|Name Nome||Laura Zaccaro|
|Area||Research&Development Ricerca e Sviluppo|
|Position Qualifica||Researcher Ricercatore|
|Work site Sede||Naples-Mezzocannone Napoli-Mezzocannone|
|Address Indirizzo||Via Mezzocannone 16, 80134 Naples - Italy Napoli - Italia|
|Office phone Telefono ufficio||+39 081 2534566|
|▼ Cancer Diseases Malattie Neoplastiche|
▼ Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions
▼ Characterization of the KCTD protein family: key factors in several biological processes
▼ Characterization of neurotoxic and neuroprotective factors by using computational methodologies
▼ Targeted Drug Delivery by integrin avb3 antagonist
▼ Protein aggregation and cytotoxicity: molecular, in vitro and in vivo biological studies
No results. Nessun risultato.
▼ Metals and small molecules in the regulation of the Ubiquitin Proteasome Pathway
No results. Nessun risultato.
▼ Peptide modulators of the VEGF-dependent angiogenesis
▼ CA IX as target for the development of new anti-tumour drugs
▼ Carbonic Anhydrase family as target for rational drug design
▼ Clinical Oncology
▼ Translational Molecular Imaging in Cancer
▼ Molecular imaging for personalized therapy in oncology
▼ Modeling radiation induced normal tissue effects
▼ Evaluation of new molecular probes by preclinical imaging. Test e validazione di nuove sonde molecolari mediante imaging preclinico.
▼ Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Nucleic acid and protein binding studies
▼ Brain segmentation for radiation oncology application Segmentazione cerebrale per applicazioni in radiologia oncologica
|▼ Hematologic Diseases Malattie Ematologiche|
|▼ Characterization of the KCTD protein family: key factors in several biological processes|
|▼ Structure-based design of artificial activators that reactivate gene expression in vivo|
|▼ Targeted Drug Delivery by integrin avb3 antagonist|
Born in Naples on 4th May 1968. 1991: Degree in Pharmacy summa cum laude at University of Naples Federico II (Italy). 1994: Postgraduate specialisation summa cum laude in Pharmaceutical Chemistry at University of Naples Federico II. 1992-1995 CNR Fellowships at the Centre of Biocrystallography, Naples. 1995-1996: Fellowship at Department of Chemistry at University of Naples Federico II. 1996-2000: Research assistent at Biotechnology Faculty of University of Naples Federico II. From 2001 to present day: Researcher at Biostructure and Bioimaging Institute-CNR, Naples. 2001-2002: External Scientist at Department of Organic Chemistry, University of Barcelona-Spain. 2004-2005: contract Professor of General Chemistry at Science Faculty of MM. FF. NN-University of Naples Federico II. 2006-2008: Contract Professor of General Chemistry at Biotechnology Faculty of University of Naples Federico II. The scientific interests of Dr. Zaccaro concern both the development of new molecules with specific activities or able to interact with specific molecular targets, and the structure-activity relationship studies of bioactive systems to understand the molecular device for the biological activity. Dr. Zaccaro has experience in the field of rational design of peptide and peptido-mimetic systems, synthesis in solution and on solid phase, purification by chromatography techniques, structural characterisation by mass spectrometry and spectroscopic techniques and interaction studies by surface plasmon resonance.