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 | | Name | Luca Domenico D'Andrea | | Area | Research and Development | | Position | Researcher | | Work site | Naples - Mezzocannone | | Address | Via Mezzocannone 16, 80134 Naples - Italy | | E-mail | ldandrea unina.it | | Office phone | +39 081 253.66.79 |
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Curriculum ▼
Luca D'Andrea obtained the Degree in Chemistry (Summa cum Laude) at the University of Naples "Federico II" (Italy) in 1995, the Ph. D. in Chemistry at the University of Naples "Federico II" in 1999. Then he was Postdoctoral associate at Department of Molecular Biophysics and Biochemistry Yale University USA under the supervision of Prof. L. Regan. Since 2001 Luca D'Andrea is Research Scientist at the Istituto di Biostrutture e Bioimmagini of CNR. The scientific interests of Dr. D'Andrea are in the area of peptide and protein chemistry. The research activity has focused on the design, synthesis and characterization of peptide/peptidomimetics and small proteins mainly targeting protein? protein interaction. The designed molecules could find application as therapeutic/diagnostic agents or as molecular tools to modulate biological processes. Recently, the scientific activity also includes the analysis of folding in peptides and protein motif and the use of expressed protein ligation for biophysical and chemical biology applications. Dr. DAndrea has been recipient of regional, national (PRIN) and international grants (HFSP). He received in 1999 a NATO-CNR Advanced Fellowship, and a CNR award for the research activity in 2005. |
Bibliography ▼
<=2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 ALL YEARS
Sort by: date ▼▲ title ▲ ▼ journal ▲ ▼ authors ▲ ▼ impact factor ▲ ▼* Binding studies of antimicrobial peptides to Escherichia coli cells (6 views)Avitabile C, D'Andrea LD, Saviano M, Olivieri M, Cimmino A, Romanelli A Biochem Biophys Res Commun (ISSN: 1090-2104electronic, 0006-291xlinking), 2016 Sep 09; 478(1): 149-153.
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* Miniaturizing VEGF: Peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic response (6 views)De Rosa L, Finetti F, Diana D, Di Stasi R, Auriemma S, Romanelli A, Fattorusso R, Ziche M, Morbidelli L, D'Andrea LD Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2016 Aug 08; 6: 31295-31295.
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* fac-[Re(H2O)3(CO)3]+ Complexed with Histidine and Imidazole in aqueous solution: Speciation, Affinity and Binding Features (11 views)De Tommaso G, Celentano V, Malgieri G, Fattorusso R, Romanelli A, D'Andrea LD, Iuliano M, Isernia C Chemistry Select, 2016 Aug; 1,Issue13: 3739-3744.
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* 1, 2, 3-Triazole Bridge as Conformational Constrain in beta-Hairpin Peptides: Analysis of Hydrogen-Bonded Positions (6 views)Celentano V, Diana D, Di Salvo C, De Rosa L, Romanelli A, Fattorusso R, D'Andrea LD Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2016 Apr 11; 22(16): 5534-5537.
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* Long range Trp-Trp interaction initiates the folding pathway of a pro-angiogenic beta-hairpin peptide (6 views)Diana D, De Rosa L, Palmieri M, Russomanno A, Russo L, La Rosa C, Milardi D, Colombo G, D'Andrea LD, Fattorusso R Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2015 Nov 25; 5: 16651-16651.
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* Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion (55 views)Pignataro G, Ziaco B, Tortiglione A, Gala R, Cuomo O, Vinciguerra A, Lapi D, Mastantuono T, Anzilotti S, D'Andrea LD, Pedone C, Di Renzo G, Annunziato L, Cataldi M Acs Chem Neurosci (ISSN: 1948-7193electronic, 1948-7193linking), 2015 Sep 16; 6(9): 1517-1525.
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* Functional Binding Surface Of A Beta-Hairpin Vegf Receptor Targeting Peptide Determined By Nmr Spectroscopy In Living Cells (68 views)Diana D, Russomanno A, De Rosa L, Di Stasi R, Capasso D, Di Gaetano S, Romanelli A, Russo L, D'Andrea LD, Fattorusso R Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Jan 2; 21(1): 91-95.
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* Probing the molecular origin of native-state flexibility in repeat proteins (118 views)Cohen SS, Riven I, Cortajarena AL, De Rosa L, D'Andrea LD, Regan L, Haran G J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2015; 137(32): 10367-10373.
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* Compounds modulators of VEGF activity and uses thereof (38 views)D'Andrea LD, Pedone C, Turco MC Patents Official Gazette Of The United States Patent And Trademark Office (ISSN: 0098-1133), 2014 Jun 3; N/D: N/D-N/D.
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* Design, Structural And Biological Characterization Of A Vegf Inhibitor Beta-Hairpin-Constrained Peptide (66 views)De Rosa L, Diana D, Basile A, Russomanno A, Isernia C, Turco MC, Fattorusso R, D'Andrea LD Eur J Med Chem (ISSN: 0223-5234, 1768-3254), 2014; 73: 210-216.
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* Design, structural and functional characterization of a Temporin-1b analog active against Gram-negative bacteria (66 views)Avitabile C, Netti F, Orefice G, Palmieri M, Nocerino N, Malgieri G, D'Andrea LD, Capparelli R, Fattorusso R, Romanelli A Biochim Biophys Acta (ISSN: 0304-4165, 0006-3002, 0925-4439), 2013 Jun; 1830(6): 3767-3775.
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* Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis (93 views)Finetti F, Basile A, Capasso D, Di Gaetano S, Di Stasi R, Pascale M, Turco CM, Ziche M, Morbidelli L, D'Andrea LD Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2012 Sep 1; 84(3): 303-311.
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* Targeting pre-miRNA by peptide nucleic acids: a new strategy to interfere in the miRNA maturation (66 views)Avitabile C, Saviano M, D'Andrea LD, Bianchi N, Fabbri E, Brognara E, Gambari R, Romanelli A Artif Dna Pna Xnaartificial Dna Pna & Xna (ISSN: 1949-9096, 1949-0968, 1949-095x), 2012 Apr; 3(2): 88-96.
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* Apolipoprotein A-I (ApoA-I) mimetic peptide P2a by restoring cholesterol esterification unmasks ApoA-I anti-inflammatory endogenous activity in vivo (64 views)Bucci M, Cigliano L, Vellecco V, D'Andrea LD, Ziaco B, Rossi A, Sautebin L, Carlucci A, Abrescia P, Pedone C, Ianaro A, Cirino G J Pharmacol Exp Ther Journal Of Pharmacology And Experimental Therapeutics (ISSN: 1521-0103, 0022-3565), 2012 Mar; 340(3): 716-722.
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* beta-Hairpin stabilization through an interstrand triazole bridge (48 views)Celentano V, Diana D, De Rosa L, Romanelli A, Fattorusso R, D'Andrea LD Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2012 Jan 18; 48(5): 762-764.
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* Beta-Hairpin Peptide That Targets Vascular Endothelial Growth Factor (vegf) Receptors: Design, Nmr Characterization, And Biological Activity (85 views)Diana D, Basile A, De Rosa L, Di Stasi R, Auriemma S, Arra C, Pedone C, Turco MC, Fattorusso R, D'Andrea LD J Biol Chem Journal Of Biological Chemistry (ISSN: 1083-351x, 0021-9258), 2011 Dec 2; 286(48): 41680-41691.
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* Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo (59 views)Basile A, Del Gatto A, Diana D, Di Stasi R, Falco A, Festa M, Rosati A, Barbieri A, Franco R, Arra C, Pedone C, Fattorusso R, Turco MC, D'Andrea LD J Med Chem (ISSN: 1520-4804, 0022-2623, 0022-2623print), 2011 Mar 10; 54(5): 1391-1400.
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* Biochemical and Structural Analysis of the Binding Determinants of a Vascular Endothelial Growth Factor Receptor Peptidic Antagonist (41 views)Gautier B, Goncalves V, Diana D, Di Stasi R, Teillet F, Lenoir C, Huguenot F, Garbay C, Fattorusso R, D'Andrea LD, Vidal M, Inguimbert N J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jun 10; 53(11): 4428-4440.
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* Copper binds the carboxy-terminus of trefoil protein 1 (TFF1), favoring its homodimerization and motogenic activity (57 views)Tosco A, Monti MC, Fontanella B, Montefusco S, D'Andrea LD, Ziaco B, Baldantoni D, Rio MC, Marzullo L Cell Mol Life Sci Cellular And Molecular Life Sciences (ISSN: 1420-9071electronic, 1420-682xlinking), 2010 Jun; 67(11): 1943-1955.
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* Structural analysis of a helical peptide unfolding pathway (49 views)Diana D, Ziaco B, Scarabelli G, Pedone C, Colombo G, D'Andrea LD, Fattorusso R Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2010 May 10; 16(18): 5400-5407.
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* PNA zipper as a dimerization tool: development of a bZip mimic (49 views)Pensato S, Renda M, Leccia F, Saviano M, D'Andrea LD, Pedone C, Pedone PV, Romanelli A Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 May; 93(5): 434-441.
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* VEGFR1(D2) in drug discovery: Expression and molecular characterization (47 views)Di Stasi R, Diana D, Capasso D, Palumbo R, Romanelli A, Pedone C, Fattorusso R, D'Andrea LD Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010; 94(6): 800-809.
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* In vivo properties of the proangiogenic peptide QK (44 views)Santulli G, Ciccarelli M, Palumbo G, Campanile A, Galasso G, Ziaco B, Altobelli GG, Cimini V, Piscione F, D'Andrea LD, Pedone C, Trimarco B, Iaccarino G J Transl Med Journal Of Translational Medicine (ISSN: 1479-5876, 1479-5876electronic), 2009 Jun 8; 7: 41-41.
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* Calcium-calmodulin-dependent kinase II (CaMKII) mediates insulin-stimulated proliferation and glucose uptake (42 views)Illario M, Monaco S, Cavallo AL, Esposito I, Formisano P, D'Andrea LD, Cipolletta E, Trimarco B, Fenzi G, Rossi G, Vitale M Cell Signal Cellular Signalling (ISSN: 0898-6568), 2009 May; 21(5): 786-792.
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* Relevance of the amino acid conversions L144R (Zaragoza) and L159P (Zavalla) in the apolipoprotein A-I binding site for haptoglobin (40 views)Cigliano L, D'Andrea LD, Maresca B, Serino M, Carlucci A, Salvatore A, Spagnuolo MS, Scigliuolo G, Pedone C, Abrescia P Biol Chem Biological Chemistry (ISSN: 1431-6730, 1437-4315), 2008 Nov; 389(11): 1421-1426.
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* A vascular endothelial growth factor mimetic accelerates gastric ulcer healing in an iNOS-dependent manner (63 views)Dudar GK, D'Andrea LD, Di Stasi R, Pedone C, Wallace JL Am J Physiol Gastrointest Liver Physiol American Journal Of Physiology Gastrointestinal And Liver Physiology (ISSN: 0193-1857), 2008 Sep; 295(2): G374-G374.
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* The unusual helix stability of a VEGF mimetic peptide (39 views)Diana D, Ziaco B, Colombo G, Scarabelli G, Romanelli A, Pedone C, Fattorusso R, D'Andrea LD J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
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* Semisynthesis of dimeric proteins by expressed protein ligation (30 views)Ziaco B, Pensato S, D'Andrea LD, Benedetti E, Romanelli A Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2008 May 15; 10(10): 1955-1958.
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* In vivo and in vitro characterization of CCK8 bearing a histidine-based chelator labeled with Tc-99m-tricarbonyl (107 views)D'Andrea LD, Testa I, Panico M, Di Stasi R, Carac C, Tarallo L, Arra C, Barbieri A, Romanelli A, Aloj L Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 90(5): 707-712.
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* Structural determinants of the unusual helix stability of a de novo engineered vascular endothelial growth factor (VEGF) mimicking peptide (52 views)Diana D, Ziaco B, Colombo G, Scarabelli G, Romanelli A, Fedone C, Fattorusso R, D'Andrea LD Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2008; 14(14): 4164-4166.
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* A novel type of zinc finger DNA binding domain in the Agrobacterium tumefaciens transcriptional regulator Ros (40 views)Esposito S, Baglivo I, Malgieri G, Russo L, Zaccaro L, D'Andrea LD, Mammucari M, Di Blasio B, Isernia C, Fattorusso R, Pedone PV Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Sep 29; 45(34): 10394-10405.
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* Peptide-based molecules in angiogenesis (67 views)D'Andrea LD, Del Gatto A, Pedone C, Benedetti E Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2006 Feb; 67(2): 115-126.
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* Peptides reproducing the ApoA-I 141-164 region: Studies on Hpt recognition (28 views)D'Andrea LD, Spagnuolo M, De Stefano A, Morra M, Carlucci A, Del Gatto A, Caso P, Pedone C, Abrescia P, Benedetti E Understanding Biology Using Peptides, 2006; N/D: N/D-N/D.
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* Activity of anchored human matrix metalloproteinase-1 catalytic domain on Au(111) surfaces monitored by ESI-MS (46 views)Grasso G, D'Agata R, Rizzarelli E, Spoto G, D'Andrea LD, Pedone C, Picardi A, Romanelli A, Fragai M, Yeo KJ J Mass Spectrom Journal Of Mass Spectrometry (ISSN: 1076-5174, 1096-9888), 2005 Dec; 40(12): 1565-1571.
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* Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide (69 views)D'Andrea LD, Iaccarino G, Fattorusso R, Sorriento D, Carannante C, Capasso D, Trimarco B, Pedone C Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2005 Oct 4; 102(40): 14215-14220.
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* Assignment of the binding site for haptoglobin on apolipoprotein A-I (51 views)Spagnuolo MS, Cigliano L, D'Andrea LD, Pedone C, Abrescia P J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2005 Jan 14; 280(2): 1193-1198.
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* TPR proteins: the versatile helix (41 views)D'Andrea LD, Regan L Trends Biochem Sci Trends In Biochemical Sciences (ISSN: 0968-0004), 2003 Dec; 28(12): 655-662.
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* Design of stable α-helical arrays from an idealized TPR motif (28 views)Main ERG, Xiong Y, Cocco MJ, D'Andrea LD, Regan L Structurestructure (ISSN: 0969-2126, 1878-4186), 2003; 11(5): 497-508.
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A novel super-potent neurokinin A receptor antagonist containing dehydroalanine (42 views)Lombardi A, D'Agostino B, Nastri F, D'Andrea LD, Filippelli A, Falciani M, Rossi F, Pavone V Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894xprint, 0960-894xlinking), 1998 May 19; 8(10): 1153-1156.
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Miniaturized hemoproteins (34 views)Nastri F, Lombardi A, D'Andrea LD, Sanseverino M, Maglio O, Pavone V Biopolymers (ISSN: 0006-3525print, 0006-3525linking, 1097-0282electronic), 1998; 47(1): 5-22.
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Solution conformational preferences of a peptidic analogue of a natural macrolide (49 views)D'Andrea LD, Mazzeo M, Isernia C, Rossi F, Saviano M, Gallo P, Paolillo L, Pedone C Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1997; 42(3): 349-361.
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63 Records ( 58 excluding Abstracts and Conferences). Total impact factor: 235.309 ( 228.971 excluding Abstracts and Conferences). Total 5-year impact factor: 228.929 ( 222.947 excluding Abstracts and Conferences).
Your bibliography query: [author] D\'ANDREA_LD
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