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 | | Name | Vincenzo Alterio | | Area | Research and Development | | Position | Researcher | | Work site | Naples - Mezzocannone | | Address | Via Mezzocannone 16, 80134 Naples - Italy | | E-mail | vincenzo.alterio@ibb.cnr.it |
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Dr. Vincenzo Alterio was born in Naples on 16/06/1975. He graduated in Chemistry at the University of Naples “Federico II” in 2001 and received his Ph.D. in Chemical Sciences from the same University in 2004. In 2006 he has been visiting scientist at the Biochemistry Institute of the University of Luebeck (Germany). Since 2009, he is researcher at the Institute of Biostructures and Bioimaging. His main research activity is focused on the study of structure/function relationships in biological systems having medical and/or biotechnological interest. These studies are carried out by Dr. Alterio by means of several experimental methodologies, including X-ray crystallography, absorption and emission spectroscopy and molecular biology. In particular, Dr. Alterio has a high experience in the most powerful structural resolution techniques in the field of X-ray crystallography, for the determination of protein structures. In this field Dr. Alterio expertise covers all stages of a structural determination: crystallization, data collection by both conventional and synchrotron sources, structure resolution by means of different phasing methodologies, including molecular replacement, MAD and SAD, model refinement. Dr. Alterio is author of 34 scientific publications on international journals among which PNAS, JACS, Chem. Rev. Currently He is member of the editorial board of two international journals. |
Bibliography ▼
<=2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 ALL YEARS
Sort by: date ▼▲ title ▲ ▼ journal ▲ ▼ authors ▲ ▼ impact factor ▲ ▼* Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements (6 views)Buonanno M, Langella E, Zambrano N, Succoio M, Sasso E, Alterio V, Di Fiore A, Sandomenico A, Supuran CT, Scaloni A, Monti SM, De Simone G Acs Chem Biol (ISSN: 1554-8937electronic, 1554-8929linking), 2017 Apr 19; N/D: N/D-N/D.
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* Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides (14 views)BrunoE, Buemi MR, Di Fiore A, De Luca L, Ferro S, Angeli A, Cirilli R, Sadutto D, Alterio V, Monti SM, Supuran CT, De Simone G, Gitto R J Med Chem, 2017 Apr; N/D: N/D-N/D.
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* Benzoxaborole as a new chemotype for carbonic anhydrase inhibition (27 views)Alterio V, Cadoni R, Esposito D, Vullo D, Fiore AD, Monti SM, Caporale A, Ruvo M, Sechi M, Dumy P, Supuran CT, De Simone G, Winum JY Chem Commun (ISSN: 1364-548xelectronic, 1359-7345linking), 2016 Sep 29; 52(80): 11983-11986.
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* Discovery of 1, 1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors (75 views)La Regina G, Coluccia A, Famiglini V, Pelliccia S, Monti L, Vullo D, Nuti E, Alterio V, De Simone G, Monti SM, Pan P, Parkkila S, Supuran CT, Rossello A, Silvestri R J Med Chem (ISSN: 1520-4804electronic, 0022-2623linking, 0022-2623print), 2015 Nov 12; 58(21): 8564-8572.
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* Hydroxylamine-O-sulfonamide is a versatile lead compound for the development of carbonic anhydrase inhibitors (95 views) (PDF 71 views)Di Fiore A, Vergara A, Caterino M, Alterio V, Monti SM, Ombouma J, Dumy P, Vullo D, Supuran CT, Winum JY, De Simone G Chem Commun (ISSN: 1364-548xelectronic, 1359-7345linking), 2015 Jul 2; 51(57): 11519-11522.
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* Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense (51 views)De Simone G, Monti SM, Alterio V, Buonanno M, De Luca V, Rossi M, Carginale V, Supuran CT, Capasso C, Di Fiore A Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2015 May 1; 25(9): 2002-2006.
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* X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor (92 views)Alterio V, Tanc M, Ivanova J, Zalubovskis R, Vozny I, Monti SM, Di Fiore A, De Simone G, Supuran CT Org Biomol Chem (ISSN: 1477-0539electronic, 1477-0520linking), 2015 Apr 7; 13(13): 4064-4069.
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* Recent developments of carbonic anhydrase inhibitors as potential drugs (50 views)Iqbal J, Al-rashida M, Durdagi S, Alterio V, Di Fiore A Biomed Res Int (ISSN: 2314-6133, 2314-6141, 2314-6141electronic), 2015; 2015: 174178-174178.
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* Biochemical Characterization Of The Chloroplastic β-Carbonic Anhydrase From Flaveria Bidentis (l. ) "kuntze" (74 views)Dathan NA, Alterio V, Troiano E, Vullo D, Ludwig M, De Simone G, Supuran CT, Monti SM J Enzyme Inhib Med Chem (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2014; 29(4): 500-504.
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* Hydrophobic substituents of the phenylmethylsulfamide moiety can be used for the development of new selective carbonic anhydrase inhibitors (64 views)De Simone G, Pizika G, Monti SM, Di Fiore A, Ivanova J, Vozny I, Trapencieris P, Zalubovskis R, Supuran CT, Alterio V Biomed Res Int (ISSN: 2314-6133, 2314-6141, 2314-6141electronic), 2014; 2014: 523210-523210.
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* Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates (101 views)Rami M, Dubois L, Parvathaneni NK, Alterio V, van Kuijk SJ, Monti SM, Lambin P, De Simone G, Supuran CT, Winum JY J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2013 Nov 14; 56(21): 8512-8520.
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* Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii (77 views)Alterio V, Langella E, Viparelli F, Vullo D, Ascione G, Dathan NA, Morel FM, Supuran CT, De Simone G, Monti SM Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 May; 94(5): 1232-1241.
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* Molecular organization of the cullin E3 ligase adaptor KCTD11 (60 views)Correale S, Pirone L, Di Marcotullio L, De Smaele E, Greco A, Mazzà D, Moretti M, Alterio V, Vitagliano L, Di Gaetano S, Gulino A, Pedone E Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2011 Apr; 93(4): 715-724.
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* Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis- sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors (74 views)Vitale RM, Alterio V, Innocenti A, Winum JY, Monti SM, De Simone G, Supuran CT J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2009 Oct 8; 52(19): 5990-5998.
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* Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX (99 views)Alterio V, Hilvo M, Di Fiore A, Supuran CT, Pan P, Parkkila S, Scaloni A, Pastorek J, Pastorekova S, Pedone C, Scozzafava A, Monti SM, De Simone G Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2009 Sep 22; 106(38): 16233-16238.
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* Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX (51 views)Alterio V, Vitale RM, Monti SM, Pedone C, Scozzafava A, Cecchi A, De Simone G, Supuran CT J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2006 Jun 28; 128(25): 8329-8335.
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* Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (89 views)Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Mar 14; 45(10): 3226-3234.
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37 Records ( 37 excluding Abstracts and Conferences). Total impact factor: 215.966 ( 215.966 excluding Abstracts and Conferences). Total 5-year impact factor: 217.898 ( 217.898 excluding Abstracts and Conferences).
Your bibliography query: [author] ALTERIO_V
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