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 | | Name | Stefania Galdiero | | Area | Research and Development | | Position | Associated Scientist | | Work site | Naples - Mezzocannone | | Address | Via Mezzocannone 16, 80134 Naples - Italy | | E-mail | sgaldier unina.it | | Office phone | +39 081 2534503 |
| Curriculum ▼
Dr Galdiero completed her doctorate in Chemistry with the study of peptides chemistry at the University of Naples Federico II in 1998. From 1986 to 1987 she has carried out research activities at the Columbia University of New York, working on the structure of alpha-hemolysin from S. aureus and its interactions with phospholipids under the supervision of Dr. Eric Gouaux. From 1999 she has been Researcher of the Science Faculty of the University of Napoli "Federico II" and Professor of General and Inorganic Chemistry, Stechiometry and Inorganic Chemistry Laboratory for undergraduates students. She is member of Istituto di Biostrutture e Bioimmagini (IBB) of the National Research Council of Italy and of Centro di Competenza in Diagnostica e Farmaceutica Molecolari (CRdC DFM). The main interest of her research activities are focussed on identifying and defining at a molecular level new diagnostic and therapeutic targets; finding new bioactive ligands able to modulate the activity of the identified targets; improving the transport, specificity, biodistribution, toxicity of identified active compounds by the design of new drug delivery molecular systems. The most recent topics of research concern: 1) biological activity of structural components of Gram-negative bacteria surface; 2) analysis of enveloped viruses penetration mechanism; 3) design of novel molecules that may be used as antimicrobials; 3) design of vaccines; 4) intracellular delivery. Dr Galdiero is author of more than 45 articles on international peer-reviewed journals. |
Bibliography ▼
<=2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 ALL YEARS
Sort by: date ▼▲ title ▲ ▼ journal ▲ ▼ authors ▲ ▼ impact factor ▲ ▼* Design and activity of a cyclic mini-beta-defensin analog: a novel antimicrobial tool (46 views)Scudiero O, Nigro E, Cantisani M, Colavita I, Leone M, Mercurio FA, Galdiero M, Pessi A, Daniele A, Salvatore F, Galdiero S Int J Nanomedicine (ISSN: 1178-2013electronic, 1176-9114linking), 2015 Oct 15; 10: 6523-6539.
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* Investigating the inclusion properties of aromatic amino acids complexing beta-cyclodextrins in model peptides (39 views)Caso JV, Russo L, Palmieri M, Malgieri G, Galdiero S, Falanga A, Isernia C, Iacovino R Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015; N/D: N/D-N/D.
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* Structural insights into and activity analysis of the antimicrobial peptide myxinidin (56 views)Cantisani M, Finamore E, Mignogna E, Falanga A, Nicoletti GF, Pedone C, Morelli G, Leone M, Galdiero M, Galdiero S Antimicrobial Agents And Chemotherapy (ISSN: 1098-6596, 0066-4804), 2014 Sep; 58(9): 5280-5290.
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* Exploitation of viral properties for intracellular delivery (63 views)Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2014 Jul; 20(7): 468-478.
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* Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides (51 views)Cantisani M, Falanga A, Incoronato N, Russo L, De Simone A, Morelli G, Berisio R, Galdiero M, Galdiero S J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2013 Nov 14; 56(21): 8366-8376.
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* Structure-Activity Relations of Myxinidin, an Antibacterial Peptide Derived from the Epidermal Mucus of Hagfish (75 views)Cantisani M, Leone M, Mignogna E, Kampanaraki K, Falanga A, Morelli G, Galdiero M, Galdiero S Antimicrobial Agents And Chemotherapy (ISSN: 0066-4804, 1098-6596), 2013 Nov; 57(11): 5665-5673.
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* Peptide-Lipid Interactions: Experiments and Applications (62 views)Galdiero S, Falanga A, Cantisani M, Vitiello M, Morelli G, Galdiero M Int J Mol Sci (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2013 Sep; 14(9): 18758-18789.
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* Chimeric beta-defensin analogs, including the novel 3NI analog, display salt-resistant antimicrobial activity and lack toxicity in human epithelial cell lines (65 views)Scudiero O, Galdiero S, Nigro E, Del Vecchio L, Di Noto R, Cantisani M, Colavita I, Galdiero M, Cassiman JJ, Daniele A, Pedone C, Salvatore F Antimicrobial Agents And Chemotherapy (ISSN: 1098-6596, 0066-4804), 2013 Apr; 57(4): 1701-1708.
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* Peptide inhibitors against herpes simplex virus infections (86 views)Galdiero S, Falanga A, Tarallo R, Russo L, Galdiero E, Cantisani M, Morelli G, Galdiero M J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Mar; 19(3): 148-158.
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* gH625 is a viral derived peptide for effective delivery of intrinsically disordered proteins (75 views)Smaldone G, Falanga A, Capasso D, Guarnieri D, Correale S, Galdiero M, Netti PA, Zollo M, Galdiero S, Di Gaetano S, Pedone E Int J Nanomedicine (ISSN: 1178-2013, 1176-9114, 1178-2013electronic), 2013; 8: 2555-2565.
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* Microbe-Host Interactions: Structure and Role of Gram-Negative Bacterial Porins (56 views)Galdiero S, Falanga A, Cantisani M, Tarallo R, della Pepa ME, D'Oriano V, Galdiero M Curr Protein Pept Sci (ISSN: 1389-2037), 2012 Dec; 13(8): 843-854.
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* Structure and Orientation of the gH625-644 Membrane Interacting Region of Herpes Simplex Virus Type 1 in a Membrane Mimetic System (30 views)Galdiero S, Russo L, Falanga A, Cantisani M, Vitiello M, Fattorusso R, Malgieri G, Galdiero M, Isernia C Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2012 Apr 10; 51(14): 3121-3128.
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* Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination (54 views)Esposito C, Cantisani M, D'Auria G, Falcigno L, Pedone E, Galdiero S, Berisio R Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2012 Mar 23; 586(6): 659-667.
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* Biophysical Characterization and Membrane Interaction of the Two Fusion Loops of Glycoprotein B from Herpes Simplex Type I Virus (70 views)Falanga A, Tarallo R, Vitiello G, Vitiello M, Perillo E, Cantisani M, D'Errico G, Galdiero M, Galdiero S Plos One (ISSN: 1932-6203, 1932-6203electronic), 2012 Feb 23; 7(2): N/D-N/D.
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* Intracellular Delivery: Exploiting Viral Membranotropic Peptides (82 views)Galdiero S, Vitiello M, Falanga A, Cantisani M, Incoronato N, Galdiero M Current Drug Metabolism (ISSN: 1389-2002), 2012 Jan; 13(1): 93-104.
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* Peptides complementary to the active loop of porin P2 from Haemophilus influenzae modulate its activity (65 views)Cantisani M, Vitiello M, Falanga A, Finamore E, Galdiero M, Galdiero S Int J Nanomedicine (ISSN: 1178-2013, 1176-9114, 1178-2013electronic), 2012; 7: 2361-2371.
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* A peptide derived from herpes simplex virus type 1 glycoprotein H: membrane translocation and applications to the delivery of quantum dots (43 views)Falanga A, Vitiello MT, Cantisani M, Tarallo R, Guarnieri D, Mignogna E, Netti P, Pedone C, Galdiero M, Galdiero S Nanomedicine (ISSN: 1549-9642, 1549-9634), 2011 Dec; 7(6): 925-934.
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* Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease (46 views)D'Errico G, Ercole C, Lista M, Pizzo E, Falanga A, Galdiero S, Spadaccini R, Picone D Biochim Biophys Acta (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Dec; 1808(12): 3007-3015.
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* Clickable functionalization of liposomes with the gH625 peptide from herpes simplex virus type i for intracellular drug delivery (55 views)Tarallo R, Accardo A, Falanga A, Guarnieri D, Vitiello G, Netti P, D'Errico G, Morelli G, Galdiero S Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Nov 4; 17(45): 12659-12668.
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* Silver Nanoparticles as Potential Antiviral Agents (73 views)Galdiero S, Falanga A, Vitiello M, Cantisani M, Marra V, Galdiero M Molecules (ISSN: 1420-3049), 2011 Oct; 16(10): 8894-8918.
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* Novel synthetic, salt-resistant analogs of human beta-defensins 1 and 3 endowed with enhanced antimicrobial activity (68 views)Scudiero O, Galdiero S, Cantisani M, Di Noto R, Vitiello M, Galdiero M, Naclerio G, Cassiman JJ, Pedone C, Castaldo G, Salvatore F Antimicrobial Agents And Chemotherapy (ISSN: 1098-6596, 0066-4804), 2010 Jun; 54(6): 2312-2322.
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* Proteomic Analysis of Human U937 Cell Line Activation Mediated by Haemophilus influenzae Type b P2 Porin and Its Surface-Exposed Loop (26 views)Severino V, Chambery A, Vitiello M, Cantisani M, Galdiero S, Galdiero M, Malorni L, Di Maro A, Parente A J Proteome Res Journal Of Proteome Research (ISSN: 1535-3893), 2010 Feb; 9(2): 1050-1062.
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* Synthetic Analogs Of Human Beta-Defensins Display A More Effective Antimicrobial Activity Than Wild-Type Peptides (37 views)Scudiero O, Galdiero S, Cantisani M, Di Noto R, Galdiero M, D'Isanto M, Naclerio G, Pedone C, Castaldo G, Salvatore F Antimicrob Agents Chemother, 2010; 54: 2312-2322.
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* Viral fusion peptides induce several signal transduction pathway activations that are essential for interleukin-10 and beta-interferon production (28 views)Vitiello M, Finamore E, Falanga A, Raieta K, Cantisani M, Galdiero F, Pedone C, Galdiero M, Galdiero S Intervirology (ISSN: 1423-0100, 0300-5526), 2010; 53(6): 381-389.
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* Membrane fusion and fission: enveloped viruses (36 views)Falanga A, Cantisani M, Pedone C, Galdiero S Protein And Peptide Letters (ISSN: 1875-5305, 0929-8665), 2009 Jul; 16(7): 751-759.
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* Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein (54 views)Galdiero S, Falanga A, Vitiello M, Raiola L, Fattorusso R, Browne H, Pedone C, Isernia C, Galdiero M J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2008 Oct 31; 283(44): 29993-30009.
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* Peptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity (32 views)Galdiero S, Vitiello M, Falanga A, D'Isanto M, Cantisani M, Kampanaraki A, Benedetti E, Browne H, Galdiero M Peptides (ISSN: 0196-9781, 1873-5169electronic, 0196-9781linking), 2008 Sep; 29(9): 1461-1471.
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* The identification and characterization of fusogenic domains in herpes virus glycoprotein B molecules (40 views)Galdiero S, Vitiello M, D'Isanto M, Falanga A, Cantisani M, Browne H, Pedone C, Galdiero M Chembiochem (ISSN: 1439-7633, 1439-4227, 1439-7633electronic), 2008 Mar 25; 9(5): 758-767.
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* Evidence for a role of the membrane-proximal region of herpes simplex virus type 1 glycoprotein H in membrane fusion and virus inhibition (41 views)Galdiero S, Falanga A, Vitiello M, D'Isanto M, Collins C, Orrei V, Browne H, Pedone C, Galdiero M Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 25; 8(8): 885-895.
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* Synthesis, conformation, and bioactivity of novel analogues of the antiviral lipopeptide halovir (50 views)Dalla Bona A, Formaggio F, Peggion C, Kaptein B, Broxterman Quirinus B, Galdiero S, Galdiero M, Vitiello M, Benedetti E, Toniolo C J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 748-757.
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* Structural requirements for proinflammatory activity of porin P2 loop 7 from Haemophilus influenzae (63 views)Galdiero S, Vitiello M, Amodeo P, D'Isanto M, Cantisani M, Pedone C, Galdiero M Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Apr 11; 45(14): 4491-4501.
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* Fusogenic domains in herpes simplex virus type 1 glycoprotein (50 views)Galdiero S, Falanga A, Vitiello M, Browne H, Pedone C, Galdiero M J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2005 Sep 5; 280(31): 28632-28643.
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* Induction of signaling pathways by herpes simplex virus type 1 through glycoprotein H peptides (51 views)Galdiero S, Vitiello M, D'Isanto M, Di Niola E, Peluso L, Raieta K, Pedone C, Galdiero M, Benedetti E Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 494-502.
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* Fusion in Coq (50 views)Vitiello M, Finamore E, Falanga A, Raieta K, Cantisani M, Galdiero F, Pedone C, Galdiero M, Galdiero S Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2001; 2178LNCS: 583-596.
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The crystal structure of a Dcp-containing peptide (50 views)De Simone G, Lombardi A, Galdiero S, Nastri F, Di Costanzo L, Gohda S, Sano A, Yamada T, Pavone V Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000 Feb; 53(2): 182-188.
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The crystal structure of Afc-containing peptide (45 views)Lombardi A, De Simone G, Galdiero S, Nastri F, Di Costanzo L, Makihiara K, Yamada T, Pavone V Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000 Feb; 53(2): 150-160.
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Crystallization and preliminary X-ray diffraction studies of the carboxylesterase EST2 from Alicyclobacillus acidocaldarius (41 views)De Simone G, Manco G, Galdiero S, Lombardi A, Rossi M, Pavone V Acta Crystallogr Sect D Biol Crystallogr Acta Crystallographica Section D Biological Crystallography (ISSN: 0907-4449), 1999 Jul; 55(7): 1348-1349.
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From natural to synthetic multisite thrombin inhibitors (51 views)Lombardi A, De Simone G, Galdiero S, Staiano N, Nastri F, Pavone V Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1999; 51(1): 19-39.
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Conformational Characterization Of Peptides Rich In The Cycloaliphatic C Alpha, Alpha-Disubstituted Glycine 1-Aminocyclononane-1-Carboxylic Acid (47 views)Gatos M, Formaggio F, Crisma M, Valle G, Toniolo C, Bonora GM, Saviano M, Iacovino R, Menchise V, Galdiero S, Pedone C, Benedetti E J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 1997 Sep; 3(5): 367-382.
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Synthesis And Structural Characterization Of 6i, 6ii-Diamino-6i, 6ii-Dideoxy-Cyclomaltoheptaose, A Difunctionalized Beta-Cyclodextrin (40 views)Di Blasio B, Galdiero S, Saviano M, Pedone C, Benedetti E, Rizzarelli E, Pedotti S, Vecchio G, Gibbons WA Carbohydr Res, 1996 Feb 28; 282(1): 41-52.
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Functionalized cyclodextrins: Synthesis and structural characterization of 6-deoxy-6-{4-[N-tert-butoxycarbonyl-2-aminoethyl]-imidazolyl}-cyclomaltoheptaose (43 views)Di Blasio B, Galdiero S, Saviano M, De Simone G, Benedetti E, Pedone C, Gibbons WA, Deschenaux R, Rizzarelli E, Vecchio G Supramol Chem Supramolecular Chemistry (ISSN: 1061-0278), 1996; 7(1): 47-54.
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71 Records ( 66 excluding Abstracts and Conferences). Total impact factor: 233.899 ( 220.231 excluding Abstracts and Conferences). Total 5-year impact factor: 249.633 ( 234.568 excluding Abstracts and Conferences).
Your bibliography query: [author] GALDIERO_S
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