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Name NomeSonia Di Gaetano
AreaResearch&Development Ricerca e Sviluppo
Position QualificaResearcher Ricercatore
Work site SedeNaples-Mezzocannone Napoli-Mezzocannone
Address IndirizzoVia Mezzocannone 16, 80134 Naples - Italy Napoli - Italia
E-maildigaetanunina.it
Office phone Telefono ufficio+39 081 2532042
▼    Cancer Diseases Malattie Neoplastiche
▼    Gadd45 beta and its implication in chronic inflammation
▼    Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions
▼    Caratterizzazione della famiglia proteica delle KCTD: fattori chiave in diversi processi biologici Characterization of the KCTD protein family: key factors in several biological processes
▼    Characterization of neurotoxic and neuroprotective factors by using computational methodologies
▼    Monoclonal Antibodies for therapeutic and diagnostic applications
▼    Targeted Drug Delivery by integrin avb3 antagonist
▼    Sintesi chimica e modificazione di proteine per applicazioni in campo biomedico Chemical protein synthesis and modification for biomedical applications
▼    Biomolecole in grado di modulare l’angiogenesi VEGF-dipendente Biomolecules able to modulate the VEGF-dependent angiogenesis
▼    Imaging Tumor Acidosis
▼    Bioactive peptide-membrane assemblies
No results. Nessun risultato.
▼    Carbonic Anhydrase IX as target for the development of new anti-tumour drugs L’Anidrasi Carbonica IX come target per lo sviluppo di nuovi farmaci antitumorali
▼    Carbonic Anhydrase family as target for rational drug design
▼    Clinical Oncology
▼    Translational Molecular Imaging in Cancer
▼    Molecular imaging for personalized therapy in oncology
▼    Modeling radiation induced normal tissue effects
▼    Evaluation of new molecular probes by preclinical imaging Test e validazione di nuove sonde molecolari mediante imaging preclinico
▼    Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural product in biomedicine. Nucleic acid and protein binding studies Sintesi di small molecules, peptidi modificati e peptidi decorati con nucleobasi. Valutazione spettroscopica e computazionale del potenziale di prodotti naturali in biomedicina. Studi di interazione molecolare con acidi nucleici e proteine
▼    Brain segmentation for radiation oncology application Segmentazione cerebrale per applicazioni in radiologia oncologica
▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools Modifiche chimiche eseguite su molecole naturali, quali peptide e polisaccaridi, e loro impiego come agenti terapeutici e sonde diagnostiche
▼    Axl and Gas6 targeting for therapeutic and diagnostic applications Molecole che bersagliano Axl e Gas6 per applicazioni a scopo terapeutico e diagnostico
▼    Drug discovery by mirror-image phage display Drug discovery attraverso l’impiego della tecnologia del mirror-image phage display
▼    Macromolecules for biomedical and biotechnological applications Macromolecole per applicazioni biomediche e biotecnologiche
▼    Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives Relazione tra malattia e alterate interazioni proteina-proteina: patogenicità e prospettive terapeutiche
▼    A multi-targeting approach to fight COVID-19 Un approccio multi-targeting per combattere COVID-19
▼    Galectins: Structure, function and therapeutic potential inhibitors Galectine: struttura, funzione e potenziali inibitori terapeutici
▼    Caratterizzazione della famiglia proteica delle KCTD: fattori chiave in diversi processi biologici Characterization of the KCTD protein family: key factors in several biological processes
▼    Sintesi chimica e modificazione di proteine per applicazioni in campo biomedico Chemical protein synthesis and modification for biomedical applications
▼    Biomolecole in grado di modulare l’angiogenesi VEGF-dipendente Biomolecules able to modulate the VEGF-dependent angiogenesis
▼    Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications Risonanza magnetica nucleare biomolecolare: studi strutturali di proteine e peptidi e applicazioni per il “drug discovery”
▼    Axl and Gas6 targeting for therapeutic and diagnostic applications Molecole che bersagliano Axl e Gas6 per applicazioni a scopo terapeutico e diagnostico
▼    Generation of innovative scaffolds by manipulating hyperstable proteins Design di scaffold innovativi mediante l’ingegnerizzazione di proteine termostabili
▼    The fine structure of proteins as a new tool for protein structure validation, quality assessment, and prediction La strutture fine delle proteine: un nuovo strumento per la validazione e la predizione della loro struttura tridimensionale
▼    Carbonic Anhydrase IX as target for the development of new anti-tumour drugs L’Anidrasi Carbonica IX come target per lo sviluppo di nuovi farmaci antitumorali
▼    Biochemical and functional characterization of intrinsically disordered proteins (IDPs) in human diseases Caratterizzazione biochimica e funzionale di proteine intrinsecamente disordinate e loro ruolo nelle malattie umane
▼    Biochemical and functional characterization of Protein-Protein and DNA-protein Interaction networks in physio/pathological events Caratterizzazione biochimica e funzionale di interazioni proteina-proteina e DNA-proteina in eventi fisio/patologici
▼    Biochemical and structural insights on Chromatin Assembly Factor 1 in physio/pathological events Studi biochimici e molecolari sul Fattore di Assemblaggio della Cromatina 1 coinvolta in eventi fisiopatologici
▼    Plant polypeptides as natural enhancers of biostimulation Polipeptidi vegetali come potenziatori naturali della biostimolazione
▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools Modifiche chimiche eseguite su molecole naturali, quali peptide e polisaccaridi, e loro impiego come agenti terapeutici e sonde diagnostiche
▼    Protein-based biotherapeutics Bioterapeutici a base di proteine
▼    Understanding SARS-CoV-2 interaction with its host of for therapeutic applications Studi di interazioni patogeno-ospite in SARS-CoV-2
▼    Structure and function of proteins involved in physio-pathologic processes Struttura e funzione di proteine coinvolte in processi fisiopatologici
▼    Carbonic Anhydrase IX as target for the development of new anti-tumour drugs L’Anidrasi Carbonica IX come target per lo sviluppo di nuovi farmaci antitumorali
▼    Biomolecole in grado di modulare l’angiogenesi VEGF-dipendente Biomolecules able to modulate the VEGF-dependent angiogenesis
▼    A multi-targeting approach to fight COVID-19 Un approccio multi-targeting per combattere COVID-19
▼    Galectins: Structure, function and therapeutic potential inhibitors Galectine: struttura, funzione e potenziali inibitori terapeutici
▼    Caratterizzazione della famiglia proteica delle KCTD: fattori chiave in diversi processi biologici Characterization of the KCTD protein family: key factors in several biological processes
▼    Sintesi chimica e modificazione di proteine per applicazioni in campo biomedico Chemical protein synthesis and modification for biomedical applications
▼    Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives Relazione tra malattia e alterate interazioni proteina-proteina: patogenicità e prospettive terapeutiche
▼    Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications Risonanza magnetica nucleare biomolecolare: studi strutturali di proteine e peptidi e applicazioni per il “drug discovery”
▼    Structural characterization of the porphyrins/proteasome interaction Caratterizzazione strutturale dell’interazione porfirine/proteosoma
▼    Axl and Gas6 targeting for therapeutic and diagnostic applications Molecole che bersagliano Axl e Gas6 per applicazioni a scopo terapeutico e diagnostico
▼    Drug discovery by mirror-image phage display Drug discovery attraverso l’impiego della tecnologia del mirror-image phage display
▼    Analysis of Sam domain druggability through computational and experimental studies I domini Sam come bersagli farmacologici: studi computazionali e sperimentali
▼    Targeting Sam-Sam interactions mediated by EphA2 receptor: design and evaluation of peptide inhibitors Progettazione e validazione di peptidi inibitori delle interazioni Sam-Sam mediate dal recettore EphA2
▼    Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural product in biomedicine. Nucleic acid and protein binding studies Sintesi di small molecules, peptidi modificati e peptidi decorati con nucleobasi. Valutazione spettroscopica e computazionale del potenziale di prodotti naturali in biomedicina. Studi di interazione molecolare con acidi nucleici e proteine
▼    Biochemical and functional characterization of intrinsically disordered proteins (IDPs) in human diseases Caratterizzazione biochimica e funzionale di proteine intrinsecamente disordinate e loro ruolo nelle malattie umane
▼    Biochemical and functional characterization of Protein-Protein and DNA-protein Interaction networks in physio/pathological events Caratterizzazione biochimica e funzionale di interazioni proteina-proteina e DNA-proteina in eventi fisio/patologici
▼    Biochemical and structural insights on Chromatin Assembly Factor 1 in physio/pathological events Studi biochimici e molecolari sul Fattore di Assemblaggio della Cromatina 1 coinvolta in eventi fisiopatologici
▼    Targeting Of Protein-Protein Interactions For Therapeutic Purposes Targeting delle interazioni proteina-proteina per scopi terapeutici
▼    Small molecules and peptides/modified peptides for diagnostic, therapeutic and biotechnological applications Piccole molecole e peptidi/peptidi modificati per applicazioni diagnostiche, terapeutiche e biotecnologiche
▼    Biomolecole in grado di modulare l’angiogenesi VEGF-dipendente Biomolecules able to modulate the VEGF-dependent angiogenesis
▼    New peptide–based molecules as NGF mimetics in the therapy of neurological dysfunctions Nuove molecole di natura peptidica che mimano l’NGF per la terapia di malattie neurologiche
▼    Peptide-based molecules for αvβ3 integrin modulation in Th17 cells-dependent demyelinating diseases Molecole di natura peptidica per modulare l’attività dell’integrina αvβ3 nelle malattie demielinizzanti Th17 dipendenti
▼    Development of integrin subtypes selective ligands: from a first rationally designed peptide to a wide range of molecules Sviluppo di ligandi selettivi per i sottotipi di integrine: dal primo peptide progettato su base razionale verso un ampio spettro di molecole
▼    Design of New FSHR-Specific Peptides for therapeutic and diagnostic applications Progettazione di nuovi peptidi specifici per il recettore dell’FSH per applicazioni diagnostiche e terapeutiche
▼    New synthetic molecules for active targeting of multifunctional theranostic nanosystems Nuove molecole sintetiche per il trasporto attivo di nanosistemi multifunzionali teranostici
▼    Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications Risonanza magnetica nucleare biomolecolare: studi strutturali di proteine e peptidi e applicazioni per il “drug discovery”
▼    Galectins: Structure, function and therapeutic potential inhibitors Galectine: struttura, funzione e potenziali inibitori terapeutici
▼    Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives Relazione tra malattia e alterate interazioni proteina-proteina: patogenicità e prospettive terapeutiche
▼    A multi-targeting approach to fight COVID-19 Un approccio multi-targeting per combattere COVID-19
▼    Drug discovery by mirror-image phage display Drug discovery attraverso l’impiego della tecnologia del mirror-image phage display
▼    Axl and Gas6 targeting for therapeutic and diagnostic applications Molecole che bersagliano Axl e Gas6 per applicazioni a scopo terapeutico e diagnostico
▼    Peptides of therapeutic interest with antimicrobial and/ or antitumoral activity Peptidi di interesse terapeutico con attività antimicrobica e/o antitumorale
▼    Analysis of Sam domain druggability through computational and experimental studies I domini Sam come bersagli farmacologici: studi computazionali e sperimentali
▼    Targeting Sam-Sam interactions mediated by EphA2 receptor: design and evaluation of peptide inhibitors Progettazione e validazione di peptidi inibitori delle interazioni Sam-Sam mediate dal recettore EphA2
▼    Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural product in biomedicine. Nucleic acid and protein binding studies Sintesi di small molecules, peptidi modificati e peptidi decorati con nucleobasi. Valutazione spettroscopica e computazionale del potenziale di prodotti naturali in biomedicina. Studi di interazione molecolare con acidi nucleici e proteine
▼    Plant polypeptides as natural enhancers of biostimulation Polipeptidi vegetali come potenziatori naturali della biostimolazione
▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools Modifiche chimiche eseguite su molecole naturali, quali peptide e polisaccaridi, e loro impiego come agenti terapeutici e sonde diagnostiche
▼    Design and screening of molecular repertoires as a source for new bioactive compounds Progettazione e screening di repertori molecolari come fonte di nuovi composti bioattivi
▼    Targeting Of Protein-Protein Interactions For Therapeutic Purposes Targeting delle interazioni proteina-proteina per scopi terapeutici
▼    Small molecules and modified peptides as drug delivery systems Piccole molecole e peptidi modificati come sistemi di veicolazione dei farmaci
▼    Other Diseases Altre Malattie
▼    Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions
▼    Characterization of neurotoxic and neuroprotective factors by using computational methodologies
▼    Bioactive peptide-membrane assemblies
No results. Nessun risultato.
▼    Biomolecole in grado di modulare l’angiogenesi VEGF-dipendente Biomolecules able to modulate the VEGF-dependent angiogenesis
▼    Sintesi chimica e modificazione di proteine per applicazioni in campo biomedico Chemical protein synthesis and modification for biomedical applications
▼    Comparison of noninvasive cardiac imaging modalities in patients with myocardial infarction
▼    Structural and functional studies of virulence factors in Mycobacterium tuberculosis infection
▼    Assessment of the cardiac risk and its temporal variation
▼    Carbonic Anhydrase family as target for rational drug design
▼    Evaluation of new molecular probes by preclinical imaging Test e validazione di nuove sonde molecolari mediante imaging preclinico
▼    Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural product in biomedicine. Nucleic acid and protein binding studies Sintesi di small molecules, peptidi modificati e peptidi decorati con nucleobasi. Valutazione spettroscopica e computazionale del potenziale di prodotti naturali in biomedicina. Studi di interazione molecolare con acidi nucleici e proteine
▼    Phenotyping of murine models by preclinical imaging Fenotipizzazione di modelli murini mediante imaging preclinico
▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools Modifiche chimiche eseguite su molecole naturali, quali peptide e polisaccaridi, e loro impiego come agenti terapeutici e sonde diagnostiche
▼    Axl and Gas6 targeting for therapeutic and diagnostic applications Molecole che bersagliano Axl e Gas6 per applicazioni a scopo terapeutico e diagnostico
▼    Drug discovery by mirror-image phage display Drug discovery attraverso l’impiego della tecnologia del mirror-image phage display
▼    Caratterizzazione della famiglia proteica delle KCTD: fattori chiave in diversi processi biologici Characterization of the KCTD protein family: key factors in several biological processes
▼    Galectins: Structure, function and therapeutic potential inhibitors Galectine: struttura, funzione e potenziali inibitori terapeutici
▼    Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives Relazione tra malattia e alterate interazioni proteina-proteina: patogenicità e prospettive terapeutiche
▼    Development of integrin subtypes selective ligands: from a first rationally designed peptide to a wide range of molecules Sviluppo di ligandi selettivi per i sottotipi di integrine: dal primo peptide progettato su base razionale verso un ampio spettro di molecole
▼    A multi-targeting approach to fight COVID-19 Un approccio multi-targeting per combattere COVID-19
▼    Functional characterization of synthetic organic molecules of therapeutic interest Caratterizzazione funzionale di molecole organiche sintetiche di interesse terapeutico
▼    Peptides of therapeutic interest with antimicrobial and/ or antitumoral activity Peptidi di interesse terapeutico con attività antimicrobica e/o antitumorale
▼    Biomolecole in grado di modulare l’angiogenesi VEGF-dipendente Biomolecules able to modulate the VEGF-dependent angiogenesis

Born in Rome on 4th September 1968. 1994, February: Degree in Biological Sciences at the University of Rome "La Sapienza". 1994-95: Post-lauream training at the University of Rome "La Sapienza", Dept. of Cellular Biology and Development. 1995, July: On a fellowship at the University of Rome "La Sapienza", Dept. of Cellular Biology and Development. 1995-99: On a fellowship for a PhD in Biochemistry and Molecular Biology, at University of Naples "Federico II". 2000: Contract at the National Council of Research (Center of Biocrystallography), Naples. 2001: Researcher at the C. N. R., Biostructure and Bioimaging Institute, Naples. The research activities of Dr. Di Gaetano have been focused in the fields of molecular biology, cellular biology and biological chemistry. More recently she was interested in the design and functional characterization of oligonucleotide analogs. She was the project leader of a project funded by regional institutions entitled In vitro and in vivo production of the recombinant amyloidogenic protein ApoA-1 (1-93) by adenoviral expression vectors; analysis of fibrils formation mechanism. She participates (or has participated) in several MIUR projects.

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Publications Pubblicazioni
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* A straightforward synthetic access to symmetrical glycosyl disulfides and biological evaluation thereof (291 views visite)
Adinolfi M, Capasso D, Di Gaetano S, Iadonisi A, Leone L, Pastore A
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2011 Sep 21; 9(18): 6278-6283.
Impact Factor: 3.696
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* Gamma Sulphate Pna (pna S): Highly Selective Dna Binding Molecule Showing Promising Antigene Activity (324 views visite)
Avitabile C, Moggio L, Malgieri G, Capasso D, Di Gaetano S, Saviano M, Pedone C, Romanelli A
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2012 May 7; 7(5): e35774-e35774.
Impact Factor: 3.73
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* Molecular recognition of Cullin3 by KCTDs: Insights from experimental and computational investigations (292 views visite)
Balasco N, Pirone L, Smaldone G, Di Gaetano S, Esposito L, Pedone E, Vitagliano L
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014 Jul; 1844(7): 1289-1298.
Impact Factor: 4.882
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* Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction (194 views visite) (PDF 191 views visite)
Birolo L, Sacchi S, Smaldone G, Molla G, Leo G, Caldinelli L, Pirone L, Eliometri P, Di Gaetano S, Orefice I, Pedone E, Pucci P, Pollegioni L
Febs J (ISSN: 1742-464x), 2016 Sep; 283(18): 3353-3370.
Impact Factor: 3.902
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* A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 beta-like: from in silico identification to experimental evidence (277 views visite)
Bosso A, Pirone L, Gaglione R, Pane K, Del Gatto A, Zaccaro L, Di Gaetano S, Diana D, Fattorusso R, Pedone E, Cafaro V, Haagsman HP, Van Dijk A, Scheenstra MR, Zanfardino A, Crescenzi O, Arciello A, Varcamonti M, Veldhuizen EJA, Di Donato A, Notomista E, Pizzo E
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2017 Apr 25; N/D: N/D-N/D.
Impact Factor: 4.28
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* Antiproliferative Activity of Mycalin A and Its Analogues on Human Skin Melanoma and Human Cervical Cancer Cells (15 views visite)
Capasso D, Borbone N, Terracciano M, Di Gaetano S, Piccialli V
Mar Drugs (ISSN: 1660-3397linking), 2020 Jul 29; 18(8): N/D-N/D.
Impact Factor: 4.379
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* Rgdechi-Hcit: Alpha V Beta 3 Selective Pro-Apoptotic Peptide As Potential Carrier For Drug Delivery Into Melanoma Metastatic Cells (369 views visite)
Capasso D, De Paola I, Liguoro A, Del Gatto A, Di Gaetano S, Guarnieri D, Saviano M, Zaccaro L
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2014 Sep 23; 9(9): e106441-e106441.
Impact Factor: 3.234
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* Selective Targeting of αvβ5 Integrin in HepG2 Cell Line by RGDechi15D Peptide (28 views visite)
Capasso D, Del Gatto A, Comegna D, Russo L, Fattorusso R, Saviano M, Di Gaetano S, Zaccaro L
Molecules (ISSN: 1420-3049linking), 2020 Sep 19; 25(18): N/D-N/D.
Impact Factor: 3.267
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* Unveiling a VEGF-mimetic peptide sequence in the IQGAP1 protein (273 views visite)
Capasso D, Di Gaetano S, Celentano V, Diana D, Festa L, Di Stasi R, De Rosa L, Fattorusso R, D'Andrea LD
Mol Biosyst (ISSN: 1742-206x), 2017 Jul 25; 13(8): 1619-1629.
Impact Factor: 2.759
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* Chemical Modification for Proteolytic Stabilization of the Selective alphavbeta3 Integrin RGDechi Peptide: in Vitro and in Vivo Activities on Malignant Melanoma Cells (832 views visite) (PDF 183 views visite)
Comegna D, Zannetti A, Del Gatto A, De Paola I, Russo L, Di Gaetano S, Liguoro A, Capasso D, Saviano M, Zaccaro L
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2017 Dec 14; 60(23): 9874-9884.
Impact Factor: 6.253
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* A biophysical characterization of the folded domains of KCTD12: insights into interaction with the GABA(B2) receptor (260 views visite)
Correale S, Esposito C, Pirone L, Vitagliano L, Di Gaetano S, Pedone E
Journal Of Molecular Recognition (ISSN: 0952-3499, 0952-2349), 2013 Oct; 26(10): 488-495.
Impact Factor: 2.337
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* Molecular organization of the cullin E3 ligase adaptor KCTD11 (348 views visite)
Correale S, Pirone L, Di Marcotullio L, De Smaele E, Greco A, Mazzà D, Moretti M, Alterio V, Vitagliano L, Di Gaetano S, Gulino A, Pedone E
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2011 Apr; 93(4): 715-724.
Impact Factor: 3.022
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* Probing the DNA Reactivity and the Anticancer Properties of a Novel Tubercidin-Pt(II) Complex (81 views visite)
D’errico S, Falanga AP, Capasso D, Di Gaetano S, Marzano M, Terracciano M, Roviello GN, Piccialli G, Oliviero G, Borbone N
Pharmaceutics (ISSN: 1999-4923linking), 2020 Jul 4; 12(7): 627-627.
Impact Factor: 4.421
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* Cullin3 - BTB interface: A novel target for stapled peptides (446 views visite) (PDF 26 views visite)
De Paola I, Pirone L, Palmieri M, Balasco N, Esposito L, Russo L, Mazza D, Di Marcotullio L, Di Gaetano S, Malgieri G, Vitagliano L, Pedone E, Zaccaro L
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2015 Apr 7; 10(4): e0121149-e0121149.
Impact Factor: 3.057
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* Synthesis of diglycosylated (di)sulfides and comparative evaluation of their antiproliferative effect against tumor cell lines: A focus on the nature of sugar-recognizing mediators involved (72 views visite)
Di Gaetano S, Bedini E, Landolfi A, Pedone E, Pirone L, Saviano M, Traboni S, Capasso D, Iadonisi A
Carbohydr Res (ISSN: 0008-6215linking), 2019 Aug 1; 482: 107740-107740.
Impact Factor: 1.91
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* A selective αvβ5 integrin antagonist hidden into the anophelin family protein cE5 from the malaria vector Anopheles gambiae (174 views visite)
Di Gaetano S, Del Gatto A, Pirone L, Comegna D, Zaccaro L, Saviano M, Arcà B, Capasso D, Pedone E
Peptide Science, 2018; N/D: N/D-N/D.
Impact Factor: 2.081
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* Recombinant amyloidogenic domain of ApoA-I: analysis of its fibrillogenic potential (302 views visite)
Di Gaetano S, Guglielmi F, Arciello A, Mangione P, Monti M, Pagnozzi D, Raimondi S, Giorgetti S, Orru S, Canale C, Pucci P, Dobson CM, Bellotti V, Piccoli R
Biochemical And Biophysical Research Communications (ISSN: 0006-291x, 0006-291xprint), 2006 Dec 8; 351(1): 223-228.
Impact Factor: 2.855
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* VEGFR Recognition Interface of a Proangiogenic VEGF-Mimetic Peptide Determined In Vitro and in the Presence of Endothelial Cells by NMR Spectroscopy (268 views visite)
Di Stasi R, Diana D, Capasso D, Di Gaetano S, De Rosa L, Celentano V, Isernia C, Fattorusso R, D'Andrea LD
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2018; 24(44): 11461-11466.
Impact Factor: 5.16
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* Functional Binding Surface Of A Beta-Hairpin Vegf Receptor Targeting Peptide Determined By Nmr Spectroscopy In Living Cells (374 views visite)
Diana D, Russomanno A, De Rosa L, Di Stasi R, Capasso D, Di Gaetano S, Romanelli A, Russo L, D'Andrea LD, Fattorusso R
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Jan 2; 21(1): 91-95.
Impact Factor: 5.771
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* Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates (282 views visite)
Diana D, Smaldone G, De Antonellis P, Pirone L, Carotenuto M, Alonzi A, Di Gaetano S, Zollo M, Pedone E, Fattorusso R
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Sep 9; 19(37): 12217-12220.
Impact Factor: 5.696
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* A Combined NMR and Computational Approach to Determine the RGDechi-hCit-alphav beta3 Integrin Recognition Mode in Isolated Cell Membranes (356 views visite)
Farina B, De Paola I, Russo L, Capasso D, Liguoro A, Gatto AD, Saviano M, Pedone PV, Di Gaetano S, Malgieri G, Zaccaro L, Fattorusso R
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Jan 11; 22(2): 681-693.
Impact Factor: 5.317
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* Conformational studies of RGDechi peptide by natural-abundance NMR spectroscopy (186 views visite)
Farina B, Del Gatto A, Comegna D, Di Gaetano S, Capasso D, Isernia C, Saviano M, Fattorusso R, Zaccaro L, Russo L
J Pept Sci (ISSN: 1075-2617linking, 1099-1387electronic), 2019 May; 25(5): e3166-e3166.
Impact Factor: 1.807
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* Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis (440 views visite)
Finetti F, Basile A, Capasso D, Di Gaetano S, Di Stasi R, Pascale M, Turco CM, Ziche M, Morbidelli L, D'Andrea LD
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2012 Sep 1; 84(3): 303-311.
Impact Factor: 4.576
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* A new biologically active molecular scaffold: crystal structure of 7-(3-hydroxyphenyl)-4-methyl-2H-[1, 2, 4]triazolo[3, 2-c][1, 2, 4]triazole and selective antiproliferative activity of three isomeric triazolo-triazoles (57 views visite)
Fusco S, Capasso D, Centore R, Di Gaetano S, Parisi E
Acta Crystallogr C Struct Chem (ISSN: 2053-2296linking), 2019 Oct 1; 75(Pt10): 1398-1404.
Impact Factor: 0.93
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* Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant (295 views visite)
Merlino A, Avella G, Di Gaetano S, Arciello A, Piccoli R, Mazzarella L, Sica F
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic, 0961-8368linking), 2009 Jan; 18(1): 50-57.
Impact Factor: 2.937
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* Apolipoprotein A-I amyloidogenic variant L174S, expressed and isolated from stably transfected mammalian cells, is associated with fatty acids (229 views visite)
Monti DM(1), Di Gaetano S, Del Giudice R, Giangrande C, Amoresano A, Monti M, Arciello A, Piccoli R
Amyloid (ISSN: 1350-6129), 2012 Mar; 19(1): 21-27.
Impact Factor: 4.436
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* Benzodifuran derivatives as potential antiproliferative agents: possible correlation between the bioactivity and their aggregation properties (412 views visite)
Musumeci D, Roviello GN, Rigione G, Capasso D, Di Gaetano S, Riccardi C, Roviello V, Montesarchio D
Chempluschem, 2017; 82: 251-260.
Impact Factor: 2.8
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* Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives (15 views visite)
Ogloblina AM, Iaccarino N, Capasso D, Di Gaetano S, Garzarella EU, Dolinnaya NG, Yakubovskaya MG, Pagano B, Amato J, Randazzo A
Int J Mol Sci (ISSN: 1422-0067linking), 2020 Oct 21; 21(20): N/D-N/D.
Impact Factor: 4.556
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* A new cryptic cationic antimicrobial peptide from human apolipoprotein E with antibacterial activity and immunomodulatory effects on human cells (370 views visite)
Pane K, Sgambati V, Zanfardino A, Smaldone G, Cafaro V, Angrisano T, Pedone E, Di Gaetano S, Capasso D, Haney EF, Izzo V, Varcamonti M, Notomista E, Hancock RE, Di Donato A, Pizzo E
Febs J (ISSN: 1742-464x), 2016; N/D: N/D-N/D.
Impact Factor: 3.902
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* Tautomeric and conformational switching in a new versatile N-rich heterocyclic ligand (11 views visite)
Parisi E, Capasso D, Capobianco A, Peluso A, Di Gaetano S, Fusco S, Manfredi C, Mozzillo R, Pinto G, Centore R
Dalton Trans (ISSN: 1477-9226linking), 2020 Oct 27; 49(41): 14452-14462.
Impact Factor: 4.174
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* Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2, 1-i]purine Derivatives (50 views visite)
Pelliccia S, Amato J, Capasso D, Di Gaetano S, Massarotti A, Piccolo M, Irace C, Tron GC, Pagano B, Randazzo A, Novellino E, Giustiniano M
J Med Chem (ISSN: 0022-2623linking), 2020 Mar 12; 63(5): 2035-2050.
Impact Factor: 6.205
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* Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation (238 views visite) (PDF 31 views visite)
Pirone L, Caldinelli L, Di Lascio S, Di Girolamo R, Di Gaetano S, Fornasari D, Pollegioni L, Benfante R, Pedone E
Febs J (ISSN: 1742-464xlinking), 2019 Apr 7; 286(13): 2505-2521.
Impact Factor: 3.129
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* Design, synthesis and characterization of a peptide able to bind proteins of the KCTD family: implications for KCTD - cullin 3 recognition (325 views visite)
Pirone L, Correale S, De Paola I, Zaccaro L, De Simone G, Vitagliano L, Pedone E, Di Gaetano S
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 May; 17(5): 373-376.
Impact Factor: 1.799
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* A Multi-Targeting Approach to Fight SARS-CoV-2 Attachment (356 views visite) (PDF 57 views visite)
Pirone L, Del Gatto A, Di Gaetano S, Saviano M, Capasso D, Zaccaro L, Pedone E
Front Mol Biosci (ISSN: 2296-889xlinking), 2020 Aug 3; 7: 186-186.
Impact Factor: 4.188
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* Focusing on the functional characterization of the anserinase from Oreochromis niloticus (136 views visite)
Pirone L, Di Gaetano S, Rizzarelli E, Bellia F, Pedone E
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2019 Feb 22; 130: 158-165.
Impact Factor: 4.784
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* Thermal and chemical stability of two homologous POZ/BTB domains of KCTD proteins characterized by a different oligomeric organization (392 views visite)
Pirone L, Esposito C, Correale S, Graziano G, Di Gaetano S, Vitagliano L, Pedone E
Biomed Res Int (ISSN: 2314-6133, 2314-6141, 2314-6141electronic), 2013; 2013: 162674-162674.
Impact Factor: 1.579
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* Proteins involved in sleep homeostasis: Biophysical characterization of INC and its partners (263 views visite) (PDF 173 views visite)
Pirone L, Smaldone G, Esposito C, Balasco N, Petoukhov MV, Spilotros A, Svergun DI, Di Gaetano S, Vitagliano L, Pedone E
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2016 Sep 24; 131: 106-114.
Impact Factor: 3.112
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* KCTD1: A novel modulator of adipogenesis through the interaction with the transcription factor AP2alpha (121 views visite)
Pirone L, Smaldone G, Spinelli R, Barberisi M, Beguinot F, Vitagliano L, Miele C, Di Gaetano S, Raciti GA, Pedone E
Biochim Biophys Acta Mol Cell Biol Lipids (ISSN: 1388-1981linking), 2019 Aug 26; 1864(12): 158514-158514.
Impact Factor: 4.402
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* Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I (395 views visite)
Raimondi S, Guglielmi F, Giorgetti S, Di Gaetano S, Arciello A, Monti DM, Relini A, Nichino D, Doglia SM, Natalello A, Pucci P, Mangione P, Obici L, Merlini G, Stoppini M, Robustelli P, Tartaglia GG, Vendruscolo M, Dobson CM, Piccoli R, Bellotti V
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2011 Apr 1; 407(3): 465-476.
Impact Factor: 4.001
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* Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes (90 views visite)
Riccardi C, Capasso D, Coppola A, Platella C, Montesarchio D, Di Gaetano S, Roviello GN, Musumeci D
Pharmaceuticals (ISSN: 1424-8247linking), 2020 Sep 30; 13(10): 284-284.
Impact Factor: 4.421
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* Synthesis, DNA binding studies, and antiproliferative activity of novel Pt(II)- complexes with an L-alanyl-based ligand (196 views visite)
Riccardi C, Capasso D, Rozza GM, Platella C, Montesarchio D, Di Gaetano S, Marzo T, Pratesi A, Messori L, Roviello GN, Musumeci D
J Inorg Biochem (ISSN: 0162-0134linking), 2020 Feb; 203: 110868-110868.
Impact Factor: 3.224
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* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (364 views visite)
Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
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* Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (321 views visite)
Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 May; 38(5): 1489-1496.
Impact Factor: 4.106
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* RNA-binding and viral reverse transcriptase inhibitory activity of a novel cationic diamino acid-based peptide (373 views visite)
Roviello GN, Di Gaetano S, Capasso D, Franco S, Crescenzo C, Bucci EM, Pedone C
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2011 Apr 14; 54(7): 2095-2101.
Impact Factor: 5.248
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* Alternate dab-aegPNAs: synthesis, nucleic acid binding studies and biological activity (384 views visite)
Roviello GN, Musumeci D, De Cristofaro A, Capasso D, Di Gaetano S, Bucci EM, Pedone C
Mol Biosyst (ISSN: 1742-2051, 1742-206x, 1742-2051electronic), 2010 Jan; 6(1): 199-205.
Impact Factor: 3.825
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* Synthesis and supramolecular assembly of 1, 3-bis(1 '-uracilyl)-2-propanone (315 views visite)
Roviello GN, Roviello GN, Musumeci D, Capasso D, Di Gaetano S, Costanzo M, Pedone C
Rsc Adv (ISSN: 2046-2069), 2014; 4(54): 28691-28698.
Impact Factor: 3.84
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* Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide (324 views visite)
Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
Rsc Adv (ISSN: 2046-2069), 2016; 6(17): 14140-14148.
Impact Factor: 3.108
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* Deciphering RGDechi peptide‐α5β1 integrin interaction mode in isolated cell membranes (190 views visite)
Russo L, Farina B, Del Gatto A, Comegna D, Di Gaetano S, Capasso D, Liguoro D, Malgieri G, Saviano M, Fattorusso R, Zaccaro L
Peptide Science, 2018; N/D: N/D-N/D.
Impact Factor: 2.081
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* Molecular basis of the scalp-ear-nipple syndrome unraveled by the characterization of disease-causing KCTD1 mutants (92 views visite)
Smaldone G, Balasco N, Pirone L, Caruso D, Di Gaetano S, Pedone EM, Vitagliano L
Sci Rep (ISSN: 2045-2322linking), 2019 Jul 19; 9(1): 10519-10519.
Impact Factor: 5.078
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* Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes (328 views visite)
Smaldone G, Diana D, Pollegioni L, Di Gaetano S, Fattorusso R, Pedone E
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468), 2015 Feb 18; 589(7): 798-804.
Impact Factor: 3.519
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* gH625 is a viral derived peptide for effective delivery of intrinsically disordered proteins (365 views visite)
Smaldone G, Falanga A, Capasso D, Guarnieri D, Correale S, Galdiero M, Netti PA, Zollo M, Galdiero S, Di Gaetano S, Pedone E
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1178-2013electronic), 2013; 8: 2555-2565.
Impact Factor: 4.195
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* Cullin 3 recognition is not a universal property among KCTD proteins (370 views visite)
Smaldone G, Pirone L, Balasco N, Di Gaetano S, Pedone E, Vitagliano L
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2015 May 14; 10(5): e0126808-e0126808.
Impact Factor: 3.057
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* The essential player in adipogenesis GRP78 is a novel KCTD15 interactor (201 views visite)
Smaldone G, Pirone L, Capolupo A, Vitagliano L, Monti MC, Di Gaetano S, Pedone E
Int J Biol Macromol (ISSN: 1879-0003electronic, 0141-8130linking), 2018 Aug; 115: 469-475.
Impact Factor: 4.784
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* Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis (304 views visite)
Spalletti-cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2003 Jun; 88(6): 2900-2907.
Impact Factor: 5.873
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54 Records (52 excluding Abstracts and Conferences escludendo Abstract e Conferenze).
Total impact factor Impact factor totale: 205.791 (198.827 excluding Abstracts and Conferences escludendo Abstract e Conferenze).
Total 5 year impact factor Impact factor a 5 anni totale: 169.427 (161.481 excluding Abstracts and Conferences escludendo Abstract e Conferenze).


Last modified by UNKNOWN on Ultima modifica di origine sconosciuta, in data Thursday 11 February 2021, 16:28:30
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