|Indirizzo||Via Mezzocannone 16, 80134 Napoli - Italia|
|Telefono ufficio||+39 081 2534503|
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Dr Galdiero completed her doctorate in Chemistry with the study of peptides chemistry at the University of Naples Federico II in 1998. From 1986 to 1987 she has carried out research activities at the Columbia University of New York, working on the structure of alpha-hemolysin from S. aureus and its interactions with phospholipids under the supervision of Dr. Eric Gouaux. From 1999 she has been Researcher of the Science Faculty of the University of Napoli "Federico II" and Professor of General and Inorganic Chemistry, Stechiometry and Inorganic Chemistry Laboratory for undergraduates students. She is member of Istituto di Biostrutture e Bioimmagini (IBB) of the National Research Council of Italy and of Centro di Competenza in Diagnostica e Farmaceutica Molecolari (CRdC DFM). The main interest of her research activities are focussed on identifying and defining at a molecular level new diagnostic and therapeutic targets; finding new bioactive ligands able to modulate the activity of the identified targets; improving the transport, specificity, biodistribution, toxicity of identified active compounds by the design of new drug delivery molecular systems. The most recent topics of research concern: 1) biological activity of structural components of Gram-negative bacteria surface; 2) analysis of enveloped viruses penetration mechanism; 3) design of novel molecules that may be used as antimicrobials; 3) design of vaccines; 4) intracellular delivery. Dr Galdiero is author of more than 45 articles on international peer-reviewed journals.