul 24; 280(4): 623-638.
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Protein Crystal Growth In The Advance Protein Crystallisation Facility On The Lms Mission: A Comparison Of Sulfolobus Solfataricus Alchool Dehydrogenase Crystals Grown On The Ground And In Microgravity (68 visite)
 Esposito L, Sica F, Sorrentino G, Berisio R, Carotenuto L, Giordano A, Raia C, Rossi M, Lamzin VS, Willson KS, Zagari A
Acta Crystallogr D Biol Crystallogr, 1998; 54: 386-390.
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Protein crystal growth in the advanced protein crystallization facility on the LMS mission: A comparison of Sulfolobus solfataricus alcohol dehydrogenase crystals grown on the ground and in microgravity (95 visite)
Esposito L, Sica F, Sorrentino G, Berisio R, Carotenuto L, Giordano A, Raia CA, Rossi M, Lamzin VS, Wilson KS, Zagari A
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 1998; 54(3): 386-390.
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