Sandomenico A, Ruggiero A, Iaccarino E, Oliver A, Squeglia F, Moreira M, Esposito L, Ruvo M, Berisio R
Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic), 2023 May 10; 24(10): 500-519.
Romano M, Squeglia F, Kramarska E, Barra G, Choi HG, Kim HJ, Ruggiero A, Berisio R
A Structural View at Vaccine Development against M. tuberculosis
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2023 Jan 14; 12(2): N/D-N/D.
Ruggiero A, Choi HG, Barra G, Squeglia F, Back YW, Kim HJ, Berisio R
Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis
Front Mol Biosci (ISSN: 2296-889xlinking), 2022 Aug 11; 9: 964645-964645.
Squeglia F, Romano M, Esposito L, Barra G, Campiglia P, Sala M, Scala MC, Ruggiero A, Berisio R
Structure-Based Development of SARS-CoV-2 Spike Interactors
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic), 2022 May 17; 23(10): N/D-N/D.
Squeglia F, Marasco D, Ruggiero A, Testa G, Esposito L, Berisio R
Structural and Binding Properties of the Active Cell Wall Hydrolase RipA from M. tuberculosis, a Promising Biosensing Molecule for Early Warning Bacterial Detection
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2022; 29(24): 4282-4292.
Berisio R, Barra G, Romano M, Squeglia F, Ruggiero A
Structural and Biochemical Characterization of Endo- -1, 4-glucanase from Dictyoglomus thermophilum, a Hyperthermostable and Halotolerant Cellulase
Catalysts, 2022; 302: N/D-N/D.
Kramarska E, Squeglia F, De Maio F, Delogu G, Berisio R
PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2021 Jan 15; 10(1): N/D-N/D.
Squeglia F, Romano M, Ruggiero A, Maga G, Berisio R
Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins
Front Chem (ISSN: 2296-2646linking), 2020 Dec 10; 8: 602162-602162.
Squeglia F, Maciejewska B, Łątka A, Ruggiero A, Briers Y, Drulis-kawa Z, Berisio R
Structural and Functional Studies of a Klebsiella Phage Capsule Depolymerase Tailspike: Mechanistic Insights into Capsular Degradation
Structure (ISSN: 0969-2126linking, 1878-4186), 2020 Jun 2; 28(6): 613-624.
Romano M, Ruggiero A, Squeglia F, Maga G, Berisio R
A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2020 May 20; 9(5): 1297-1297.
Calvanese L, Squeglia F, Romano M, D'Auria G, Falcigno L, Berisio R
Structural and dynamic studies provide insights into specificity and allosteric regulation of Ribonuclease AS, a key enzyme in mycobacterial virulence
J Biomol Struct Dyn (ISSN: 0739-1102linking, 1538-0254electronic), 2020; N/D: 1-19.
Smaldone G, Ruggiero A, Balasco N, Abuhammad A, Autiero I, Caruso D, Esposito D, Ferraro G, Gelardi E, L , M , Moreira M, Quareshy M, Romano M, Saaret A, Selvam I, Squeglia F, Troisi R, Kroon-batenburg L, M , J , Esposito L, Berisio R, Vitagliano L
The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xlinking), 2019 Nov 1; 75(Pt11): 707-713.
Squeglia F, Moreira M, Ruggiero A, Berisio R
The Cell Wall Hydrolytic NlpC/P60 Endopeptidases in Mycobacterial Cytokinesis: A Structural Perspective
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2019 Jun 18; 8(6): N/D-N/D.
De Maio F, Squeglia F, Goletti D, Delogu G
The Mycobacterial HBHA Protein: a Promising Biomarker for Tuberculosis
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2018 Oct 29; 26(11): 2051-2060.
Majkowska-skrobek G, Latka A, Berisio R, Squeglia F, Maciejewska B, Briers Y, Drulis-kawa Z
Phage-Borne Depolymerases Decrease Klebsiella pneumoniae Resistance to Innate Defense Mechanisms
Front Microbiol (ISSN: 1664-302xprint, 1664-302xlinking, 1664-302xelectronic), 2018 Oct 23; 9(OCT): 2517-2517.
Squeglia F, Ruggiero A, Berisio R
Collagen degradation in tuberculosis pathogenesis: the biochemical consequences of hosting an undesired guest
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2018 Oct 11; 475(19): 3123-3140.
Calvanese L, Falcigno L, Squeglia F, Berisio R, D'Auria G
PASTA sequence composition is a predictive tool for protein class identification
Amino Acids (ISSN: 1438-2199electronic, 0939-4451linking), 2018 Oct; 50(10): 1441-1450.
Squeglia F, Ruggiero A, Berisio R
Chemistry of Peptidoglycan in Mycobacterium tuberculosis Life Cycle: An off-the-wall Balance of Synthesis and Degradation
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2018 Feb 21; 24
(11
): 2533-2546.
Squeglia F, Ruggiero A, De Simone A, Berisio R
A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Feb; 27(2): 369-380.
Squeglia F, Berisio R, Ruggiero A
The novel thermostable cellulose-degrading enzyme DtCel5H from Dictyoglomus thermophilum: crystallization and X-ray crystallographic analysis
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xelectronic, 2053-230xlinking), 2018 Jan 1; 74(Pt1): 1-5.
Squeglia F, Ruggiero A, Berisio R
Chemistry of Peptidoglycan in Mycobacterium tuberculosis life style: an off-the-wall balance of synthesis and degradation
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018; 24: 2533-2546.
Mcnitt DH, Choi SJ, Keene DR, Van De Water L, Squeglia F, Berisio R, Lukomski S
Surface-exposed loops and an acidic patch in the Scl1 protein of group A Streptococcus enable Scl1 binding to wound-associated fibronectin
J Biol Chem, 2018; N/D: N/D-N/D.
Squeglia F, Berisio R, Shibuya N, Kaku H
Defense Against Pathogens: Structural Insights into the Mechanism of Chitin Induced Activation of Innate Immunity
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3980-3986.
Berisio R, Squeglia F, Ruggiero A
Editorial: Molecular Scenarios Behind Infectious Diseases
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3939-3941.
Squeglia F, Romano M, Ruggiero A, Berisio R
Molecular players in Tuberculosis drug development: another break in the cell wall
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3954-3969.
Calvanese L, Falcigno L, Squeglia F, D'Auria G, Berisio R
PASTA in Penicillin Binding Proteins and Serine/Threonine Kinases: A Recipe of Structural, Dynamic and Binding Properties
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 4038-4056.
Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R
Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2017 May; 35(6): 1322-1330.
Lukomski S, Bachert B, Squeglia F, Berisio R
Collagen-like proteins of pathogenic streptococci
Mol Microbiol (ISSN: 0950-382x), 2017; 103: 919-930.
Berisio R, Ruggiero A, Squeglia F, Esposito C, Molinaro A, Silipo A, Marchetti R, Shibuya N
Molecular mechanisms of defense response induced by chitin oligosaccharides
Research Reports, 2017; N/D: N/D-N/D.
Calvanese L, Falcigno L, Squeglia F, D'Auria G, Berisio R
Structural and dynamic features of PASTA domains with different functional roles
Journal Of Biomolecular Structure & Dynamics, 2017; 35(10): 2293-2300.
Majkowska-skrobek G, Latka A, Berisio R, Maciejewska B, Squeglia F, RomanoM, Lavigne R, Struve C, Drulis-kawa Z
Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy
Viruses (ISSN: 1999-4915, 1999-4915linking, 1999-4915electronic), 2016 Dec 1; 8(12): N/D-N/D.
Bachert BA, Choi SJ, Lasala PR, Harper TI, Mcnitt DH, Boehm DT, Caswell CC, Ciborowski P, Keene DR, Flores AR, Musser JM, Squeglia F, Marasco D, Berisio R, Lukomski S
Unique Footprint in the scl1. 3 Locus Affects Adhesion and Biofilm Formation of the Invasive M3-Type Group A Streptococcus
Front Cell Infect Mi (ISSN: 2235-2988), 2016 Aug 31; 6: 90-90.
Ruggiero A, Squeglia F, Romano M, Berisio R
Use of hydrolytic enzymes for algal biomass treatment
Current Biotechnology, 2016; 5: 296-304.
Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R
The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2015 Nov 5; 1860(2): 445-451.
Romano M, Squeglia F, Berisio R
Structure and Function of RNase AS, a Novel Virulence Factor from Mycobacterium Tuberculosis
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Apr 17; 22(14): 1745-1756.
Squeglia F, Ruggiero A, Berisio R
Exit from mycobacterial dormancy: a structural perspective
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Feb 9; 22(14): 1698-1709.
Berisio R, Squeglia F, Ruggiero A, Petraccone L, Stellato MI, Del Vecchio P
Differential thermodynamic behaviours of the extra-cellular regions of two Ser/Thr PrkC kinases revealed by calorimetric studies
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2015 Feb 8; 1854(5): 402-409.
Squeglia F, Ruggiero A, Romano M, Vitagliano L, Berisio R
Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: Evidence for the l-to-d inversion of configuration of the catalytic cysteine
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2014 Sep; 70(9): 2295-2300.
Calvanese L, Falcigno L, Maglione C, Marasco D, Ruggiero A, Squeglia F, Berisio R, D'Auria G
Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Jul; 101(7): 712-719.
Squeglia F, Bachert B, De Simone A, Lukomski S, Berisio R
The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2014 Feb 21; 289(8): 5122-5133.
Hayafune M, Berisio R, Marchetti R, Silipo A, Kayama M, Desaki Y, Arima S, Squeglia F, Ruggiero A, Tokuyasu K, Molinaro A, Kaku H, Shibuya N
Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2014 Jan 21; 111(3): E404-E404.
Squeglia F, Bachert B, Romano M, Lukomski S, Berisio R
Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2. 3, a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Sep; 69(9): 1023-1025.
Squeglia F, Romano M, Ruggiero A, Vitagliano L, De Simone A, Berisio R
Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jun 4; 104(11): 2530-2539.
Ruggiero A, Marchant J, Squeglia F, Makarov V, De Simone A, Berisio R
Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2013 Feb 1; 31(2): 195-205.
Ruggiero A, De Simone P, Smaldone G, Squeglia F, Berisio R
Bacterial cell division regulation by Ser/Thr kinases: A structural perspective
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2012 Dec; 13(8): 756-766.
Berisio R, Ciccarelli L, Squeglia F, De Simone A, Vitagliano L
Structural and Dynamic properties of incomplete immunoglobulin-like fold domains
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1045-1053.
Ruggiero A, Smaldone G, Squeglia F, Berisio R
Enhanced crystallizability by protein engineering approaches: A general overview
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Jul; 19(7): 732-742.
Squeglia F, Marchetti R, Ruggiero A, Lanzetta R, Marasco D, Dworkin J, Petoukhov M, Molinaro A, Berisio R, Silipo A
Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2011 Dec 28; 133(51): 20676-20679.
Ruggiero A, Squeglia F, Marasco D, Marchetti R, Molinaro A, Berisio R
X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2011 Apr 1; 435(1): 33-41.
Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Ruggiero A, Squeglia F, Izzo V, Silipo A, Vitagliano L, Molinaro A, Berisio R
Expression, purification, crystallization and preliminary x-ray crystallographic analysis of the peptidoglycan binding region of the ser/thr kinase PrkC from staphylococcus aureus
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Oct; 17(10): 1296-1299.
Ruggiero A, Marasco D, Squeglia F, Soldini S, Pedone E, Pedone C, Berisio R
Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation
Structure (ISSN: 0969-2126, 1878-4186, 0969-2126linking), 2010 Sep 8; 18(9): 1184-1190.
Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.