* Cisplatin Binding Sites in Human H-Chain Ferritin (45 visite)
Ferraro G, Ciambellotti S, Messori L, Merlino A
Inorg Chem (ISSN: 1520-510xelectronic, 0020-1669linking), 2017 Aug 7; 56(15): 9064-9070.
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* A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin (45 visite)
Picone D, Donnarumma F, Ferraro G, Gotte G, Fagagnini A, Butera G, Donadelli M, Merlino A
J Chem Res (ISSN: 1873-3344electronic, 0162-0134linking, 0162-0134print), 2017 Aug; 173: 105-112.
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* Protein Metalation by Anticancer Metallodrugs: A Joint ESI MS and XRD Investigative Strategy (30 visite)
Merlino A, Marzo T, Messori L
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2017 May 23; 23(29): 6942-6947.
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* Mitochondria Targeting with Luminescent Rhenium(I) Complexes (44 visite)
Skiba J, Bernas T, Trzybinski D, Wozniak K, Ferraro G, Marasco D, Merlino A, Shafikov MZ, Czerwieniec R, Kowalski K
Molecules (ISSN: 1420-3049electronic, 1420-3049linking), 2017 May 15; 22(5): N/D-N/D.
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* X-ray Structure of the Carboplatin-Loaded Apo-Ferritin Nanocage (40 visite)
Pontillo N, Ferraro G, Helliwell JR, Amoresano A, Merlino A
Acs Med Chem Lett (ISSN: 1948-5875print, 1948-5875linking), 2017 Feb 28; 8(4): 433-437.
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* {Ru(CO)x}-Core complexes with benzimidazole ligands: synthesis, X-ray structure and evaluation of anticancer activity in vivo (62 visite)
Tamasi G, Merlino A, Scaletti F, Heffeter P, Legin AA, Jakupec MA, Berger W, Messori L, Keppler BK, Cini R
Dalton Trans (ISSN: 1477-9234electronic, 1477-9226linking), 2017 Feb 28; 46(9): 3025-3040.
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* Fine Sampling of the R--> T Quaternary-Structure Transition of a Tetrameric Hemoglobin (61 visite)
Vitagliano L, Mazzarella L, Merlino A, Vergara A
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2017 Jan 12; 23(3): 605-613.
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* Cisplatin binding to proteins: A structural perspective (114 visite)
Messori L, Merlino A
Coordination Chemistry Reviews (ISSN: 0010-8545), 2016; 315: 67-89.
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* Cisplatin encapsulation within a ferritin nanocage: A high-resolution crystallographic study (82 visite)
Pontillo N, Pane F, Messori L, Amoresano A, Merlino A
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2016; 52(22): 4136-4139.
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* Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme (67 visite)
Ferraro G, Pica A, Russo Krauss I, Pane F, Amoresano A, Merlino A
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2016; N/D: 1-10.
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* Protein conformational perturbations in hereditary amyloidosis: Differential impact of single point mutations in ApoAI amyloidogenic variants (97 visite)
Del Giudice R, Arciello A, Itri F, Merlino A, Monti M, Buonanno M, Penco A, Canetti D, Petruk G, Monti SM, Relini A, Pucci P, Piccoli R, Monti DM
Biochim Biophys Acta (ISSN: 0304-4165, 0006-3002, 0925-4439), 2016; 1860(2): 434-444.
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* The maturation mechanism of γ-glutamyl transpeptidases: Insights from the crystal structure of a precursor mimic of the enzyme from Bacillus licheniformis and from site-directed mutagenesis studies (87 visite)
Pica A, Chi M-C, Chen Y-Y, D'Ischia M, Lin L-L, Merlino A
Biochim Biophys Acta (ISSN: 1570-9639, 0925-4439, 0006-3002), 2016; 1864(2): 195-203.
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* Cisplatin binding to human serum albumin: A structural study (136 visite)
Ferraro G, Massai L, Messori L, Merlino A
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2015; 51(46): 9436-9439.
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* Fusion of raft-like lipid bilayers operated by a membranotropic domain of the HSV-type I glycoprotein gH occurs through a cholesterol-dependent mechanism (99 visite)
Vitiello G, Falanga A, Petruk AA, Merlino A, Fragneto G, Paduano L, Galdiero S, D'Errico G
Soft Matter (ISSN: 1744-683x), 2015; 11(15): 3003-3016.
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* Interaction of anticancer Ru(III) complexes with single stranded and duplex DNA model systems (115 visite)
Musumeci D, Rozza L, Merlino A, Paduano L, Marzo T, Massai L, Messori L, Montesarchio D
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2015; 44(31): 13914-13925.
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* Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts (87 visite)
Messori L, Marzo T, Merlino A
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; N/D: N/D-N/D.
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* α-thalassemia associated with Hb instability: A tale of two features. The case of Hb Rogliano or α1 Cod 108(G15)Thr→Asn and Hb Policoro or α2 Cod 124(H7)Ser→Pro (93 visite)
Bisconte MG, Caldora M, Musollino G, Cardiero G, Flagiello A, La Porta G, Lagona L, Prezioso R, Qualtieri G, Gaudiano C, Medulla E, Merlino A, Pucci P, Lacerra G
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2015; 10(3): N/D-N/D.
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* Missing gold atoms in lysozyme crystals used to grow gold nanoparticles (96 visite)
Merlino A, Caterino M, Russo Krauss I, Vergara A
Nat Nanotechnol Nature Nanotechnology (ISSN: 1748-3387), 2015; 10(4): 285-285.
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* Oxaliplatin vs. cisplatin: Competition experiments on their binding to lysozyme (74 visite)
Marasco D, Messori L, Marzo T, Merlino A
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2015; 44(22): 10392-10398.
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* Platinated oligomers of bovine pancreatic ribonuclease: Structure and stability (109 visite)
Picone D, Donnarumma F, Ferraro G, Russo Krauss I, Fagagnini A, Gotte G, Merlino A
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; 146: 37-43.
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* Platinum(II) Complexes with O, S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding (82 visite)
Mügge C, Marzo T, Massai L, Hildebrandt J, Ferraro G, Rivera-Fuentes P, Metzler-Nolte N, Merlino A, Messori L, Weigand W
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2015; 54(17): 8560-8570.
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* Structural evidences for a secondary gold binding site in the hydrophobic box of lysozyme (93 visite)
Ferraro G, Massai L, Messori L, Cinellu MA, Merlino A
Biometalsbiometals (ISSN: 0966-0844), 2015; 28(4): 745-754.
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* The X-ray structure of the primary adducts formed in the reaction between cisplatin and cytochrome (85 visite)
Ferraro G, Messori L, Merlino A
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2015; 51(13): 2559-2561.
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* Interaction between Proteins and Ir Based CO Releasing Molecules: Mechanism of Adduct Formation and CO Release (119 visite)
Petruk AA, Vergara A, Marasco D, Bikiel D, Doctorovich F, Estrin DA, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2014 Oct 6; 53(19): 10456-10462.
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* Protein Recognition of Gold-Based Drugs: 3D Structure of the Complex Formed When Lysozyme Reacts with Aubipy(c) (106 visite)
Messori L, Cinellu MA, Merlino A
Acs Med Chem Lett (ISSN: 1948-5875, 1948-5875print, 1948-5875linking), 2014 Jul 31; 5(10): 1110-1113.
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* Comments on Structural studies of haemoglobin from pisces species shortfin mako shark (Isurus oxyrinchus) at 1. 9 angstrom resolution by P. Ramesh et al. (2013). J. Synchrotron Rad. 20, 843-847 (92 visite)
Merlino A, Vergara A, Vitagliano L
Journal Of Synchrotron Radiation (ISSN: 0909-0495), 2014 Jul; 21: N/D-N/D.
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* Molecular bases of protein halotolerance (123 visite)
Graziano G, Merlino A
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2014 Apr; 1844(4): 850-858.
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* Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability (123 visite)
Merlino A, Russo Krauss I, Castellano I, Ruocco MR, Capasso A, De Vendittis E, Rossi B, Sica F
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2014 Mar; 1844(3): 632-640.
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* A regular thymine tetrad and a peculiar supramolecular assembly in the first crystal structure of an all-LNA G-quadruplex (116 visite)
Russo Krauss I, Parkinson GN, Merlino A, Mattia CA, Randazzo A, Novellino E, Mazzarella L, Sica F
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2014 Feb; 70(2): 362-370.
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* Reaction of Hg2+ Insertion into Cysteine Pairs Within Bovine Insulin Crystals Followed via Raman Spectroscopy (102 visite)
Caterino M, Merlino A, Balsamo A, Russo Krauss I, Parisi S, Vergara A
Journal Of Solution Chemistry (ISSN: 0095-9782), 2014 Feb; 43(1): 135-143.
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* Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(III) compound (90 visite)
Messori L, Scaletti F, Massai L, Cinellu MA, Russo Krauss I, Di Martino G, Vergara A, Paduano L, Merlino A
Metallomics (ISSN: 1756-5901, 1756-591x, 1756-591xelectronic), 2014; 6(2): 233-236.
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* Interactions of gold-based drugs with proteins: the structure and stability of the adduct formed in the reaction between lysozyme and the cytotoxic gold(III) compound Auoxo3 (120 visite)
Russo Krauss I, Messori L, Cinellu MA, Marasco D, Sirignano R, Merlino A
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2014; 43(46): 17483-17488.
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* γ-Glutamyl transpeptidase architecture: Effect of extra sequence deletion on autoprocessing, structure and stability of the protein from Bacillus licheniformis (92 visite)
Chi M-C, Lo Y-H, Chen Y-Y, Lin L-L, Merlino A
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2014; 1844(12): 2290-2297.
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* Low resolution X-ray structure of γ-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion (104 visite)
Lin L-L, Chen Y-Y, Chi M-C, Merlino A
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2014; 1844(9): 1523-1529.
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* Structural modifications induced by the switch from an endogenous bis-histidyl to an exogenous cyanomet hexa-coordination in a tetrameric haemoglobin (89 visite)
Mazzarella L, Merlino A, Vitagliano L, Verde C, Di Prisco G, Peisach J, Vergara A
Rsc Advances (ISSN: 2046-2069), 2014; 4(49): 25852-25856.
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* Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer (152 visite)
Pica A, Russo Krauss I, Merlino A, Nagatoishi S, Sugimoto N, Sica F
Febs Journal (ISSN: 1742-464x), 2013 Dec; 280(24): 6581-6588.
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* Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer (99 visite)
Russo Krauss I, Pica A, Merlino A, Mazzarella L, Sica F
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Dec; 69(12): 2403-2411.
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* The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer (114 visite)
Sica F, Pica A, Merlino A, Russo Krauss I, Ercole C, Picone D
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013 Nov 29; 587(23): 3755-3762.
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* The Structure Of The Cd3 Zeta Zeta Transmembrane Dimer In Popc And Raft-Like Lipid Bilayer: A Molecular Dynamics Study (112 visite)
Petruk AA, Varriale S, Coscia MR, Mazzarella L, Merlino A, Oreste U
Biochim Biophys Acta (ISSN: 0005-2736, 0006-3002e), 2013 Nov; 1828(11): 2637-2645.
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* Investigating the Ruthenium Metalation of Proteins: X-ray Structure and Raman Microspectroscopy of the Complex between RNase A and AziRu (87 visite)
Vergara A, Russo Krauss I, Montesarchio D, Paduano L, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Oct 7; 52(19): 10714-10716.
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* Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase (127 visite)
Pica A, Merlino A, Buell AK, Knowles TJ, Pizzo E, D'Alessio G, Sica F, Mazzarella L
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Oct; 69: 2116-2123.
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* Molecular basis of the NO trans influence in quaternary T-state human hemoglobin: A computational study (87 visite)
Alcides Petruk A, Vergara A, Estrin D, Merlino A
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013 Sep 2; 587(15): 2393-2398.
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* Role of tertiary structures on the Root effect in fish hemoglobins (119 visite)
Ronda L, Merlino A, Bettati S, Verde C, Balsamo A, Mazzarella L, Mozzarelli A, Vergara A
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Sep; 1834(9): 1885-1893.
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* A Novel Interdomain Interface In Crystallins: Structural Characterization Of The Beta Gamma-Crystallin From Geodia Cydonium At 0. 99 Angstrom Resolution (152 visite)
Vergara A, Grassi M, Sica F, Pizzo E, D’Alessio G, Mazzarella L, Merlino A
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jun; 69(6): 960-967.
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* An overview of biological macromolecule crystallization (161 visite)
Russo Krauss I, Merlino A, Vergara A, Sica F
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2013 May 31; 14(6): 11643-11691.
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* Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu (106 visite)
Vergara A, D’Errico G, Montesarchio D, Mangiapia G, Paduano L, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Apr 15; 52(8): 4157-4159.
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* Effect Of Nacl On The Conformational Stability Of The Thermophilic Gamma-Glutamyltranspeptidase From Geobacillus Thermodenitrificans: Implication For Globular Protein Halotolerance (96 visite)
Pica A, Russo Krauss I, Castellano I, La Cara F, Graziano G, Sica F, Merlino A
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Jan; 1834(1): 149-157.
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* Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study (91 visite)
Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jan; 69: 137-140.
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* Cholesterol modulates the fusogenic activity of a membranotropic domain of the FIV glycoprotein gp36 (78 visite)
Vitiello G, Fragneto G, Petruk AA, Falanga A, Galdiero S, D'Ursi A, Merlino A, D'Errico G
(ISSN: 1744-683x), 2013; 9(28): 6442-6456.
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* Duplex-Quadruplex Motifs In A Novel Structural Organization Cooperatively Contribute To Thrombin Binding Of Hd22-27mer (94 visite)
Russo Krauss I, Pica A, Merlino A, Mazzarella L, Sica F
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013; D69: 2403-2411.
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* Heterogeneous nucleation helps the search for initial crystallization conditions of γ-glutamyl transpeptidase from Bacillus licheniformis (86 visite)
Lin LL, Merlino A
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013; 69(6): 669-672.
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* Investigating The Ruthenium Metallation Of Proteins: X-Ray Structure And Raman Microspectroscopy Of The Complex Between Rnase A And Aziru (90 visite)
Vergara A, Montesarchio D, Russo Krauss I, Paduano L, Merlino A
Inorg Chem (ISSN: 0020-1669, 1520-510xe, 1520-510xelectronic), 2013; 52(19): 10714-10716.
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* Selective X-Ray Induced No-Photodissociation In Hemoglobin Crystals: Evidence From A Raman Assisted-Crystallographic Study (82 visite)
Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
Acta Cryst D 69, 2013; 1: 137-140.
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* The mode of action of anticancer gold-based drugs: a structural perspective (98 visite)
Messori L, Scaletti F, Massai L, Cinellu MA, Gabbiani C, Vergara A, Merlino A
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2013; 49(86): 10100-10102.
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* ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus (85 visite)
Coppola D, Abbruzzetti S, Nicoletti F, Merlino A, Gambacurta A, Giordano D, Howes BD, De Sanctis G, Vitagliano L, Bruno S, di Prisco G, Mazzarella L, Smulevich G, Coletta M, Viappiani C, Vergara A, Verde C
Molecular Biosystems (ISSN: 1742-206x), 2012 Oct 30; 8(12): 3295-3304.
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* High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity (112 visite)
Russo Krauss I, Merlino A, Randazzo A, Novellino E, Mazzarella L, Sica F
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2012 Sep; 40(16): 8119-8128.
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* Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease (88 visite)
Merlino A, Picone D, Ercole C, Balsamo A, Sica F
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 May; 94(5): 1108-1118.
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* Exploring The Unfolding Mechanism Of Gamma-Glutamyltranspeptidases: The Case Of The Thermophilic Enzyme From Geobacillus Thermodenitrificans (109 visite)
Pica A, Russo Krauss I, Castellano I, Rossi M, La Cara F, Graziano G, Sica F, Merlino A
Biochim Biophys Acta (ISSN: 1570-9639, 0006-3002, 0925-4439), 2012 Apr; 1824(4): 571-577.
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* Role of the tertiary and quaternary structure in the formation of bis-histidyl adducts in cold-adapted hemoglobins (104 visite)
Balsamo A, Sannino F, Merlino A, Parrilli E, Tutino ML, Mazzarella L, Vergara A
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 Apr; 94(4): 953-960.
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* Identification of an active dimeric intermediate populated during the unfolding process of the cambialistic superoxide dismutase from Streptococcus mutans (99 visite)
Merlino A, Russo Krauss I, Rossi B, De Vendittis A, Marco S, De Vendittis E, Vergara A, Sica F
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 Mar; 94(3): 768-775.
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* Increasing the X-ray diffraction power of protein crystals by dehydration: the case of bovine serum albumin and a survey of literature data (119 visite)
Russo Krauss I, Sica F, Mattia CA, Merlino A
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2012 Mar; 13(3): 3782-3800.
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* Destabilization of Lipid Membranes by a Peptide Derived from Glycoprotein gp36 of Feline Immunodeficiency Virus: A Combined Molecular Dynamics/Experimental Study (87 visite)
Merlino A, Vitiello G, Grimaldi M, Sica F, Busi E, Basosi R, D’Ursi A, Fragneto G, Paduano L, D’Errico G
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2012 Jan 12; 116(1): 401-412.
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* γ-glutamyltranspeptidases: Sequence, structure, biochemical properties, and biotechnological applications (97 visite)
Castellano I, Merlino A
Cell Mol Life Sci (ISSN: 1420-682x), 2012; 69(20): 3381-3394.
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* Improving Protein Crystal Quality by the Without-Oil Microbatch Method: Crystallization and Preliminary X-ray Diffraction Analysis of Glutathione Synthetase from Pseudoalteromonas haloplanktis (103 visite)
Merlino A, Russo Krauss I, Albino A, Pica A, Vergara A, Masullo M, De Vendittis E, Sica F
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2011 Sep; 12(9): 6312-6319.
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* Occurrence and formation of endogenous histidine hexa-coordination in cold-adapted hemoglobins (93 visite)
Merlino A, Howes BD, Prisco G, Verde C, Smulevich G, Mazzarella L, Vergara A
Iubmb Life (ISSN: 1521-6543, 1521-6551), 2011 May; 63(5): 295-303.
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* A novel ErbB2 epitope targeted by human antitumor immunoagents (111 visite)
Troise F, Monti M, Merlino A, Cozzolino F, Fedele C, Russo Krauss I, Sica F, Pucci P, D'Alessio G, De Lorenzo C
Febs Journal (ISSN: 1742-464x), 2011 Apr; 278(7): 1156-1166.
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* Protonation of Histidine 55 Affects the Oxygen Access to Heme in the Alpha Chain of the Hemoglobin from the Antarctic Fish Trematomus bernacchii (92 visite)
Boechi L, Marti MA, Vergara A, Sica F, Mazzarella L, Estrin DA, Merlino A
Iubmb Life (ISSN: 1521-6543, 1521-6551), 2011 Mar; 63(3): 175-182.
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* A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish (116 visite)
Pizzo E, Merlino A, Turano M, Russo Krauss I, Coscia F, Zanfardino A, Varcamonti M, Furia A, Giancola C, Mazzarella L, Sica F, D'Alessio G
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2011 Jan 15; 433(2): 345-355.
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* Gene cloning and protein expression of γ-glutamyltranspeptidases from Thermus thermophilus and Deinococcus radiodurans: Comparison of molecular and structural properties with mesophilic counterparts (84 visite)
Castellano I, Di Salle A, Merlino A, Rossi M, La Cara F
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic), 2011; 15(2): 259-270.
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* Thrombin-aptamer recognition: a revealed ambiguity (91 visite)
Russo Krauss I, Merlino A, Giancola C, Randazzo A, Mazzarella L, Sica F
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2011; 39(17): 7858-7867.
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* An evolutionary conserved motif is responsible for Immunoglobulin heavy chain packing in the B cell membrane (97 visite)
Varriale S, Merlino A, Coscia MR, Mazzarella L, Oreste U
Molecular Phylogenetics And Evolution (ISSN: 1055-7903), 2010 Dec; 57(3): 1238-1244.
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* Structure and flexibility in cold-adapted iron superoxide dismutases: The case of the enzyme isolated from Pseudoalteromonas haloplanktis (117 visite)
Merlino A, Russo Krauss I, Castellano I, De Vendittis E, Rossi B, Conte M, Vergara A, Sica F
Journal Of Structural Biology (ISSN: 1047-8477), 2010 Dec; 172(3): 343-352.
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* Crystallization, preliminary X-ray diffraction studies and Raman microscopy of the major haemoglobin from the sub-Antarctic fish Eleginops maclovinus in the carbomonoxy form (74 visite)
Merlino A, Vitagliano L, Balsamo A, Nicoletti FP, Howes BD, Giordano D, Coppola D, Di Prisco G, Verde C, Smulevich G, Mazzarella L, Vergara A
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2010 Nov; 66: 1536-1540.
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* An Order-Disorder Transition Plays a Role in Switching Off the Root Effect in Fish Hemoglobins (91 visite)
Vergara A, Vitagliano L, Merlino A, Sica F, Marino K, Verde C, di Prisco G, Mazzarella L
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2010 Oct 15; 285(42): 32568-32575.
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* Crystallization and preliminary X-ray analysis of the complex of human alpha-thrombin with a modified thrombin-binding aptamer (95 visite)
Russo Krauss I, Merlino A, Randazzo A, Mazzarella L, Sica F
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309, 1532-2335electronic), 2010 Aug 1; 66(Pt8): 961-963.
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* Free-Energy Profile for CO Binding to Separated Chains of Human and Trematomus newnesi Hemoglobin: Insights from Molecular Dynamics Simulations and Perturbed Matrix Method (81 visite)
Merlino A, Vergara A, Sica F, Aschi M, Amadei A, Di Nola A, Mazzarella L
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 May 27; 114(20): 7002-7008.
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* Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity (189 visite)
Castellano I, Merlino A, Rossi M, La Cara F
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2010 May; 92(5): 464-474.
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* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (88 visite)
Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
Biochim Biophys Acta (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
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* Combined Crystallographic and Spectroscopic Analysis of Trematomus bernacchii Hemoglobin Highlights Analogies and Differences in the Peculiar Oxidation Pathway of Antarctic Fish Hemoglobins (87 visite)
Merlino A, Vitagliano L, Howes BD, Verde C, Di Prisco G, Smulevich G, Sica F, Vergara A
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1117-1125.
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* Toward an Antitumor Form of Bovine Pancreatic Ribonuclease: The Crystal Structure of Three Noncovalent Dimeric Mutants (92 visite)
Merlino A, Russo Krauss I, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1029-1037.
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* Correlation between Hemichrome Stability and the Root Effect in Tetrameric Hemoglobins (99 visite)
Vergara A, Franzese M, Merlino A, Bonomi G, Verde C, Giordano D, Di Prisco G, Lee HC, Peisach J, Mazzarella L
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2009 Sep 5; 97(3): 866-874.
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* The bis-histidyl complex in hemoproteins: A detailed conformational analysis of database protein structures and the case of Antarctic fish hemoglobins (101 visite)
Merlino A, Vergara A, Sica F, Mazzarella L
Marine Genomics (ISSN: 1874-7787), 2009 Mar; 2(1): 51-56.
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* Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant (82 visite)
Merlino A, Avella G, Di Gaetano S, Arciello A, Piccoli R, Mazzarella L, Sica F
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic, 0961-8368linking), 2009 Jan; 18(1): 50-57.
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* Structure and dimerization of the teleost transmembrane immunoglobulin region (115 visite)
Merlino A, Varriale S, Coscia MR, Mazzarella L, Oreste U
Journal Of Molecular Graphics & Modelling (ISSN: 1093-3263), 2008 Oct; 27(3): 401-407.
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* Spectroscopic and crystallographic characterization of a tetrameric hemoglobin oxidation reveals structural features of the functional intermediate relaxed/tense state (102 visite)
Vitagliano L, Vergara A, Bonomi G, Merlino A, Verde C, Di Prisco G, Howes BD, Smulevich G, Mazzarella L
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2008 Sep 13; 130(32): 10527-10535.
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* Correlation between Raman and X-ray crystallography data of (Pro-Pro-Gly)(10) (85 visite)
Merlino A, Sica F, Mazzarella L, Zagari A, Vergara A
Biophysical Chemistry (ISSN: 0301-4622), 2008 Sep; 137(1): 24-27.
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* The buried diversity of bovine seminal ribonuclease: Shape and cytotoxicity of the swapped non-covalent form of the enzyme (80 visite)
Merlino A, Ercole C, Picone D, Pizzo E, Mazzarella L, Sica F
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2008 Feb 15; 376(2): 427-437.
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* A novel method for detection of selenomethionine incorporation in protein crystals via Raman microscopy (97 visite)
Vergara A, Merlino A, Pizzo E, D'Alessio G, Mazzarella L
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2008 Feb; 64: 167-171.
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* A Novel Method For Detection Of Se-Met Inclusion Into Protein Crystals Via Raman Microscopy (87 visite)
Vergara A, Merlino A, Pizzo E, D'Alessio G, Mazzarella L
Acta Crystallogr D Biol Crystallogr, 2008; N/D: 167-171.
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* Crystallization and preliminary x-ray diffraction studies of a psychrophilic iron superoxide dismutase from Pseudoalteromonas haloplanktis (68 visite)
Merlino A, Russo Krauss I, Castellano I, De Vendittis E, Vergara A, Sica F
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2008; 15(4): 415-418.
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* Reduction of ferric hemoglobin from Trematomus bernacchii in a partial bis-histidyl state produces a deoxy coordination even when encapsulated into the crystal phase (78 visite)
Merlino A, Verde C, Di Prisco G, Mazzarella L, Vergara A
Spectroscopy An International Journal (ISSN: 0712-4813), 2008; 22(2-3): 143-152.
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* Spectroscopic And Crystallographic Characterization Of A Tetrameric Hemoglobin Oxidation Pathway Reveals Structural Features Of A Functional Intermediate R/T State (77 visite)
Vitagliano L, Vergara A, Bonomi G, Merlino A, Verde C, Di Prisco G, Howes BD, Smulevich G, Mazzarella L
Biophys J, 2008; 94: 4031-4040.
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* Structural characterization of ferric hemoglobins from three Antarctic fish species of the suborder notothenioidei (86 visite)
Vergara A, Franzese M, Merlino A, Vitagliano L, Verde C, Di Prisco G, Lee HC, Peisach J, Mazzarella L
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2007 Oct; 93(8): 2822-2829.
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* Approximate values for force constant and wave number associated with a low-frequency concerted motion in proteins can be evaluated by a comparison of X-ray structures (78 visite)
Merlino A, Sica F, Mazzarella L
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2007 May 17; 111(19): 5483-5486.
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* High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect (94 visite)
Mazzarella L, Vergara A, Vitagliano L, Merlino A, Bonomi G, Scala S, Verde C, Di Prisco G
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Nov 1; 65(2): 490-498.
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* Polyglutamine Repeats And Beta-Helix Structure: Molecular Dynamics Study (112 visite)
Merlino A, Esposito L, Vitagliano L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Jun 1; 63(4): 918-927.
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* Minimal structural requirements for root effect: Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus newnesi (121 visite)
Mazzarella L, Bonomi G, Lubrano MC, Merlino A, Riccio A, Vergara A, Vitagliano L, Verde C, Di Prisco G
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Feb 1; 62(2): 316-321.
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* The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase mutants (100 visite)
Merlino A, Mazzarella L, Carannante A, Di Fiore A, Di Donato A, Notomista E, Sica F
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2005 May 6; 280(18): 17953-17960.
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* Open interface and large quaternary structure movements in 3D domain swapped proteins: Insights from molecular dynamics simulations of the C-terminal swapped dimer of ribonuclease (117 visite)
Merlino A, Ceruso MA, Vitagliano L, Mazzarella L
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2005 Mar; 88(3): 2003-2012.
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* Structural Characterization Of The Oxidation Pathway Of Antarctic Fish Hemoglobins (83 visite)
Vitagliano L, Bonomi G, Franzese M, Merlino A, Vergara A, Verde C, Di Prisco G, Mazzarella L
Acta Crystallogr D Biol Crystallogr, 2005; N/D: N/D-N/D.
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* Structural And Dynamic Effects Of Alpha-Helix Deletion In Sso7d: Implications For Protein Thermal Stability (92 visite)
Merlino A, Graziano G, Mazzarella L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2004 Dec 1; 57(4): 692-701.
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* Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease - An enzyme tailored to evade ribonuclease protein inhibitor (104 visite)
Sica F, Di Fiore A, Merlino A, Mazzarella L
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2004 Sep 27; 279(35): 36753-36760.
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* Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer (93 visite)
Merlino A, Vitagliano L, Sica F, Zagari A, Mazzarella L
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004 Apr 15; 73(6): 689-695.
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* Dynamic properties of the N-terminal swapped dimer of ribonuclease (95 visite)
Merlino A, Vitagliano L, Ceruso MA, Mazzarella L
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2004 Apr; 86(4): 2383-2391.
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* Subtle functional collective motions in pancreatic-like ribonucleases: From ribonuclease A to angiogenin (94 visite)
Merlino A, Vitagliano L, Ceruso MA, Mazzarella L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2003 Oct 1; 53(1): 101-110.
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* Global and local motions in ribonuclease A: A molecular dynamics study (90 visite)
Merlino A, Vitagliano L, Ceruso M, Di Nola A, Mazzarella L
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002 Nov 15; 65(4): 274-283.
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* Reversible substrate-induced domain motions in ribonuclease (73 visite)
Vitagliano L, Merlino A, Zagari A, Mazzarella L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2002 Jan 1; 46(1): 97-104.
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Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2 ', 5 ')guanosine (106 visite)
Vitagliano L, Merlino A, Zagari A, Mazzarella L
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Jun; 9(6): 1217-1225.
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Reversible domain motions induced by substrate binding in ribonuclease (65 visite)
ZagariA, Berisio R, Merlino A, Sica F, Vitagliano L, Mazzarella L
Acta Crystallographica Section A, 2000; 56: 263-263.
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A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease (93 visite)
Vitagliano L, Adinolfi S, Sica F, Merlino A, Zagari A, Mazzarella L
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Oct 29; 293(3): 569-577.
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