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 | | Name | Rita Berisio | | Area | Research and Development | | Position | Senior Researcher | | Work site | Naples - Mezzocannone | | Address | Via Mezzocannone 16, 80134 Naples - Italy | | E-mail | rita.berisio unina.it | | Office phone | +39 081 2534507 | | Mobile phone | +39 349.441.50.22 |
| Research Areas ▼
Activities ▼
Curriculum ▼
Rita Berisio was born in 1972 in Naples, Italy. In 1995, she graduated in chemistry at the University of Naples Federico II (summa cum laude). From 1996 to 1998 she worked at the European Molecular Biology Lab in Hamburg and in 1999 she received her PhD at the University of Naples.
Since 2001, Rita Berisio is a permanent researcher at the
Institute of Biostructures and Bioimaging (IBB) of the Italian Research
National Council (CNR), in Naples, Italy. In 2002-2004 she joined the group of Prof. Ada Yonath, Chemistry
Nobel Prize in 2009, at the Max-Planck-Institute in Hamburg, Germany. Rita
Berisio has been awarded the prize of the Italian Crystallography Association
(AIC) in 2006 for her contribution to structural biology. Since 2002, Rita Berisio is Senior Researcher at the Institute
of Biostructures and Bioimaging (IBB) of the Italian Research National Council
(CNR), in Naples, Italy. Dr
Berisio is co-author of more than 110 publications on international journals (among
which Nat Struct Biol, Mol Cell, JACS, PNAS, Structure), book chapters, and one patent. She
has been Guest Editor of a number of journals and is member of the Editorial
Board of The Scientific World Journal. Dr. Berisio is Editorial Advisory Board Member of "Current Medicinal Chemistry". She has been responsible for Regional, National and International funding initiatives, eg: (i) Italian Ministry of Research, project PON03PE_00157.
Role: PI, 2014-2015, Title: “Smart Generation”
(ii) Indigo
Linking programme Italy-India-UK, funded by EU. Role: International Coordinator, 2015-2016. Title: “DRAT-
Drugs against Tuberculosis”
(iii) COST Action (European Cooperation in the field of Scientific and Technical Research) BM1003. Role: PI, 2010-2014 and Grant Holder 2010-2012. Title: “Microbial cell surface determinants of virulence as targets for new therapeutics in Cystic Fibrosis” (iv) Mizutani Foundation for Glycoscience. Role: International Coordinator, 2011-2012. Title: “Molecular mechanisms of defense response induced by chitin oligosaccharides” (v) Italian Research Council, Cooperation
project with Poland. Role: PI, 2014-2016. Title: “Structure and function of selected
enzymes with phage origin” (vi) Italian Ministry of Research. Role: PI, 2011-2012. Title: “Structural studies of key proteins in
the pathogenesis of M. tuberculosis” Research
interests 1. Elucidating the
structure and in vitro function of key proteins involved in human pathogenesis 2. Determining key
regulatory mechanisms of cell wall modelling in pathogenic bacteria by coupling
x-ray crystallography and biophysical techniques with computational methods and
biochemical assays 3. Elucidating structural and functional features of protein mediators of
host:pathogen interactions 4. Study of molecular biomarkers of tumor pathogenesis |
Bibliography ▼
<=2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 ALL YEARS
Sort by: date ▼▲ title ▲ ▼ journal ▲ ▼ authors ▲ ▼ impact factor ▲ ▼* Collagen-like proteins of pathogenic streptococci (21 views)Lukomski S, Bachert B, Squeglia F, Berisio R Mol Microbiol (ISSN: 1365-2958electronic, 0950-382xlinking), 2017; 103: 919-930.
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* The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of inflammation (20 views)Dennehy R, Romanò MF, Ruggiero A, Mohamed YF, Dignam SL, Mujica Troncoso C, Callaghan M, Valvano MA, Berisio R, Mcclean S Cell Microbiol (ISSN: 1462-5822electronic, 1462-5814linking), 2017; 19: N/D-N/D.
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* Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy (22 views)Majkowska-skrobek G, Latka A, Berisio R, Maciejewska B, Squeglia F, RomanoM, Lavigne R, Struve C, Drulis-kawa Z Viruses (ISSN: 1999-4915electronic, 1999-4915linking), 2016 Dec 01; 8(12): N/D-N/D.
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* Unique Footprint in the scl1. 3 Locus Affects Adhesion and Biofilm Formation of the Invasive M3-Type Group A Streptococcus (21 views)Bachert BA, Choi SJ, Lasala PR, Harper TI, Mcnitt DH, Boehm DT, Caswell CC, Ciborowski P, Keene DR, Flores AR, Musser JM, Squeglia F, Marasco D, Berisio R, Lukomski S Front Cell Infect Microbiol (ISSN: 2235-2988electronic, 2235-2988linking), 2016 Aug 31; 6: 90-90.
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* Identification of an OmpW homologue in Burkholderia pseudomallei, a protective vaccine antigen against melioidosis (21 views)Casey WT, Spink N, Cia F, Collins C, Romanò MF, Berisio R, Bancroft GJ, Mcclean S Vaccine (ISSN: 1873-2518electronic, 0264-410xlinking), 2016 May 17; 34(23): 2616-2621.
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* Generation and characterization of monoclonal antibodies against a cyclic variant of Hepatitis C Virus E2 epitope 412-422 (65 views) (PDF 35 views)Sandomenico A, Leonardi A, Berisio R, Sanguigno L, Foca G, Foca A, Ruggiero A, Doti N, Muscariello L, Barone D, Farina C, Owsianka A, Vitagliano L, Patel AH, Ruvo M J Virol (ISSN: 1098-5514electronic, 0022-538xlinking), 2016 Jan 27; 90(7): 3745-3759.
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* NMR Structure and Dynamics of the Resuscitation Promoting Factor RpfC Catalytic Domain (68 views)Maione V, Ruggiero A, Russo L, De Simone A, Pedone PV, Malgieri G, Berisio R, Isernia C Plos One (ISSN: 1932-6203electronic, 1932-6203linking), 2015 Nov 17; 10(11): e0142807-e0142807.
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* A Unique Set of the Burkholderia Collagen-Like Proteins Provides Insight into Pathogenesis, Genome Evolution and Niche Adaptation, and Infection Detection (60 views)Bachert BA, Choi SJ, Snyder AK, Rio RV, Durney BC, Holland LA, Amemiya K, Welkos SL, Bozue JA, Cote CK, Berisio R, Lukomski S Plos One (ISSN: 1932-6203electronic, 1932-6203linking), 2015 Sep 10; 10(9): e0137578-e0137578.
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* A product of RpfB and RipA joint enzymatic action promotes the resuscitation of dormant mycobacteria (51 views)Nikitushkin VD, Demina GR, Shleeva MO, Guryanova SV, Ruggiero A, Berisio R, Kaprelyants AS Febs J (ISSN: 1742-4658electronic, 1742-464xlinking), 2015 Apr 3; 282(13): 2500-2511.
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* Chemistry of lipid a: At the heart of innate immunity (105 views) (PDF 110 views)Molinaro A, Holst O, Lorenzo FD, Callaghan M, Nurisso A, D'Errico G, Zamyatina A, Peri F, Berisio R, Jerala R, Jiménez-Barbero J, Silipo A, Martín-Santamarí S Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Jan 7; 21(2): 500-519.
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* Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis (62 views)Calvanese L, Falcigno L, Maglione C, Marasco D, Ruggiero A, Squeglia F, Berisio R, D'Auria G Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Jul; 101(7): 712-719.
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* Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo (57 views)Romanò MF, Van De Weerd R, Brouwer FCC, Roviello GN, Lacroix R, Sparrius M, Van Den Brink-van Stempvoort G, Maaskant JJ, Van Der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R Structurestructure (ISSN: 0969-2126, 1878-4186), 2014 May 6; 22(5): 719-730.
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* Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization (83 views)Hayafune M, Berisio R, Marchetti R, Silipo A, Kayama M, Desaki Y, Arima S, Squeglia F, Ruggiero A, Tokuyasu K, Molinaro A, Kaku H, Shibuya N Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2014 Jan 21; 111(3): E404-E404.
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* Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides (51 views)Cantisani M, Falanga A, Incoronato N, Russo L, De Simone A, Morelli G, Berisio R, Galdiero M, Galdiero S J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2013 Nov 14; 56(21): 8366-8376.
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* Structures of free and inhibited forms of the L, D-transpeptidase LdtMt1 from Mycobacterium tuberculosis (54 views)Correale S, Ruggiero A, Capparelli R, Pedone E, Berisio R Acta Crystallogr Sect D Biol Crystallogr Acta Crystallographica Section D Biological Crystallography (ISSN: 0907-4449), 2013 Sep; 69(Pt9): 1697-1706.
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* Editorial (51 views)Berisio R Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1011-1012.
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* Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination (54 views)Esposito C, Cantisani M, D'Auria G, Falcigno L, Pedone E, Galdiero S, Berisio R Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2012 Mar 23; 586(6): 659-667.
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* Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy (39 views)Squeglia F, Marchetti R, Ruggiero A, Lanzetta R, Marasco D, Dworkin J, Petoukhov M, Molinaro A, Berisio R, Silipo A J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2011 Dec 28; 133(51): 20676-20679.
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* Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (58 views)Ruggiero A, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS, Berisio R, D'Auria S, Vitagliano L Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2011 Nov 1; 67(11): 1462-1465.
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* Dynamical properties of cold shock protein A from Mycobacterium tuberculosis (50 views)D'Auria G, Esposito C, Falcigno L, Calvanese L, Iaccarino E, Ruggiero A, Pedone C, Pedone E, Berisio R Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic), 2010 Nov 26; 402(4): 693-698.
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* Expression, purification, crystallization and preliminary x-ray crystallographic analysis of the peptidoglycan binding region of the ser/thr kinase PrkC from staphylococcus aureus (42 views)Ruggiero A, Squeglia F, Izzo V, Silipo A, Vitagliano L, Molinaro A, Berisio R Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2010 Oct; 17(10): 1296-1299.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (41 views)Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
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* The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves (35 views)Severino V, Chambery A, Di Maro A, Marasco D, Ruggiero A, Berisio R, Giansanti F, Ippoliti R, Parente A Mol Biosyst (ISSN: 1742-206x), 2010; 6(3): 570-579.
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* Comment on Microfibrillar structure of type i collagen in situ by Orgel et al. (2006), Proc. Natl Acad. Sci. USA, 103, 9001-9005 (33 views)Okuyama K, Baechinger HP, Mizuno K, Boudko S, Engel J, Berisio R, Vitagliano L Acta Crystallogr Sect D Biol Crystallogr Acta Crystallographica Section D Biological Crystallography (ISSN: 0907-4449), 2009 Sep; 65(9): 1007-1008.
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* Ribosome's mode of function: Myths, facts and recent results (32 views)Wekselman I, Davidovich C, Agmon I, Zimmerman E, Rozenberg H, Bashan A, Berisio R, Yonath A J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 122-130.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (30 views)Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
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* 23S rRNA 2058A→G alteration mediates ketolide resistance in combination with deletion in L22 (28 views)Berisio R, Corti N, Pfister P, Yonath A, Böttger EC Antimicrobial Agents And Chemotherapy (ISSN: 0066-4804, 1098-6596), 2006 Nov; 50(11): 3816-3823.
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* The effect of the osmolyte trimethylamine N-oxide on the stability of the prion protein at low pH (26 views)Granata V, Palladino P, Tizzano B, Negro A, Berisio R, Zagari A Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2006 Jun 15; 82(3): 234-240.
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* Polyproline helices in protein structures: A statistical survey (36 views)Berisio R, Loguercio S, De Simone A, Zagari A, Vitagliano L Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2006; 13(8): 847-854.
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* A crevice adjoining the ribosome tunnel: Hints for cotranslational folding (59 views)Amit M, Berisio R, Baram D, Harms J, Bashan A, Yonath A Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2005 Jun 13; 579(15): 3207-3213.
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* Productive And Non-Productive Binding Of Polyketides To The Ribosome Large Subunit (24 views)Berisio R, Amit M, Baram D, Harms J, Bashan A, Hansen H, Schluenzen F, Yonath A Acta Crystallogr D Biol Crystallogr, 2005; N/D: 61-61.
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* Ribosomal crystallography: A flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism (26 views)Agmon I, Amit M, Auerbach T, Bashan A, Baram D, Bartels H, Berisio R, Greenberg I, Harms J, Hansen HAS, Kessler M, Pyetan E, Schluenzen F, Sittner A, Yonath A, Zarivach R Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2004 Jun 1; 567(1): 20-26.
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* Functional aspects of ribosomal architecture: Symmetry, chirality and regulation (27 views)Zarivach R, Bashan A, Berisio R, Harms J, Auerbach T, Schluenzen F, Bartels H, Baram D, Pyetan E, Sittner A, Amit M, Hansen HAS, Kessler M, Liebe C, Wolff A, Agmon I, Yonath A J Phys Org Chem (ISSN: 0894-3230), 2004; 17(11): 901-912.
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* Ribosomal crystallography: Peptide bond formation and its inhibition (44 views)Bashan A, Zarivach R, Schluenzen F, Agmon I, Harms J, Auerbach T, Baram D, Berisio R, Bartels H, Hansen HAS, Fucini P, Wilson D, Peretz M, Kessler M, Yonath A Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003 Sep; 70(1): 19-41.
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* Structural insight into the antibiotic action of telithromycin against resistant mutants (33 views)Berisio R, Harms J, Schluenzen F, Zarivach R, Hansen HAS, Fucini P, Yonath A J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530), 2003 Jul; 185(14): 4276-4279.
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* On Peptide Bond Formation, Translocation, Nascent Protein Progression And The Regulatory Properties Of Ribosomes. Derived On 20 October 2002 At The 28th Febs Meeting In Istanbul (22 views)Agmon I, Auerbach T, Baram D, Bartels H, Bashan A, Berisio R, Fucini P, Hansen HA, Harms J, Kessler M, Peretz M, Schluenzen F, Yonath A, Zarivach R Chembiochem, 2003 Jun; 270(12): 2543-2556.
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* Structural insight into the role of the ribosomal tunnel in cellular regulation (28 views)Berisio R, Schluenzen F, Harms J, Bashan A, Auerbach T, Baram D, Yonath A Nat Struct Biol (ISSN: 1072-8368), 2003 May; 10(5): 366-370.
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* Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression (59 views)Bashan A, Agmon I, Zarivach R, Schluenzen F, Harms J, Berisio R, Bartels H, Franceschi F, Auerbach T, Hansen HAS, Kossoy E, Kessler M, Yonath A Molecular Cell (ISSN: 1097-2765, 1097-4164), 2003 Jan; 11(1): 91-102.
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* Methods Of Growing Crystals Of Free, Antibiotic-Complexed, And Substrate-Complexed Large Ribosomal Subunits, And Methods Of Rational Designing Or Identifying Antibiotics Using Structure Coordinate Data Derived From Such Crystals (35 views)Yonath A, Bashan A, Zarivach R, Franceschi F, Schluenzen F, Harms J, Albrecht R, Berisio R International Publication Number, 2003; N/D: N/D-N/D.
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* Atomic resolution structures of ribonuclease A at six pH values (54 views)Berisio R, Sica F, Lamzin VS, Wilson KS, Zagari A, Mazzarella L Acta Crystallogr Sect D Biol Crystallogr Acta Crystallographica Section D Biological Crystallography (ISSN: 0907-4449), 2002; 58(3): 441-450.
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* Atomic resolution structure of a mutant of the spectrin SH3 domain (35 views)Berisio R, Viguera A, Serrano L, Wilmanns M Acta Crystallogr Sect D Biol Crystallogr Acta Crystallographica Section D Biological Crystallography (ISSN: 0907-4449), 2001 Feb; 57(2): 337-340.
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* Depletion Zone Around Sedimenting Protein Crystals In Microgravity (34 views)Carotenuto L, Cartwright J, Otálora F, Garcia-ruiz J, Castagnolo D, Piccolo C, Berisio R, Vitagliano L, Mazzarella L, Zagari A Esa Journal, 2001; 454: 323-329.
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Effects of microgravity on the crystal quality of a collagen-like polypeptide (42 views)Berisio R, Vitagliano L, Sorrentino G, Carotenuto L, Piccolo C, Mazzarella L, Zagari A Acta Crystallogr Sect D Biol Crystallogr Acta Crystallographica Section D Biological Crystallography (ISSN: 0907-4449), 2000 Jan; 56(1): 55-61.
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Biomolecule crystallisation in microgravity (34 views)Carotenuto L, Castagnolo D, Piccolo C, Berisio R, Vitagliano L, Mazzarella L, Zagari A Eur Space Agency Spec Publ Esa Sp (ISSN: 0379-6566), 2000; (454I): 437-443.
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Protein titration in the crystal state (34 views)Berisio R, Lamzin VS, Sica F, Wilson KS, Zagari A, Mazzarella L J Mol Biol Journal Of Molecular Biology (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Oct 1; 292(4): 845-854.
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X-ray crystallographic determination of a collagen-like peptide with the repeating sequence (Pro-Pro-Gly) (61 views)Kramer RZ, Vitagliano L, Bella J, Berisio R, Mazzarella L, Brodsky B, Zagari A, Berman HM J Mol Biol Journal Of Molecular Biology (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1998 Jul 24; 280(4): 623-638.
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Protein Crystal Growth In The Advance Protein Crystallisation Facility On The Lms Mission: A Comparison Of Sulfolobus Solfataricus Alchool Dehydrogenase Crystals Grown On The Ground And In Microgravity (26 views) Esposito L, Sica F, Sorrentino G, Berisio R, Carotenuto L, Giordano A, Raia C, Rossi M, Lamzin VS, Willson KS, Zagari A Acta Crystallogr D Biol Crystallogr, 1998; 54: 386-390.
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Protein crystal growth in the advanced protein crystallization facility on the LMS mission: A comparison of Sulfolobus solfataricus alcohol dehydrogenase crystals grown on the ground and in microgravity (48 views)Esposito L, Sica F, Sorrentino G, Berisio R, Carotenuto L, Giordano A, Raia CA, Rossi M, Lamzin VS, Wilson KS, Zagari A Acta Crystallogr Sect D Biol Crystallogr Acta Crystallographica Section D Biological Crystallography (ISSN: 0907-4449), 1998; 54(3): 386-390.
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120 Records ( 118 excluding Abstracts and Conferences). Total impact factor: 464.742 ( 460.124 excluding Abstracts and Conferences). Total 5-year impact factor: 464.345 ( 459.34 excluding Abstracts and Conferences).
Your bibliography query: [author] BERISIO_R
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