* Crystal structure of the ferric homotetrameric beta4 human hemoglobin (24 visite)
Mazzarella L, Merlino A, Balasco N, Balsamo A, Vergara A
Biophys Chem (ISSN: 0301-4622linking), 2018 Sep; 240: 9-14.
Impact Factor: 1.87
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* Cisplatin Binding Sites in Human H-Chain Ferritin (70 visite)
Ferraro G, Ciambellotti S, Messori L, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x), 2017 Aug 7; 56(15): 9064-9070.
Impact Factor: 4.7
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* A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin (77 visite)
Picone D, Donnarumma F, Ferraro G, Gotte G, Fagagnini A, Butera G, Donadelli M, Merlino A
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2017 Aug; 173: 105-112.
Impact Factor: 3.063
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* Protein Metalation by Anticancer Metallodrugs: A Joint ESI MS and XRD Investigative Strategy (46 visite)
Merlino A, Marzo T, Messori L
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017 May 23; 23(29): 6942-6947.
Impact Factor: 5.16
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* Mitochondria Targeting with Luminescent Rhenium(I) Complexes (78 visite)
Skiba J, Bernas T, Trzybinski D, Wozniak K, Ferraro G, Marasco D, Merlino A, Shafikov MZ, Czerwieniec R, Kowalski K
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2017 May 15; 22(5): N/D-N/D.
Impact Factor: 3.098
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* X-ray Structure of the Carboplatin-Loaded Apo-Ferritin Nanocage (57 visite)
Pontillo N, Ferraro G, Helliwell JR, Amoresano A, Merlino A
Acs Med Chem Lett (ISSN: 1948-5875), 2017 Feb 28; 8(4): 433-437.
Impact Factor: 3.794
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* {Ru(CO)x}-Core complexes with benzimidazole ligands: synthesis, X-ray structure and evaluation of anticancer activity in vivo (100 visite)
Tamasi G, Merlino A, Scaletti F, Heffeter P, Legin AA, Jakupec MA, Berger W, Messori L, Keppler BK, Cini R
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9226linking), 2017 Feb 28; 46(9): 3025-3040.
Impact Factor: 4.099
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* Fine Sampling of the R--> T Quaternary-Structure Transition of a Tetrameric Hemoglobin (107 visite)
Vitagliano L, Mazzarella L, Merlino A, Vergara A
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017 Jan 12; 23(3): 605-613.
Impact Factor: 5.16
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* Cisplatin binding to proteins: A structural perspective (140 visite)
Messori L, Merlino A
Coord Chem Rev (ISSN: 0010-8545), 2016; 315: 67-89.
Impact Factor: 13.324
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* Cisplatin encapsulation within a ferritin nanocage: A high-resolution crystallographic study (102 visite)
Pontillo N, Pane F, Messori L, Amoresano A, Merlino A
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2016; 52(22): 4136-4139.
Impact Factor: 6.319
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* Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme (83 visite)
Ferraro G, Pica A, Russo Krauss I, Pane F, Amoresano A, Merlino A
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2016; N/D: 1-10.
Impact Factor: 2.894
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* Protein conformational perturbations in hereditary amyloidosis: Differential impact of single point mutations in ApoAI amyloidogenic variants (149 visite)
Del Giudice R, Arciello A, Itri F, Merlino A, Monti M, Buonanno M, Penco A, Canetti D, Petruk G, Monti SM, Relini A, Pucci P, Piccoli R, Monti DM
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2016; 1860(2): 434-444.
Impact Factor: 5.476
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* The maturation mechanism of γ-glutamyl transpeptidases: Insights from the crystal structure of a precursor mimic of the enzyme from Bacillus licheniformis and from site-directed mutagenesis studies (108 visite)
Pica A, Chi M-C, Chen Y-Y, D'Ischia M, Lin L-L, Merlino A
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2016; 1864(2): 195-203.
Impact Factor: 5.476
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* Cisplatin binding to human serum albumin: A structural study (172 visite)
Ferraro G, Massai L, Messori L, Merlino A
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2015; 51(46): 9436-9439.
Impact Factor: 6.567
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* Fusion of raft-like lipid bilayers operated by a membranotropic domain of the HSV-type I glycoprotein gH occurs through a cholesterol-dependent mechanism (153 visite)
Vitiello G, Falanga A, Petruk AA, Merlino A, Fragneto G, Paduano L, Galdiero S, D'Errico G
Soft Matter (ISSN: 1744-683x), 2015; 11(15): 3003-3016.
Impact Factor: 3.798
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* Interaction of anticancer Ru(III) complexes with single stranded and duplex DNA model systems (139 visite)
Musumeci D, Rozza L, Merlino A, Paduano L, Marzo T, Massai L, Messori L, Montesarchio D
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9226linking), 2015; 44(31): 13914-13925.
Impact Factor: 4.177
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* Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts (104 visite)
Messori L, Marzo T, Merlino A
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; N/D: N/D-N/D.
Impact Factor: 3.205
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* α-thalassemia associated with Hb instability: A tale of two features. The case of Hb Rogliano or α1 Cod 108(G15)Thr→Asn and Hb Policoro or α2 Cod 124(H7)Ser→Pro (161 visite)
Bisconte MG, Caldora M, Musollino G, Cardiero G, Flagiello A, La Porta G, Lagona L, Prezioso R, Qualtieri G, Gaudiano C, Medulla E, Merlino A, Pucci P, Lacerra G
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2015; 10(3): N/D-N/D.
Impact Factor: 3.057
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* Missing gold atoms in lysozyme crystals used to grow gold nanoparticles (126 visite)
Merlino A, Caterino M, Russo Krauss I, Vergara A
Nat Nanotechnol (ISSN: 1748-3387), 2015; 10(4): 285-285.
Impact Factor: 35.267
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* Oxaliplatin vs. cisplatin: Competition experiments on their binding to lysozyme (92 visite)
Marasco D, Messori L, Marzo T, Merlino A
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9226linking), 2015; 44(22): 10392-10398.
Impact Factor: 4.177
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* Platinated oligomers of bovine pancreatic ribonuclease: Structure and stability (158 visite)
Picone D, Donnarumma F, Ferraro G, Russo Krauss I, Fagagnini A, Gotte G, Merlino A
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; 146: 37-43.
Impact Factor: 3.205
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* Platinum(II) Complexes with O, S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding (106 visite)
Mügge C, Marzo T, Massai L, Hildebrandt J, Ferraro G, Rivera-Fuentes P, Metzler-Nolte N, Merlino A, Messori L, Weigand W
Inorg Chem (ISSN: 0020-1669, 1520-510x), 2015; 54(17): 8560-8570.
Impact Factor: 4.82
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* Structural evidences for a secondary gold binding site in the hydrophobic box of lysozyme (133 visite)
Ferraro G, Massai L, Messori L, Cinellu MA, Merlino A
Biometals (ISSN: 0966-0844), 2015; 28(4): 745-754.
Impact Factor: 2.134
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* The X-ray structure of the primary adducts formed in the reaction between cisplatin and cytochrome (103 visite)
Ferraro G, Messori L, Merlino A
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2015; 51(13): 2559-2561.
Impact Factor: 6.567
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* Interaction between Proteins and Ir Based CO Releasing Molecules: Mechanism of Adduct Formation and CO Release (143 visite)
Petruk AA, Vergara A, Marasco D, Bikiel D, Doctorovich F, Estrin DA, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x), 2014 Oct 6; 53(19): 10456-10462.
Impact Factor: 4.762
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* Protein Recognition of Gold-Based Drugs: 3D Structure of the Complex Formed When Lysozyme Reacts with Aubipy(c) (141 visite)
Messori L, Cinellu MA, Merlino A
Acs Med Chem Lett (ISSN: 1948-5875), 2014 Jul 31; 5(10): 1110-1113.
Impact Factor: 3.12
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* Comments on Structural studies of haemoglobin from pisces species shortfin mako shark (Isurus oxyrinchus) at 1. 9 angstrom resolution by P. Ramesh et al. (2013). J. Synchrotron Rad. 20, 843-847 (130 visite)
Merlino A, Vergara A, Vitagliano L
J Synchrotron Radiat (ISSN: 0909-0495), 2014 Jul; 21: N/D-N/D.
Impact Factor: 2.794
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* Molecular bases of protein halotolerance (145 visite)
Graziano G, Merlino A
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014 Apr; 1844(4): 850-858.
Impact Factor: 4.882
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* Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability (167 visite)
Merlino A, Russo Krauss I, Castellano I, Ruocco MR, Capasso A, De Vendittis E, Rossi B, Sica F
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014 Mar; 1844(3): 632-640.
Impact Factor: 4.882
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* A regular thymine tetrad and a peculiar supramolecular assembly in the first crystal structure of an all-LNA G-quadruplex (134 visite)
Russo Krauss I, Parkinson GN, Merlino A, Mattia CA, Randazzo A, Novellino E, Mazzarella L, Sica F
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2014 Feb; 70(2): 362-370.
Impact Factor: 7.232
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* Reaction of Hg2+ Insertion into Cysteine Pairs Within Bovine Insulin Crystals Followed via Raman Spectroscopy (123 visite)
Caterino M, Merlino A, Balsamo A, Russo Krauss I, Parisi S, Vergara A
J Solution Chem (ISSN: 0095-9782), 2014 Feb; 43(1): 135-143.
Impact Factor: 1.177
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* Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(III) compound (109 visite)
Messori L, Scaletti F, Massai L, Cinellu MA, Russo Krauss I, Di Martino G, Vergara A, Paduano L, Merlino A
Metallomics (ISSN: 1756-5901, 1756-591x), 2014; 6(2): 233-236.
Impact Factor: 3.585
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* Interactions of gold-based drugs with proteins: the structure and stability of the adduct formed in the reaction between lysozyme and the cytotoxic gold(III) compound Auoxo3 (154 visite)
Russo Krauss I, Messori L, Cinellu MA, Marasco D, Sirignano R, Merlino A
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9226linking), 2014; 43(46): 17483-17488.
Impact Factor: 4.197
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* γ-Glutamyl transpeptidase architecture: Effect of extra sequence deletion on autoprocessing, structure and stability of the protein from Bacillus licheniformis (112 visite)
Chi M-C, Lo Y-H, Chen Y-Y, Lin L-L, Merlino A
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014; 1844(12): 2290-2297.
Impact Factor: 4.882
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* Low resolution X-ray structure of γ-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion (126 visite)
Lin L-L, Chen Y-Y, Chi M-C, Merlino A
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014; 1844(9): 1523-1529.
Impact Factor: 4.882
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* Structural modifications induced by the switch from an endogenous bis-histidyl to an exogenous cyanomet hexa-coordination in a tetrameric haemoglobin (127 visite)
Mazzarella L, Merlino A, Vitagliano L, Verde C, Di Prisco G, Peisach J, Vergara A
Rsc Adv (ISSN: 2046-2069), 2014; 4(49): 25852-25856.
Impact Factor: 3.84
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* Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer (170 visite)
Pica A, Russo Krauss I, Merlino A, Nagatoishi S, Sugimoto N, Sica F
Febs Journal (ISSN: 1742-464x), 2013 Dec; 280(24): 6581-6588.
Impact Factor: 3.986
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* Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer (118 visite)
Russo Krauss I, Pica A, Merlino A, Mazzarella L, Sica F
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Dec; 69(12): 2403-2411.
Impact Factor: 7.232
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* The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer (136 visite)
Sica F, Pica A, Merlino A, Russo Krauss I, Ercole C, Picone D
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013 Nov 29; 587(23): 3755-3762.
Impact Factor: 3.341
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The Structure Of The Cd3 Zeta Zeta Transmembrane Dimer In Popc And Raft-Like Lipid Bilayer: A Molecular Dynamics Study (189 visite)
Petruk AA, Varriale S, Coscia MR, Mazzarella L, Merlino A, Oreste U
Bba-Mol Basis Dis (ISSN: 0005-2736, 0006-3002e, 0005-2736print), 2013 Nov; 1828(11): 2637-2645.
Impact Factor: 3.498
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* Investigating the Ruthenium Metalation of Proteins: X-ray Structure and Raman Microspectroscopy of the Complex between RNase A and AziRu (103 visite)
Vergara A, Russo Krauss I, Montesarchio D, Paduano L, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Oct 7; 52(19): 10714-10716.
Impact Factor: 4.794
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* Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase (145 visite)
Pica A, Merlino A, Buell AK, Knowles TJ, Pizzo E, D'Alessio G, Sica F, Mazzarella L
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Oct; 69: 2116-2123.
Impact Factor: 7.232
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* Molecular basis of the NO trans influence in quaternary T-state human hemoglobin: A computational study (116 visite)
Alcides Petruk A, Vergara A, Estrin D, Merlino A
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013 Sep 2; 587(15): 2393-2398.
Impact Factor: 3.341
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Role of tertiary structures on the Root effect in fish hemoglobins (156 visite)
Ronda L, Merlino A, Bettati S, Verde C, Balsamo A, Mazzarella L, Mozzarelli A, Vergara A
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Sep; 1834(9): 1885-1893.
Impact Factor: 3.191
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* A Novel Interdomain Interface In Crystallins: Structural Characterization Of The Beta Gamma-Crystallin From Geodia Cydonium At 0. 99 Angstrom Resolution (198 visite)
Vergara A, Grassi M, Sica F, Pizzo E, D’Alessio G, Mazzarella L, Merlino A
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jun; 69(6): 960-967.
Impact Factor: 7.232
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* An overview of biological macromolecule crystallization (202 visite)
Russo Krauss I, Merlino A, Vergara A, Sica F
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2013 May 31; 14(6): 11643-11691.
Impact Factor: 2.339
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* Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu (129 visite)
Vergara A, D’Errico G, Montesarchio D, Mangiapia G, Paduano L, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Apr 15; 52(8): 4157-4159.
Impact Factor: 4.794
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Effect Of Nacl On The Conformational Stability Of The Thermophilic Gamma-Glutamyltranspeptidase From Geobacillus Thermodenitrificans: Implication For Globular Protein Halotolerance (119 visite)
Pica A, Russo Krauss I, Castellano I, La Cara F, Graziano G, Sica F, Merlino A
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Jan; 1834(1): 149-157.
Impact Factor: 3.191
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* Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study (119 visite)
Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jan; 69: 137-140.
Impact Factor: 7.232
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* Cholesterol modulates the fusogenic activity of a membranotropic domain of the FIV glycoprotein gp36 (122 visite)
Vitiello G, Fragneto G, Petruk AA, Falanga A, Galdiero S, D'Ursi A, Merlino A, D'Errico G
Soft Matter (ISSN: 1744-683x), 2013; 9(28): 6442-6456.
Impact Factor: 4.151
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Duplex-Quadruplex Motifs In A Novel Structural Organization Cooperatively Contribute To Thrombin Binding Of Hd22-27mer (113 visite)
Russo Krauss I, Pica A, Merlino A, Mazzarella L, Sica F
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013; D69: 2403-2411.
Impact Factor: 7.232
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* Heterogeneous nucleation helps the search for initial crystallization conditions of γ-glutamyl transpeptidase from Bacillus licheniformis (105 visite)
Lin LL, Merlino A
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013; 69(6): 669-672.
Impact Factor: 0.568
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Investigating The Ruthenium Metallation Of Proteins: X-Ray Structure And Raman Microspectroscopy Of The Complex Between Rnase A And Aziru (106 visite)
Vergara A, Montesarchio D, Russo Krauss I, Paduano L, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510xe, 1520-510xelectronic), 2013; 52(19): 10714-10716.
Impact Factor: 4.794
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Selective X-Ray Induced No-Photodissociation In Hemoglobin Crystals: Evidence From A Raman Assisted-Crystallographic Study (102 visite)
Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
Acta Cryst D 69, 2013; 1: 137-140.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

* The mode of action of anticancer gold-based drugs: a structural perspective (117 visite)
Messori L, Scaletti F, Massai L, Cinellu MA, Gabbiani C, Vergara A, Merlino A
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2013; 49(86): 10100-10102.
Impact Factor: 6.718
Dettagli    Esporta in BibTeX    Esporta in EndNote

* ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus (113 visite)
Coppola D, Abbruzzetti S, Nicoletti F, Merlino A, Gambacurta A, Giordano D, Howes BD, De Sanctis G, Vitagliano L, Bruno S, di Prisco G, Mazzarella L, Smulevich G, Coletta M, Viappiani C, Vergara A, Verde C
Molecular Biosystems (ISSN: 1742-206x), 2012 Oct 30; 8(12): 3295-3304.
Impact Factor: 3.35
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* High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity (129 visite)
Russo Krauss I, Merlino A, Randazzo A, Novellino E, Mazzarella L, Sica F
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2012 Sep; 40(16): 8119-8128.
Impact Factor: 8.278
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease (104 visite)
Merlino A, Picone D, Ercole C, Balsamo A, Sica F
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 May; 94(5): 1108-1118.
Impact Factor: 3.142
Dettagli    Esporta in BibTeX    Esporta in EndNote

* Exploring The Unfolding Mechanism Of Gamma-Glutamyltranspeptidases: The Case Of The Thermophilic Enzyme From Geobacillus Thermodenitrificans (140 visite)
Pica A, Russo Krauss I, Castellano I, Rossi M, La Cara F, Graziano G, Sica F, Merlino A
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2012 Apr; 1824(4): 571-577.
Impact Factor: 3.733
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* Role of the tertiary and quaternary structure in the formation of bis-histidyl adducts in cold-adapted hemoglobins (126 visite)
Balsamo A, Sannino F, Merlino A, Parrilli E, Tutino ML, Mazzarella L, Vergara A
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 Apr; 94(4): 953-960.
Impact Factor: 3.142
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* Identification of an active dimeric intermediate populated during the unfolding process of the cambialistic superoxide dismutase from Streptococcus mutans (126 visite)
Merlino A, Russo Krauss I, Rossi B, De Vendittis A, Marco S, De Vendittis E, Vergara A, Sica F
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 Mar; 94(3): 768-775.
Impact Factor: 3.142
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* Increasing the X-ray diffraction power of protein crystals by dehydration: the case of bovine serum albumin and a survey of literature data (155 visite)
Russo Krauss I, Sica F, Mattia CA, Merlino A
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2012 Mar; 13(3): 3782-3800.
Impact Factor: 2.464
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* Destabilization of Lipid Membranes by a Peptide Derived from Glycoprotein gp36 of Feline Immunodeficiency Virus: A Combined Molecular Dynamics/Experimental Study (142 visite)
Merlino A, Vitiello G, Grimaldi M, Sica F, Busi E, Basosi R, D’Ursi A, Fragneto G, Paduano L, D’Errico G
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2012 Jan 12; 116(1): 401-412.
Impact Factor: 3.607
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* γ-glutamyltranspeptidases: Sequence, structure, biochemical properties, and biotechnological applications (125 visite)
Castellano I, Merlino A
Cell Mol Life Sci (ISSN: 1420-682x), 2012; 69(20): 3381-3394.
Impact Factor: 5.615
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* Improving Protein Crystal Quality by the Without-Oil Microbatch Method: Crystallization and Preliminary X-ray Diffraction Analysis of Glutathione Synthetase from Pseudoalteromonas haloplanktis (146 visite)
Merlino A, Russo Krauss I, Albino A, Pica A, Vergara A, Masullo M, De Vendittis E, Sica F
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2011 Sep; 12(9): 6312-6319.
Impact Factor: 2.598
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* Occurrence and formation of endogenous histidine hexa-coordination in cold-adapted hemoglobins (111 visite)
Merlino A, Howes BD, Prisco G, Verde C, Smulevich G, Mazzarella L, Vergara A
Iubmb Life (ISSN: 1521-6543, 1521-6551), 2011 May; 63(5): 295-303.
Impact Factor: 3.514
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* A novel ErbB2 epitope targeted by human antitumor immunoagents (136 visite)
Troise F, Monti M, Merlino A, Cozzolino F, Fedele C, Russo Krauss I, Sica F, Pucci P, D'Alessio G, De Lorenzo C
Febs Journal (ISSN: 1742-464x), 2011 Apr; 278(7): 1156-1166.
Impact Factor: 3.79
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* Protonation of Histidine 55 Affects the Oxygen Access to Heme in the Alpha Chain of the Hemoglobin from the Antarctic Fish Trematomus bernacchii (127 visite)
Boechi L, Marti MA, Vergara A, Sica F, Mazzarella L, Estrin DA, Merlino A
Iubmb Life (ISSN: 1521-6543, 1521-6551), 2011 Mar; 63(3): 175-182.
Impact Factor: 3.514
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* A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish (168 visite)
Pizzo E, Merlino A, Turano M, Russo Krauss I, Coscia F, Zanfardino A, Varcamonti M, Furia A, Giancola C, Mazzarella L, Sica F, D'Alessio G
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2011 Jan 15; 433(2): 345-355.
Impact Factor: 4.897
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* Gene cloning and protein expression of γ-glutamyltranspeptidases from Thermus thermophilus and Deinococcus radiodurans: Comparison of molecular and structural properties with mesophilic counterparts (99 visite)
Castellano I, Di Salle A, Merlino A, Rossi M, La Cara F
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic), 2011; 15(2): 259-270.
Impact Factor: 2.941
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* Thrombin-aptamer recognition: a revealed ambiguity (140 visite)
Russo Krauss I, Merlino A, Giancola C, Randazzo A, Mazzarella L, Sica F
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2011; 39(17): 7858-7867.
Impact Factor: 8.026
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* An evolutionary conserved motif is responsible for Immunoglobulin heavy chain packing in the B cell membrane (115 visite)
Varriale S, Merlino A, Coscia MR, Mazzarella L, Oreste U
Molecular Phylogenetics And Evolution (ISSN: 1055-7903), 2010 Dec; 57(3): 1238-1244.
Impact Factor: 3.889
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* Structure and flexibility in cold-adapted iron superoxide dismutases: The case of the enzyme isolated from Pseudoalteromonas haloplanktis (157 visite)
Merlino A, Russo Krauss I, Castellano I, De Vendittis E, Rossi B, Conte M, Vergara A, Sica F
J Struct Biol (ISSN: 1047-8477), 2010 Dec; 172(3): 343-352.
Impact Factor: 3.5
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* Crystallization, preliminary X-ray diffraction studies and Raman microscopy of the major haemoglobin from the sub-Antarctic fish Eleginops maclovinus in the carbomonoxy form (105 visite)
Merlino A, Vitagliano L, Balsamo A, Nicoletti FP, Howes BD, Giordano D, Coppola D, Di Prisco G, Verde C, Smulevich G, Mazzarella L, Vergara A
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2010 Nov; 66: 1536-1540.
Impact Factor: 0.563
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* An Order-Disorder Transition Plays a Role in Switching Off the Root Effect in Fish Hemoglobins (128 visite)
Vergara A, Vitagliano L, Merlino A, Sica F, Marino K, Verde C, di Prisco G, Mazzarella L
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2010 Oct 15; 285(42): 32568-32575.
Impact Factor: 5.328
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* Crystallization and preliminary X-ray analysis of the complex of human alpha-thrombin with a modified thrombin-binding aptamer (136 visite)
Russo Krauss I, Merlino A, Randazzo A, Mazzarella L, Sica F
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309, 1532-2335electronic), 2010 Aug 1; 66(Pt8): 961-963.
Impact Factor: 0.563
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* Free-Energy Profile for CO Binding to Separated Chains of Human and Trematomus newnesi Hemoglobin: Insights from Molecular Dynamics Simulations and Perturbed Matrix Method (127 visite)
Merlino A, Vergara A, Sica F, Aschi M, Amadei A, Di Nola A, Mazzarella L
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 May 27; 114(20): 7002-7008.
Impact Factor: 3.603
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* Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity (219 visite)
Castellano I, Merlino A, Rossi M, La Cara F
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2010 May; 92(5): 464-474.
Impact Factor: 3.787
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* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (113 visite)
Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
Bba-Mol Basis Dis (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
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* Combined Crystallographic and Spectroscopic Analysis of Trematomus bernacchii Hemoglobin Highlights Analogies and Differences in the Peculiar Oxidation Pathway of Antarctic Fish Hemoglobins (141 visite)
Merlino A, Vitagliano L, Howes BD, Verde C, Di Prisco G, Smulevich G, Sica F, Vergara A
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1117-1125.
Impact Factor: 2.605
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* Toward an Antitumor Form of Bovine Pancreatic Ribonuclease: The Crystal Structure of Three Noncovalent Dimeric Mutants (143 visite)
Merlino A, Russo Krauss I, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1029-1037.
Impact Factor: 2.605
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* Correlation between Hemichrome Stability and the Root Effect in Tetrameric Hemoglobins (129 visite)
Vergara A, Franzese M, Merlino A, Bonomi G, Verde C, Giordano D, Di Prisco G, Lee HC, Peisach J, Mazzarella L
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2009 Sep 5; 97(3): 866-874.
Impact Factor: 4.39
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* The bis-histidyl complex in hemoproteins: A detailed conformational analysis of database protein structures and the case of Antarctic fish hemoglobins (152 visite)
Merlino A, Vergara A, Sica F, Mazzarella L
Marine Genomics (ISSN: 1874-7787), 2009 Mar; 2(1): 51-56.
Impact Factor: 1.2
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* Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant (112 visite)
Merlino A, Avella G, Di Gaetano S, Arciello A, Piccoli R, Mazzarella L, Sica F
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic, 0961-8368linking), 2009 Jan; 18(1): 50-57.
Impact Factor: 2.937
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* Structure and dimerization of the teleost transmembrane immunoglobulin region (150 visite)
Merlino A, Varriale S, Coscia MR, Mazzarella L, Oreste U
Journal Of Molecular Graphics & Modelling (ISSN: 1093-3263), 2008 Oct; 27(3): 401-407.
Impact Factor: 2.347
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* Spectroscopic and crystallographic characterization of a tetrameric hemoglobin oxidation reveals structural features of the functional intermediate relaxed/tense state (137 visite)
Vitagliano L, Vergara A, Bonomi G, Merlino A, Verde C, Di Prisco G, Howes BD, Smulevich G, Mazzarella L
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2008 Sep 13; 130(32): 10527-10535.
Impact Factor: 8.091
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* Correlation between Raman and X-ray crystallography data of (Pro-Pro-Gly)(10) (113 visite)
Merlino A, Sica F, Mazzarella L, Zagari A, Vergara A
Biophys Chem (ISSN: 0301-4622, 0301-4622linking), 2008 Sep; 137(1): 24-27.
Impact Factor: 2.362
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* The buried diversity of bovine seminal ribonuclease: Shape and cytotoxicity of the swapped non-covalent form of the enzyme (99 visite)
Merlino A, Ercole C, Picone D, Pizzo E, Mazzarella L, Sica F
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2008 Feb 15; 376(2): 427-437.
Impact Factor: 4.146
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* A novel method for detection of selenomethionine incorporation in protein crystals via Raman microscopy (129 visite)
Vergara A, Merlino A, Pizzo E, D'Alessio G, Mazzarella L
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2008 Feb; 64: 167-171.
Impact Factor: 2.943
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* A Novel Method For Detection Of Se-Met Inclusion Into Protein Crystals Via Raman Microscopy (104 visite)
Vergara A, Merlino A, Pizzo E, D'Alessio G, Mazzarella L
Acta Crystallogr D Biol Crystallogr, 2008; N/D: 167-171.
Impact Factor: 2.069
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* Crystallization and preliminary x-ray diffraction studies of a psychrophilic iron superoxide dismutase from Pseudoalteromonas haloplanktis (94 visite)
Merlino A, Russo Krauss I, Castellano I, De Vendittis E, Vergara A, Sica F
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2008; 15(4): 415-418.
Impact Factor: 1.281
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* Reduction of ferric hemoglobin from Trematomus bernacchii in a partial bis-histidyl state produces a deoxy coordination even when encapsulated into the crystal phase (102 visite)
Merlino A, Verde C, Di Prisco G, Mazzarella L, Vergara A
Spectroscopy An International Journal (ISSN: 0712-4813), 2008; 22(2-3): 143-152.
Impact Factor: 0.82
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* Spectroscopic And Crystallographic Characterization Of A Tetrameric Hemoglobin Oxidation Pathway Reveals Structural Features Of A Functional Intermediate R/T State (120 visite)
Vitagliano L, Vergara A, Bonomi G, Merlino A, Verde C, Di Prisco G, Howes BD, Smulevich G, Mazzarella L
Biophys J, 2008; 94: 4031-4040.
Impact Factor: 3.832
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* Structural characterization of ferric hemoglobins from three Antarctic fish species of the suborder notothenioidei (129 visite)
Vergara A, Franzese M, Merlino A, Vitagliano L, Verde C, Di Prisco G, Lee HC, Peisach J, Mazzarella L
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2007 Oct; 93(8): 2822-2829.
Impact Factor: 4.627
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* Approximate values for force constant and wave number associated with a low-frequency concerted motion in proteins can be evaluated by a comparison of X-ray structures (96 visite)
Merlino A, Sica F, Mazzarella L
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2007 May 17; 111(19): 5483-5486.
Impact Factor: 4.086
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* High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect (124 visite)
Mazzarella L, Vergara A, Vitagliano L, Merlino A, Bonomi G, Scala S, Verde C, Di Prisco G
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Nov 1; 65(2): 490-498.
Impact Factor: 3.73
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* Polyglutamine Repeats And Beta-Helix Structure: Molecular Dynamics Study (199 visite)
Merlino A, Esposito L, Vitagliano L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Jun 1; 63(4): 918-927.
Impact Factor: 3.73
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* Minimal structural requirements for root effect: Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus newnesi (180 visite)
Mazzarella L, Bonomi G, Lubrano MC, Merlino A, Riccio A, Vergara A, Vitagliano L, Verde C, Di Prisco G
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Feb 1; 62(2): 316-321.
Impact Factor: 3.73
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* The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase mutants (149 visite)
Merlino A, Mazzarella L, Carannante A, Di Fiore A, Di Donato A, Notomista E, Sica F
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2005 May 6; 280(18): 17953-17960.
Impact Factor: 5.854
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* Open interface and large quaternary structure movements in 3D domain swapped proteins: Insights from molecular dynamics simulations of the C-terminal swapped dimer of ribonuclease (197 visite)
Merlino A, Ceruso MA, Vitagliano L, Mazzarella L
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2005 Mar; 88(3): 2003-2012.
Impact Factor: 4.507
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* Structural Characterization Of The Oxidation Pathway Of Antarctic Fish Hemoglobins (122 visite)
Vitagliano L, Bonomi G, Franzese M, Merlino A, Vergara A, Verde C, Di Prisco G, Mazzarella L
Acta Crystallogr D Biol Crystallogr, 2005; N/D: N/D-N/D.
Impact Factor: 2.069
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* Structural And Dynamic Effects Of Alpha-Helix Deletion In Sso7d: Implications For Protein Thermal Stability (115 visite)
Merlino A, Graziano G, Mazzarella L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2004 Dec 1; 57(4): 692-701.
Impact Factor: 4.429
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* Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease - An enzyme tailored to evade ribonuclease protein inhibitor (122 visite)
Sica F, Di Fiore A, Merlino A, Mazzarella L
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2004 Sep 27; 279(35): 36753-36760.
Impact Factor: 6.355
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* Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer (146 visite)
Merlino A, Vitagliano L, Sica F, Zagari A, Mazzarella L
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004 Apr 15; 73(6): 689-695.
Impact Factor: 2.863
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* Dynamic properties of the N-terminal swapped dimer of ribonuclease (133 visite)
Merlino A, Vitagliano L, Ceruso MA, Mazzarella L
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2004 Apr; 86(4): 2383-2391.
Impact Factor: 4.585
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* Subtle functional collective motions in pancreatic-like ribonucleases: From ribonuclease A to angiogenin (125 visite)
Merlino A, Vitagliano L, Ceruso MA, Mazzarella L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2003 Oct 1; 53(1): 101-110.
Impact Factor: 4.313
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* Global and local motions in ribonuclease A: A molecular dynamics study (146 visite)
Merlino A, Vitagliano L, Ceruso M, Di Nola A, Mazzarella L
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002 Nov 15; 65(4): 274-283.
Impact Factor: 2.372
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* Reversible substrate-induced domain motions in ribonuclease (103 visite)
Vitagliano L, Merlino A, Zagari A, Mazzarella L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2002 Jan 1; 46(1): 97-104.
Impact Factor: 4.096
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Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2 ', 5 ')guanosine (152 visite)
Vitagliano L, Merlino A, Zagari A, Mazzarella L
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Jun; 9(6): 1217-1225.
Impact Factor: 3.869
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Reversible domain motions induced by substrate binding in ribonuclease (99 visite)
ZagariA, Berisio R, Merlino A, Sica F, Vitagliano L, Mazzarella L
Acta Crystallographica Section A, 2000; 56: 263-263.
Impact Factor: 2.33
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A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease (124 visite)
Vitagliano L, Adinolfi S, Sica F, Merlino A, Zagari A, Mazzarella L
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Oct 29; 293(3): 569-577.
Impact Factor: 5.501
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