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NomeDaniela Marasco
AreaAssociati
QualificaAssociato
SedeNapoli-Mezzocannone
IndirizzoVia Mezzocannone 16, 80134 Napoli - Italia
E-maildaniela.marascounina.it
Telefono ufficio+39 081-2534512
Nessuna area di ricerca
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Daniela Marasco graduated in chemistry in 1998, at the University of Naples Federico II  in Bioinorganic Chemistry and in 2002 she attained Doctorate in Chemical Sciences. From 2002 to 2009 she worked at the Insitute of Biostructures and Bioimaging (IBB) of the Italian Research National Council as post-doc. From 2009 she is Reseacher of General Chemistry. She is teacher of  “General Chemistry” and Techniques of Structural Biology” at University of Naples "Federico II".

The research activities of Daniela Marasco are focused on the relationships between structure and activities of biological macromolecules. Primarily the chemical synthesis of proteins, peptides and peptidomimetics, single and as libraries. The identifications of peptide-based molecules as modulators of protein-protein interactions. These research topics are carried out by combining chemical synthetic routes, mass-spectrometry, spectroscopic techniques (circular dicroism, Fluorescence) and biochemical binding assays as ELISA, SPR, ITC, FRET.

Dr. Marasco is co-author of about 107 publications on international journals (among which  Nature Communication, Oncotarget, JACS, PNAS, NAR, Stem Cells), book chapters, and four patents.


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Bibliografia
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* Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2 (26 visite)
Mercurio FA, Pirone L, Di Natale C, Marasco D, Pedone EM, Leone M
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2018 Oct; 80: 602-610.
Impact Factor: 3.9
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Evaluating the biological properties of synthetic 4-nitrophenyl functionalized benzofuran derivatives with telomeric DNA binding and antiproliferative activities (51 visite)
Carella A, Roviello V, Iannitti R, Palumbo R, La Manna S, Marasco D, Trifuoggi M, Diana R, Roviello  GN
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2018 Sep 25; 121: 77-88.
Impact Factor: 4.11
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Evaluating the biological properties of synthetic 4-nitrophenyl functionalized benzofuran derivatives with telomeric DNA binding and antiproliferative activities (3 visite)
Carella A, Roviello V, Iannitti R, Palumbo R, La Manna S, Marasco D, Trifuoggi M, Diana R, Roviello GN
International Journal Of Biological Macromolecules, 2018 Sep 25; 121: 77-88.
Impact Factor: 4.11
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Streptococcal Collagen-like Protein 1 Binds Wound Fibronectin: Implications in Pathogen Targeting (25 visite)
Mcnitt DH, De Water LV, Marasco D, Berisio R, Lukomski S
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2018 Aug 31; N/D: N/D-N/D.
Impact Factor: 3.469
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors (66 visite)
Mercurio FA, Di Natale C, Pirone L, Iannitti R, Marasco D, Pedone EM, Palumbo R, Leone M
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2017 Dec 12; 7(1): 17474-17474.
Impact Factor: 4.259
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structure-activity studies of peptidomimetics based on kinase-inhibitory region of suppressors of cytokine signaling (59 visite)
La Manna S, Lopez-sanz L, Leone M, Brandi P, Scognamiglio PL, Morelli G, Novellino E, Gomez-guerrero C, Marasco D
Biopolymers (ISSN: 1097-0282electronic, 0006-3525linking, 0006-3525print), 2017 Nov 20; N/D: N/D-N/D.
Impact Factor: 2.572
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural investigation of a C-terminal EphA2 receptor mutant: Does mutation affect the structure and interaction properties of the Sam domain? (58 visite)
Mercurio FA, Costantini S, Di Natale C, Pirone L, Guariniello S, Scognamiglio PL, Marasco D, Pedone EM, Leone M
Biochim Biophys Acta (ISSN: 0006-3002print, 0006-3002linking, 0005-2728), 2017 Jun 06; 1865(9): 1095-1104.
Impact Factor: 2.6
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Mitochondria Targeting with Luminescent Rhenium(I) Complexes (58 visite)
Skiba J, Bernas T, Trzybinski D, Wozniak K, Ferraro G, Marasco D, Merlino A, Shafikov MZ, Czerwieniec R, Kowalski K
Molecules (ISSN: 1420-3049electronic, 1420-3049linking), 2017 May 15; 22(5): N/D-N/D.
Impact Factor: 2.386
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Characterization of linear mimetic peptides of Interleukin-22 from dissection of protein interfaces (94 visite)
La Manna S, Scognamiglio PL, Di Natale C, Leone M, Mercurio FA, Malfitano AM, Cianfarani F, Madonna S, Caravella S, Albanesi C, Novellino E, Marasco D
Biochimie (ISSN: 1638-6183electronic, 0300-9084linking), 2017 May 04; N/D: N/D-N/D.
Impact Factor: 3.112
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Targeting EphA2-Sam and Its Interactome: Design and Evaluation of Helical Peptides Enriched in Charged Residues (116 visite)
Mercurio FA, Marasco D, Di Natale C, Pirone L, Costantini S, Pedone EM, Leone M
Chembiochem (ISSN: 1439-7633electronic, 1439-4227linking), 2016 Nov 17; 17(22): 2179-2188.
Impact Factor: 2.847
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Unique Footprint in the scl1. 3 Locus Affects Adhesion and Biofilm Formation of the Invasive M3-Type Group A Streptococcus (121 visite)
Bachert BA, Choi SJ, Lasala PR, Harper TI, Mcnitt DH, Boehm DT, Caswell CC, Ciborowski P, Keene DR, Flores AR, Musser JM, Squeglia F, Marasco D, Berisio R, Lukomski S
Front Cell Infect Microbiol (ISSN: 2235-2988electronic, 2235-2988linking), 2016 Aug 31; 6: 90-90.
Impact Factor: 4.3
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia (121 visite)
Scognamiglio PL, Di Natale C, Leone M, Cascella R, Cecchi C, Lirussi L, Antoniali G, Riccardi D, Morelli G, Tell G, Chiti F, Marasco D
Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2016 Aug 1; N/D: N/D-N/D.
Impact Factor: 5.168
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Diolein based nanostructures as targeted theranostics (142 visite)
Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
Journal Of Biomedical Nanotechnology (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
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* Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions (115 visite)
Di Natale C, Scognamiglio PL, Cascella R, Cecchi C, Russo A, Leone M, Penco A, Relini A, Federici L, Di Matteo A, Chiti F, Vitagliano L, Marasco D
The Faseb Journal (ISSN: 1530-6860, 1530-6860electronic), 2015 Sep; 29(9): 3689-3701.
Impact Factor: 5.043
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Osteogenic properties of a short BMP-2 chimera peptide (117 visite)
Falcigno L, D'Auria G, Calvanese L, Marasco D, Iacobelli R, Scognamiglio PL, Brun P, Danesin R, Pasqualin M, Castagliuolo I, Dettin M
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2015; 21(9): 700-709.
Impact Factor: 1.951
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Oxaliplatin vs. cisplatin: Competition experiments on their binding to lysozyme (81 visite)
Marasco D, Messori L, Marzo T, Merlino A
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2015; 44(22): 10392-10398.
Impact Factor: 4.177
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam (139 visite)
Mercurio FA, Di Natale C, Pirone L, Scognamiglio PL, Marasco D, Pedone EM, Saviano M, Leone M
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2015; 16(11): 1629-1636.
Impact Factor: 2.85
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Synthetic and structural routes for the rational conversion of peptides into small molecules (178 visite)
Scognamiglio PL, Morelli G, Marasco D
Methods Mol Biol (ISSN: 1064-3745, 1940-6029electronic, 1064-3745linking), 2015; 1268: 159-193.
Impact Factor: 3.221
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Cd And Nmr Conformational Studies Of A Peptide Encompassing The Mid Loop Interface Of Ship2-Sam (102 visite)
Mercurio FA, Scognamiglio PL, Di Natale C, Marasco D, Pellecchia M, Leone M
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Nov; 101(11): 1088-1098.
Impact Factor: 2.385
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interaction between Proteins and Ir Based CO Releasing Molecules: Mechanism of Adduct Formation and CO Release (128 visite)
Petruk AA, Vergara A, Marasco D, Bikiel D, Doctorovich F, Estrin DA, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2014 Oct 6; 53(19): 10456-10462.
Impact Factor: 4.762
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Lead Optimization of P5U and Urantide: Discovery of Novel Potent Ligands at the Urotensin-II Receptor (153 visite)
Carotenuto A, Auriemma L, Merlino F, Yousif AM, Marasco D, Limatola A, Campiglia P, Gomez-Monterrey I, Santicioli P, Meini S, Maggi CA, Novellino E, Grieco P
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2014 Jul 24; 57(14): 5965-5974.
Impact Factor: 5.447
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis (131 visite)
Calvanese L, Falcigno L, Maglione C, Marasco D, Ruggiero A, Squeglia F, Berisio R, D'Auria G
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Jul; 101(7): 712-719.
Impact Factor: 2.385
Dettagli    Esporta in BibTeX    Esporta in EndNote

* G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection (116 visite)
Scognamiglio PL, Di Natale C, Leone M, Poletto M, Vitagliano L, Tell G, Marasco D
Biochim Biophys Acta (ISSN: 0006-3002print, 0006-3002linking, 0005-2728), 2014 Jun; 1840(6): 2050-2059.
Impact Factor: 5.353
Dettagli    Esporta in BibTeX    Esporta in EndNote

* SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements (163 visite)
Antoniali G, Lirussi L, D'Ambrosio C, Dal Piaz F, Vascotto C, Casarano E, Marasco D, Scaloni A, Fogolari F, Tell G
Molecular Biology Of The Cell (ISSN: 1059-1524), 2014 Feb 15; 25(4): 532-547.
Impact Factor: 4.466
Dettagli    Esporta in BibTeX    Esporta in EndNote

* IL-32 Promotes Angiogenesis (194 visite)
Nold-Petry CA, Rudloff I, Baumer Y, Ruvo M, Marasco D, Botti P, Farkas L, Cho SX, Zepp JA, Azam T, Dinkel H, Palmer BE, Boisvert WA, Cool CD, Taraseviciene-Stewart L, Heinhuis B, Joosten LA, Dinarello CA, Voelkel NF, Nold MF
Journal Of Immunology (ISSN: 0022-1767), 2014 Jan 15; 192(2): 589-602.
Impact Factor: 4.922
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Interactions of gold-based drugs with proteins: the structure and stability of the adduct formed in the reaction between lysozyme and the cytotoxic gold(III) compound Auoxo3 (135 visite)
Russo Krauss I, Messori L, Cinellu MA, Marasco D, Sirignano R, Merlino A
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2014; 43(46): 17483-17488.
Impact Factor: 4.197
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Therapeutical potential of a peptide mimicking the SOCS1 kinase inhibitory region in skin immune responses (116 visite)
Madonna S, Scarponi C, Doti N, Carbone T, Cavani A, Scognamiglio PL, Marasco D, Albanesi C
Eur J Immunol (ISSN: 0014-2980), 2013 Jul; 43(7): 1883-1895.
Impact Factor: 4.518
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Intrinsic Stability Of The Human Prion Beta-Sheet Region Investigated By Molecular Dynamics (158 visite)
De Simonea A, Stanzione F, Marasco D, Vitagliano L, Esposito L
Journal Of Biomolecular Structure & Dynamics, 2013 May 1; 31(5): 441-452.
Impact Factor: 2.983
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Role of mutual interactions in the chemical and thermal stability of nucleophosmin NPM1 domains (94 visite)
Marasco D, Ruggiero A, Vascotto C, Poletto M, Scognamiglio PL, Tell G, Vitagliano L
Biochemical And Biophysical Research Communications (ISSN: 0006-291x), 2013 Jan 11; 430(2): 523-528.
Impact Factor: 2.281
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Heterotypic Sam-Sam Association Between Odin-Sam1 And Arap3-Sam: Binding Affinity And Structural Insights (102 visite)
Mercurio FA, Marasco D, Pirone L, Scognamiglio PL, Pedone E, Pellecchia M, Leone M
Chembiochem (ISSN: 1439-4227, 1439-9422, 1439-7633), 2013 Jan 2; 14(1): 100-106.
Impact Factor: 2.92
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Evolutionary screening and adsorption behavior of engineered M13 bacteriophage and derived dodecapeptide for selective decoration of gold interfaces (124 visite)
Causa F, Della Moglie R, Iaccino E, Mimmi S, Marasco D, Scognamiglio PL, Battista E, Palmieri C, Cosenza C, Sanguigno L, Quinto I, Scala G, Netti PA
J Colloid Interface Sci (ISSN: 0021-9797, 1095-7103electronic, 0021-9797linking), 2013 Jan 1; 389(1): 220-229.
Impact Factor: 1.646
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Role Of The Unstructured N-Terminal Domain Of The Human Apurinic/Apyrimidinic Endonuclease 1 (hape1) In The Modulation Of Its Interaction With Nucleic Acids And Nucleophosmin (npm1) (127 visite)
Poletto M, Vascotto C, Scognamiglio PL, Lirussi L, Marasco D, Tell G
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2013; 452(3): 545-557.
Impact Factor: 4.779
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells (99 visite)
Lirussi L, Antoniali G, Vascotto C, D'Ambrosio C, Poletto M, Romanello M, Marasco D, Leone M, Quadrifoglio F, Bhakat KK, Scaloni A, Tell G
Molecular Biology Of The Cell (ISSN: 1059-1524), 2012 Oct 15; 23(20): 4079-4096.
Impact Factor: 4.803
Dettagli    Esporta in BibTeX    Esporta in EndNote

* HIV p24 as Scaffold for Presenting Conformational HIV Env Antigens (144 visite)
Tagliamonte M, Marasco D, Ruggiero A, de Stradis A, Tornesello ML, Totrov M, Buonaguro FM, Buonaguro L
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2012 Sep 17; 7(8): N/D-N/D.
Impact Factor: 3.73
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Acetylation on critical lysine residues of Apurinic/apyrimidinic endonuclease 1 (APE1) in triple negative breast cancers (105 visite)
Poletto M, Di Loreto C, Marasco D, Poletto E, Puglisi F, Damante G, Tell G
Biochemical And Biophysical Research Communications (ISSN: 0006-291x), 2012 Jul 20; 424(1): 34-39.
Impact Factor: 2.406
Dettagli    Esporta in BibTeX    Esporta in EndNote

* New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries (152 visite)
Doti N, Scognamiglio PL, Madonna S, Scarponi C, Ruvo M, Perretta G, Albanesi C, Marasco D
Biochemical Journal, 2012 Apr 1; 443: 231-240.
Impact Factor: 4.779
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor (106 visite)
Mercurio FA, Marasco D, Pirone L, Pedone E, Pellecchia M,  Leone M
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2012 Mar 13; 51(10): 2136-2145.
Impact Factor: 3.377
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy (90 visite)
Squeglia F, Marchetti R, Ruggiero A, Lanzetta R, Marasco D, Dworkin J, Petoukhov M, Molinaro A, Berisio R, Silipo A
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2011 Dec 28; 133(51): 20676-20679.
Impact Factor: 9.907
Dettagli    Esporta in BibTeX    Esporta in EndNote

* GSM48878: CD8 IL2-D2 (101 visite)
Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
Gene Expression Omnibus, 2011 Dec 2; 59(2): 302-308.
Impact Factor: 2.082
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Mimetic peptides of suppressor of cytokine signaling (SOCS)1 impair inflammatory responses of epidermal keratinocytes in vitro and in a mouse skin model of allergic contact dermatitis (112 visite)
Madonna S, Scarponi C, Sestito R, Doti N, Carbone T, Nasorri F, Marasco D, Cavani A, Albanesi C
Journal Of Investigative Dermatology (ISSN: 0022-202x), 2011 Sep; 131: N/D-N/D.
Impact Factor: 6.314
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural and functional insights into IkappaB-alpha/HIV-1 Tat interaction (140 visite)
Vitagliano L, Fiume G, Scognamiglio PL, Doti N, Cannavo R, Puca A, Pedone C, Scala G, Quinto I, Marasco D
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2011 Sep; 93(9): 1592-1600.
Impact Factor: 3.022
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Heparin-binding hemagglutinin HBHA from Mycobacterium tuberculosis affects actin polymerisation (89 visite)
Esposito C, Marasco D, Delogu G, Pedone E, Berisio R
Biochem Biophys Res Commun (ISSN: 0006-291x), 2011 Jul 1; 410(2): 339-344.
Impact Factor: 2.484
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (153 visite)
Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2011 May; 77(5): 319-327.
Impact Factor: 2.282
Dettagli    Esporta in BibTeX    Esporta in EndNote

* X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus (127 visite)
Ruggiero A, Squeglia F, Marasco D, Marchetti R, Molinaro A, Berisio R
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2011 Apr 1; 435(1): 33-41.
Impact Factor: 4.897
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions (110 visite)
Fantini D, Vascotto C, Marasco D, D'Ambrosio C, Romanello M, Vitagliano L, Pedone C, Poletto M, Cesaratto L, Quadrifoglio F, Scaloni A, Radicella JP, Tell G
Nucleic Acids Res (ISSN: 1362-4962, 0305-1048, 1362-4962electronic), 2010 Dec; 38(22): 8239-8256.
Impact Factor: 7.836
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural Investigations on the Nodal-Cripto Binding: A Theoretical and Experimental Approach (108 visite)
Calvanese L, Marasco D, Doti N, Saporito A, D'Auria G, Paolillo L, Ruvo M, Falcigno L
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 Nov; 93(11): 1011-1021.
Impact Factor: 2.572
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* Residues 762-801 of PLD1 mediate the interaction with PED/PEA15 (99 visite)
Doti N, Cassese A, Marasco D, Paturzo F, Sabatella M, Viparelli F, Dathan N, Monti SM, Miele C, Formisano P, Beguinot F, Ruvo M
Mol Biosyst (ISSN: 1742-206x), 2010 Oct; 6(10): 2039-2048.
Impact Factor: 3.825
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* Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (123 visite)
Ruggiero A, Marasco D, Squeglia F, Soldini S, Pedone E, Pedone C, Berisio R
Structurestructure (ISSN: 0969-2126, 1878-4186), 2010 Sep 8; 18(9): 1184-1190.
Impact Factor: 6.337
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* A Small Synthetic Cripto Blocking Peptide Improves Neural Induction, Dopaminergic Differentiation, and Functional Integration of Mouse Embryonic Stem Cells in a Rat Model of Parkinson's Disease (123 visite)
Lonardo E, Parish CL, Ponticelli S, Marasco D, Ribeiro D, Ruvo M, De Falco S, Arenas E, Minchiotti G
Stem Cells (ISSN: 1066-5099), 2010 Sep; 28(8): 1326-1337.
Impact Factor: 7.871
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* Covalently immobilized RGD gradient on PEG hydrogel scaffold influences cell migration parameters (116 visite)
Guarnieri D, De Capua A, Ventre M, Borzacchiello A, Pedone C, Marasco D, Ruvo M, Netti PA
Acta Biomaterialia (ISSN: 1878-7568, 1742-7061), 2010 Jul; 6(7): 2532-2539.
Impact Factor: 4.824
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* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (104 visite)
Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
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* Cell recruitment and transfection in gene activated collagen matrix (111 visite)
Orsi S, De Capua A, Guarnieri D, Marasco D, Netti PA
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2010 Jan; 31(3): 570-576.
Impact Factor: 7.883
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (101 visite)
Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
Impact Factor: 1.849
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* Amino acid transport in thermophiles: characterization of an arginine-binding protein in Thermotoga maritima (108 visite)
Luchansky MS, Der BS, D'Auria S, Pocsfalvi G, Iozzino L, Marasco D, Dattelbaum JD
Molecular Biosystems (ISSN: 1742-206x), 2010; 6(1): 142-151.
Impact Factor: 3.825
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves (97 visite)
Severino V, Chambery A, Di Maro A, Marasco D, Ruggiero A, Berisio R, Giansanti F, Ippoliti R, Parente A
Mol Biosyst (ISSN: 1742-206x), 2010; 6(3): 570-579.
Impact Factor: 3.825
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* Optimizing A Kinase Assay For Ikkbeta On An Hts Station (100 visite)
Doti N, Marasco D, Pedone C, Sabatella M, Ruvo M
J Biomol Screen (ISSN: 1087-0571, 1552-454x, 1552-454xelectronic), 2009 Dec; 14(10): 1263-1268.
Impact Factor: 2.395
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The dimeric structure of Sulfolobus solfataricus thioredoxin A2 and the basis of its thermostability (96 visite)
Ruggiero A, Masullo M, Marasco D, Ruocco MR, Grimaldi P, Arcari P, Zagari A, Vitagliano L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2009 Dec; 77(4): 1004-1008.
Impact Factor: 3.085
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Ige-Binding Properties And Selectivity Of Peptide Mimics Of The Fcvarepsilonri Binding Site (114 visite)
Sandomenico A, Monti SM, Marasco D, Dathan N, Palumbo R, Saviano M, Ruvo M
Mol Immunol Molecular Immunology (ISSN: 0161-5890), 2009 Oct; 46(16): 3300-3309.
Impact Factor: 3.202
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Generation And Functional Characterization Of A Bcl10-Inhibitory Peptide That Represses Nf-Kappa B Activation (118 visite)
Marasco D, Stilo R, Sandomenico A, Monti SM, Tizzano B, De Capua A, Varricchio E, Liguoro D, Zotti T, Formisano S, Ruvo M, Vito P
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2009 Sep 15; 422(3): 553-561.
Impact Factor: 5.155
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* Crystallization and preliminary X-ray crystallographic analysis of two dimeric hyperthermostable thioredoxins isolated from Sulfolobus solfataricus (99 visite)
Ruggiero A, Lanzotti MA, Ruocco MR, Grimaldi P, Marasco D, Arcari P, Masullo M, Zagari A, Vitagliano L
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2009 Jun; 65: 604-607.
Impact Factor: 0.551
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* Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists (120 visite)
Sandomenico A, Monti SM, Sabatella M, De Capua A, Tornatore L, Doti N, Viparelli F, Dathan NA, Pedone C, Ruvo M, Marasco D
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0285, 1747-0277), 2009 May; 73(5): 483-493.
Impact Factor: 2.473
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor (108 visite)
Calvanese L, Saporito A, Oliva R, D'Auria G, Pedone C, Paolillo L, Ruvo M, Marasco D, Falcigno L
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 175-183.
Impact Factor: 1.807
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity (130 visite)
Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M
J Mol Biol (ISSN: 1089-8638, 0022-2836, 1089-8638electronic), 2009 Feb 6; 385(5): 1556-1567.
Impact Factor: 3.871
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Gadd45beta dimerization does not affect MKK7 binding (107 visite)
Tornatore L, Montil SM, Marasco D, Dathan N, Vitale RM, Benedetti E, Pedone C, Papa S, Franzoso G, Ruvo M
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print), 2009; 611: 367-368.
Impact Factor: 2.02
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Peptide antagonists of the PED-hPLD1 binding (106 visite)
Viparelli F, Doti N, Monti SM, Marasco D, Dathan N, Pedone C, Miele C, Formisano P, Beguinot F, Ruvo M
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print, 0065-2598linking), 2009; 611: 445-446.
Impact Factor: 2.02
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Peptides binding the type E immunoglobulins (128 visite)
Sandomenico A, Marasco D, Monti SM, Saviano M, Pedone C, Benedetti E, Ruvo M
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print), 2009; 611: 573-574.
Impact Factor: 2.02
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Self-association regions in the CARD of Bcl-10 (107 visite)
Ruvo M, Sandomenico A, Marasco D, Monti SM, Tizzano B, De Capua A, Pedone C, Saporito A, Vitale RM, Formisano S, Stilo R, Liguoro D
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print), 2009; 611: 569-570.
Impact Factor: 2.02
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* Modulation of Angiogenesis by a Tetrameric Tripeptide That Antagonizes Vascular Endothelial Growth Factor Receptor (112 visite)
Ponticelli S, Marasco D, Tarallo V, Albuquerque RJC, Mitola S, Takeda A, Stassen J, Presta M, Ambati J, Ruvo M, De Falco S
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2008 Dec 5; 283(49): 34250-34259.
Impact Factor: 5.52
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Past and Future Perspectives of Synthetic Peptide Libraries (110 visite)
Marasco D, Perretta G, Sabatella M, Ruvo M
Curr Protein Pept Sci (ISSN: 1389-2037), 2008 Oct; 9(5): 447-467.
Impact Factor: 3.011
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells (104 visite)
Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2008 Sep 1; 283(31): 21769-21778.
Impact Factor: 5.52
Dettagli    Esporta in BibTeX    Esporta in EndNote

* An analysis of deletion mutants of the PLD1 D4 domain defines short regions within the PLD1 interacting with PED/PEA15: implications for the development of peptides-specific antagonist (139 visite)
Doti N, Marasco D, Sabatella M, Monti SM, Dathan N, Viparelli F, Cassese A, Miele C, Pedone C, Ruvo M
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Angiogenesis modulation: identification of tetrameric tripeptide as inhibitor of VEGFR-1 by the screening of peptide combinatiorial libraries (108 visite)
Ponticelli S, Takeda A, Mitola S, Stassen J, Presta M, Ambati J, Ruvo M, De Falco S, Marasco D
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Peptide antagonists of protein-protein interactions identified by screening protein fragments derived by enzyme degradation (102 visite)
Ruvo M, Marasco D, Viparelli F, Tornatore L, Sandomenico A, Doti N, Pedone C, Benedetti E, Monti SM
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15 (96 visite)
Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
Protein Expr Purif (ISSN: 1046-5928), 2008 Jun; 59(2): 302-308.
Impact Factor: 1.621
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Gadd45 beta forms a homodimeric complex that binds tightly to MKK7 (121 visite)
Tornatore L, Marasco D, Dathan N, Vitale RM, Benedetti E, Papa S, Franzoso G, Ruvo M, Monti SM
J Mol Biol (ISSN: 0022-2836, 0022-2283, 1089-8638), 2008 Apr 18; 378(1): 97-111.
Impact Factor: 5.673
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Anti-allergic properties of a new all-D synthetic immunoglobulin-binding peptide (83 visite)
Rossi M, Ruvo M, Marasco D, Colombo M, Cassani G, Verdoliva A
Mol Immunol Molecular Immunology (ISSN: 0161-5890), 2008 Jan; 45(1): 226-234.
Impact Factor: 3.555
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Dependence of cell migration parameters on steepness of RGD gradient slope (82 visite)
Guarnieri D, Borzacchiello A, De Capua A, Marasco D, Ruvo M, Netti PA
World Biomater Congr (ISSN: 9781-6156), 2008; 1: 271-271.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Abeta(25-35) And Its C- And/Or N-Blocked Derivatives: Copper Driven Structural Features And Neurotoxicity (153 visite)
Giuffrida ML, Grasso G, Ruvo M, Pedone C, Saporito A, Marasco D, Pignataro B, Cascio C, Copani A, Rizzarelli E
Journal Of Neuroscience Research (ISSN: 0360-4012), 2007 Feb 15; 85(3): 623-633.
Impact Factor: 3.268
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* Does Tetracycline Bind Helix 2 Of Prion? An Integrated Spectroscopical And Computational Study Of The Interaction Between The Antibiotic And Alpha Helix 2 Human Prion Protein Fragments (147 visite)
Ronga L, Langella E, Palladino P, Marasco D, Tizzano B, Saviano M, Pedone C, Improta R, Ruvo M
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Feb 15; 66(3): 707-715.
Impact Factor: 3.354
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The chemical synthesis of the GstI protein by NCL on a X-Met site (117 visite)
Saporito A, Marasco D, Chambery A, Botti P, Monti SM, Pedone C, Ruvo M
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2006 Dec 5; 83(5): 508-518.
Impact Factor: 2.48
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Effect of salts on the structural behavior of hPrP α2-helix-derived analogues: The counterion perspective (127 visite)
Ronga L, Palladino P, Tizzano B, Marasco D, Benedetti E, Ragone R, Rossi F
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 790-795.
Impact Factor: 1.801
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Solution structure of mouse Cripto CFC domain and its inactive variant Trp107Ala (115 visite)
Calvanese L, Saporito A, Marasco D, D'Auria G, Minchiotti G, Pedone C, Paolillo L, Falcigno L, Ruvo M
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Nov 30; 49(24): 7054-7062.
Impact Factor: 5.115
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Chemical synthesis of mouse Cripto CFC variants (104 visite)
Marasco D, Saporito A, Ponticelli S, Chambery A, De Falco S, Pedone C, Minchiotti G, Ruvo M
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Sep 15; 64(3): 779-788.
Impact Factor: 3.73
Dettagli    Esporta in BibTeX    Esporta in EndNote

* A new ligand for immunoglobulin G subdomains by screening of a synthetic peptide library (122 visite)
Verdoliva A, Marasco D, De Capua A, Saporito A, Bellofiore P, Manfredi V, Fattorusso R, Pedone C, Ruvo M
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2005 Jul; 6(7): 1242-1253.
Impact Factor: 3.94
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Human Prion Protein Alpha2 Helix: A Thermodynamic Study Of Its Conformational Preferences (109 visite)
Tizzano B, Palladino P, De Capua A, Marasco D, Rossi F, Benedetti E, Pedone C, Ragone R, Ruvo M
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2005 Apr 1; 59(1): 72-79.
Impact Factor: 4.684
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Chemical synthesis of the of Gstl protein by an NCL method on a X-Met site (93 visite)
Marasco D, Saporito A, Patriarca E, Fasulo R, Spasiano A, Pedone C, Benedetti E, Ruvo M
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2005; 80(4): N/D-N/D.
Impact Factor: 2.545
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Cripto protein sub-domains: synthesis and structural studies (109 visite)
Saporito A, Falcigno L, D'Auria G, Minchiotti G, Marasco D, Benedetti E, Pedone C, Ruvo M
Peptides 2004 Proceedings, 2005; N/D: N/D-N/D.
Impact Factor: 2.618
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Erratum: A new ligand for immunoglobulin G subdomains by screening of a synthetic peptide library (ChemBioChem (2005) 6 (1242-1253)) (83 visite)
Verdoliva A, Marasco D, De Capua A, Saporito A, Bellofiore P, Manfredi V, Fattorusso R, Pedone C, Ruvo M
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2005; 20(4): 1307-1307.
Impact Factor: 3.94
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* Conformational conversion of prion proteins: Role synthetic PRP 173-195 fibrillogenic peptide (112 visite)
Tizzano B, Marasco D, Benedetti E, De Capua A, Palladino P, Pedone C, Perretta G, Rossi F, Ragone R, Ruvo M
Peptide Revolution, 2004; N/D: N/D-N/D.
Impact Factor: 4.659
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* Design of a new mimochrome with unique topology (108 visite)
Lombardi A, Nastri F, Marasco D, Maglio O, De Sanctis G, Sinibaldi F, Santucci R, Coletta M, Pavone V
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2003 Nov 21; 9(22): 5643-5654.
Impact Factor: 4.353
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Miniaturized metalloproteins: Application to iron-sulfur proteins (332 visite)
Lombardi A, Marasco D, Maglio O, Di Costanzo L, Nasti F, Pavone V
Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2000 Oct 24; 97(22): 11922-11927.
Impact Factor: 10.789
Dettagli    Esporta in BibTeX    Esporta in EndNote



91 Records (81 escludendo Abstract e Conferenze).
Impact factor totale: 341.455 (310.954 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 342.713 (312.024 escludendo Abstract e Conferenze).








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