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Ricerca:      Estesa  
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NomeAlessia Ruggiero
AreaRicerca e Sviluppo
QualificaRicercatore
SedeNapoli - Mezzocannone
IndirizzoVia Mezzocannone 16, 80134 Napoli - Italia
E-mailalessia.ruggierounina.it
Nessuna area di ricerca
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Curriculum vuoto


Contiene: [X]      Estesa  

Autori: [X]   E Tipo di lavoro: [X]

E Data iniziale: Data finale: [X]   E Sede:  E    Affiliazione IBB   [Pulisci modulo]

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* The novel thermostable cellulose-degrading enzyme DtCel5H from Dictyoglomus thermophilum: crystallization and X-ray crystallographic analysis (17 visite)
Squeglia F, Berisio R, Ruggiero A
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xelectronic, 2053-230xlinking), 2018 Jan 1; 74(Pt1): 1-5.
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* A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics (30 visite)
Squeglia F, Ruggiero A, De Simone A, Berisio R
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018; 27: 369-380.
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* Chemistry of Peptidoglycan in Mycobacterium tuberculosis life style: an off-the-wall balance of synthesis and degradation (103 visite) (PDF 61 visite)
Squeglia F, Ruggiero A, Berisio R
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018; 24: 2533-2546.
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* Molecular Scenarios Behind Infectious Diseases (45 visite)
Berisio R, Squeglia F, Ruggiero A
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2017 Nov 24; 24(36): 3939-3941.
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* Structural Versatility of Hepatitis C Virus Proteins: Implications for the Design of Novel Anti-HCV Intervention Strategies (42 visite)
Balasco N, Barone D, Sandomenico A, Ruggiero A, Doti N, Berisio R, Ruvo M, Vitagliano L
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2017 Nov 24; 24(36): 4081-4101.
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* Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis (52 visite)
Ruggiero A, Squeglia F, RomanoM, Vitagliano L, De Simone A, Berisio R
J Biomol Struct Dyn (ISSN: 1538-0254electronic, 0739-1102linking), 2017 May; 35(6): 1322-1330.
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* The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of inflammation (52 visite)
Dennehy R, RomanoM, Ruggiero A, Mohamed YF, Dignam SL, Mujica Troncoso C, Callaghan M, Valvano MA, Berisio R, Mcclean S
Cell Microbiol (ISSN: 1462-5822electronic, 1462-5814linking), 2017 May; 19(5): e12691-e12691.
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* Molecular players in Tuberculosis drug development: another break in the cell wall (78 visite)
Squeglia F, RomanoM, Ruggiero A, Berisio R
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2017 Feb 08; 24: 3954-3969.
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* Molecular mechanisms of defense response induced by chitin oligosaccharides (30 visite)
Berisio R, Ruggiero A, Squeglia F, Esposito C, Molinaro A, Silipo A, Marchetti R, Shibuya N
Research Reports, 2017; N/D: N/D-N/D.
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* Proline 235 plays a key role in the regulation of the oligomeric states of Thermotoga maritima Arginine Binding Protein (44 visite)
Smaldone G, Vigorita M, Ruggiero A, Balasco N, Dattelbaum JD, D'Auria S, Del Vecchio P, Graziano G, Vitagliano L
Biochim Biophys Acta (ISSN: 0006-3002print, 0006-3002linking, 0005-2728), 2016 Jul; 1864(7): 814-824.
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* Generation and characterization of monoclonal antibodies against a cyclic variant of Hepatitis C Virus E2 epitope 412-422 (85 visite) (PDF 61 visite)
Sandomenico A, Leonardi A, Berisio R, Sanguigno L, Foca G, Foca A, Ruggiero A, Doti N, Muscariello L, Barone D, Farina C, Owsianka A, Vitagliano L, Patel AH, Ruvo M
J Virol (ISSN: 1098-5514electronic, 0022-538xlinking), 2016 Jan 27; 90(7): 3745-3759.
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* Peptidoglycan-associated lipoprotein is a virulence factor that is involved in host cell attachment of Burkholderia cepacia complex (38 visite)
Dennehy R, RomanoM, Ruggiero A, Troncoso CM, Fathy Y, Callaghan M, Valvano M, Berisio R, Mcclean S
Cellular Microbiology, 2016; inpress: N/D-N/D.
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* Use of hydrolytic enzymes for algal biomass treatment (86 visite)
Ruggiero A, Squeglia F, Romano M, Berisio R
Current Biotechnology, 2016; 5: 296-304.
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* NMR Structure and Dynamics of the Resuscitation Promoting Factor RpfC Catalytic Domain (86 visite)
Maione V, Ruggiero A, Russo L, De Simone A, Pedone PV, Malgieri G, Berisio R, Isernia C
Plos One (ISSN: 1932-6203electronic, 1932-6203linking), 2015 Nov 17; 10(11): e0142807-e0142807.
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* The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains (77 visite)
Ruggiero A, Squeglia F, Romanò MF, Vitagliano L, De Simone A, Berisio  R
Biochim Biophys Acta (ISSN: 0006-3002print, 0006-3002linking, 0005-2728), 2015 Nov 5; 1860(2): 445-451.
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* A product of RpfB and RipA joint enzymatic action promotes the resuscitation of dormant mycobacteria (77 visite)
Nikitushkin VD, Demina GR, Shleeva MO, Guryanova SV, Ruggiero A, Berisio R, Kaprelyants AS
Febs J (ISSN: 1742-4658electronic, 1742-464xlinking), 2015 Apr 3; 282(13): 2500-2511.
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* Exit from mycobacterial dormancy: a structural perspective (107 visite)
Squeglia F, Ruggiero A, Berisio R
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Feb 9; 22(14): 1698-1709.
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* Differential thermodynamic behaviours of the extra-cellular regions of two Ser/Thr PrkC kinases revealed by calorimetric studies (77 visite)
Berisio R, Squeglia F, Ruggiero A, Petraccone L, Stellato MI, Del Vecchio P
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2015 Feb 8; 1854(5): 402-409.
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* Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: Evidence for the l-to-d inversion of configuration of the catalytic cysteine (81 visite)
Squeglia F, Ruggiero A, Romanò MF, Vitagliano L, Berisio R
Acta Crystallogr Sect D Biol Crystallogr Acta Crystallographica Section D Biological Crystallography (ISSN: 0907-4449), 2014 Sep; 70(9): 2295-2300.
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* Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis (87 visite)
Calvanese L, Falcigno L, Maglione C, Marasco D, Ruggiero A, Squeglia F, Berisio R, D'Auria G
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Jul; 101(7): 712-719.
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* A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima (91 visite)
Ruggiero A, Dattelbaum JD, Staiano M, Berisio R, D'Auria S, Vitagliano L
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2014 May 15; 9(5): e96560-e96560.
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* Temozolomide is an active agent in children with recurrent medulloblastoma/primitive neuroectodermal tumor: An Italian multi-institutional phase II trial (98 visite)
Cefalo G, Massimino M, Ruggiero A, Barone G, Ridola V, Spreafico F, Potepan P, Abate ME, Mascarin M, Garrè ML, Perilongo G, Madon E, Colosimo C, Riccardi R
Neuro Oncology Oxford University Press (ISSN: 1522-8517), 2014 May; 16(5): 748-753.
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* Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization (117 visite)
Hayafune M, Berisio R, Marchetti R, Silipo A, Kayama M, Desaki Y, Arima S, Squeglia F, Ruggiero A, Tokuyasu K, Molinaro A, Kaku H, Shibuya N
Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2014 Jan 21; 111(3): E404-E404.
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* Structures of free and inhibited forms of the L, D-transpeptidase LdtMt1 from Mycobacterium tuberculosis (82 visite)
Correale S, Ruggiero A, Capparelli R, Pedone E, Berisio R
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Sep; 69(Pt9): 1697-1706.
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* Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses (70 visite)
Squeglia F, Romanò MF, Ruggiero A, Vitagliano L, De Simone A, Berisio R
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jun 4; 104(11): 2530-2539.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the l, d-transpeptidase LdtMt1 from Mycobacterium tuberculosis (91 visite)
Correale S, Ruggiero A, Pedone E, Berisio R
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2013 Mar 1; 69(3): 253-256.
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* Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis (65 visite)
Ruggiero A, Marchant J, Squeglia F, Makarov V, De Simone A, Berisio R
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic), 2013 Feb 1; 31(2): 195-205.
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* Role of mutual interactions in the chemical and thermal stability of nucleophosmin NPM1 domains (64 visite)
Marasco D, Ruggiero A, Vascotto C, Poletto M, Scognamiglio PL, Tell G, Vitagliano L
Biochemical And Biophysical Research Communications (ISSN: 0006-291x), 2013 Jan 11; 430(2): 523-528.
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* Bacterial cell division regulation by Ser/Thr kinases: A structural perspective (84 visite)
Ruggiero A, De Simone P, Smaldone G, Squeglia F, Berisio R
Curr Protein Pept Sci (ISSN: 1389-2037), 2012 Dec; 13(8): 756-766.
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* Resuscitation-promoting Factors (Rpf): In Search of Inhibitors (90 visite)
Kaprelyants AS, Mukamolova GV, Ruggiero A, Makarov VA, Demina GR, Shleeva MO, Potapov VD, Shramko PA
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1026-1034.
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* HIV p24 as Scaffold for Presenting Conformational HIV Env Antigens (110 visite)
Tagliamonte M, Marasco D, Ruggiero A, de Stradis A, Tornesello ML, Totrov M, Buonaguro FM, Buonaguro L
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2012 Sep 17; 7(8): N/D-N/D.
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* Enhanced crystallizability by protein engineering approaches: A general overview (1728 visite)
Ruggiero A, Smaldone G, Squeglia F, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2012 Jul; 19(7): 732-742.
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* Structural and enzymatic properties of an in vivo proteolytic form of PD-S2, type 1 ribosome-inactivating protein from seeds of Phytolacca dioica (70 visite)
Di Maro A, Berisio R, Ruggiero A, Tamburino R, Severino V, Zacchia E, Parente A
Biochem Biophys Res Commun (ISSN: 0006-291x), 2012 May 11; 421(3): 514-520.
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* Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability (76 visite)
Esposito L, Ruggiero A, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A, Vitagliano L
Journal Of Structural Biology (ISSN: 1047-8477), 2012 Feb; 177(2): 506-512.
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* Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy (61 visite)
Squeglia F, Marchetti R, Ruggiero A, Lanzetta R, Marasco D, Dworkin J, Petoukhov M, Molinaro A, Berisio R, Silipo A
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2011 Dec 28; 133(51): 20676-20679.
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* Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (83 visite)
Ruggiero A, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS, Berisio R, D'Auria S, Vitagliano L
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2011 Nov 1; 67(11): 1462-1465.
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* X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus (85 visite)
Ruggiero A, Squeglia F, Marasco D, Marchetti R, Molinaro A, Berisio R
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2011 Apr 1; 435(1): 33-41.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (69 visite)
Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
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* Dynamical properties of cold shock protein A from Mycobacterium tuberculosis (70 visite)
D'Auria G, Esposito C, Falcigno L, Calvanese L, Iaccarino E, Ruggiero A, Pedone C, Pedone E, Berisio R
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic), 2010 Nov 26; 402(4): 693-698.
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* Expression, purification, crystallization and preliminary x-ray crystallographic analysis of the peptidoglycan binding region of the ser/thr kinase PrkC from staphylococcus aureus (66 visite)
Ruggiero A, Squeglia F, Izzo V, Silipo A, Vitagliano L, Molinaro A, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2010 Oct; 17(10): 1296-1299.
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* Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (93 visite)
Ruggiero A, Marasco D, Squeglia F, Soldini S, Pedone E, Pedone C, Berisio R
Structurestructure (ISSN: 0969-2126, 1878-4186), 2010 Sep 8; 18(9): 1184-1190.
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* Elongation Factors Efia And Ef-Tu: Their Role In Translation And Beyond (66 visite)
Berisio R, Ruggiero A, Vitagliano L
Israel Journal Of Chemistry, 2010 Jun; 50(1): 71-79.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (61 visite)
Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
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* The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves (63 visite)
Severino V, Chambery A, Di Maro A, Marasco D, Ruggiero A, Berisio R, Giansanti F, Ippoliti R, Parente A
Mol Biosyst (ISSN: 1742-206x), 2010; 6(3): 570-579.
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* Crystal structure of PD-L1, a ribosome inactivating protein from Phytolacca dioica L. leaves with the property to induce DNA cleavage (90 visite)
Ruggiero A, Di Maro A, Severino V, Chambery A, Berisio R
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1135-1142.
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* The dimeric structure of Sulfolobus solfataricus thioredoxin A2 and the basis of its thermostability (63 visite)
Ruggiero A, Masullo M, Marasco D, Ruocco MR, Grimaldi P, Arcari P, Zagari A, Vitagliano L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2009 Dec; 77(4): 1004-1008.
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* Biochemical Characterisation Of The D60a Mutant Of The Elongation Factor 1 Alpha From The Archaeon Sulfolobus Solfataricus (58 visite)
Ruggiero I, Cantiello P, Lamberti A, Sorrentino A, Martucci NM, Ruggiero A, Arcone R, Vitagliano L, Arcari P, Masullo M
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2009 Jul; 91(7): 835-842.
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* Crystallization and preliminary X-ray crystallographic analysis of two dimeric hyperthermostable thioredoxins isolated from Sulfolobus solfataricus (58 visite)
Ruggiero A, Lanzotti MA, Ruocco MR, Grimaldi P, Marasco D, Arcari P, Masullo M, Zagari A, Vitagliano L
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2009 Jun; 65: 604-607.
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* Molecular dynamics studies of the P pilus rod subunit PapA (69 visite)
Vitagliano L, Ruggiero A, Pedone C, Berisio R
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 192-199.
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* Role of side chains in collagen triple helix stabilization and partner recognition (110 visite)
Berisio R, De Simone A, Ruggiero A, Improta R, Vitagliano L
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 131-140.
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* Structure and stability of a thioredoxin reductase from Sulfolobus solfataricus: A thermostable protein with two functions (64 visite)
Ruggiero A, Masullo M, Ruocco MR, Grimaldi P, Lanzotti MA, Arcari P, Zagari A, Vitagliano L
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2009 Mar; 1794(3): 554-562.
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* Crystal Structure of the Resuscitation-Promoting Factor (Delta DUF)RpfB from M. tuberculosis (79 visite)
Ruggiero A, Tizzano B, Pedone E, Pedone C, Wilmanns M, Berisio R
J Mol Biol Journal Of Molecular Biology (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009 Jan 9; 385(1): 153-162.
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* Conformational states and association mechanism of Yersinia pestis Caf1 subunits (61 visite)
Vitagliano L, Ruggiero A, Pedone C, Berisio R
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic), 2008 Sep 8; 372(4): 804-810.
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* Characterisation of the components of the thioredoxin system in the archaeon Sulfolobus solfataricus (71 visite)
Grimaldi P, Ruocco MR, Lanzotti MA, Ruggiero A, Ruggiero I, Arcari P, Vitagliano L, Masullo M
Extremophilesextremophiles (ISSN: 1431-0651, 1433-4909), 2008 Jul; 12(4): 553-562.
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* Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis (61 visite)
Esposito C, Pethoukov MV, Svergun DI, Ruggiero A, Pedone C, Pedone E, Berisio R
J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530), 2008 Jul; 190(13): 4749-4753.
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* Atomic Resolution (1. 1 Angstrom) Structure Of The Ribosome-Inactivating Protein Pd-L4 From Phytolacca Dioica L. Leaves (78 visite)
Ruggiero A, Chambery A, Di Maro A, Parente A, Berisio R
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2008 Apr; 71(1): 8-15.
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* Stability Against Temperature Of Sulfolobus Solfataricus Elongation Factor 1 Alpha, A Multi-Domain Protein (61 visite)
Granata V, Graziano G, Ruggiero A, Raimo G, Masullo M, Arcari P, Vitagliano L, Zagari A
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2008 Apr; 1784(4): 573-581.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (51 visite)
Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
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* A Molecular Dynamics Study of Pilus Subunits: Insights into Pilus Biogenesis (87 visite)
Vitagliano L, Ruggiero A, Pedone C, Berisio R
J Mol Biol Journal Of Molecular Biology (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2007 Apr 6; 367(4): 935-941.
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* Crystallization and preliminary X-ray diffraction analysis of PD-L1, a highly glycosylated ribosome inactivating protein with DNase activity (49 visite)
Ruggiero A, Chambery A, Di Maro A, Mastroianni A, Parente A, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2007; 14(4): 407-409.
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* Crystallization and preliminary x-ray diffraction analysis of PD-L4, a ribosome inactivating protein from Phytolacca dioica L. leaves (91 visite)
Ruggiero A, Chambery A, Di Maro A, Pisante M, Parente A, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2007; 14(1): 97-100.
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* Chemical Denaturation Of The Elongation Factor 1 Alpha Isolated From The Hyperthermophilic Archaeon Sulfolobus Solfataricus (78 visite)
Granata V, Graziano G, Ruggiero A, Raimo G, Masullo M, Arcari P, Vitagliano L, Zagari A
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Jan 24; 45(3): 719-726.
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* Crystallization And Preliminary X-Ray Crystallographic Analysis Of The Sulfolobus Solfataricus Nucleotide-Exchange Factor 1 Beta (50 visite)
Ruggiero A, Masullo M, Arcari P, Raimo G, Vitagliano L, Zagari A
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2005 Nov; 61(11): 1000-1002.
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* Crystallization and preliminary X-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase (51 visite)
Ruggiero A, Ruocco MR, Grimaldi P, Arcari P, Masullo M, Zagari A, Vitagliano L
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2005 Oct; 61: 906-909.
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* The Crystal Structure Of Sulfolobus Solfataricus Elongation Factor 1 Alpha In Complex With Magnesium And Gdp (119 visite)
Vitagliano L, Ruggiero A, Masullo M, Cantiello P, Arcari P, Zagari A
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2004; 43(21): 6630-6636.
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Interrogazione bibliografica effettuata: ([author] RUGGIERO_A)








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