* Exploring the ability of cyclic peptides to target SAM domains: a computational and experimental study (42 visite)
Mercurio FA, Di Natale C, Pirone L, Vincenzi M, Marasco D, De Luca S, Pedone EM, Leone M
Chembiochem (ISSN: 1439-4227linking, 1439-7633), 2019 Sep 20; N/D: N/D-N/D.
Impact Factor: 2.641
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* KCTD1: A novel modulator of adipogenesis through the interaction with the transcription factor AP2alpha (39 visite)
Pirone L, Smaldone G, Spinelli R, Barberisi M, Beguinot F, Vitagliano L, Miele C, Di Gaetano S, Raciti GA, Pedone E
Biochim Biophys Acta Mol Cell Biol Lipids (ISSN: 1388-1981linking), 2019 Aug 26; 1864(12): 158514-158514.
Impact Factor: 4.402
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* A physicochemical investigation on the metal binding properties of TtSmtB, a thermophilic member of the ArsR/SmtB transcription factor family (36 visite)
Gallo G, Antonucci I, Pirone L, Amoresano A, Contursi P, Limauro D, Pedone E, Bartolucci S, Fiorentino G
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2019 Jul 26; 138: 1056-1063.
Impact Factor: 4.784
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* Investigating the properties of TBA variants with twin thrombin binding domains (37 visite)
Amato T, Virgilio A, Pirone L, Vellecco V, Bucci M, Pedone E, Esposito V, Galeone A
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic), 2019 Jun 24; 9(1): 9184-9184.
Impact Factor: 5.078
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* Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation (86 visite)
Pirone L, Caldinelli L, Di Lascio S, Di Girolamo R, Di Gaetano S, Fornasari D, Pollegioni L, Benfante R, Pedone E
Febs J (ISSN: 1742-464xlinking), 2019 Apr 7; 286(13): 2505-2521.
Impact Factor: 3.129
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* Design and analysis of EphA2-SAM peptide ligands: A multi-disciplinary screening approach (73 visite)
Mercurio FA, Di Natale C, Pirone L, Marasco D, Calce E, Vincenzi M, Pedone EM, De Luca S, Leone M
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2019 Mar; 84: 434-443.
Impact Factor: 3.929
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* Focusing on the functional characterization of the anserinase from Oreochromis niloticus (64 visite)
Pirone L, Di Gaetano S, Rizzarelli E, Bellia F, Pedone E
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2019 Feb 22; 130: 158-165.
Impact Factor: 4.784
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* Ubiquitin binds the amyloid beta peptide and interferes with its clearance pathways (53 visite)
Bellia F, Lanza V, Garcia-vinuales S, Ahmed IMM, Pietropaolo A, Iacobucci C, Malgieri G, D'Abrosca G, Fattorusso R, Nicoletti VG, Sbardella D, Tundo GR, Coletta M, Pirone L, Pedone E, Calcagno D, Grasso G, Milardi D
Chem Sci (ISSN: 2041-6520linking, 2041-6520print), 2019 Jan 10; 10 (9 ): 2732-2742.
Impact Factor: 8.668
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* Identifying the region responsible for Brucella abortus MucR higher-order oligomer formation and examining its role in gene regulation (57 visite)
Pirone L, Pitzer JE, D'Abrosca G, Fattorusso R, Malgieri G, Pedone EM, Pedone PV, Roop RM, Baglivo I
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2018 Nov 22; 8(1): 17238-17238.
Impact Factor: 5.078
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* Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2 (115 visite)
Mercurio FA, Pirone L, Di Natale C, Marasco D, Pedone EM, Leone M
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2018 Oct; 80: 602-610.
Impact Factor: 3.9
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* The essential player in adipogenesis GRP78 is a novel KCTD15 interactor (75 visite)
Smaldone G, Pirone L, Capolupo A, Vitagliano L, Monti MC, Di Gaetano S, Pedone E
Int J Biol Macromol (ISSN: 1879-0003electronic, 0141-8130linking), 2018 Aug; 115: 469-475.
Impact Factor: 4.784
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* Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins (129 visite) (PDF 33 visite)
Malgieri G, D'Abrosca G, Pirone L, Toto A, Palmieri M, Russo L, Sciacca MFM, Tate R, Sivo V, Baglivo I, Majewska R, Coletta M, Pedone PV, Isernia C, De Stefano M, Gianni S, Pedone EM, Milardi D, Fattorusso R
Chem Sci (ISSN: 2041-6520linking, 2041-6520print, 2041-6539), 2018 Apr 7; 9(13): 3290-3298.
Impact Factor: 9.063
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* MucR binds multiple target sites in the promoter of its own gene and is a heat-stable protein: Is MucR a H-NS-like protein? (43 visite)
Baglivo I, Pirone L, Malgieri G, Fattorusso R, Roop Ii RM, Pedone EM, Pedone PV
Febs Open Biofebs Open Bio (ISSN: 2211-5463print, 2211-5463linking), 2018 Mar 31; 8(4): 711-718.
Impact Factor: 2.999
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* A selective αvβ5 integrin antagonist hidden into the anophelin family protein cE5 from the malaria vector Anopheles gambiae (70 visite)
Di Gaetano S, Del Gatto A, Pirone L, Comegna D, Zaccaro L, Saviano M, Arcà B, Capasso D, Pedone E
Peptide Science, 2018; N/D: N/D-N/D.
Impact Factor: 2.081
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* The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors (118 visite)
Mercurio FA, Di Natale C, Pirone L, Iannitti R, Marasco D, Pedone EM, Palumbo R, Leone M
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Dec 12; 7(1): 17474-17474.
Impact Factor: 4.122
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* Ml proteins from Mesorhizobium loti and MucR from Brucella abortus: an AT-rich core DNA-target site and oligomerization ability (82 visite)
Baglivo I, Pirone L, Pedone E, Pitzer JE, Muscariello L, Marino MM, Malgieri G, Freschi A, Chambery A, Roop Ii RM, Pedone PV
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Nov 17; 7(1): 15805-15805.
Impact Factor: 4.122
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* Functional analyses yield detailedinsight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae (118 visite) (PDF 114 visite)
Pirone L, Ripoll-rozada J, Leone M, Ronca R, Lombardo F, Fiorentino G, Andersen JF, Pereira PJB, Arcà B, Pedone E
Jbc Papers (ISSN: 0021-9258linking, 1083-351x), 2017 Jul 28; 292(30): 12632-12642.
Impact Factor: 4.125
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* Insights into the anticancer properties of the first antimicrobial peptide from Archaea (155 visite)
Gaglione R, Pirone L, Farina B, Fusco S, Smaldone G, Aulitto M, Dell'Olmo E, Roscetto E, Del Gatto A, Fattorusso R, Notomista E, Zaccaro L, Arciello A, Pedone E, Contursi P
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 0304-4165linking), 2017 Jun 15; 1861(9): 2155-2164.
Impact Factor: 4.28
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* Structural investigation of a C-terminal EphA2 receptor mutant: Does mutation affect the structure and interaction properties of the Sam domain? (110 visite)
Mercurio FA, Costantini S, Di Natale C, Pirone L, Guariniello S, Scognamiglio PL, Marasco D, Pedone EM, Leone M
Bba-Bioenergetics (ISSN: 0005-2728, 0006-3002print, 1570-9639linking), 2017 Jun 06; 1865(9): 1095-1104.
Impact Factor: 4.28
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* A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 beta-like: from in silico identification to experimental evidence (184 visite)
Bosso A, Pirone L, Gaglione R, Pane K, Del Gatto A, Zaccaro L, Di Gaetano S, Diana D, Fattorusso R, Pedone E, Cafaro V, Haagsman HP, Van Dijk A, Scheenstra MR, Zanfardino A, Crescenzi O, Arciello A, Varcamonti M, Veldhuizen EJA, Di Donato A, Notomista E, Pizzo E
Bba-Bioenergetics (ISSN: 0005-2728, 0006-3002print), 2017 Apr 25; N/D: N/D-N/D.
Impact Factor: 4.28
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* Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility (102 visite)
Sacchi S, Cappelletti P, Pirone L, Smaldone G, Pedone E, Pollegioni L
Febs Lett (ISSN: 1873-3468, 0014-5793, 0014-5793print), 2017 Feb; 591(4): 646-655.
Impact Factor: 2.999
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* Targeting EphA2-Sam and Its Interactome: Design and Evaluation of Helical Peptides Enriched in Charged Residues (206 visite)
Mercurio FA, Marasco D, Di Natale C, Pirone L, Costantini S, Pedone EM, Leone M
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-4227linking), 2016 Nov 17; 17(22): 2179-2188.
Impact Factor: 2.847
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* Proteins involved in sleep homeostasis: Biophysical characterization of INC and its partners (159 visite) (PDF 123 visite)
Pirone L, Smaldone G, Esposito C, Balasco N, Petoukhov MV, Spilotros A, Svergun DI, Di Gaetano S, Vitagliano L, Pedone E
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2016 Sep 24; N/D: N/D-N/D.
Impact Factor: 3.112
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* Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction (119 visite) (PDF 138 visite)
Birolo L, Sacchi S, Smaldone G, Molla G, Leo G, Caldinelli L, Pirone L, Eliometri P, Di Gaetano S, Orefice I, Pedone E, Pucci P, Pollegioni L
Febs J (ISSN: 1742-464x), 2016 Sep; 283(18): 3353-3370.
Impact Factor: 3.902
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* The BTB domains of the potassium channel tetramerization domain proteins prevalently assume pentameric states (119 visite)
Smaldone G, Pirone L, Pedone E, Marlovits T, Vitagliano L, Ciccarelli L
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468), 2016 Jun; 590(11): 1663-1671.
Impact Factor: 3.623
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* Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions (164 visite)
Esposito V, Pirone L, Mayol L, Pedone E, Virgilio A, Galeone A
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2016; 127: 19-22.
Impact Factor: 3.112
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* Cullin 3 recognition is not a universal property among KCTD proteins (220 visite)
Smaldone G, Pirone L, Balasco N, Di Gaetano S, Pedone E, Vitagliano L
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2015 May 14; 10(5): e0126808-e0126808.
Impact Factor: 3.057
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* Cullin3 - BTB interface: A novel target for stapled peptides (273 visite)
De Paola I, Pirone L, Palmieri M, Balasco N, Esposito L, Russo L, Mazza D, Di Marcotullio L, Di Gaetano S, Malgieri G, Vitagliano L, Pedone E, Zaccaro L
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2015 Apr 7; 10(4): e0121149-e0121149.
Impact Factor: 3.057
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* Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam (224 visite)
Mercurio FA, Di Natale C, Pirone L, Scognamiglio PL, Marasco D, Pedone EM, Saviano M, Leone M
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-4227linking), 2015; 16(11): 1629-1636.
Impact Factor: 2.85
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* The identification of a novel Sulfolobus islandicus CAMP-like peptide points to archaeal microorganisms as cell factories for the production of antimicrobial molecules (203 visite)
Notomista E, Falanga A, Fusco S, Pirone L, Zanfardino A, Galdiero S, Varcamonti M, Pedone E, Contursi P
Microb Cell Fact (ISSN: 1475-2859), 2015; 14(1): N/D-N/D.
Impact Factor: 3.744
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* Functional and structural characterization of protein disulfide oxidoreductase from Thermus thermophilus HB27 (191 visite)
Pedone E, Fiorentino G, Pirone L, Contursi P, Bartolucci S, Limauro D
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic), 2014 Jul; 18(4): 723-731.
Impact Factor: 2.306
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* Molecular recognition of Cullin3 by KCTDs: Insights from experimental and computational investigations (167 visite)
Balasco N, Pirone L, Smaldone G, Di Gaetano S, Esposito L, Pedone E, Vitagliano L
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014 Jul; 1844(7): 1289-1298.
Impact Factor: 4.882
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* Sulfolobus solfataricus thiol redox puzzle: characterization of an atypical protein disulfide oxidoreductase (194 visite)
Limauro D, De Simone G, Pirone L, Bartolucci S, D'Ambrosio K, Pedone E
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic), 2014 Mar; 18(2): 219-228.
Impact Factor: 2.306
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* Structural and functional studies of Stf76 from the Sulfolobus islandicus plasmid-virus pSSVx: a novel peculiar member of the winged helix-turn-helix transcription factor family (154 visite)
Contursi P, Farina B, Pirone L, Fusco S, Russo L, Bartolucci S, Fattorusso R, Pedone E
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962), 2014; 42(9): 5993-6011.
Impact Factor: 9.112
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* A biophysical characterization of the folded domains of KCTD12: insights into interaction with the GABA(B2) receptor (154 visite)
Correale S, Esposito C, Pirone L, Vitagliano L, Di Gaetano S, Pedone E
Journal Of Molecular Recognition (ISSN: 0952-3499, 0952-2349), 2013 Oct; 26(10): 488-495.
Impact Factor: 2.337
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* Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates (178 visite)
Diana D, Smaldone G, De Antonellis P, Pirone L, Carotenuto M, Alonzi A, Di Gaetano S, Zollo M, Pedone E, Fattorusso R
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Sep 9; 19(37): 12217-12220.
Impact Factor: 5.696
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* Molecular basis of the PED/PEA15 interaction with the C-terminal fragment of phospholipase D1 revealed by NMR spectroscopy (235 visite)
Farina B, Doti N, Pirone L, Malgieri G, Pedone E, Ruvo M, Fattorusso R
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Sep; 1834(8): 1572-1580.
Impact Factor: 3.191
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* Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction (261 visite)
Carotenuto M, Pedone E, Diana D, de Antonellis P, Džeroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2013 Mar 1; 3: 1351-1351.
Impact Factor: 5.078
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* Heterotypic Sam-Sam Association Between Odin-Sam1 And Arap3-Sam: Binding Affinity And Structural Insights (138 visite)
Mercurio FA, Marasco D, Pirone L, Scognamiglio PL, Pedone E, Pellecchia M, Leone M
Chembiochem (ISSN: 1439-4227, 1439-9422, 1439-7633), 2013 Jan 2; 14(1): 100-106.
Impact Factor: 2.92
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* Thermal and chemical stability of two homologous POZ/BTB domains of KCTD proteins characterized by a different oligomeric organization (211 visite)
Pirone L, Esposito C, Correale S, Graziano G, Di Gaetano S, Vitagliano L, Pedone E
Biomed Res Int (ISSN: 2314-6133, 2314-6141, 2314-6141electronic), 2013; 2013: 162674-162674.
Impact Factor: 1.579
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* Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor (160 visite)
Mercurio FA, Marasco D, Pirone L, Pedone E, Pellecchia M,  Leone M
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2012 Mar 13; 51(10): 2136-2145.
Impact Factor: 3.377
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* Design, synthesis and characterization of a peptide able to bind proteins of the KCTD family: implications for KCTD - cullin 3 recognition (195 visite)
Pirone L, Correale S, De Paola I, Zaccaro L, De Simone G, Vitagliano L, Pedone E, Di Gaetano S
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 May; 17(5): 373-376.
Impact Factor: 1.799
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* C68 from the Sulfolobus islandicus plasmid-virus pSSVx is a novel member of the AbrB-like transcription factor family (223 visite)
Contursi P, D'Ambrosio K, Pirone L, Pedone E, Aucelli T, She Q, De Simone G, Bartolucci S
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2011 Apr 1; 435(1): 157-166.
Impact Factor: 4.897
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* Molecular organization of the cullin E3 ligase adaptor KCTD11 (204 visite)
Correale S, Pirone L, Di Marcotullio L, De Smaele E, Greco A, Mazzà D, Moretti M, Alterio V, Vitagliano L, Di Gaetano S, Gulino A, Pedone E
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2011 Apr; 93(4): 715-724.
Impact Factor: 3.022
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (181 visite)
Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
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* NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites (285 visite)
Farina B, Pirone L, Russo L, Viparelli F, Doti N, Pedone C, Pedone E, Fattorusso R
Febs J (ISSN: 1742-4658, 1742-464x, 1742-4658electronic), 2010 Oct; 277(20): 4229-4240.
Impact Factor: 3.129
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* Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (139 visite)
Limauro D, Pedone E, Pirone L, Bartolucci S
Febs Journal (ISSN: 1742-464x), 2006 Feb; 273(4): 721-731.
Impact Factor: 3.033
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