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Name Nome | Fiorella Altruda |
Area | Associated Scientist Associati |
Position Qualifica | Associated Scientist Associato |
Work site Sede | Turin Torino |
Address Indirizzo | Via Nizza, Turin Torino - Italy |
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Office phone Telefono ufficio | +39 0116706414 |
No research areas Nessuna area di ricerca |
No activities Nessuna attivitá |
Name: Fiorella Altruda -Born in Turin, the 12th of August 1952 - Ph D in Biology , University of Turin, July 1975 -Full Professor of Molecular Genetics
ACADEMIC APPOINTMENTS From 1987 to 1994: Associate Professor in Genetics 1994-at present: Full Professor in Molecular Genetics, University of Torino, School of Medicine From 2005: President of the School of Biotechnology, University of Turin From 2010: Coordinator of the European Master Program in BioHealth Computing for the University of Torino From 2002 Scientific member of the Consorzio Interuniversitario Biotecnologie (CIB) and member of the Executive Board from 2014 Director of the Center for in vivo functional Genomics, University of Turin, supported by Telethon From 2009: University coordinator of the Polo di Innovazione- Biotecnologie (BioPmed), Regione Piemonte From 2012: Member of the Director Board of the University Federico II, Naples From 2013: Director of the Molecular Biotechnology Center, University of Torino From 2013: in charge of the organization of the Cell Factory, University of Torino From 2012: member of the Scientific Board of CentroScienza Foundation and from 2014 member of the Executive Board From 2015: President of the Bioindustry Park S.p.A. Colleretto Giacosa (Torino)
PAST RELEVANT RESEARCH EXPERIENCE IN FOREIGN INSTITUTION
November 1976-December 1977 Postdoctoral fellow- Dept. of Molecular Biophysics and Biochemistry, Yale University, USA January-April 1981 Visiting fellow- Dept. of Animal Embryology, University of Geneva, Switzerland January 1982-December 1982 Postdoctoral fellow, European Molecular Biology Laboratory, Heidelberg, Germany October-December 1984 Visiting fellow- European Molecular Biology Laboratory, Heidelberg, Germany July-September 1989 Visiting scientist, Scripps Clinic and Research Laboratory, La Jolla, USA
CURRENT RESEARCH INTEREST
One of the current research interests is to explore the potentiality of spermatogonial stem cells as a novel tool for cell therapy, with particular emphasis on liver metabolic diseases. Spermatogonial stem cells have been isolated from mice and are currently in culture in the laboratory. These stem cells have been found to convert spontaneously to pluripotent stem cells, termed germ cell-derived pluripotent stem cells or GPSCs. However, very little is known about the factors responsible for the conversion of spermatogonial stem cells to pluripotent stem cells. The Unit has developed a system for differentiating GPSCs into hepatocyte-like cells and renal cells and research on this aspects is presently under way. The main aims are to:-Develop culture conditions and identify factors responsible to differentiate GPSCs into hepatocytes as well as renal cells.-Employ a bioinformatics approach to identify genes that are enhancers of reprogramming. Patents: 1) 19 December 2002 (WO2004056176) “MELUSIN, A MUSCLE SPECIFIC PROTEIN, AS A DRUG TARGET FOR PREVENTION AND TREATMENT OF HEART FAILURE AND APPLICATIONS THEREOF” Il brevetto è di proprietà dell’Università di Torino e gli inventori sono: Mara Brancaccio, Lorenzo Silengo, Fiorella Altruda, Giuseppe Lembo, Luigi Fratta, e Guido Tarone. 2) 17 Gennaio 2012 M.G. Faga, A. Bellosi, F. Altruda, S. Carossa, S. Coluccia, G. Martra, F. Mussano, E. Tolosano (2012). Impianto dentale od osseo, in particolare in nanocomposito allumina-zirconia. TO2012A000029, 50% Università degli Studi di Torino, 50%
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