Solid-state optical properties of self-assembling amyloid-like peptides with different charged states at the terminal ends(160 views) Schiattarella C, Diaferia C, Gallo E, Della Ventura B, Morelli G, Vitagliano L, Velotta R, Accardo A
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic), 2022 Jan 14; 12(1): 759-759.
Institute of Applied Sciences and Intelligent Systems, CNR, Via P. Castellino 111, 80131, Naples, Italy.
Department of Pharmacy and Research Centre on Bioactive Peptides (CIRPeB), University of Naples "Federico II", Via Mezzocannone 16, 80134, Naples, Italy.
IRCCS Synlab SDN, Via Gianturco 113, 80143, Naples, Italy.
Department of Physics "Ettore Pancini", University of Naples "Federico II", Via Cintia 26, 80125, Naples, Italy.
Institute of Biostructures and Bioimaging (IBB), CNR, Via Mezzocannone 16, 80134, Naples, Italy.
References: Not available.
Solid-state optical properties of self-assembling amyloid-like peptides with different charged states at the terminal ends
The self-assembling of small peptides not only leads to the formation of intriguing nanoarchitectures, but also generates materials with unexpected functional properties. Oligopeptides can form amyloid-like cross-β assemblies that are able to emit intrinsic photoluminescence (PL), over the whole near-UV/visible range, whose origin is still largely debated. As proton transfer between the peptide chain termini within the assembly is one of the invoked interpretations of this phenomenon, we here evaluated the solid state PL properties of a series of self-assembled hexaphenylalanine peptides characterized by a different terminal charge state. Overall, our data indicate that the charge state of these peptides has a marginal role in the PL emission as all systems exhibit very similar multicolour PL associated with a violation of the Kasha's rule. On the other hand, charged/uncharged ends occasionally produce differences in the quantum yields. The generality of these observations has been proven by extending these analyses to the Aβ(16-21) peptide. Collectively, the present findings provide useful information for deciphering the code that links the spectroscopic properties of these assemblies to their structural/electronic features.
Solid-state optical properties of self-assembling amyloid-like peptides with different charged states at the terminal ends