Effect of acute administration of l-acetyl carnitine on cerebral blood flow in patients with chronic cerebral infarct (461 views)
Pharmacol Res (ISSN: 1043-6618, 1096-1186electronic, 1043-6618linking), 1991 Apr; 23(3): 241-246.
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Paper type: Journal Article,
Impact factor: 0.47, 5-year impact factor: 2.17
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0025767765&partnerID=40&md5=6c0c3fcf8a272a112f6df2e2f96a46a2
Keywords: Brain Imaging, Cerebral Blood Flow, Cerebrovascular Disease, Neuropharmacology, Acetylcarnitine, Xenon 133, Adult, Article, Brain Blood Flow, Chronic Disease, Clinical Article, Controlled Study, Female, Human, Intravenous Drug Administration, Single Photon Emission Computer Tomography, Cerebral Infarction, Cerebrovascular Circulation, Cerebrovascular Disorders, Middle Age, Emission-Computed, Single-Photon,
Affiliations:
Clinica Medica, Institute of Internal Medicine and Metabolic Diseases, 2nd Medical School, Italy
Department of Nuclear Medicine, 2nd Medical School, University of Naples, Italy
Institute of Pharmacology, 2nd Medical School, University of Naples, Italy
References:
Not available.
Pharmacol Res (ISSN: 1043-6618, 1096-1186electronic, 1043-6618linking), 1991 Apr; 23(3): 241-246.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 0.47, 5-year impact factor: 2.17
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0025767765&partnerID=40&md5=6c0c3fcf8a272a112f6df2e2f96a46a2
Keywords: Brain Imaging, Cerebral Blood Flow, Cerebrovascular Disease, Neuropharmacology, Acetylcarnitine, Xenon 133, Adult, Article, Brain Blood Flow, Chronic Disease, Clinical Article, Controlled Study, Female, Human, Intravenous Drug Administration, Single Photon Emission Computer Tomography, Cerebral Infarction, Cerebrovascular Circulation, Cerebrovascular Disorders, Middle Age, Emission-Computed, Single-Photon,
Affiliations:
Clinica Medica, Institute of Internal Medicine and Metabolic Diseases, 2nd Medical School, Italy
Department of Nuclear Medicine, 2nd Medical School, University of Naples, Italy
Institute of Pharmacology, 2nd Medical School, University of Naples, Italy
References:
Not available.
Effect of acute administration of l-acetyl carnitine on cerebral blood flow in patients with chronic cerebral infarct
The effect of l-acetyl carnitine (l-AC) on cerebral blood flow (CBF) was evaluated in 20 patients with chronic cerebrovascular disease, who suffered an ischaemic stroke at least 6 months before the study. All patients performed a CT scan and were investigated with xenon-133 by brain dedicated single photon emission computed tomography (SPECT, Tomomatic 32, Medimatic Inc., Copenhagen). A single high dose (1.5 g) of l-acetyl carnitine was intravenously administered to 10 patients, while sodium acetate as placebo was injected to 10 other subjects. Cerebral blood flow (ml/min × 100 g) was evaluated before and 45 min after the injection. No changes were observed after placebo injection (43 ± 12 ml/min × 100 g versus 43 ± 10 ml/min × 100 g). CBF increased (from 42 ± 9 ml/min × 100 g to 46 ± 9, P
The effect of l-acetyl carnitine (l-AC) on cerebral blood flow (CBF) was evaluated in 20 patients with chronic cerebrovascular disease, who suffered an ischaemic stroke at least 6 months before the study. All patients performed a CT scan and were investigated with xenon-133 by brain dedicated single photon emission computed tomography (SPECT, Tomomatic 32, Medimatic Inc., Copenhagen). A single high dose (1.5 g) of l-acetyl carnitine was intravenously administered to 10 patients, while sodium acetate as placebo was injected to 10 other subjects. Cerebral blood flow (ml/min × 100 g) was evaluated before and 45 min after the injection. No changes were observed after placebo injection (43 ± 12 ml/min × 100 g versus 43 ± 10 ml/min × 100 g). CBF increased (from 42 ± 9 ml/min × 100 g to 46 ± 9, P
Effect of acute administration of l-acetyl carnitine on cerebral blood flow in patients with chronic cerebral infarct
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Effect of acute administration of l-acetyl carnitine on cerebral blood flow in patients with chronic cerebral infarct
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View Export to BibTeX Export to EndNote
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View Export to BibTeX Export to EndNote
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View Export to BibTeX Export to EndNote
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Impact Factor: 3.935
View Export to BibTeX Export to EndNote
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Impact Factor: 4.128
View Export to BibTeX Export to EndNote
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Impact Factor: 2.3
View Export to BibTeX Export to EndNote
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View Export to BibTeX Export to EndNote
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View Export to BibTeX Export to EndNote
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Impact Factor: 0.343
View Export to BibTeX Export to EndNote
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View Export to BibTeX Export to EndNote
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Impact Factor: 4.323
View Export to BibTeX Export to EndNote
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View Export to BibTeX Export to EndNote
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Impact Factor: 0
View Export to BibTeX Export to EndNote
23 Records (17 excluding Abstracts).
Total impact factor: 87.914 (64.561 excluding Abstracts).
Total 5 year impact factor: 100.25 (74.467 excluding Abstracts).
Total impact factor: 87.914 (64.561 excluding Abstracts).
Total 5 year impact factor: 100.25 (74.467 excluding Abstracts).
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